Results for 'Spiros D. Dimitratos'
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- Polarizing genetic information in the egg: RNA localization in the frog oocyte.Spiros D.Dimitratos,Daniel F. Woods,Dean G. Stathakis &Peter J. Bryant -1999 -Bioessays 21 (7):546-557.RNA localization is a powerful strategy used by cells to localize proteins to subcellular domains and to control protein synthesis regionally. In germ cells, RNA targeting has profound implications for development, setting up polarities in genetic information that drive cell fate during embryogenesis. The frog oocyte offers a useful system for studying the mechanism of RNA localization. Here, we discuss critically the process of RNA localization during frog oogenesis. Three major pathways have been identified that are temporally and spatially separated (...) in oogenesis. Each pathway uses a different mechanism to effect RNA localization. In some cases, localization elements within the 3' untranslated region have been identified and have provided unique insights into the localization process. This important field is still in its infancy, however, and much remains to be learned. BioEssays 21:546–557, 1999. © 1999 John Wiley & Sons, Inc. (shrink)
- Genomics spawns novel approaches to mosquito control.Robin W. Justice,Harald Biessmann,Marika F. Walter,Spiros D.Dimitratos &Daniel F. Woods -2003 -Bioessays 25 (10):1011-1020.In spite of advances in medicine and public health, malaria and other mosquito‐borne diseases are on the rise worldwide. Although vaccines, genetically modified mosquitoes and safer insecticides are under development, herein we examine a promising new approach to malaria control through better repellents. Current repellents, usually based on DEET, inhibit host finding by impeding insect olfaction, but have significant drawbacks. We discuss how comparative genomics, using data from the Anopheles genome project, allows the rapid identification of members of three protein (...) classes critical to insect olfaction: odorant‐binding proteins, G‐protein‐coupled receptors, and odorant‐degrading enzymes. A rational design approach similar to that used by the pharmaceutical industry for drug development can then be applied to the development of products that interfere with mosquito olfaction. Such products have the potential to provide more complete, safer and longer lasting protection than conventional repellents, preventing disease transmission by interrupting the parasite life cycle. BioEssays 25:1011–1020, 2003. © 2003 Wiley Periodicals, Inc. (shrink)
- Sympathie morale et tragédie sociale : Sophie de Grouchy lectrice d’Adam Smith.Spiros Tegos -2013 -Noesis 21:265-292.Sophie de Grouchy, marquise de Condorcet, réinterprète la doctrine de la sympathie propre à la tradition moraliste écossaise dans le sens d’une réévaluation de ses origines physiologiques, ce qui affecte profondément ses dimensions morales et sociales. Dans le cadre d’un rousseauisme compassionnel, elle transforme Adam Smith en un républicain sentimentaliste modéré, précurseur des Idéologues. Elle s’emploie pour cela à montrer que la déférence envers le pouvoir établi, surtout la royauté, érigée par Adam Smith en servilité quasi fétichiste envers les puissants (...) et les rois, doit être réexaminée dans le cadre d’une économie affective post-révolutionnaire. Malgré le risque d’un mimétisme affectif enflammé par une rhétorique démagogique, Sophie de Grouchy mise sur la moralisation de l’identification avec la souffrance humaine, et sur sa régulation par des lois et institutions réformées pour tenir compte d’une nature humaine profondément sympathique. L’institutionnalisation de la sympathie morale est censée porter remède aux tragédies dues à la ségrégation sociale. En revanche, Adam Smith souligne à la fois la corruption morale due à l’adulation des puissants, et l’illusion socialement utile d’un imaginaire collectif cultivé par la tragédie classique et peuplé d’idéalisations du statut social. Adam Smith explore en outre d’une façon originale une dimension quasi psychanalytique de l’idéal social du moi qui anticipe la problématisation du culte du chef, là où la marquise se contente de critiquer le meneur de foule. (shrink)
- Linguistics without Metaphysics.Spiros A. Moschonas -2019 -Philosophical Inquiry 43 (1):178-210.Based on A. P. D. Mourelatos's "Events, Processes, and States", an overview of the literature on „verb types‟ is provided in this paper;the basic conceptual, logical and grammatical tests for the identification of different verb types are also briefly reviewed.Such tests, it is argued, reveal variations in a verb’s grammatical and/or lexical aspect; accordingly, verb types should be viewed as regularities governing aspectual variation within and across sentences. Verb types are not associated with particular verbs, predicates or sentences; rather, a (...) verb type is the sum of ways in which a verb‟s aspect may vary. In other words, verb types describe the possibilities for a verb to appear in one or another of a series of interrelated constructions. Verb types are verbal possibilities or, to use B. L. Whorf‟s apt term, fashions of speaking which cut across typical grammatical classifications. It is further argued that verb types, as “mere” fashions of speaking, cannot provide a firm basis for any metaphysics of „situation types‟; i.e., the metaphysics of verb types cannot be founded on their linguistics. (shrink)No categories
- The role of ATF‐2 in oncogenesis.Spiros A. Vlahopoulos,Stella Logotheti,Dimitris Mikas,Athina Giarika,Vassilis Gorgoulis &Vassilis Zoumpourlis -2008 -Bioessays 30 (4):314-327.Activating Transcription Factor-2 is a sequence-specific DNA-binding protein that belongs to the bZIP family of proteins and plays diverse roles in the mammalian cells. In response to stress stimuli, it activates a variety of gene targets including cyclin A, cyclin D and c-jun, which are involved in oncogenesis in various tissue types. ATF-2 expression has been correlated with maintenance of a cancer cell phenotype. However, other studies demonstrate an antiproliferative or apoptotic role for ATF-2. In this review, we summarize the (...) signaling pathways that activate ATF-2, as well as its downstream targets. We examine the role of ATF-2 in carcinogenesis with respect to other bZIP proteins, using data from studies in human cancer cell lines, human tumours and mouse models, and we propose a potential model for its function in carcinogenesis, as well as a theoretical basis for its utility in anticancer drug design. (shrink)
- Book Review Section 3. [REVIEW]Violet Anselmini Allain,Richard Moll,John R. Thelin,Neal A. Norris,William J. Lowe,Nicholas C. Polos,W. Bruce Leslie,Jack D. Spiro,Robert R. Sherman,J. Harold Anderson,William F. O'Neill,Ray Nichols,Donna Lee Younker &Thomas A. Brindley -1980 -Educational Studies 11 (3):294-310.No categories
- Vortex/T: The Poetics of Turbulence.Charles D. Minahen -1992 - Pennsylvania State University Press._Vortex/t _undertakes a hermeneutical exploration of symbolic turbulence in many canonical works of literature and philosophy. Charles Minahen's approach is diachronic to the degree that manifestations of the symbol are addressed chronologically, but his aim is not to establish a historical linking of cause and effect, even if such connections do appear. Rather, a synchrony of the symbol is reconstructed that places each discrete example of it in a vibrant intertext of patent and latent meanings. Symbolic turbulence first emerges in (...) ancient "whirls" that display a spiral, spiro-helical, or vertical configuration and usually have cosmic or religious significance. The first significant textual examples of vertical symbolism occur in the Boulak Papyrus, the Bible, and _The Odyssey_, where the destructive connotations of the symbol stand out. For the philosophers and poets of the ancient classical period, including certain Pre-Socrates, Plato, Epicurus, and Lucretius, the vortex is a universal structuring principle, although the underlying causes vary. For Dante, the emphasis is no longer on the dynamic cosmogonic role of the whirl, but on the gradations inherent in the vertical structure itself. Descartes and Blake associated the symbol with the transcendence of a mystical vision, which involves, for the latter, an epiphanal breakthrough. In Poe, the maelstrom excites conflicting feelings of horror in the face of death and curiosity about the "novel" beyond. Rimbaud develops Blake's and Poe's fascination with a transcendent vision, but for Mallarme, the vortex-symbol is Poesque in the more negative way. Not only is it a threatening destructive force, it is the specter of death itself, relentlessly drawing the shipwrecked mariner to ultimate extinction and nonentity. By analyzing, comparing, and contrasting these salient examples of vertical symbolism, _Vortex/t _attempts to uncover and explore the dynamics of emerging and receding meanings that constitute the paradigm's complexity. (shrink)
- La théologie négative chez saint Thomas d'Aquin.T. -D. Humbrecht -1994 -Revue Thomiste 94 (1):71-99.Export citation
Bookmark - The Art of the Greeks. By H. B. Walters. With 112 plates and 18 illustrations in the text. Methuen. 12s. 6d. net.H. D. R. W. -1907 -The Classical Review 21 (06):186-.
- Comments on Lars Bergström's paper “Prawitz's Version of Verificationism”.D. Prawitz -1998 -Theoria 64:293-303.
- Fī al-sīrah wa-al-adab al-Nabawī al-sharīf.Shaltāgh ʻAbbūd -2004 - Bayrūt: Dār al-Hādī.Export citation Bookmark
- Aids Pandemic: Traditional Practices Increasing Risk of HIV Infections in South Africa.Nemutandani M. S. Adedoja D. -2014 -Journal of Clinical Research and Bioethics 5 (2).No categories
- Chronicles.D. B. Allison -1980 -Man and World 13 (3/4):479.Export citation Bookmark
- Critical notices.D. J. Allan -1938 -Mind 47 (185):73-80.No categories
- Fragmenta aristotelica.D. J. Allan -1953 -Philosophical Quarterly 3 (12):248-252.No categories
- Mountain Gloom and Mountain Glory: The Development of the Aesthetics of the InfiniteMarjorie Hope Nicolson.D. Allen -1960 -Isis 51 (2):222-223.
- On Aristotle's Metaphysics.D. J. Allan -1964 -Dialogue 2 (4):454-459.
- The Heyday of Natural History, 1820-1870Lynn Barber.D. Allen -1982 -Isis 73 (3):475-476.
- Theories and their models.D. A. Anapolitanos -1989 -Zeitschrift Für Allgemeine Wissenschaftstheorie 20 (2):201-211.Diese Abhandlung diskutiert und kritisiert einige Aspekte der syntaktischen Auffassung der wissenschaftlichen Theorien und tritt dafür ein, daß die einzig mögliche Alternative eine modell-theoretische Annäherung ist.
- Comments on Aristotle's Theory of Causality.D. Z. Andriopoulos -2016 -Philosophical Inquiry 40 (3-4):120-130.No categories
- Is Aristotle an Empiricist? Is he an Ant, a Spider or a Bee?D. Z. Andriopoulos -1998 -Philosophical Inquiry 20 (1-2):83-100.
- Photoconductivity and recombination in doped amorphous silicon.D. A. Anderson &W. E. Spear -1977 -Philosophical Magazine 36 (3):695-712.No categories
- Reconstructing and Commenting Polybiu's Philosophy of History.D. Z. Andriopoulos -2015 -Philosophical Inquiry 39 (2):15-34.No categories
- Sebastian Gardner, Irrationality and the Philosophy of Psychoanalysis.D. Archard -forthcoming -Radical Philosophy.Export citation Bookmark
- The Educator's Impossible Dream: Knowledge as an Educational Aim'.D. Arnstine -forthcoming -Philosophy of Education.
- In-plane and out-of-plane anisotropic magnetoresistances in La1 −xPbxMnO3thin films.D. K. Aswal,A. Singh,C. Thinaharan,S. M. Yusuf,C. S. Viswanadham,G. L. Goswami,L. C. Gupta,S. K. Gupta,J. V. Yakhmi &V. C. Sahni -2003 -Philosophical Magazine 83 (28):3181-3191.No categories
- Histoire de fractions, fractions d'histoire.G. Canepa &D. Palladino -1996 -Epistemologia 19 (1):182-183.Export citation Bookmark
- Problema universaliĭ: sovremennyĭ vzgli︠a︡d.G. D. Levin -2005 - Moskva: Kanon+.
- ʻIndamā yatakallamu al-faylasūf D. Zakī Najīb Maḥmūd.Zakī Najīb Maḥmūd -2001 - [Cairo]: al-Hayʼah al-Miṣrīyah al-ʻĀmmah lil-Kitāb. Edited by Fāṭimah Barakah.Maḥmūd, Zakī Najīb, 1905-; philosophers; Egypt; biography; interview.No categories
- A Study of History: Abridgement of Volumes I-X Bij D.C. Somervell.Arnold Joseph Toynbee &D. C. Somervell -1947 - Oxford University Press.
- Andersson, A., On second-order generalized quanti" ers and" finite structures.D. R. Hirschfeldt,B. Khoussainov,R. A. Shore &A. M. Slinko -2002 -Annals of Pure and Applied Logic 115:303.
- What pleases the prince: Justinian, Napoleon and the lawyers.D. Kelley -2002 -History of Political Thought 23 (2):288-302.Following the precedent of Justinian, First Consul and then Emperor Napoleon proposed to enhance his military achievements with a legal Code based on the riches of Roman law and a system of legal education designed to perpetuate it. Like Justinian, Napoleon prohibited 'interpretation' of his creation on the grounds that this would contravene imperial will -- as opposed to the countervailing principle of popular sovereignty. Yet in neither case could the prince stop history, for in the effort to adapt the (...) code to changing conditions of society later jurists promoted just such subversive violations. (shrink)
- An Exception To The Rule: Journalism And Research Ethics.D. Matheson -2018 - In Ron Iphofen & Martin Tolich,The Sage Handbook of Qualitative Research Ethics. Los Angeles: Sage.This chapter argues that journalism’s ethical frameworks, particularly at moments when it is making its grandest claims to value, collide with those prevalent within universities and particularly with ethical review structures. Working through these tensions requires some accommodation from all sides, and also provides opportunities for learning. The chapter discusses how universities might recognize the ethics systems particular to practices, like journalism, which set out to serve the public good and which produce knowledge in ways distinctive to that practice. Underneath (...) this problem is the more fundamental question of how to establish the boundaries between research and other activities that take place in the university. The chapter proposes, following Spicker’s argument in relation to policy studies, that distinctive ethical criteria must be recognized in different areas of university activity where claims to be producing research are being made. Yet it must also be noted that exceptionalism risks leaving university-based journalists with a weak ethical system. It concludes that journalists within the university have both the opportunity and obligation to extend their practice by using university processes to engage with a wide range of ethical frameworks. (shrink)No categories
- In Platonis Phaedrum scholia. Hermeias &Hermias D'Alexandrie -2012 - Berlin: De Gruyter. Edited by Carlo M. Lucarini & Claudio Moreschini.Die Bibliotheca Teubneriana, gegründet 1849, ist die weltweit älteste, traditionsreichste und umfangreichste Editionsreihe griechischer und lateinischer Literatur von der Antike bis zur Neuzeit. Pro Jahr erscheinen 4-5 neue Editionen. Sämtliche Ausgaben werden durch eine lateinische oder englische Praefatio ergänzt.
- Prenatal diagnosis: whose right?D. Heyd -1995 -Journal of Medical Ethics 21 (5):292-297.The question who is the subject of the right to prenatal diagnosis may be answered in four ways: the parents, the child, society, or no one. This article investigates the philosophical issues involved in each of these answers, which touch upon the conditions of personal identity, the principle of privacy, the scope of social responsibility, and the debate about impersonalism in ethics.
- (1 other version)The Relevance of Capital to Studies of Bureaucracy.D. C. Hodges -1970 -Télos 1970 (6):234-243.
- The descriptive method in philosophy.D. T. Howard -1919 -Philosophical Review 28 (4):379-390.
- Teoría de las virtudes: un nuevo enfoque de la epistemología (Parte I).D. Hoyos -2005 -Discusiones Filosóficas 6 (9).No categoriesExport citation Bookmark
- A note on Foucault account of psychology from 1850 to 1950.D. Huisman -1990 -Revue Internationale de Philosophie 44 (173):177-178.Export citation Bookmark
- Abū Ḥayyān al-Tawḥīdī: al-Muqābasāt: faṣl al-dīn ʻan al-dawlah, faṣl al-dīn ʻan al-falsafah.ʻAbd al-Razzāq ʻĪd -2001 - Dimashq: al-Ahālī.Export citation Bookmark
- Cicero, Ad Atticum i. 14. 4.D. C. Innes -1966 -The Classical Review 16 (02):145-146.
- Menander Rhetor.D. C. Innes -1978 -The Classical Review 28 (01):23-.
- Talking to the Media: An Australian Perspective.D. A. Ipp -1998 -Legal Ethics 1 (2):123-125.
- A. Sharf, Byzantine Jewry from Justinian to the Fourth Crusade.D. Jacoby -1973 -Byzantinische Zeitschrift 66 (2).No categories
- Tabula Imperii Byzantini.D. Jacoby -1984 -Byzantinische Zeitschrift 77 (2).No categories
- Muqaddimah li-dirāsat al-fikr al-ʻIbrī al-wasīṭ.Aḥmad Jaddād -2010 - [Safi, Morocco?: [S.N.].Export citation Bookmark
- Mabādiʼ ʻilm al-ijrām wa-ʻilm al-ʻiqāb.Sāmiḥ al-Sayyid Jād -1976 - al-Qāhirah: Dār al-Kitāb al-Jāmiʻī.Export citation Bookmark
- Fichte's republicanism: Education, philosophy and the bonds of reason.D. James -2014 -History of Political Thought 35 (3):485-518.The article shows how Fichte's rarely discussed Deduced Plan for a Higher Institute of Learning to be Established in Berlin plays an essential role in his thought from around the time of the more famous Addresses to the German Nation, and in so doing it identifies some of the essential features of the future German republic that he has in mind. For Fichte, the university prepares individuals for the standpoint of the Wissenschaftslehre, while the love of learning for its own (...) sake demanded and fostered by this philosophical science helps to produce the kind of ethical disposition, namely, love of fatherland, that the members of the German nation need to possess if this nation is to free itself from subjection to an alien, external power. Moreover, the systematic unity aimed at by true philosophy finds its practical correlate in the idea of the nation. However, by identifying the laws of pure reason as the bonds that unite themembers of a future German republic in the way that he does, Fichte ends up reducing ethical acts to a matter of necessity rather than freedom. (shrink)Export citation Bookmark
- The English Augustans. I : The Life of Reason, Hobbes, Locke, Bolingbroke.D. G. James -1953 -Revue Philosophique de la France Et de l'Etranger 143:268-269.Export citation Bookmark
- Habiter l'habitude: Ravaisson: l'intelligence de l'habitude.D. Janicaud -1993 -Les Etudes Philosophiques 1:17-23.Export citation Bookmark
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David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Area Editors:
David Bourget
Gwen Bradford
Berit Brogaard
Margaret Cameron
David Chalmers
James Chase
Rafael De Clercq
Ezio Di Nucci
Esa Diaz-Leon
Barry Hallen
Hans Halvorson
Jonathan Ichikawa
Monte Johnson
Michelle Kosch
Øystein Linnebo
Paul Livingston
Brandon Look
Manolo Martínez
Matthew McGrath
Michiru Nagatsu
Susana Nuccetelli
Giuseppe Primiero
Jack Alan Reynolds
Darrell P. Rowbottom
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