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Interoceptive processes emanating from baroreceptor signals support emotional functioning. Previous research suggests a unique link to fear: fearful faces, presented in synchrony with systolic baro...

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Mitochondrial replacement techniques have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer and Maternal Spindle Transfer. It examines how questions of identity impact (...) on the ethical evaluation of each technique and argues that there is an important difference between the two. PNT, it is argued, is a form of therapy based on embryo modification while MST is, instead, an instance of selective reproduction. The article's main ethical conclusion is that, in some circumstances, there is a stronger obligation to use PNT than MST. (shrink)

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Non-Identity arguments have a pervasive but sometimes counter-intuitive grip on certain key areas in ethics. As a result, there has been limited success in supporting the alternative view that our choices concerning future generations can be considered harmful on any sort of person-affecting principle. However, as the Non-Identity Problem relies overtly on certain metaphysical assumptions, plausible alternatives to these foundations can substantially undermine the Non-Identity argument itself. In this paper, I show how the pervasive force and nature of Non-Identity arguments (...) rely upon a specific adoption of a theory of modality and identity and how adopting an alternative account of modality can be used to reject many conclusions formed through Non-Identity type arguments. By using Lewis’s counterpart-theoretic account to understand ways we might have been, I outline the basis of a modal account of harm that incorporates a person-affecting aspect. This, in turn, has significant implications for ethical decision-making in areas such as reproductive choice and the welfare of future generations. (shrink)

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The concept of vulnerability has been subject to numerous different interpretations but accounts are still beset with significant problems as to their adequacy, such as their contentious application or the lack of genuine explanatory role for the concept. The constant failure to provide a compelling conceptual analysis and satisfactory definition leaves the concept open to an eliminativist move whereby we can question whether we need the concept at all. I highlight problems with various kinds of approach and explain why a (...) satisfactory account of vulnerability is unlikely ever to be offered if we wish the concept to play a genuinely explanatory role in bioethical contexts. I outline why an eliminativist position should be taken with regard to this concept in light of these concerns but mitigate some of the severity of this position by arguing that we can still make sense of retaining our widespread use of the term by viewing it as nothing more than a useful pragmatic linguistic device that acts as a marker to draw attention to certain kinds of issue. These issues will be entirely governed by other, better understood ethical concepts and theories. (shrink)

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Recent legal rulings concerning the status of advance statements have raised interest in the topic but failed to provide any definitive general guidelines for their enforcement. I examine arguments used to justify the moral authority of such statements. The fundamental ethical issue I am concerned with is how accounts of personal identity underpin our account of moral authority through the connection between personal identity and autonomy. I focus on how recent Animalist accounts of personal identity initially appear to provide a (...) sound basis for extending the moral autonomy of an individual - and hence their autonomous wishes expressed through an advance directive - past the point of severe psychological decline. I argue that neither the traditional psychological account nor the more recent Animalist account of personal identity manage to provide a sufficient basis for extending our moral autonomy past the point of incapacity or incompetence. I briefly explore how analogies to similar areas in law designed to facilitate autonomous decision, such as wills and trusts, provide at best only very limited scope for an alternative justification for granting advance statements any legal or moral authority. I conclude that whilst advance statements play a useful role in formulating what treatment is in a patient’s best interests, such statements do not ultimately have sufficient moral force to take precedence over paternalistic best interest judgements concerning an individual’s care or treatment. (shrink)

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The Liverpool Care Pathway for the Dying has recently been the topic of substantial media interest and also been subject to the independent Neuberger Review. This review has identified clear failings in some areas of care and recommended the Liverpool Care Pathway be phased out. I argue that while the evidence gathered of poor incidences of practice by the Review is of genuine concern for end of life care, the inferences drawn from this evidence are inconsistent with the causes for (...) the concern. Seeking to end an approach that is widely seen as best practice and which can genuinely deliver high quality care because of negative impressions that have been formed from failing to implement it properly is not a good basis for radically overhauling our approach to end of life care. I conclude that improvements in training, communication, and ethical decision-making, without the added demand to end the Liverpool Care Pathway would have resulted in a genuine advance in end of life care. (shrink)

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Visual research methods like photography and digital storytelling are increasingly used in health and social sciences research as participatory approaches that benefit participants, researchers, and audiences. Visual methods involve a number of additional ethical considerations such as using identifiable content and ownership of creative outputs. As such, ethics committees should use different assessment frameworks to consider research protocols with visual methods. Here, we outline the limitations of ethics committees in assessing projects with a visual focus and highlight the sparse knowledge (...) on how researchers respond when they encounter ethical challenges in the practice of visual research. We propose a situated approach in relation to visual methodologies that encompasses a negotiated, flexible approach, given that ethical issues usually emerge in relation to the specific contexts of individual research projects. Drawing on available literature and two case studies, we identify and reflect on nuanced ethical implications in visual research, like tensions between aesthetics and research validity. The case studies highlight strategies developed in-situ to address the challenges two researchers encountered when using visual research methods, illustrating that some practice implications are not necessarily addressed using established ethical clearance procedures. A situated approach can ensure that visual research remains ethical, engaging, and rigorous. (shrink)

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Anthony Simon Laden explores the kind of reasoning we engage in when we live together: when we are responsive to others and neither commanding nor deferring to them. He argues for a new, social picture of the activity of reasoning, in which reasoning is a species of conversation--social, ongoing, and governed by a set of characteristic norms.

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Parfit’s (1984) Non-Identity Problem provides a strong line of argument that we cannot be harmed by pre-conception choices or actions. I argue that we can no longer appeal to the Non-Identity problem in order to justify using pre-conception genetic screening and selection techniques as a harmless tool to determine the genetic constitution of future individuals. My criticism of the Non-Identity problem is based on a rejection of the metaphysical foundations of Parfit’s argument - Kripke’s (1980) essentialist arguments for the necessity (...) of origin. I offer an alternative account of modal harms based on counterpart theory such as that offered by David Lewis (1986). On this account, individuals can make legitimate harm claims in regard to pre-conception choices made in determining their genetic constitution by appeal to their counterparts across possible worlds. (shrink)

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The standard by which we apply decision-making for those unable to do so for themselves is an important practical ethical issue with substantial implications for the treatment and welfare of such individuals. The approach to proxy or surrogate decision-making based upon substituted judgement is often seen as the ideal standard to aim for but suffers from a need to provide a clear account of how to determine the validity of the proxy's judgements. Proponents have responded to this demand by providing (...) the truth-conditions for the substituted judgement in terms of counterfactual reasoning using a possible worlds semantics. In this paper, I show how these underpinnings fail to support the substituted judgement approach as a reasonable standard for decision-making. Firstly, I show how this counterfactual element has been poorly interpreted. I then explain how various accounts have failed to reflect problems and limitations associated with providing an interpretation of their truth-conditions using counterfactuals. Finally, I argue that, even when we attend to the initial problems of providing a counterfactual analysis, it still deeply problematic as a means of determining the validity of substituted judgements for two main reasons. Firstly, making determinate judgements as to the truth-value of these judgements will often not be possible and, secondly, there is a strong requirement when interpreting many counterfactual claims to charitably accede to their being true. I conclude that substituted judgements, as interpreted through counterfactual reasoning and possible worlds semantics, do not therefore provide an adequate standard for surrogate decision-making. (shrink)

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IntroductionExtended decision -making through the use of proxy decision -makers has been enshrined in a range of International Codes, Professional Guidance and Statute,For example, the UK Mental Capacity Act section 9.1; The General Medical Council ; the US National Guardianship Association ; Nuffield Council on Bioethics ; CIOMS-WHO section 6. Court cases such as Re Quinlan in the US have also contributed to establishing the groundings for the legal status of the proxy, albeit in terms of who might be suitable (...) as a proxy in cases where there was no clear appointment of them by a still competent individual. and is now widely seen as a useful means through which we can exercise control over decisions that affect our lives when we have lost capacity to make these decisions for ourselves.I will here limit myself to discussion of proxy consent for adults appointed prior to the loss of competence by the person they are acting as proxy for. The issue of p. (shrink)

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This open peer commentary critiques Cwik's approach to categorizing germline gene editing interventions. The authors argue that Cwik's framework, which prioritizes technical categories and dimensions to map the "ethical terrain," is fundamentally flawed by putting the technical aspects before ethical considerations. They identify four key problems with his approach: it is arbitrary in its categorizations, relies on dynamic membership that changes with scientific knowledge, requires extensive technical expertise that many bioethicists lack, and most importantly, approaches the analysis "back-to-front" by starting (...) with technical rather than ethical distinctions. The authors argue that ethical assessment should begin with examining the goals and justifications of an intervention, rather than its technical specifications. They use the example of mitochondrial replacement therapy to illustrate how classification should proceed from ethical considerations to technical ones, not vice versa. The commentary concludes that while Cwik offers a complex framework, it is both incorrectly structured and impractical to use consistently. (shrink)

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Anthony J. Lisska presents a new analysis of Thomas Aquinas's theory of perception. While much work has been undertaken on Aquinas's texts, little has been devoted principally to his theory of perception and less still on a discussion of inner sense. The thesis of intentionality serves as the philosophical backdrop of this analysis while incorporating insights from Brentano and from recent scholarship. The principal thrust is on the importance of inner sense, a much-overlooked area of Aquinas's philosophy of mind, (...) with special reference to the vis cogitativa. Approaching the texts of Aquinas from contemporary analytic philosophy, Lisska suggests a modest 'innate' or 'structured' interpretation for the role of this inner sense faculty. He argues that were it not for the vis cogitativa, Aquinas would be unable to account for an awareness of the principal ontological category in his metaphysics. (shrink)

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From the late-fifteenth century onwards, scholars across Europe began to write books about how to read and evaluate histories. These pioneering works - which often take surprisingly modern-sounding positions - grew from complex early modern debates about law, religion, and classical scholarship. In this book, based on the Trevelyan Lectures of 2005,Anthony Grafton explains why so many of these works were written, why they attained so much insight - and why, in the centuries that followed, most scholars gradually (...) forgot that they had existed. Elegant and accessible, What Was History? is a deliberate evocation of E. H. Carr’s celebrated and icononclastic Trevelyan Lectures on What Is History?, and will appeal to a broad readership of students, scholars and historical enthusiasts.Anthony Grafton is one of the most celebrated historians writing in English today, and What Was History? is a powerful and imaginative exploration of some central themes in the history of European ideas. (shrink)

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In this paper I provide an account of the metaphysical foundations of mental illness in terms of a realism debate. I motivate the importance of such metaphysical analysis as a means of avoiding some intractable problems that beset discussion of the concept of mental illness. I apply aspects of the framework developed by Crispin Wright for realism debates in order to examine the ontological commitments to mental illness as a property that humans may exhibit and to examine the various arguments (...) that realists and anti-realists can use to defend their position on mental illness. I pay particular attention to characterising Szasz's account of mental illness as that of an anti-realist error-theory and present ways in which a realist may counter such a position. Ultimately I argue that in order to hold a realist position on mental illness one would have to adopt some form of realism towards values, such as moral realism. (shrink)

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A phenomenological account of the forms of life characteristic of late capitalism--including television, celebrity culture, and personal electronics--culminating in an ontology of the gadget-commodity that brings together Marxist theories of commodity fetishism and ideology with Heidegger's attempt to think truth as unconcealment.

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Taking its departure from the historical intertwinement of the concepts of crisis and disease, this paper argues that Wittgenstein’s therapeutic model of philosophy, despite its seemingly ahistorical tendencies, develops around the concept of crisis; while philosophy itself, even in its dogmatic forms, can always be understood as a therapy for disease-prone life, Wittgenstein’s project addresses the cancerous tendency of metaphysics, originally itself a kind of therapy, to proliferate pseudo-answers to pseudo-questions. But in contrast to those critical philosophers who uphold a (...) “criterion” such as possible experience (Kant) or falsifiability (Carnap), Wittgenstein, in later writings such as the Philosophical Investigations, confronts the crisis of the absence of such criteria; rather than elevating forms of life and language games to a new criterion, he calls us to renounce the need for criteria. This, in turn, suggests an analogy with the twelve-step approach to addiction, itself rooted in a conception of the radical non-hierarchical structure of early Christian communities as well as Augustine’s notions of faith as overcoming the fundamental incapacity of the will. Wittgenstein’s philosophical therapy is a self-therapy that originates in an experience of the crisis of criteria for critique – a crisis that itself arises from the failure of the ethics of moderation, the lack of the obscure yet concrete measure of communal life. The extreme experience of the failure of criteria to find a way out from crisis, as when the addict recognizes that will is powerless over addiction, becomes the springboard for a form of existence based on a new community, existing outside the dream of endless progress, in which new habits become again possible. (shrink)

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Santayana, whose early writings are hostile to the Faustian spirit, used a quotation from IFaust, Part IID as epigraph to IThe Realm of SpiritD. This suggest a possible affinity of late Santayana, and aspects of Goethe. The speech of the Earth-Spirit in IFaustD has an amoralism similar to passages in IThe Realm of MattesD. A certain ironical, detached spirituality links the poet-sages as well. Each uses some of the symbolism of Christian dogma (e.g., the last chapter of IThe Realm of (...) SpiritD and the end of IFaust, Part IID) to convey the religious mystery of existence, but with no strict adherence to Christianity. (shrink)

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Abstract Sam Peltzman has brought discipline and common sense to economic analyses of voting and representation. Yet his approach suffers, like that of other economists, from disciplinary provincialism and a singular devotion to econometrics as a research methodology. Political science offers alternative models and research methods that can enliven and deepen the political analyses of Peltzman and other economists.

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Drawing on and developing the phenomenological work of figures such as Edmund Husserl and Max Scheler, Knowing by Heart details the various feelings and feeling states that pertain to matters of the heart.

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This volume offers perspectives on the theme of surprise crossing philosophical, phenomenological, scientific, psycho-physiology, psychiatric, and linguistic boundaries. The main question it examines is whether surprise is an emotion. It uses two main theoretical frameworks to do so: psychology, in which surprise is commonly considered a primary emotion, and philosophy, in which surprise is related to passions as opposed to reason. The book explores whether these views on surprise are satisfying or sufficient. It looks at the extent to which surprise (...) is also a cognitive phenomenon and primitively embedded in language, and the way in which surprise is connected to personhood, the interpersonal, and moral emotions. Many philosophers of different traditions, a number of experimental studies conducted over the last decades, recent works in linguistics, and ancestral wisdom testimonies refer to surprise as a crucial experience of both rupture and openness in bodily and inner life. However, surprise is a theme that has not been dealt with directly and systematically in philosophy, in the sciences, in linguistics, or in spiritual traditions. This volume accomplishes just that. (shrink)

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In ‘Semantic Foundations for the Logic of Preference’ (Rescher, ed.,The Logic of Decision and Action, University Press, Pittsburgh, 1967), Nicholas Rescher claims that, on the semantics developed in that paper, a certain principle - call it ‘Q’ turns out to be ‘unacceptable’. I argue, however, that, given certain assumptions that Rescher invokes in that same paper,Q can in fact be shown to be a ‘preference-tautology’, and henceQ should be classified as ‘acceptable’ on Rescher's theory.

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The nutrition transition concept developed by Popkin has gained wide currency within the nutritional sciences literature as a way of understanding population wide changes to diet and energy balance and their related health outcomes in society. It offers a useful template of different nutritional patterns societies progress through, but it has not provided a comprehensive understanding of the why and how of dietary change. Building on insights from the literature on food regimes in the social sciences, this paper argues the (...) concept of dietary regimes can augment the nutrition transition model and can serve as a bridge between social and health sciences around nutrition and dietary change. The political economy analysis of the dietary regime approach provides insights into the historical degradation of food and the diffusion of nutrient-poor products throughout food environments today. It also engages analysis of the key actors shaping food environments and diets in the industrial era. The dietary regime approach can provide fruitful directions with respect to concrete policy options to address the major issue of population wide weight gain that the nutrition transition model has sought to confront in recent iterations. (shrink)

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In the context of two examples from child conversation the author exemplifies the kinds of attributional process that can be uncovered through detailed examination of interaction. Although these processes implicate an orientation to psychological states by the child their specification does not depend on claims regarding the child’s cognitive processes. Nevertheless this specification can have a bearing on the adequacy of theories of cognitive processes, by locating competences that such theories should be able to account for. These issues are related (...) to research on ‘theory of mind’, discursive psychology and Vygotskyan psychology. (shrink)

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The article outlines the diverse willed and unwilled developments which have attenuated international human rights discourse so that it still cannot be used to hold governments to account for their failures to respect the economic and social rights of their citizens. These developments range from geopolitical manoeuvres, through changed modes of enunciation , to the absence of appropriate governmentalist techniques for measuring economic and social compliance. It then questions and counters the doctrine of `justiciability' that is the discursive node of (...) this structure of impotence. It concludes by proposing a strategy for the development of a more truly cosmopolitan international human rights discourse. (shrink)

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Gittins,Anthony Sailing ships and boats, and the sailors who navigate them, depend mightily upon the wind; without it they remain in the doldrums, floating aimlessly. Without wind, all the sailors' experience and ingenuity is of absolutely no help. But if the wind should get up and blow against them - directly head-on or broadside - it can destroy and sink even the biggest boats and surest sailors. So navigators must learn to read the wind carefully and with respect, (...) and to interpret and respond to it appropriately. Fighting against the might of the wind is ultimately a lost cause. (shrink)

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Gittins,Anthony J By its achievements and the transformations that would not have happened without it, Alcoholics Anonymous has always impressed me, as do the people who belong to it. And yet there is little structure, few rules, and no rush to judgment involved. It is a 'fellowship' rather than an organisation, and a society of peers rather than a clash of personalities. Its success is attributed to the sharing of experiences, the moral support of the sponsors and the (...) community, the strength and determination - rather than the weakness or the history - of its members, and the sense of hope it inspires and maintains in those who refuse to give up, one day at a time. To admit or acknowledge powerlessness over alcohol or any addiction is not to identify oneself as without all power. On the contrary, those who acknowledge weakness in one area and yet show determination succeed partly because of the power of the wider group and partly because of the power of their own personal dedication and perseverance. Members of AA know that they are only a day or a drink from disaster, and yet, curiously, this is their strength; by keeping that awareness clearly before them, they are unlikely to become arrogant or independent of a support group. (shrink)

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Gittins,Anthony J It is impossible for anyone to feel the pain you feel; the most people can do is to sympathise or empathise. But because there is nothing new under the sun, all of us can at least try to 'suffer with' the sufferings of others. Our experience of the all too human failings of the church today is by no means unique: ever since the beginning, times of trauma and crisis have alternated with times of peace and (...) healing. Our challenge is to keep hope alive during times of crisis, and to learn from the past in order learn its lessons and not repeat its mistakes. In this final reflection, I offer some reasons for hope and some perspectives for the next stage of our lives if it is to be marked by faithfulness and action rather than fear and reaction. (shrink)

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