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Levinas is in biografisch én in filosofisch opzicht met anti-judaïstische denkbeelden geconfronteerd. Over Christus heeft hij zich slechts sporadisch uitgelaten. Desondanks is zijn werk is te lezen als een ontzenuwing – zo men wil een ‘deconstructie’ – van een aantal klassiek christelijk dogmatische bepalingen, die voedsel gaven aan het antisemitisme. Hij denkt verder dan de traditionele onto-theologie en het daarbij behorende kosmologisch realisme of ethische moralisme. Hoe hij daarbij methodisch te werk gaat, wordt hieronder geschetst aan de hand van twee (...) samenhangende termen: schepping en plaatsvervanging. (shrink)

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In this article, the place and the nature of an ethical dialogue that develops within Christian healthcare institutions in Flanders, Belgium is examined. More specifically, the question is asked how Christian healthcare institutions should position themselves ethically in a context of a pluralistic society. The profile developed by Caritas Catholica Flanders must take seriously not only the external pluralistic context of our society and the internal pluralistic worldviews by personnel/employees and patients, but also the inherent inspiration of a Christian healthcare (...) institution. This article concludes with ten general orientations that could shape the ethical dialogue from a Christian inspiration in a pluralistic context. (shrink)

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The current medical approach to erectile dysfunction (ED) consists of physiological, psychological and social components. This paper proposes an additional framework for thinking about ED based on phenomenology, by focusing on the theory of sexual projection. This framework will be complementary to the current medical approach to ED. Our phenomenological analysis of ED provides philosophical depth and illuminates overlooked aspects in the study of ED. Mainly by appealing to Merleau-Ponty’s Phenomenology of Perception, we suggest considering an additional etiology of ED (...) in terms of a weakening of a function of sexual projection. We argue that sexual projection can be problematized through cognitive interferences, changes in the ‘intentional arc’, and modifications in the subject’s ‘body schema’. Our approach further highlights the importance of considering the ‘existential situation’ of patients with ED. We close by reflecting briefly on some of the implications of this phenomenological framework for diagnosis and treatment of ED. (shrink)

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Despite its uniform appearance, the cerebellar cortex is highly heterogeneous in terms of structure, genetics and physiology. Purkinje cells (PCs), the principal and sole output neurons of the cerebellar cortex, can be categorized into multiple populations that differentially express molecular markers and display distinctive physiological features. Such features include action potential rate, but also their propensity for synaptic and intrinsic plasticity. However, the precise molecular and genetic factors that correlate with the differential physiological properties of PCs remain elusive. In this (...) article, we provide a detailed overview of the cellular mechanisms that regulate PC activity and plasticity. We further perform a pathway analysis to highlight how molecular characteristics of specific PC populations may influence their physiology and plasticity mechanisms. (shrink)

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Is ChatGPT an author? Given its capacity to generate something that reads like human-written text in response to prompts, it might seem natural to ascribe authorship to ChatGPT. However, we argue that ChatGPT is not an author. ChatGPT fails to meet the criteria of authorship because it lacks the ability to perform illocutionary speech acts such as promising or asserting, lacks the fitting mental states like knowledge, belief, or intention, and cannot take responsibility for the texts it produces. Three perspectives (...) are compared: liberalism (which ascribes authorship to ChatGPT), conservatism (which denies ChatGPT's authorship for normative and metaphysical reasons), and moderatism (which treats ChatGPT as if it possesses authorship without committing to the existence of mental states like knowledge, belief, or intention). We conclude that conservatism provides a more nuanced understanding of authorship in AI than liberalism and moderatism, without denying the significant potential, influence, or utility of AI technologies such as ChatGPT. (shrink)

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Articulate language is a form of communication unique to humans. Over time, a spectrum of researchers has proposed various frameworks attempting to explain the evolutionary acquisition of this distinctive human attribute, some deploring the apparent lack of direct evidence elucidating the phenomenon, whilst others have pointed to the contributions of palaeoanthropology, the social brain hypothesis and the fact that even amongst contemporary humans, social group sizes reflect brain size. Theologians have traditionally ignored evolutionary insights as an explanatory paradigm for the (...) origin of humankind. However, an increasing number are, of late, contributing to a worldview of humanity which accommodates both the epistemological realities of evolutionary biology as well as insights from theology. This includes reviewing and assessing the origins of articulate language and the physiological attributes necessary for its development. It is in this sense that the evolution of language is relevant from a theological perspective. The association between mental capacity and articulate language, already noted by Darwin, is relevant in explaining the larger group sizes found amongst humans, as is the incipient role played by the evolution of laughter in triggering the neuroendocrine system promoting bonding, to the eventual development of articulate language. Our aim is to review a selection of contemporary perspectives on the evolution of language, amongst others, reasons for the ease with which young children acquire language competency, and whether we may be hardwired for language from birth. Further reading is suggested in the footnotes.Contribution: This article is part of a special collection reflecting on the evolutionary building blocks of our past, present and future. It is based on historical thought and contemporary research with regards to the evolutionary emergence of language. It fits well with the intersectional and trans-disciplinary nature of this collection and journal. (shrink)

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The House Sparrow (Passer domesticus), formerly a common bird species, has shown a rapid decline in Western Europe over recent decades. In The Netherlands, its decline is apparent from 1990 onwards. Many causes for this decline have been suggested that all decrease the vital rates, i.e. survival and reproduction, but their actual impact remains unknown. Although the House Sparrow has been dominant in The Netherlands, data on life history characteristics for this bird species are scarce: data on reproduction are non-existent, (...) and here we first present survival estimates based on live encounters and dead recoveries of marked individuals over the period 1976–2003, 14 years before and 14 years during the decline, reported to the Dutch Ringing Centre. We show that there is an indication that both juvenile and adult survival are lower during the period of decline. Secondly, to be able to analyse the relative impact of changes in the vital rates, we formulated a general matrix model based on a range of survival values between zero and one with a step size of 0.01 (both juvenile and adult yearly survival) and a range of realistic reproduction values (one, three or five fledglings per pair per year). With the matrix model, we calculated the finite rate of population change (λ) and applied elasticity analysis. To diagnose the cause of the decline in the Dutch House Sparrow, we parameterised the model with estimates of survival values before and during the decline and present the resulting λ. With the survival estimates from the declining period, λ< 1 only if reproduction is relatively low. We discuss this result within the light of available literature data on survival in the House Sparrow. Finally, we evaluate which of the suggested causes of population decline should be reversed to mitigate the decline and how this can be achieved. (shrink)

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In most decision-making situations, there is a plethora of information potentially available to people. Deciding what information to gather and what to ignore is no small feat. How do decision makers determine in what sequence to collect information and when to stop? In two experiments, we administered a version of the German cities task developed by Gigerenzer and Goldstein (1996), in which participants had to decide which of two cities had the larger population. Decision makers were not provided with the (...) names of the cities, but they were able to collect different kinds of cues for both response alternatives (e.g., “Does this city have a university?”) before making a decision. Our experiments differed in whether participants were free to determine the number of cues they examined. We demonstrate that a novel model, using hierarchical latent mixtures and Bayesian inference (Lee & Newell, 2011) provides a more complete description of the data from both experiments than simple conventional strategies, such as the take–the–best or the Weighted Additive heuristics. (shrink)

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The lostness measure, an implicit and unobtrusive measure originally designed for assessing the usability of hypertext systems, could be useful in Virtual Reality (VR) games where players need to find information to complete a task. VR locomotion systems with node-based movement mimic actions for exploration and browsing found in hypertext systems. For that reason, hypertext usability measures, such as “lostness” can be used to identify how disoriented a player is when completing tasks in an educational game by examining steps made (...) by the player. An evaluation of two different lostness measures, global and local lostness, based on two different types of tasks, is described in a VR educational game using 13 college students between 14 and 18 years old in a first study and extended using 12 extra participants in a second study. Multiple Linear Regression analyses showed, in both studies, that local lostness, and not global lostness, had a significant effect on a post-game knowledge test. Therefore, we argued that local lostness was able to predict how well-participants would perform on a post-game knowledge test indicating how well they learned from the game. In-game experience aspects (engagement, cognitive interest, and presence) were also evaluated and, interestingly, it was also found that participants learned less when they felt more present in the game. We believe these two measures relate to cognitive overload, which is known to have an adverse effect on learning. Further research should investigate the lostness measure for use in an online adaptive game system and design the game system in such a way that the risk of cognitive overload is minimized when learning, resulting in higher retention of information. (shrink)

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Introduction to the translation of “De vier religieuze grondthema’s in den ontwikkelingsgang van het wijsgeerig denken van het avondland” by Herman Dooyeweerd (1941), Philosophia Reformata 6 (4), pp. 161–179.

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Herman Dooyeweerd approached time in terms of order. By contrast, Dirk Vollenhoven saw time as continuous change and becoming. Hendrik Hart, in his article “Problems of Time: An Essay,” attempts to steer a middle course between Dooyeweerd and Vollenhoven. However, Hart did not sufficiently take into account that temporality is primarily continuous succession in duration and continuous duration in succession. Nor has he been able to come to terms with the root of cosmic time.

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Introduction to the translation of “De leer der analogie in de thomistische wijsbegeerte en in de wijsbegeerte der wetsidee” by Herman Dooyeweerd, Philosophia Reformata 7, pp. 47–57.

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The aim of this empirical study is to understand how bachelor students at universities of applied sciences (UAS) use their ethical compasses during internships. Semi-structured interviews were held with 36 fourth-year bachelor students across four UAS and three different programs in the Netherlands: Initial Teacher Education, Business Services, and Information and Communication Technology. To our knowledge, no studies appear to have investigated and compared students from multiple professional fields, nor identified the dynamics and the sequence of the strategies in the (...) decision-making process that students use when faced with ethical dilemmas during internships. We found that students’ ethical dilemmas stemmed from: mentors’ or managers’ behaviours/requests, colleagues’ behaviours, organisations’ morally questionable incentives, pupils’ home situations, and pupils’ behaviours/personal stories. The majority of students used multiple strategies and first investigated the ethical dilemmas they encountered and then avoided, intervened, delegated responsibilities, or adjusted to their environments. Students’ values played an important role in experiencing an ethical dilemma, however, these values were not always acted upon. We identified that rather students’ beliefs about having influence and/or ownership (or not), personal interest(s) and power relations influenced the way how they used their ethical compasses. Thus, instead of navigating on moral standards (of their profession), students reacted on beliefs which reflected the ways in which they constructed their internship contexts, social relationships and their own (and others) needs. As a result, half of the mentioned dilemmas were resolved in a prudent-strategic manner (e.g., by prioritising personal interests), instead of morally. This indicates that students did not always convert (moral) values into moral action and did not use their ethical compasses in the way UAS aspires. Finally, this study found that the ways in which students used their ethical compasses were strongly influenced by their environments. (shrink)

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Swords turning into ploughshares is not peace – Peace (שָׁלֹום) in Isaiah 40−44. ‘Swords being turned into ploughshares’ are often portrayed as being tantamount to peace. Peace though has got a more extensive meaning than only the absence of war. Whilst war and destruction is on the forefront in Isaiah 1–39, the opposite is true in Isaiah 40–66. The intention of this article is therefore to demonstrate the extensive meaning of peace (שָׁלֹום) as it unfolds as a motive in Isaiah (...) 40–66. Because of a lack of space, only the first three passages directly mentioning שָׁלֹום [peace] will be discussed. Even though this discussion will be incomplete, it will reveal that peace is not part of man’s normal state, that not everyone will experience peace and that there is a direct link between peace and the rule of God. (shrink)

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BackgroundInaccurate, false or incomplete research publications may mislead readers including researchers and decision-makers. It is therefore important that such problems are identified and rectified promptly. This usually involves collaboration between the research institutions and academic journals involved, but these interactions can be problematic.MethodsThese recommendations were developed following discussions at World Conferences on Research Integrity in 2013 and 2017, and at a specially convened 3-day workshop in 2016 involving participants from 7 countries with expertise in publication ethics and research integrity. The (...) recommendations aim to address issues surrounding cooperation and liaison between institutions and journals about possible and actual problems with the integrity of reported research arising before and after publication.ResultsThe main recommendations are that research institutions should: develop mechanisms for assessing the integrity of reported research that are distinct from processes to determine whether individual researchers have committed misconduct;release relevant sections of reports of research integrity or misconduct investigations to all journals that have published research that was investigated;take responsibility for research performed under their auspices regardless of whether the researcher still works at that institution or how long ago the work was done;work with funders to ensure essential research data is retained for at least 10 years.Journals should: respond to institutions about research integrity cases in a timely manner;have criteria for determining whether, and what type of, information and evidence relating to the integrity of research reports should be passed on to institutions;pass on research integrity concerns to institutions, regardless of whether they intend to accept the work for publication;retain peer review records for at least 10 years to enable the investigation of peer review manipulation or other inappropriate behaviour by authors or reviewers.ConclusionsVarious difficulties can prevent effective cooperation between academic journals and research institutions about research integrity concerns and hinder the correction of the research record if problems are discovered. While the issues and their solutions may vary across different settings, we encourage research institutions, journals and funders to consider how they might improve future collaboration and cooperation on research integrity cases. (shrink)

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Introduction to the translation of “De niet-theoretische voor-oordeelen in de wetenschap: Critiek op een oncritische critiek” by Herman Dooyeweerd (1938), Philosophia Reformata 3 (4), pp. 193–201.

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The origins of agriculture lie in the distant past, approximately 12 000 years ago, when hunter-gatherers of the Palaeolithic embraced sedentism at the dawn of the Neolithic. The variety of life history transitions emanating from this unique phenomenon have had an enormous impact on the biodiversity of the planet, while subjecting humanity to a variety of life-changing physical and social challenges right up to the present. The ever-present consequences of the Agricultural Revolution continue to demand our attention, yet frustrate our (...) efforts, on a seemingly perpetual basis, to effectively manage the outcomes. Here we review the origins and lasting after-effects of the Agricultural Revolution and its impact on the human condition, with reference to sedentism, nutrition, health issues, disease, gender discrimination as well as mythmaking and religion. Contribution: Our aim is to engage a wider audience with respect to the causes and consequences of the Agricultural Revolution. We discuss a broad spectrum of relevant phenomena implicated in this epochal event and consequently underline that the Agricultural Revolution precipitated not only major changes to the ecology of the planet, but also and most importantly to the social and cultural well-being of humanity. (shrink)

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In this empirical study, we investigate what and how teachers in Dutch universities of applied sciences (UAS) think they contribute to the development of students’ ethical compasses. Six focus groups were conducted with teachers across three programmes: Initial Teaching Education, Business Services, and Information and Communication Technology. This study revealed that teachers across the three different professional disciplines shared similar ideas about what should be addressed in the development of students’ ethical compasses. Their contributions were grouped into three core themes: (...) creating students’ moral awareness, developing students’ moral skills and promoting students’ moral professional behaviour. The majority of the teachers used a wide range of planned and unplanned pedagogic–didactic actions (reflecting individual learning and cooperative and group learning) to enhance the development of students’ ethical compasses. However, teachers’ strategies were mostly unstructured and unreflective and depended on the individual teacher’s ability and knowledge to address moral themes. Furthermore, the study revealed two incompatible ideals: as role models, the teachers aimed to exemplify explicitly how to be a professional with an ethical compass. However, they also wanted to adopt a neutral stance because they were afraid to manipulate the students’ ethical compasses. Therefore, they avoided promoting the ethical compass that they believed to be the best. (shrink)

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Introduction to the translation of “Het wijsgeerig tweegesprek tusschen de thomistische philosophie en de wijsbegeerte der wetsidee” by Herman Dooyeweerd (1948), Philosophia Reformata 13, pp. 26–31 and 49–58.

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The issue of free will is a complex one that has occupied the minds of many theologians and philosophers through the ages. The two main aspects of free will are the freedom to do otherwise and the power of self-determination. This means that an agent must be able to choose from alternative possibilities and that he or she must be the author or source of that choice. Defined as such, it is clear that the issue of free will is undeniably (...) closely linked with the concept of moral responsibility. However, if we live in a deterministic world, where everything is governed by the laws of nature, including our thoughts and behaviour, does this leave room for free will and moral responsibility? As Dutch neurobiologist and author Dick Swaab argues, the answer is an emphatic ‘no’. In this article, we will look at Swaab’s case against free will. We will also see what modern neuroscience has to say about this hot topic and whether it supports or discredits Swaab’s views. And finally, we will touch on what this all means for moral responsibility. Contribution: This article is part of a special collection that reflects on the evolutionary building blocks of our past, present and future. It is based on historical thought and contemporary research. It fits well with the intersectional and inter-disciplinary nature of this collection and journal. (shrink)

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In this article, focusing on the building blocks of art with its concomitant role and meaning, we commence with a brief evolutionary overview of the origin of land vertebrates, which culminated in the rise of our species as we view it. We then review three iconic phases of human evolution, colloquially designated as the Neanderthals, the San and the Cro-Magnons, as manifested by their artistic endeavours. We are well aware that the Cro-Magnons are currently regarded as not sufficiently distinct from (...) modern Homo sapiens to be separately designated. Therefore, the terms ‘anatomically modern humans’ or ‘early modern humans’ are suggested for these inhabitants of the Upper Palaeolithic as they shared an anatomical resemblance with us but still lacked the full complement of behavioural attributes that typify ourselves. This particular selection was chosen because these groups have partially overlapped historically, yet each represents a distinctive approach to the artistic impulse. Subsequently, we consider more contemporary developments regarding human art intertwined with our interpretation of art’s role and meaning. Then, we briefly discuss a broader account of the evolution of art in which these three phases are firmly based and through which our understanding of and engagement with the evolutionary development of these stages are elucidated and complemented. In conclusion, particular views about language and the role and meaning of art are confirmed. Particular views about language and the role and meaning of art are endorsed and supplemented by an extensive body of relevant literature.Contribution: This article explores the evolution of art and its accompanying role and meaning in an intersectional and interdisciplinary manner that fits well with the intention of this unique collection on the building blocks of our past, present and future and with the nature of this journal and our ongoing engagement with HTS Teologiese Studies/Theological Studies. (shrink)

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Background Outbreaks of infectious disease cause serious and costly health and social problems. Two new technologies – pathogen whole genome sequencing and Big Data analytics – promise to improve our capacity to detect and control outbreaks earlier, saving lives and resources. However, routinely using these technologies to capture more detailed and specific personal information could be perceived as intrusive and a threat to privacy. Method Four community juries were convened in two demographically different Sydney municipalities and two regional cities in (...) New South Wales, Australia to elicit the views of well-informed community members on the acceptability and legitimacy of: making pathogen WGS and linked administrative data available for public health researchusing this information in concert with data linkage and machine learning to enhance communicable disease surveillance systems Fifty participants of diverse backgrounds, mixed genders and ages were recruited by random-digit-dialling and topic-blinded social-media advertising. Each jury was presented with balanced factual evidence supporting different expert perspectives on the potential benefits and costs of technologically enhanced public health research and communicable disease surveillance and given the opportunity to question experts. Results Almost all jurors supported data linkage and WGS on routinely collected patient isolates for the purposes of public health research, provided standard de-identification practices were applied. However, allowing this information to be operationalised as a syndromic surveillance system was highly contentious with three juries voting in favour, and one against by narrow margins. For those in favour, support depended on several conditions related to system oversight and security being met. Those against were concerned about loss of privacy and did not trust Australian governments to run secure and effective systems. Conclusions Participants across all four events strongly supported the introduction of data linkage and pathogenomics to public health research under current research governance structures. Combining pathogen WGS with event-based data surveillance systems, however, is likely to be controversial because of a lack of public trust, even when the potential public health benefits are clear. Any suggestion of private sector involvement or commercialisation of WGS or surveillance data was unanimously rejected. (shrink)

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Introduction to the translation of “De beteekenis van de wijsbegeerte der wetsidee voor de theorie der menschelijke samenleving” by Herman Dooyeweerd, Philosophia Reformata 2, pp. 99–116.

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In this empirical study, we investigate _what_ and _how_ teachers in Dutch universities of applied sciences (UAS) think they contribute to the development of students’ ethical compasses. Six focus groups were conducted with teachers across three programmes: Initial Teaching Education, Business Services, and Information and Communication Technology. This study revealed that teachers across the three different professional disciplines shared similar ideas about what should be addressed in the development of students’ ethical compasses. Their contributions were grouped into three core themes: (...) creating students’ moral awareness, developing students’ moral skills and promoting students’ moral professional behaviour. The majority of the teachers used a wide range of planned and unplanned pedagogic–didactic actions (reflecting individual learning and cooperative and group learning) to enhance the development of students’ ethical compasses. However, teachers’ strategies were mostly unstructured and unreflective and depended on the individual teacher’s ability and knowledge to address moral themes. Furthermore, the study revealed two incompatible ideals: as role models, the teachers aimed to exemplify explicitly how to be a professional with an ethical compass. However, they also wanted to adopt a neutral stance because they were afraid to manipulate the students’ ethical compasses. Therefore, they avoided promoting _the_ ethical compass that they believed to be the best. (shrink)

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Human consciousness has been a hard problem for thousands of years and, in the course of time, variously interpreted and often too narrowly defined. As a result, the possibility of animal consciousness, sentience or even the possibility that animals can experience pain, received no, or very little, attention. Driven by the trope that animals lack the basic neural attributes to even experience pain, humans have seriously endangered the natural existence of untold multitudes of sentient organisms. However, humans are not the (...) only conscious organisms on the planet, as suggested by a variety of research results, attesting to the fact that even lower vertebrates possess sentience and feel pain. Multiple research findings have now stressed the need for a phylogenetic approach to consciousness, which, in the long run, will have extensive theological implications. Succinctly put, these findings indicate that we live in a world of minds, and that only some of them are human. Contribution: This article is part of a special collection that reflects fundamentally on the origin and evolution of the universe as well as what the future possibly might hold. It is based on historical thought and contemporary research. Different, conflicting sources are being interpreted, and the research approach is in line with the intersectional and interdisciplinary nature of this journal. We do not directly engage theology and religion, although the research and empirical data are underpinned by a moral imperative that cannot be avoided by theological and religious disciplines. (shrink)

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PurposeTo explore the mindfulness practice, its long-term effects, facilitators and barriers, in clinical clerkship students 2 years after participation in an 8-week mindfulness-based stress reduction training.MethodA qualitative study was performed by semi-structured in-depth interviews with 16 clinical clerkship students selected by purposive sampling. Students had participated in a MBSR training 2 years before and were asked about their current mindfulness practice, and the long-term effects of the MBSR training. Thematic analysis was conducted using the constant comparison method. Data saturation was (...) reached after 16 interviews.ResultsMost interviewees were still engaged in regular, predominantly informal, mindfulness practice, although some discontinued mindfulness practice and reported an “unchanged lifestyle.” Three main themes came forward; “focused attention and open awareness” during daily activities as core elements of long-term mindfulness practice; “changes in behavior and coping” that resulted from taking a pause, reflecting, recognizing automatic behavioral patterns and making space for a conscious response; “integration in personal and professional life” by enhanced enjoyment of daily activities, improved work-life-balance and making different career choices. Barriers and facilitators in starting and maintaining mindfulness practice were understanding and intention as “pre-conditions”; practical, personal, and professional factors of students in maintaining practice.ConclusionTwo years after participation in a MBSR training, many interviewees were still engaged in mindfulness practice contributing to both personal and professional changes. In light of the high clerkship demands, MBSR training could be a valuable addition to medical curricula, supporting medical students in developing necessary competencies to become well-balanced professionals. (shrink)

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Introduction to the translation of “De beteekenis van de wijsbegeerte der wetsidee voor de theorie der menschelijke samenleving” by Herman Dooyeweerd, Philosophia Reformata 2, pp. 99–116.

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Introduction to the translation of “De transcendentale critiek van het wijsgeerig denken en de grondslagen van de wijsgeerige denkgemeenschap van het avondland” by Herman Dooyeweerd (1941), Philosophia Reformata 6 (1), pp. 1–20.

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We focus on two issues: (1) an unusual, counterintuitive prediction that quantum probability (QP) theory appears to make regarding multiple sequential judgments, and (2) the extent to which QP is an appropriate and comprehensive benchmark for assessing judgment. These issues highlight how QP theory can fall prey to the same problems of arbitrariness that Pothos & Busemeyer (P&B) discuss as plaguing other models.

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Brain imaging studies have consistently shown subgenual Anterior Cingulate Cortical (sgACC) involvement in emotion processing. COMT Val158 and Met158 polymorphisms may influence such emotional brain processes in specific ways. Given that resting-state fMRI (rsfMRI) may increase our understanding on brain functioning, we integrated genetic and rsfMRI data and focused on sgACC functional connections. No studies have yet investigated the influence of the COMT Val158Met polymorphism (rs4680) on sgACC resting-state functional connectivity (rsFC) in healthy individuals. A homogeneous group of sixty-one Caucasian (...) right-handed healthy female university students, all within the same age range, underwent rsfMRI. Compared to Met158 homozygotes, Val158 allele carriers displayed significantly stronger rsFC between the sgACC and the left parahippocampal gyrus, ventromedial parts of the inferior frontal gyrus, and the nucleus accumbens (NAc). On the other hand, compared to Val158 homozygotes, we found in Met158 allele carriers stronger sgACC rsFC with the medial frontal gyrus, more in particular the anterior parts of the medial orbitofrontal cortex. Although we did not use emotional or cognitive tasks, our sgACC rsFC results point to possible distinct differences in emotional and cognitive processes between Val158 and Met158 allele carriers. However, the exact nature of these directions remains to be determined. (shrink)

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Directly after his first article for Philosophia Reformata (Dooyeweerd 1936a), Dooyeweerd published a long article in two installments about cosmic time. The first was entitled “Het tijdsprobleem en zijn antinomieën op het immanentiestandpunt i” (Dooyeweerd 1936b); its translation, entitled “The Problem of Time and Its Antinomies on the Immanence Standpoint,” was later published in Dooyeweerd (2017). This first installment lays out the basis of Dooyeweerd’s idea of transcendental time and can be regarded as a complete article in itself. According to (...) Dooyeweerd (1953–1958, 1:28), the idea of cosmic time constitutes the basis of his theory of reality. In this article, we will take a close look at the significance of cosmic time in Dooyeweerd’s conception. (shrink)

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An increasing number of cultural heritage institutions publish data online. Ontologies can be used to structure published data, thereby increasing interoperability. To achieve widespread adoption o...

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