Results for 'Samuel K. Handelman'
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- A new framework for host-pathogen interaction research.Hong Yu,Li Li,Anthony Huffman,John Beverley,Junguk Hur,Eric Merrell,Hsin-hui Huang,Yang Wang,Yingtong Liu,Edison Ong,Liang Cheng,Tao Zeng,Jingsong Zhang,Pengpai Li,Zhiping Liu,Zhigang Wang,Xiangyan Zhang,Xianwei Ye,Samuel K.Handelman,Jonathan Sexton,Kathryn Eaton,Gerry Higgins,Gilbert S. Omenn,Brian Athey,Barry Smith,Luonan Chen &Yongqun He -2022 -Frontiers in Immunology 13.COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)
- Artistic Practice and Education in India: A Historical Overview.Samuel K. Parker -1987 -The Journal of Aesthetic Education 21 (4):123.
- La storia secondo Robert Putnam.Samuel K. Cohn -1994 -Polis 8 (2):315-324.
- This Anti-Catholic Madness.Samuel K. Wilson -1928 -Thought: Fordham University Quarterly 3 (3):357-374.
- State Materialism in the United States.Samuel K. Wilson -1937 -Thought: Fordham University Quarterly 12 (1):31-41.
- Using Diffusion Tensor Imaging to Probe Mental Status in Legal Cases: Ethical Concerns and Lessons Learned from Other Biotechnologies.Samuel K. Powell,Nehal A. Parikh &Robin N. Fiore -2014 -American Journal of Bioethics Neuroscience 5 (2):46-47.
- Book Review: Genetics and Christian Ethics. [REVIEW]Samuel K. Roberts -2008 -Interpretation: A Journal of Bible and Theology 62 (1):107-107.
- Sefer Yovel Li-Khevod Shemu El Kalman Mirski Li-Melot Sheloshim Shanah la- Avodato Ha-Berukhah Bi- Sedeh Ha-Mada Ve-Harbatsat Ha-Torah Be-Amerikah.Samuel K. Mirsky,S. Bernstein &Gershon Churgin -1958 - Va Ad Ha-Yovel.No categoriesExport citation
Bookmark - The Rise of American Civllization. [REVIEW]Samuel K. Vvilson -1927 -Thought: Fordham University Quarterly 2 (2):336-342.
- The Pageant of the Packets. [REVIEW]Samuel K. Wilson -1930 -Thought: Fordham University Quarterly 5 (3):515-519.
- Epidemics that End with a Bang.Samuel K. Cohn -2022 -Centaurus 64 (1):207-216.To answer how epidemics end, one must ask two intersecting but separate questions: first, how particular waves of epidemics end, whether of yellow fever, cholera, plague; and second, how epidemic diseases become eradicated-either through scientific intervention, as with smallpox in the 1970s, or simply by disappearing for reasons that remain mysterious, as with the Second Plague Pandemic from ca. 1347. This article challenges two general notions on how epidemics end. First, individual waves of plagues in European municipalities or regional states (...) did not just fade into the sunset. By the late 16th century, their ends were celebrated with artistic displays, musical and poetic performances, ex-voto gifts, and bangs ranging from tambourines to military salutes. Second, the five-century Second Pandemic of plague-that is, the disease-did not end with declarations or scripted performances, but with another sort of bang. Instead of the usual assumption that epidemic diseases decline gradually over time, progressively inflicting lighter loads of virulence and mortality, the last significant plague outbreaks in most regions in Europe returned to heights of mortality not seen since the Black Death of 1347-1351. Finally, this article adds an obvious but rarely mentioned variable for understanding epidemic endings. Before widespread vaccination, the characteristics of these disappearances depended on the type of disease. (shrink)No categories
- Infertility, abortion, and biotechnology.Samuel K. Wasser -1990 -Human Nature 1 (1):3-24.Patterns of reproductive failure described in humans and other mammals suggest that reproductive failure may in many instances be the result of adaptations evolved to suppress reproduction under temporarily harsh conditions. By suppressing reproduction under such conditions, females are able to conserve their time and energy for reproductive opportunities in which reproduction is most likely to succeed. Such adaptations have been particularly important for female mammals, given (a) the amount of time and energy that reproduction requires, and (b) the degree (...) to which reproductive conditions can vary.The existence of conscious and unconscious mechanisms to suppress reproduction under poor conditions has several implications for obstetric/gynecologic practices. Two implications are discussed with reference to biotechnological advancements in our ability to facilitate conceptions and manage problem pregnancies: (a) potential dangers of sophisticated technologies overriding natural fertility controls; and (b) the need for greater appreciation of the association between psychosocial stress and reproductive failure in the treatment of reproductive problems. Implications for elective abortion practices are discussed as well. (shrink)
- Cotton Mather. [REVIEW]Samuel K. Wilson -1926 -Thought: Fordham University Quarterly 1 (1):179-183.
- The Genesis of American College Government.Samuel K. Wilson -1926 -Thought: Fordham University Quarterly 1 (3):415-433.
- African American Christian ethics.Samuel K. Roberts -2001 - Cleveland: Pilgrim Press.
- Becoming the Neighbor: Virtue Theory and the Problem of Neighbor Identity.Samuel K. Roberts -2008 -Interpretation: A Journal of Bible and Theology 62 (2):146-155.Ethical theories consistent with Christian moral sensibilities must assure each neighbor's dignity and recognize his or her unique needs. While utilitarian ethics and duty-based ethics may fail to some degree in these respects, virtue ethics offers perspectives that echo more faithfully the parable of the Good Samaritan.
- Psychosocial stress and infertility.Samuel K. Wasser -1994 -Human Nature 5 (3):293-306.Experimental, theoretical, psychological, and economic barriers have caused physicians to rely on biomedical treatments for infertility at the exclusion of more environmentally oriented ones (e.g., psychosocial stress therapy). An evolutionary model is described for the origin of reproductive failure, suggesting why mammals evolved to be reproductively responsive to the environment and why psychosocial stress should have an especially strong impact on fertility problems. A study of the causal role of psychosocial stress in infertility is then summarized. The paper concludes with (...) implications for future directions for the treatment of infertility and related human reproductive problems. (shrink)
- The King Is Dead. Studies in the near Eastern Resistance to Hellenism, 334-31 B. C.Carl H. Kraeling &Samuel K. Eddy -1964 -Journal of the American Oriental Society 84 (4):431.No categories
- Dialogic theology of missions as a response to the global refugee phenomenon.Shakespeare Sigamoney &Samuel K. B. Nkrumah-Pobi -2024 -HTS Theological Studies 81 (1):7.The legacies of colonialism on both the colonised and coloniser is one thing that our world cannot escape in contemporary times. In most of the places, colonialism came with its own form of Christianity. This colonial Christianity was based on the idea of exclusion, homogenisation and conquering the other. Thus, the combination of the ideals of colonialism and Christianity brought about a type of nationalism, which was monologic. This monologic nationalism as an ideology not only creates refugees but also generates (...) a monological ‘unity’ among the people in the country of arrival against these refugees. This poses a danger to humanity as a whole. Thus, it is important for scholars of religion and theology to deconstruct ideas on the line of monologic nationalism and embrace a form of nationalism that is dialogical in nature. In this regard, this article using Mikhail Bakhtin’s idea of dialogism as its framework attempts to construct a dialogic theology of missions as a response to the global refugee phenomenon. The article argues that there must be a shift from colonial missions, which are monologic in nature to a dialogic theology of missions grounded in World Christianity.Contribution: This article attempts to point out a key legacy of colonialism and colonial Christianity: the creation of refugees, which often has not been looked at by many scholars. The problem lies not with ‘Christianity’ as a religion, but the type of Christianity being practised. Addressing this practice demands a shift from colonial Christianity to World Christianity, which is embedded within its solutions to the global refugee crisis that the world is currently facing. (shrink)
- The Oxford History of the United States. [REVIEW]Samuel K. Wilson -1928 -Thought: Fordham University Quarterly 3 (3):491-498.
- The King is Dead: Studies in the near Eastern Resistance to Hellenism, 334-31 B. C.Moses Hadas &Samuel K. Eddy -1964 -American Journal of Philology 85 (2):204.
- Maintaining Christian virtues and ethos in Christian universities in Ghana: The reality, challenges and the way forward.Peter White &Samuel K. Afrane -2017 -HTS Theological Studies 73 (3):8.Christian universities are established to integrate Christian faith, principles and virtues into their academic programmes with the expectation that through this holistic Christocentric education, students will be well-prepared to serve and to contribute positively to transform society. Although this approach to education is good, it however does not come without the challenge of how to maintain these Christian virtues in light of increasing secularisation and permissiveness in contemporary society. This article examines the realities and challenges of maintaining Christian virtues and (...) ethos in Christian universities in Ghana and recommends some helpful solutions. The study employed eclectic methodology in data gathering and analyses. The research revealed that for a university to be called a Christian university, it must have at its core the vision for Christ-centredness, mission mindedness and discipleship focus. This must also be reflected in the attitude of both students and staff in the way they relate to and manage God’s resources. (shrink)No categories
- Applied Christian Ethics: Foundations, Economic Justice, and Politics.Charles C. Brown,Randall K. Bush,Gary Dorrien,Guyton B. Hammond,Christian T. Iosso,Edward LeRoy Long,John C. Raines,Carol S. Robb,Samuel K. Roberts,Harlan Stelmach,Laura Stivers,Robert L. Stivers,Randall W. Stone,Ronald H. Stone &Matthew Lon Weaver (eds.) -2014 - Lanham, Maryland: Lexington Books.Applied Christian Ethics addresses selected themes in Christian social ethics. Part one shows the roots of contributors in the realist school; part two focuses on different levels of the significance of economics for social justice; and part three deals with both existential experience and government policy in war and peace issues.
- Gender influences on concept structure interrelatedness competence.Harold Harty,Linda Hamrick,Charles Ault &K.Samuel -1987 -Science Education 71 (1):105-115.Export citation Bookmark
- Adverse Childhood Experiences Run Deep: Toxic Early Life Stress, Telomeres, and Mitochondrial DNA Copy Number, the Biological Markers of Cumulative Stress.Kathryn K. Ridout,Mariam Khan &Samuel J. Ridout -2018 -Bioessays 40 (9):1800077.This manuscript reviews recent evidence supporting the utility of telomeres and mitochondrial DNA copy number (mtDNAcn) in detecting the biological impacts of adverse childhood experiences (ACEs) and outlines mechanisms that may mediate the connection between early stress and poor physical and mental health. Critical to interrupting the health sequelae of ACEs such as abuse, neglect, and neighborhood disorder, is the discovery of biomarkers of risk and resilience. The molecular markers of chronic stress exposure, telomere length and mtDNAcn, represent critical biological (...) links between ACEs and poor health outcomes. We examine how telomeres and mtDNAcn may exacerbate health disparities and contribute to the intergenerational transmission of trauma. Finally, we explore how these molecular markers of early stress exposure may help define the role of resilience and develop effective interventions to moderate ACE health risk impact. (shrink)
- A Christian Attitude to the State – An Indian Perspective.Vinay K.Samuel -1991 -Transformation: An International Journal of Holistic Mission Studies 8 (2):6-11.Three traditions have influenced the idea of the state in India – the Hindu Rajah, the Islamic View and the European Secular State. From biblical and theological considerations, Christians must reject the totalism and ego-centrism of modern states and work for greater accountability and decentralised decision-making.No categories
- When pestilence prevails physician responsibilities in epidemics.Samuel J. Huber &Matthew K. Wynia -2004 -American Journal of Bioethics 4 (1):5 – 11.The threat of bioterrorism, the emergence of the SARS epidemic, and a recent focus on professionalism among physicians, present a timely opportunity for a review of, and renewed commitment to, physician obligations to care for patients during epidemics. The professional obligation to care for contagious patients is part of a larger "duty to treat," which historically became accepted when 1) a risk of nosocomial infection was perceived, 2) an organized professional body existed to promote the duty, and 3) the public (...) came to rely on the duty. Physicians' responses to epidemics from the Hippocratic era to the present suggests an evolving acceptance of the professional duty to treat contagious patients, reaching a long-held peak between 1847 and the1950's. There has been some professional retrenchment against this duty to treat in the last 40 years but, we argue, conditions favoring acceptance of the duty are met today. A renewed embrace of physicians' duty to treat patients during epidemics, despite conditions of personal risk, might strengthen medicine's relationship with society, improve society's capacity to prepare for threats such as bioterrorism and new epidemics, and contribute to the development of a more robust and meaningful medical professionalism. (shrink)
- (1 other version)Dynamic Context Generation for Natural Language Understanding: A Multifaceted Knowledge Approach.Samuel W. K. Chan -unknown��We describe a comprehensive framework for text un- derstanding, based on the representation of context. It is designed to serve as a representation of semantics for the full range of in- terpretive and inferential needs of general natural language pro- cessing. Its most distinctive feature is its uniform representation of the various simple and independent linguistic sources that play a role in determining meaning: lexical associations, syntactic re- strictions, case-role expectations, and most importantly, contextual effects. Compositional syntactic structure from a (...) shallow parsing is represented in a neural net-based associative memory, where it then interacts through a Bayesian network with semantic associa- tions and the context or “gist” of the passage carried forward from preceding sentences. Experiments with more than 2000 sentences in different languages are included. (shrink)Export citation Bookmark
- Vorlesungen und Abhandlungen.E. K. Rand,Ludwig Traube,Franz Boll &Samuel Brandt -1922 -American Journal of Philology 43 (1):88.
- Robust inference for matching under rolling enrollment.Samuel D. Pimentel &Amanda K. Glazer -2023 -Journal of Causal Inference 11 (1).Matching in observational studies faces complications when units enroll in treatment on a rolling basis. While each treated unit has a specific time of entry into the study, control units each have many possible comparison, or “pseudo-treatment,” times. Valid inference must account for correlations between repeated measures for a single unit, and researchers must decide how flexibly to match across time and units. We provide three important innovations. First, we introduce a new matched design, GroupMatch with instance replacement, allowing maximum (...) flexibility in control selection. This new design searches over all possible comparison times for each treated-control pairing and is more amenable to analysis than past methods. Second, we propose a block bootstrap approach for inference in matched designs with rolling enrollment and demonstrate that it accounts properly for complex correlations across matched sets in our new design and several other contexts. Third, we develop a falsification test to detect violations of the timepoint agnosticism assumption, which is needed to permit flexible matching across time. We demonstrate the practical value of these tools via simulations and a case study of the impact of short-term injuries on batting performance in major league baseball. (shrink)No categories
- Civilized Shamans: Buddhism in Tibetan Societies.Peter K. Moran &GeoffreySamuel -1995 -Journal of the American Oriental Society 115 (3):506.
- A Review of Berkeley's Theory of Vision, Designed to Show the Unsoundness of That Celebrated Speculation. [REVIEW]Samuel Bailey &Thomas K. Abbott -1953 -British Journal for the Philosophy of Science 4 (13):88-91.Export citation Bookmark
- Does musical enrichment enhance the neural coding of syllables? Neuroscientific interventions and the importance of behavioral data.Samuel Evans,Sophie Meekings,Helen E. Nuttall,Kyle M. Jasmin,Dana Boebinger,Patti Adank &Sophie K. Scott -2014 -Frontiers in Human Neuroscience 8.
- I. the origins of existentialism in prewar France.S. K. Keltner &Samuel J. Julian -2010 - In Alan D. Schrift,The History of Continental Philosophy. London: Routledge. pp. 4--43.
- Education and Society: An Introduction to Education for a Democracy.Samuel Smith,George R. Cressman,Robert K. Speer,George C. Booth,D. Luther Evans &Robert M. Hutchins -1943 -Science and Society 7 (4):374-379.Export citation Bookmark
- What Kind of Popular Participation Does Bioethics Need? Clarifying the Ends of Public Engagement through Randomly Selected Mini-Publics.Jin K. Park,Samuel Bagg &Anna C. F. Lewis -2023 -American Journal of Bioethics 23 (12):82-84.In a recent Target Article Naomi Scheinerman (2023a) has offered an important and compelling call to institutionalize popular participation for heritable genome engineering through the inclusion of...
- Concise Language Promotes Clear Thinking about Cell Shape and Locomotion.Lillian K. Fritz-Laylin,Samuel J. Lord,Mallory Kakley &R. Dyche Mullins -2018 -Bioessays 40 (7):1700225.
- Contextualizing the History of Yoga in GeoffreySamuel’s The Origins of Yoga and Tantra: A Review Symposium. [REVIEW]J. Bronkhorst,C. K. Chapple,L. L. Patton,Geoffrey BrianSamuel,S. R. Sarbacker &V. Wallace -2011 -International Journal of Hindu Studies 15 (3):303-357.No categories
- Where Borders Become Meeting Places: Review of Charles C. Camosy, Peter Singer & Christian Ethics: Beyond Polarization 1. [REVIEW]Samuel Roberto &Ashley K. Fernandes -2013 -American Journal of Bioethics 13 (2):61-62.
- Mind wandering and education: from the classroom to online learning.Karl K. Szpunar,Samuel T. Moulton &Daniel L. Schacter -2013 -Frontiers in Psychology 4.
- New Variant of SARS-CoV-2 Dynamics with Imperfect Vaccine.TayeSamuel Faniran,Aatif Ali,Nawal E. Al-Hazmi,Joshua Kiddy K. Asamoah,Taher A. Nofal &Matthew O. Adewole -2022 -Complexity 2022:1-17.The occurrence of a new strain of SARS-CoV-2 cannot be ruled out. Therefore, this study seeks to investigate the possible effects of a hypothetical imperfect anti-COVID-19 vaccine on the control of not only the first variant of SARS-CoV-2 but also the second variant of SARS-CoV-2. We further examine the rates and a, escape of quarantined infectious individuals from isolation centers. The control R c and basic reproduction numbers R 0 are computed which gives assess to obtain asymptotic stability of disease-free (...) equilibrium point globally and the existence of a unique persistent equilibrium solution. Numerical results reveal that people infected with the second strain who are vaccinated with an imperfect vaccine are under control but the prevalence of the second variant enhances the prevalence of the first variant. Thus, discovering a vaccine that is effective for the prevention of variant 2 is necessary for the control of COVID-19. Numerical results also reveal that increase in the rate at which individuals infected with the first variant escape the isolation center gives rise to the population infected with the first variant and lowers the peak of the population infected with the second variant. This is probably because individuals infected with the second variant appear to be more careful with their lives and get vaccinated more than individuals infected with the first variant. (shrink)
- Symétrons et K-boucles $$\omega $$-stables $$\omega $$-stable symmetric spaces and K-loops.Samuel Zamour -forthcoming -Archive for Mathematical Logic:1-20.Résumé Nous développons la théorie des modèles des K-boucles et des symétrons $$\omega $$ ω -stables. En poursuivant le travail séminal de Poizat, nous établissons notamment une version appropriée du théorème des indécomposables et nous adaptons l’analyse de Lascar à ce contexte.No categories
- The Meaning of Evolution.The First Principles of Evolution.William K. Wright,Samuel Christian Schmucker &S. Herbert -1914 -Philosophical Review 23 (1):86.
- The cultural halo effect: Black and white women rate black and white men.M. J. Intons-Peterson &Arlene K. Samuels -1978 -Bulletin of the Psychonomic Society 11 (5):309-312.
- Normothermic Regional Perfusion, Public Reason, and the Idea of Integrated Organismic Function.Jin K. Park,Samuel N. Doernberg &Robert D. Truog -2024 -American Journal of Bioethics 24 (6):38-40.Two of the lead articles in this issue examine the emerging practice of organ procurement by normothermic regional perfusion (NRP) in terms of whether or not these patients are “dead” at the time t...
- Warfield's new argument for incompatibilism.D. K. Nelkin &Samuel C. Rickless -2002 -Analysis 62 (2):104-107.
- How to solve Blum's paradox.Dana K. Nelkin &Samuel C. Rickless -2001 -Analysis 61 (1):91-94.
- We have nothing left to bury.Abram Brummett,Andrea Thornton,Erica K. Salter &Samuel Deters -2022 -Hastings Center Report 52 (1):12-14.Hastings Center Report, Volume 52, Issue 1, Page 12-14, January/February 2022.
- Teachable Moments: Essays on Experiential Education.David Lovejoy,Walt Anderson,Erin Lotz,Randall Amster,Samuel N. Henrie,K. L. Cook,Susan Hericks,Alison Holmes,Wayne Regina,Liz Faller &David Gilligan (eds.) -2006 - Upa.How do educators better reach their students, better capture their attention and imagination without sacrificing scholarship? Teachable Moments: Essays on Experiential Education examines the pedagogy of Prescott College, a school that has embraced experiential education and been finding success with it for over thirty years. These essays—from scholars in fields as wide ranging as religious studies, environmental science, psychology, dance, literature, adventure education, and peace studies—examine the challenges and, ultimately, the rewards of student-centered education.Export citation Bookmark
- Book Review Section 2. [REVIEW]William H. Goetzmann,William Duffy,Jennings L. Wagoner Jr,Roman A. Bernert,Charles D. Biebel,Dorothy Carrington,Richard G. Durnin,Sheldon Rothblatt,David E. Denton,Hyman Kuritz,Nubuo Shimahara,William Hare,Frederick M. Schultz,Floyd K. Wright,Wiiliam Vaughan,Harold B. Dunkel,Michael B. Mcmahon,Owen E. Pittenger,Stephan Michelson,Kal I. Gezi,Lawrence D. Klein,Yale Mandel &Samuel L. Woodward -1972 -Educational Studies 3 (1):28-44.No categories
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Area Editors:
David Bourget
Gwen Bradford
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Margaret Cameron
David Chalmers
James Chase
Rafael De Clercq
Ezio Di Nucci
Esa Diaz-Leon
Barry Hallen
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Jonathan Ichikawa
Monte Johnson
Michelle Kosch
Øystein Linnebo
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Brandon Look
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Matthew McGrath
Michiru Nagatsu
Susana Nuccetelli
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