Biobanking for human microbiome research: promise, risks, and ethics.Yonghui Ma,Hua Chen,Ruipeng Lei &Jianlin Ren -2017 -Asian Bioethics Review 9 (4):311-324.detailsWith the advancement of human microbiome research, it is inevitable that a growing number of biobanks will include a collection of microbiota specimens to characterize the microbial communities that inhabit the human body and explore the relationships between the microbiota and their human hosts. Biobanks of human microbiota and their associated genetic information may become a valuable health resource. But, this area of research also presents ethical and social problems, some of which are distinct from those faced by biobanks that (...) store human tissue samples. This paper examines four core issues which are considered highly relevant to microbiome biobanking: the nature of human microbiome samples and how different understandings have an impact on benefit/risk evaluation, privacy, informed consent, and returning the result to participants. We argue that these issues should be addressed early on in microbiome research projects and also call for adjusting or developing new governance mechanism to better accommodate these changes. (shrink)
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CEO Hubris and Firm Pollution: State and Market Contingencies in a Transitional Economy.Lu Zhang,Shenggang Ren,Xiaohong Chen,Dayuan Li &Duanjinyu Yin -2018 -Journal of Business Ethics 161 (2):459-478.detailsThis study focuses on CEO hubris and its effect on corporate unethical behaviour—pollution in particular, and in addition examines critical institutional contingencies [state ownership, political connection and industrial competition] which may moderate this effect. With data from over-polluting listed firms based on the real-time pollution monitoring system in transitional China from 2015 to 2017, we find that CEO hubris is significantly positively related to firm pollution, and that the moderating role of SO is not significant, that PC positively moderates the (...) hubris–pollution relationship and that industrial competition negatively moderates this relationship. These findings contribute to research on the upper echelon theory, institutional theory and the growing literature on emerging economies. (shrink)
Rethinking other minds: Wittgenstein and Levinas on expression.Søren Overgaard -2005 -Inquiry: An Interdisciplinary Journal of Philosophy 48 (3):249 – 274.detailsOne reason why the problem of other minds keeps cropping up in modern philosophy is that we seem to have conflicting intuitions about our access to the mental lives of others. On the one hand, we are inclined to think that it is wrong to claim, like Cartesian dualists must, that the minds of others are essentially inaccessible to direct experience. But on the other hand we feel that it is equally wrong to claim, like the behaviorists, that the mental (...) lives of others are completely accessible to an outside spectator. This paper attempts to address the problem of the accessibility of other minds while staying faithful to both these intuitions. Central to this undertaking is the idea that we express our mental lives in our bodily behavior. With a firm grasp of the notion of expression, as it is developed in the writings of Wittgenstein and Levinas, we can understand how other minds can be directly perceivable and yet retain a certain inaccessibility. The key is to emphasize the difference between the expressive appearance of a human being and the way an object appears in perception. (shrink)
Should we presume moral turpitude in our children? – Small children and consent to medical research.John Harris &Søren Holm -2003 -Theoretical Medicine and Bioethics 24 (2):121-129.detailsWhen children are too young to make their ownautonomous decisions, decisions have to be madefor them. In certain contexts we allow parentsand others to make these decisions, and do notinterfere unless the decision clearly violatesthe best interest of the child. In othercontexts we put a priori limits on whatkind of decisions parents can make, and/or whatkinds of considerations they have to take intoaccount. Consent to medical research currentlyfalls into the second group mentioned here. Wewant to consider and ultimately reject one (...) ofthe arguments put forward for putting medicalresearch into the second category. We willargue that some objections to children'sparticipation in research are either based onan implausibly restrictive conception of whatis in fact in the child's best interests orthat there is an implicit and false premisehidden in this argument; i.e., the premise thatour children have so deeply fallen into moralturpitude that we must assume that they wouldnot want to fulfill their moral obligations,or, that they will grow up to be morallydeficient and will then wish not to have actedwell while a child. (shrink)
Founder CEOs, personal incentives, and corporate social irresponsibility.Xi Zhong,Liuyang Ren &Ge Ren -2021 -Business Ethics, the Environment and Responsibility 31 (1):17-32.detailsBusiness Ethics, the Environment & Responsibility, EarlyView.
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The privacy of tutankhamen – utilising the genetic information in stored tissue Samples.Søren Holm -2001 -Theoretical Medicine and Bioethics 22 (5):437-449.detailsRecent technical developments in genetictesting has led to a situation where the DNA inpreviously stored tissue samples can beextracted and used for genetic analysis. Thisraises the question of how to decide whether aspecific use of such samples should be allowed.Using the genetic testing of ancient DNA ingeneral, and the DNA of the pharaoh Tutankhamenin particular as examples this paper analysesthe question. It investigates whether ethicalframeworks based on proxy consent, culturalaffiliation, ownership, or the privacy rightsof the dead are appropriate and justifiable (...) inthis context. The conclusion is that frameworksbased on proxy consent, cultural affiliation,and ownership are not very useful. (shrink)
Research on the Relationship between Business Cycle and Industrial Fluctuations in Northeast China Based on Complete Ensemble Empirical Mode Decomposition with Adaptive Noise.Yinan Zhou,Guofeng Gu &Qiushuang Ren -2021 -Complexity 2021:1-16.detailsThe Chinese economy has developed rapidly since the reform and opening up, but economic growth in Northeast China has declined dramatically after the 21st century. In this context, exploring the characteristics of economic and industrial fluctuations in the northeast of China and their relationship is beneficial to alleviating economic fluctuations and promoting stable economic development from the perspective of industrial development. The relationship between economic and industrial fluctuations in the three provinces of Northeast China was reexamined from the angle of (...) fluctuation components with the complete ensemble empirical mode decomposition with adaptive noise algorithm. The results obtained are as follows: In the three northeastern provinces of China, economic fluctuations were almost free from the influence of the primary industry, most affected by the secondary industry, and gradually influenced by the tertiary industry after the 21st century. Regarding the short-term business cycle of each province, economic development was the most stable when the market and government participated in the development of the secondary industry simultaneously. The midterm business cycle of Jilin Province was affected by the investment of equipment in secondary and tertiary industries, while that of Liaoning Province was affected by the investment of equipment in the secondary industry. Investment in the equipment of the secondary industry and the construction of secondary and tertiary industries was the key to maintaining the stability of long-term business cycle in Heilongjiang Province, and that in the construction of secondary and tertiary industries was the key to maintaining the stability of long-term business cycles in Jilin and Liaoning Provinces. (shrink)
From Passive to Active: The Positive Spillover of Required Employee Green Behavior on Green Advocacy.Shujie Zhang,Shuang Ren &Guiyao Tang -2024 -Journal of Business Ethics 192 (1):57-76.detailsThis research investigates whether required employee green behavior can spill over to a proactive form of green behavior termed green advocacy. Drawing on self-perception theory, we theorize and test a moderated mediation model in which required employee green behavior is positively associated with green advocacy via the mediation of pro-environmental self-identity, with the strength of such association contingent upon employee moral identity. Data collected in three waves from 297 employees at a large manufacturing firm in China provide support for the (...) research model. Results show that pro-environmental self-identity explains the positive association between required employee green behavior and green advocacy and that its mediating role is stronger when moral identity is higher (vs. lower). This study advances workplace green behavior research by identifying a novel psychological path and extending knowledge about a boundary condition. (shrink)
Reaction qualifications in the eyes of the people: An experimental‐philosophical study based on US survey data.Viki Møller Lyngby Pedersen,Didde Boisen Andersen,Søren Flinch Midtgaard &Kim Mannemar Sønderskov -2024 -Theoria 90 (6):624-642.detailsIs it fair for employers to select candidates partly based on how the employers think customers react to the candidates' appearances, that is, based on candidates' reaction qualifications? Both philosophically (in the literature on wrongful discrimination) and empirically, this question has recently been getting attention. Here, we focus on a theory of unfair disadvantages emphasizing (i) whether the possession of the appearance feature in question reflects choices on the part of the candidate and (ii) whether the appearance feature in question (...) reflects values or convictions of importance to the candidate. We scrutinize the theory by evaluating how well these factors map on to folk intuitions about wrongful discrimination using an experimental-philosophical approach and data from the United States. We do so on the presumption that coherence with folk intuitions is one desideratum for a philosophical theory and that attention should be given to potential discrepancies between philosophical theories and folk intuitions. Our central finding is that there is only general support for factor (i), not (ii), in the American population. Our study also adds to the extant empirical literature on reaction qualifications that tend to focus on the employer's side of the matter, not the candidate's as we do. (shrink)
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Short Forms of the Cross-Cultural (Chinese) Personality Assessment Inventory: Reliability, Validity, and Measurement Invariance Across Gender.Mingjie Zhou,Duan Huang,Fen Ren,Weiqiao Fan,Weiqi Mu,Fugui Li,Jianxin Zhang &Fanny M. Cheung -2021 -Frontiers in Psychology 12.detailsFilling out long questionnaires can be frustrating, unpleasant, and discouraging for respondents to continue. This is why shorter forms of long instruments are preferred, especially when they have comparable reliability and validity. In present study, two short forms of the Cross-cultural Personality Assessment Inventory were developed and validated. The items of the short forms were all selected from the 28 personality scales of the CPAI-2 based on the norm sample. Based on some priori criteria, we obtained the appropriate items and (...) constructed the 56-item Chinese Personality Assessment Inventory and the 28-item CPAI. Then, we examined the factor structure of both short forms with Exploratory SEM and replicated the four-factor structure of the original CPAI-2, reflecting the four personality domains of Chinese people, namely, Social Potency, Dependability, Accommodation, and Interpersonal Relatedness. Further analyses with ESEM models demonstrate full measurement invariance across gender for both short forms. The results show that females score lower than males on Social Potency. In addition, these four factors of both short forms have adequate internal consistency, and the correlation patterns of the four factors, the big five personality traits, and several health-related variables are extremely similar across the two short forms, reflecting adequate and comparable criterion validity, convergent validity, and discriminant validity. Overall, the short versions of CPAI-2 are psychometrically acceptable and have practically implications for measuring Chinese personality and cross-cultural research. (shrink)
A Look Into the Power of fNIRS Signals by Using the Welch Power Spectral Estimate for Deception Detection.Jiang Zhang,Jingyue Zhang,Houhua Ren,Qihong Liu,Zhengcong Du,Lan Wu,Liyang Sai,Zhen Yuan,Site Mo &Xiaohong Lin -2021 -Frontiers in Human Neuroscience 14.detailsNeuroimaging technologies have improved our understanding of deception and also exhibit their potential in revealing the origins of its neural mechanism. In this study, a quantitative power analysis method that uses the Welch power spectrum estimation of functional near-infrared spectroscopy signals was proposed to examine the brain activation difference between the spontaneous deceptive behavior and controlled behavior. The power value produced by the model was applied to quantify the activity energy of brain regions, which can serve as a neuromarker for (...) deception detection. Interestingly, the power analysis results generated from the Welch spectrum estimation method demonstrated that the spontaneous deceptive behavior elicited significantly higher power than that from the controlled behavior in the prefrontal cortex. Meanwhile, the power findings also showed significant difference between the spontaneous deceptive behavior and controlled behavior, indicating that the reward system was only involved in the deception. The proposed power analysis method for processing fNIRS data provides us an additional insight to understand the cognitive mechanism of deception. (shrink)
Stay Out of the Sunbed! Paternalistic Reasons for Restricting the Use of Sunbeds.Didde Boisen Andersen &Søren Flinch Midtgaard -2017 -Public Health Ethics 10 (3).detailsThe use of tanning beds has been identified as being among the most significant causes of melanoma and non-melanoma skin cancer. Accordingly, the activity is properly seen as one that involves profound harm to self. The article examines paternalistic reasons for restricting sunbed usage. We argue that both so-called soft and hard paternalistic arguments support prohibiting the use of sunbeds. We make the following three arguments: an argument from oppressive patterns of socialization suggesting that the autonomous nature of the conduct (...) in question is questionable; an argument from so-called evaluative delusions in which individuals attach incorrect weights to some of their values; a strictly hard paternalistic argument appealing to the harm in itself pertaining to the use of sunbeds. (shrink)
Perspective of Dimensional Analysis in Medical Science.Wojciech Kowalewski,Magdalena Roszak,Barbara Kołodziejczak &Anna Ren-Kurc -2017 -Studies in Logic, Grammar and Rhetoric 51 (1):19-37.detailsThis paper presents several applications of the dimensional analysis method to problems investigated in medical sciences. The method is used to analyze various complex processes without using formal laws governing the same. It is particularly suitable for a general analysis of fluid transfer in the human body. This paper mainly serves as an overview of selected applications, mostly those emerging in the recent years, and includes a discussion of the mathematical fundamentals of dimensional analysis together followed by its critical analysis. (...) Containing detailed calculations of two examples, the paper also serves as training material in the area of the computational method of the dimensional analysis algorithm. (shrink)
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The Law and Religious Market Theory: China, Taiwan and Hong Kong.Jianlin Chen -2017 - Cambridge University Press.detailsWith comparative case studies from China, Taiwan and Hong Kong,Jianlin Chen's new work offers a fresh, descriptive and normative perspective on law and religion. This presentation of the original law and religious market theory employs an interdisciplinary approach that sheds light on this subject for scholars in legal and sociological disciplines. It sets out the precise nature of religious competition envisaged by the current legal regimes in the three jurisdictions and analyses how certain restrictions on religious practices may (...) facilitate normatively desirable market dynamics. This updated and invaluable resource provides a new and insightful investigation into this fascinating area of law and religion in Greater China today. (shrink)
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Researching Leadership Behavior- in Search of a Middle Ground Between Objective and Subjective Approaches.Peter Sørensen,Søren Harnow Klausen &Bruno Broucker -2023 -Philosophy of Management 22 (2):173-186.detailsThe question of how to become and remain an effective leader has been discussed for decades, and the answers that have been proposed have led to numerous theories and taxonomies of leadership behavior. By taking a critical approach to a contemporary integrative model of leadership behavior, this theoretical research proposes an alternative approach that can supplement both the integrative model and current leader–member exchange theory. Our approach is sensitive to both objective and subjective aspects of leadership behavior. We argue that (...) perceptions of leadership behavior are influenced by interpersonal relations and contextual variables in an organization. We further argue that multilevel aspects must be investigated to understand leadership behavior and that the perceptions thereof shape and are shaped by relations and contextual variables. A distinct methodological approach based on mixed methods is then proposed to better understand what influences perceptions of leadership behavior. The article discusses the conceptual, epistemological, and methodological consequences of studying leadership behavior and perceptions of such behavior. (shrink)
The Membrane Potential Has a Primary Key Equation.Titus Mulembo,Bernard Delalande,Ren Sugimori,Toi Nakahata &Hirohisa Tamagawa -2023 -Acta Biotheoretica 71 (3).detailsIt is common to say that the origin of the membrane potential is attributed to transmembrane ion transport, but it is theoretically possible to explain its generation by the mechanism of ion adsorption. It has been previously suggested that the ion adsorption mechanism even leads to potential formulae identical to the famous Nernst equation or the Goldman-Hodgkin-Katz equation. Our further analysis, presented in this paper, indicates that the potential formula based on the ion adsorption mechanism leads to an equation that (...) is a function of the surface charge density of the material and the surface potential of the material. Furthermore, we have confirmed that the equation holds in all the different experimental systems that we have studied. This equation appears to be a key equation that governs the characteristics of the membrane potential in all systems. (shrink)
Work-Family Conflict, Happiness and Organizational Citizenship Behavior Among Professional Women: A Moderated Mediation Model.Ying Pan,Nadilai Aisihaer,Qinyi Li,Yue Jiao &Shengpei Ren -2022 -Frontiers in Psychology 13.detailsThis study investigates the association between work-family conflict and organizational citizenship behavior and examines the mediated role of subjective happiness between and the moderated part of family support. A moderated mediation model is established based on the Conservation of Resources theory. We collected data from 386 employees of nine companies in China. This study shows that the work-family conflict of female professional employees is negatively correlated with organizational citizenship behavior, and that the relationship is mediated by subjective well-being. Furthermore, female (...) professional employees’ family support moderates the effects of work-family conflict on subjective happiness and organizational citizenship behavior, with the relationship weaker when family support is higher. This study enriches the literature on work-family conflict by using family support as a mediating mechanism for work-family conflict. It enhanced our understanding of the influencing mechanisms of organizational citizenship behavior by constructing a more detailed model. (shrink)
Benevolent Creativity Buffers Anxiety Aroused by Mortality Salience: Terror Management in COVID-19 Pandemic.Yu-Xin Cui,Xiang Zhou,Chong Zu,Hong-Kun Zhai,Bo-Ren Bai,Yu-Mei Xu &Duo Li -2020 -Frontiers in Psychology 11.detailsWith the outbreak of the COVID-19 crisis, the public keeps getting epidemic-related information on the media. News reports on the increasing number of fatalities have exposed individuals to death, which causes negative emotional experiences such as tension, anxiety, and fear. This study aimed to investigate whether creativity could serve as an anxiety-buffer when mortality is salient. Based on previous findings, the present study utilized type of creative task and personal search for meaning as moderators. In Study 1, a 2 × (...) 2 between-subject design was utilized, and 168 subjects were randomly assigned to four experimental conditions. In Study 2, 221 subjects were recruited. The experimental procedure was similar to Study 1, except that the priming paradigm of mortality was changed and search for meaning was included as an additional moderating variable. State anxiety was measured as the dependent variable in both studies. Results of Study 1 showed that, while the benevolent creative task could buffer anxiety in the mortality salience condition, the malevolent creative task did not have the same effect. Furthermore, there was a significant interaction between mortality salience, type of creative task, and search for meaning in life on anxiety. In Study 2, the buffering function of benevolent creativity was more intense for participants with a higher level of search for meaning. Together, these findings reveal the influence of different types of creative tasks on individual anxiety levels under death priming conditions and the moderating effect of search for meaning in this relationship. Further, they suggest the need to focus on the role of creativity in terror management. (shrink)
Resource allocation in the Covid-19 health crisis: are Covid-19 preventive measures consistent with the Rule of Rescue?Julian W. März,Søren Holm &Michael Schlander -2021 -Medicine, Health Care and Philosophy 24 (4):487-492.detailsThe Covid-19 pandemic has led to a health crisis of a scale unprecedented in post-war Europe. In response, a large amount of healthcare resources have been redirected to Covid-19 preventive measures, for instance population-wide vaccination campaigns, large-scale SARS-CoV-2 testing, and the large-scale distribution of protective equipment to high-risk groups and hospitals and nursing homes. Despite the importance of these measures in epidemiological and economic terms, health economists and medical ethicists have been relatively silent about the ethical rationales underlying the large-scale (...) allocation of healthcare resources to these measures. The present paper seeks to encourage this debate by demonstrating how the resource allocation to Covid-19 preventive measures can be understood through the paradigm of the Rule of Rescue, without claiming that the Rule of Rescue is the sole rationale of resource allocation in the Covid-19 pandemic. (shrink)
The Effect of the Non-task Language When Trilingual People Use Two Languages in a Language Switching Experiment.Jianlin Chen &Hong Liu -2020 -Frontiers in Psychology 11.detailsThis study investigated the effect of non-task language in language switching experiment. Non-task language refers to participants’ language(s) (regardless of proficiency level) that are not used in any trials throughout the experiment. We recruited 60 Tibetan-Chinese-English trilinguals (grade-12 high school students with a median age of 17) to perform a lexical decision (word vs. non-word) task in only two of their languages. We repeated the experiment three times to present each language pair once. In each experiment, the participants were divided (...) into two groups which significantly contrasted with each other in their non-task language while remained comparable in the two task languages. Response time (RT) and error rate (ER) have been examined to evaluate task performance. The interaction between task performance and the participants’ proficiency in the non-task language was also examined. The results showed null effect of language switching. In addition, the effect of the non-task language was not found. These results were interpreted with reference to the main models of bilingual visual word recognition and the role of orthography specificity. (shrink)
Fractional-Order Modeling and Analysis of a Variable Structure Hybrid Energy Storage System for EVs.Jianlin Wang,Dan Xu,Jiahui Zhou &Jinlu Mao -2020 -Complexity 2020:1-10.detailsHybrid energy storage system has been widely studied as an important technology for electric vehicles. Since the hybrid energy storage system is a nonlinear and complex system, the modeling of the system and the high-precision nonlinear control strategy are technical difficulties for research. The establishment of a high-precision mathematical model of the hybrid energy storage system is the basis for the study of high-quality nonlinear control algorithms. Fortunately, the theory of fractional calculus can help build accurate mathematical models of hybrid (...) energy storage systems. In order to obtain the high-quality nonlinear control strategy of this complex system, this paper, respectively, carried out fractional-order modeling and analysis on the three basic equivalent working states of the hybrid energy storage system of electric vehicles. Among them, the fractional-order average state space model is carried out for the equivalent Buck and Boost mode. Also, the steady-state analysis of the equivalent Dual-Boost mode is carried out by combining the fractional-order calculus theory with the equivalent small parameter variable method. Finally, the effectiveness and precision of the fractional-order model are proved by simulation and experiment. (shrink)
Modeling the Impact of Virtual Contact Network with Community Structure on the Epidemic Spreading.Jianlin Zhou &Haiyan Liu -2022 -Complexity 2022:1-13.detailsThe epidemic spreading is closely related to the spread of information, and it will coevolve with the information transmission. Considering that the network structure has a significant impact on network dynamics and the virtual contact networks have obvious community structures in reality, in this article, we built a multiplex network, which contains a community structure to explore the interplay of the coupled spread dynamics. We first use a microscopic Markov chain approach to characterize the coupled disease-awareness dynamics and then analyze (...) the effect of different factors on the coevolution of information dissemination and epidemic spreading based on the Monte Carlo simulation. The simulation results show that promoting the dissemination of information is indeed conducive to suppressing the spread of disease, but changing the process of disease transmission has no obvious effect on the information dissemination. The analysis also reveals that increasing the information transmission rate or decreasing the information recovery rate can promote the spread of information and inhibit the spread of diseases. In addition, taking preventive behaviors or decreasing the long-distance jump also helps slow the epidemic spreading. (shrink)
New waves in philosophy of technology.Jan Kyrre Berg Olsen Friis,Evan Selinger &Søren Riis (eds.) -2009 - New York: Palgrave-Macmillan.detailsThe volume advances research in the philosophy of technology by introducing contributors who have an acute sense of how to get beyond or reframe the epistemic, ontological and normative limitations that currently limit the fields of philosophy of technology and science and technology studies.
The Anthropology of Sport and Human Movement: A Biocultural Perspective.Jon Entine,Bernd Heinrich,Clifford Geertz,Robert Scott,Greg Downey,Vilma Charlton,Dirk Lund Christensen,Loren Cordain,Søren Damkjaer,Joe Friel,Rachael Irving,Kerrie P. Lewis,Peter G. Mewett,Andy Miah,Timothy Noakes &Yannis P. Pitsiladis (eds.) -2012 - Lexington Books.detailsThe Anthropology of Sport and Human Movement represents a collection of work that reveals and explores the often times dramatic relationship of our biology and culture that is inextricably woven into a tapestry of movement patterns. It explores the underpinning of human movement, reflected in play, sport, games and human culture from an evolutionary perspective and contemporary expression of sport and human movement.
Does the "Morning Morality Effect" Apply to Prehospital Anaesthesiologists? An Investigation Into Diurnal Changes in Ethical Behaviour.Caroline Schaffalitzky,Anne Craveiro Brøchner,Lars Grassmè Binderup &Søren Mikkelsen -2020 -Healthcare 2 (8).detailsThe "morning morality effect"-the alleged phenomenon that people are more likely to act in unethical ways in the afternoon when they are tired and have less self-control than in the morning-may well be expected to influence prehospital anaesthesiologist manning mobile emergency care units (MECUs). The working conditions of these units routinely entail fatigue, hunger, sleep deprivation and other physical or emotional conditions that might make prehospital units predisposed to exhibit the "morning morality effect". We investigated whether this is in fact (...) the case by looking at the distribution of patient transports to hospital with and without physician escort late at night at the end of the shift as a surrogate marker for changing thresholds in ethical behaviour. All missions over a period of 11 years in the MECU in Odense were reviewed. Physician-escorted transports to hospital were compared with non-physician-escorted transports during daytime, evening, and night-time (which correlates with time on the 24 h shifts). In total, 26,883 patients were transported to hospital following treatment by the MECU. Of these, 27.4% (26.9%-27.9%) were escorted to the hospital. The ratio of patient transports to hospital with and without physician escort during the three periods of the day did not differ (p = 1.00). We found no evidence of changes in admission patterns over the day. Thus, no evidence of the expected "morning morality effect" could be found in a prehospital physician-manned emergency care unit. (shrink)
Prediction of Freezing of Gait in Parkinson’s Disease Using a Random Forest Model Based on an Orthogonal Experimental Design: A Pilot Study.Zhonelue Chen,Gen Li,Chao Gao,Yuyan Tan,Jun Liu,Jin Zhao,Yun Ling,Xiaoliu Yu,Kang Ren &Shengdi Chen -2021 -Frontiers in Human Neuroscience 15.detailsPurposeThe purpose of this study was to introduce an orthogonal experimental design to improve the efficiency of building and optimizing models for freezing of gait prediction.MethodsA random forest model was developed to predict FOG by using acceleration signals and angular velocity signals to recognize possible precursor signs of FOG. An OED was introduced to optimize the feature extraction parameters.ResultsThe main effects and interaction among the feature extraction hyperparameters were analyzed. The false-positive rate, hit rate, and mean prediction time were 27%, (...) 68%, and 2.99 s, respectively.ConclusionThe OED was an effective method for analyzing the main effects and interactions among the feature extraction parameters. It was also beneficial for optimizing the feature extraction parameters of the FOG prediction model. (shrink)