Movatterモバイル変換

BackgroundEthics consult services are well established, but often remain underutilized. Our aim was to identify the barriers and perceptions of the Ethics consult service for physicians, advance practice providers (APPs), and nurses at our urban academic medical center which might contribute to underutilization.MethodsThis was a cross-sectional single-health system, anonymous written online survey, which was developed by the UCSD Health Clinical Ethics Committee and distributed by Survey Monkey. We compare responses between physicians, APPs, and nurses using standard parametric and non-parametric statistical (...) methods. Satisfaction with ethics consult and likelihood of calling Ethics service again were assessed using a 0–100 scale using a 5-likert response structured (0 being “not helpful at all” to 100 being “extremely helpful”) and results presented using box plots and interquartile ranges (IQR).ResultsFrom January to July 2019, approximately 3800 surveys were sent to all physicians, APPs and nurses with a return rate of 5.5—10%. Although the majority of respondents had encountered an ethical dilemma (85–92.1%) only approximately half had ever requested an Ethics consult. The primary reason for physicians never having requested a consult was that they never felt the need for help (41%). For APPs the primary reasons were not knowing an Ethics consult service was available (33.3%) or not knowing how to contact Ethics (27.8%). For nurses, it was not knowing how to contact the Ethics consult service (30.8%) or not feeling the need for help (26.2%). The median satisfaction score (IQR) for Ethics consult services rated on a 0–100 scale, from physicians was 76 (29), for AAPs 89 (49), and nurses 70 (40) (p = 0.62). The median (IQR) of likelihood of consulting Ethics in the future also on a 0–100 scale was 71 (47) for physicians, 69 (45) for APPs, and 61 (45) for nurses (p = 0.79). APP’s and nurses were significantly more likely than physicians to believe that the team did not act on the Ethics consult’s recommendations.ConclusionsBased on the results presented, we were able to identify actionable steps to better engage healthcare providers—and in particular APPs and nurses—and scale up institutional educational efforts to increase awareness of the role of the Ethics consult service at our institution. Actionable steps included implementing a system of ongoing feedback that is critical for the sustainability of the Ethics service role. We hope this project can serve as a blueprint for other hospital-based Ethics consult services to improve the quality of their programs. (shrink)

No categories

Direct download(3 more)   Export citation   Bookmark   5 citations  

Guanxi in China is a very ancient concept embedded in the Confucian concept of life and one that is a ‚hot' topic in that it is currently attracting increasing attention from both Western and Chinese scholars. One aspect of Guanxi which has been the subject of most of the research of late is the influence of Guanxi on firm performance. However, relatively few studies have examined how Guanxi at the individual level is transferred into a firm to influence its financial (...) performance. This study first reclassifies Guanxi into obligatory, reciprocal, and utilitarian types at the individual level as a means to clarifying the confusion brought above from previous studies. It then provides a conceptual framework in which to systematically characterize the link between Guanxi at the individual level and organizational dynamics: that is, how is Guanxi at the individual level shifted to a firm and how does it affect organizational dynamics of that firm at the organizational level. Finally, it provides a deeper understanding of the financial implications of Guanxi to business firms in China. (shrink)

Direct download(4 more)   Export citation   Bookmark   17 citations  

This study investigated the status quo of article retractions by Chinese researchers. The bibliometric information of 834 retractions from the Web of Science SCI-expanded database were downloaded and analysed. The results showed that the number of retractions increased in the past two decades, and misconduct such as plagiarism, fraud, and faked peer review explained approximately three quarters of the retractions. Meanwhile, a large proportion of the retractions seemed typical of deliberate fraud, which might be evidenced by retractions authored by repeat (...) offenders of data fraud and those due to faked peer review. In addition, a majority of Chinese fraudulent authors seemed to aim their articles which contained a possible misconduct at low-impact journals, regardless of the types of misconduct. The system of scientific evaluation, the “publish or perish” pressure Chinese researchers are facing, and the relatively low costs of scientific integrity may be responsible for the scientific integrity. We suggested more integrity education and severe sanctions for the policy-makers, as well as change in the peer review system and transparent retraction notices for journal administrators. (shrink)

Direct download(2 more)   Export citation   Bookmark   8 citations  

Direct download(4 more)   Export citation   Bookmark   5 citations  

Direct download(5 more)   Export citation   Bookmark   7 citations  

Direct download(2 more)   Export citation   Bookmark   4 citations  

Direct download(2 more)   Export citation   Bookmark   5 citations  

Direct download(2 more)   Export citation   Bookmark   3 citations  

Direct download(2 more)   Export citation   Bookmark   1 citation  

This paper presents a diagrammatic notation for visualizing epistemic entities and relations. The notation was created during the Visualizing Worldviews project funded by the University of Toronto’s Jackman Humanities Institute and has been further developed by the scholars participating in the university’s Research Opportunity Program. Since any systematic diagrammatic notation should be based on a solid ontology of the respective domain, we first outline the current state of the scientonomic ontology. We then proceed to providing diagrammatic tools for visualizing the (...) epistemic entities and relations of this ontology. These basic diagramming techniques allow us to construct diagrams of various types for both synchronic and diachronic visualizations. The paper concludes by highlighting some future research directions. As the notation presented here is de facto accepted and used in scientonomy, the paper suggests no modifications. (shrink)

Direct download(3 more)   Export citation   Bookmark   1 citation  

Drawing on the cognitive dissonance theory and the behavioral consistency theory, this study examines whether hypocrisy, proxied by the ethical dissonance between corporate philanthropy and environmental misconducts, triggers auditors to issue modified audit opinions (MAOs), and further investigates the moderating effect of hypocrisy on the relation between financial reporting quality (proxied by discretionary accruals) and MAOs. Using a sample of 20,852 firm-year observations from the Chinese stock market over 2005–2019, our findings reveal that the likelihood of receiving MAOs is significantly (...) higher for hypocritical firms than for their counterparts, suggesting that hypocrisy provides negative soft information about top managers' myopia, immorality and lack of integrity, elicits the perceived distrust from auditors, motivates auditors to have a higher extent of professional skepticism, and eventually triggers MAOs. Moreover, hypocrisy reinforces the negative (positive) relation between financial reporting quality (discretionary accruals) and MAOs. Furthermore, above findings are robust to a variety of sensitivity tests using alternative proxies for modified audit opinions and hypocrisy, as well as different sample compositions, and further our conclusions are still valid after using the propensity score matching approach and two-stage treatment effect regression procedures to control for the endogeneity issue. Lastly, the effect of hypocrisy on MAOs is more pronounced for remedial (ex post) hypocrisy than for preventive (ex ante) hypocrisy. (shrink)

Direct download(2 more)   Export citation   Bookmark   1 citation  

Screen time has become a hot button issue in psychology with researchers fiercely debating its mental effects. If we want to understand the psychological dynamics of technology use, however, a numerical conceptualization of screen time will lead us to gloss over crucial distinctions. To make this point, the present article takes a hermeneutic approach to a negative form of screen time known as ‘phubbing’, which is the practice of snubbing conversational partners in favor of one’s phone. Using interview data, it (...) is demonstrated that whether or not phone use amounts to phubbing, that is, whether or not it tips over and becomes harmful, depends on a host of contextual factors such as relation (who), content (what), purpose (why), timing (when), and communication (how). These findings demonstrate that not all screen time is created equal: what is harmful and inappropriate in one context is benign in another, and vice versa. Simply put, screen time is not a numerical entity whose causal effects we can measure and explain, but a meaningful activity that we must try to understand. (shrink)

Direct download(3 more)   Export citation   Bookmark   1 citation  

No categories

Direct download(2 more)   Export citation   Bookmark   3 citations  

The unsafe behavior of construction workers is one of the most important and direct causes of safety accidents. Managers usually develop effective incentives aimed at regulating worker safety behavior. Due to the large number of workers in construction projects, there are multiple differences in fairness preference, risk preference and ability level, which will lead to the complex effect of the traditional mechanism to regulate workers’ safety behavior. In order to improve the effectiveness of incentive measures for worker safety behavior, this (...) paper takes into account the multiple differences of individual workers’ fairness preference, risk preference and ability level, based on the tournament mechanism to construct a competition incentive model. By designing a tournament reward and salary distribution for heterogeneous workers, the occurrence of unsafe behaviors can be reduced. The study found that in terms of the optimal level of safety investment, workers with risk aversion attitude generally invest higher than that of workers with risk preference, no matter whether they have a strong fairness preference or not; In terms of the distribution of tournament rewards, workers with a risk aversion attitude and a higher level of fairness preference need to be given higher incentives. (shrink)

Direct download(2 more)   Export citation   Bookmark   2 citations  

The paper studies how leaders can break employee silence. Drawing upon self-determination theory, we argue that empowering leadership can activate employees’ intrinsic motivation such that employees are more willing to break the silence at work; furthermore, the effect is stronger when employees have high levels of job autonomy. We collected time-lagged and multi-source data in a large company to test our hypotheses. The results show that empowering leadership can reduce employee silence through enhancing their intrinsic motivation. The mediation effect and (...) and the boundary effect of job autonomy on the mediation effect are all supported. This paper contributes to the literature on leadership, employee silence, and job design characteristics. (shrink)

Direct download(2 more)   Export citation   Bookmark   3 citations  

No categories

Direct download(3 more)   Export citation   Bookmark   3 citations  

Direct download(2 more)   Export citation   Bookmark   3 citations  

Direct download(2 more)   Export citation   Bookmark   2 citations  

Direct download(2 more)   Export citation   Bookmark   3 citations  

Direct download(2 more)   Export citation   Bookmark   1 citation  

The present study constructed a moderated mediation model to examine whether borderline pathological celebrity worship may be associated with higher levels of impulsive buying intent. The mediating role of empathy and the moderating role of gender were also examined. A total of 1,319 participants recruited from a college through the campus network. The results indicated that borderline pathological celebrity worship could positively predict individuals’ impulsive buying intent; the predictive effect of borderline pathological celebrity worship on impulsive buying intent could be (...) mediated by empathy; and gender moderated the predictive effect of borderline pathological celebrity worship on impulsive buying intent. Specifically, relatively higher levels of borderline pathological celebrity worship were found to be associated with higher impulsive buying intent among men. However, this was relatively less significant among women.ConclusionThe results contribute to previous findings by demonstrating that borderline pathological celebrity worship could affect impulsive buying intent. Moreover, the mediating role of empathy and the moderating role of gender were also revealed. (shrink)

Direct download(2 more)   Export citation   Bookmark   1 citation  

We discuss the cardinalities of maximal cofinitary groups under the assumption of $\neg CH$ . We also discuss various open questions in this area.

Direct download(3 more)   Export citation   Bookmark   6 citations  

If F ⊆ NN is an analytic family of pairwise eventually different functions then the following strong maximality condition fails: For any countable H ⊆ NN. no member of which is covered by finitely many functions from F, there is f ∈ F such that for all h ∈ H there are infinitely many integers k such that f(k) = h(k). However if V = L then there exists a coanalytic family of pairwise eventually different functions satisfying this strong maximality (...) condition. (shrink)

Direct download(6 more)   Export citation   Bookmark   5 citations  

Prediction is one of the major challenges in complex systems. The prediction methods have shown to be effective predictors of the evolution of networks. These methods can help policy makers to solve practical problems successfully and make better strategy for the future. In this work, we focus on exporting countries’ data of the International Trade Network. A recommendation system is then used to identify the products that correspond to the production capacity of each individual country but are somehow overlooked by (...) the country. Then, we simulate the evolution of the country’s fitness if it would have followed the recommendations. The result of this work is the combination of these two methods to provide insights to countries on how to enhance the diversification of their exported products in a scientific way and improve national competitiveness significantly, especially for developing countries. (shrink)

No categories

Direct download(3 more)   Export citation   Bookmark   2 citations  

The effect of authentic leadership and leader competency on employee job performance has received growing attention in the past decades; however, few studies have simultaneously integrated these two leadership perspectives. We have thus developed a mediated moderation model to test the interactive effect of authentic leadership and competency on followers’ job performance through work engagement. Based on a sample of 248 subordinate–supervisor pairs, hierarchical regression analyses reveal that authentic leadership positively relates to followers’ task performance and organizational citizenship behavior ; (...) leader competency moderates the relationship between authentic leadership and OCB; and followers’ work engagement mediates the main effect of authentic leadership and the interactive effect of authentic leadership and competency on followers’ task performance and OCB. All the three results are consistent with our hypotheses. (shrink)

Direct download(2 more)   Export citation   Bookmark   2 citations  

Direct download(2 more)   Export citation   Bookmark   2 citations  

Maimonides (1135/1138–1204) and Zhu Xi 朱熹 (1130–1200) are unparalleled in the transformation and revitalization of Jewish and Confucian traditions, respectively. This article offers a comparative analysis of the two philosophers’ conceptions of nature and their view on the end of knowledge. It examines, on one hand, Maimonides’s distinctive interpretation of the rabbinic concept of maʿaseh bereshith (the Account of the Beginning) in the light of his statement that maʿaseh bereshith is identical with natural science; and on the other hand, Zhu (...) Xi’s elucidation of key concepts such as xing 性 (nature), shu 數 (number), tian 天 (heaven), and cheng 誠 (genuineness) in the framework of his doctrine of li 理 (pattern or principle) and qi 氣 (material force). The article points out that Maimonides not only connects the maʿaseh bereshith to the beginning of the world, as traditionally held; he also associates it with the beginning of the revelation of the Mosaic Law, which renders profound implications. While both emphasize the inherent nature of all things, they diverge on the ultimate goal of knowledge in terms of the hierarchy of virtues. Along with Aristotle, Maimonides prioritizes rational virtue over moral virtue, thereby placing intellectual perfection as the ultimate human perfection. In contrast, Zhu Xi esteems knowledge of nature as facilitating the pursuit of the highest goal of sagehood, and leaves no room for the higher status of theoretical pursuit to moral cultivation. (shrink)

Direct download(4 more)   Export citation   Bookmark  

Size perception of visual objects is highly context dependent. Here we report a novel perceptual size illusion that the self-face, being a unique and distinctive self-referential stimulus, can enlarge its perceived size. By using a size discrimination paradigm, we found that the self-face was perceived as significantly larger than the other-face of the same size. This size overestimation effect was not due to the familiarity of the self-face, since it could be still observed when the self-face was directly compared with (...) a famous face. More crucially, such illusion effect could be extended to a new cartoon face that was transiently associated with one's own face and could also exert further contextual influences on visual size perception of other objects. These findings together highlight the role of self-awareness in visual size perception and point to a special mechanism of size perception tuned to self-referential information. (shrink)

Direct download(2 more)   Export citation   Bookmark   1 citation  

Background: Independent decision-making is one of the basic rights of patients. However, in clinical practice, most older cancer patients’ treatment decisions are made by family members. Objective: This study attempted to analyze the treatment decision-making process and formation mechanism for older cancer patients within the special cultural context of Chinese medical practice. Method: A qualitative study was conducted. With the sample saturation principle, data collected by in-depth interviews with 17 family members and 12 patients were subjected to thematic analysis. Ethical (...) considerations: The study was approved by the ethics committees of Sun Yat-sen University. All participants provided verbal informed consent after being told their rights of confidentiality, anonymity, and voluntary participation. They had the right to refuse to answer questions and could withdraw at any time. Results: Three themes emerged: (1) complex process; (2) transformation of family decision-making power; and (3) individual compromise. Family members inevitably had different opinions during the long process of treatment decision-making for older cancer patients. The direction of this process could be regarded as an extension of the family power relationship. The patient usually compromised the decision to survive, which was made by family members. Conclusion: This study describes the treatment decision-making process of older cancer patients in the context of Chinese culture. The reasons underlying this process are related to the views on life and death and family values. An individual is a part of the family, which is often seen as the minimal interpersonal unit in Chinese society. It is significant that while emphasizing patient autonomy in the decision-making process, health professionals should also pay attention to the important roles of culture and family. (shrink)

Direct download(2 more)   Export citation   Bookmark   1 citation  

There are differences in caregivers’ literacy and health literacy levels that may affect their ability to consent to children participating in clinical research trials. This study aimed to explore the effectiveness, and caregivers’ understandings, of the process of informed consent that accompanied their child’s participation in a dental randomized control trial (RCT). Telephone interviews were conducted with a convenience sample of ten caregivers who each had a child participating in the RCT. Pre-tested closed and open-ended questions were used, and the (...) findings were produced from an inductive analysis of the latter and a descriptive analysis of the former. Participants had limited understanding of the purpose of the RCT and rated the readability of the consent form more highly than they rated their understanding of the research. All felt that informed consent was vital, but some caregivers had not read the consent documents. Some caregivers enrolled their child in the RCT because they trusted the researchers, and the majority wanted to improve dental care for children. The informed consent process was not always effective despite high readability of the informed consent documents. Researchers must consider the health literacy of the study group, and actively engaging with caregivers to achieve meaningful informed consent may be challenging. Future research could explore participants’ perspectives of informed consent in populations with low health literacy and assess whether an underlying expectation not to comprehend health-related information may be a barrier to informed consent. (shrink)

Direct download(3 more)   Export citation   Bookmark   1 citation  

As of the end of October 2020, the cumulative number of confirmed cases of COVID-19 has exceeded 45 million and the cumulative number of deaths has exceeded 1.1 million all over the world. Faced with the fatal pandemic, countries around the world have taken various prevention and control measures. One of the important issues in epidemic prevention and control is the assessment of the prevention and control effectiveness. Changes in the time series of daily new confirmed cases can reflect the (...) impact of policies in certain regions. In this paper, a smooth transition autoregressive model is applied to investigate the intrinsic changes during the epidemic in certain countries and regions. In order to quantitatively evaluate the influence of the epidemic control measures, the sequence is fitted to the STAR model; then, comparisons between the dates of transition points and those of releasing certain policies are applied. Our model well fits the data. Moreover, the nonlinear smooth function within the STAR model reveals that the implementation of prevention and control policies is effective in some regions with different speeds. However, the ineffectiveness is also revealed and the threat of a second wave had already emerged. (shrink)

No categories

Direct download(2 more)   Export citation   Bookmark   1 citation  

In view of the fact that vigorously promoting recycling has become a viable means to promote sustainable development, it is important to better understand the impact of recycling efforts on subsequent resource saving behavior. This research empirically examines the effects of recycling efforts on subsequent resource saving by analyzing the survey data of 356 college students in China. The recycling efforts, environmental self-identity and feeling of pride were measured using existing scales while saving behaviors and recycling cost were measured by (...) developing new scales. Partial least squares structural equation modeling was performed to test the structural relationships among recycling efforts, environmental self-identity, feeling of pride, and saving behaviors. Further, the moderation role of recycling cost was tested. The results showed that saving behaviors could be classified into two types based on their costliness; recycling efforts have a positive effect on costless saving behaviors, while having a negative effect on costly saving behaviors; both the positive and negative effect of recycling efforts on resource saving is mediated by pride feeling and environmental self-identity; and recycling cost negatively moderates the effects of recycling efforts on pride feeling. We discuss the theoretical and managerial implications of the findings. (shrink)

Direct download(2 more)   Export citation   Bookmark   1 citation  

Previous research has shown that parenting style is intricately linked to cyber-aggression. However, the underlying mechanisms of this relationship remain unclear, especially among young adults. Guided by the social cognitive theory and the ecological system theory, this study aimed to examine the effect of parenting style on cyber-aggression, the potential mediating role of moral disengagement, and the moderating role of moral identity in this relationship. Participants comprised 1,796 Chinese college students who anonymously completed questionnaires on parenting style, moral disengagement, moral (...) identity, cyber-aggression, and demographic variables. After controlling for sex and age, parental rejection and over-protection were positively related to cyber-aggression; however, parental emotional warmth was non-significantly related to cyber-aggression. Mediation analysis revealed that parenting style was related to cyber-aggressive behavior through moral disengagement. Moderated mediation analysis further indicated that the indirect effect of parenting style on cyber-aggression was much stronger in college students with higher moral identity. The study carries important practical implications for parents and educators concerned about the destructive consequences of cyber-aggression. (shrink)

Direct download(2 more)   Export citation   Bookmark   1 citation  

Direct download(5 more)   Export citation   Bookmark   2 citations  

Direct download(2 more)   Export citation   Bookmark   2 citations  

We consider the possible cardinalities of the following three cardinal invariants which are related to the permutation group on the set of natural numbers: the least cardinal number of maximal cofinitary permutation groups; the least cardinal number of maximal almost disjoint permutation families; the cofinality of the permutation group on the set of natural numbers.We show that it is consistent with that ; in fact we show that in the Miller model.

Direct download(4 more)   Export citation   Bookmark   4 citations  

Direct download(2 more)   Export citation   Bookmark   1 citation  

Direct download(2 more)   Export citation   Bookmark   1 citation  

Previous studies have reported abnormal amplitude of low-frequency fluctuation and regional homogeneity in patients with migraine without aura using resting-state functional magnetic resonance imaging. However, how whole brain functional connectivity pattern homogeneity and its corresponding functional connectivity changes in patients with migraine without aura is unknown. In the current study, we employed a recently developed whole brain functional connectivity homogeneity method to identify the voxel-wise changes of functional connectivity patterns in 21 patients with migraine without aura and 21 gender and (...) age matched healthy controls. Moreover, resting-state functional connectivity analysis was used to reveal the changes of corresponding functional connectivities. FcHo analyses identified significantly decreased FcHo values in the posterior cingulate cortex, thalamus, and left anterior insula in patients with migraine without aura compared to healthy controls. Functional connectivity analyses further found decreased functional connectivities between PCC and medial prefrontal cortex, between AI and anterior cingulate cortex, and between THA and left precentral gyrus. The functional connectivities between THA and PCG were negatively correlated with pain intensity. Our findings indicated that whole brain FcHo and connectivity abnormalities of these regions may be associated with functional impairments in pain processing in patients with migraine without aura. (shrink)

Direct download(2 more)   Export citation   Bookmark   1 citation  

Direct download(2 more)   Export citation   Bookmark   1 citation  

Many previous studies have documented the detrimental effects of social loafing on others (_inter_personal impacts) at the between-person level. However, social loafing may carry underappreciated _intra_personal functional effects at the within-person level. Our research develops a novel theoretical framework to investigate _when_ and _how_ engaging in social loafing enhances one’s job performance. Drawing on the effort-recovery model and moral cleansing theory, we propose that social loafing may improve subsequent job performance by enhancing recovery and guilt. Specifically, we argue that among (...) employees who experience higher job demands or have higher moral identity, social loafing in the morning enhances their job performance in the afternoon by facilitating recovery or guilt in the morning. Two-wave daily data collected across ten consecutive workdays using the experience sampling method (ESM) supports this model. We discuss how this research identifies a functional basis for social loafing and provides implications for research and practice. (shrink)

Direct download(3 more)   Export citation   Bookmark  

Direct download(2 more)   Export citation   Bookmark   1 citation  

No categories

Direct download(2 more)   Export citation   Bookmark   1 citation  

This study aims to reveal the nature and motivation of human cooperation. By adopting the public goods game paradigm of competition and repetition, and introducing factors such as punishment and heterogeneous contributions, an experiment was conducted at Nanjing University in China, where 224 undergraduate students participated in seven games, including intragroup and intergroup competition. Meanwhile, participants’ social value orientation (SVO) was measured. The results indicated that cooperation (non-zero contribution) was the common choice for participants, but their contributions varied across rounds (...) and games. Individuals generally act as conditional free-riders in intragroup competition games, i.e., they use the “small for big” strategy. In contrast, individuals generally act as conditional cooperators in intergroup competitive games, i.e., they use the “tit for tat” strategy. Although SVO should theoretically be related to contribution, analysis revealed that participants’ contributions were not significantly dominated by SVO, but were primarily driven by self-interest. Specifically, individuals switch back and forth between conditional cooperators and conditional free-riders to seek maximum self-interest. Our results not only reveal the complexity and strategic nature of human behavior in competitive contexts but also highlight the central role of self-interest in driving individual decision-making, reflecting the balance between individuals’ pursuit of self-interest and adaptation to the environment in social interactions. (shrink)

No categories

Direct download(4 more)   Export citation   Bookmark  

We discuss a problem asked by E. van Douwen and A. Miller [5] in various forcing models.

Direct download   Export citation   Bookmark   3 citations  

No categories

Direct download(2 more)   Export citation   Bookmark   1 citation  

No categories

Direct download(2 more)   Export citation   Bookmark   1 citation  

No categories

Direct download(3 more)   Export citation   Bookmark   1 citation  

No categories

Direct download(3 more)   Export citation   Bookmark   1 citation  

The autophagy initiation complex is brought about via a highly ordered and stepwise assembly process. Two crucial signaling molecules, mTORC1 and AMPK, orchestrate this assembly by phosphorylating/dephosphorylating autophagy‐related proteins. Activation of Atg1 followed by recruitment of both Atg9 vesicles and the PI3K complex I to the PAS (phagophore assembly site) are particularly crucial steps in its formation. Ypt1, a small Rab GTPase in yeast cells, also plays an essential role in the formation of the autophagy initiation complex through multiple regulatory (...) pathways. In this review, our primary focus is to discuss how signaling molecules initiate the assembly of the autophagy initiation complex, and highlight the significant roles of Ypt1 in this process. We end by addressing issues that need future clarification. (shrink)

Direct download(2 more)   Export citation   Bookmark