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Results for 'Suzanne M. Adlof'

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  1.  40
    Structured narrative retell instruction for young children from low socioeconomic backgrounds: a preliminary study of feasibility.Suzanne M.Adlof,Angela N. McLeod &Brianne Leftwich -2014 -Frontiers in Psychology 5.
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  2.  71
    Modernizing Research Regulations Is Not Enough: It's Time to Think Outside the Regulatory Box.Suzanne M. Rivera,Kyle B. Brothers,R. Jean Cadigan,Heather L. Harrell,Mark A. Rothstein,Richard R. Sharp &Aaron J. Goldenberg -2017 -American Journal of Bioethics 17 (7):1-3.
  3. The Human Deviation from Natural Logic in the" apologie de raimond sebond.Suzanne M. Verderber -2007 - In Corinne Noirot-Maguire & Valérie M. Dionne,Revelations of character: ethos, rhetoric, and moral philosophy in Montaigne. Newcastle, U.K.: Cambridge Scholars Press. pp. 201.
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  4.  55
    Teaching health care ethics: the importance of moral sensitivity for moral reasoning.Suzanne M. Jaeger -2001 -Nursing Philosophy 2 (2):131-142.
  5.  26
    Teaching health care ethics: The importance of moral sensitivity for moral reasoning.Suzanne M. Jaeger PhD -2001 -Nursing Philosophy 2 (2):131–142.
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  6.  53
    Routine Computing Tasks: Planning as Understanding.Suzanne M. Mannes &Walter Kintsch -1991 -Cognitive Science 15 (3):305-342.
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  7.  68
    The impact of psychological factors on placebo responses in a randomized controlled trial comparing sham device to dummy pill.Suzanne M. Bertisch,Anna R. T. Legedza,Russell S. Phillips,Roger B. Davis,William B. Stason,Rose H. Goldman &Ted J. Kaptchuk -2009 -Journal of Evaluation in Clinical Practice 15 (1):14-19.
  8.  82
    Ethical reasoning and the embodied, socially situated subject.Suzanne M. Jaeger -2004 -Theoretical Medicine and Bioethics 26 (1):55-72.
    My discussion is concerned with how symbolic power constitutively structures our very identities in relation to one another and at the bodily level of lived experience. Although many accounts of the self and of subjectivity as socially situated have difficulties in their explanations of agency, Zaners work suggests a basis upon which the selfs independence from others can be understood. His phenomenology of embodied subjectivity explains how the emerging self presupposes presence with others. At the same time, however, co-presence also (...) reveals the selfs distinct perspective and capacity for circumstantial possibilizing, that is to say, actualizing another possible than the actual. My aim is to examine critically the intersections between Zaners phenomenology and other theoretical accounts of the socially situated self. I also show how Zaners work contributes to these discussions a way of understanding the possibility of agency that is rooted in embodied experience. (shrink)
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  9.  218
    World Traveling as a Clinical Methodology for Psychiatric Care.Suzanne M. Jaeger -2003 -Philosophy, Psychiatry, and Psychology 10 (3):227-231.
    In lieu of an abstract, here is a brief excerpt of the content:Philosophy, Psychiatry, & Psychology 10.3 (2003) 227-231 [Access article in PDF] World Traveling as a Clinical Methodology for Psychiatric CareSuzanne M. Jaeger Keywords embodiment, dialogical consciousness, interpersonal communication, epistemic responsibility, self-knowledge, understanding IN HER ARTICLE "Moral Tourists and World Travelers," Nancy Potter suggests a way in which psychiatrists and psychologists could gain a better understanding of their mentally ill patients' experiences. Rather than assuming that hallucinations and (...) incoherent speech and behavior are merely senseless disconnections from reality, Potter argues that mental health care clinicians ought to spend time engaging patients on their own terms. Even when mental illness is a result of brain disease, much can be learned about the patient's experiences of their disease by temporarily setting aside the scientific frameworks of diagnosis and medical treatment. Potter uses Maria Lugones' concept of world traveling and recommends playfully accepting, and even entering into the patient's world (Lugones 1990). She calls world traveling a methodology and explains it in some detail. Moreover, at the close of her essay, Potter suggests that clinicians have a moral obligation to understand the mentally ill patient's world from the patient's perspective. This obligation is based on an appeal to our sense of what it is to be a responsible knower who attends to issues of trust and truth. Relying on arguments made by Lorraine Code (1987), Potter asserts that to try to understand the other's perspective is the responsible thing to do.My discussion focuses on the notion of play to which Potter appeals, as well as on what she sees as the moral obligation of clinicians to communicate with their mentally ill patients in extra-professional ways. This moral obligation arises because (a) the theoretical and professional frameworks of medical science are seen as inadequate, and (b) playfulness opens up mutually respectful, authentic interaction between persons. I generally agree with Potter's claims, and I want to situate them in the wider framework of an epistemological debate about the status of our knowledge of others. A broader context will help to elucidate the strengths of Potter's analysis as well as some points for critical discussion. I begin with the relationship of trust between clinicians and patients.Few people would disagree with the claim that patients need to be able to trust that their physicians are not harming them, but helping them to get better. If patients feel misunderstood, they will not trust their caretakers. This is probably even truer for psychiatric patients, whose conditions and loss of autonomy make establishing trust even more challenging. Psychiatric patients [End Page 227] often have their own ways of compensating for the symptoms of their mental illness. If either their will to survive or their compensatory strategies go unrecognized or misinterpreted, patients may respond by rejecting the well-intentioned efforts of caretakers to restore them to a degree of ease, measured as it must be by the standards of the professionals under whose care the patient remains. 1 Despite the fact that these standards are established through scientific testing procedures for the treatment of diseases, they may be experienced by patients as indifferent to the particular and unique features of their condition. Nestled within the issue of trust is thus a question of truth.Although current scientific knowledge of the human brain, and of human behavior, has made available a range of sophisticated therapies and psychotropic drugs, there are still many mental illnesses that leave families and clinicians wondering whether the treatment plans are providing any help. Alzheimer's disease and schizophrenia are two examples. There is a difference between, on the one hand, containing the patient's behavior by admitting the patient to a psychiatric ward and managing symptoms with psychotropic medications, and, on the other hand, understanding what is happening for the patient, from his or her perspective. Although psychiatric patients may not have a realistic sense of either their abilities or the extent and nature of their disease, there may be much about their experiences that ought to be known and understood by the professionals caring for them... (shrink)
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  10.  26
    Altmesopotamische Weihplatten.Suzanne M. Pelzel &Johannes Boese -1977 -Journal of the American Oriental Society 97 (1):67.
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  11.  16
    The Case Manager’s View.Suzanne M. Burke -2006 -Journal of Clinical Ethics 17 (1):83-84.
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  12.  16
    Is Culture Important to the Relationship Between Quality of Life and Resilience? Global Implications for Preparing Communities for Environmental and Health Disasters.Suzanne M. Skevington -2020 -Frontiers in Psychology 11.
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  13.  20
    Identity by Design: Some Epistemological and Control Issues.Suzanne M. Jaeger -2003 -Philosophy of Education 59:129-131.
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  14.  81
    The Body as a Permanent but Mutable Address.Suzanne M. Jaeger -2006 -Human Studies 29 (1):129-134.
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  15.  29
    Legal Notes: Is There a Place for Lawyers on Ethics Committees? A View from the Inside.Suzanne M. Mitchell &Martha S. Swartz -1990 -Hastings Center Report 20 (2):32.
  16.  98
    Hildegard and Holism.Suzanne M. Phillips &Monique D. Boivin -2007 -Philosophy, Psychiatry, and Psychology 14 (4):377-379.
    In lieu of an abstract, here is a brief excerpt of the content:Hildegard and HolismSuzanne M. Phillips (bio) and Monique D. Boivin (bio)Keywordsbiopsychosocial, integration, medieval, mental illnessWe appreciate the careful and enriching commentary offered by Kroll and by Radden on our paper about holistic views of mental illness in the writings of the twelfth-century abbess and healer Hildegard of Bingen. Both reviewers are well-established figures in the study of historical perspectives on mental illness, an area that we have just begun (...) to explore. We are glad for the opportunity to respond to their observations and thereby to continue the dialogue.First, we would like to clarify our purpose in preparing this paper. Nowhere do we claim that Hildegard used a biopsychosocial model of mental illness, either in addressing the needs of the particular case of Sigewiza, or more generally in her writings on illness and health. In fact, we agree with Kroll (2007, 370), when he states that Hildegard did not use a biopsychosocial model. We use the term “biopsychosocial” only three times in the paper, always by contrast with what we see in Hildegard’s writings. The present-day biopsychosocial model focuses on getting a range of perspectives on the table, encouraging the consideration of biological, psychological, and social issues when thinking about mental illness. This is a good thing, but we argue that it does not go far enough. Specifically, there has been insufficient attention to ways these perspectives might interact.How, then, might we describe Hildegard’s way of conceptualizing mental illness? In place of the label “biopsychosocial model,” Kroll suggests that Hildegard’s approach could be described as a “religious model” (p. 372). Here we disagree. By our reading, Hildegard’s description of mental illness involves religious components, certainly, but also humoral, astrological, interpersonal, community, and intrapsychic components. Radden correctly notes that we are not so much interested in the particular components as we are in their interactions. We are attracted to Hildegard’s writings because she attends to these interactions. Our students, like Kroll’s (p. 371), are curious about mind–body relationships, which represent one example of the interplay between components. Our concern is that the current biopsychosocial model often fails to satisfy our own, and our students’, interest in the nature of those interactions. Our hope is that Hildegard’s writings might help us to think more richly about the interactions.As Radden (2007, 373) points out, present-day psychiatrists and psychologists do in fact use mul-ticausal accounts of depression. And we agree that such accounts need not be reductionistic (Kroll, 371). But we also recognize that psychology and psychiatry have well-established reductionist (more specifically, materialist) habits. To borrow [End Page 377] Kroll’s phrase, the biological model threatens “to swallow all other models” (p. 371). We must guard against such reductionism, given the habits of our disciplines. As we noted, McHugh and Slavney (1998) respond to that threat by building walls between the perspectives, suggesting that we might use different perspectives when thinking about different sorts of problems. We think that there ought to be more synthetic, holistic ways of responding to that threat, and we are hopeful that Hildegard’s writings can help us to develop those.At a basic level, we see Hildegard asking different questions than people ask today. On the first page of his commentary, for example, Kroll poses the question of “which of these three modalities [bio-, psycho-, social] may be sufficient” (p. 369) in the particular medieval text. We found that the sufficiency of one modality or another does not concern Hildegard. We are not able to speak to the general point that Kroll raises, that one or another element is emphasized depending on the goal of the medieval text; we can report our experience in reading Hildegard, where we found no sense in which one or another component is privileged. Even though Hildegard operated within a thoroughly religious context, we did not find examples of her subsuming other factors under religion. Everything interacts with spiritual concerns, to be sure, but everything also interacts with the biological, and with the interpersonal, and with the astrological. Although it may seem odd to us post-Darwinian thinkers, Hildegard’s model is essentially... (shrink)
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  17.  144
    Responsibility and obligation: Some Kantian directions.Suzanne M. Uniacke -2005 -International Journal of Philosophical Studies 13 (4):461 – 475.
    This paper asks how we should conceptualize the relationship between responsibility and obligation. Its central concern is the relevance of considerations of obligation to the attribution of responsibility for what we do or bring about. The paper approaches this issue through an examination of Kant's complex, challenging and instructive theory of responsibility, in which strict obligation plays a pivotal role in attributions of responsibility for the outcomes of our actions. Even if we do not accept Kant's strongly juridical concept of (...) responsibility, his theory provides insight into the way in which we should see the connection between responsibility and obligation. (shrink)
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  18.  10
    The PSDA: A Long-Term Care View.Suzanne M. Weiss -1991 -Journal of Clinical Ethics 2 (3):196-199.
  19.  45
    (1 other version)The Doctrine of Double Effect.Suzanne M. Uniacke -1984 -The Thomist 48 (2):188-218.
  20. Language and Intersubjectivity in the Phenomenology of Edmund Husserl.Suzanne M. Cunningham -1972 - Dissertation, The Florida State University
  21.  32
    A Belmont Reboot: Building a Normative Foundation for Human Research in the 21st Century.Kyle B. Brothers,Suzanne M. Rivera,R. Jean Cadigan,Richard R. Sharp &Aaron J. Goldenberg -2019 -Journal of Law, Medicine and Ethics 47 (1):165-172.
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  22.  40
    Willard, Frances and the feminism of fear.Suzanne M. Marilley -1993 -Feminist Studies 19 (1):123-146.
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  23.  19
    13. Labor organization and the quality of life in the American states.Suzanne M. Coshow &Benjamin Radcliff -2009 - In Amitava Krishna Dutt & Benjamin Radcliff,Happiness, Economics and Politics: Towards a Multi-Disciplinary Approach. Edward Elgar. pp. 285.
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  24.  52
    Essays on Aesthetic Genesis.Suzanne M. Jaeger -2018 -The European Legacy 23 (1-2):195-198.
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  25.  126
    Medieval Holism: Hildegard of Bingen on Mental Disorder.Suzanne M. Phillips &Monique D. Boivin -2007 -Philosophy, Psychiatry, and Psychology 14 (4):359-368.
    Current efforts to think holistically about mental disorder may be assisted by considering the integrative strategies used by Hildegard of Bingen, a twelfth-century abbess and healer. We search for integrative strategies in the detailed records of Hilde-gard’s treatment of the noblewoman Sigewiza and in Hildegard’s more general writings. Three strategies support Hildegard’s holistic thinking: the use of narrative approaches to mental illness, acknowledging interdependence between perspectives, and applying principles of balance to the relationships between perspectives. Applying these three strategies to (...) the present-day conceptualization and treatment of mental disorder could move us toward a more thoroughly integrated understanding of the field. (shrink)
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  26.  63
    The ceo's influence on corporate foundation giving.James D. Werbel &Suzanne M. Carter -2002 -Journal of Business Ethics 40 (1):47 - 60.
    Some scholars have argued that CEOs may have excessive influence on their foundation's trustees to give away a portion of company profits to charitable causes in order to gain access to elite circles or support the CEO's personal causes. This may result in charitable contributions that ultimately serve the personal interests of the CEOs without regard to corporate interests or social needs. We examine the extent that CEOs appear to direct charitable giving to be compatible with their own personal interests, (...) and if CEO participation on the foundation board affects the relationship between CEO personal interests and charitable giving. Using a sample of 160 corporate foundations, our results showed that CEOs' interests, as measured by membership in different non-profit organizations, was associated with foundation charitable giving. This association decreased, but was not eliminated, when CEOs were absent from the foundation board. Implications of these findings for researchers and managers are discussed in regards to both agency theory and stewardship theory. (shrink)
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  27.  51
    "Existentialism and Creativity," by Mitchell Bedford. [REVIEW]Suzanne M. Cunningham -1975 -Modern Schoolman 52 (4):436-438.
  28.  78
    The effect of controllability and causality on counterfactual thinking.Caren A. Frosch,Suzanne M. Egan &Emily N. Hancock -2015 -Thinking and Reasoning 21 (3):317-340.
    Previous research on counterfactual thoughts about prevention suggests that people tend to focus on enabling rather than causing events and controllable rather than uncontrollable events. Two experiments explore whether counterfactual thinking about enablers is distinct from counterfactual thinking about controllable events. We presented participants with scenarios in which a cause and an enabler contributed to a negative outcome. We systematically manipulated the controllability of the cause and the enabler and asked participants to generate counterfactuals. The results indicate that when only (...) the cause or the enabler is controllable participants undid the controllable event more often. However, when the cause and enabler are matched in controllability participants undid the enabler slightly more often. The findings are discussed in the context of the mental model, functional and judgement dissociation theories as well as previous research on counterfactual thinking. The importance of controllability and.. (shrink)
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  29.  28
    Unstable Networks Among Women in Academe: The Legal Case of Shyamala Rajender.Sally G. Kohlstedt &Suzanne M. Fischer -2009 -Centaurus 51 (1):37-62.
    Scientific networks are often credited with bringing about institutional change and professional advancement, but less attention has been paid to their instability and occasional failures. In the 1970s optimism among academic women was high as changing US policies on sex discrimination in the workplace, including higher education, seemed to promise equity. Encouraged by colleagues, Shyamala Rajender charged the University of Minnesota with sex discrimination when it failed to consider her for a tenure-track position. The widely cited case of this chemist (...) was not, however, settled easily and involved nearly a decade of university grievance procedures and litigation that grew to a class action lawsuit. As the case gained national attention and internal resistance stiffened, the clusters of women who had been encouraging flickered, faded and sometimes regrouped. A negotiated settlement (consent decree) ended Rajender’s case, and it opened the door for hundreds of others to present their grievances regarding gender discrimination. Networks and support groups proved important but also unstable for individuals who sought equity before and during the implementation of the decree. The Rajender case thus exposes the painful, balky and inevitably contentious process of fighting discrimination. It also demonstrates the power and limits of institutions and litigation, as well as the possibilities and disappointments of informal and formal women’s networks. (shrink)
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  30.  93
    Consenting to uncertainty: Challenges for informed consent to disease screening—a case study.Mark Greene &Suzanne M. Smith -2008 -Theoretical Medicine and Bioethics 29 (6):371-386.
    This paper uses chronic beryllium disease as a case study to explore some of the challenges for decision-making and some of the problems for obtaining meaningful informed consent when the interpretation of screening results is complicated by their probabilistic nature and is clouded by empirical uncertainty. Although avoidance of further beryllium exposure might seem prudent for any individual whose test results suggest heightened disease risk, we will argue that such a clinical precautionary approach is likely to be a mistake. Instead, (...) advice on the interpretation of screening results must focus not on risk per se, but on avoidable risk, and must be carefully tailored to the individual. These points are of importance for individual decision-making, for informed consent, and for occupational health. (shrink)
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  31.  40
    Business Versus Personal Values: Does a Double Standard Exist?Roger W. Bartlett &Suzanne M. Ogilby -1996 -Business and Professional Ethics Journal 15 (3):37-63.
  32.  14
    Toward a Minor Ethics.Casey Ford &Suzanne M. McCullagh -2021 - In Casey Ford, Suzanne McCullagh & Karen Houle,Minor ethics: Deleuzian variations. Chicago: McGill-Queen's University Press. pp. 3-30.
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  33.  40
    Beauty and the Breast: Dispelling Significations of Feminine Sensuality in the Aesthetics of Dance.Suzanne M. Jaeger -1997 -Philosophy Today 41 (2):270-276.
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  34.  15
    Historical and archaeological perspectives on gender transformations: from private to public.Suzanne M. Spencer-Wood (ed.) -2013 - New York: Springer.
    In many facets of Western culture, including archaeology, there remains a legacy of perceiving gender divisions as natural, innate, and biological in origin. This belief follows that men are naturally pre-disposed to public, intellectual pursuits, while women are innately designed to care for the home and take care of children. In the interpretation of material culture, accepted notions of gender roles are often applied to new findings: the dichotomy between the domestic sphere of women and the public sphere of men (...) can color interpretations of new materials. In this innovative volume, the contributors focus explicitly on analyzing the materiality of historic changes in the domestic sphere around the world. Combining a global scope with great temporal depth, chapters in the volume explore how gender ideologies, identities, relationships, power dynamics, and practices were materially changed in the past, thus showing how they could be changed in the future. (shrink)
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  35.  74
    Improving Informed Consent: The Medium Is Not the Message.Patricia Agre,Frances A. Campbell,Barbara D. Goldman,Maria L. Boccia,Nancy Kass,Laurence B. McCullough,Jon F. Merz,Suzanne M. Miller,Jim Mintz &Bruce Rapkin -2003 -IRB: Ethics & Human Research 25 (5):S11.
  36.  79
    IRB practices and policies regarding the secondary research use of biospecimens.Aaron J. Goldenberg,Karen J. Maschke,Steven Joffe,Jeffrey R. Botkin,Erin Rothwell,Thomas H. Murray,Rebecca Anderson,Nicole Deming,Beth F. Rosenthal &Suzanne M. Rivera -2015 -BMC Medical Ethics 16 (1):32.
    As sharing and secondary research use of biospecimens increases, IRBs and researchers face the challenge of protecting and respecting donors without comprehensive regulations addressing the human subject protection issues posed by biobanking. Variation in IRB biobanking policies about these issues has not been well documented.
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  37.  42
    Implicit memory for visual objects and the structural description system.Daniel L. Schacter,Lynn A. Cooper &Suzanne M. Delaney -1990 -Bulletin of the Psychonomic Society 28 (4):367-372.
  38.  46
    Broken barriers: Human-induced changes to gene flow and introgression in animals.Erika Crispo,Jean-Sébastien Moore,Julie A. Lee-Yaw,Suzanne M. Gray &Benjamin C. Haller -2011 -Bioessays 33 (7):508-518.
    We identify two processes by which humans increase genetic exchange among groups of individuals: by affecting the distribution of groups and dispersal patterns across a landscape, and by affecting interbreeding among sympatric or parapatric groups. Each of these processes might then have two different effects on biodiversity: changes in the number of taxa through merging or splitting of groups, and the extinction/extirpation of taxa through effects on fitness. We review the various ways in which humans are affecting genetic exchange, and (...) highlight the difficulties in predicting the impacts on biodiversity. Gene flow and hybridization are crucially important evolutionary forces influencing biodiversity. Humans alter natural patterns of genetic exchange in myriad ways, and these anthropogenic effects are likely to influence the genetic integrity of populations and species. We argue that taking a gene-centric view towards conservation will help resolve issues pertaining to conservation and management.Editor's suggested further reading in BioEssays A systemic view of biodiversity and its conservation: Processes, interrelationships, and human culture Abstract. (shrink)
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  39.  22
    Toward a Sociological Imagination: Bridging Specialized Fields.Bernard Phillips,Harold Kincaid,Thomas Scheff,Chanoch Jacobsen,James C. Kimberly,Richard Lachmann,David R. Maines,David W. Britt,Suzanne M. Retzinger,Thomas J. Scheff &Howard S. Becker -2002 - Upa.
    Toward A Sociological Imagination builds on the ideas C. Wright Mills expressed in The Sociological Imagination for an approach to the scientific method broad enough to open up to the full range of knowledge within the sociology discipline. In this book, nine sociologists and one philosopher provide detailed tests of the utility of the approach within diverse substantive sociological areas.
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  40.  35
    How Technology Features Influence Public Response to New Agrifood Technologies.Amber Ronteltap,Machiel J. Reinders,Suzanne M. Van Dijk,Sanne Heijting,Ivo A. Van der Lans &Lambertus A. P. Lotz -2016 -Journal of Agricultural and Environmental Ethics 29 (4):643-672.
    New agrifood technologies are often difficult to grasp for the public, which may lead to resistance or even rejection. Insight into which technology features determine public acceptability of the technology could offer guidelines for responsible technology development. This paper systematically assesses the relative importance of specific technology features for consumer response in the agrifood domain in two consecutive studies. Prominent technology features were selected from expert judgment and literature. The effects of these features on consumer evaluation were tested in a (...) consumer study. Fictitious technologies were used to avoid any uncontrollable contextual influences that existing new technologies may evoke. Results show that technologies that were seen as more natural and newer were perceived less risky, more beneficial, and were evaluated more positively. Technologies applied to food were judged to be more beneficial, but also more risky than those applied to non-food. Technologies used in the production process were perceived to be less risky and evaluated more positively than those used in the product. Technologies owned by the market leader were perceived to be more beneficial, and evaluated more positively than those that were freely available. In a next study, effects of the technology features on consumer response were tested for existing new agrifood technologies. This study replicated the results for perceived naturalness, perceived newness, and place in the production process where the technology is applied. However, in contrast to the first study, we did not find an effect of application area and technology ownership. (shrink)
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  41.  54
    Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.Vladimir Vacic,Shane McCarthy,Dheeraj Malhotra,Fiona Murray,Hsun-Hua Chou,Aine Peoples,Vladimir Makarov,Seungtai Yoon,Abhishek Bhandari,Roser Corominas,Lilia M. Iakoucheva,Olga Krastoshevsky,Verena Krause,Verónica Larach-Walters,David K. Welsh,David Craig,John R. Kelsoe,Elliot S. Gershon,Suzanne M. Leal,Marie Dell Aquila,Derek W. Morris,Michael Gill,Aiden Corvin,Paul A. Insel,Jon McClellan,Mary-Claire King,Maria Karayiorgou,Deborah L. Levy,Lynn E. DeLisi &Jonathan Sebat -unknown
    Rare copy number variants have a prominent role in the aetiology of schizophrenia and other neuropsychiatric disorders. Substantial risk for schizophrenia is conferred by large CNVs at several loci, including microdeletions at 1q21.1, 3q29, 15q13.3 and 22q11.2 and microduplication at 16p11.2. However, these CNVs collectively account for a small fraction of cases, and the relevant genes and neurobiological mechanisms are not well understood. Here we performed a large two-stage genome-wide scan of rare CNVs and report the significant association of copy (...) number gains at chromosome 7q36.3 with schizophrenia. Microduplications with variable breakpoints occurred within a 362-kilobase region and were detected in 29 of 8,290 patients versus 2 of 7,431 controls in the combined sample. All duplications overlapped or were located within 89 kilobases upstream of the vasoactive intestinal peptide receptor gene VIPR2. VIPR2 transcription and cyclic-AMP signalling were significantly increased in cultured lymphocytes from patients with microduplications of 7q36.3. These findings implicate altered vasoactive intestinal peptide signalling in the pathogenesis of schizophrenia and indicate the VPAC2 receptor as a potential target for the development of new antipsychotic drugs. © 2011 Macmillan Publishers Limited. All rights reserved. (shrink)
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  42. The Secret of Democracy.Suzanne Labin &Francis M. Myers -1956 -Ethics 67 (1):58-60.
  43.  34
    Maximization should sometimes lead to abstinence.Suzanne H. Mitchell &William M. Baum -1996 -Behavioral and Brain Sciences 19 (4):589-590.
    Heyman's model, paradoxically, predicts that whereas a maximizing approach to drug choice will prevent escalation of drug use it will never yield complete abstinence. We suggest an alternative model that overcomes this difficulty by focusing on changes in drug tolerance. A small modification allows maximization to predict either abstinence or moderation (e.g., social drinking).
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  44.  28
    Swallow Motor Pattern Is Modulated by Fixed or Stochastic Alterations in Afferent Feedback.Suzanne N. King,Tabitha Y. Shen,M. Nicholas Musselwhite,Alyssa Huff,Mitchell D. Reed,Ivan Poliacek,Dena R. Howland,Warren Dixon,Kendall F. Morris,Donald C. Bolser,Kimberly E. Iceman &Teresa Pitts -2020 -Frontiers in Human Neuroscience 14:511045.
    Afferent feedback can appreciably alter the pharyngeal phase of swallow. In order to measure the stability of the swallow motor pattern during several types of alterations in afferent feedback, we assessed swallow during a conventional water challenge in four anesthetized cats, and compared that to swallows induced by fixed (20 Hz) and stochastic (1-20Hz) electrical stimulation applied to the superior laryngeal nerve. The swallow motor patterns were evaluated by electromyographic activity (EMG) of eight muscles, based on their functional significance: laryngeal (...) elevators (mylohyoid, geniohyoid, and thyrohyoid); laryngeal adductor (thyroarytenoid); inferior pharyngeal constrictor (thyropharyngeus); upper esophageal sphincter (cricopharyngeus); and inspiratory activity (parasternal and costal diaphragm). Both the fixed and stochastic electrical stimulation paradigms increased activity of the laryngeal elevators, produced short-term facilitation evidenced by increasing swallow durations over the stimulus period, and conversely inhibited swallow-related diaphragm activity. Both the fixed and stochastic stimulus conditions also increased specific EMG amplitudes, which never occurred with the water challenges. Stochastic stimulation increased swallow excitability, as measured by an increase in the number of swallows produced. Consistent with our previous results, changes in the swallow motor pattern for pairs of muscles were only sometimes correlated with each other. We conclude that alterations in afferent feedback produced particular variations of the swallow motor pattern. We hypothesize that specific SLN feedback might modulate the swallow central pattern generator during aberrant feeding conditions (food/liquid entering the airway), which may protect the airway and serve as potentially important clinical diagnostic indicators. (shrink)
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  45.  15
    Re-Mediating Research Ethics: End-User License Agreements in Online Games.Suzanne de Castell,Nicholas T. Taylor &Florence M. Chee -2012 -Bulletin of Science, Technology and Society 32 (6):497-506.
    This article is a theoretical and empirical exploration of the meaning that accompanies contractual agreements, such as the End-User License Agreements (EULAs) that participants of online communities are required to sign as a condition of participation. As our study indicates, clicking “I agree” on the often lengthy conditions presented during the installation and updating process typically permits third parties (including researchers) to monitor the digitally-mediated actions of users. Through our small-scale study in which we asked participants which terms of EULAs (...) they would find agreeable, the majority confirmed that they simply clicked through the terms presented to them without much knowledge about the terms to which they were agreeing. From a research ethics standpoint, we reflect upon whether or not informed consent is achieved in these cases and pose a challenge to the academic research community to attend to the socio-technical shift from informed consent to a more nebulous concept of contractual agreement, online and offline. (shrink)
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  46.  32
    Research in progress: Case studies of family adaptation to changing resources and environments. [REVIEW]M.Suzanne Sontag &Margaret W. Bubolz -1985 -Agriculture and Human Values 2 (1):48-51.
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  47.  46
    Inspired Translation: Synthesizing Qualitative Research and Boot Camp Translation to Achieve Meaningful Community Engagement.Bethany M. Kwan,Suzanne R. Millward,Meleah Himber,Julie Ressalam,Heidi Wald,Matthew Wynia &Marilyn E. Coors -2018 -American Journal of Bioethics 18 (4):29-31.
  48.  20
    Encouraging Sustainable Use of Antibiotics: A Commentary on the DRIVE-AB Recommended Innovation Incentives.Chantal M. Morel &Suzanne E. Edwards -2018 -Journal of Law, Medicine and Ethics 46 (s1):75-80.
    The ability to sustain antibiotic efficacy is directly affected by incentive models aiming to stimulate antibiotic research and development. This paper analyzes the extent to which the models proposed by the Innovative Medicine Initiative-funded research project DRIVE-AB can be expected to support sustainable use, drawing on basic economic theory and the incentives that derive from it. It then discusses the use of minimal safeguards that will be needed to support sustainable use where industry incentives have not been re-aligned with those (...) of public health. (shrink)
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  49. Soorten van gelijk. Medisch-ethische discussies in Nederland.Ineke Bolt,Suzanne Vathorst &M. Trappenburg -1996 -Filosofie En Praktijk 15:209-209.
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  50.  75
    Interview with Professor John M. Dillon.John M. Dillon &Suzanne Stern-Gillet -2018 -International Journal of the Platonic Tradition 12 (2):197-202.
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