Movatterモバイル変換


[0]ホーム

URL:


PhilPapersPhilPeoplePhilArchivePhilEventsPhilJobs

Results for 'Haig Utidjian'

201 found
Order:

1 filter applied
  1.  28
    Armenia. Art, Religion, and Trade in the Middle Ages, edited by Helen C. Evans, New York: The Metropolitan Museum of Art 2018 Christina Maranci,The Art of Armenia. An Introduction, New York: Oxford University Press 2018. [REVIEW]HaigUtidjian -2019 -Convivium 6 (2):147-150.
    No categories
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark  
  2.  106
    Haig’s ‘strange inversion of reasoning’ and Making sense: information interpreted as meaning.DavidHaig &Daniel Dennett -unknown
    DavidHaig propounds and illustrates the unity of a radically revised set of definitions of the family of terms at the heart of philosophy of cognitive science and mind: information, meaning, interpretation, text, choice, possibility, cause. This biological re-grounding of much-debated concepts yields a bounty of insights into the nature of meaning and life. An interpreter is a mechanism that uses information in choice. The capabilities of the interpreter couple an entropy of inputs to an entropy of outputs is (...) dispelled by observation. The second entropy is dispelled. I propose that an interpreter’s response to inputs meaning of the information for the interpreter. In this conceptual framework, the mechanisms of interpreters provide the much-debated link between Shannon information and semantics. (shrink)
    No categories
    Direct download(4 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  3.  7
    Judging Democracy: The New Politics of the High Court of Australia.Haig Patapan -2000 - Cambridge University Press.
    The High Court is taking an increasingly important role in shaping the contours of democracy in Australia. In deciding fundamental democratic questions, does the Court pursue a consistent and overarching democratic vision? Or are its decisions essentially constrained by institutional and practical limitations? Judging Democracy, first published in 2000, addresses this question by examining the Court's recent decisions on human rights, citizenship, native title and separation of powers. It represents the first major political and legal examination of the Court's new (...) jurisprudence and the way it is influencing democracy and the institutions of governance in Australia. A foreword to the book has been written by the former Chief Justice of the High Court, Sir Anthony Mason. (shrink)
    Direct download  
     
    Export citation  
     
    Bookmark   4 citations  
  4.  18
    A critical study in method.Haig Khatchadourian -1967 - The Hague,: Martinus Nijhoff.
    CHAPTER ONE PHILOSOPHICAL ANALYSIS: A GENERAL DISCUSSION The terms 'analysis' and 'analyse' are used in all sorts of ways in ordinary discourse and in ...
    No categories
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  5.  23
    The Coherence Theory of Truth: A Critical Evaluation.Haig A. Khatchadourian -2010 - Wipf and Stock Publishers.
    Haig Khatchadourian is Emeritus Professor of Philosophy at the University of Wisconsin-Milwaukie. He received his PhD in philosophy from Duke University and has been awarded several prizes for poetry and literary essays. In 1973 he received the Outstanding Educator of America Award.
    Direct download  
     
    Export citation  
     
    Bookmark  
  6.  38
    Art and the Aesthetic, An Institutional Analysis.Haig Khatchadourian -1979 -Noûs 13 (1):113-117.
    No categories
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark   7 citations  
  7. Condiciones físicas óptimas para el goce del arte visual.Haig Khatchadourian -1973 -Dianoia 19 (19):89-103.
    No categories
     
    Export citation  
     
    Bookmark  
  8.  11
    Philosophy of Language and Logical Theory: Collected Papers.Haig Khatchadourian -1995 - Upa.
    The content of this book provides a unified and coherent treatment of a number of important issues in the philosophy of language and logical theory.
    Direct download  
     
    Export citation  
     
    Bookmark  
  9. Words, Signs, Signals, and Symbols.Haig Khatchadourian -1969 -Philosophical Forum 1 (4):493.
  10. Science in revolt.Haig M. Mosditchian -1968 - Nicosia, Cyprus: Nicosia, Cyprus.
  11. An Abductive Theory of Scientific Method.BrianHaig -2018 - In Brian D. Haig,Method Matters in Psychology: Essays in Applied Philosophy of Science. Cham: Springer Verlag.
    No categories
     
    Export citation  
     
    Bookmark   2 citations  
  12.  82
    Grounded theory as scientific method.Brian D.Haig -1995 -Journal of Philosophy of Education 28 (1):1-11.
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark   4 citations  
  13.  23
    The Literary Work of Art: An Investigation on the Borderlines of Ontology, Logic, and Theory of Literature.Haig Khatchadourian -1974 -Journal of Aesthetics and Art Criticism 33 (2):217-220.
  14.  9
    Community and Communitarianism.Haig Khatchadourian -1999 - Peter Lang Incorporated, International Academic Publishers.
    Community and Communitarianism presents - and defends in detail - a care-centered ideal of a good and moral community: a form of social organization imbued with the virtues of a care-centered ethic, such as cooperation (in «teleological communities, » cooperation in the realization of communal goals); mutual concern and solidarity; sympathy and empathy; benevolence; a spirit of sacrifice; and affection, love, and caring. It is argued that a care-centered ethic, hence a care-centered community, needs to be constrained and fortified by (...) equal respect for the participants' basic human right to be treated as moral subjects, together with fair and just treatment. Besides contributing to social philosophy, the book contributes significantly to ethics. (shrink)
    Direct download  
     
    Export citation  
     
    Bookmark   2 citations  
  15. Tests of Statistical Significance Made Sound.BrianHaig &Brian D.Haig -2018 - In Brian D. Haig,Method Matters in Psychology: Essays in Applied Philosophy of Science. Cham: Springer Verlag.
    No categories
     
    Export citation  
     
    Bookmark  
  16. Acerca de.Haig Khatchadourian -1971 -Dianoia 17 (17):89.
    No categories
     
    Export citation  
     
    Bookmark  
  17.  22
    Vagueness, Meaning, and Absurdity.Haig Khatchadourian -1965 -American Philosophical Quarterly 2 (2):119 - 129.
    Direct download  
     
    Export citation  
     
    Bookmark  
  18.  23
    A New Theory of Beauty.Haig Khatchadourian -1975 -Journal of Aesthetics and Art Criticism 35 (3):361-363.
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  19.  34
    The Philosophy of Quantitative Methods: Understanding Statistics.Brian D.Haig -2018 - Oup Usa.
    The Philosophy of Quantitative Methods undertakes a philosophical examination of a number of important quantitative research methods within the behavioral sciences in order to overcome the non-critical approaches typically provided by textbooks. These research methods are exploratory data analysis, statistical significance testing, Bayesian confirmation theory and statistics, meta-analysis, and exploratory factor analysis. Further readings are provided to extend the reader's overall understanding of these methods.
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark   2 citations  
  20.  34
    Imperatives and their Logics.Haig Khatchadourian -1978 -Philosophy and Phenomenological Research 39 (2):283-284.
    No categories
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  21.  265
    John Locke’s “Unease”: The Theoretical Foundation of the Modern Separation of Church and State.Haig Patapan &Jeffrey Sikkenga -2024 -Political Theory 52 (5):808-833.
    John Locke is acknowledged to be one of the theoretical founders of the separation of church and state, a distinguishing feature of modern liberal democracies. Though Locke’s arguments for the merits of such separation have been subject to extensive investigation, his argument for its feasibility has remained relatively unexamined. This article argues that Locke was confident that separation of church and state can successfully be implemented in all times and places because of his epistemological and psychological insights that human beings (...) are moved to act by unease and that separating church and state removes the unease that causes religiously based political instability. We conclude by noting that Locke’s understanding of unease is foundational for his larger ambition to secure political liberty. (shrink)
    Direct download(4 more)  
     
    Export citation  
     
    Bookmark  
  22. Exploratory Factor Analysis, Theory Generation, and Scientific Method.BrianHaig -2018 - In Brian D. Haig,Method Matters in Psychology: Essays in Applied Philosophy of Science. Cham: Springer Verlag.
    No categories
     
    Export citation  
     
    Bookmark  
  23. Verse: Exhibition.Mabel GeorgeHaig -1966 -Pacific Philosophical Quarterly 47 (1):42.
    No categories
     
    Export citation  
     
    Bookmark  
  24.  23
    A Defence of Realism.Haig Khatchadourian -1975 -Proceedings of the XVth World Congress of Philosophy 5:549-553.
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark  
  25.  9
    Existence.Haig Khatchadourian -1984 -Critica 16 (47):33-58.
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark  
  26. Language and Commitment.Haig Khatchadourian -1971 -Philosophical Forum 3 (1):62.
  27. Lenguaje y habla como institución y como práctica.Haig Khatchadourian -1979 -Teorema: International Journal of Philosophy 9 (1):5.
     
    Export citation  
     
    Bookmark  
  28.  11
    Objects and Qualities.Haig Khatchadourian -1969 -American Philosophical Quarterly 6 (2):103 - 115.
  29.  5
    On Three Forms of Philosophical Analysis.Haig Khatchadourian -1960 -Atti Del XII Congresso Internazionale di Filosofia 5:263-269.
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark  
  30. Truth as identity of proposition and fact.Haig Khatchadourian -1966 -Theoria 32 (2):144.
    No categories
     
    Export citation  
     
    Bookmark  
  31.  11
    Vagueness, Verifiability and Metaphysics.Haig Khatchadourian -1965 -Foundations of Language 1 (4):249-267.
  32.  100
    "Lord Over the Children of Pride": The Vaine-Glorious Rhetoric of Hobbes's Leviathan.Haig Patapan -2000 -Philosophy and Rhetoric 33 (1):74-93.
    In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Rhetoric 33.1 (2000) 74-93 [Access article in PDF] "Lord Over the Children of Pride": The Vaine-Glorious Rhetoric of Hobbes's LeviathanHaig Patapan Hobbes claimed in the Leviathan that he had, by "industrious meditation," discovered the Principles of Reason that would allow Commonwealths to be everlasting. He claimed, in other words, to have solved the political problem (1968, chap. 30, 378). All that was now required was (...) to have his work "fall in the hands of a Soveraign" who would, "in protecting the Publique teaching of it, convert this Truth of Speculation, into Utility of Practice" (chap. 31, 408). Accordingly, an important element of his political solution was the Leviathan itself, a work that would instruct the people in the Essential Rights of Sovereignty (chap. 30, 379). It would seem, then, that the Leviathan is an essential combination of these two aspects of Hobbes's endeavour; it is a work that is intended to reveal and persuade. Therefore, it is appropriate to evaluate his undertaking, not only in terms of its teaching, but also in the success of its rhetorical ambition. 1I argue in this paper that Hobbesian rhetoric is fundamentally determined by his political theory, in particular, by his discovery of the problem of vaine-glory, or pride. Pride poses a political problem because it is a passion that produces an unrealistic estimation of our abilities and therefore ultimately leads to deadly struggles and war. Hobbesian political science attempts to overcome the problem of pride by instituting a Leviathan, a lord over the children of pride. Once we see the nature of the political problem as Hobbes presents it and his proposed solution, the rhetorical character of Hobbes's writings becomes clearer.The extent to which Hobbes relies upon, and in crucial respects departs from, the traditional rhetoric that drew upon Artistotle's Rhetoric and subsequently Cicero's De Inventione and Quintilan's Institutio Oratoria is a complex question. 2 In this paper, I explore the rhetoric of the Leviathan, especially its first part, "On Man," to distinguish the Aristotelian and Ciceronian tradition from what I call Hobbes's Euclidean rhetoric. More [End Page 74] specifically, I argue that the structure and movement of part 1 of the Leviathan can be better understood when it is seen as a direct assault on human pride, a stripping away of all claims that may lead to vaine-glory. It is a step-by-step, Euclidean reductio that attempts to curb the readers' passion of glorying. This argument about the rhetorical character of the first part of the Leviathan has important theoretical consequences: it suggests that Hobbes's influential formulation of power, rights, and justice also had a profoundly rhetorical character.But how persuasive is Hobbes's rhetoric? For reasons noted above, this question goes to the heart of his political theory. The final part of this paper explores the efficacy of the Hobbesian rhetoric of pride and therefore of Hobbesian science. I argue that the rhetorical descent in the first part of the Leviathan, where the truth about human weakness is revealed to the proud, is simultaneously an ascent that acknowledges independence and self-sufficiency of human beings as "self-makers." Thus I argue that, rather than overcoming the problem of pride, Hobbesian political science re-founds it on the bases of rights and the promise of unlimited progress through science and commerce: Hobbes's rhetoric reformulated, but did not solve, the problem of pride. The problem of pride The importance of pride for Hobbes's psychology and political theory is evident from the title and frontispiece of the Leviathan. 3 The Leviathan, according to the Old Testament, is a creature of the Lord, set over the children of pride (Job 41:34). In Hobbes's reformulation, the Leviathan is an artificial body, made by the "Art of man," whose business is Salus Populi or the peoples' safety (1968, "Introduction," 81). Thus, from the beginning, the revolutionary flavour of Hobbes's enterprise is made evident: Man replaces God; pride is a problem of safety... (shrink)
    Direct download(7 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  33.  13
    Investigating face recognition with an image processing computer.Nigel D.Haig -1986 - In H. Ellis, M. Jeeves, F. Newcombe & Andrew W. Young,Aspects of Face Processing. Martinus Nijhoff. pp. 410--425.
  34. Philosophical Naturalism and Scientific Method.BrianHaig -2018 - In Brian D. Haig,Method Matters in Psychology: Essays in Applied Philosophy of Science. Cham: Springer Verlag.
    No categories
     
    Export citation  
     
    Bookmark  
  35. Scientific realismwith correspondence truth: A reply to Asay (2018).Brian D.Haig &Denny Borsboom -2018 -Theory and Psychology 28 (3):398-404.
    Asay (2018) criticizes our contention that psychologists do best to adhere to a substantive theory of correspondence truth. He argues that deflationary theory can serve the same purposes as correspondence theory. In the present article we argue that (a) scientific realism, broadly construed, requires a version of correspondence theory and (b) contrary to Asay’s suggestion, correspondence theory does have important additional resources over deflationary accounts in its ability to support generalizations over classes of true sentences.
     
    Export citation  
     
    Bookmark  
  36.  24
    The Foundations of Aesthetics.Haig Khatchadourian -1979 -Journal of Aesthetics and Art Criticism 38 (2):193-195.
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark  
  37.  121
    The strategic gene.DavidHaig -2012 -Biology and Philosophy 27 (4):461-479.
    Abstract Gene-selectionists define fundamental terms in non-standard ways. Genes are determinants of difference. Phenotypes are defined as a gene’s effects relative to some alternative whereas the environment is defined as all parts of the world that are shared by the alternatives being compared. Environments choose among phenotypes and thereby choose among genes. By this process, successful gene sequences become stores of information about what works in the environment. The strategic gene is defined as a set of gene tokens that combines (...) ‘actor’ tokens responsible for an effect with ‘recipient’ tokens whose replication is thereby enhanced. This set of tokens can extend across the boundaries of individual organisms, or other levels of selection, as these are traditionally defined. Content Type Journal Article Pages 1-19 DOI 10.1007/s10539-012-9315-5 Authors DavidHaig, Department of Organismic and Evolutionary Biology, Harvard University, 26 Oxford Street, Cambridge, MA 02138, USA Journal Biology and Philosophy Online ISSN 1572-8404 Print ISSN 0169-3867. (shrink)
    Direct download(3 more)  
     
    Export citation  
     
    Bookmark   26 citations  
  38.  23
    Is Democracy Anti-intellectual? Tocqueville on the Life of the Mind in Modern Democracy.Haig Patapan -2024 -Journal of Social and Political Philosophy 3 (2):159-177.
    Democracy is admired for fostering deliberation, debate and innovation. Yet there is also the persistent suspicion that it is anti-intellectual. This article turns to one of the foremost theorists of modern democracy, Alexis de Tocqueville, to assess his contribution to the debate on democratic anti-intellectualism. It argues that Tocqueville denies democracy is anti-intellectual, yet he also claims democracy favours a distinctive intellectual life, informed theoretically by a Cartesian scepticism and practically by the dominance of a practical and commercial perspective in (...) the sciences, arts and literature. The article concludes by examining the technocratic implications of this form of intellectualism for democratic stability and legitimacy. (shrink)
    No categories
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark  
  39.  45
    The politics of modern honor.Haig Patapan -2018 -Contemporary Political Theory 17 (4):459-477.
    Modern honor appears to be distinguished by two contradictory impulses, a neglect or even disdain of honor, and an ambition to elevate and promote it as dignity, self-esteem, and recognition. The article argues that these tensions can be traced to a foundational difference regarding the political importance of the passion of honor, evident in the seminal and contending formulations by Machiavelli and Hobbes. In recovering and articulating the bases of these competing modern conceptions of honor and tracing the influence of (...) their divergent trajectories, the article seeks to show the importance of honor for understanding contemporary politics. (shrink)
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  40.  26
    Jun-Hyeok Kwak ed.Machiavelli in Northeast Asia.Haig Patapan -2023 -Journal of Social and Political Philosophy 2 (2):231-233.
    No categories
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark  
  41.  93
    Love and the Leviathan.Haig Patapan &Jeffrey Sikkenga -2008 -Political Theory 36 (6):803-826.
    Hobbes's understanding of love, and its significance for his political thought, has received insufficient attention. This essay contends that Hobbes has a consistent and comprehensive teaching on love that directly repudiates what he regards as the Platonic teaching on eros. In attacking the Platonic idea of eros, Hobbes undermines a pillar of classical political philosophy and articulates a significant aspect of his new understanding of the passions in terms of power, which is itself a critical part of his new political (...) science most famously presented in Leviathan. (shrink)
    Direct download(5 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  42.  187
    Weismann rules! OK? Epigenetics and the Lamarckian temptation.DavidHaig -2007 -Biology and Philosophy 22 (3):415-428.
    August Weismann rejected the inheritance of acquired characters on the grounds that changes to the soma cannot produce the kind of changes to the germ-plasm that would result in the altered character being transmitted to subsequent generations. His intended distinction, between germ-plasm and soma, was closer to the modern distinction between genotype and phenotype than to the modern distinction between germ cells and somatic cells. Recently, systems of epigenetic inheritance have been claimed to make possible the inheritance of acquired characters. (...) I argue that the sense in which these claims are true does not challenge fundamental tenets of neo-Darwinism. Epigenetic inheritance expands the range of options available to genes but evolutionary adaptation remains the product of natural selection of ‘random’ variation. (shrink)
    Direct download(4 more)  
     
    Export citation  
     
    Bookmark   39 citations  
  43.  79
    How to pursue the adaptationist program in psychology.Russil Durrant &Brian D.Haig -2001 -Philosophical Psychology 14 (4):357 – 380.
    In recent times evolutionary psychologists have offered adaptation explanations for a wide range of human psychological characteristics. Critics, however, have argued that such endeavors are problematic because the appropriate evidence required to demonstrate adaptation is unlikely to be forthcoming, therefore severely limiting the role of the adaptationist program in psychology. More specifically, doubts have been raised over both the methodology employed by evolutionary psychologists for studying adaptations and about the possibility of ever developing acceptably rigorous evolutionary explanations of human psychological (...) phenomena. We argue that by employing a wide range of methods for inferring adaptation and by adopting an inference to the best explanation strategy for evaluating adaptation explanations, these two doubts can be adequately addressed. We illustrate how this approach can be fruitfully employed in evaluating claims about the evolutionary origins of language, and conclude with a brief discussion of the future of evolutionary psychology. (shrink)
    Direct download(4 more)  
     
    Export citation  
     
    Bookmark   7 citations  
  44.  11
    Parenting in Public: Family Shelter and Public Assistance.DonnaHaig Friedman -2000 - Columbia University Press.
    When parents must rely on public assistance and family shelters to provide for their children's most basic needs, they lose autonomy. Within a system of public assistance that already stigmatizes and isolates its beneficiaries, their family lives become subject to public scrutiny and criticism. They are _parenting in public._ This book is an in-depth examination of the realities of life for parents and their children in family shelters. The author uses the Massachusetts family shelter system to explore the impact of (...) asset and deficit-oriented help-giving approaches as they are experienced by mothers and service providers. The format of the book is unique. Following each chapter are the "reflections" of a mother who has parented in a shelter, a front-line worker, and a shelter director. The author and contributors propose a "Power With" policy and practice framework that runs counter to the prevailing "Power Over" cultural policy trends. Contributors include Rosa Clark, Brenda Farrell, Deborah Gray, Michele Kahan, Margaret A. Leonard, Mary T. Lewis, Nancy Schwoyer, and Elizabeth Ward. (shrink)
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark  
  45.  46
    Al-Kindi's Epistle on the Finitude of the Universe.Nicholas Rescher,Haig Khatchadourian &Ya'qub Al-Kindi -1965 -Isis 56:426-433.
  46.  66
    Scientific problems and the conduct of research.Brian D.Haig -1987 -Educational Philosophy and Theory 19 (2):22–32.
  47.  46
    Genetic dissent and individual compromise.DavidHaig -2014 -Biology and Philosophy 29 (2):233-239.
    Organisms can be treated as optimizers when there is consensus among their genes about what is best to be done, but genomic consensus is often lacking, especially in interactions among kin because kin share some genes but not others. Grafen adopts a majoritarian perspective in which an individual’s interests are identified with the interests of the largest coreplicon of its genome, but genomic imprinting and recombination factionalize the genome so that no faction may predominate in some interactions among kin. Once (...) intragenomic conflicts are recognized, the individual organism can be conceptualized as an arbiter among competing interests within a collective. Organismal adaptation can be recognized without phenotypes being optimized. (shrink)
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark   7 citations  
  48.  23
    Concerted evolution of ribosomal DNA: Somatic peace amid germinal strife.DavidHaig -2021 -Bioessays 43 (12):2100179.
    Most eukaryotes possess many copies of rDNA. Organismal selection alone cannot maintain rRNA function because the effects of mutations in one rDNA are diluted by the presence of many other rDNAs. rRNA quality is maintained by processes that increase homogeneity of rRNA within, and heterogeneity among, germ cells thereby increasing the effectiveness of cellular selection on ribosomal function. A successful rDNA repeat will possess adaptations for spreading within tandem arrays by intranuclear selection. These adaptations reside in the non‐coding regions of (...) rDNA. Single‐copy genes are predicted to manage processes of intranuclear and cellular selection in the germline to maintain the quality of rRNA expressed in somatic cells of future generations. (shrink)
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  49.  50
    Intracellular evolution of mitochondrial DNA (mtDNA) and the tragedy of the cytoplasmic commons.DavidHaig -2016 -Bioessays 38 (6):549-555.
    Mitochondria exist in large numbers per cell. Therefore, the strength of natural selection on individual mtDNAs for their contribution to cellular fitness is weak whereas the strength of selection in favor of mtDNAs that increase their own replication without regard for cellular functions is strong. This problem has been solved for most mitochondrial genes by their transfer to the nucleus but a few critical genes remain encoded by mtDNA. Organisms manage the evolution of mtDNA to prevent mutational decay of essential (...) services mitochondria provide to their hosts. Bottlenecks of mitochondrial numbers in female germlines increase the homogeneity of mtDNAs within cells and allow intraorganismal selection to eliminate cells with low quality mitochondria. Mechanisms of intracellular “quality control” allow direct selection on the competence of individual mtDNAs. These processes maintain the integrity of mtDNAs within the germline but are inadequate to indefinitely maintain mitochondrial function in somatic cells. (shrink)
    Direct download(4 more)  
     
    Export citation  
     
    Bookmark   4 citations  
  50.  25
    Transposable elements: Self‐seekers of the germline, team‐players of the soma.DavidHaig -2016 -Bioessays 38 (11):1158-1166.
    The germ track is the cellular path by which genes are transmitted to future generations whereas somatic cells die with their body and do not leave direct descendants. Transposable elements (TEs) evolve to be silent in somatic cells but active in the germ track. Thus, the performance of most bodily functions by a sequestered soma reduces organismal costs of TEs. Flexible forms of gene regulation are permissible in the soma because of the self‐imposed silence of TEs, but strict licensing of (...) transcription and translation is maintained in the germ track to control proliferation of TEs. Delayed zygotic genome activation (ZGA) and maternally inherited germ granules are adaptations that enhance germ‐track security. Mammalian embryos exhibit very early ZGA associated with extensive mobilization of retroelements. This window of vulnerability to retrotransposition in early embryos is an indirect consequence of evolutionary conflicts within the mammalian genome over postzygotic maternal provisioning. (shrink)
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark   4 citations  
1 — 50 / 201
Export
Limit to items.
Filters





Configure languageshere.Sign in to use this feature.

Viewing options


Open Category Editor
Off-campus access
Using PhilPapers from home?

Create an account to enable off-campus access through your institution's proxy server or OpenAthens.


[8]ページ先頭

©2009-2025 Movatter.jp