Gene–environment interaction: why genetic enhancement might never be distributed fairly.SineadPrince -2024 -Journal of Medical Ethics 50 (4):272-277.detailsEthical debates around genetic enhancement tend to include an argument that the technology will eventually be fairly accessible once available. That we can fairly distribute genetic enhancement has become a moral defence of genetic enhancement. Two distribution solutions are argued for, the first being equal distribution. Equality of access is generally believed to be the fairest and most just method of distribution. Second, equitable distribution: providing genetic enhancements to reduce social inequalities. In this paper, I make two claims. I first (...) argue that the very assumption that genetic enhancements can be distributed fairly is problematic when considering our understanding of gene–environment interactions, for example, epigenetics. I then argue that arguments that genetic enhancements are permissible because the intended benefits can be distributed fairly as intended are misinformed. My first claim rests on the assertion that genetic enhancements do not enhance traits in a vacuum; genes are dependent on conducive environments for expression. If society cannot guarantee fair environments, then any benefit conferred from being genetically enhanced will be undermined. Thus, any argument that the distribution of genetic enhancements will be fair and that the technology is therefore morally permissible, is mistaken. (shrink)
Is germline genome‐editing person‐affecting or identity‐affecting, and does it matter?Andrew McGee &SineadPrince -2025 -Bioethics 39 (3):250-258.detailsWriters have debated whether germline genome‐editing is person‐affecting or identity‐affecting. The difference is thought to be ethically relevant to whether we should choose genome‐editing or choose preimplantation genetic diagnosis and embryo selection, when seeking to prevent or produce bad conditions (e.g., cystic fibrosis, or deafness) in the individuals who will grow from the embryo edited or selected. We consider the very recent views of three prominent bioethicists and philosophers who have grappled with this issue. We claim that both sides are (...) right, but that the sense in which genome‐editing is person‐affecting is less important, morally, when the aim is to have healthy children. Since this is the predominant objective of engaging in embryo selection and genome‐editing, and since there are certain risks, at least for now, with genome‐editing, it remains better, morally, to engage in embryo selection than genome‐editing. (shrink)
Understanding genetic justice in the post-enhanced world: a reply toSineadPrince.Jon Rueda -2023 -Journal of Medical Ethics (4):287-288.detailsIn her recent article,Prince has identified a critical challenge for those who advocate genetic enhancement to reduce social injustices. The gene–environment interaction prevents genetic enhancement from having equitable effects at the phenotypic level, even if enhancement were available to the entire population. The poor would benefit less than the rich from their improved genes because their genotypes would interact with more unfavourable socioeconomic environments. Therefore,Prince believes that genetic enhancement should not be used to combat social inequalities, (...) since it can likely aggravate them. In this article, I raise various objections to this conclusion. I argue first that genetic enhancement need not necessarily magnify social injustices. I then show that genetic enhancement can play a modest but not insignificant role in the quest for social justice in the future. Finally, I conclude by arguing for the need to consider the complex interplay between the social lottery and the natural lottery in our aspirations for justice linked to genetic technologies. (shrink)
The Information Value of Non-Genetic Inheritance in Plants and Animals.Sinead English,Ido Pen,Nicholas Shea &Tobias Uller -2015 -PLoS ONE 10 (1):e0116996.detailsParents influence the development of their offspring in many ways beyond the transmission of DNA. This includes transfer of epigenetic states, nutrients, antibodies and hormones, and behavioural interactions after birth. While the evolutionary consequences of such nongenetic inheritance are increasingly well understood, less is known about how inheritance mechanisms evolve. Here, we present a simple but versatile model to explore the adaptive evolution of non-genetic inheritance. Our model is based on a switch mechanism that produces alternative phenotypes in response to (...) different inputs, including genes and non-genetic factors transmitted from parents and the environment experienced during development. This framework shows how genetic and non-genetic inheritance mechanisms and environmental conditions can act as cues by carrying correlational information about future selective conditions. Differential use of these cues is manifested as different degrees of genetic, parental or environmental morph determination. We use this framework to evaluate the conditions favouring non-genetic inheritance, as opposed to genetic determination of phenotype or within-generation plasticity, by applying it to two putative examples of adaptive non-genetic inheritance: maternal effects on seed germination in plants and transgenerational phase shift in desert locusts. Our simulation models show how the adaptive value of non-genetic inheritance depends on its mechanism, the pace of environmental change, and life history characteristics. (shrink)
Effective history: on critical practice under historical conditions.Sinead Murphy -2010 - Evanston, Ill.: Northwestern University Press.detailsHabermas: a closet Kantian -- Kant -- Vattimo: a closet Kantian -- Gadamer and Lyotard on aesthetic judgment (I): some problems -- Gadamer and Lyotard on aesthetic judgment (II): the story of where they go wrong.
The Dangers of "Pure Feeling": A Warning to Feminist Interpretations of Hans-Georg Gadamer.Sinéad Murphy -2014 -Labyrinth: An International Journal for Philosophy, Value Theory and Sociocultural Hermeneutics 16 (1):92-108.detailsBy analyzing the feminist debates on Hans-Georg Gadamer, the author shows that feminist critics point to the need either to supplement or to replace Gadamer's philosophy with a greater sensitivity to the historical implications of women's experience. Thus, they are of the view either that Gadamer's philosophy has yet to come to terms with specific historical situations or that Gadamer's philosophy cannot come to terms with historical situatedness per se. The author contends that Gadamer's femi-nist critics do not locate the (...) source of his residual transcendentalism where it should be located: in the account of aesthetic judgment as a "pure feeling" that underpins his entire philosophy. This has the effect, of appearing to preserve aesthetic judgment as "pure feeling" as an apparently innocent remedy, to which some of his feminist critics actually appeal in opposition to his transcendentalism. The author argues, to the contrary, that aesthetic judgment, as a "pure feeling," is at once too com-plicit in the tradition that feminists seek to engage with, traditionally too insubstantial to make a rich resource for a feminist critique of that tradition, and ultimately too traditionally male-centered to be easily coopted by a feminist philosopher. (shrink)
Assessing Sensorimotor Synchronisation in Toddlers Using the Lookit Online Experiment Platform and Automated Movement Extraction.Sinead Rocha &Caspar Addyman -2022 -Frontiers in Psychology 13.detailsAdapting gross motor movement to match the tempo of auditory rhythmic stimulation is a complex skill with a long developmental trajectory. Drumming tasks have previously been employed with infants and young children to measure the emergence of rhythmic entrainment, and may provide a tool for identification of those with atypical rhythm perception and production. Here we describe a new protocol for measuring infant rhythmic movement that can be employed at scale. In the current study, 50 two-year-olds drummed along with the (...) audiovisual presentation of four steady rhythms, using videos of isochronous drumming at 400, 500, 600, and 700 ms IOI, and provided their spontaneous motor tempo by drumming in silence. Toddlers’ drumming is observed from video recordings made in participants’ own homes, obtained via the Lookit platform for online infant studies. We use OpenPose deep-learning model to generate wireframe estimates of hand and body location for each video. The vertical displacement of the hand was extracted, and the power and frequency of infants’ rhythmic entrainment quantified using Fast Fourier Transforms. We find evidence for age-appropriate tempo-flexibility in our sample. Our results demonstrate the feasibility of a fully digital approach to measuring rhythmic entrainment from within the participant’s home, from early in development. (shrink)
Ethics of Youth Work Practice in the Twenty-First Century: Change, Challenge and Opportunity.Sinead McMahon,Catherine Forde &Gunjan Wadhwa -2024 -Ethics and Social Welfare 18 (2):107-114.detailsOur editorial introduces this Special Issue devoted to exploring the ethics of youth work practice in the twenty-first century. The call for papers for this Special Issue went out in October 2022 w...
An investigation of the potential existence of "food deserts" in rural and urban areas of Northern Ireland.Sinéad Furey,Christopher Strugnell &Ms Heather McIlveen -2001 -Agriculture and Human Values 18 (4):447-457.detailsFood Deserts have recently beenidentified in the United Kingdom. They havebeen defined by Tessa Jowell, UK GovernmentHealth Minister, as an area ``where people donot have easy access to healthy, fresh foods,particularly if they are poor and have limitedmobility.'' The above definition is particularlyrelevant in Northern Ireland, where it isestimated that 32% of households do not haveeasy access to a car and it is recognized thatcertain groups in Northern Ireland are amongstthe poorest consumers in the United Kingdom.The phenomenon has been further (...) exacerbated bythe effect of large grocery retailers locatingon the periphery of towns and the subsequentdisplacement effect of independent retailers inthe town center. The resultant effect is suchthat disadvantaged consumers cannot accessfresh, quality, nutritious foods at anaffordable price. Preliminary researchindicates that certain consumer groups areexcluded from equitable shopping provision –possibly to the detriment of their healthstatus. Research methodology includes aconsumer questionnaire, consumer focus groups,interviews, and comparative shopping exercisesthat confirm an inability among vulnerableconsumer groups to achieve an affordable,healthy diet. This was further complicated bynon-car owners' and lower-income family unitsneeding to shop locally and more frequentlythan their higher-income, car-ownercounterparts. This was demonstrated with theuse of shopping diaries. Future research to beconducted includes a large-scale survey acrossNorthern Ireland to ascertain accessibility,availability, and affordability of qualityfresh foods and to distinguish the consumergroups who are most vulnerable. (shrink)
Maternal Belongings and the Question of ‘Home’ in Mary Morrissy’s ‘Mother of Pearl’.Sinead McDermott -2003 -Feminist Theory 4 (3):263-282.detailsThis essay addresses the relationship between home, belonging and the maternal in feminist theory and fiction. Feminist discourse isoften typified by its critique of home: analysing the gendered assumptions underlying the depiction of home as nurturing, or exposing the regressive and essentialist connotations of the search for safe homes. A number of recent feminist theorists (Probyn, Bammer, Young) have, however, pointed to thepersistence of ‘retrograde’ desires for safety and belonging, particularly in an era of widespread dislocations. At the same time, (...) feminist critics such as Roberta Rubenstein have re-invoked the contested relationship between home and the maternal by arguing that the desire for home speaks to our earliest needs for security: a desire that ultimately maps on to a longing for the (idealized) mother as the ‘original safe home’ (Rubenstein, 2001). This essay draws upon the work of Rubenstein, Bammer and Young in order to examine the relationship between home and the maternal in a recent Irish novel, Mary Morrissy’s Mother of Pearl. The plot of this novel, dealing with the events surrounding an incident of baby snatching, suggests both the persistence of (the maternal) home as a desire and the impossibility of identifying an original or authentic maternal/home. By exploring how the protagonists of this novel negotiate the demands and appeals of home and motherhood, this essay will ask to what extent it may be possible for feminism to recuperate, or re-envision, the maternal/home as utopian ideal. (shrink)
No categories
e-Agricultural innovation using a human-centred systems lens, proposed conceptual framework.Sinead Somers &Larry Stapleton -2014 -AI and Society 29 (2):193-202.detailsHistorically, farmers have been amongst the most innovative people in the world. However, agriculture now lags behind other sectors in its uptake of new information technologies for the control and automation of farming systems. In spite of decades of research into innovation, we still do not have a good understanding as to why this is the case. With the globalisation of food markets, IT adoption in agricultural communities is perceived to be increasingly important by policy makers. As the most marginalised (...) of rural communities, it is self-evident that agricultural communities in less developed countries are most in need of these systems. This paper proposes a new integral systems framework of e-agricultural adoption and innovation in less developed countries. It opens up a new avenue of research for control and automation systems theory and practice, which informs policy in respect of e-readiness of rural communities. (shrink)
Gender bias perpetuation and mitigation in AI technologies: challenges and opportunities.Sinead O’Connor &Helen Liu -forthcoming -AI and Society:1-13.detailsAcross the world, artificial intelligence (AI) technologies are being more widely employed in public sector decision-making and processes as a supposedly neutral and an efficient method for optimizing delivery of services. However, the deployment of these technologies has also prompted investigation into the potentially unanticipated consequences of their introduction, to both positive and negative ends. This paper chooses to focus specifically on the relationship between gender bias and AI, exploring claims of the neutrality of such technologies and how its understanding (...) of bias could influence policy and outcomes. Building on a rich seam of literature from both technological and sociological fields, this article constructs an original framework through which to analyse both the perpetuation and mitigation of gender biases, choosing to categorize AI technologies based on whether their input is text or images. Through the close analysis and pairing of four case studies, the paper thus unites two often disparate approaches to the investigation of bias in technology, revealing the large and varied potential for AI to echo and even amplify existing human bias, while acknowledging the important role AI itself can play in reducing or reversing these effects. The conclusion calls for further collaboration between scholars from the worlds of technology, gender studies and public policy in fully exploring algorithmic accountability as well as in accurately and transparently exploring the potential consequences of the introduction of AI technologies. (shrink)
Banning Puberty-Pausing Medications Endangers Transgender Adolescents.Sinead Murano-Kinney -2024 -American Journal of Bioethics 24 (8):4-8.detailsVolume 24, Issue 8, August 2024, Page 4-8.
Unshakable hope: joyful expectation in every season.DerekPrince -2019 - Shippensburg, PA: Destiny Image Publishers.detailsRenowned preacher and author, DerekPrince writes on the power of hope as... a window into God's perspective of reality; a sure anchor in every one of life's storms; a deep well from which to draw during times of spiritual drought; a supernatural force, empowering persistence in prayer until God's promises are manifest"--cover, page 4.
Minors and refusal of medical treatment: a critique of the law regarding the current lack of meaningful consent with regards to minors and recommendations for future change.Sinead O'Brien -2012 -Clinical Ethics 7 (2):67-72.detailsThe autonomous right of competent adults to decide what happens to their own body and the corresponding right to consent to or refuse medical treatment are cornerstones of modern health care. For minors the situation is not so clear cut. Since the well-known case of Gillick, mature children under the age of 16 can agree to proposed medical treatment. However, those under the age of 18 do not enjoy any corresponding right to refuse medical treatment. Can this separation of the (...) right to agree to treatment and the right to refuse treatment for those under 18, regardless of capacity, be justified? This paper evaluates the key cases in this area of the law. Changes to the current law are then proposed which aim to make the law more consistent and reasonable. (shrink)
Self‐care as care left undone? The ethics of the self‐care agenda in contemporary healthcare policy.Anna-Marie Greaney &Sinead Flaherty -2020 -Nursing Philosophy 21 (1):e12291.detailsSelf‐care, or self‐management, is presented in healthcare policy as a precursor to patient empowerment and improved patient outcomes. Alternatively, critiques of the self‐care agenda suggest that it represents an over‐reliance on individual autonomy and responsibility, without adequate support, whereby ‘self‐care’ is potentially unachievable and becomes ‘care left undone’. In this sense, self‐care contributes to a blame culture where ill‐health is attributed to personal behaviours or lack thereof. Furthermore, self‐care may represent a covert form of rationing, as the fiscal means to (...) enable effective self‐care and supplement, or replace, self‐care capacities, is not provided. This paper explores these arguments through a contemporary ethical analysis of the self‐care agenda. The terms self‐care and self‐management are used interchangeably throughout whereby self‐management is understood as a point in the wider self‐care continuum. (shrink)
Support for making Pauline henotic unity the fulcrum of Christian ecumenism in Nigeria.Prince E. Peters -2021 -HTS Theological Studies 77 (1).detailsPaul uses the word ἑνότης twice in Ephesians, and quite strangely, those are the only two places where the feminine noun features in the whole of the New Testament. In the two passages where they appear, they both relate to invisible unity, the unity of the Spirit that produces a common faith and knowledge of the Son of God – εἰς τὴν ἑνότητα τῆς πίστεως καὶ τῆς ἐπιγνώσεως τοῦ υἱοῦ τοῦ Θεοῦ. Such unity suggests that ecumenism amongst Christian denominations is (...) not only a possibility, it is also a necessity as far as we all profess one Christ. This unity is however far from ecclesiological unionism. Considering that the church appears weak from the outside when its diverse lines of doctrine, sacraments and ministerial ethics are emphasised. This suggests that a reasonable antidote would be the emphasis on the philosophy of unity amidst our diversity especially to the hearing of non-Christians.Contribution: This study makes firm the belief that Christianity is formed on divergent traditions that produced various strands of practices, which in turn produce different Christian sects and denominations, and a reverse is not possible. It then suggests a bonding in faith through the invisibility of henotic unity, which the pericope suggests. This will help the church to amass a stronger defence politically and structurally against rival religions and social organisations even in the midst of doctrinal differences. (shrink)
Counterfactuality and past.Kilu vonPrince -2019 -Linguistics and Philosophy 42 (6):577-615.detailsMany languages have past-and-counterfactuality markers such as English simple past. There have been various attempts to find a common definition for both uses, but I will argue in this paper that they all have problems with ruling out unacceptable interpretations, or accounting for the contrary-to-fact implicature of counterfactual conditionals, or predicting the observed cross-linguistic variation, or a combination thereof. By combining insights from two basic lines of reasoning, I will propose a simple and transparent approach that solves all the observed (...) problems and offers a new understanding of the concept of counterfactuality. (shrink)
Philosophical Dialogue in the British Enlightenment: Theology, Aesthetics and the Novel.MichaelPrince -1996 - Cambridge University Press.detailsThis book offers the first full-length study of philosophical dialogue during the English Enlightenment. It explains why important philosophers - Shaftesbury, Mandeville, Berkeley and Hume - and innumerable minor translators, imitators and critics wrote in and about dialogue during the eighteenth century; and why, after Hume, philosophical dialogue either falls out of use or undergoes radical transformation. Philosophical Dialogue in the British Enlightenment describes the extended, heavily coded, and often belligerent debate about the nature and proper management of dialogue; and (...) it shows how the writing of philosophical fictions relates to the rise of the novel and the emergence of philosophical aesthetics. Novelists such as Fielding, Sterne, Johnson and Austen are placed in a philosophical context, and philosophers of the empiricist tradition in the context of English literary history. (shrink)
Promising Under Duress.Prince Saprai -2019 -Law and Philosophy 38 (5-6):465-480.detailsIn her chapter “Duress and Moral Progress”, Seana Shiffrin offers a novel perspective on coerced promises. According to the dominant view, these promises confer no right to performance on the coercer and do not create new reasons for the victim. Shiffrin accepts that these promises fail to confer rights, but disagrees that they never alter the victim’s moral profile. She argues that they do at least where promises are ‘initiated’ by the victim, rather than ‘dictated’ by the coercer. The initiation (...) of a promise, albeit in far from ideal circumstances, opens the door, Shiffrin claims, to valuable opportunities for moral progress. In this response, I argue that Shiffrin makes a misstep by not rejecting the dominant view altogether. I suggest that the older Hobbesian picture, according to which coerced promises do confer rights, is supported by our moral and legal practices. Furthermore, it makes moral progress more likely. (shrink)
The Penalties Rule and the Promise Theory of Contract.Prince Saprai -2013 -Canadian Journal of Law and Jurisprudence 26 (2):443-469.detailsThe rule against penalty clauses in contract law sits uneasily with the promise theory of contract. According to the rule, if contracting parties agree a monetary remedy for breach which is substantially in excess of what would be required to compensate the claimant then that remedy is not enforceable. If contracts enforce promises however one would expect to see these clauses enforced. The rule appears therefore to be an example of a contract doctrine that diverges from promise. Promise theorists tend (...) to respond to divergent doctrines in one of three ways, they either: seek to accommodate these doctrines within the promise principle, or they repudiate them, or finally they justify these doctrines on the basis of the specific legal context within which they operate.I argue that in the case of the penalties rule all of these standard responses would fall short. These responses are inadequate because they are premised on the claim that the promise principle is the only general moral principle relevant to evaluating contract law, or that it has overriding justificatory priority when it conflicts with other moral concerns. I argue that a richer conception of the moral principles that bear on contract and how they interact offers a way forward for justifying the rule. (shrink)
Jesus’ identity in Matthew 16:13–20 and identity crisis among gospel preachers in Nigeria.Prince E. Peters,Kalu O. Ogbu &Nnamdi U. Ijeudo -2024 -HTS Theological Studies 80 (1):8.detailsThe Jesus’ question which was encased in his shadowy identity was both a fascinating and enigmatic phenomenon to people of Jesus time as well as people of today. The synoptic gospels presented the matter of Jesus identity in varying contexts; however, it is approached in this study from the context of Matthew. After receiving a brief answer of ‘who he is’ from Peter, Jesus mandates his disciples to keep the information to themselves. This mandate to secrecy shares certain characteristics with (...) the Messianic secret in Mark, but differs in intentions. From the exegesis of the pericope in Matthew, Jesus’ refusal to let the public know about his personalities with his motive to keep away from ostentation and self-love. Such ostentation and self-love have been referred to in this study as identity crisis. This study argues from empirical evidence that many Nigerian pastors suffer from identity crisis. It therefore, challenges Nigerian contemporary preachers to emulate Jesus’ refusal of self-seeking and to shun hypocrisy and unnecessary publicity. Contribution: To reroute the Christian church in Nigeria, especially the pastors from ostentation and self-seeking publicity to a selfless and modest lifestyle modelled after Jesus’ own personality example according to Matthew 16:13–20. (shrink)