Isoflavonoids from Pueraria mirifica and their estrogenic activity
- PMID:10985090
- DOI: 10.1055/s-2000-8603
Isoflavonoids from Pueraria mirifica and their estrogenic activity
Abstract
Nine isoflavonoids including a new pterocarpene, puemiricarpene, were isolated from the tuberous root of Pueraria mirifica (Leguminosae). The structure of puemiricarpene was determined by spectroscopic means. Estrogenic activity of the isolated isoflavonoids was tested using MCF-7 human breast cancer cells. Moderate activity was observed for kwakhurin, a prenylated isoflavonoid.
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