Results for 'P. Nicolas Ledoux'
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- Entretien à propos de Ludovic Chemarin©.Damien Beguet &P.NicolasLedoux -2015 -Multitudes 57 (3):102-109.À propos de Ludovic Chemarin© est un entretien entre Damien Beguet, Perrine Lacroix et P.NicolasLedoux réalisé pour la première apparition public du projet Ludovic Chemarin© à La BF15 (Lyon) en 2011. Cette discussion entre la responsable du lieu et les deux artistes permet de mieux cerner les enjeux conceptuels et formels d’un dispositif complexe et critique. Ce texte est un témoignage mais il a été depuis mis en forme et présenté régulièrement sous la forme d’affiches dans (...) le cadre d’expositions aux côté de documents (contrats, produits dérivés) et de pièces de l’artiste. Il fait œuvre et participe au brouillage de l’entreprise Ludovic Chemarin©. (shrink)
- Introdução ao Existencialismo.Nicola Abbagnano,João Lopes Alves,P. Teófilo Urdanoz &Maurice Cranston -1965 -Revista Portuguesa de Filosofia 21 (1):100-103.No categoriesExport citation
Bookmark - Pivoting the Role of Government in the Business and Society Interface: A Stakeholder Perspective.Nicolas M. Dahan,Jonathan P. Doh &Jonathan D. Raelin -2015 -Journal of Business Ethics 131 (3):665-680.The growing popularization of stakeholder theory among management scholars has offered a useful framework for understanding the multiple and interdependent roles of government and business in an increasingly challenging political and regulatory environment. Despite this trend, attention to the role and responsibility of government to protect citizen rights has been limited. To the two traditional stakeholder theory views of government where the focal organization remains the firm, we propose to add two views by pivoting the government’s place and making it (...) the focal organization. We thus describe governments as serving four roles in the business–government–society nexus. For each role, we analyze typical governmental activities/behaviors, relationships with firms’ stakeholders, as well as the challenges and limits to these roles. We also focus on the central notion of salience amplification, as a means of checks and balances across stakeholders in order to safeguard citizen rights and reveal the greater good. (shrink)
- Learning representations in a gated prefrontal cortex model of dynamic task switching.Nicolas P. Rougier &Randall C. O'Reilly -2002 -Cognitive Science 26 (4):503-520.The prefrontal cortex is widely believed to play an important role in facilitating people's ability to switch performance between different tasks. We present a biologically‐based computational model of prefrontal cortex (PFC) that explains its role in task switching in terms of the greater flexibility conferred by activation‐based working memory representations in PFC, as compared with more slowly adapting weight‐based memory mechanisms. Specifically we show that PFC representations can be rapidly updated when a task switches via a dynamic gating mechanism based (...) on a temporal‐differences reward‐prediction learning mechanism. Unlike prior models of this type, the present model develops all of its internal representations via learning mechanisms as shaped by the demands of continuous periodic task switching. This advance opens up a new domain of research into the interactions between working memory task demands and the representations that develop to meet them. Results on a version of the Wisconsin card sorting task are presented for the full model and a number of comparison networks that test the importance of various model features. Furthermore, we show that a lesioned model produces perseverative errors like those seen in frontal patients. (shrink)No categories
- Assessing the Thin Regulation of Consumer-Facing Health Technologies.Nicolas P. Terry -2020 -Journal of Law, Medicine and Ethics 48 (S1):94-102.This article addresses the data protection and product safety regulatory models currently applied to consumer-facing health technologies. It explains how the design and structures of existing data protection and safety regulation in the U.S. have resulted in exceptionally thin protection for the users of consumer-facing devices and products that rely on or that facilitate consumer collection or aggregation of health and wellness data. It also examines some appealing legislative alternatives to the current thin model used in the U.S. and suggests (...) a framework for prioritizing ameliorative regulation. To better understand existing regulatory models, their deficiencies, and how they should be reformed, the article employs an analytical model describing these regulatory systems across two axes. The vertical axis describes the quantity or depth of regulation, such as, for example, the strictness of the rules imposed by the regulatory model. The horizontal axis describes the reach of the regulation, the behaviors, products, or industries to which the regulation applies. (shrink)
- Short Duration Repetitive Transcranial Electrical Stimulation During Sleep Enhances Declarative Memory of Facts.Nicola Cellini,Renee E. Shimizu,Patrick M. Connolly,Diana M. Armstrong,Lexus T. Hernandez,Anthony G. Polakiewicz,Rolando Estrada,Mario Aguilar-Simon,Michael P. Weisend,Sara C. Mednick &Stephen B. Simons -2019 -Frontiers in Human Neuroscience 13.
- Faw, Bill, 83 Flach, Rudiger, 620.Nicolas Franck,Gisa Aschersleben,Talis Bachmann,Simona F. Baracaia,Barbara H. Basden,David R. Basden,R. P. Behrendt,Sarah-Jayne Blakemore,Richard A. Bryant &Alfred Buck -2003 -Consciousness and Cognition 12:784-785.No categoriesExport citation Bookmark
- More Than One Binary.Nicolas P. Terry -2010 -American Journal of Bioethics 10 (9):31-32.
- Communauté des grands esprits.M. P.Nicolas -1945 - Paris,: Fasquelle.Export citation Bookmark
- De Nietzsche à Hitler.M. P.Nicolas -1936 - Paris,: Fasquelle.Export citation Bookmark
- Art and Science: A Philosophical Sketch of Their Historical Complexity and Codependence.Nicolas J. Bullot,William P. Seeley &Stephen Davies -2017 -Journal of Aesthetics and Art Criticism 75 (4):453-463.To analyze the relations between art and science, philosophers and historians have developed different lines of inquiry. A first type of inquiry considers how artistic and scientific practices have interacted over human history. Another project aims to determine the contributions that scientific research can make to our understanding of art, including the contributions that cognitive science can make to philosophical questions about the nature of art. We rely on contributions made to these projects in order to demonstrate that art and (...) science are codependent phenomena. Specifically, we explore the codependence of art and science in the context of a historical analysis of their interactions and in the context of contemporary debates on the cognitive science of art. (shrink)
- Remote Agent: to boldly go where no AI system has gone before.Nicola Muscettola,P. Pandurang Nayak,Barney Pell &Brian C. Williams -1998 -Artificial Intelligence 103 (1-2):5-47.
- Playing with machines: Using machine learning to understand automated copyright enforcement at scale.Nicolas P. Suzor &Joanne E. Gray -2020 -Big Data and Society 7 (1).This article presents the results of methodological experimentation that utilises machine learning to investigate automated copyright enforcement on YouTube. Using a dataset of 76.7 million YouTube videos, we explore how digital and computational methods can be leveraged to better understand content moderation and copyright enforcement at a large scale.We used the BERT language model to train a machine learning classifier to identify videos in categories that reflect ongoing controversies in copyright takedowns. We use this to explore, in a granular way, (...) how copyright is enforced on YouTube, using both statistical methods and qualitative analysis of our categorised dataset. We provide a large-scale systematic analysis of removals rates from Content ID’s automated detection system and the largely automated, text search based, Digital Millennium Copyright Act notice and takedown system. These are complex systems that are often difficult to analyse, and YouTube only makes available data at high levels of abstraction. Our analysis provides a comparison of different types of automation in content moderation, and we show how these different systems play out across different categories of content. We hope that this work provides a methodological base for continued experimentation with the use of digital and computational methods to enable large-scale analysis of the operation of automated systems. (shrink)No categories
- At least some electrophysiological and behavioural data cannot be reconciled with the planning–control model.P. Paolo Battaglini,Paolo Bernardis &Nicola Bruno -2004 -Behavioral and Brain Sciences 27 (1):24-25.The planning/control distinction is an important tool in the study of sensorimotor transformations. However, published data from our laboratories suggest that, contrary to what is predicted by the proposed model, (1) structures in the superior parietal lobe of both monkeys and humans can be involved in movement planning; and (2) fast pointing actions can be immune to visual illusions even if they are performed without visual feedback. The planning–control model as proposed by Glover is almost certainly too schematic.
- OBO Foundry in 2021: Operationalizing Open Data Principles to Evaluate Ontologies.Rebecca C. Jackson,Nicolas Matentzoglu,James A. Overton,Randi Vita,James P. Balhoff,Pier Luigi Buttigieg,Seth Carbon,Melanie Courtot,Alexander D. Diehl,Damion Dooley,William Duncan,Nomi L. Harris,Melissa A. Haendel,Suzanna E. Lewis,Darren A. Natale,David Osumi-Sutherland,Alan Ruttenberg,Lynn M. Schriml,Barry Smith,Christian J. Stoeckert,Nicole A. Vasilevsky,Ramona L. Walls,Jie Zheng,Christopher J. Mungall &Bjoern Peters -2021 -BioaRxiv.Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)
- Size coding of alternative responses is sufficient to induce a potentiation effect with manipulable objects.Loïc P. Heurley,Thibaut Brouillet,Alexandre Coutté &Nicolas Morgado -2020 -Cognition 205 (C):104377.
- Emotional impacts of participation in an Australian national survey on mental health-related discrimination.Denise P. W. Tan,Amy J. Morgan,Anthony F. Jorm &Nicola J. Reavley -2019 -Ethics and Behavior 29 (6):438-458.Institutional Review Boards have expressed concern that research into sensitive topics such as mental disorder will cause participants undue distress. This study investigated the emotional responses of 5,220 Australians to a survey on mental-health-related discrimination. Participants were interviewed about their mental health and experiences of discrimination across 10 life domains and then the emotional impacts of the survey. Results suggested that a minority experienced a negative reaction in contrast to 88% reporting positive experiences. A mental health problem was associated with (...) both negative and positive reactions. (shrink)
- Resolving the impasse on predictive genetic testing in minors: will more evidence be the solution?Stephen P. Robertson &Nicola Kerruish -2012 -Journal of Medical Ethics 38 (9):525-526.
- On fair selection in the presence of implicit and differential variance.Vitalii Emelianov,Nicolas Gast,Krishna P. Gummadi &Patrick Loiseau -2022 -Artificial Intelligence 302 (C):103609.
- Investigating low-frequency dielectric properties of a composite using the distribution of relaxation times technique.Enis Tuncer,Nicola Bowler,I. J. Youngs &K. P. Lymer -2006 -Philosophical Magazine 86 (16):2359-2369.No categories
- Motor Skill Acquisition and Retention after Somatosensory Electrical Stimulation in Healthy Humans.Menno P. Veldman,Inge Zijdewind,Nicola A. Maffiuletti &Tibor Hortobágyi -2016 -Frontiers in Human Neuroscience 10.
- The Goal Circuit Model: A Hierarchical Multi‐Route Model of the Acquisition and Control of Routine Sequential Action in Humans.Richard P. Cooper,Nicolas Ruh &Denis Mareschal -2014 -Cognitive Science 38 (2):244-274.Human control of action in routine situations involves a flexible interplay between (a) task-dependent serial ordering constraints; (b) top-down, or intentional, control processes; and (c) bottom-up, or environmentally triggered, affordances. In addition, the interaction between these influences is modulated by learning mechanisms that, over time, appear to reduce the need for top-down control processes while still allowing those processes to intervene at any point if necessary or if desired. We present a model of the acquisition and control of goal-directed action (...) that goes beyond existing models by operationalizing an interface between two putative systems—a routine and a non-routine system—thereby demonstrating how explicitly represented goals can interact with the emergent task representations that develop through learning in the routine system. The gradual emergence of task representations offers an explanation for the transfer of control with experience from the non-routine goal-based system to the routine system. At the same time it allows action selection to be sensitive both to environmental triggers and to biasing from multiple levels within the goal system. (shrink)
- Can jackdaws select individuals based on their ability to help?Auguste M. P. vonBayern,Nicola S. Clayton &Nathan J. Emery -2011 -Interaction Studies 12 (2):262-280.
- Living the Love Story: Catholic Morality in the Modern World by Christopher P. Klofft.AllisonLeDoux -2010 -The National Catholic Bioethics Quarterly 10 (1):198-201.
- (1 other version)...Esquisse d'un tableau historique des progrès de l'esprit humain.Jean-Antoine-Nicolas de Caritat Condorcet,P. Daunou &Marie-Louise-Sophie de Grouchy Condorcet -1933 - Paris,: Boivin et cie. Edited by Oliver H. Prior.No categories
- Afterlife: the post-research affect and effect of software.Nicolas E. Gold,Ian Lawson &Neil P. Oxtoby -2023 -Research Ethics 19 (4):433-448.Software plays an important role in contemporary research. Aside from its use for administering traditional instruments like surveys and in data analysis, the widespread use of mobile and web apps for social, medical and lifestyle engagement has led to software becoming a research intervention in its own right. For example, it is not unusual to find apps being studied for their utility as interventions in health and social life. Since the software may persist in use beyond the life of an (...) investigation, this raises questions as to the extent of ethical duties for researchers involved in its production and/or study towards the participants involved. Key factors identified include the extent of affect created by the software, the effect it has on a participant’s life, the length of investigation, cost of maintenance and participant agency. In this article we discuss the issues raised in such situations, considering them in the context of post-research duties of care and suggesting strategies to balance the burden on researchers with the need for ongoing participant support. (shrink)
- La vision nouvelle de la société dans l’Encyclopédie méthodique. Volume V.J. Boulad-Ayoub,P. Caye,M. Groult,Sylviane Albertan-Coppola &Nicolas Sylvestre Bergier -2022 - Les Presses de l’Université de Laval.Fille de l’Encyclopédie (1751-1772, 28 vol.) de Diderot et d’Alembert, l’Encyclopédie méthodique (1782-1832, 212 vol.) de Panckoucke conserve la palme du gigantisme. Si la Révolution Française pendant laquelle est publié le Dictionnaire de Théologie, n’a rien changé ni aboli dans le domaine de la pensée, elle a changé les conditions d’exercice pour les directeurs scientifiques. De surcroit en synthétisant ce moment particulier des savoirs liant mots et choses, la Méthodique représente un chainon incontournable entre l’épistémé des Lumières et celle du (...) xixè siècle. Alors que l’Encyclopédie dans un Système figuré des connaissances humaines construisait un ordre encyclopédique à partir des trois facultés de l’entendement humain (mémoire, raison, imagination), Panckoucke, qui craint la polémique sur les renvois, réoriente cet ordre. Il découpe chaque article et organise des listes de matières à partir de l’Encyclopédie. L’ordre des matières ne vise que les choses de la science qui, dans chaque Dictionnaire, seront détaillées au mieux. Enfin pour conduire le lecteur dans la connaissance, une table analytique propose un ordre de lecture transformant le dictionnaire en traité didactique. Le Dictionnaire de Théologie relève un autre aspect de la pensée philosophique du Système figuré, à savoir, une séparation de la Théologie ou Science de Dieu, des deux autres sciences que sont la Science de l’homme et la Science de la nature. Le progrès va se faire avec ces deux Sciences, sans la Théologie. Bergier revient sur cette séparation traduite par l’évincement des théologiens de l’entreprise encyclopédique des Lumières. Il remplit alors parfaitement le rôle demandé par Panckoucke de corriger et de compléter celle que ce dernier appelle la « première Encyclopédie» voulant être le directeur de la seconde Encyclopédie. (shrink)No categories
- Cognitive adaptations of social bonding in birds.Nathan J. Emery,Amanda M. Seed,Auguste M. P. Von Bayern & Clayton &S. Nicola -2007 - In Nathan Emery, Nicola Clayton & Chris Frith,Social Intelligence: From Brain to Culture. Oxford University Press.
- Robotics and Well-Being.Maria Isabel Aldinhas Ferreira,Ana S. Aníbal,P. Beardsley,Selmer Bringsjord,Paulo S. Carvalho,Raja Chatila,Vladimir Estivill-Castro,Nicola Fabiano,Sarah R. Fletcher,Rodolphe Gelin,Rikhiya Ghosh,Naveen Sundar Govindarajulu,John C. Havens,Teegan L. Johnson,Endre E. Kadar,Jon Larreina,Pedro U. Lima,Stuti Thapa Magar,Bertram F. Malle,André Martins,Michael P. Musielewicz,A. Mylaeus,Matthew Peveler,Matthias Scheutz,João Silva Sequeira,R. Siegwart,B. Tranter &A. Vempati (eds.) -2019 - Springer Verlag.This book highlights some of the most pressing safety, ethical, legal and societal issues related to the diverse contexts in which robotic technologies apply. Focusing on the essential concept of well-being, it addresses topics that are fundamental not only for research, but also for industry and end-users, discussing the challenges in a wide variety of applications, including domestic robots, autonomous manufacturing, personal care robots and drones.
- Does a smartphone on the desk drain our brain? No evidence of cognitive costs due to smartphone presence in a short-term and prospective memory task.Matthias Hartmann,Corinna S. Martarelli,Thomas P. Reber &Nicolas Rothen -2020 -Consciousness and Cognition 86:103033.
- Chantal reynier, l'épitre aux éphésiens (commentaire biblique: Nouveau testament 10), Paris, Cerf, 2004, 236 P.Nicolas Cochand -2005 -Revue de Théologie Et de Philosophie 137:419.No categoriesExport citation Bookmark
- Clinical ethics case consultation in a university department of cardiology and intensive care: a descriptive evaluation of consultation protocols.Michel Noutsias,Daniel Sedding,Jochen Dutzmann,Henning Rosenau,Kim P. Linoh,Nicolas Heirich,Stephan Nadolny,Jan Schildmann &Andre Nowak -2021 -BMC Medical Ethics 22 (1):1-12.BackgroundClinical ethics case consultations (CECCs) provide a structured approach in situations of ethical uncertainty or conflicts. There have been increasing calls in recent years to assess the quality of CECCs by means of empirical research. This study provides detailed data of a descriptive quantitative and qualitative evaluation of a CECC service in a department of cardiology and intensive care at a German university hospital.MethodsSemi-structured document analysis of CECCs was conducted in the period of November 1, 2018, to May 31, 2020. (...) All documents were analysed by two researchers independently.ResultsTwenty-four CECCs were requested within the study period, of which most (n = 22; 92%) had been initiated by physicians of the department. The patients were an average of 79 years old (R: 43–96), and 14 (58%) patients were female. The median length of stay prior to request was 12.5 days (R: 1–65 days). The most frequent diagnoses (several diagnoses possible) were cardiology-related (n = 29), followed by sepsis (n = 11) and cancer (n = 6). Twenty patients lacked decisional capacity. The main reason for a CECC request was uncertainty about the balancing of potential benefit and harm related to the medically indicated treatment (n = 18). Further reasons included differing views regarding the best individual treatment option between health professionals and patients (n = 3) or between different team members (n = 3). Consensus between participants could be reached in 18 (75%) consultations. The implementation of a disease specific treatment intervention was recommended in five cases. Palliative care and limitation of further disease specific interventions was recommended in 12 cases.ConclusionsTo the best of our knowledge, this is the first in-depth evaluation of a CECC service set up for an academic department of cardiology and intensive medical care. Patient characteristics and the issues deliberated during CECC provide a starting point for the development and testing of more tailored clinical ethics support services and research on CECC outcomes. (shrink)No categories
- The liberal arts : inheritances and conceptual frameworks.E. M. Gasper Giles,Nicola Polloni Sigbjørn Olsen Sønnesyn,Jack Neil Lewis &P. Cunningham -2019 - In John Coleman, Jack Cunningham, Nader El-Bizri, Giles E. M. Gasper, Joshua S. Harvey, Margaret Healy-Varley, David M. Howard, Neil Timothy Lewis, Anne Lawrence-Mathers, Tom McLeish, Cecilia Panti, Nicola Polloni, Clive R. Siviour, Hannah E. Smithson, Sigbjørn Olsen Sønnesyn, David Thomson, Rebekah C. White & Robert Grosseteste,The scientific works of Robert Grosseteste. Oxford: Oxford University Press.No categoriesExport citation Bookmark
- Juan Carlos Pita Castro, Devenir artiste, une enquête biographique. Paris, L’Harmattan, coll. Logiques sociales, 308 p.Nicolas Roux -2014 -Temporalités 20.Les travaux sociologiques ne manquent pas pour souligner la précarité de l’emploi des artistes et de leur carrière. Un questionnement émerge de ce constat : pourquoi des individus souhaitent-ils s’engager dans un secteur d’activité marqué du sceau de l’incertitude? Pourquoi et comment certains persistent-ils malgré les épreuves? En relatant les récits d’artistes en devenir, l’ouvrage de J-C. Pita Castro apporte un éclairage complémentaire au travail de L. Sibaud, qui analysait conjointement..No categories
- Human Sensory LTP Predicts Memory Performance and Is Modulated by the BDNF Val66Met Polymorphism.Meg J. Spriggs,Chris S. Thompson,David Moreau,Nicolas A. McNair,C. Carolyn Wu,Yvette N. Lamb,Nicole S. McKay,Rohan O. C. King,Ushtana Antia,Andrew N. Shelling,Jeff P. Hamm,Timothy J. Teyler,Bruce R. Russell,Karen E. Waldie &Ian J. Kirk -2019 -Frontiers in Human Neuroscience 13.
- Nicolas Malebranche: Dialogues on Metaphysics and on Religion.P. Riley -1999 -British Journal for the History of Philosophy 7 (1):167-170.Export citation Bookmark
- Traité de l'amour de Dieu. Trois lettres et réponse générale au R.P. Lamy.Nicolas Malebranche,André Robinet &Centre National de la Recherche Scientifique -1958 - J. Vrin.No categories
- Abbagnano Nicola, "problemi di sociologia".P. Filiasi Carcano -1961 -Giornale Critico Della Filosofia Italiana 15:259.No categoriesExport citation Bookmark
- Thierry de Chartres etNicolas de Cues.P. Duhem -1909 -Revue des Sciences Philosophiques Et Théologiques 3:525-531.No categoriesExport citation Bookmark
- P. Vandevelde (ed.), Epistemology, Archaeology, Ethics: Current Investigations of Husserl's Corpus.Nicolas Fernando de Warren -forthcoming -Notre Dame Philosophical Reviews.
- J ean -p ierre M arquis . From a geometrical point of view: A study of the history and philosophy of category theory.Molly Kao,Nicolas Fillion &John Bell -2010 -Philosophia Mathematica 18 (2):227-234.(No abstract is available for this citation).
- Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases. [REVIEW]Brian T. Helfand,Kimberly A. Roehl,Phillip R. Cooper,Barry B. McGuire,Liesel M. Fitzgerald,Geraldine Cancel-Tassin,Jean-Nicolas Cornu,Scott Bauer,Erin L. Van Blarigan,Xin Chen,David Duggan,Elaine A. Ostrander,Mary Gwo-Shu,Zuo-Feng Zhang,Shen-Chih Chang,Somee Jeong,Elizabeth T. H. Fontham,Gary Smith,James L. Mohler,Sonja I. Berndt,Shannon K. McDonnell,Rick Kittles,Benjamin A. Rybicki,Matthew Freedman,Philip W. Kantoff,Mark Pomerantz,Joan P. Breyer,Jeffrey R. Smith,Timothy R. Rebbeck,Dan Mercola,William B. Isaacs,Fredrick Wiklund,Olivier Cussenot,Stephen N. Thibodeau,Daniel J. Schaid,Lisa Cannon-Albright,Kathleen A. Cooney,Stephen J. Chanock,Janet L. Stanford,June M. Chan,John Witte,Jianfeng Xu,Jeannette T. Bensen,Jack A. Taylor &William J. Catalona -unknown© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)No categories
- Libertad, resentimiento y pandemia.Nicolás Alles -2021 -Cuadernos Filosóficos / Segunda Época 18.In this article I will analyze the conception of moral responsibility proposed by P.F. Strawson in "Freedom and Resentment". I will argue that this conception is relevant for thinking about some aspects of the current COVID-19 pandemic, in particular, those related to cooperation between individuals and its affective dimension.No categories
- Richard schaeffler, le langage de la prière. Essai d'analyse philosophique, trad. Fr. Clara vasseur, Paris, Cerf, 2003, 150 P. [REVIEW]Nicolas Zufferey -2005 -Revue de Théologie Et de Philosophie 137:89.No categoriesExport citation Bookmark
- Religiis pʻilosopʻia =.Irakli Bračuli,Nicolae Dură &Anastasia Zakʻariaże (eds.) -2015 - Tʻbilisi: Universitetis gamomcʻemloca.No categories
- Closed-Loop Targeted Memory Reactivation during Sleep Improves Spatial Navigation.Renee E. Shimizu,Patrick M. Connolly,Nicola Cellini,Diana M. Armstrong,Lexus T. Hernandez,Rolando Estrada,Mario Aguilar,Michael P. Weisend,Sara C. Mednick &Stephen B. Simons -2018 -Frontiers in Human Neuroscience 12.
- Wilson and Jungner Revisited: Are Screening Criteria Fit for the 21st Century?Elena Schnabel-Besson,Ulrike Mütze,Nicola Dikow,Friederike Hörster,Marina A. Morath,Karla Alex,Heiko Brennenstuhl,Sascha Settegast,Jürgen G. Okun,Christian P. Schaaf,Eva C. Winkler &Stefan Kölker -2024 -International Journal of Neonatal Screening 10 (3(62)):1-15.Driven by technological innovations, newborn screening (NBS) panels have been expanded and the development of genomic NBS pilot programs is rapidly progressing. Decisions on disease selection for NBS are still based on the Wilson and Jungner (WJ) criteria published in 1968. Despite this uniform reference, interpretation of the WJ criteria and actual disease selection for NBS programs are highly variable. A systematic literature search [PubMED search “Wilson” AND “Jungner”; last search 16.07.22] was performed to evaluate the applicability of the WJ (...) criteria for current and future NBS programs and the need for adaptation. By at least two reviewers, 105 publications (systematic literature search, N = 77; manual search, N = 28) were screened for relevant content and, finally, 38 publications were evaluated. Limited by the study design of qualitative text analysis, no statistical evaluation was performed, but a structured collection of reported aspects of criticism and proposed improvements was instead collated. This revealed a set of general limitations of the WJ criteria, such as imprecise terminology, lack of measurability and objectivity, missing pediatric focus, and absent guidance on program management. Furthermore, it unraveled specific aspects of criticism on clinical, diagnostic, therapeutic, and economical aspects. A major obstacle was found to be the incompletely understood natural history and phenotypic diversity of rare diseases prior to NBS implementation, resulting in uncertainty about case definition, risk stratification, and indications for treatment. This gap could be closed through the systematic collection and evaluation of real-world evidence on the quality, safety, and (cost-)effectiveness of NBS, as well as the long-term benefits experienced by screened individuals. An integrated NBS public health program that is designed to continuously learn would fulfil these requirements, and a multi-dimensional framework for future NBS programs integrating medical, ethical, legal, and societal perspectives is overdue. (shrink)
- (1 other version)Moderate Epistemic Akrasia.Nicolás Lo Guercio -2018 -Crítica. Revista Hispanoamericana de Filosofía 50 (148):69-97.Moderate epistemic akrasia is the state a subject is in when she believes that p and suspends judgment about whether her evidence supports p. In this article it is argued that, given a certain understanding of the attitude of suspension of judgment, moderate epistemic akrasia is doxastically irrational. The paper starts with a brief introduction that makes explicit some background notions and clarifies the dialectics of the debate. Second, the well-known distinction between propositional and doxastic rationality is introduced and some (...) cases of improper basing are discussed. Third, two different cases are considered in which one might argue that moderate epistemic akrasia is doxastically rational, and it is argued that none is successful. Fourth, several objections are presented and answered. Finally, some conclusions are drawn. (shrink)No categories
- How does implicit and explicit knowledge fit in the consciousness of action?Nicolas Georgieff &Yves Rossetti -1999 -Behavioral and Brain Sciences 22 (5):765-766.Dienes & Perner's (D&P's) target articles proposes an analysis of explicit knowledge based on a progressive transformation of implicit into explicit products, applying this gradient to different aspects of knowledge that can be represented. The goal is to integrate a philosophical concept of knowledge with relevant psychophysical and neuropsychological data. D&P seem to fill an impressive portion of the gap between these two areas. We focus on two examples where a full synthesis of theoretical and empirical data seems difficult to (...) establish and would require further refinement of the model: action representation and the closely related consciousness of action, which is in turn related to self-consciousness. (shrink)
- Note: A Greek Scholium in the Corpus Gabirianum.Nicolás Bamballi -2023 -Arabic Sciences and Philosophy 33 (2):265-268.Kitāb muḫtaṣar waǧīz fī l-usṭuqussāt § 1, 1 p. 63, l. 6ff. Bos-Langermann: inna Arisṭūṭālīsa ḥadda l-usṭuqussa fī kitābihi l-mawsūmi bi-Kitābi s-samāʾi bi-an qāla: al-usṭuqussu huwa š-šayʾu llaḏī minhu {mā}3 yatakawwanu {mā huwa lahū usṭuqussun} 〈š-šayʾu〉 kawnan awwaliyyan wa-huwa mawǧūdun fī l-mukawwani immā bi-l-quwwati wa-immā bi-l-fiʿli. wa-ammā fī kitābihī fī-Mā baʿda ṭ-ṭabīʿiyyāti (!) fa-innahū ḫaṣṣa6 l-qawla bi-an qāla innahū mawǧūdun fī l-mukawwani bi-l-quwwati lā bi-l-fi ʿli. wa-ʿanā bi-qawlihi “llaḏī yakūnu minhu š-šayʾu kawnan awwaliyyan” absaṭa mā yakūnu l-mukawwanu lahū ay {awwal (...) kawn} aṣġara aǧzāʾi9 l-mukawwani. (shrink)
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David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Area Editors:
David Bourget
Gwen Bradford
Berit Brogaard
Margaret Cameron
David Chalmers
James Chase
Rafael De Clercq
Ezio Di Nucci
Esa Diaz-Leon
Barry Hallen
Hans Halvorson
Jonathan Ichikawa
Monte Johnson
Michelle Kosch
Øystein Linnebo
Paul Livingston
Brandon Look
Manolo Martínez
Matthew McGrath
Michiru Nagatsu
Susana Nuccetelli
Giuseppe Primiero
Jack Alan Reynolds
Darrell P. Rowbottom
Aleksandra Samonek
Constantine Sandis
Howard Sankey
Jonathan Schaffer
Thomas Senor
Daniel Star
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