Intensive care unit dignified care: Development and validation of a questionnaire.Andong Liang,Wenxian Xu,Yucong Shen,Qiongshuang Hu,Zhenzhen Xu,Peipei Pan,Zhongqiu Lu &Yeqin Yang -2022 -Nursing Ethics 29 (7-8):1683-1696.detailsBackground Patient dignity is sometimes neglected in intensive care unit (ICU) settings, which may potentially cause psychological harm to critically ill patients. However, no instrument has been specifically developed to evaluate the behaviors of dignified care among critical care nurses. Aim This study aimed to develop and evaluate ICU Dignified Care Questionnaire (IDCQ) for measurement of self-assessed dignity-conserving behaviors of critical care nurses during care. Methods The instrument was developed in 3 phases. Phase 1: item generation; phase 2: a two-round (...) Delphi survey and a readability pilot study; phase 3: cross-sectional survey with model estimation. The questionnaire was evaluated by item analysis, exploratory and confirmatory factor analysis, assessment of internal consistency reliability, and test-retest reliability. The investigation was conducted using a convenience sample of 392 critical care nurses from 6 cities in Zhejiang Province, China, of which 30 participated in the test-retest reliability survey 2 weeks later. Ethical considerations The study was approved by ethics committee. All participants provided written informed consent before the survey. The questionnaire survey was anonymous. Results The results showed acceptable reliability and validity of the IDCQ. The 17-item final version questionnaire was divided into 2 dimensions: absolute dignity and relative dignity. These two factors accounted for 62.804% of the total variance, and model fitting results were acceptable. The Cronbach’s alpha coefficient of the questionnaire was 0.94, and the test-retest intraclass correlation coefficient (ICC) was 0.88 after 2 weeks. Conclusions This study developed a brief and reliable instrument (IDCQ) to assess dignified care in ICU nursing. It can help critical care nurses identify their behaviors in maintaining patient dignity and discover their deficiencies. It may also serve as a clinical nursing management tool to help reduce patient disrespect experience in ICU. (shrink)
Kant on Lazy Savagery, Racialized.Huaping Lu-Adler -2022 -Journal of History of Philosophy 60 (2):253-75.detailsKant develops a concept of savagery, partly characterized by laziness, to envision a program for human progress. He also racializes savagery, treating native Americans, in particular, as literal savages. He ascribes to this “race” a peculiar physiological laziness, a supposedly hereditary trait of blunted life power. Accordingly, while he grants them the same “germs” for perfections as he does the civilized Europeans, he allows them no prospect of actually fulfilling any such perfection. For the road to perfection must be paved (...) through industry, a condition that Kant denies to the “savages” by racializing their alleged laziness. This case will shed new light on the debated relation between Kant’s moral universalism and his racism. (shrink)
Kant on public reason and the linguistic Other.Huaping Lu-Adler -2024 -Asian Journal of Philosophy 3 (2):1-22.detailsOn Kant’s account, “public use of reason” is the use that a truth-seeking scholar makes of his reason when he communicates his thoughts in writing to a world of readers. Commentators tend to treat this account as expressing an egalitarian ideal, without taking seriously the limiting conditions—especially the scholarship condition—built into it. In this paper, I interrogate Kant’s original account of public reason in connection with his construction of the “Oriental” as a linguistically and therefore epistemically and culturally inferior Other. (...) I thereby give reasons to worry that Kant’s account is substantively inegalitarian (even if it is nominally egalitarian). I also draw attention to the fact that Kant constructed a linguistic Other against the backdrop of colonialism and from a position of power. This positionality gave what he said about the Other an ideology-forming and world-making effect. In this way, his exclusionary discursive practices—such as depicting the Oriental as an inferior linguistic Other—could have a lasting impact on knowledge production and on the real-world exercise of public reason. (shrink)
Kant's Use of Travel Reports in Theorizing about Race -A Case Study of How Testimony Features in Natural Philosophy.Huaping Lu-Adler -2022 -Studies in History and Philosophy of Science Part A 91 (C):10-19.detailsA testimony is somebody else’s reported experience of what has happened. It is an indispensable source of knowledge. It only gives us historical cognition, however, which stands in a complex relation to rational or philosophical cognition: while the latter presupposes historical cognition as its matter, one needs the architectonic “eye of a philosopher” to select, interpret, and organize historical cognition. Kant develops this rationalist theory of testimony. He also practices it in his own work, especially while theorizing about race as (...) a subject of natural philosophy. In three dedicated essays on this subject, he treats race from the standpoint of a philosophical investigator of nature (Naturforscher), who (as Kant puts it in the first Critique) learns from nature “like an appointed judge who compels witnesses to answer the questions he puts to them.” This view underwrites Kant’s use of travel reports (a type of testimony) in developing and defending his theory of race. (shrink)
Slavery and Kant's Doctrine of Right.Huaping Lu-Adler -2025 -History of Modern Philosophy 6 (2).detailsIn the 1780s through the end of 1790s, Kant made various references to slavery (in its different forms) and the transatlantic slave trade in the context of his political philosophy or philosophy of right; he thereby had opportunities to speak in favor of abolitionism, which was gaining momentum in parts of Europe, or at least to articulate a normative critique of the race-based chattel slavery or Atlantic slavery and the associated slave trade qua (legalized) INSTITUTIONS; but he did neither. Why? (...) In raising and seeking an answer to this question, I am not interested in what Kant’s normative silence about the institutions of Atlantic slavery and slave trade may tell us about him as a person (for example, whether he was blinded by his own racist prejudices or whether he was affected by some kind of cognitive dissonance). Rather, I will focus on what it may tell us about certain limitations of his political philosophy, limitations that might have made it THEORETICALLY DIFFICULT for him to figure out exactly what to DO about those institutions as entrenched political realities. (shrink)
Kant on Language and the (Self‐)Development of Reason.Huaping Lu-Adler -2023 -Kant Yearbook 15 (1):109-134.detailsThe origin of languages was a hotly debated topic in the eighteenth century. This paper reconstructs a distinctively Kantian account according to which the origination, progression, and diversification of languages is at bottom reason’s self-development under certain a priori constraints and external environments. The reconstruction builds on three sets of materials. The first is Herder’s famous prize essay on the origin of languages. The second includes Kant’s explicit remarks about language – especially his notion of “transcendental grammar,” his argument that (...) language cannot be innate, his contrast of “Oriental” symbolic (intuitive) and “Occidental” discursive languages, and his treatment of the latter as a sine qua non of humanity’s cultural and moral progress. The third includes the concepts that we need to make sense of those remarks, such as Kant’s epigenetic theory of biological formation and his account of categories as originally acquired. (shrink)
Kant and the Principle of Sufficient Reason.Huaping Lu-Adler -2021 -Review of Metaphysics 74 (3):301–30.detailsLeibniz, and many following him, saw the Principle of Sufficient Reason (PSR) as pivotal to a scientific (demonstrated) metaphysics. Against this backdrop, Kant is expected to pay close attention to PSR in his reflections on the possibility of metaphysics, which is his chief concern in the Critique of Pure Reason. It is far from clear, however, what has become of PSR in the Critique. On one reading, Kant has simply turned it into the causal principle of the Second Analogy. On (...) a different reading, PSR is but the supreme principle of reason, which roughly states that, if the conditioned is given, so is the unconditioned. On my reading, PSR appears in the guises of both the causal principle and the supreme principle. This twofold specification, I argue, is key to understanding (i) Kant’s allegations that past metaphysicians failed to prove PSR, (ii) his own Critical account of the possibility of metaphysics in both of its parts (ontology and metaphysics proper), and (iii) his nuanced answer to the contentious question about the relation between physical inquiry and metaphysical reasoning about nature (both being quests for reasons). (shrink)
On the Difference of Buddhist Theory between Southern and Northern Dynasty and Its Evolution from Southern-Northern Dynasty to Tang Dynasty.Dan-Qiong Zhu &Lu Zhao -2005 -Philosophy of the Social Sciences 35 (3):56-59.detailsConsciousness-only school papers to the theoretical differences in Northern and Southern Dynasties as a special case, analysis of Chinese Buddhism from some of the theoretical differences between Northern and Southern Dynasties to the Sui and Tang dynasties of major change, this process reflects the Buddhist theory of the process of changing some of its inherent orientation choice, also shows that this choice is with the overall development of traditional Chinese culture inseparable. Based on the difference of Buddhist Weishixue theories between (...) the Southern and Northern dynasty, this paper analyzes some theoretical divergence and important change from Southern-Northern dynasty to Tang dynasty, hence the paper considers that this change reflects the immanent tropism in the development of Chinese Buddhism and indicates the theoretical choice under the background of Chinese traditional culture. (shrink)
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Kant on the Logical Form of Singular Judgments.Huaping Lu-Adler -2014 -Kantian Review 19 (3):367-92.detailsAt A71/B96–7 Kant explains that singular judgements are ‘special’ because they stand to the general ones as Einheit to Unendlichkeit. The reference to Einheit brings to mind the category of unity and hence raises a spectre of circularity in Kant’s explanation. I aim to remove this spectre by interpreting the Einheit-Unendlichkeit contrast in light of the logical distinctions among universal, particular and singular judgments shared by Kant and his logician predecessors. This interpretation has a further implication for resolving a controversy (...) over the correlation between the logical moments of quantity (universal, particular, singular) and the categorial ones (unity, plurality, totality). (shrink)
Ontology as Transcendental Philosophy.Huaping Lu-Adler -2018 - In Courtney D. Fugate,Kant's Lectures on Metaphysics: A Critical Guide. Cambridge: Cambridge University Press. pp. 53-73.detailsHow does the critical Kant view ontology? There is no shared scholarly answer to this question. Norbert Hinske sees in the Critique of Pure Reason a “farewell to ontology,” albeit one that took Kant long to bid (Hinske 2009). Karl Ameriks has found evidence in Kant’s metaphysics lectures from the critical period that he “was unwilling to break away fully from traditional ontology” (Ameriks 1992: 272). Gualtiero Lorini argues that a decisive break with the tradition of ontology is essential to (...) Kant’s critical reform of metaphysics, as is reflected in his shift from “ontology” to “transcendental philosophy,” two notions that Lorini takes to be related by mere “analogy” (Lorini 2015). I agree with Lorini that a thorough reform of ontology is a pivotal part of Kant’s critical plan for metaphysics and that ontology somehow “survives within the critical philosophy” (Lorini 2015: 76). To make this case, however, I deem it important to identify “ontology” and “transcendental philosophy” in the sense of extensional equivalence. While we can detect this identification in Kant’s writings, only from his metaphysics lectures can we get a full sense of its historical and philosophical significance. In this chapter I focus on how it represents a definitive turn from as well as notable continuity with traditional treatments of ontology, particularly the Wolffian one. (shrink)
Assessing Lexical Psychological Properties in Second Language Production: A Dynamic Semantic Similarity Approach.Kun Sun &Xiaofei Lu -2021 -Frontiers in Psychology 12.detailsPrevious studies of the lexical psycholinguistic properties in second language production have assessed the degree of an LPP dimension of an L2 corpus by computing the mean ratings of unique content words in the corpus for that dimension, without considering the possibility that learners at different proficiency levels may perceive the degree of that dimension of the same words differently. This study extended a dynamic semantic similarity algorithm to estimate the degree of five different LPP dimensions of several sub-corpora of (...) the Education First-Cambridge Open Language Database representing L2 English learners at different proficiency levels. Our findings provide initial evidence for the validity of the algorithm for assessing the LPPs in L2 production and contribute useful insights into between-proficiency relationships and cross-proficiency differences in the LPPs in L2 production as well as the relationships among different LPP dimensions. (shrink)
A novel framework to unearth corporate hypocrisy: Connotation, formation mechanism, manifestation, and contagion effect.Jintao Lu,Chunyan Wang,Dima Jamali,Yangyang Gao,Chong Zhang &Mengshang Liang -2022 -Business Ethics, the Environment and Responsibility 31 (4):1136-1156.detailsBusiness Ethics, the Environment &Responsibility, Volume 31, Issue 4, Page 1136-1156, October 2022.
A New Tool for Rapid Assessment of Acute Exercise-Induced Fatigue.Yao Lu,Ziyang Yuan,Jiaping Chen,Zeyi Wang,Zhandong Liu,Yanjue Wu,Donglin Zhan,Qingbao Zhao,Mofei Pei &Minhao Xie -2022 -Frontiers in Human Neuroscience 16.detailsBackgroundThere are limited sensitive evaluation methods to distinguish people’s symptoms of peripheral fatigue and central fatigue simultaneously. The purpose of this study is to identify and evaluate them after acute exercise with a simple and practical scale.MethodsThe initial scale was built through a literature review, experts and athlete population survey, and a small sample pre-survey. Randomly selected 1,506 students were evaluated with the initial scale after exercise. Subjective fatigue self-assessments were completed at the same time.ResultsThe Acute Exercise-Induced Fatigue Scale was (...) determined after performing a factor analysis. In the exploratory factor analysis, the cumulative variance contribution rate was 65.464%. The factor loadings of the total 8 questions were 0.661–0.816. In the confirmatory factor analysis, χ2/df = 2.529, GFI = 0.985, AGFI = 0.967, NFI = 0.982, IFI = 0.989, CFI = 0.989, and RMSEA = 0.048. The Cronbach’s alpha coefficient for the scale was 0.872, and it was 0.833 for peripheral fatigue and 0.818 for central fatigue. The intra-class correlation coefficient for the scale was 0.536, and the intra-class correlation coefficients for peripheral fatigue and central fatigue were 0.421 and 0.548, respectively. The correlation coefficient between the total score of the AEIFS and the SFSA score was 0.592.ConclusionOur results demonstrate that the AEIFS can distinguish peripheral fatigue and central fatigue and can also reflect their correlation. This scale can be a useful evaluation tool not only for measuring fatigue after acute exercise but also for guiding reasonable exercise, choosing objective testing indicators, and preventing sports injuries resulting from acute exercise-induced fatigue. (shrink)
Logical Normativity and Rational Agency—Reassessing Locke's Relation to Logic.Huaping Lu-Adler -2018 -Journal of the History of Philosophy 56 (1):75-99.detailsThere is an exegetical quandary when it comes to interpreting Locke's relation to logic.On the one hand, over the last few decades a substantive amount of literature has been dedicated to explaining Locke's crucial role in the development of a new logic in the seventeenth and eighteenth centuries. John Yolton names this new logic the "logic of ideas," while James Buickerood calls it "facultative logic."1 Either way, Locke's Essay is supposedly its "most outspoken specimen" or "culmination."2 Call this reading the (...) 'New Logic interpretation.'On the other hand, from the typical standpoint of a philosopher accustomed to the modern conception of logic, whatever Locke—indeed, whatever most of the... (shrink)
Kant on Proving Aristotle’s Logic as Complete.Huaping Lu-Adler -2016 -Kantian Review 21 (1):1-26.detailsKant claims that Aristotles logic as complete, explain the historical and philosophical considerations that commit him to proving the completeness claim and sketch the proof based on materials from his logic corpus. The proof will turn out to be an integral part of Kant’s larger reform of formal logic in response to a foundational crisis facing it.
Attitudes toward women's familial roles:: Changes in the united states, 1977-1985.Yu-Hsia Lu &Karen Oppenheim Mason -1988 -Gender and Society 2 (1):39-57.detailsChanges between 1977 and 1985 in women's and men's attitudes toward women's familial roles were examined using National Opinion Research Center General Social Survey data. Despite speculation that a backlash against feminism occurred during the late 1970s and early 1980s, and evidence from past studies of a possible slowdown in gender-role attitude change, the data show a significant increase in profeminist views of the wife and mother roles among both women and men. More of this change occurred within cohorts than (...) through cohort succession. With the exception of college-graduate women, whose support for gender equality was high at both periods, the profeminist trend occurred about equally in all sociodemographic subgroups of the population, although even in 1985, men were less feminist in orientation than women. (shrink)
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Self-Support and Loneliness Among Chinese Primary School Students: A Moderated Mediation Model.Zhendong Yao,Lu Pang,Huiying Yu,Hanshi Xiao &Biao Peng -2022 -Frontiers in Psychology 12.detailsThis study examined the effect of self-support on loneliness, the mediation effect of school belonging, and the moderation effect of self-esteem using a sample comprising 1,126 Chinese mainland primary school students, 621 are boys and 505 are girls, and their mean age was 10.51 years. Participants completed questionnaires regarding self-support, loneliness, school belonging and self-esteem. In the model hypothesis, self-support is an independent variable, loneliness is an outcome variable, school belonging is a mediating variable, and self-esteem is a regulatory variable. (...) After controlling the demographic variables, the data were analyzed, and the results showed that: self-support had a significantly negative predictive effect on loneliness; the relation between self-support and loneliness was mediated by school belonging; and the relation between school belonging and loneliness was moderated by self-esteem, supporting the moderated mediation model. Moderated mediation analysis further indicated that the mediated path make loneliness weaker for pupils with higher levels of self-esteem. These results revealed the formation mechanism of loneliness in primary school students and have certain enlightenment significance for the intervention of loneliness in primary school students. These results revealed the formation mechanism of loneliness among primary school students and have significant implications for interventions against loneliness in the primary school context. (shrink)
Not Those Who "all speak with pictures": Kant on Linguistic Abilities and Human Progress.Huaping Lu-Adler -forthcoming - In Luigi Filieri & Konstantin Pollok,Kant on Language. Cambridge University Press.detailsKant ascribes two radically different kinds of language—symbolic or pictorial (qua intuitive) and discursive languages—to the “Oriental” and “Occidental” peoples respectively. By his analysis, having a merely symbolic language suggests that the “Orientals” lack understanding—and hence the ability to form concepts and think in abstracto—as well as genius and spirit. Meanwhile, he establishes discursive language as a sine qua non of the continued progress of humanity, primarily because only by means of words—as opposed to symbols—can one think (not just intuit), (...) signify one’s thoughts exactly, and make them universally communicable. Without such a language, one would not be able to make one’s feelings moral or develop a true moral character. In short, humanity would not be able to obtain its cultural or moral ends without discursive language. -/- These points add up to an exclusionary view of progress according to which the Occidental whites alone are equipped with the requisite discursive skills and other talents (including genius and spirit) to accomplish advanced culture and pursue humanity’s moral destiny. The “Orient,” with its “childish language,” is consigned to the childhood of humanity. In holding this view, Kant has departed from some of his predecessors—such as Leibniz, whose vision of the future of humanity includes an East-West harmony facilitated by a “universal symbolism,” and Rousseau, who exalts a livelier connection with the world mediated by a pictorial language. -/- The contrast with Leibniz and Rousseau also suggests that we cannot chalk up Kant’s exclusionary view of progress to mere personal prejudices. His philosophy is what gives meaning to his statements about the nature of the “Oriental” language. That is, the exclusionary view of progress emerges only when we take into account his anti-Leibnizian conceptualization of symbolic language as merely intuitive, his view that humanity is teleologically oriented toward the unique sort of moralization that he envisioned in the Groundwork, and his view that reason must lead the way in humanity’s progress toward this supposed moral end, wherefore only discursive language can facilitate such progress. (shrink)
The Subjective Deduction and Kant’s Methodological Skepticism.Huaping Lu-Adler -2022 - In Giuseppe Motta, Dennis Schulting & Udo Thiel,Kant's Transcendental Deduction and the Theory of Apperception: New Interpretations. Berlin: De Gruyter. pp. 341-60.detailsThe deduction of categories in the 1781 edition of the Critique of the Pure Reason (A Deduction) has “two sides”—the “objective deduction” and the “subjective deduction”. Kant seems ambivalent about the latter deduction. I treat it as a significant episode of Kant’s thinking about categories that extended from the early 1770s to around 1790. It contains his most detailed answer to the question about the origin of categories that he formulated in the 1772 letter to Marcus Herz. The answer is (...) that categories are generated a priori through a kind of intellectual “epigenesis”. This account leaves unexplained why precisely such and such categories should be generated. While this observation caused Kant to worry about the hypothetical status of the subjective deduction in 1781, he would come to acquiesce in the recognition that the ground of the possibility of categories is itself inscrutable. I call this his “methodological skepticism”. (shrink)
Locke on Scientific Methodology.Huaping Lu-Adler -2021 - In Jessica Gordon-Roth & Shelley Weinberg,The Lockean Mind. New York, NY: Routledge. pp. 277-89.detailsThis chapter brings some much-needed conceptual clarity to the debate about Locke’s scientific methodology. Instead of having to choose between the method of hypothesis and that of natural history (as most interpreters have thought), he would resist prescribing a single method for natural sciences in general. Following Francis Bacon and Robert Boyle, Locke separates medicine and natural philosophy (physics), so that they call for completely different methods. While a natural philosopher relies on “speculative” (causal-theoretical) hypotheses together with natural-history making to (...) explicate phenomena, a medical practitioner must prioritize collecting data about what remedies tend to cure what diseases over hypothesizing about the causes of the latter. (shrink)
The Subjective Deduction and Kant’s Methodological Skepticism.Huaping Lu-Adler -2022 - In Giuseppe Motta, Dennis Schulting & Udo Thiel,Kant's Transcendental Deduction and the Theory of Apperception: New Interpretations. Berlin: De Gruyter. pp. 341-360.detailsThe deduction of categories in the 1781 edition of the Critique of the Pure Reason (A Deduction) has “two sides”—the “objective deduction” and the “subjective deduction”. Kant seems ambivalent about the latter deduction. I treat it as a significant episode of Kant’s thinking about categories that extended from the early 1770s to around 1790. It contains his most detailed answer to the question about the origin of categories that he formulated in the 1772 letter to Marcus Herz. The answer is (...) that categories are generated a priori through a kind of intellectual “epigenesis”. This account leaves unexplained why precisely such and such categories should be generated. While this observation caused Kant to worry about the hypothetical status of the subjective deduction in 1781, he would come to acquiesce in the recognition that the ground of the possibility of categories is itself inscrutable. I call this his “methodological skepticism”. (shrink)
Assessing anxiety during the COVID-19 delta epidemic: Validation of the Chinese coronavirus anxiety scale.Qiaoping Lian,Lu Xia &Daxing Wu -2022 -Frontiers in Psychology 13.detailsThe study aimed to examine the psychometric properties of the coronavirus anxiety scale during the coronavirus disease 2019 delta epidemic. A total of 2,116 participants on the Chinese mainland completed the online survey. We employed exploratory factor analysis and confirmatory factor analysis to investigate the factor structure. The findings showed that the one-factor model of the CAS Chinese version fitted perfectly with the data. The multigroup CFAs showed the measurement invariance across gender and age groups. We also examined the CAS’s (...) internal consistency and convergent and concurrent validity. The results demonstrated that the one-factor model had good reliability and convergent and concurrent validity. Overall, according to our findings, the CAS Chinese version was reliable for measuring coronavirus anxiety during the COVID-19 delta outbreak. (shrink)
A Promising Tropical Medicinal Plant: Taiwan as the Production Hub of Japan's Coca Empire.Shao-li Lu -2024 -Berichte Zur Wissenschaftsgeschichte 47 (4):352-381.detailsBefore World War II, Taiwan became the second-largest coca leaf production base in Asia, second only to Java, contributing to Japan's position as the world's largest exporter of cocaine. While Japan's opium empire has been the subject of extensive academic inquiry, its coca empire has received far less attention. This article explores Taiwan's role in Japan's dual empire of opium and coca, focusing on the environmental and historical factors that enabled the island to rapidly expand coca production. It finds that, (...) in addition to Taiwan's favorable climate for coca cultivation, the island's long-established tea industry provided mature techniques for harvesting and drying the coca leaves. Furthermore, the sugar company supplied the necessary equipment and capital for the extraction of cocaine, becoming a key resource in the industry's development. Learning from the limitations of the opium monopoly—where raw materials were increasingly constrained by international markets—the colonial government sought to promote self-sufficiency in coca production. This strategy not only ensured a stable supply of raw materials but also allowed the coca industry to balance for the declining incomes from opium as international controls tightened. From all angles, the coca industry met Japan's expectations as a “promising drug.”. (shrink)
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A Kantian Interpretation of the Infinite Manifoldness of Evil Incentives in Real Human Life.Chao Lu -2021 -International Philosophical Quarterly 61 (2):207-225.detailsKant defined moral evil as reversing the order between self-love and morality. For many critics, however, his egoistically-orientated notion of self-love fails to make sense of the infinitely manifold incentives of evil under the human condition. Against this criticism, my article will re-interpret Kantian self-love and empirical self-conception from both the transcendental and empirical level, thus offering a transcendental grounding for the empirical manifestations of evil. In this way I will argue that we can explain rather sufficiently the infinite manifoldness (...) of evil incentives in real human life with Kant’s prima facie simplistic definition of evil. (shrink)
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A preclinical study of deep brain stimulation in the ventral tegmental area for alleviating positive psychotic-like behaviors in mice.Chen Lu,Yifan Feng,Hongxia Li,Zilong Gao,Xiaona Zhu &Ji Hu -2022 -Frontiers in Human Neuroscience 16.detailsDeep brain stimulation is a clinical intervention for the treatment of movement disorders. It has also been applied to the treatment of psychiatric disorders such as depression, anorexia nervosa, obsessive-compulsive disorder, and schizophrenia. Psychiatric disorders including schizophrenia, bipolar disorder, and major depression can lead to psychosis, which can cause patients to lose touch with reality. The ventral tegmental area, located near the midline of the midbrain, is an important region involved in psychosis. However, the clinical application of electrical stimulation of (...) the VTA to treat psychotic diseases has been limited, and related mechanisms have not been thoroughly studied. In the present study, hyperlocomotion and stereotyped behaviors of the mice were employed to mimic and evaluate the positive-psychotic-like behaviors. We attempted to treat positive psychotic-like behaviors by electrically stimulating the VTA in mice and exploring the neural mechanisms behind behavioral effects. Local field potential recording and in vivo fiber photometry to observe the behavioral effects and changes in neural activities caused by DBS in the VTA of mice. Optogenetic techniques were used to verify the neural mechanisms underlying the behavioral effects induced by DBS. Our results showed that electrical stimulation of the VTA activates local gamma-aminobutyric acid neurons, and dopamine neurons, reduces hyperlocomotion, and relieves stereotyped behaviors induced by MK-801 injection. The results of optogenetic manipulation showed that the activation of the VTA GABA neurons, but not DA neurons, is involved in the alleviation of hyperlocomotion and stereotyped behaviors. We visualized changes in the activity of specific types in specific brain areas induced by DBS, and explored the neural mechanism of DBS in alleviating positive psychotic-like behaviors. This preclinical study not only proposes new technical means of exploring the mechanism of DBS, but also provides experimental justification for the clinical treatment of psychotic diseases by electrical stimulation of the VTA. (shrink)
The Poverty of Conceptual Truth: Kant's Analytic/Synthetic Distinction and the Limits of Metaphysics by R. Lanier Anderson. [REVIEW]Huaping Lu-Adler -2018 -Journal of the History of Philosophy 56 (4):761-763.detailsThis book is a masterpiece on Kant's theory of analyticity. It culminates in a new story of how Kant arrived at his mature view. Here is the chief lesson of this story: "the logical conception of the analytic/synthetic distinction is the fundamental idea of analyticity involved in Kant's distinctive, critical project. … [H]is critique of metaphysics crucially depends on the logical conception and cannot be supported by its merely methodological and epistemological ancestors". This passage consolidates two leading theses of the (...) book: Kant has three versions of the analytic/synthetic distinction: a methodological distinction between two ways of knowing, an epistemological one between two kinds of concept... (shrink)
A review of the idiodynamic method as an emerging research method for the investigation of affective variables in second language acquisition. [REVIEW]Miaoyan Lu -2022 -Frontiers in Psychology 13.detailsRecent years have witnessed the influence of the complex dynamic systems theory in the field of second language acquisition. Thus, new research methods have also been introduced to meet the requirements of investigating the dynamic nature of learner-related factors including L2 affective variables. Among the innovative quantitative research methods which is compatible with the CDST is the idiodynamic method, the application of which is on the rise in SLA research. In this paper, an overall introduction to the idiodynamic method is (...) presented first, followed by a review of the existing literature in SLA studies. Then, it is discussed why this innovative research method is suitable to investigate the dynamic nature of L2 learners’ affective variables in the complex network of classroom learning. Also, several relevant research questions that can potentially be formulated and answered using the idiodynamic method are discussed. The paper ends with conclusive remarks on the need for more extensive use of innovative CDST-compatible research methods such as the idiodynamic method in the prospective SLA line of inquiry. (shrink)
Ru jia xian zheng lun =.Zhongqiu Yao -2016 - Hong Kong: CityU HK Press.details兩甲子前,中國戰敗於日本,儒家士大夫遂尋求全面制度變革,行之數千年的堯舜周孔治理之道被棄如敝屣。此後百年,雖有仁人志士守護道統,復興儒學,唯多局限於精神、道德、文化領域,以為儒家未曾塑造、維護良好秩序 ,更不可能行於當世。 本書作者卻力排眾議,為當前中國之制度變革提出「儒家憲政」方案。作者認為,一國憲政當扎根於自身文明,儒家在中國文明中具有特殊地位,這决定了中國憲政必為儒家憲政。 本書上卷「義理」,參考中國數千年的治理實踐,疏解儒家經典,闡明常在常新的中國治理之道;下卷「更化」,探討當下中國通往儒家憲政之路。作者並不準備提出整全的憲制方案,反而保持充分開放的心態。作者認為,唯有 歸宗道統,中國之政治秩序才可趨於良善、穩定,但「人能弘道」,當世君子不能不因時而立制,為此不能不廣泛參照西方的法度。 故「儒家憲政」既不同於自由民主憲政或社會主義憲政,亦有別於「儒教憲政」。作者以為,前者無視中國文明傳統、憑空立憲,而失之於「不及」;後者「生乎今之世,反古之道」,而失之於「過」。儒家憲政中道而行,或可 供有志於治國平天下的賢明君子採擇一二。.