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Results for 'Christine B. Weldon'

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  1.  16
    Challenges of coverage policy development for next-generation tumor sequencing panels: Experts and payers weigh in.Julia R. Trosman,Christine B.Weldon,R. Kate Kelley &Kathryn A. Phillips -unknown
    © JNCCN-Journal of the National Comprehensive Cancer Network.Background: Next-generation tumor sequencing panels, which include multiple established and novel targets across cancers, are emerging in oncology practice, but lack formal positive coverage by US payers. Lack of coverage may impact access and adoption. This study identified challenges of NGTS coverage by private payers.Methods: We conducted semi-structured interviews with 14 NGTS experts on potential NGTS benefits, and with 10 major payers, representing more than 125,000,000 enrollees, on NGTS coverage considerations. We used the (...) framework approach of qualitative research for study design and thematic analyses and simple frequencies to further describe findings.Results: All interviewed payers see potential NGTS benefits, but all noted challenges to formal coverage: 80% state that inherent features of NGTS do not fit the medical necessity definition required for coverage, 70% view NGTS as a bundle of targets versus comprehensive tumor characterization and may evaluate each target individually, and 70% express skepticism regarding new evidence methods proposed for NGTS. Fifty percent of payers expressed sufficient concerns about NGTS adoption and implementation that will preclude their ability to issue positive coverage policies.Conclusions: Payers perceive that NGTS holds significant promise but, in its current form, poses disruptive challenges to coverage policy frameworks. Proactive multidisciplinary efforts to define the direction for NGTS development, evidence generation, and incorporation into coverage policy are necessary to realize its promise and provide patient access. This study contributes to current literature, as possibly the first study to directly interview US payers on NGTS coverage and reimbursement. (shrink)
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  2.  15
    Le renouvellement de l'esprit par l'adage.Christine B. Beuermann -1985 -Bibliothèque d'Humanisme Et Renaissance 47 (2):343-355.
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  3.  16
    Cold intolerance after brachial plexus nerve injury.Christine B. Novak,Dimitri J. Anastakis,Dorcas E. Beaton,Susan E. Mackinnon &Joel Katz -2012 - In Zdravko Radman,The Hand. MIT Press. pp. 66-71.
  4.  4
    Empirical legal training in the US academy.Christine B. Harrington &Sally Engle Merry -2010 - In Peter Cane & Herbert M. Kritzer,The Oxford handbook of empirical legal research. New York: Oxford University Press.
    This article begins with discussing challenges encountered while managing the epistemology of legal modes of thinking and social science, and the limits of relying on discipline-based methodologies for the advancement of empirical legal scholarship. In then discusses two approaches to empirical legal training employed in New York. Through this, it seeks to demonstrate the strengths of collaborative research with illustrations of a cross-national collaboration. Empirical research on law is a multi-method phenomenon. Ideally, empirical legal training means that students need and (...) can further foster a background in a broad range of social science methods and in a set of methods that can use triangulation or juxtaposition to capture the factors that explain law as a social phenomenon. (shrink)
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  5.  27
    Empirical legal training in the US academy.Christine B. Harrington &Sally Engle Merry -2010 - In Peter Cane & Herbert M. Kritzer,The Oxford handbook of empirical legal research. New York: Oxford University Press.
    This article begins with discussing challenges encountered while managing the epistemology of legal modes of thinking and social science, and the limits of relying on discipline-based methodologies for the advancement of empirical legal scholarship. In then discusses two approaches to empirical legal training employed in New York. Through this, it seeks to demonstrate the strengths of collaborative research with illustrations of a cross-national collaboration. Empirical research on law is a multi-method phenomenon. Ideally, empirical legal training means that students need and (...) can further foster a background in a broad range of social science methods and in a set of methods that can use triangulation or juxtaposition to capture the factors that explain law as a social phenomenon. (shrink)
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  6.  47
    Max Seidel, Father and Son: Nicola and Giovanni Pisano. 2 vols. Munich: Hirmer Verlag, 2012. 1: pp. 468; 424 black-and-white figures. 2: pp. 521; 504 black-and-white plates. $185. ISBN: 9783777451015. [REVIEW]Christine B. Verzar -2014 -Speculum 89 (1):245-247.
  7.  22
    Practical Ethics: A Medical Student’s Ethical Case in Surgery Clerkship.Christine B. Kwak -2023 -Journal of Clinical Ethics 34 (3):282-284.
    One factor that impedes medical students from speaking up about ethical situations is the lack of sufficient knowledge and skills in conflict resolution. This may also affect students’ decision and timing to intervene. This article will provide practical ways to effectively and efficiently address the medical student’s ethical case presented in August A. Culbert et al.’s “Navigating Informed Consent and Patient Safety in Surgery: Lessons for Medical Students and Junior Trainees.”.
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  8. William Butler Yeats and the Nobel Prize.Christine B. Hoffman -1968 -Pacific Philosophical Quarterly 49 (1):103.
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  9. Linda Seidel, Legends in Limestone: Lazarus, Gislebertus, and the Cathedral of Autun. Chicago and London: University of Chicago Press, 1999. Pp. xvi, 220; black-and-white frontispiece and 95 black-and-white figures. $32.50. [REVIEW]Christine B. Verzar -2001 -Speculum 76 (3):792-793.
     
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  10.  28
    Defeat, Entrapment, and Positive Future Thinking: Examining Key Theoretical Predictors of Suicidal Ideation Among Adolescents.Olivia H. Pollak,Eleonora M. Guzmán,Ki Eun Shin &Christine B. Cha -2021 -Frontiers in Psychology 12.
    Adult-based suicide theories have determined much of what we know about suicidal ideation. Here, we investigate the extent to which elements of theIntegrated Motivational-Volitional(IMV) model generalize to adolescence, a period when rates of suicidal ideation increase dramatically. In a sample of community-based adolescents (n= 74), we tested whether defeat and entrapment related to suicidal ideation, and whether poor positive future thinking abilities exacerbated this association. Consistent with the IMV model, we found that defeat/entrapment was associated specifically with history of suicidal (...) ideation, and not with history of suicide attempt. Defeat/entrapment was related to baseline suicidal ideation severity above and beyond depressive symptoms. While defeat/entrapment predicted future suicidal ideation controlling for history of ideation, it did not do so controlling for depressive symptoms. Counter to the IMV model, we initially found that the association between defeat/entrapment and suicidal ideation was strongest among adolescents withgreaterpositive future thinking abilities. This was driven by the tendency to imagine more positive future events, particularly those that are less realistic and achievable. These findings call for a more nuanced understanding of defeat/entrapment and positive future thinking among adolescents, particularly in how they interact to predict recurrent suicidal ideation. (shrink)
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  11.  44
    The evolutionary history of the first three enzymes in pyrimidine biosynthesis.Jeffrey N. Davidson,Kuey C. Chen,Robert S. Jamison,Lisa A. Musmanno &Christine B. Kern -1993 -Bioessays 15 (3):157-164.
    Some metabolic pathways are nearly ubiquitous among organisms: the genes encoding the enzymes for such pathways must therefore be ancient and essential. De novo pyrimidine biosynthesis is an example of one such metabolic pathway. In animals a single protein called CADAbbreviations: CAD, trifunctional protein catalyzing the first three steps of de novo pyrimidine biosynthesis in higher eukaryotes; CPS, carbamyl phosphate synthetase domain; CPSase, carbamyl phosphate synthetase activity; ATC, aspartate transcarbamylase domain; ATCase, aspartate transcarbamylase activity; DHO, dihydroorotase domain; DHOase, dihydroorotase activity; (...) GLN, glutaminase subdomain or subunit of carbamyl phosphate synthetase, GL Nase, glutaminase activity; SYN, synthetase subdomain or subunit of carbamyl phosphate synthetase; SYNase, synthetase activity. carries the first three steps of this pathway. The same three enzymes in prokaryotes are associated with separate proteins. The CAD gene appears to have evolved through a process of gene duplication and DNA rearrangement, leading to an in‐frame gene fusion encoding a chimeric protein. A driving force for the creation of eukaryotic genes encoding multienzymatic proteins such as CAD may be the advantage of coordinate expression of enzymes catalyzing steps in a biosynthetic pathway. The analogous structure in bacteria is the operon. Differences in the translational mechanisms of eukaryotes and prokaryotes may have dictated the different strategies used by organisms to evolve coordinately regulated genes. (shrink)
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  12.  27
    Explaining dissociations between implicit and explicit measures of retention: A processing account.Mary SusanWeldon,H. L. Roediger &B. H. Challis -1989 - In Henry L. I. Roediger & Fergus I. M. Craik,Varieties of Memory and Consciousness: Essays in Honor of Endel Tulving. Lawrence Erlbaum.
  13. Brigitte cambon de lavalette, Charles tijus.Christine Leproux,Olivier Bauer,J. Gregory Trafton,Susan B. Trickett,Lorenzo Magnani &Matteo Piazza -2005 -Foundations of Science 10:457-458.
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  14.  70
    Ethical and Social Aspects of Neurorobotics.Christine Aicardi,Simisola Akintoye,B. Tyr Fothergill,Manuel Guerrero,Gudrun Klinker,William Knight,Lars Klüver,Yannick Morel,Fabrice O. Morin,Bernd Carsten Stahl &Inga Ulnicane -2020 -Science and Engineering Ethics 26 (5):2533-2546.
    The interdisciplinary field of neurorobotics looks to neuroscience to overcome the limitations of modern robotics technology, to robotics to advance our understanding of the neural system’s inner workings, and to information technology to develop tools that support those complementary endeavours. The development of these technologies is still at an early stage, which makes them an ideal candidate for proactive and anticipatory ethical reflection. This article explains the current state of neurorobotics development within the Human Brain Project, originating from a close (...) collaboration between the scientific and technical experts who drive neurorobotics innovation, and the humanities and social sciences scholars who provide contextualising and reflective capabilities. This article discusses some of the ethical issues which can reasonably be expected. On this basis, the article explores possible gaps identified within this collaborative, ethical reflection that calls for attention to ensure that the development of neurorobotics is ethically sound and socially acceptable and desirable. (shrink)
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  15.  56
    Disruption of Foveal Space Impairs Discrimination of Peripheral Objects.Kimberly B.Weldon,Anina N. Rich,Alexandra Woolgar &Mark A. Williams -2016 -Frontiers in Psychology 7.
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  16.  25
    Corrigendum: Yoga, Meditation and Mind-Body Health: Increased BDNF, Cortisol Awakening Response, and Altered Inflammatory Marker Expression After a 3-Month Yoga and Meditation Retreat.B. Rael Cahn,Matthew S. Goodman,Christine T. Peterson,Raj Maturi &Paul J. Mills -2022 -Frontiers in Human Neuroscience 16.
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  17.  19
    Visual dimensional dominance and haptic form recognition.Christine Micallef &Richard B. May -1976 -Bulletin of the Psychonomic Society 7 (1):21-24.
  18.  43
    Yoga, Meditation and Mind-Body Health: Increased BDNF, Cortisol Awakening Response, and Altered Inflammatory Marker Expression after a 3-Month Yoga and Meditation Retreat.B. Rael Cahn,Matthew S. Goodman,Christine T. Peterson,Raj Maturi &Paul J. Mills -2017 -Frontiers in Human Neuroscience 11:229690.
    Thirty-eight individuals (mean age: 34.8 years old) participating in a 3-month yoga and meditation retreat were assessed before and after the intervention for psychometric measures, brain derived neurotrophic factor (BDNF), circadian salivary cortisol levels, and pro- and anti-inflammatory cytokines. Participation in the retreat was found to be associated with decreases in self-reported anxiety and depression as well as increases in mindfulness. As hypothesized, increases in the plasma levels of BDNF and increases in the magnitude of the cortisol awakening response (CAR) (...) were also observed. The normalized change in BDNF levels was inversely correlated with BSI-18 anxiety scores at both the pre-retreat (r = 0.40, p< 0.05) and post-retreat (r = 0.52, p< 0.005) such that those with greater anxiety scores tended to exhibit smaller pre- to post-retreat increases in plasma BDNF levels. In line with a hypothesized decrease in inflammatory processes resulting from the yoga and meditation practices, we found that the plasma level of the anti-inflammatory cytokine Interleukin-10 was increased and the pro-inflammatory cytokine Interleukin-12 was reduced after the retreat. Contrary to our initial hypotheses, plasma levels of other pro-inflammatory cytokines, including Interferon Gamma (IFN-γ), Tumor Necrosis Factor (TNF-α), Interleukin-1β (IL-1β), Interleukin-6 (IL-6), and Interleukin-8 (IL-8) were increased after the retreat. Given evidence from previous studies of the positive effects of meditative practices on mental fitness, autonomic homeostasis and inflammatory status, we hypothesize that these findings are related to the meditative practices throughout the retreat; however, some of the observed changes may also be related to other aspects of the retreat such as physical exercise-related components of the yoga practice and diet. We hypothesize that the patterns of change observed here reflect mind-body integration and well-being. The increased BDNF levels observed is a potential mediator between meditative practices and brain health, the increased CAR is likely a reflection of increased dynamic physiological arousal, and the relationship of the dual enhancement of pro- and anti-inflammatory cytokine changes to healthy immunologic functioning is discussed. (shrink)
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  19.  273
    New books. [REVIEW]T. D.Weldon,P. Nowell-Smith,A. H. Armstrong,B. A. Farrell,H. D. Lewis,P. L. Heath,Vincent Turner,Karl Britton &D. J. M.`Cracken -1948 -Mind 57 (227):382-398.
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  20.  13
    Contemporary approaches to protein structure classification.Mark B. Swindells,Christine A. Orengo,David T. Jones,E. Gail Hutchinson &Janet M. Thornton -1998 -Bioessays 20 (11):884-891.
  21.  15
    Im Stromgebiet des Irrawaddy, Birma und seine Frauenwelt.B. Laufer,Lucian Scherman &Christine Scherman -1925 -Journal of the American Oriental Society 45:189.
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  22.  33
    Embedded Ethics in Practice: A Toolbox for Integrating the Analysis of Ethical and Social Issues into Healthcare AI Research.Theresa Willem,Marie-Christine Fritzsche,Bettina M. Zimmermann,Anna Sierawska,Svenja Breuer,Maximilian Braun,Anja K. Ruess,Marieke Bak,Franziska B. Schönweitz,Lukas J. Meier,Amelia Fiske,Daniel Tigard,Ruth Müller,Stuart McLennan &Alena Buyx -2025 -Science and Engineering Ethics 31 (1):1-22.
    Integrating artificial intelligence (AI) into critical domains such as healthcare holds immense promise. Nevertheless, significant challenges must be addressed to avoid harm, promote the well-being of individuals and societies, and ensure ethically sound and socially just technology development. Innovative approaches like Embedded Ethics, which refers to integrating ethics and social science into technology development based on interdisciplinary collaboration, are emerging to address issues of bias, transparency, misrepresentation, and more. This paper aims to develop this approach further to enable future projects (...) to effectively deploy it. Based on the practical experience of using ethics and social science methodology in interdisciplinary AI-related healthcare consortia, this paper presents several methods that have proven helpful for embedding ethical and social science analysis and inquiry. They include (1) stakeholder analyses, (2) literature reviews, (3) ethnographic approaches, (4) peer-to-peer interviews, (5) focus groups, (6) interviews with affected groups and external stakeholders, (7) bias analyses, (8) workshops, and (9) interdisciplinary results dissemination. We believe that applying Embedded Ethics offers a pathway to stimulate reflexivity, proactively anticipate social and ethical concerns, and foster interdisciplinary inquiry into such concerns at every stage of technology development. This approach can help shape responsible, inclusive, and ethically aware technology innovation in healthcare and beyond. (shrink)
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  23.  62
    Lack of ethics or lack of knowledge? European upper secondary students’ doubts and misconceptions about integrity issues.Thomas Bøker Lund,Peter Sandøe,P. J. Wall,Vojko Strahovnik,Céline Schöpfer,Rita Santos,Júlio Borlido Santos,Una Quinn,Margarita Poškutė,I. Anna S. Olsson,Søren Saxmose Nielsen,Marcus Tang Merit,Linda Hogan,Roman Globokar,Eugenijus Gefenas,Christine Clavien,Mateja Centa,Mads Paludan Goddiksen &Mikkel Willum Johansen -2022 -International Journal for Educational Integrity 18 (1).
    Plagiarism and other transgressions of the norms of academic integrity appear to be a persistent problem among upper secondary students. Numerous surveys have revealed high levels of infringement of what appear to be clearly stated rules. Less attention has been given to students’ understanding of academic integrity, and to the potential misconceptions and false beliefs that may make it difficult for them to comply with existing rules and handle complex real-life situations.In this paper we report findings from a survey of (...) European upper secondary students’ views on issues relating to academic integrity. We relate these findings to the students’ training about academic integrity, self-reported level of questionable behavior and country of study.A total of 1654 students at 51 institutions located in 6 European countries participated in the study. The participants generally believed they had a good understanding of the rules applying to them and knew how to behave in compliance with norms of academic integrity. The results indicate, however, that often, in practice, this belief was mistaken. Many students had an inadequate understanding of core elements of academic integrity. They were uncertain about how to act, and they struggled in the handling of complex situations that require context-sensitive judgement. While some differences between countries were identified, they were modest and exhibited no clear pattern. Our results also suggest that reducing students’ level of uncertainty and, to a lesser degree, improving their level of knowledge could lead them to engage less in certain types of questionable behaviours. Surprisingly, the effect of academic training is modest and ambiguous. The study also confirms that perception of peer behaviour has the strongest association with student engagement in questionable behaviours. Thus, academic integrity at the upper secondary level cannot be explained simply in terms of individual ethics or knowledge. (shrink)
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  24.  11
    La phrase: énonciation et information.Haiim B. Rosén,Société de Linguistique de Paris,Laurent Danon-Boileau,Marie-Christine Hazaël-Massieux,Jack Feuillet,Irina Fougeron,Jean Perrot &Mary-Annick Morel -1994 - Paris: Klincksieck.
    Marcel Beaufils fut un pedagogue exceptionnel qui exerca une influence decisive sur l'evolution de l'esthetique musicale en France, a partir des annees 50. Or, parmi ses ouvrages, Musique du son, musique du verbe est tres certainement celui qui porte le plus fortement la marque de son activite d'enseignant au Conservatoire National Superieur de Musique de Paris ; cette mission, il semblait l'entendre davantage comme celle d'un declencheur d'idees, catalyseur, plutot que du transmetteur d'un savoir fige une fois pour toutes. Bouleversant (...) toute tentative de classification academique, toute certitude acquise, ce livre laisse des pointilles ; un grand souffle traverse son ecriture. N'en deplaise aux musicographes, il s'agit la d'un ouvrage de creation, qui nous rappelle que Marce Beaufils etait egalement un ecrivain qui savait manier le verbe a la fois en tant que dramaturge et en tant que poete. (shrink)
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  25. Correspondance.Immanuel Kant,Marie-Christine Challiol,Michèle Halimi,Valérie Séroussi,Nicolas Aumonier &Marc B. de Launay -1993 -Revue de Métaphysique et de Morale 98 (1):277-279.
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  26.  17
    Cancer Patient Experience of Uncertainty While Waiting for Genome Sequencing Results.Nicci Bartley,Christine E. Napier,Zoe Butt,Timothy E. Schlub,Megan C. Best,Barbara B. Biesecker,Mandy L. Ballinger &Phyllis Butow -2021 -Frontiers in Psychology 12.
    There is limited knowledge about cancer patients' experiences of uncertainty while waiting for genome sequencing results, and whether prolonged uncertainty contributes to psychological factors in this context. To investigate uncertainty in patients with a cancer of likely hereditary origin while waiting for genome sequencing results, we collected questionnaire and interview data at baseline, and at three and 12 months follow up. Participants had negative attitudes towards uncertainty at baseline, and low levels of uncertainty at three and 12 months. Uncertainty about (...) genome sequencing did not change significantly over time [t = 0.660, p = 0.510]. Greater perceived susceptibility for cancer [r = 0.14, p< 0.01], fear of cancer recurrence [r = 0.19, p< 0.01], perceived importance of genome sequencing [r = 0.24, p< 0.01], intention to change behavior if a gene variant indicating risk is found [r = 0.29, p< 0.01], perceived ability to cope with results [r = 0.36, p< 0.01], and satisfaction with decision to have genome sequencing [r = 0.52, p< 0.01] were significantly correlated with negative attitudes towards uncertainty at baseline. Multiple primary cancer diagnoses [B = −2.364 [−4.238, −0.491], p = 0.014], lower perceived ability to cope with results [B = −0.1.881 [−3.403, −0.359], p = 0.016] at baseline, greater anxiety about genome sequencing [B = 0.347 [0.148, 0.546], p = 0.0012] at 3 months, and greater perceived uncertainty about genome sequencing [B = 0.494 [0.267, 0.721] p = 0.000] at 3 months significantly predicted greater perceived uncertainty about genome sequencing at 12 months. Greater perceived uncertainty about genome sequencing at 3 months significantly predicted greater anxiety about genome sequencing at 12 months [B = 0.291 [0.072, 0.509], p = 0.009]. Semi-structured interviews revealed that while participants were motivated to pursue genome sequencing as a strategy to reduce their illness and risk uncertainty, genome sequencing generated additional practical, scientific and personal uncertainties. Some uncertainties were consistently discussed over the 12 months, while others emerged over time. Similarly, some uncertainty coping strategies were consistent over time, while others emerged while patients waited for their genome sequencing results. This study demonstrates the complexity of uncertainty generated by genome sequencing for cancer patients and provides further support for the inter-relationship between uncertainty and anxiety. Helping patients manage their uncertainty may ameliorate psychological morbidity. (shrink)
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  27.  49
    Book Reviews Section 4.E. Paul Torrance,John Walton,Calvin O. Dyer,Virgil S. Ward,Weldon Beckner,Manouchehr Pedram,William M. Alexander,Herman J. Peters,James B. Macdonald,Samuel E. Kellams,Walter L. Hodges,Gary R. Mckenzie,Robert E. Jewett,Doris A. Trojcak,H. Parker Blount,George I. Brown,Lucile Lindberg,James C. Baughman,Patricia H. Dahl,S. Jay Samuels &Christopher J. Lucas -1972 -Educational Studies 3 (4):239-255.
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  28.  44
    Neutral but not in the middle: cross-cultural comparisons of negative bias of “neutral” emotional stimuli.Jini Tae,Ye-eun Nam,Yoonhyoung Lee,Rebecca B.Weldon &Myeong-Ho Sohn -2020 -Cognition and Emotion 34 (6):1171-1182.
    Previous studies have shown that the perception of neutral emotion stimuli can be negative rather than absolutely neutral. In the current study, we examined the negative bias of both neutral faces...
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  29.  50
    Corporate Social Responsibility, Ethical Leadership, and Trust Propensity: A Multi-Experience Model of Perceived Ethical Climate.S. Duane Hansen,Benjamin B. Dunford,Bradley J. Alge &Christine L. Jackson -2016 -Journal of Business Ethics 137 (4):649-662.
    Existing research on the formation of employee ethical climate perceptions focuses mainly on organization characteristics as antecedents, and although other constructs have been considered, these constructs have typically been studied in isolation. Thus, our understanding of the context in which ethical climate perceptions develop is incomplete. To address this limitation, we build upon the work of Rupp to develop and test a multi-experience model of ethical climate which links aspects of the corporate social responsibility, ethics, justice, and trust literatures and (...) helps to explain how employees’ ethical climate perceptions form. We argue that in forming ethical climate perceptions, employees consider the actions or characteristics of a complex web of actors. Specifically, we propose that employees look outward at how communities are impacted by their organization’s actions, upward to make inferences about the ethicality of leaders in their organizations, and inward at their own propensity to trust others as they form their perceptions. Using a multiple-wave field study conducted at a privately held US corporation, we find substantial evidence in support of our model. (shrink)
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  30.  4
    Transforming knowledge systems for life on Earth: Visions of future systems and how to get there.Ioan Fazey,Niko Schäpke,Guido Caniglia,Anthony Hodgson,Ian Kendrick,Christopher Lyon,Glenn Page,James Patterson,Chris Riedy,Tim Strasser,Stephan Verveen,David Adams,Bruce Goldstein,Matthias Klaes,Graham Leicester,Alison Linyard,Adrienne McCurdy,Paul Ryan,Bill Sharpe,Giorgia Silvestri,Ali Yansyah Abdurrahim,David Abson,Olufemi Samson Adetunji,Paulina Aldunce,Carlos Alvarez-Pereira,Jennifer Marie Amparo,Helene Amundsen,Lakin Anderson,Lotta Andersson,Michael Asquith,Karoline Augenstein,Jack Barrie,David Bent,Julia Bentz,Arvid Bergsten,Carol Berzonsky,Olivia Bina,Kirsty Blackstock,Joanna Boehnert,Hilary Bradbury,Christine Brand,Jessica Böhme Sangmeister),Marianne Mille Bøjer,Esther Carmen,Lakshmi Charli-Joseph,Sarah Choudhury,Supot Chunhachoti-Ananta,Jessica Cockburn,John Colvin,Irena L. C. Connon,Rosalind Cornforth,Robin S. Cox,Nicholas Cradock-Henry,Laura Cramer,Almendra Cremaschi,Halvor Dannevig,Catherine T. Day &Cathel Hutchison -unknown
    Formalised knowledge systems, including universities and research institutes, are important for contemporary societies. They are, however, also arguably failing humanity when their impact is measured against the level of progress being made in stimulating the societal changes needed to address challenges like climate change. In this research we used a novel futures-oriented and participatory approach that asked what future envisioned knowledge systems might need to look like and how we might get there. Findings suggest that envisioned future systems will need (...) to be much more collaborative, open, diverse, egalitarian, and able to work with values and systemic issues. They will also need to go beyond producing knowledge about our world to generating wisdom about how to act within it. To get to envisioned systems we will need to rapidly scale methodological innovations, connect innovators, and creatively accelerate learning about working with intractable challenges. We will also need to create new funding schemes, a global knowledge commons, and challenge deeply held assumptions. To genuinely be a creative force in supporting longevity of human and non-human life on our planet, the shift in knowledge systems will probably need to be at the scale of the enlightenment and speed of the scientific and technological revolution accompanying the second World War. This will require bold and strategic action from governments, scientists, civic society and sustained transformational intent. (shrink)
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  31.  200
    A Twenty-First Century Assessment of Values Across the Global Workforce.David A. Ralston,Carolyn P. Egri,Emmanuelle Reynaud,Narasimhan Srinivasan,Olivier Furrer,David Brock,Ruth Alas,Florian Wangenheim,Fidel León Darder,Christine Kuo,Vojko Potocan,Audra I. Mockaitis,Erna Szabo,Jaime Ruiz Gutiérrez,Andre Pekerti,Arif Butt,Ian Palmer,Irina Naoumova,Tomasz Lenartowicz,Arunas Starkus,Vu Thanh Hung,Tevfik Dalgic,Mario Molteni,María Teresa de la Garza Carranza,Isabelle Maignan,Francisco B. Castro,Yong-lin Moon,Jane Terpstra-Tong,Marina Dabic,Yongjuan Li,Wade Danis,Maria Kangasniemi,Mahfooz Ansari,Liesl Riddle,Laurie Milton,Philip Hallinger,Detelin Elenkov,Ilya Girson,Modesta Gelbuda,Prem Ramburuth,Tania Casado,Ana Maria Rossi,Malika Richards,Cheryl Van Deusen,Ping-Ping Fu,Paulina Man Kei Wan,Moureen Tang,Chay-Hoon Lee,Ho-Beng Chia,Yongquin Fan &Alan Wallace -2011 -Journal of Business Ethics 104 (1):1-31.
    This article provides current Schwartz Values Survey (SVS) data from samples of business managers and professionals across 50 societies that are culturally and socioeconomically diverse. We report the society scores for SVS values dimensions for both individual- and societal-level analyses. At the individual-level, we report on the ten circumplex values sub-dimensions and two sets of values dimensions (collectivism and individualism; openness to change, conservation, self-enhancement, and self-transcendence). At the societal-level, we report on the values dimensions of embeddedness, hierarchy, mastery, affective (...) autonomy, intellectual autonomy, egalitarianism, and harmony. For each society, we report the Cronbach’s α statistics for each values dimension scale to assess their internal consistency (reliability) as well as report interrater agreement (IRA) analyses to assess the acceptability of using aggregated individual level values scores to represent country values. We also examined whether societal development level is related to systematic variation in the measurement and importance of values. Thus, the contributions of our evaluation of the SVS values dimensions are two-fold. First, we identify the SVS dimensions that have cross-culturally internally reliable structures and within-society agreement for business professionals. Second, we report the society cultural values scores developed from the twenty-first century data that can be used as macro-level predictors in multilevel and single-level international business research. (shrink)
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  32.  70
    The Woman Who Cried Pain: Do Sex-Based Disparities Still Exist in the Experience and Treatment of Pain?Diane E. Hoffmann,Roger B. Fillingim &Christin Veasley -2022 -Journal of Law, Medicine and Ethics 50 (3):519-541.
    Over twenty years have passed since JLME published “The Girl Who Cried Pain: A Bias Against Women in the Treatment of Pain.” This article revisits the conclusions drawn in that piece and explores what we have learned in the last two decades regarding the experience of men and women who have chronic pain and whether women continue to be treated less aggressively for their pain than men.
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  33.  138
    Transforming knowledge systems for life on Earth: Visions of future systems and how to get there.Ioan Fazey,Niko Schäpke,Guido Caniglia,Anthony Hodgson,Ian Kendrick,Christopher Lyon,Glenn Page,James Patterson,Chris Riedy,Tim Strasser,Stephan Verveen,David Adams,Bruce Goldstein,Matthias Klaes,Graham Leicester,Alison Linyard,Adrienne McCurdy,Paul Ryan,Bill Sharpe,Giorgia Silvestri,Ali Yansyah Abdurrahim,David Abson,Olufemi Samson Adetunji,Paulina Aldunce,Carlos Alvarez-Pereira,Jennifer Marie Amparo,Helene Amundsen,Lakin Anderson,Lotta Andersson,Michael Asquith,Karoline Augenstein,Jack Barrie,David Bent,Julia Bentz,Arvid Bergsten,Carol Berzonsky,Olivia Bina,Kirsty Blackstock,Joanna Boehnert,Hilary Bradbury,Christine Brand,Jessica Böhme,Marianne Mille Bøjer,Esther Carmen,Lakshmi Charli-Joseph,Sarah Choudhury,Supot Chunhachoti-Ananta,Jessica Cockburn,John Colvin,Irena L. C. Connon &Rosalind Cornforth -2020 -Energy Research and Social Science 70.
    Formalised knowledge systems, including universities and research institutes, are important for contemporary societies. They are, however, also arguably failing humanity when their impact is measured against the level of progress being made in stimulating the societal changes needed to address challenges like climate change. In this research we used a novel futures-oriented and participatory approach that asked what future envisioned knowledge systems might need to look like and how we might get there. Findings suggest that envisioned future systems will need (...) to be much more collaborative, open, diverse, egalitarian, and able to work with values and systemic issues. They will also need to go beyond producing knowledge about our world to generating wisdom about how to act within it. To get to envisioned systems we will need to rapidly scale methodological innovations, connect innovators, and creatively accelerate learning about working with intractable challenges. We will also need to create new funding schemes, a global knowledge commons, and challenge deeply held assumptions. To genuinely be a creative force in supporting longevity of human and non-human life on our planet, the shift in knowledge systems will probably need to be at the scale of the enlightenment and speed of the scientific and technological revolution accompanying the second World War. This will require bold and strategic action from governments, scientists, civic society and sustained transformational intent. (shrink)
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  34.  118
    Moral Distress: A Growing Problem in the Health Professions?Connie M. Ulrich,Ann B. Hamric &Christine Grady -2010 -Hastings Center Report 40 (1):20-22.
  35.  23
    Everyday Clinical Ethics: Essential Skills and Educational Case Scenarios.Elaine C. Meyer,Giulia Lamiani,Melissa Uveges,Renee McLeod-Sordjan,Christine Mitchell,Robert D. Truog,Jonathan M. Marron,Kerri O. Kennedy,Marilyn Ritholz,Stowe Locke Teti &Aimee B. Milliken -forthcoming -HEC Forum:1-23.
    Bioethics conjures images of dramatic healthcare challenges, yet everyday clinical ethics issues unfold regularly. Without sufficient ethical awareness and a relevant working skillset, clinicians can feel ill-equipped to respond to the ethical dimensions of everyday care. Bioethicists were interviewed to identify the essential skills associated with everyday clinical ethics and to identify educational case scenarios to illustrate everyday clinical ethics. Individual, semi-structured interviews were conducted with a convenience sample of bioethicists. Bioethicists were asked: (1) What are the essential skills required (...) for everyday clinical ethics? And (2) What are potential educational case scenarios to illustrate and teach everyday clinical ethics? Participant interviews were analyzed using qualitative content analysis. Twenty-five (25) bioethicists completed interviews (64% female; mean 14.76 years bioethics experience; 80% white). Five categories of general skills and three categories of ethics-specific skills essential for everyday clinical ethics were identified. General skills included: (1) Awareness of Core Values and Self-Reflective Capacity; (2) Perspective-Taking and Empathic Presence; (3) Communication and Relational Skills; (4) Cultural Humility and Respect; and (5) Organizational Understanding and Know-How. Ethics-specific skills included: (1) Ethical Awareness; (2) Ethical Knowledge and Literacy; and (3) Ethical Analysis and Interaction. Collectively, these skills comprise a Toolbox of Everyday Clinical Ethics Skills. Educational case scenarios were identified to promote everyday ethics. Bioethicists identified skills essential to everyday clinical ethics. Educational case scenarios were identified for the purpose of promoting proficiency in this domain. Future research could explore the impact of integrating educational case scenarios on clinicians’ ethical competencies. (shrink)
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  36.  216
    New books. [REVIEW]C. D. Broad,Richard Robinson,H. B. Acton,George E. Hughes,T. D.Weldon,Mario M. Rossi,A. C. Ewing,C. J. Holloway,J. P. Corbett,C. W. K. Mundle,W. B. Gallie,W. Mays,A. H. Armstrong,C. K. Grant &I. M. Cromble -1949 -Mind 58 (229):101-130.
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  37.  55
    Getting under the Skin: Report from the International Psoriasis Council Workshop on the Role of Stress in Psoriasis.Julia Schwartz,Andrea W. M. Evers,Christine Bundy &Alexandra B. Kimball -2016 -Frontiers in Psychology 7.
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  38.  25
    A, B, C as linear as 1, 2, 3: Numerical and non-numerical representation in adults.PodwysockiChristine,Paul Jacob &Forte Jason -2015 -Frontiers in Human Neuroscience 9.
  39.  39
    Grey zones and good practice: A European survey of academic integrity among undergraduate students.Mads Paludan Goddiksen,Mikkel Willum Johansen,Anna Catharina Armond,Mateja Centa,Christine Clavien,Eugenijus Gefenas,Roman Globokar,Linda Hogan,Nóra Kovács,Marcus Tang Merit,I. Anna S. Olsson,Margarita Poškutė,Una Quinn,Júlio Borlido Santos,Rita Santos,Céline Schöpfer,Vojko Strahovnik,Orsolya Varga,P. J. Wall,Peter Sandøe &Thomas Bøker Lund -2024 -Ethics and Behavior 34 (3):199-217.
    Good academic practice is more than the avoidance of clear-cut cheating. It also involves navigation of the gray zones between cheating and good practice. The existing literature has left students’ understanding of gray zone practices largely unexplored. To begin filling in this gap, we present results from a questionnaire study involving N = 1639 undergraduate students from seven European countries representing all major disciplines. We show that large numbers of these students are unable to identify gray area issues and lack (...) sensitivity to the context dependence of these. We also show that a considerable proportion of students have a poor understanding of concepts like plagiarism and falsification, not only in gray zone scenarios, but also in cases of relatively clear-cut cheating. Our results are similar across the faculties and countries of study, and even for students who have attended academic integrity training. We discuss the implications of this for academic integrity training. (shrink)
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  40.  164
    Altruism across disciplines: one word, multiple meanings.Christine Clavien &Michel Chapuisat -2013 -Biology and Philosophy 28 (1):125-140.
    Altruism is a deep and complex phenomenon that is analysed by scholars of various disciplines, including psychology, philosophy, biology, evolutionary anthropology and experimental economics. Much confusion arises in current literature because the term altruism covers variable concepts and processes across disciplines. Here we investigate the sense given to altruism when used in different fields and argumentative contexts. We argue that four distinct but related concepts need to be distinguished: (a) psychological altruism , the genuine motivation to improve others’ interests and (...) welfare; (b) reproductive altruism , which involves increasing others’ chances of survival and reproduction at the actor’s expense; (c) behavioural altruism , which involves bearing some cost in the interest of others; and (d) preference altruism , which is a preference for others’ interests. We show how this conceptual clarification permits the identification of overstated claims that stem from an imprecise use of terminology. Distinguishing these four types of altruism will help to solve rhetorical conflicts that currently undermine the interdisciplinary debate about human altruism. (shrink)
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  41. Cross-species transcriptomic analysis elucidates constitutive aryl hydrocarbon receptor activity.Ren X. Sun,Lauren C. Chong,Trent T. Simmons,Kathleen E. Houlahan,Stephenie D. Prokopec,John D. Watson,Ivy D. Moffat,Sanna Lensu,Jere Lindén,Christine P'ng,Allan B. Okey,Raimo Pohjanvirta &Paul C. Boutros -unknown
    Background. Research on the aryl hydrocarbon receptor (AHR) has largely focused on variations in toxic outcomes resulting from its activation by halogenated aromatic hydrocarbons. But the AHR also plays key roles in regulating pathways critical for development, and after decades of research the mechanisms underlying physiological regulation by the AHR remain poorly characterized. Previous studies identified several core genes that respond to xenobiotic AHR ligands across a broad range of species and tissues. However, only limited inferences have been made regarding (...) its role in regulating constitutive gene activity, i.e. in the absence of exogenous ligands. To address this, we profiled transcriptomic variations between AHR-active and AHR-less-active animals in the absence of an exogenous agonist across five tissues, three of which came from rats (hypothalamus, white adipose and liver) and two of which came from mice (kidney and liver). Because AHR status alone has been shown sufficient to alter transcriptomic responses, we reason that by contrasting profiles amongst AHR-variant animals, we may elucidate effects of the AHR on constitutive mRNA abundances. Results. We found significantly more overlap in constitutive mRNA abundances amongst tissues within the same species than from tissues between species and identified 13 genes (Agt, Car3, Creg1, Ctsc, E2f6, Enpp1, Gatm, Gstm4, Kcnj8, Me1, Pdk1, Slc35a3, and Sqrdl) that are affected by AHR-status in four of five tissues. One gene, Creg1, was significantly up-regulated in all AHR-less-active animals. We also find greater overlap between tissues at the pathway level than at the gene level, suggesting coherency to the AHR signalling response within these processes. Analysis of regulatory motifs suggests that the AHR mostly mediates transcriptional regulation via direct binding to response elements. Conclusions. These findings, though preliminary, present a platform for further evaluating the role of the AHR in regulation of constitutive mRNA levels and physiologic function. (shrink)
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  42.  37
    Neural Processing of Facial Identity and Emotion in Infants at High-Risk for Autism Spectrum Disorders.Sharon E. Fox,Jennifer B. Wagner,Christine L. Shrock,Helen Tager-Flusberg &Charles A. Nelson -2013 -Frontiers in Human Neuroscience 7.
  43.  153
    Erratum to: A Twenty-First Century Assessment of Values Across the Global Workforce.David A. Ralston,Carolyn P. Egri,Emmanuelle Reynaud,Narasimhan Srinivasan,Olivier Furrer,David Brock,Ruth Alas,Florian Wangenheim,Fidel León Darder,Christine Kuo,Vojko Potocan,Audra I. Mockaitis,Erna Szabo,Jaime Ruiz Gutiérrez,Andre Pekerti,Arif Butt,Ian Palmer,Irina Naoumova,Tomasz Lenartowicz,Arunas Starkus,Vu Thanh Hung,Tevfik Dalgic,Mario Molteni,María Teresa de la Garza Carranza,Isabelle Maignan,Francisco B. Castro,Yong-lin Moon,Jane Terpstra-Tong,Marina Dabic,Yongjuan Li,Wade Danis,Maria Kangasniemi,Mahfooz Ansari,Liesl Riddle,Laurie Milton,Philip Hallinger,Detelin Elenkov,Ilya Girson,Modesta Gelbuda,Prem Ramburuth,Tania Casado,Ana Maria Rossi,Malika Richards,Cheryl Van Deusen,Ping-Ping Fu,Paulina Man Kei Wan,Moureen Tang,Chay-Hoon Lee,Ho-Beng Chia,Yongquin Fan &Alan Wallace -2011 -Journal of Business Ethics 104 (4):589-590.
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  44. Emotion, motivation and action: The case of fear.Christine Tappolet -2009 - In Peter Goldie,The Oxford Handbook of Philosophy of Emotion. New York: Oxford University Press. pp. 325-45.
    Consider a typical fear episode. You are strolling down a lonely mountain lane when suddenly a huge wolf leaps towards you. A number of different interconnected elements are involved in the fear you experience. First, there is the visual and auditory perception of the wild animal and its movements. In addition, it is likely that given what you see, you may implicitly and inarticulately appraise the situation as acutely threatening. Then, there are a number of physiological changes, involving a variety (...) of systems controlled by the autonomic nervous system. Your heart races, your breathing becomes strained and your start trembling. These changes are accompanied by an expression of fear on your face: your mouth opens and your eyes widen while you stare at the wolf. There is also a kind of experience that you undergo. You are likely to feel a sort of pang, something that might consist in the perception of the physiological changes you are going through. Moreover, a number of thoughts are likely to cross your mind. You might think that the wild beast is about to tear you into pieces and that you’ll never escape from this. In addition to this, your attention focuses on the wolf and its movement, as well as, possibly, ways of escaping or defending yourself. Last, but not least, your fear is likely to come with a motivation, such as an urge to run away or to strike back. Whatever the details of the story, it is clear that a typical emotion episode involves a number of different components. Roughly, these components are a) a sensory perception or more generally an informational component, b) a kind of appraisal, d) physiological changes, c) conscious feelings, d) cognitive and attentional processes, and e) an actiontendency or more generally a motivational component. One central question in the theory of emotion is which, if any, of these components, constitute the emotion.. (shrink)
     
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  45.  79
    Ethical Leadership: Assessing the Value of a Multifoci Social Exchange Perspective. [REVIEW]S. Duane Hansen,Bradley J. Alge,Michael E. Brown,Christine L. Jackson &Benjamin B. Dunford -2013 -Journal of Business Ethics 115 (3):435-449.
    In this study, we comprehensively examine the relationships between ethical leadership, social exchange, and employee commitment. We find that organizational and supervisory ethical leadership are positively related to employee commitment to the organization and supervisor, respectively. We also find that different types of social exchange relationships mediate these relationships. Our results suggest that the application of a multifoci social exchange perspective to the context of ethical leadership is indeed useful: As hypothesized, within-foci effects (e.g., the relationship between organizational ethical leadership (...) and commitment to the organization) are stronger than cross-foci effects (e.g., the relationship between supervisory ethical leadership and commitment to the organization). In addition, in contrast to the “trickle down” model of ethical leadership (Mayer et al. in Org Behav Hum Decis Process 108:1–13, 2009), our results suggest that organizational ethical leadership is both directly and indirectly related to employee outcomes. (shrink)
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  46. Burdon, RH (2003) The Suffering Gene: Environmental Threats to Our Health, Montreal: McGill-Queen's University Press. Cochrane, Willard W.(2003) The Curse of American Agricultural Abundance: A Sustainable Solution, Lincoln, NB: University of Nebraska Press. Dobson, Andrew (2003) Citizenship and the Environment, Oxford: Oxford University. [REVIEW]George A. Feldhamer,Bruce Carlyle Thompson,Joseph A. Chapman,Christine E. Gudorf,James E. Huchingson,M. Jacobs,B. Dinaham,Virginia D. Nazarea &M. Nestle -2004 -Ethics, Place and Environment 7 (1-2):120.
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  47. Christine Chwaszcza, Praktische Vernunft als vernunftige Praxis. Ein Grundriss. [REVIEW]B. Lahno -2005 -Philosophisches Jahrbuch 112 (1):252.
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  48.  168
    Erratum to: A Twenty-First Century Assessment of Values Across the Global Workforce.David A. Ralston,Carolyn P. Egri,Emmanuelle Reynaud,Narasimhan Srinivasan,Olivier Furrer,David Brock,Ruth Alas,Florian Wangenheim,Fidel Le?N. Darder,Christine Kuo,Vojko Potocan,Audra I. Mockaitis,Erna Szabo,Jaime Ruiz Guti?Rrez,Andre Pekerti,Arif Butt,Ian Palmer,Irina Naoumova,Tomasz Lenartowicz,Arunas Starkus,Vu Thanh Hung,Tevfik Dalgic,Mario Molteni,Mar?A. Teresa de la Garza Carranza,Isabelle Maignan,Francisco B. Castro,Yong-lin Moon,Jane Terpstra-Tong,Marina Dabic,Yongjuan Li,Wade Danis,Maria Kangasniemi,Mahfooz Ansari,Liesl Riddle,Laurie Milton,Philip Hallinger,Detelin Elenkov,Ilya Girson,Modesta Gelbuda,Prem Ramburuth,Tania Casado,Ana Maria Rossi,Malika Richards,Cheryl Van Deusen,Ping-Ping Fu,Paulina Man Kei Wan,Moureen Tang,Chay-Hoon Lee,Ho-Beng Chia,Yongquin Fan &Alan Wallace -2011 -Journal of Business Ethics 104 (4):589-590.
    This article provides current Schwartz Values Survey data from samples of business managers and professionals across 50 societies that are culturally and socioeconomically diverse. We report the society scores for SVS values dimensions for both individual- and societallevel analyses. At the individual- level, we report on the ten circumplex values sub- dimensions and two sets of values dimensions. At the societal- level, we report on the values dimensions of embeddedness, hierarchy, mastery, affective autonomy, intellectual autonomy, egalitarianism, and harmony. For each (...) society, we report the Cronbach' s? statistics for each values dimension scale to assess their internal consistency as well as report interrater agreement analyses to assess the acceptability of using aggregated individual level values scores to represent country span sp. (shrink)
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  49.  28
    René Descartes. Lettres sur la Morale. Correspondance avec la Princesse Elizabeth, Chanut et la ReineChristine[REVIEW]G. B. -1935 -Journal of Philosophy 32 (13):355-355.
  50.  156
    Positive emotions broaden the scope of attention and thought‐action repertoires.Barbara L. Fredrickson &Christine Branigan -2005 -Cognition and Emotion 19 (3):313-332.
    The broaden‐and‐build theory (CitationFredrickson, 1998, Citation2001) hypothesises that positive emotions broaden the scope of attention and thought‐action repertoires. Two experiments with 104 college students tested these hypotheses. In each, participants viewed a film that elicited (a) amusement, (b) contentment, (c) neutrality, (d) anger, or (e) anxiety. Scope of attention was assessed using a global‐local visual processing task (Experiment 1) and thought‐action repertoires were assessed using a Twenty Statements Test (Experiment 2). Compared to a neutral state, positive emotions broadened the scope (...) of attention in Experiment 1 and thought‐action repertoires in Experiment 2. In Experiment 2, negative emotions, relative to a neutral state, narrowed thought‐action repertoires. Implications for promoting emotional well‐being and physical health are discussed. (shrink)
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