The cultural background of the sustainability of the traditional farming system in the Ghouta the oasis of Damascus, Syria.Sameer K.Alhamidi,Mats Gustafsson,Hans Larsson &Per Hillbur -2003 -Agriculture and Human Values 20 (3):231-240.detailsThis paper discusses thepractical impact of a non-materialistic cultureon sustainable farm management.Two elements are discussed: first, how deeplyrooted religion is in this culture; second,the feasibility of using both human knowledgeand experience, so-called tradition and divineguidance in management. Finally, theimplications of the fusion of these twoelements are drawn. The outcome is thecapability of man to integrate ethical valuesinto decisions and actions. This integration,when applied by skilled farmers, leads to amanagement of natural resources in analtruistic fashion and not merely to economicends. Moreover, (...) it makes agriculture meaningfuland sustainable. (shrink)
Combined’ Neck/Back Pain and Psychological Distress/Morbidity Among the Saudi Population: A Cross-Sectional Study.Sameer Al-Ghamdi,Mamdouh M. Shubair,Khadijah Angawi,Jamaan Al-Zahrani,Abdulrahman Ali M. Khormi,Reem Falah Alshammari,Nawaf Safaq Alshammari,Raed Aldahash,Bander Yahya Otayf,Hayat Saleh Al-Zahrani,Manayir Sultan Aleshaiwi &Khaled K. Aldossari -2022 -Frontiers in Psychology 13.detailsBackgroundPsychological distress/morbidity is amongst the primary reason for the cause of pain at multiple sites, its progression, and recovery. Though still not very clear if physical pain in the neck or the back may predict psychological morbidities or not. Thus, we investigated the association between combined neck or back pain and psychological distress/morbidity.MethodsA cross-sectional study was conducted in Al-Kharj, Saudi Arabia, including 1,003 individuals. The questionnaire comprised of General Health Questionnaire-12 and some questions about neck and back pain. Data analysis (...) was done using statistical software SPSS version 26.0.ResultsThe results of the multivariate analysis revealed a significant positive association between neck/back pain status and total GHQ score. Having neck/back pain had almost a 2.5 times greater risk of psychological distress/morbidity. Further, females were more likely to have a higher risk of psychological distress/morbidity than males while adjusting for sociodemographic and clinical characteristics.ConclusionThe combination of neck and back pain was significantly associated with the Saudi population’s psychological problems. Therefore, the Saudi government needs to devise high-risk strategies and allocate adequate resources to the cause so that at-risk people can be shielded from the adverse complications arising from this condition in the long run. (shrink)
Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury.Joshua K. Wong,Günther Deuschl,Robin Wolke,Hagai Bergman,Muthuraman Muthuraman,Sergiu Groppa,Sameer A. Sheth,Helen M. Bronte-Stewart,Kevin B. Wilkins,Matthew N. Petrucci,Emilia Lambert,Yasmine Kehnemouyi,Philip A. Starr,Simon Little,Juan Anso,Ro’ee Gilron,Lawrence Poree,Giridhar P. Kalamangalam,Gregory A. Worrell,Kai J. Miller,Nicholas D. Schiff,Christopher R. Butson,Jaimie M. Henderson,Jack W. Judy,Adolfo Ramirez-Zamora,Kelly D. Foote,Peter A. Silburn,Luming Li,Genko Oyama,Hikaru Kamo,Satoko Sekimoto,Nobutaka Hattori,James J. Giordano,Diane DiEuliis,John R. Shook,Darin D. Doughtery,Alik S. Widge,Helen S. Mayberg,Jungho Cha,Kisueng Choi,Stephen Heisig,Mosadolu Obatusin,Enrico Opri,Scott B. Kaufman,Prasad Shirvalkar,Christopher J. Rozell,Sankaraleengam Alagapan,Robert S. Raike,Hemant Bokil,David Green &Michael S. Okun -2022 -Frontiers in Human Neuroscience 16.detailsDBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers can freely discuss current and emerging deep brain stimulation technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in (...) its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury. (shrink)
PELP: Accounting for Missing Data in Neural Time Series by Periodic Estimation of Lost Packets.Evan M. Dastin-van Rijn,Nicole R. Provenza,Gregory S. Vogt,Michelle Avendano-Ortega,Sameer A. Sheth,Wayne K. Goodman,Matthew T. Harrison &David A. Borton -2022 -Frontiers in Human Neuroscience 16.detailsRecent advances in wireless data transmission technology have the potential to revolutionize clinical neuroscience. Today sensing-capable electrical stimulators, known as “bidirectional devices”, are used to acquire chronic brain activity from humans in natural environments. However, with wireless transmission come potential failures in data transmission, and not all available devices correctly account for missing data or provide precise timing for when data losses occur. Our inability to precisely reconstruct time-domain neural signals makes it difficult to apply subsequent neural signal processing techniques (...) and analyses. Here, our goal was to accurately reconstruct time-domain neural signals impacted by data loss during wireless transmission. Towards this end, we developed a method termed Periodic Estimation of Lost Packets. PELP leverages the highly periodic nature of stimulation artifacts to precisely determine when data losses occur. Using simulated stimulation waveforms added to human EEG data, we show that PELP is robust to a range of stimulation waveforms and noise characteristics. Then, we applied PELP to local field potential recordings collected using an implantable, bidirectional DBS platform operating at various telemetry bandwidths. By effectively accounting for the timing of missing data, PELP enables the analysis of neural time series data collected via wireless transmission—a prerequisite for better understanding the brain-behavior relationships underlying neurological and psychiatric disorders. (shrink)
Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.Vinata Vedam-Mai,Karl Deisseroth,James Giordano,Gabriel Lazaro-Munoz,Winston Chiong,Nanthia Suthana,Jean-Philippe Langevin,Jay Gill,Wayne Goodman,Nicole R. Provenza,Casey H. Halpern,Rajat S. Shivacharan,Tricia N. Cunningham,Sameer A. Sheth,Nader Pouratian,Katherine W. Scangos,Helen S. Mayberg,Andreas Horn,Kara A. Johnson,Christopher R. Butson,Ro’ee Gilron,Coralie de Hemptinne,Robert Wilt,Maria Yaroshinsky,Simon Little,Philip Starr,Greg Worrell,Prasad Shirvalkar,Edward Chang,Jens Volkmann,Muthuraman Muthuraman,Sergiu Groppa,Andrea A. Kühn,Luming Li,Matthew Johnson,Kevin J. Otto,Robert Raike,Steve Goetz,Chengyuan Wu,Peter Silburn,Binith Cheeran,Yagna J. Pathak,Mahsa Malekmohammadi,Aysegul Gunduz,Joshua K. Wong,Stephanie Cernera,Aparna Wagle Shukla,Adolfo Ramirez-Zamora,Wissam Deeb,Addie Patterson,Kelly D. Foote &Michael S. Okun -2021 -Frontiers in Human Neuroscience 15:644593.detailsWe estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. (...) The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on September 1 and 2, 2020 (Zoom Video Communications) due to restrictions related to the COVID-19 pandemic. The meeting focused on advances in: (1) optogenetics as a tool for comprehending neurobiology of diseases and on optogenetically-inspired DBS, (2) cutting edge of emerging DBS technologies, (3) ethical issues affecting DBS research and access to care, (4) neuromodulatory approaches for depression, (5) advancing novel hardware, software and imaging methodologies, (6) use of neurophysiological signals in adaptive neurostimulation, and (7) use of more advanced technologies to improve DBS clinical outcomes. There were 178 attendees who participated in a DBS Think Tank survey, which revealed the expansion of DBS into several indications such as obesity, post-traumatic stress disorder, addiction and Alzheimer’s disease. This proceedings summarizes the advances discussed at the Eighth Annual DBS Think Tank. (shrink)
Artifact characterization and mitigation techniques during concurrent sensing and stimulation using bidirectional deep brain stimulation platforms.Michaela E. Alarie,Nicole R. Provenza,Michelle Avendano-Ortega,Sarah A. McKay,Ayan S. Waite,Raissa K. Mathura,Jeffrey A. Herron,Sameer A. Sheth,David A. Borton &Wayne K. Goodman -2022 -Frontiers in Human Neuroscience 16:1016379.detailsBidirectional deep brain stimulation (DBS) platforms have enabled a surge in hours of recordings in naturalistic environments, allowing further insight into neurological and psychiatric disease states. However, high amplitude, high frequency stimulation generates artifacts that contaminate neural signals and hinder our ability to interpret the data. This is especially true in psychiatric disorders, for which high amplitude stimulation is commonly applied to deep brain structures where the native neural activity is miniscule in comparison. Here, we characterized artifact sources in recordings (...) from a bidirectional DBS platform, the Medtronic Summit RC + S, with the goal of optimizing recording configurations to improve signal to noise ratio (SNR). Data were collected from three subjects in a clinical trial of DBS for obsessive-compulsive disorder. Stimulation was provided bilaterally to the ventral capsule/ventral striatum (VC/VS) using two independent implantable neurostimulators. We first manipulated DBS amplitude within safe limits (2–5.3 mA) to characterize the impact of stimulation artifacts on neural recordings. We found that high amplitude stimulation produces slew overflow, defined as exceeding the rate of change that the analog to digital converter can accurately measure. Overflow led to expanded spectral distortion of the stimulation artifact, with a six fold increase in the bandwidth of the 150.6 Hz stimulation artifact from 147–153 to 140–180 Hz. By increasing sense blank values during high amplitude stimulation, we reduced overflow by as much as 30% and improved artifact distortion, reducing the bandwidth from 140–180 Hz artifact to 147–153 Hz. We also identified artifacts that shifted in frequency through modulation of telemetry parameters. We found that telemetry ratio changes led to predictable shifts in the center-frequencies of the associated artifacts, allowing us to proactively shift the artifacts outside of our frequency range of interest. Overall, the artifact characterization methods and results described here enable increased data interpretability and unconstrained biomarker exploration using data collected from bidirectional DBS devices. (shrink)
Wahrheit und Bedeutung: Objektive Geltung im moraltheologischen Diskurs.K. Demmer -2000 -Gregorianum 81 (1):59-99.detailsL'article est consacré à la recherche sur le statut objectif de la vérité morale. L'A. étudie les divers types de vérités et les pensées philosophiques modernes sur celles-ci, pensées présentes dans le champ théologique contemporain. Il étudie ensuite la théologie morale catholique sur la décision morale et la norme de conduite.
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Nietzsche and the eternal return of sacrifice.K. D. -2003 -Research in Phenomenology 33 (1):167-185.detailsIn the work of Nietzsche, sacrifice can only sacrifice itself over and over (in an eternal return of the same) because what it seeks to overcome (the nihilistic revelation of truth that sublates sacrifice's negation) makes this sacrifice of itself both necessary and useless. The truth is eternally postponed in a necessary sacrificial gesture that can only sacrifice itself, thereby rendering itself useless. In the attempt to step beyond nihilism, that is, in the attempt to negate (or sacrifice) nihilism, one (...) repeats the negation characteristic of nihilism. One becomes inextricably implicated in the move of nihilistic sacrifice. The sacrifice of the sacrifice characteristic of nihilism, that is, the sacrifice of sacrifice, can only take place as (perform itself as) the impossibility (or eternally postponed possibility) of its realization. One, therefore, produces or performs an interminable step/not beyond, an incessant step beyond that eternally returns. (shrink)
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Filosofskie izmerenii︠a︡ politiki, diplomatii i kulʹtury: v pi︠a︡ti tomakh.K. M. Dolgov -2006 - Moskva: Nauchnai︠a︡ kniga.detailst. 1. Filosofii͡a : samosoznanie cheloveka i obshchestva -- t. 2. Politika i istoriosofii͡a -- t. 3. Politika i diplomatii͡a -- t. 4. Kulʹtura i sovremennostʹ -- t. 5. Zapadnoevropeĭskai͡a filosofii͡a, politika i kulʹtura: problemy i perspektivy.
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Herodotus Historiae: Volume Ii Books V-Ix.K. Hude (ed.) -1927 - Oxford University Press UK.detailsHerodotus of Halicarnassus was an Ionian traveler and storyteller who lived in the 5th century BC. He is almost exclusively known for writing The Histories, a collection of "inquiries" about the places and peoples he encountered during his wide-ranging travels around the Mediterranean littoral and into the Mesopotamia.
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