Responsive Neurostimulation Targeting the Anterior, Centromedian and Pulvinar Thalamic Nuclei and the Detection of Electrographic Seizures in Pediatric and Young Adult Patients.Cameron P. Beaudreault,Carrie R. Muh,Alexandria Naftchi,Eris Spirollari,Ankita Das,Sima Vazquez,Vishad V.Sukul,Philip J. Overby,Michael E. Tobias,Patricia E. McGoldrick &Steven M. Wolf -2022 -Frontiers in Human Neuroscience 16.detailsBackgroundResponsive neurostimulation has been utilized as a treatment for intractable epilepsy. The RNS System delivers stimulation in response to detected abnormal activity, via leads covering the seizure foci, in response to detections of predefined epileptiform activity with the goal of decreasing seizure frequency and severity. While thalamic leads are often implanted in combination with cortical strip leads, implantation and stimulation with bilateral thalamic leads alone is less common, and the ability to detect electrographic seizures using RNS System thalamic leads is (...) uncertain.ObjectiveThe present study retrospectively evaluated fourteen patients with RNS System depth leads implanted in the thalamus, with or without concomitant implantation of cortical strip leads, to determine the ability to detect electrographic seizures in the thalamus. Detailed patient presentations and lead trajectories were reviewed alongside electroencephalographic analyses.ResultsAnterior nucleus thalamic leads, whether bilateral or unilateral and combined with a cortical strip lead, successfully detected and terminated epileptiform activity, as demonstrated by Cases 2 and 3. Similarly, bilateral centromedian thalamic leads or a combination of one centromedian thalamic alongside a cortical strip lead also demonstrated the ability to detect electrographic seizures as seen in Cases 6 and 9. Bilateral pulvinar leads likewise produced reliable seizure detection in Patient 14. Detections of electrographic seizures in thalamic nuclei did not appear to be affected by whether the patient was pediatric or adult at the time of RNS System implantation. Sole thalamic leads paralleled the combination of thalamic and cortical strip leads in terms of preventing the propagation of electrographic seizures.ConclusionThalamic nuclei present a promising target for detection and stimulation via the RNS System for seizures with multifocal or generalized onsets. These areas provide a modifiable, reversible therapeutic option for patients who are not candidates for surgical resection or ablation. (shrink)
Agricultural extension in sub-Saharan Africa: Extension typologies and issues for the future.V. Venkatesan -1997 -Knowledge, Technology & Policy 9 (4):43-61.detailsEver since the extension systems based on Training and Visit (T&V) were started, first in Asia, and since 1981 in sub-Saharan Africa, there have been many writings about T&V. This article gives the various extension typologies possible, and places T&V in a broader perspective. The main message of the article is that the international institutions, donors and academia would, instead of spending their time and energy discussing what are essentially nonissues, serve the countries in the region much better by focusing (...) on areas where improvements should be made to their extension systems in order to enable them to tackle the future issues. (shrink)
Razmyshlenii︠a︡ naturalista.V. I. Vernadskiĭ -1975 - Moskva: Nauka. Edited by Bonifatiĭ Mikhaĭlovich Kedrov.details[kn. 1] Prostranstvo i vremi︠a︡ v nezhivoĭ i zhivoĭ prirode --kn. 2. Nauchnai︠a︡ myslʹ kak planetnoe i︠a︡vlenie.
On the Design of the BookIntroduction to Philosophy [Vvedenie v Filosofiiu].I. T. Frolov,V. S. Stepin,V. A. Lektorskii &V. Zh Kelle -1990 -Russian Studies in Philosophy 28 (4):25-57.detailsA large team of well-known Soviet scholars is currently preparing a new textbook in philosophy. We thought it might be useful to acquaint the broad philosophical public with the ideas that guided the authors in writing the textbook, and have included its table of contents, preface, and conclusion. We also, together with the team of authors, are hoping for readers' responses. The book will be published shortly by Politizdat Publishers.
No categories
Vladimir alexandrovich Smirnov as a founder of research schools in logic and methodology of science in the USSR and russia.V. K. Finn -2000 -Studia Logica 66 (2):205-213.detailsThe article gives a short account of V.A. Smirnovs scientific biography, including his work in Tomsk University in Siberia and in the Department of Logic of the Institute of Philosophy in Moscow.
Dialogs of a hybrid world.V. V. Chekletsov -forthcoming -Philosophical Problems of IT and Cyberspace.detailsThe article is based on reports and discussions held during three online events organized by the Russian Research Center for the Internet of Things together with the Department of Philosophy and Sociology of South-West State University during 2021: an open discussion with the famous transhumanist philosopher David Pearce dedicated to the birthday of Jeremiah Bentham on February 15, a round table dedicated to the World Internet of Things Day on April 9, and a session within the first IoT Hot Spots (...) conference on June 16. The main topics for discussion this year were the consideration of the following philosophical and socio-cultural problems and concepts in the light of the development of cyberphysical systems: anthropological differences between the «posthuman» and «metahuman» projects, epistemological aspects of bio- and cybersemiotics in modern hybrid techno-social networks, the cultural dimension of remote proximity in the digital age, the ontology of the quantum complexity of the digital multiverse, the ethical dimensions of the digital economy in the post-covid period, the aesthetics of metamodernism in the smart city, the anthropocene effects of silicon addiction and the race of computing, socio-philosophical problems of management in situations of high uncertainty, political strategies for sustainable development. (shrink)
No categories
Kenosistizm, as a characteristic feature of the religious doctrine of the great white fraternity.V. Grynko -1998 -Ukrainian Religious Studies 7:174-177.detailsThe complicated process of the formation of post-Soviet countries has created favorable conditions for the development of various neoregliginiph cultures, the majority of which have become widespread mainly due to the activity of foreign missionaries. Therefore, the phenomenon of the "Great White Brotherhood" founded by Kyivan Y. Krivonogov, whose activities had a significant social resonance in Ukraine and abroad, is of particular importance.
No categories
The Socializing Role of the Socialist Principle of Distribution.V. I. Zagorodnii -1976 -Russian Studies in Philosophy 15 (1):33-35.detailsThe institution of the principle of distribution in accordance with work performed in the process of the building of socialism and the consistent implementation of this principle under the conditions of developed socialism are powerful factors in the establishment and consistent implementation of the principle of the universality of work. In the course of the building of communism, payment in accordance with work done will remain the principal source of growth of incomes. Therefore, the completeness of satisfaction of people's requirements (...) and their prosperity depend predominantly on the amount and quality of the work given to society. However, a high level of communist consciousness presumes not merely participation in social labor but a perceived need to work as efficiently and productively as possible. (shrink)
Teorii︠a︡ izobrazitelʹnogo iskusstva.V. I. Zhukovskiĭ -2011 - Sankt-Peterburg: Aleteĭi︠a︡.detailsZhiznennai︠a︡ neobkhodimostʹ obshchenii︠a︡ cheloveka s proizvedenii︠a︡mi iskusstva -- Prot︠s︡ess proizvodstva proizvedenii︠a︡ iskusstva -- Prot︠s︡edura potreblenii︠a︡ proizvedenii︠a︡ iskusstva -- Sistema proizvedeniĭ iskusstva -- Kompozit︠s︡irovanie i kompozit︠s︡ii khudozhestvennogo obraza -- Iskusstvoved-professional kak nositelʹ kont︠s︡eptualʹnogo znanii︠a︡ o sfere izobrazitelʹnogo iskusstva.
Export citation
Bookmark
Istoki i razvitie ėkologicheskoĭ kulʹtury, ėtiki i ėstetiki: kollektivnai︠a︡ monografii︠a︡.V. A. Zimin (ed.) -2011 - Samara: Izd-vo "As Gard".detailsДля широкого круга читателей (слушателей, аспирантов, преподавателей) интересующихся данной проблемой.
The neo-Marxist idea of socialism and Christianity.V. V. Zinchenko -2000 -Ukrainian Religious Studies 16:11-22.detailsAlong with other definitions, the XX century is also called a century of domination of ideologies, which almost always considered a person as a means to establish one or another type of domination: either national, or class, or bureaucratic. Any but mandatory one that would resist human freedom, and therefore - justice. Ideology exits a person to think freely and make informed decisions. She wants to accustom her to adapt humbly to the existing political and economic conditions, to form a (...) superficial perception of the propagandized reality of the best and the unchangeable. The ideology of totalitarianism seeks to turn a person into a "social dream," self-sacrificed, and a satisfied citizen of every kind, indifferent to spiritual demands. (shrink)
No categories