Functional and Structural Brain Plasticity in Adult Onset Single-Sided Deafness.Yingying Shang,Leighton B. Hinkley,Chang Cai,Karuna Subramaniam,Yi-Shin Chang,Julia P. Owen,Coleman Garrett,DanielleMizuiri,Pratik Mukherjee,Srikantan S. Nagarajan &Steven W. Cheung -2018 -Frontiers in Human Neuroscience 12:410138.detailsSingle-sided deafness (SSD) or profound unilateral hearing loss obligates the only serviceable ear to capture all acoustic information. This loss of binaural function taxes cognitive resources for accurate listening performance, especially under adverse environments or challenging tasks. We hypothesized that adults with SSD would manifest both functional and structural brain plasticity compared to controls with normal binaural hearing. We evaluated functional alterations using magnetoencephalographic imaging (MEGI) of brain activation during performance of a moderately difficult auditory syllable sequence reproduction task and (...) assessed structural integrity using diffusion tensor magnetic resonance imaging (DTI). MEGI showed the SSD cohort to have increased induced oscillations in the theta band over the left superior temporal cortex and decreased induced gamma band oscillations over the frontal and parietal cortices between 175-475 ms following stimulus onset. DTI showed the SSD cohort to have extensive fractional anisotropy reduction in both auditory and non-auditory tracts and regions. Overlaying functional and structural changes revealed by the two imaging techniques demonstrated close registration of cortical areas and white matter tracts that expressed brain plasticity. Hence, complete loss of input from one ear in adulthood triggers both functional and structural alterations to dorsal temporal and frontal-parietal areas. (shrink)
Clinical Validation of the Champagne Algorithm for Epilepsy Spike Localization.Chang Cai,Jessie Chen,Anne M. Findlay,DanielleMizuiri,Kensuke Sekihara,Heidi E. Kirsch &Srikantan S. Nagarajan -2021 -Frontiers in Human Neuroscience 15.detailsMagnetoencephalography is increasingly used for presurgical planning in people with medically refractory focal epilepsy. Localization of interictal epileptiform activity, a surrogate for the seizure onset zone whose removal may prevent seizures, is challenging and depends on the use of multiple complementary techniques. Accurate and reliable localization of epileptiform activity from spontaneous MEG data has been an elusive goal. One approach toward this goal is to use a novel Bayesian inference algorithm—the Champagne algorithm with noise learning—which has shown tremendous success in (...) source reconstruction, especially for focal brain sources. In this study, we localized sources of manually identified MEG spikes using the Champagne algorithm in a cohort of 16 patients with medically refractory epilepsy collected in two consecutive series. To evaluate the reliability of this approach, we compared the performance to equivalent current dipole modeling, a conventional source localization technique that is commonly used in clinical practice. Results suggest that Champagne may be a robust, automated, alternative to manual parametric dipole fitting methods for localization of interictal MEG spikes, in addition to its previously described clinical and research applications. (shrink)
on the limited appeal of human engineering as a response to climate change.Danielle Zwarthoed -2014 -Bioethica Forum 7 (3):87-89.detailsIf bioethics should care about the environment, this could be, among other ways, by reflecting on certain radical solutions, such as biomedical human engineering. In a recent article, Liao, Sandberg and Roache consider reducing human size through biomedical treatments in order to mitigate climate change. In this viewpoint, we point out that the various methods used to reduce human height, be they sophisticated tech nologies or mere undernutrition, seem all subject to highly undesirable consequences. This is to show that one (...) of the problems with Liao et al.’s account is that it does not provide us with an ethical framework com prehensive enough to balance these consequences with the problematic effects of climate change. In sum, we wish to draw from the discussion of this specific example a more general claim. This claim is that, even if we accept that human engineering per se is not problematic, we nevertheless need a more comprehensive ethical theory than the mere claim that climate change should be mitigated in order to assess the desirability of human engineering. (shrink)
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Social Exchange in China: The Double-Edged Sword of Guanxi.Danielle E. Warren,Thomas W. Dunfee &Naihe Li -2004 -Journal of Business Ethics 55 (4):353-370.detailsWe present two studies that examine the effects of guanxi on multiple social groups from the perspective of Chinese business people. Study 1 (N = 203) tests the difference in perceived effects of six guanxi contextualizations. Study 2 (N = 195) examines the duality of guanxi as either helpful or harmful to social groups, depending on the contextualization. Findings suggest guanxi may result in positive as well as negative outcomes for focal actors and the aggregate.
Le phénomène de la vie de Jonas: L'absence insistante de Kant.Danielle Lories -2005 -Bulletin d'Analyse Phénoménologique 1.detailsKant est un interlocuteur fréquent et majeur de Hans Jonas. Il l?est assurément en philosophie pratique. Il lui est à la fois un repoussoir et un modèle à cet égard. Le Kant de la première Critique n?est pas non plus absent de l??uvre de Jonas, et il ne l?est pas, en particulier, du Phénomène de la vie , même s?il y est présent de manière assez sporadique. Mais un Kant dont l?absence est notable dans ce projet de biologie philosophique qui (...) entend rétablir, contre les sciences modernes, les droits du concept de finalité, c?est le Kant de la troisième Critique et singulièrement celui qui s?attelle à l?étude du jugement téléologique. Le titre de la Critique de faculté de juger n?est pas mentionné. Cette absence peut faire question et elle donne un angle d?attaque pour interroger le statut du projet jonassien dans le Phénomène de la vie . De manière abrupte : cette absence n?autorise-t-elle pas à penser que le projet est simplement précritique ? Quel autre sens pourrait-on donner à cette absence, et de quels indices dispose-t-on à cet égard ? Détecte-t-on, à seconde vue, une présence implicite de Kant ? On se contentera de poser ici quelques jalons dans l?instruction de ce dossier. Et l?on se gardera bien de prétendre à quelque démonstration que ce soit. Retournons donc à l?énoncé du projet de Jonas, et d?abord, inévitablement, à un très bref rappel des thèses kantiennes, pour baliser. (shrink)
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The (Re) Production of the Genetically Related Body in Law, Technology and Culture: Mitochondria Replacement Therapy.Danielle Griffiths -2016 -Health Care Analysis 24 (3):196-209.detailsAdvances in medicine in the latter half of the twentieth century have dramatically altered human bodies, expanding choices around what we do with them and how they connect to other bodies. Nowhere is this more so than in the area of reproductive technologies. Reproductive medicine and the laws surrounding it in the UK have reconfigured traditional boundaries surrounding parenthood and the family. Yet culture and regulation surrounding RTs have combined to try to ensure that while traditional boundaries may be pushed, (...) they are reconstructed in similar ways. This paper looks at the most recent RT to be permitted in the UK, mitochondria replacement therapy. Despite controversial media headlines surrounding the technique, MRT is in fact an example of how science and regulation seek to expand models of traditional relatedness in a way that doesn’t challenge the existing order. Yet, like other RTs, while attempts are made to ensure it doesn’t push traditional boundaries too far, fissures and inconsistencies appear in law and culture, which give interesting insights into how genetics, parentage and identity are being mediated in new but familiar ways. (shrink)
Realizing Reason: A Narrative of Truth and Knowing.Danielle Macbeth -2014 - Oxford, England: Oxford University Press.detailsDanielle Macbeth offers a new account of mathematical practice as a mode of inquiry into objective truth, and argues that understanding the nature of mathematical practice provides us with the resources to develop a radically new conception of ourselves and our capacity for knowledge of objective truth.
The hypothesized relationship between accountability and ethical behavior.Danielle Beu &M. Ronald Buckley -2001 -Journal of Business Ethics 34 (1):57 - 73.detailsUnethical behavior is important to study because it may have an adverse influence on organizational performance. This paper is an attempt to better understand why individuals behave as they do when faced with ethical dilemmas. We first explore the definition, theories and models of ethical behaviors and accountability. This discussion of societal ethics and accountability as forms of social control segues into a discussion of how accountability may influence ethical behaviors. Based on the business ethics and accountability literatures, we suggest (...) a number of research questions and hypotheses that need to be tested, as well as an appropriate research strategy. (shrink)
The effect of interaction topic and social ties on media choice and the role of four underlying mechanisms.Daniëlle N. M. Bleize,Emiel J. Krahmer,Alexander P. Schouten,Marjolijn L. Antheunis &Emmelyn A. J. Croes -2018 -Communications 43 (1):47-73.detailsThis study employed a scenario-based approach whereby participants were asked to choose which communication channel they prefer in certain situations. The first aim was to determine the effect of the topic of interactions and social ties on channel choice. The second aim was to examine the underlying mechanisms in the relation between interaction topic and social ties and channel choice. A questionnaire was administered among 238 participants, who were presented five communication scenarios with topics of low and high intimacy and (...) four social ties, ranging from weak to strong. Results revealed that preference for face-to-face communication was highest, followed by audio-only computer-mediated communication and text-based CMC. Preference for FtF communication was higher when people valued feeling co-present and decreased when people valued feeling anonymous. Our results showed that communication channel choice is strategic and the choice for FtF ommunication, audio-only and text-based CMC largely depends on controllability, anonymity and co-presence. (shrink)
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Autonomy-Based Reasons for Limitarianism.Danielle Zwarthoed -2018 -Ethical Theory and Moral Practice 21 (5):1181-1204.detailsThis paper aims to provide autonomy-based reasons in favour of limitarianism. Limitarianism affirms it is of primary moral importance that no one gets too much. The paper challenges the standard assumption that having more material resources always increases autonomy. It expounds five mechanisms through which having too much material wealth might undermine autonomy. If these hypotheses are true, a theory of justice guided by a concern for autonomy will support a limitarian distribution of wealth. Finally, the paper discusses two issues (...) autonomy-based limitarianism would raise. First, insofar as coercion invades autonomy, do autonomy-based reasons legitimate coercive measures to secure a limitarian distribution of wealth? Second, is a limitarian ethos consistent with the incentive to produce enough wealth to secure distributive justice? (shrink)
Education, Justice, and Democracy.Danielle Allen &Rob Reich (eds.) -2013 - University of Chicago Press.detailsRarely have these separate approaches been brought into the same conversation. Education, Justice, and Democracy does just that, offering an intensive discussion by highly respected scholars across empirical and philosophical disciplines.
Cheap Preferences and Intergenerational Justice.Danielle Zwarthoed -2015 -Revue de Philosophie Économique 16 (1):69-101.detailsThis paper focuses on a specific challenge for welfarist theories of intergenerational justice. Subjective welfarism permits and even requires that a generation, G1, inculcates cheap preferences in the next generation, G2. This would allow G1 to deplete resources instead of saving them, which seems to contradict the ideal of sustainability. The aim of the paper is to show that, even if subjective welfarism requires the cultivation of cheap preferences among future generations, it can accommodate two major objections to cheap preferences (...) engineering, the Autonomy Objection and the Fairness Objection. The paper argues that teaching autonomy-related abilities is compatible with cheap preferences engineering insofar as autonomy is understood as an end-state and not as a precondition. Furthermore, teaching autonomy-related abilities could even be required in order to improve G2’s prospects for well-being. However, since being autonomous renders G2 able to revise their initially cheap preferences, G1 should also save enough resources to enable members of G2 to do so. Therefore, cultivating cheap preferences among G2 does not allow G1 to deplete the available resources. (shrink)
The possibility of deliberate norm-adherence in AI.Danielle Swanepoel -2020 -Ethics and Information Technology 23 (2):157-163.detailsMoral agency status is often given to those individuals or entities which act intentionally within a society or environment. In the past, moral agency has primarily been focused on human beings and some higher-order animals. However, with the fast-paced advancements made in artificial intelligence, we are now quickly approaching the point where we need to ask an important question: should we grant moral agency status to AI? To answer this question, we need to determine the moral agency status of these (...) entities in society. In this paper I argue that to grant moral agency status to an entity, deliberate norm-adherence must be possible. In this paper I argue that, under the current status quo, AI systems are unable to meet this criterion. The novel contribution this paper makes to the field of machine ethics is first, to provide at least two criteria with which we can determine moral agency status. We do this by determining the possibility of deliberate norm-adherence through examining the possibility of deliberate norm-violation. Second, to show that establishing moral agency in AI suffer the same pitfalls as establishing moral agency in constitutive accounts of agency. (shrink)
When Ethical Tones at the Top Conflict: Adapting Priority Rules to Reconcile Conflicting Tones.Danielle E. Warren,Marietta Peytcheva &Joseph P. Gaspar -2015 -Business Ethics Quarterly 25 (4):559-582.detailsABSTRACT:While tone at the top is widely regarded as an important predictor of ethical behavior in organizations, we argue that recent research overlooks the various conflicting ethical tones present in many multi-organizational work settings. Further, we propose that the resolution processes promulgated in many firms and professional associations to reconcile this conflict reinforce the tone at the bottom or a tone at the top of the employee’s organization, and that both of these approaches can conflict with the tone at the (...) top of other important organizations such as professional and regulatory organizations. Here we adapt Integrative Social Contract Theory’s priority rules to propose a multi-tone reconciliation process which prioritizes conflicting ethical tones based upon features of the organization and the effects on society. Using three contextualizations, we demonstrate the effectiveness of the multi-tone reconciliation process over current processes. We conclude with recommendations for future research and implications for practice. (shrink)
Sexting and mandatory reporting: ethical issues in youth psychotherapy.Danielle Nelson,Tilman Schulte,Wendy Packman &E. L. Bunge -2021 -Ethics and Behavior 31 (3):205-214.detailsABSTRACT Engaging in sexting, such as sending or receiving of sexual words, pictures, or videos via technology, is a common behavior in minors and a rising trend. This study aimed to understand the ethical dilemmas that clinicians face when working with minors that engage in sexting under current mandated reporting standards. For this study, 178 graduate students and licensed clinicians who work with minors in the state of California completed an online survey involving vignettes concerning issues of sexting behaviors in (...) adolescents. Participants were asked to read each vignette and answer a series of questions regarding their knowledge and attitudes related to the presented issue and whether or not they would breach confidentiality in each case. Results indicated that participants, who had undergone specific training in issues of social media and technology, were significantly more likely to have more declarative knowledge of mandated reporting requirements, however, their reporting behavior was not significantly different from those, who had not previously had any training. Younger clinicians tended to report less than older clinicians. This study highlights the discrepancy that exists between the knowledge of mandated reporting standards relevant to sexting behaviors and clinicians’ reporting practice. (shrink)
Nursing art as a practical art: the necessary relationship between nursing art and nursing ethics.Danielle Blondeau -2002 -Nursing Philosophy 3 (3):252-259.detailsIn the last decade, nurse scholars have focused extensively on the nature of nursing and its relationship to art and science. This emphasis has also been accompanied by an increasing literature on nursing ethics. In spite of this growing interest, the relationship of nursing art and nursing ethics has been left unclear. This paper proposes that nursing must be considered as a practical art because this conception explicates the relationship of nursing art and nursing ethics. It is based on the (...) thesis that nursing art is subordinated to nursing ethics and as such is a moral art. Different conceptions of nursing art (craft and fine art) will be explored to show their limits. This will be followed by the conception of nursing art as a practical art. (shrink)
Two senses of medium independence.Danielle J. Williams -forthcoming -Mind and Language.detailsThe term “medium independence” has different meanings. One sense maps onto “abstract-as-abstracta” descriptions while the other maps onto “abstract-as-omission” descriptions. Both senses have been deployed when it comes to understanding the nature of physical computation. However, because medium independence is a polysemic term, the sense being used should be clearly stated. If the sense is not clearly stated, then those who wish to engage in debates regarding medium independence and physical computation run the risk of conflating different but related issues (...) which can have consequences when it comes to thinking about physical computation across contexts. (shrink)
Gaia Politics, Critique, and the "Planetary Imaginary".Danielle Sands -2020 -Substance 49 (3):104-121.detailsIn 2017, Bruce Clarke proposed that Gaia, the mythological goddess repurposed in the 1970s by James Lovelock and Lynn Margulis as geobiological trope, and later adapted for twenty-first century environmental discourse by Bruno Latour and Isabelle Stengers, is a vital resource in the cultivation of a “planetary imaginary” which attends to “our systemic entanglements”. Contemporary forms of Gaia discourse, Clarke argues, are “fit for communicative efficacy in the so-called Anthropocene epoch”. In an era marked by scalar and communicative disjunctions, Clarke’s (...) claim is significant. Whilst ultimately he deviates from Stengers and Latour, arguing that neither addresses “the cybernetics of Gaia” and... (shrink)
The Social Value of Knowledge and the Responsiveness Requirement for International Research.Danielle M. Wenner -2017 -Bioethics 31 (2):97-104.detailsEthicists have long recognized that two necessary features of ethical research are scientific validity and social value. Yet despite a significant literature surrounding the validity component of this dictate, until recently there has been little attention paid to unpacking what the social value component might require. This article introduces a framework for assessing the social value of research, and in particular, for determining whether a given research program is likely to have significant social value of the kind necessary to fulfill (...) the social value requirement. The article goes on to illustrate how this framework can provide a clearer account of the responsiveness requirement, an ethical dictum that is oft-repeated but whose content and value as a guideline in international research remains contested. Although I introduce this conception of social value in the context of the responsiveness requirement, the account offered can, and is intended to, stand alone as a tool for the assessment of the social value of research. As such it can be usefully applied to discussions about the value of comparative effectiveness trials, the assessment of the continued proliferation of me-too drugs and the research done to develop them, the demand for public access to study-generated data, and persistent deficits in the publication of negative results. (shrink)
Motivational Internalism and the Challenge of Amoralism.Danielle Bromwich -2016 -European Journal of Philosophy 24 (2):452-471.detailsMotivational internalism is the thesis that captures the commonplace thought that moral judgements are necessarily motivationally efficacious. But this thesis appears to be in tension with another aspect of our ordinary moral experience. Proponents of the contrast thesis, motivational externalism, cite everyday examples of amoralism to demonstrate that it is conceptually possible to be completely unmoved by what seem to be sincere first-person moral judgements. This paper argues that the challenge of amoralism gives us no reason to reject or modify (...) motivational internalism. Instead of attempting to diagnose the motivational failure of the amoral agent or restrict the internalist thesis in the face of these examples, I argue that we should critically examine the assumptions that underlie the challenge. Such an examination reveals that the examples smuggle in substantive assumptions that the internalist has no reason to accept. This argument has two important implications for the debate in moral motivation: first, it reveals that the motivational externalist needs a new argumentative strategy; and second, it shows that there is nothing especially problematic about a formulation of the thesis that captures the core internalist intuition that first-person moral judgements are necessarily accompanied by motivation. (shrink)
Clearing conceptual space for cognitivist motivational internalism.Danielle Bromwich -2010 -Philosophical Studies 148 (3):343 - 367.detailsCognitivist motivational internalism is the thesis that, if one believes that 'It is right to ϕ', then one will be motivated to ϕ. This thesis—which captures the practical nature of morality—is in tension with a Humean constraint on belief: belief cannot motivate action without the assistance of a conceptually independent desire. When defending cognitivist motivational internalism it is tempting to either argue that the Humean constraint only applies to non-moral beliefs or that moral beliefs only motivate ceteris paribus . But (...) succumbing to the first temptation places one under a burden to justify what is motivationally exceptional about moral beliefs and succumbing to the second temptation saddles one with a thesis that fails to do justice to the practicality intuition that cognitivist motivational internalism is suppose to capture. In this paper, I offer a way of defending cognitivist motivational internalism, which does not require accepting that there is anything motivationally unusual about moral beliefs. I argue that no belief satisfies the Humean constraint: all beliefs are capable of motivating without the assistance of a conceptually independent desire. (shrink)
Imprisonment in Classical Athens.Danielle Allen -1997 -Classical Quarterly 47 (1):121-135.detailsNineteenth–century scholars assumed that the Athenians as a community punished citizens with death, exile,atimia, and fines and used imprisonment only to hold those awaiting trial, those awaiting execution, and those unable to pay fines.1As they saw it, brief imprisonment in the stocks occasionally supplemented these penalties, but always as additional penalty–never as a penalty on its own. Barkan saw in the use of imprisonment as an additional penalty the likelihood of general penal imprisonment and used evidence from the oratorical corpus (...) to make an argument therefore.2 His argument seems to have been largely ignored–the nineteenth–century interpretation continuing dominant; and the issue, largely unexplored but for a few glancing references in recent scholarship.3 The issue remains, thus, sufficiently vexed to make worthwhile a restatement of the argument for the use of punitive imprisonment. Also, the evidence provides clues worth setting forth as to why and when punitive imprisonment developed. Indeed, these are sufficient to make an argument about the relevance of the development to Athenian political history. For the introduction of penal imprisonment in Athens proves an extremely important historical moment, marking as it does both the completion of a general will institutionalized (in a punishment of consumption of the wrong–doer within, rather than of expulsion from, the community) and a significant point in the establishment ofisonomia. (shrink)
Navigating Big Data dilemmas: Feminist holistic reflexivity in social media research.Danielle J. Corple,Jasmine R. Linabary &Cheryl Cooky -2018 -Big Data and Society 5 (2).detailsSocial media offers an attractive site for Big Data research. Access to big social media data, however, is controlled by companies that privilege corporate, governmental, and private research firms. Additionally, Institutional Review Boards’ regulative practices and slow adaptation to emerging ethical dilemmas in online contexts creates challenges for Big Data researchers. We examine these challenges in the context of a feminist qualitative Big Data analysis of the hashtag event #WhyIStayed. We argue power, context, and subjugated knowledges must each be central (...) considerations in conducting Big Data social media research. In doing so, this paper offers a feminist practice of holistic reflexivity in order to help social media researchers navigate and negotiate this terrain. (shrink)
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Axel Honneth: Critical Essays: With a Reply by Axel Honneth.Danielle Petherbridge (ed.) -2011 - Brill Academic.details_Axel Honneth: Critical Essays_ brings together critical interpretations of the work of Axel Honneth, from his earliest to his most recent writings, together with a comprehensive reply by Honneth that provides significant insights and clarifications into his project overall.
Who Was Plato?Danielle S. Allen -2012-12-10 - In Neville Morley,Why Plato Wrote. Blackwell. pp. 9–15.detailsThe prelims comprise: Half‐Title Page Wiley Series Page Title Page Copyright Page Dedication Page Table of Contents Acknowledgments Abbreviations.
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Reading Rorty:: A SKETCH OF A PLAN.Danielle Macbeth -2011 -Annales Philosophici 2:66-73.detailsThe following pages are focused on a better understanding of Richard Rorty‟s reflections on the problem of truth, emphasizing the idea that one of the keys to a better understanding of Rorty is to consider the fact that there are three very different kinds of discourse present in his philosophical endeavors. In order to support this unprecedented claim I bring forward the case of one of Plato‟s dialogues concerned with the definition of knowledge, Theaetetus. The similarities between Plato‟s dialogue and (...) Rorty are the core of my argumentation. (shrink)
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The ethics of managing people.Danielle Douglas -1996 -Business Ethics, the Environment and Responsibility 5 (3):139–142.details“Employees have rights by virtue of employment law and the contract of employment. They also have a third right, however: that of being treated with respect…” What this implies is explored here in detail by the Senior Partner of Phoenix Human Resources Consultants, 17 Den Road, Shortlands, Bromley, Kent BR2 ONH. Ms Douglas originally gave this presentation at a meeting of The Ethical Business Forum at London Business School.
Cosmetic Surgery: Regulatory Challenges in a Global Beauty Market.Danielle Griffiths &Alex Mullock -2018 -Health Care Analysis 26 (3):220-234.detailsThe market for cosmetic surgery tourism is growing with an increase in people travelling abroad for cosmetic surgery. While the reasons for seeking cosmetic surgery abroad may vary the most common reason is financial, but does cheaper surgery abroad carry greater risks? We explore the risks of poorly regulated cosmetic surgery to society generally before discussing how harm might be magnified in the context of cosmetic tourism, where the demand for cheaper surgery drives the market and makes surgery accessible for (...) increasing numbers of people. This contributes to the normalisation of surgical enhancement, creating unhealthy cultural pressure to undergo invasive and risky procedures in the name of beauty. In addressing the harms of poorly regulated surgery, a number of organisations purport to provide a register of safe and ethical plastic surgeons, yet this arguably achieves little and in the absence of improved regulation the risks are likely to grow as the global market expands to meet demand. While the evidence suggests that global regulation is needed, the paper concludes that since a global regulatory response is unlikely, more robust domestic regulation may be the best approach. While domestic regulation may increase the drive towards foreign providers it may also have a symbolic effect which will reduce this drive by making people more aware of the dangers of surgery, both to society and individual physical wellbeing. (shrink)
Beyond Empathy: Vulnerability, Relationality and Dementia.Danielle Petherbridge -2019 -International Journal of Philosophical Studies 27 (2):307-326.detailsABSTRACTThis paper brings together a phenomenological and vulnerability-theoretic approach to dementia. The paper challenges the view that subjects with dementia can simply be understood in terms of diminished cognitive capacities or that they have lost all vestiges of personhood or the capacity for meaningful interaction. Instead, drawing on vulnerability theory and the phenomenological work of Kristin Zeiler and Lisa Käll, an alternative view of persons with dementia is offered that is based on intersubjective and intercorporeal relations and accomplishments. A vulnerability (...) approach to dementia is developed that not only provides the basis for empathetic responses to illnesses such as dementia but also points to the intersubjective constitution of subjects more generally. The argument developed is that the notion of vulnerability designates a form of openness to others and that such openness is a precondition for empathy. (shrink)
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Embodied Social Habit and COVID-19: The Ethics of Social Distancing.Danielle Petherbridge -2022 -Puncta 5 (1):58-78.detailsThis paper employs a phenomenological approach to examine the centrality of embodied habit in both the proliferation and the transmission of COVID-19. The analysis focuses not only on the difficulty of amending embodied habits but on the question of the ethics of social distancing and the role of human agency in the amendment of such habits. To this effect, the relation between passivity and activity in the uptake of habit is emphasized and the active and agential aspects of embodied habit (...) are highlighted. In contrast to the predominance of more negative accounts of social distancing, the paper considers the kind of ethical reorientation that is required to amend embodied and social habit in the face of the mutual vulnerability evoked by COVID-19. This analysis is distinguished from more far-reaching government measures in relation to COVID-19; instead, it offers a consideration of the kinds of responsibility towards one another at the level of everyday life. (shrink)
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Barriers to Effective Deliberation in Clinical Research Oversight.Danielle M. Wenner -2016 -HEC Forum 28 (3):245-259.detailsEthical oversight of clinical research is one of the primary means of ensuring that human subjects are protected from the natural bias of researchers and research institutions in favor of experimentation. At a minimum, effective oversight should ensure that risks are minimized and reasonable in relation to anticipated benefits, protect vulnerable subjects from potential coercion or undue influence, ensure full and informed consent, and promote the equitable distribution of the risks and benefits of research. Because these assessments often involve value (...) judgments for which there are no agreed-upon objective standards, we rely on deliberative procedures thought to have the greatest likelihood of producing the right or best outcomes. Concerns about the potential for improperly functioning IRBs to waste scarce human and institutional resources and impede biomedical progress have motivated a surge in empirical research assessing their procedures and outcomes. Yet within this literature, there has been minimal attention paid to the social scientific evidence regarding how individuals and deliberating groups make decisions, nor how those data might inform IRB practice. This essay seeks to fill that gap, locating recent empirical data on IRB composition and process within the context of data regarding what I call “deliberative pathologies,” or instances when deliberation fails to live up to one or more aspect of the deliberative ideal because of systematic biases in the ways participants interact. The paper goes on to make evidence-based recommendations to reduce the vulnerability of IRB deliberations to the kinds of pathologies discussed and indicate directions for future research. (shrink)
Self, Personhood and Self-Awareness: A Phenomenological Analysis of Dementia.Danielle Petherbridge -2025 -Phenomenology and Mind 28:7.detailsThis paper takes a phenomenological approach to understanding self and personhood in dementia. The paper challenges the view that subjects with dementia can simply be understood in terms of diminished cognitive capacities or that they have lost all vestiges of self and personhood or the capacity for meaningful interaction. Instead, drawing on phenomenology, an alternative view is offered that can more adequately account for self and personhood, as well as self-awareness and self-experience in dementia. The view offered here is of (...) a body-orientated and relational view of personhood and selfhood. It not only assumes that cognition is always already embodied but significantly that embodiment and embodied memory are central to personhood. It also highlights the ways in which persons are constituted and affirmed through relation with others and considers the way in which surrounding worlds or care environments might be more or less enabling in contexts of dementia and aging by attending to personhood in care. (shrink)
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The Social Value of Knowledge and International Clinical Research.Danielle M. Wenner -2013 -Developing World Bioethics 15 (2):76-84.detailsIn light of the growth in the conduct of international clinical research in developing populations, this paper seeks to explore what is owed to developing world communities who host international clinical research. Although existing paradigms for assigning and assessing benefits to host communities offer valuable insight, I criticize their failure to distinguish between those benefits which can justify the conduct of research in a developing world setting and those which cannot. I argue that the justification for human subjects research is (...) fundamentally grounded in the social value of knowledge, and that this value is context-dependent in a manner which should inform our ethical evaluation of the conduct of research in specific settings. I propose a new framework for the assessment of research benefits assigned to developing world host communities, a natural implication of which is to limit the types of research projects which may permissibly be conducted in developing world settings. (shrink)