Review
doi: 10.1016/s0168-9525(99)01776-x.Pax 6: mastering eye morphogenesis and eye evolution
Affiliations
- PMID:10461206
- DOI: 10.1016/s0168-9525(99)01776-x
Item in Clipboard
Review
Pax 6: mastering eye morphogenesis and eye evolution
W J Gehring et al. Trends Genet.1999 Sep.
Display options
Format
Display options
Format
Abstract
Pax 6 genes from various animal phyla are capable of inducing ectopic eye development, indicating that Pax 6 is a master control gene for eye morphogenesis. It is proposed that the various eye-types found in metazoa are derived from a common prototype, monophyletically, by a mechanism called intercalary evolution.
Comment in
- The eye: monophyletic, polyphyletic or perhaps biphyletic?Meyer-Rochow VB.Meyer-Rochow VB.Trends Genet. 2000 Jun;16(6):244-5. doi: 10.1016/s0168-9525(00)02019-9.Trends Genet. 2000.PMID:10827449No abstract available.
Similar articles
- The master control gene for morphogenesis and evolution of the eye.Gehring WJ.Gehring WJ.Genes Cells. 1996 Jan;1(1):11-5. doi: 10.1046/j.1365-2443.1996.11011.x.Genes Cells. 1996.PMID:9078363Review.
- Isolation and expression of a Pax-6 gene in the regenerating and intact Planarian Dugesia(G)tigrina.Callaerts P, Munoz-Marmol AM, Glardon S, Castillo E, Sun H, Li WH, Gehring WJ, Salo E.Callaerts P, et al.Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):558-63. doi: 10.1073/pnas.96.2.558.Proc Natl Acad Sci U S A. 1999.PMID:9892672Free PMC article.
- Isolation and developmental expression of the amphioxus Pax-6 gene (AmphiPax-6): insights into eye and photoreceptor evolution.Glardon S, Holland LZ, Gehring WJ, Holland ND.Glardon S, et al.Development. 1998 Jul;125(14):2701-10. doi: 10.1242/dev.125.14.2701.Development. 1998.PMID:9636084
- Role of Pax genes in eye evolution: a cnidarian PaxB gene uniting Pax2 and Pax6 functions.Kozmik Z, Daube M, Frei E, Norman B, Kos L, Dishaw LJ, Noll M, Piatigorsky J.Kozmik Z, et al.Dev Cell. 2003 Nov;5(5):773-85. doi: 10.1016/s1534-5807(03)00325-3.Dev Cell. 2003.PMID:14602077
- Pax-6, eyes absent, and Prox 1 in eye development.Tomarev SI.Tomarev SI.Int J Dev Biol. 1997 Dec;41(6):835-42.Int J Dev Biol. 1997.PMID:9449459Review.
Cited by
- Ocular aldehyde dehydrogenases: protection against ultraviolet damage and maintenance of transparency for vision.Chen Y, Thompson DC, Koppaka V, Jester JV, Vasiliou V.Chen Y, et al.Prog Retin Eye Res. 2013 Mar;33:28-39. doi: 10.1016/j.preteyeres.2012.10.001. Epub 2012 Oct 23.Prog Retin Eye Res. 2013.PMID:23098688Free PMC article.Review.
- The road to generating transplantable organs: from blastocyst complementation to interspecies chimeras.Zheng C, Ballard EB, Wu J.Zheng C, et al.Development. 2021 Jun 15;148(12):dev195792. doi: 10.1242/dev.195792. Epub 2021 Jun 16.Development. 2021.PMID:34132325Free PMC article.
- Selectionism and neutralism in molecular evolution.Nei M.Nei M.Mol Biol Evol. 2005 Dec;22(12):2318-42. doi: 10.1093/molbev/msi242. Epub 2005 Aug 24.Mol Biol Evol. 2005.PMID:16120807Free PMC article.
- Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype.Goudreau G, Petrou P, Reneker LW, Graw J, Löster J, Gruss P.Goudreau G, et al.Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8719-24. doi: 10.1073/pnas.132195699. Epub 2002 Jun 18.Proc Natl Acad Sci U S A. 2002.PMID:12072567Free PMC article.
- Patterns of gene expression: homology or homocracy?Nielsen C, Martinez P.Nielsen C, et al.Dev Genes Evol. 2003 Apr;213(3):149-54. doi: 10.1007/s00427-003-0301-4. Epub 2003 Feb 18.Dev Genes Evol. 2003.PMID:12690454
Publication types
MeSH terms
Substances
Related information
LinkOut - more resources
Full Text Sources
Medical
Molecular Biology Databases