Blood and immune cell engineering: Cytoskeletal contractility and nuclear rheology impact cell lineage and localization.Jae-Won Shin &Dennis E. Discher -2015 -Bioessays 37 (6):633-642.detailsClinical success with human hematopoietic stem cell (HSC) transplantation establishes a paradigm for regenerative therapies with other types of stem cells. However, it remains generally challenging to therapeutically treat tissues after engineering of stem cells in vitro. Recent studies suggest that stem and progenitor cells sense physical features of their niches. Here, we review biophysical contributions to lineage decisions, maturation, and trafficking of blood and immune cells. Polarized cellular contractility and nuclear rheology are separately shown to be functional markers of (...) a hematopoietic hierarchy that predict the ability of a lineage to traffic in and out of the bone marrow niche. These biophysical determinants are regulated by a set of structural molecules, including cytoplasmic myosin‐II and nuclear lamins, which themselves are modulated by a diverse range of transcriptional and post‐translational mechanisms. Small molecules that target these mechanobiological circuits, along with novel bioengineering methods, could prove broadly useful in programming blood and immune cells for therapies ranging from blood transfusions to immune attack of tumors. (shrink)
Making More Fundamental Questions in a Community of Inquiry.Jae-Won Son -2008 -Proceedings of the Xxii World Congress of Philosophy 52:81-86.detailsIt is questions that children need to do higher-order thinking in a community of inquiry. There, more fundamental questions should be asked with some efforts to understand clearly and analyze the given texts. The initial questions should be elaborated into more fundamental ones through dialogues and discussions, and the process may be changed by the given conditions and contexts. In this paper, I show by some real cases how teachers can help children make more fundamental questions in a community of (...) inquiry. (shrink)
Dynamic Capabilities and an ESG Strategy for Sustainable Management Performance.Yi Liang,Min Jae Lee &Jin Sup Jung -2022 -Frontiers in Psychology 13.detailsThis research explores the dynamic capabilities required for firms to implement environmental, social, and governance strategies, and investigates sustainable management performance that can be created based on them. By using dynamic capabilities theory, we integrate sustainable management and the ESG literature to suggest a research model and identify the factors that act as the catalysts achieving sustainability. The data used for the analysis were collected from 78 firms listed on the Korea Exchange with assets totaling more than 2 trillion Korean (...) won. In this study, the partial least squares structural equation model is applied. We found that absorptive capability and adaptive capability significantly affect sustainable management performance through implementation of the ESG strategy as a mediating variable. In particular, a firm’s implementation of an ESG strategy is a significant determinant that impacts sustainable management performance. We also believe our model contributes to the current knowledge by filling several research gaps, and our findings offer valuable and practical implications not only for achieving sustainable growth but also for creation of competitive advantage. (shrink)
The formation and development of Won-Hyo(元曉)’s reconciliatory philosophy(和諍哲學) - Centering on the Mun(門)-division thinking -. 박태원 -2017 -Journal of the New Korean Philosophical Association 90:239-262.details원효사상의 체계와 내용을 관통하는 원리, 원효철학의 모든 것을 직조해 내는 근본원리, 원효의 모든 통찰을 수렴하는 상위원리는 ‘통섭’이다. 통섭과 화쟁은 특히 밀접한 관계를 맺고 있다. 화쟁의 꽃이 필 때라야 통섭의 열매가 맺는다. 원효의 화쟁사상은 그 시대 불교사상계의 분열적 혼란을 해결하기 위한 미시 해석학적 방법이다. 이 글에서는 원효 화쟁철학에서 주목되는 ‘문門구분의 사유방식’을 중심으로 화쟁철학의 형성과 발전단계를 추적해 보았다. ‘문門구분을 통한 화쟁’을 중심에 두고, 다른 두 축인 ‘모든 쟁론의 인식적 토대에서 자유로울 수 있는 마음지평(一心) 열기’와 ‘언어 환각에서 풀려나 언어를 사용하기’를 양 옆에 세운 (...) 후, 이 세 축이 서로 맞물려 힘을 보태면서 끝없이 상승해 가는 구도. - 이것이 원효의 화쟁에 대한 필자의 독법이다. 통섭이나 화쟁의 통찰을 전개할 때 구사하는 ‘문門구분’의 ‘문門’은, ‘일련의 타당한 인과계열’ ‘조건적으로 타당한 의미맥락’을 의미하는 경우가 대다수이다. 원효는 이 ‘문門 구분 사유방식’을 『대승기신론』의 일심이문一心二門에서 포착하여 확대, 발전시켜 간 것으로 보인다. 원효는 기신론의 ‘이문二門 구별’에서 ‘문門 구별의 연기적 사유’를 포착한 후 다양한 유형의 이문二門구별로 발전시킨다. 그리고 이를 통해 이론과 주장들을 조건적으로 이해함으로써 사실에 부합하는 정확한 이해에 접근하려 한다. 아울러 다양하게 분석한 이문二門들의 ‘통섭通攝적 관계’를 밝힘으로써, 배타적으로 엇갈리는 이론과 주장들이 화해할 수 있는 자리를 마련한다. 이렇게 볼 때 연기적 사유의 원효적 유형인 ‘문門구별의 사유방식’은 크게 세 단계에 걸쳐 발전하고 있다. 첫 단계는 기신론의 ‘진여/생멸 이문二門 구별’에서 문門 구별의 사유방식에 눈뜬 것이며, 두 번째 단계는 이 ‘문門구별의 사유방식’을 활용하여 ‘문二門 구별의 다양한 방식들’을 전개하는 것이고, 세 번째 단계는 ‘문門구별의 사유방식’을 통해 상이한 이론과 관점들이 ‘서로 열고 서로 안을 수 있는’ 통섭通攝과 화쟁和諍의 공간을 마련하는 것이다. 그리고 원효의 ‘문門구별 사유방식’은 이 세 번째 단계를 발전의 정점으로 삼는다. (shrink)
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Character ethics and the New Testament: moral dimensions of Scripture.Robert L. Brawley (ed.) -2007 - Louisville, Ky.: Westminster John Knox Press.detailsThroughout the New Testament, the Gospel stories, the sayings of Jesus, and the writings of Paul not only teach a way of life that requires individuals to be moral but they demonstrate how. In biblical studies, character ethics has been one of the fastest-growing areas of interest. Whereas ethics usually studies rules of behavior, character ethics focuses on how people are formed to be moral agents in the world. Here editor Robert Brawley presents the most up-to-date academic work in New (...) Testament character ethics, covering topics throughout the Gospels and Paul, as well as focusing on the essential topics of forgiveness, reconciliation, politics, and peacemaking. In addition to Brawley, contributors are C. Clifton Black, Neil Elliott, Jens Herzer, L. Ann Jervis, Sylvia C. Keesmat, Jae Won Lee, J. Clinton McCann Jr., Elna Mouton, C. Drew Smith, Glen Stassen, Willard M. Swartley, Allen Verhey, and Jinseong Woo. (shrink)
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Dialogues on Disability: Shelley Tremain Interviews Cecilea Mun.Cecilea Mun -2020 -Biopolitical Philosophy (February):X.detailsSecond, follow-up interview of Cecilea Mun by Shelley Tremain.
Locke’s Philosophy of Education: The Empire of Habit and Paradox of Liberty.Jae Yeong Lee -2020 -Modern Philosophy 15:5-43.details로크 철학의 주된 내용인 인간 본성 백지설, 원자적 개인관, 반원죄설, 관용론, 교육론은 서로 긴밀하게 연결되어 있다. 순응성 테제(malleability thesis)로 요약할 수 있는 로크의 교육론은 인간 본성 백지설과 인격 동일성 이론에 의해 뒷받침된다. 그 중에서 특히 로크 철학의 상징처럼 되어 버린 인간 본성 백지설은 상당히 왜곡되고 과장되었다는 비판을 받아 왔다. 로크가 조기 교육에서 강조하는 습관은 너무나 강력해서 아이를 습관의 제국(the empire of habit)의 신하가 되게 한다. 아이의 이성 자체가 보호자와 공동체가 요구하는 습관적 사고와 행동의 토대 위에 형성된다. 여기서 다른 사람들의 의견에 (...) 철저하게 의존하는 것이 아이를 자유롭게 한다는 ‘자유의 역설’(Paradox of Liberty)이 성립된다. 자유는 훈련의 산물이고 아이는 보호자에 의해 제시된 공동체의 덕의 모델에 따르기를 선택하는 행위자라는 의미에서만 자유롭다. 로크 교육론의 구축된 자유에 비추어 볼 때 자연적 자유는 어떤 의미를 갖는지 결코 분명하지 않다. (shrink)
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Ethics and trauma in contemporary British fiction.Susana Onega Jaén &Jean-Michel Ganteau (eds.) -2011 - New York: Rodopi.detailsINTRODUCTION JEAN-MICHEL GANTEAU AND SUSANA ONEGA The rise of trauma theory in the critical field is a recent phenomenon associated with the revival of ...
Toward a pedagogy of humility as experience.Jae Park &Anselmo Bae -2023 -Educational Philosophy and Theory 55 (2):195-206.detailsHumility is widely regarded as a moral excellence and telos, hence, openly inculcated-instructed. Character education in and for humility, however, sits uncomfortably against today’s pedagogical maxims such as self-esteem and self-assertiveness. This article looks into this and other tensions from the perspective of humility as experience (phenomenon) instead of humility as goal. Surveying humility qua experience can help us to understand how the mind directs toward objects of cognition with their content, meaning and axiology. Husserl’s phenomenology and its theory of (...) intuition suggests that humility is a personal belief (doxa) that moral agents construct out of their lived-experiences. Through iterations of similar lived-experiences, humility can become a habitus and, arguably, episteme. This process is detailed by intersecting experience of humility with intentionality, phenomenological reduction, and intersubjectivity. It is argued that, in contemporary education, ‘experience’ is widely accepted as learning content and teaching method. Humility as experience has significant implications for the main schools in curriculum studies, namely traditionalists, conceptualists and phenomenologists. This article claims that inculcating humility poses ethical challenges, and the role of education should instead be to explain and present to learners the phenomenological reality of humility. (shrink)
Schizophrenia, Temporality, and Affection.Jae Ryeong Sul -2022 -Phenomenology and the Cognitive Sciences 21 (4):927-947.detailsTemporal experience and its radical alteration in schizophrenia have been one of the central objects of investigation in phenomenological psychopathology. Various phenomenologically oriented researchers have argued that the change in the mode of temporal experience present in schizophrenia can foreground its psychotic symptoms of delusion. This paper aims to further the development of such a phenomenological investigation by highlighting a much-neglected aspect of schizophrenic temporal experience, i.e., its non-emotional affective characteristic. In this paper, it denotes the type of an experience (...) wherein an afflicted individual experiences a pervasive pull or attraction coming from the past, present, and future. By employing Husserl’s account of affection, I argue that such an affectively prominent temporal experience is not yet another abnormality that happens to be present in schizophrenia. Instead, it is indicative of the core disturbance that underpins the schizophrenic temporal mode of experience. I identify such a disturbance as ‘affective modification dysfunction’ and employ it as a core concept with which I synthesize and organise heterogeneous components of schizophrenic temporal experience in their conceptual unity. For the sake of clear description, I organise those components into the following categories: 1.) Time Stop 2.) Ante-festum 3.) Déjà vu/vécu and 4.) Time Fragmentation. I conclude by demonstrating how approaching schizophrenic temporal experience from its affective dimension can further help us better understand its pre-psychotic phase known to precipitate schizophrenic primary delusion, i.e., delusional mood. (shrink)
The structure of silence in depression.Jae Ryeong Sul -2025 -Synthese 205 (2):1-23.detailsSilence has been a relatively neglected phenomenon despite its significance in psychiatric research. Acknowledging this oversight, there has been a recent move towards systematically describing the first-personal experience of silence in mental disorders within the field of philosophy of psychiatry. This paper contributes to this research effort by highlighting the underexplored interpersonal aspect of silence crucial for both psychopathological and therapeutic research. More specifically, I develop the interpersonal aspect of distressing silence associated with depression, recently coined as ‘empty silence’. Complementing (...) its original analysis, I argue that this distressing silence not only involves the loss of linguistic agency but also the loss of social agency. Having established this claim, I situate it within the wider research context and open an ethical dimension to the current analysis. I explore this by identifying a therapeutic silence others can establish for an individual undergoing a severe depressive episode. I provisionally term it ‘undemanding silence’ and argue that this form of silence can help restore the loss of social agency by providing a distinct form of social affordance that depressed individuals can easily realise at their own pace. (shrink)
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Constructing ‘others’ and a wider ‘we’ as emotional processes: A case of South Korea in times of crisis.Jae-Eun Noh -2022 -Thesis Eleven 170 (1):43-57.detailsThis article examines how growing fears, insecurities and uncertainties during the COVID-19 pandemic have prompted an emotional distance from others. The aim is to explore how global solidarity and nationalism are challenged and constructed as collective emotional processes concerning ‘others’. Drawing on social theories of emotions during crises and emotions towards others, this study looks at policy decisions around vaccines and health services and their associated emotions in the context of Korea, which has a relatively small migrant population and a (...) short history of supporting people in lower-income countries. The study finds that the COVID-19 pandemic has strengthened nationalism, both ethnic nationalism and cosmopolitan nationalism. This points to the need to highlight global norms such as human rights and justice and cultivate foundational emotions such as empathy and compassion. This article suggests paying attention to the role of emotions in generating othering practices and developing global solidarity. (shrink)
Curriculum studies as post-oriental text: Entering into a transgressive complex conversation for postcolonial transnational curriculum studies.Jae Hong Joo &Young Chun Kim -forthcoming -Educational Philosophy and Theory.detailsThis article suggests a new field of curriculum studies called “Curriculum Studies as Post Oriental Text” as an emerging inquiry of the global postcolonial curriculum studies. Based on readings of postcolonial theories, analysis of empirical studies of Asian curriculum practices, and author’s longtime postcolonial observation of South Korean curriculum scholarship, the article discusses five topics in details with a hope that more diverse and transgressive inquiry of Asian postcolonial curriculum studies will be developed and expanded among scholars of education in (...) Asia. (shrink)
The Impact of Moral Emotions on Cause-Related Marketing Campaigns: A Cross-Cultural Examination.Jae-Eun Kim &Kim K. P. Johnson -2013 -Journal of Business Ethics 112 (1):79-90.detailsThis research was focused on investigating why some consumers might support cause-related marketing campaigns for reasons other than personal benefit by examining the influence of moral emotions and cultural orientation. The authors investigated the extent to which moral emotions operate differently across a cultural variable (US versus Korea) and an individual difference variable (self-construal). A survey method was utilised. Data were collected from a convenience sample of US ( n = 180) and Korean ( n = 191) undergraduates. Moral emotions (...) significantly influenced purchase intention for a social-cause product. The influence of an ego-focused moral emotion (i.e., pride) on purchase intention was greater for US than Korean participants. The influence of another-focused moral emotion (i.e., guilt) on purchase intention was greater for high-interdependent participants than for low-interdependent participants. The findings of this research provide important and relevant implications to marketers and policy makers in developing persuasive messages and customer relationship programmes. (shrink)
The structure of pluralism: on the authority of associations.Muñiz Fraticelli &Victor Manuel -2014 - Oxford, United Kingdom: Oxford University Press.detailsThe structure of pluralist arguments -- The inadequacy of multiculturalism -- The incompatibility of subsidiarity -- Associative democracy and the corporatist temptation -- Two conceptions of sovereignty -- A positivist pluralism? -- Law as intelligibility -- Pluralist authority -- This unity of life and action -- The personality of associations -- Property, personality, and public justification -- The spectre of intractability.
An Experience of Machine-Based Images by the Autonomy of Computing System.Jae-Joon Lee -2008 -Proceedings of the Xxii World Congress of Philosophy 12:47-54.detailsContemporary production of machine-based images relay gradually on the autonomy of computing machines. Autonomous computing machines require the interaction with users like Human-Computer-Interaction technology and other interface technologies, especially computing machine-based images must also ask for viewer as an inter-actor, viewer’s participations. Whether this interaction of viewer-user is with machines or with images, if it is an interaction with each individual that have autonomy or self-organization, its interaction will be the interaction of each ecosystem. And the forms of this environmental (...) interaction are an exchange of energy in natural ecosystem or aesthetic communication in art. Hence the aesthetics of future autonomous machine-based images need to focus on a number of mesh-works and the ways of interactions between the aesthetic individuals and their structures, i.e. aesthetic ecosystems. (shrink)