Factors influencing the decision-making of elderly acute leukemia patients in Japan regarding their treatment.Miki Fukuyama,Atsushi Asai,Taeko Hanada,KenjiSakai &Yasuhiro Kadooka -2017 -Eubios Journal of Asian and International Bioethics 27 (4):106-112.detailsObjective: This study examined the process through which elderly patients with new-onset acute leukemia make treatment decisions from the time of diagnosis, in order to identify factors influencing this decision-making process in Japan. Methods: Semi-structured interviews were conducted with twenty-two elderly patients with leukemia. The data were analyzed using the modified grounded theory approach. Results: The process of decision-making in elderly patients with leukemia includes three stages: Initial reactions at diagnosis, change in attitudes, and entrusting the physician with the treatment (...) plan. Initial reactions at diagnosis were affected by interactions with others that brought peace of mind to the patients. Change in attitudes was affected by encouragement from others to undergo treatment and their own motivation to face treatment. Patients came to entrust their treatment plan completely to their physician, because they wanted to feel relief and did not want to have to grapple with difficult medical information that was relevant to decision-making about their disease and treatment options. Conclusions: The process of decision-making in elderly patients with leukemia is affected by several factors and included three stages. Our present study findings can provide suggestions on how medical professionals might better support the process of decision-making in elderly patients with leukemia. (shrink)
Kenji Tsuda: Liberal Protestantism and Christian Studies at Kyoto University: A Case Study of Tetsutaro Ariga.Kenji Tsuda -2020 -Journal for the History of Modern Theology/Zeitschrift für Neuere Theologiegeschichte 27 (1):12-19.detailsAriga Tetsutaro (1899–1977) war Professor für das Studium des Christentums an der Universität Kyoto und gehörte dort der zweiten Professoren-generation an. Er legte die Grundlagen der Patristik und der Erforschung des Christentums in Japan. In seinem Hauptwerk “Origenes” hatte er den Historismus in der Theologie erforscht, aber nachdem er seinen Dienst als Professor an der staatlichen Universität aufgenommen hatte, die die Trennung von Staat und Religion hochhielt, suchte er nach Wegen, ein ‘Studium des Christlichen’ zu etablieren, das sich von der (...) Theologie unterschied. Dabei dienten ihm Schleiermachers “Kurze Darstellung des theologischen Studiums” und die Tradition des deutschen liberalen Protestantismus als Anhaltspunkte. Anstatt der Theologie, die den Glauben als methodischen Ausgangspunkt hat, und der Religionswissenschaft, die nur die distanzierte Objektivität als Ausgangspunkt wählt, schlug er als neuen Versuch ein Christliches Studium mit akademischem Standpunkt vor, bei dem der Gelehrte eine Forschungshaltung einnimmt, die durch ein Mindestmaß an vernünftiger Kritik und ‘Ur-Sympathie’ gegenüber der Religion geprägt ist. (shrink)
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The West as a Form of Anxiety: An Interview with NaokiSakai.Pedro Erber &NaokiSakai -2022 -Diacritics 50 (2):144-155.detailsAbstract:Pedro Erber discusses with NaokiSakai the history of Heidegger's influence on philosophy in Japan.
Chang’s Conjecture and weak square.HiroshiSakai -2013 -Archive for Mathematical Logic 52 (1-2):29-45.detailsWe investigate how weak square principles are denied by Chang’s Conjecture and its generalizations. Among other things we prove that Chang’s Conjecture does not imply the failure of \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\square_{\omega_1, 2}}$$\end{document}, i.e. Chang’s Conjecture is consistent with \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\square_{\omega_1, 2}}$$\end{document}.
The Fetus as a Research Subject.Kenji Matsui,Keiichiro Yamamoto &Tomohide Ibuki -2022 -American Journal of Bioethics 22 (3):76-78.detailsInterventions performed on a pregnant woman's body can affect the fetus in multiple ways. Such effects can be harmful to beneficial to the fetus. Unfortunately, the effects of new drugs and compoun...
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Žižek and Lacanian Henology—With a “Silent Partner”.Kenji Nobutomo -2018 -International Journal of Žižek Studies 12 (2).detailsThis article aims to clarify the meaning of henology for Lacan and Žižek. Žižek apparently rejects Neoplatonic way of thinking, but by considering Lacanian Henology through its origin, Etienne Gilson, Lacanian henology and Žižek’s Hegelian reading of the One become converged. Both of them think the movement of the One from one principle and its two aspects. The principle is that the One gives something that it does not have, and it corresponds to Lacanian definition of love. Regarding its two (...) aspects, the first one is the logical necessity that generates necessarily the One, and the second is the logical contingency that generates contingently the surplus element. By this, we can clarify the theoretical development of each period of Lacan. In early Lacan, henology was a logic that ties his “the Symbolic” and Freudian Death drive. In middle Lacan, his main concern was the mathematical logic as the logic of the Id, and henology became the generative logic of the subject of enunciation or the subject of the jouissance. But at the same time, this movement produces as a co-product a inassimilable remainder, “object a” with the subject of signifiant. In late Lacan, by virtue of the “necessary” movement of the One and its “contingent” co-product, the universe of the discourse became indeterminate, undecidable, “not-all,” which means for Lacan “the contingent.” This characteristic became the logic of Lacanian “sexuation.”. (shrink)
Tracking Child Language Development With Neural Network Language Models.Kenji Sagae -2021 -Frontiers in Psychology 12.detailsRecent work on the application of neural networks to language modeling has shown that models based on certain neural architectures can capture syntactic information from utterances and sentences even when not given an explicitly syntactic objective. We examine whether a fully data-driven model of language development that uses a recurrent neural network encoder for utterances can track how child language utterances change over the course of language development in a way that is comparable to what is achieved using established language (...) assessment metrics that use language-specific information carefully designed by experts. Given only transcripts of child language utterances from the CHILDES Database and no pre-specified information about language, our model captures not just the structural characteristics of child language utterances, but how these structures reflect language development over time. We establish an evaluation methodology with which we can examine how well our model tracks language development compared to three known approaches: Mean Length of Utterance, the Developmental Sentence Score, and the Index of Productive Syntax. We discuss the applicability of our model to data-driven assessment of child language development, including how a fully data-driven approach supports the possibility of increased research in multilingual and cross-lingual issues. (shrink)
Translation.NaokiSakai -2006 -Theory, Culture and Society 23 (2-3):71-78.detailsTranslation is an act of articulation that takes place in the social topos of difference or incommensurability. The topos of difference, to which translation is a response, is anterior to the conceptual difference of species or particularities. Yet, translation is often represented as a process of establishing equivalence according to the model of communication. This misapprehension of translation derives from the confusion of the act of translation with its representation. By representing translation that is unrepresentable in itself through the schema (...) of co-figuration, the representation of translation inscribes and re-inscribes the twin figures of languages between which a transfer of information is supposed to have taken place. This whole regime organized around the schema of co-figuration is a historical construct of modernity that has worked powerfully to project national/ethnic languages and the international world, only within which national languages are possible. Our task is to historicize this regime of translation. (shrink)
Implicational quantum logic.Kenji Tokuo -2022 -Axiomathes 32 (2):473-483.detailsA non-classical subsystem of orthomodular quantum logic is proposed. This system employs two basic operations: the Sasaki hook as implication and the _and-then_ operation as conjunction. These operations successfully satisfy modus ponens and the deduction theorem. In other words, they form an adjunction in terms of category theory. Two types of semantics are presented for this logic: one algebraic and one physical. The algebraic semantics deals with orthomodular lattices, as in traditional quantum logic. The physical semantics is given as a (...) procedure for deriving a final segment of a series of yes-no experiments. (shrink)
Resolutions Against Uniqueness.Kenji Lota &Ulf Hlobil -2021 -Erkenntnis 88 (3):1013–1033.detailsThe paper presents a new argument for epistemic permissivism. The version of permissivism that we defend is a moderate version that applies only to explicit doxastic attitudes. Drawing on Yalcin’s framework for modeling such attitudes, we argue that two fully rational subjects who share all their evidence, prior beliefs, and epistemic standards may still differ in the explicit doxastic attitudes that they adopt. This can happen because two such subjects may be sensitive to different questions. Thus, differing intellectual interests can (...) yield failures of uniqueness. This is not a merely pragmatic phenomenon. (shrink)
On Katětov and Katětov–Blass orders on analytic P-ideals and Borel ideals.HiroshiSakai -2018 -Archive for Mathematical Logic 57 (3-4):317-327.detailsMinami–Sakai :883–898, 2016) investigated the cofinal types of the Katětov and the Katětov–Blass orders on the family of all \ ideals. In this paper we discuss these orders on analytic P-ideals and Borel ideals. We prove the following:The family of all analytic P-ideals has the largest element with respect to the Katětov and the Katětov–Blass orders.The family of all Borel ideals is countably upward directed with respect to the Katětov and the Katětov–Blass orders. In the course of the proof (...) of the latter result, we also prove that for any analytic ideal \ there is a Borel ideal \ with \. (shrink)
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Decidability of quantum modal logic.Kenji Tokuo -forthcoming -Logic Journal of the IGPL.detailsThe decidability of a logical system refers to the existence of an algorithm that can determine whether any given formula in that system is a theorem. In this paper, Harrop’s lemma is used to prove the decidability of quantum modal logic.
BDNF variant linked to anxiety-related behaviors.Kenji Hashimoto -2007 -Bioessays 29 (2):116-119.detailsBrain‐derived neurotrophic factor (BDNF) is the most‐abundant neurotrophin in the brain. In mammals, it is synthesized as a precursor called proBDNF, which is proteolytically cleaved to generate mature BDNF. The BDNF gene is located on chromosome 11p13, and a functional single nucleotide polymorphism (SNP) of this gene has been shown to produce a valine (Val)‐to‐methionine (Met) substitution in the proBDNF protein at codon 66 (Val66Met). Several papers suggest that this SNP is related to decreased hippocampal volume and hippocampus‐mediated memory performance (...) in humans. Recently, Chen et al.1 generated a variant BDNF mouse (BDNFMet/Met) that reproduces the phenotypic hallmarks in humans with a variant Met allele. In the behavioral analysis, BDNFMet/Met mice show increased anxiety‐related behaviors. This mini‐review examines the impact of Met substitution of proBDNF on anxiety‐related behaviors. BioEssays 29: 116–119, 2007. © 2007 Wiley Periodicals, Inc. (shrink)
The Political Discourse of International Order in Modern Japan: 1868–1945.Sakai Tetsuya -2008 -Japanese Journal of Political Science 9 (2):233-249.detailsThis article discusses what constituted Japan's conception of the world order, by analyzing political discourse of international order in modern Japan. It has been generally assumed that the Japanese vision of international order in the pre-World War II years was dominated by a belief in the supremacy of the sovereign state. Contrary to the conventional supposition, this paper will argue that modern Japan actually abounded in discourses of transnationalism, and that most of them cannot be seen as the product of (...) liberal ideas but rather the result of an unstable image of the sovereign state system. Surveying the historical development of political discourse of sovereignty and colonial administration in modern Japan, the way in which the ambivalence of Japanese transnationalism had affected the theoretical construction of the international order will be elucidated. Keeping in mind that previous studies on the genealogy of international relations have focused exclusively on the paradigmatic debate over the League of Nations, this article will also pay more attentions to the fact that rearrangement of empire had occupied the significant place in building the image of the world order. Based on the historical considerations mentioned above, the conclusion will offer generalized consideration of what constituted Japan's conception of the world order. (shrink)
Tanabe Hajime to Hiromatsu Wataru: kondakushita shisa to kihatsusuru tsūkaku no naka de.Kenji Yonemura -2015 - Tōkyō-to Bunkyō-ku: Ochanomizu Shobō.details田辺は自己の生を包摂する時代の趨勢と真摯に対峙し、廣松は「近代」の陥穽を注視し絶えず他者との協働を考察し続けた。この二人の視座から「啓蒙の弁証法」の陥穽に落ちた日本社会と日本人の「生の姿」を考えていく 。.
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On Dharmakīrti’s Notion of Contingency/Dependence, with a Special Focus on vināśa.MasamichiSakai -2018 -Journal of Indian Philosophy 46 (3):419-436.detailsThe concept of contingency is very much debated. In this paper, I’ll offer a novel interpretation of it in Dharmakīrti’s ontology, focusing on his treatment and understanding of vināśa which is, according to Dharmakīrti, not contingent and thus occurs necessarily to everything. I will do so by clarifying some important terms, motivating and explaining Dharmakīrti’s position, and analyzing firsthand some Dharmakīrtian debate excerpts with Nyāya and/or Vaiśeṣika philosophers as the main opponents. In the course of this, I will show that (...) basically, for Dharmakīrti, contingency is tantamount to dependency, whereas Nyāya and/or Vaiśeṣika authors, e.g., Śrīdhara and Bhāsarvajña, claim that something can be dependent on something else and still be necessary. (shrink)
Review Mechanisms for Advanced Medical Therapies in Japan and Thailand: A Proposal for the Use of Expert Clinical Benefit Assessments at Designated Institutions.Kenji Matsui,Nipan Israsena,Jaranit Kaewkungwal,Pornpimon Adams,David Wendler &Reidar K. Lie -2025 -Asian Bioethics Review 17 (1):101-115.detailsAdvanced new therapies, such as stem cell and gene therapies and xenotransplantation, represent challenges for regulatory and ethical review. Major drug agencies, such as in the U.S., India, and Europe, have asserted regulatory authority and require ethics review by local ethics review committees, using the same strict requirements as those for standard drug approvals. In spite of this, unapproved and undocumented stem cell clinics flourish in all of these places, suggesting that current approaches do not offer patients sufficient protection. Japan (...) has attempted another approach, requiring approvals at local levels for all regenerative medical procedures, and a faster approval of promising new interventions. The Japanese approach has, however, also been criticized as not striking a proper balance between early access and a proper assessment of safety and effectiveness. For smaller and less-resourced countries, such as Thailand, one major challenge is limited expertise to conduct the evaluation of these advanced new therapies. This article provides an overview of the issues facing regulators and proposes that countries should restrict the early adoption of advanced new therapies to specialized clinics with appropriate scientific and ethical expertise for review. Review in these institutions should focus on expert clinical benefit assessments for individual patients being offered such interventions, independently of whether they are offered as research or therapy. (shrink)
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Privacy shakes Japan’s statistics on health & welfare.Kenji Matsui &Reidar Lie -2007 -Eubios Journal of Asian and International Bioethics 17 (2):41-48.detailsIn 2005 Japan completed its first census after the Personal Information Protection Law went into force in April 2005. The debate about the new law raised privacy concerns for the first time among the public. The news-media also provided several examples of possible lack of safeguards in the data collection of sensitive personal information required for the census. The result was the highest non-response rate ever for the Japanese census. Consequently, its accuracy and role as a source for the reliable (...) national statistics for health/welfare policy-making is now critically threatened. In this paper we argue the necessity to adopt specific safeguards to protect personal data in any future census if the trend of increasing non-response rates is to be reversed. We provide some suggestions for such safeguards, and criticize the Japanese government’s response of focusing exclusively on the mechanism of data collection as a means of meeting the privacy challenge. (shrink)
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