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Heterogeneity within MDD has hampered identification of biological markers (e.g., intermediate phenotypes, IPs) that might increase risk for the disorder or reflect closer links to the genes underlying the disease process. The newer characterizations of dimensions of MDD within Research Domain Criteria (RDoC) domains may align well with the goal of defining IPs. We compare a sample of 25 individuals with MDD compared to 29 age and education matched controls in multimodal assessment. The multimodal RDoC assessment included the primary IP (...) biomarker, positron emission tomography (PET) with a selective radiotracer for 5-HT1A ([11C]WAY-100635), as well as event-related functional MRI with a Go/No-go task targeting the Cognitive Control network, neuropsychological assessment of affective perception, negative memory bias and Cognitive Control domains. There was also an exploratory genetic analysis with the serotonin transporter (5-HTTLPR) and monamine oxidase A (MAO-A) genes. In regression analyses, lower 5-HT1A binding potential (BP) in the MDD group was related to diminished engagement of the Cognitive Control network, slowed resolution of interfering cognitive stimuli, one element of Cognitive Control. In contrast, higher/normative levels of 5-HT1A BP in MDD (only) was related to a substantial memory bias toward negative information, but intact resolution of interfering cognitive stimuli and greater engagement of Cognitive Control circuitry. The serotonin transporter risk allele was associated with lower 1a BP and the corresponding imaging and cognitive IPs in MDD. Lowered 5HT 1a BP was present in half of the MDD group relative to the control group. Lowered 5HT 1a BP may represent a subtype including decreased engagement of Cognitive Control network and impaired resolution of interfering cognitive stimuli. Future investigations might link lowered 1a BP to neurobiological pathways and markers, as well as probing subtype-specific treatment targets. (shrink)

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Understanding the evolutionary role of environmentally induced phenotypic variation (i.e., plasticity) is an important issue in developmental evolution. A major physiological response to environmental change is cellular stress, which is counteracted by generic stress reactions detoxifying the cell. A model, stress‐induced evolutionary innovation (SIEI), whereby ancestral stress reactions and their corresponding pathways can be transformed into novel structural components of body plans, such as new cell types, is described. Previous findings suggest that the cell differentiation cascade of a cell type (...) critical to pregnancy in humans, the decidual stromal cell, evolved from a cellular stress reaction. It is hypothesized that the stress reaction in these cells was elicited ancestrally via inflammation caused by embryo attachment. The present study proposes that SIEI is a distinct form of plasticity‐based evolutionary change leading to the origin of novel structures rather than adaptive transformation of pre‐existing characters. (shrink)

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Technological advances in veterinary medicine have produced considerable progress in the diagnosis and treatment of numerous diseases in animals. At the same time, veterinarians, veterinary technicians, and owners of animals face increasingly complex situations that raise questions about goals of care and correct or reasonable courses of action. These dilemmas are frequently controversial and can generate conflicts between clients and health care providers. In many ways they resemble the ethical challenges confronted by human medicine and that spawned the creation of (...) clinical ethics committees as a mechanism to analyze, discuss, and resolve disagreements. The staff of the North Carolina State University Veterinary Hospital, a specialty academic teaching institution, wanted to investigate whether similar success could be achieved in the tertiary care veterinary setting. We discuss the background and rationale for this method, as well as the approach that was taken to create a clinical ethics committee. (shrink)

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While there are many points of opposition between the political philosophies of Marx and Kant, the two can greatly benefit from one another in various ways. Bringing the ideas of Marx and Kant together offers a promising way forward for each view. Most significantly, a powerful critique of capitalism can be developed from their combined thought: Kant’s political philosophy offers a robust idea of freedom to ground this critique, while Marx provides the nuanced understanding of social and political power structures (...) under capitalism that allows this idea of freedom to be properly applied. (shrink)

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The origin of marine invertebrate larvae has been an area of controversy in developmental evolution for over a century. Here, we address the question of whether a pelagic “larval” or benthic “adult” morphology originated first in metazoan lineages by testing the hypothesis that particular gene co-option patterns will be associated with the origin of feeding, indirect developing larval forms. Empirical evidence bearing on this hypothesis is derivable from gene expression studies of the sea urchin larval gut of two closely related (...) but differently developing congenerics, Heliocidaris tuberculata (feeding indirect-developing larva) and H. erythrogramma (nonfeeding direct developer), given two subsidiary hypotheses. (1) If larval gut gene expression in H. tuberculata was co-opted from an ancestral adult expression pattern, then the gut expression pattern will remain in adult H. erythrogramma despite its direct development. (2) Genes expressed in the larval gut of H. tuberculata will not have a coordinated expression pattern in H. erythrogramma larvae due to loss of a functional gut. Five structural genes expressed in the invaginating archenteron of H. tuberculata during gastrulation exhibit substantially different expression patterns in H. erythrogramma with only one remaining endoderm specific. Expression of these genes in the adult of H. erythrogramma and larval gut of H. tuberculata, but not in H. erythrogramma larval endoderm, supports the hypothesis that they first played roles in the formation of adult structures and were subsequently recruited into larval ontogeny during the origin and evolution of feeding planktotrophic deuterostome larvae. (shrink)

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The larval arms of echinoid plutei are used for locomotion and feeding. They are composed of internal calcite skeletal rods covered by an ectoderm layer bearing a ciliary band. Skeletogenesis includes an autonomous molecular differentiation program in primary mesenchyme cells (PMCs), initiated when PMCs leave the vegetal plate for the blastocoel, and a patterning of the differentiated skeletal units that requires molecular cues from the overlaying ectoderm. The arms represent a larval feature that arose in the echinoid lineage during the (...) Paleozoic and offers a subject for the study of gene co-option in the evolution of novel larval features. We isolated new molecular markers in two closely related but differently developing species, Heliocidaris tuberculata and Heliocidaris erythrogramma. We report the expression of a larval arm-associated ectoderm gene tetraspanin, as well as two new PMC markers, advillin and carbonic anhydrase. Tetraspanin localizes to the animal half of blastula stage H. tuberculata and then undergoes a restriction into the putative oral ectoderm and future location of the postoral arms, where it continues to be expressed at the leading edge of both the postoral and anterolateral arms. In H. erythrogramma, its expression initiates in the animal half of blastulae and expands over the entire ectoderm from gastrulation onward. Advillin and carbonic anhydrase are upregulated in the PMCs postgastrulation and localized to the leading edge of the growing larval arms of H. tuberculata but do not exhibit coordinated expression in H. erythrogramma larvae. The tight spatiotemporal regulation of these genes in H. tuberculata along with other ontogenetic and phylogenetic evidence suggest that pluteus arms are novel larval organs, distinguishable from the processes of skeletogenesis per se. The dissociation of expression control in H. erythrogramma suggest that coordinate gene expression in H. tuberculata evolved as part of the evolution of pluteus arms, and is not required for larval or adult development. (shrink)

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As part of a book symposium on Nicholas Vrousalis' Exploitation as Domination: What Makes Capitalism Unjust (2023), S.M.Love argues that only the Kantian view can justify Vrousalis’ argument for the injustice of exploitation, and gives a more detailed account of the injustice of domination within the Kantian framework.

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Socialism has long been thought by many to be the enemy of freedom. Here, I argue that in order to understand the relationship between socialism and freedom, we must have a better idea both of what socialism is and of what it is to have a right to freedom. To start, I argue that the right to freedom is best understood as a right to direct one’s own will in the world consistently with the rights of others to do the (...) same. This Kantian conception of the right to freedom is importantly different from the ubiquitous conception of freedom as negative liberty: with this Kantian conception, one’s right to freedom is limited to directing one’s own will and does not include a right to direct the wills of others. I then argue that socialism, like the right to freedom, is often misunderstood: today, socialists often argue for robustly democratic forms of socialism that are far from the autocratic so-called “socialist” regimes of the last century. With a better understanding of both socialism and the right to freedom, we can see that the right to freedom is indeed compatible with a robustly democratic form of socialism. (shrink)

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The concept of evolvability—the capacity of a population to produce and maintain evolutionarily relevant variation—has become increasingly prominent in evolutionary biology. Paleontology has a long history of investigating questions of evolvability, but paleontological thinking has tended to neglect recent discussions, because many tools used in the current evolvability literature are challenging to apply to the fossil record. The fundamental difficulty is how to disentangle whether the causes of evolutionary patterns arise from variational properties of traits or lineages rather than being (...) due to selection and ecological success. Despite these obstacles, the fossil record offers unique and growing sources of data that capture evolutionary patterns of sustained duration and significance otherwise inaccessible to evolutionary biologists. Additionally, there exist a variety of strategic possibilities for combining prominent neontological approaches to evolvability with those from paleontology. We illustrate three of these possibilities with quantitative genetics, evolutionary developmental biology, and phylogenetic models of macroevolution. In conclusion, we provide a methodological schema that focuses on the conceptualization, measurement, and testing of hypotheses to motivate and provide guidance for future empirical and theoretical studies of evolvability in the fossil record. (shrink)

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The article argues that Kant’s argument for ownership entails a standard of meaningful use by which property regimes can be evaluated: a regime must make it possible for usable objects to be meaningfully used. A particular form of fully communal ownership can satisfy this standard. Further, this form of communal ownership is compatible with Kantian freedom more broadly. I conclude that, if this is so, there is a great deal of space for further consideration of the rightfulness of diverse regimes (...) of ownership and exchange within a Kantian framework. (shrink)

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An incomplete science begets imperfect models. Nevertheless, the target article advocates for jettisoning deep-learning models with some competency in object recognition for toy models evaluated against a checklist of laboratory findings; an approach which evokes Alan Newell's 20 questions critique. We believe their approach risks incoherency and neglects the most basic test; can the model perform its intended task.

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The star-nosed mole is aptly named. Its distinctive snout consists of 22 tendrils ringing a pair of nostrils and, from some angles, the entire setup resembles a misshapen star. The tendrils are fleshy and look a bit like fingers, and, like fingers, they have a certain dexterity. But why? Why does the mole have such a singular appendage as opposed to something more ordinary? What is the function or purpose of this bizarre structure? From the dedicated work of Ken Catania, (...) of Vanderbilt University, and colleagues, it appears that the appendage facilitates rapid handling of small prey items, making it advantageous for an organism whose diet consists of tiny invertebrates. We might therefore hazard that this feature arose evolutionarily because it conferred this benefit. But the matter is difficult to resolve, because current utility does not permit a straightforward inference of a reason for existence. -/- A correction has been published: BioScience, Volume 72, Issue 7, July 2022, Page 708. (shrink)

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“For this reason, since the day we heard about you, we have not stopped praying for you. We continually ask God to fill you with the knowledge of his will through all the wisdom and understanding that the Spirit gives, so that you may live a life worthy of the Lord and please him in every way: bearing fruit in every good work, growing in the knowledge of God, being strengthened with all power according to his glorious might so that (...) you may have great endurance and patience, and giving joyful thanks to the Father, who has qualified you to share in the inheritance of his holy people in the kingdom of light. For he has rescued us from the dominion of darkness and brought us into the kingdom of the Son he loves, in whom we have redemption, the forgiveness of sins.” “And this is my prayer: that yourlove may abound more and more in knowledge and depth of insight, so that you may be able to discern what is best and may be pure and blameless for the day of Christ, filled with the fruit of righteousness that comes through Jesus Christ–-to the glory and praise of God.” 1. (shrink)

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Este ensayo analiza las fuentes de origen medieval y moderno sobre la historia de Ŷarba en el Imāmato rustamí en un intento de aclarar la naturaleza de la relación histórica e historiográfica entre ellos. Se empieza por discutir las fuentes primarias y secundarias disponibles, incluyendo los retos historiográficos que plantean y se presenta a continuación un análisis de las evidencias textuales y arqueológicas que conectan a los rustamíes con Ŷarba. Se intenta después sintetizar las piezas dispersas de la evidencia disponible (...) en el registro histórico con el fin de presentar una imagen más clara de Ŷarba durante el período rustamí. Con base en esta evidencia textual y arqueológica, se argumentará que Ŷarba era hogar de una comunidad ibādí independiente del gobierno en Tāhert durante la mayor parte (si no en su totalidad) de la existencia del Imāmato, distinguiendo así la isla de los alrededores del Ŷarid (en el sur de Túnez), partes de la Ifrīqiya Aglabí y el Ŷabal Nafūsa. Se muestra por último que la evidencia sugiere que esta independencia no era solamente política, sino religiosa. (shrink)

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ObjectiveParenting sensitivity and mutual parent-child attunement are key features of environments that support children’s learning and development. To-date, observational measures of these constructs have focused on children aged 2–6 years and are less relevant to the more sophisticated developmental skills of children aged 7–8 years, despite parenting being equally important at these ages. We undertook a rigorous process to adapt an existing observational measure for 7–8-year-old children and their parents. This paper aimed to: describe a protocol for adapting an existing (...) framework for rating parent-child interactions, determine variations in parents’ sensitive responding and parent-child mutual attunement by family demographics, and evaluate the psychometric properties of the newly developed measure.MethodParent-child dyads completed one home visit, including a free-play observation and parent questionnaire. Dyads were provided with three toy sets: LEGO® Classic Box, Classic Jenga®, and animal cards. The Coding of Attachment-Related Parenting was adapted for use with 7–8-year-old children, and rating procedures were streamlined for reliable use by non-clinician/student raters, producing the SCARP:7–8 Years. Trained staff rated video-recorded observations on 11 behaviors across two domains.ResultsData were available for 596 dyads. Consistently strong inter-rater agreement on the 11 observed behaviors was achieved across the 10-week rating period. Average ICCs were 0.77 for sensitive responding and 0.84 for positive mutuality. These domains were found to be related but distinct constructs. For both domains, average ratings were strongly associated with the main toy used during the observation. Adjusted multivariate linear regression models revealed that less sensitive responding was associated with younger parent, male parent, non-English speaking background, and greater neighborhood disadvantage. Construct validity was demonstrated using six parent-reported psychosocial and parenting measures.ConclusionThe SCARP: 7–8 Years shows promise as a reliable and valid measure of parent-child interaction in the early school years. Toy selection for direct observation should be considered carefully in research and practice settings. (shrink)

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This case is part of a series of case studies used as an exercise within a program on research ethics education. The case involves research on genetic birth defects in a culturally distinct, closed religious community in which elders speak for the community. The case raises ethical issues of informed consent in such a setting; of collaboration with the community; of conflicts between the researchers’ responsibilities to the community as a whole and to individual subjects; of the impact of the (...) researcher’s findings on the practices and values of the community and issues regarding how the researchers share findings with subjects and how the findings are stored. (shrink)

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The American Journal of Bioethics, Volume 12, Issue 5, Page 13-14, May 2012.

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Loving-kindness meditation (LKM) is a popular contemplative mental practice. Its purpose is to cultivate feelings of compassion,love, and prosocial motivation, typically through inner visual imagery and benevolent intentions. Previous studies have revealed evidence for various constructive effects of LKM. It remains an open question, however, whether the effects of LKM are exclusively positive in all practitioners. To tackle this question, we collected 55 microphenomenological interviews (MpIs) reflecting subjective experiences during LKM. Furthermore, we obtained psychological and biological (oxytocin, cortisol) (...) inter-individual difference measures during a nine-month, longitudinal, mental training study. LKM was predominantly described in positive affective terms and associated with cortisol decrease in accordance with the natural diurnal decline, which reflects its generally non-stressful nature. However, five participants reported experiences such as panic, sadness, and fear. Emotional challenge, as indicated by negative word use during MpIs, was linked to lower scores of self-kindness and higher scores of selfcompassionate mindfulness. (shrink)

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This chapter examines Soren Kierkegaard's view about the concept oflove. It suggests that Kierkegaard's ideas aboutlove can be found in Works ofLove, which contains a series of deliberations on the Judeo-Christian commandment tolove one's neighbour as oneself. The chapter also discusses episodes of the story of humanlove in Kierkegaard's earlier works, his Either/Or, Fear and Trembling, and Philosophical Fragments. It also argues that Kierkegaard's philosophical, literary, and theological explorations reveal that (...)love is filled with paradox. (shrink)

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Historically, entities with a vested interest in a product that critics have suggested is harmful have consistently used research to back their claims that the product is safe. Prominent examples are: tobacco, lead, bisphenol A, and atrazine. Research literature indicates that about 80–90 % of studies with industry affiliation found no harm from the product, while only about 10–20 % of studies without industry affiliation found no harm. In parallel to other historical debates, recent studies examining a possible relationship between (...) mercury exposure and autism spectrum disorder show a similar dichotomy. Studies sponsored and supported by industry or entities with an apparent conflict of interest have most often shown no evidence of harm or no “consistent” evidence of harm, while studies without such affiliations report positive evidence of a Hg/autism association. The potentially causal relationship between Hg exposure and ASD differs from other toxic products since there is a broad coalition of entities for whom a conflict of interest arises. These include influential governmental public health entities, the pharmaceutical industry, and even the coal burning industry. This review includes a systematic literature search of original studies on the potential relationship between Hg and ASD from 1999 to date, finding that of the studies with public health and/or industry affiliation, 86 % reported no relationship between Hg and ASD. However, among studies without public health and/or industry affiliation, only 19 % find no relationship between Hg and ASD. The discrepancy in these results suggests a bias indicative of a conflict of interest. (shrink)

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This volume offers an array of newly commissioned essays, addressing the topic oflove in the Christian tradition. Drawn from a range of expert theologians and philosophers in contemporary analytic and non-analytic theology, these essays join current debates within the theology oflove, and aim to propose new avenues for future research. Including the last essay written by Marilyn McCord Adams,Love, Divine and Human deals with a rich variety of issues related to divine and human (...) class='Hi'>love. The broad scope of the book includes divine transcendence and its methodological bearing on the doctrine of divinelove, the nature and scope of divinelove, the interrelation between God'slove and wrath, the plausibility of an impassable God oflove, and the application of various conceptions of divinelove to the problem of divine hiddenness, human ethics, and human free will, among other topics. This unified collection of cutting-edge papers will advance discussion for all those focused on the theology oflove. (shrink)

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Throughout his life, John Tyler Bonner contributed to major transformations in the fields of developmental and evolutionary biology. He pondered the evolution of complexity and the significance of randomness in evolution, and was instrumental in the formation of evolutionary developmental biology. His contributions were vast, ranging from highly technical scientific articles to numerous books written for a broad audience. This historical vignette gathers reflections by several prominent researchers on the greatness of John Bonner and the implications of his work.

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Resumen El presente ensayo explora el alcance que poseen para la pregunta fundamental por la vida buena las reflexiones que Harry Frankfurt ha elaborado acerca de la importancia que atribuimos a ciertas cosas en general, y acerca del amor como una forma señalada en que alguien o algo puede sernos importante. Comienzo examinando las razones por las que, según el autor, resulta imposible ofrecer una respuesta no circular a dicha pregunta, razones que vuelven necesario un modo indirecto de abordarla. A (...) partir de la noción frankfurtiana de importancia propongo a continuación una crítica a la llamada teoría del deseo, el enfoque más influyente en las discusiones actuales en torno al bienestar o la vida buena. Finalmente, y luego de referirme a la necesidad, apuntada por Susan Wolf, de tomar en cuenta el valor objetivo de aquello que nos importa, presento dos consideraciones mediante las cuales intento, con y contra Frankfurt, destacar lo que me parece más valioso de sus ideas acerca del amor.This essay explores the impact of Harry Frankfurt’s reflections on the importance we attach to certain things in general, as well as onlove as a marked way in which something or someone can be important to us, to the fundamental question of the good life. I begin by examining the reasons why, according to the author, it is impossible to offer a non-circular answer to this question, reasons that make necessary an indirect way of approaching it. Starting from the Frankfurtian notion of importance, I then propose a critique of the so-called theory of desire, the most influential approach in current discussions about well-being or the good life. Finally, and after referring to the need, pointed out by Susan Wolf, to take into account the objective value of what matters to us, I present two considerations through which I try, with and against Frankfurt, to highlight what seems most valuable to me of his ideas aboutlove. (shrink)

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As negative information about companies becomes widely available and spreads rapidly through digital communications, understanding consumer reactions to these events and how human perceptions are shaped becomes increasingly important. In this paper, we investigate how consumers’ identification with brands and theirlove for them affect their support for the brand during extremely unethical situations. The results indicate that brand identification both decreases and increases consumers’ ethical judgment following extremely unethical events. Moreover, we find that consumers who are in a (...)love type relationship with the brand proactively shield the brand from other consumers by employing two brand supportive behaviors; sin of omission and brand defense. (shrink)

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Kierkegaard's "Works ofLove" provocatively presses for a reconsideration of impartiality, partiality, and equality. Past readings of this text have typically (1) criticized its focus on the abstract category of "human being," ignoring its attention to distinctiveness and difference; (2) defended it from the charge of abstraction by accenting its treatment of distinctiveness and difference, playing down its assumptions about the "essentially" human; (3) acknowledged its emphases on both essence and difference, arguing that they are incompatible and irreconcilable; or (...) (4) acknowledged both emphases, assuming they are compatible without exploring or accounting for the apparent incompatibility. As a means of resolving this seeming inconsistency, I will focus on Kierkegaard's recommendation of moral blindness and its implications for moral vision, and I will argue that "Works ofLove" contains resources for an understanding of impartiality that allows moral attention to concrete difference. (shrink)

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This article argues that Maurice Merleau-Ponty advances a queer notion oflove. In particular, I argue that his notion oflove as an institution, as a hollow fueled by the imaginary dimension of existence, shows thatlove unhinges petrified ideals of gender. I suggest that the crucial insight to be found in Merleau-Ponty's account oflove is thatlove is a lived openness that invites us to seek out new ways of being.

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In lieu of an abstract, here is a brief excerpt of the content:M. C. DillonLOVE IN WOMEN INLOVE: A PHENOMENOLOGICAL ANALYSIS Despite his sexism, his turgid prose, and his antiquated social conscience, Lawrence is on every bookshelf. This is not merely because of the vicarious erotic entertainment to be found in the saga of John Thomas and Lady Jane, but because Lawrence remains a major guru of romance. We take him seriously, look to him for guidance, (...) measure ourselves against Ursula and Birkin. If he is on our shelves—and his thoughts not far from our pillows—then his ideas starid in need of scrutiny. Women inLove is as much a treatise as a novel: we witness more talking about than making oflove. The agon of ideas engulfs the agon of flesh. Hence, the book suits the present purpose. It cannot be taken as Lawrence's definitive statement onlove—later works, notably Lady Chatterly's Lover, move in different directions—but it is his most philosophical treatment and, I think, most clearly expresses his conceptual framework, the parameters which define and limit his thinking. What he says aboutlove in Women inLove may therefore illumine his depictions of the behavior of lovers in other works. Lawrence is a romantic. In the popular sense of the word he is one who makes of romance or erotic adventure a dominant life value. Lawrence is also a romantic in another sense insofar as he takes the transcendence or unattainability of the other as essential to the project of loving. These two senses are conceptually compatible but existentially in conflict. That is, if one's major undertaking in life is to seek erotic satisfaction, and if one desires only so long as the object is beyond reach, then one has established the groundwork for continual frustration. This, I will try to show, is what Lawrence has done. I Many writers have tried to bring the ideas implicitly present in and constitutive of romanticlove to the level of explicit reflective awareness. 190 M.C.Dillon191 The most successful treatment I know is given by a writer who did not know—or at least did not say—that he was writing about romanticlove. Sartre purports to reveal the inner structures oflove itself—the unqualified, unrestricted essence oflove. As I have tried to show elsewhere,1 he fails at this. But he succeeds admirably in unveiling the inner contradictions of romanticlove. Our project here is to draw upon Sartre's insights: first, to develop a conception of romanticlove, and then to discern the model of Eros which informs Women inLove. The key idea in romanticlove is transcendence. Something is transcendent when it is beyond me, when I cannot adequately prehend it conceptually or master it with my will. The role of transcendence in romanticlove is demonstrated clearly in Denis de Rougemont's book onLove in the Western World.2 There he shows that Tristan's passion for Iseult is directly proportional to her distance from him: he is increasingly attracted as she becomes further removed. On the other hand, when through various deeds of gallantry and subterfuge, he succeeds in winning her to his side, he loses interest and must create circumstances which put her again beyond his reach. The culmination of romanticlove, according to de Rougemont, is death—it sets the other absolutely beyond reach. It also arrests and preserves at their apices the youth and beauty of the lovers and the intensity of the erotic relationship. It is, I believe, this complex of ideas that led Kierkegaard to this cynical reflection on the nature of romanticlove: "When two beings fall inlove with one another and begin to suspect that they were made for each other, it is time to have the courage to break it off; for by going on they have everything to lose and nothing to gain."3 The same idea, qualified by increased optimism, underlies Stendhal's notion of crystallization in his book OnLove.*Love is predicated on the attribution of perfection to the beloved. Just as a plain bough emerges from the salt-saturated waters of the Salzburg mines encrusted with beautiful crystals... (shrink)

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This chapter contains sections titled: Upbuilding Discourses in Various Spirits Works OfLove: Some Christian Deliberations in the Form of Discourses Christian Discourses The Crisis and a Crisis in the Life of an Actress The Point of View for My Work as an Author Three Godly Discourses further reading.

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Modern commentators like Allen Wood have noted that for Kant there “is a basic tension in human nature between loving people and respecting them.”Love is a threat to pure morality insofar aslove is an empirical inclination and any will determined by such an inclination is unfree. In this paper, I begin by exploring why Kant thinks thatlove is a threat to moral freedom. Drawing on the insights of Dietrich von Hildebrand, I propose instead an (...) analysis oflove as “value-response.” I argue that a more complete phenomenological analysis of the nature of human affectivity (as fundamentally intentional and responsive) exposes a serious defect in Kant’s moral psychology, particularly his unreasonable denial of the compatibility of higher-order affectivity and human freedom. Drawing on von Hildebrand’s notion of “cooperative freedom,” I argue that not only is a higher-order spiritual affectivity compatible with freedom and morality, but it is essential to it. (shrink)

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A review of economic thought since the sixteenth century reveals two streams of economic discourse, dirigisme and laissez-faire. Starting with the mercantilists, dirigiste approaches to economics embrace the real-world complexity of commodities that often differ greatly in attributes that are growth- and rent- augmenting. Most importantly, this means that free trade is likely to be polarising: it concentrates growth- and rent-augmenting commodities in countries that already enjoy a head start in these commodities. Advanced countries, therefore, support laissez-faire, while lagging countries (...) tend to support dirigisme. In order to rationalise their laissez-faire stance, advanced countries began developing a new economic discourse that strips commodities of their complexity. The foundations for this ideological reconstruction of economics were first laid by Adam Smith; this process eventually reached its climax with the neoclassical economists who stripped commodities down to one attribute: their capital intensity. In opposition to this laissez-faire economics, other writers, supportive of the interests of lagging countries, brought complexity back into their economic discourse; they argued that lagging countries had a fighting chance of catching up to advanced economies only by indigenising a growing array of growth- and rent-augmenting commodities. (shrink)

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The manifold phenomena oflove exhibited in diverse human societies during different periods of recorded history are rooted in biological features of human beings. The human procreative urge among women is natural to our species. Maternallove is rooted in mammalian nature. The ideallove of a mother for her child is a common transcultural paradigm of selflessness. This chapter first examines the biological roots oflove and subsequently to the social constraints within which its various (...) forms are possible. It then discusses the multiple kinds of possible objects oflove and the threads connecting them, and explains the framework of moral, social, and legal norms within which humanlove is realized.Love is a paradigm of a developing emotion. Being inlove is the natural sequel to falling inlove. It involves wanting to be with the person loved, a strong desire to please, to share experience, and to delight in shared experiences. (shrink)

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In a recent article1 the psychiatrist George Devereux reached the following conclusion about fr. 31: Sappho as a ‘masculine lesbian’ experiences ‘a perfect, “text-book case”, anxiety attack’, elicited by ‘alove-crisis’, viz. by the presence of a male rival for the attention of Sappho's favourite girl. He then sums up: ‘In fact, even if there existed no explicit tradition concerning Sappho's lesbianism, her reaction to her male rival would represent for the psychiatrist prima facie evidence of her perversion’.

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