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The article is devoted to the analysis of “psychological” argument for the existence of God of Viktor Nesmelov, professor of Kazan Theological Academy, represented in his fundamental work “Science of Man”. The main interpretations of this argument, formulated both contemporaries of Nesmelov ) and modern researchers of his legacy are considered. The basic prerequisites and origins of Nesmelov’s anthropological doctrine are analyzed. The main of them were V. Snegiryov’s psychological doctrine and anthropological ideas of St. Gregory of Nyssa. The main (...) ideas of Nesmelov’s Christian anthropology, related directly to his formulation of “the idea of God”, etc.) are revealed. Besides that, Nesmelov’s criticism of the main existing arguments for the existence of God is analyzed. The main conclusion based on the analysis of Nesmelov’s anthropological system is made: his argument for the existence of God represents rather a methodological program for creating such argument in the future. The base of this argument should be made of not only by an “ abstract knowledge”, but the “living worldview” and the “living unity of God and man”. (shrink)

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У статті, на прикладі дослідження наукової тематики кафедри, висвітлюється можливі механізми оцінки інноваційного потенціалу наукової установ та її складових частин. Підкреслюється необхідність розвитку науки, як життєво необхідного фактору для нормальної роботи всіх сфер держави, а також створення найбільш комфортних соціально-побутових умов для населення, відповідно до європейського рівня розвитку суспільства. Метою дослідження є розробка методичних положень щодо оцінки інноваційного потенціалу наукової діяльності наукових установ, як фактора збільшення інвестиційної вартості науки на ринку наукових послуг України. Завданнями є: узагальнення особливостей інноваційного потенціалу наукових (...) установ ; формулювання теоретичних визначень інноваційного потенціалу, інноваційної діяльності; обґрунтування необхідності моделювання процесів оцінювання інноваційного потенціалу наукової діяльності тощо. Виходячи з актуальності обраної теми ставиться мета, формулюються завдання. Методологічну основу дослідження складає сукупність загальновизнаних принципів та методів наукового пізнання. Для отримання наукових результатів застосовувалися загальнонаукові принципи та підходи, які забезпечили єдність аналізу, історизм, об’єктивність дослідження тощо. Робиться висновок про те, що надійне та ефективне застосування наукових розробок у багатьох сферах є основою поступального розвитку економіки країни та представляє невід’ємну складову забезпечення цивілізованих умов життя всіх її громадян. Пропонується ряд змін до чинного законодавства, а саме до Закону України «Про наукову та науково-технічну експертизу», «Про державне регулювання діяльності у сфері трансферу технологій». Зауважується на тому, що на тлі змін ролі науки і техніки та високих технологій в житті людства питання вивчення інноваційного потенціалу науки набувають особливої актуальності. Та незважаючи на великий інтерес до усебічного вивчення напрямів розвитку науки, до сих пір не врегульовано єдиних загальних підходів до його оцінювання. (shrink)

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We investigate particular cosmological models, based either on tachyon fields or on perfect fluids, for which soft future singularities arise in a natural way. Our main result is the description of a smooth crossing of the soft singularity in models with an anti-Chaplygin gas or with a particular tachyon field in the presence of dust. Such a crossing is made possible by certain transformations of matter properties. We discuss and compare also different approaches to the problem of crossing of the (...) Big Bang–Big Crunch singularities. (shrink)

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In this study, we examine the nature of the relationship between ethical leadership and unethical pro-organizational behavior (UPB), defined as unethical behavior conducted by employees with the aim of benefiting their organization, and whether the strength of the relationship differs between subordinates experiencing high and low identification with supervisor. Based on three-wave survey data obtained from 239 public sector employees in China, we find that ethical leadership has an inverted u-shaped (curvilinear) relationship with UPB. As the level of ethical leadership (...) increases from low to moderate, UPB increases; as the level of ethical leadership increases from moderate to high, UPB decreases. Further, we find that the strength of this inverted u-curve relationship differs between subordinates with high and low identification with supervisor. That is to say, the inverted u-shaped relationship between ethical leadership and UPB was stronger when subordinates experienced high levels of identification with supervisor. The theoretical and managerial implications of our findings for understanding how to manage UPB in an organizational context are discussed. (shrink)

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Recent work indicates that there are distinct response habituation mechanisms that can be recruited by different stimulation rates and that can underlie different components (e.g., the duration or speed) of a single behavioral response. These findings raise the question: why is “the simplest form of learning” so complicated mechanistically? Beyond evolutionary selection for robustness of plasticity in learning to ignore, it is proposed in this article that multiple mechanisms of habituation have evolved to streamline shifts in ongoing behavioral strategy. Then, (...) speculations are offered regarding the implications of this reconceptualization of habituation for approaching the analysis of mechanisms of more complex forms of learning and memory. (shrink)

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Coming fromI andCl, i.e. from intuitionistic and classical propositional calculi with the substitution rule postulated, and using the sign to add a new connective there have been considered here: Grzegorozyk's logicGrz, the proof logicG and the proof-intuitionistic logicI set up correspondingly by the calculiFor any calculus we denote by the set of all formulae of the calculus and by the lattice of all logics that are the extensions of the logic of the calculus, i.e. sets of formulae containing the axioms (...) of and closed with respect to its rules of inference. In the logiclG the sign is decoded as follows: A = (A & A). The result of placing in the formulaA before each of its subformula is denoted byTrA. The maps are defined (in the definitions of x and the decoding of is meant), by virtue of which the diagram is constructed. (shrink)

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The main article is devoted to the historical and philosophical reconstruction of controversy between Vladimir Solovyov and the authors of the “Faith and Reason” - a magazine of the Kharkov Theological Seminary. This controversy took its place in the “theological and journalistic” or the “theocratic” period of Solovyov’s works. Particular attention is paid to the disputes of Solovyov and T. Stoyanov, A.P. Shost'in and the French Orthodox priest Fr. Vladimir Gette on the theory of dogmatic development in the church. In (...) the context of this controversy, the arguments for the “defense” of Solovyov's position, cited in the magazine “Orthodox Review” by a theologian and Konstantin Leontyev's follower Ivan Kristi are also analyzed. The reception of Solovyov's theocratic ideas and reaction to his ecclesiastical views in both the Catholic and Orthodox circles of Russian and Western society is shown. Especially it concerns the criticism of Solovyov’s ideas in the pages of the French magazines “L’Univers”, “L'Union Chrétienne”, “Revue d’Eglise greque-unie”, etc. The evolution of Solovyov's views on the problem of the union of Eastern and Western churches, the renewal of church communication between Orthodoxy and Catholicism, the main result of which was his fundamental but unfinished work “The History and Future of the Theocracy” was demonstrated. A conclusion about the “superficiality” of the judgments of the majority of Vladimir Solovyov's ideological opponents, as well as later interpreters of his legacy, following the French Jesuit Michel d'Erbigny, who tried to present him as a “Russian Newman” who converted from Orthodoxy into the Catholic faith is drawn. It is shown that Solovyov’s projects of the “religion of the Holy Spirit” and the “Universal Church”, created on its basis, should be considered primarily in the context of his own philosophical quest, and not in connection with the confessional and ideological divergences of his time. (shrink)

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In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identification. Given the large quantity of information being obtained in this area, there emerges an urgent need to integrate what is being discovered by a broad range of relevant communities. To this end, the Non-Coding RNA Ontology (NCRO) is being developed to provide a systematically structured and precisely defined controlled vocabulary for the (...) domain of ncRNAs, thereby facilitating the discovery, curation, analysis, exchange, and reasoning of data about structures of ncRNAs, their molecular and cellular functions, and their impacts upon phenotypes. The goal of NCRO is to serve as a common resource for annotations of diverse research in a way that will significantly enhance integrative and comparative analysis of the myriad resources currently housed in disparate sources. It is our belief that the NCRO ontology can perform an important role in the comprehensive unification of ncRNA biology and, indeed, fill a critical gap in both the Open Biological and Biomedical Ontologies (OBO) Library and the National Center for Biomedical Ontology (NCBO) BioPortal. Our initial focus is on the ontological representation of small regulatory ncRNAs, which we see as the first step in providing a resource for the annotation of data about all forms of ncRNAs. (shrink)

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Sri Lanka completed eloquent pull Dage described the love of wisdom is a holistic, practical way of life, which of course requires an abstract, theoretical science of meditation, more importantly, it also contains many religious practices is legal, such as flexible do not rot the soul, bitter conduct regular ring legal, social and political reform program, sustained ethics reflection, body control, dietary rules and taboos. However, this Pythagorean philosophy as a better life to all the light and fade away In (...) order to view at any time. The original philosophy of travel to another utterly abnormal interest in the pilgrimage of the way, that is abstract, a clear knowledge and commitment of this knowledge by the certainty of pursuit. "Knowledge" and "real management" into the vocabulary of philosophy In order systems, "smart" In order to become a college corridor in the West has been seriously neglected under the words. With the flow of time driving on the theory and psychiatric abstract admiration, which means practical wisdom, rhetoric and aesthetics into a whole都In order to two yuan regardless. Philosophy - the "love of wisdom" - in all intent and purposes都becomes In order to philo-episteme-"love of knowledge certainty." Started with the ancient Chinese culture, hope臘different. It is rooted in Confucianism, "the next school on up," the admonition of Chinese philosophy from the initial thinking on the road from the daily behavior persist in the pursuit of wisdom, relationships conducted by the "self" as the meaning of things by the event source. Everyone from family, community, political relations, to obtain a unique perspective, they participate in the growth of sperm heart and minds of thinking, their family and community relationships to adjust to a clearer, more meaningful position. Personal self-cultivation increased by the universe meaning, and meaning of the universe has increased over the coming anti-In order for individuals to provide a self fertile soil. For the eloquent Pythagoras, the holistic way of life he described as philosophia-"the love of wisdom"-while entailing the contemplation of abstract, theoretical science, involved much more importantly religious practices based upon the immortality of the soul, ascetic observances, a program of social and political reform, ethical reflection, a physical regimen, and even dietary prescriptions and prohibitions. But this conception of philosophy as a holistic vision of the good life faded in time, and gave way to the search for apodictic knowledge and its promise of certainty. "Knowledge" and "truth" became the vocabulary of systematic philosophy, and "wisdom" was banished from conversation in the corridors of the Western academy. The worship of the theoretically and spiritually abstract meant that in the fullness of time practical wisdom , rhetoric, and the aesthetic were relegated to the down side of a prevailing dualism. The Chinese cultural narrative unfolded differently. Grounded in the Confucian exhortation-"Study what is near at hand and aspire to what is lofty the next school on the up"-the Chinese philosophical narrative has from earliest times sustained a commitment to the pursuit of wisdom by understanding personal cultivation as the ultimate source of an emergent cosmic meaning. It is the revolution currently taking place within the Western philosophical community as an attempt to reinstate wisdom that provides an opening and an invitation to take Chinese philosophy and culture more seriously. An internal critique continues to be waged within professional Western philosophy under the many banners of process philosophy, hermeneutics, post-modernism, neo-pragmatism, neo-Marxism, deconstructionism, feminist philosophy , and so on, that takes as a shared target what Robert Solomon has called "the transcendental pretense"-idealism, objectivism, logocentrism, essentialism, the master narrative, "the myth of the given"-the familiar reductionistic "isms" that have emerged as putatively novel choices as philosophers switch horses on the merry-go-round of systematic philosophy. In place of a Cartesian philosophical language that privileges the function of clear and distinct ideas in our quest for an objective certainty, vocabularies of process, change, and indeed productive vagueness have increasingly come into vogue. These recent developments in Anglo-European philosophy itself have begun to foreground interpretative vocabularies more relevant to the articulation of Chinese culture. In this essay, I will argue that the pragmatic theory of truth as expounded by William James and particularly John Dewey is an attempt to reauthorize "wisdom" as a philosophical goal in the Western philosophical narrative. This development opens a space for a conversation between Deweyan pragmatism and Confucianism on how best to achieve it. (shrink)

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The Blackwell Dictionary of Western Philosophy is a concise reference to the whole history of western philosophy, from ancient Greece to the present day. Spans all the major branches of western philosophical inquiry, all of the key figures Explains the meaning and usage of each philosophical concept in a fresh and engaging style Each entry on philosophical terms concludes with an illustrative quotation from a significant philosopher, to enhance the reader’s understanding Entries on terms and individual philosophers are fully cross-referenced (...) Co-written by the editor of the popular volume The Blackwell Companion to Philosophy (Second Edition, 2002). (shrink)

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We examine the influence of inferring interlocutors' referential intentions from their body movements at the early stage of lexical acquisition. By testing human participants and comparing their performances in different learning conditions, we find that those embodied intentions facilitate both word discovery and word‐meaning association. In light of empirical findings, the main part of this article presents a computational model that can identify the sound patterns of individual words from continuous speech, using nonlinguistic contextual information, and employ body movements as (...) deictic references to discover word‐meaning associations. To our knowledge, this work is the first model of word learning that not only learns lexical items from raw multisensory signals to closely resemble infant language development from natural environments, but also explores the computational role of social cognitive skills in lexical acquisition. (shrink)

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COVID-19 has created significant concern surrounding the impact of pandemic lockdown on mental health. While the pandemic lockdown can be distressing, times of crisis can also provide people with the opportunity to think divergently and explore different activities. Novelty seeking, where individuals explore novel and unfamiliarly stimuli and environments, may enhance the creativity of individuals to solve problems in a way that allows them to adjust their emotional responses to stressful situations. This study employs a longitudinal design to investigate changes (...) in novelty seeking and mental health outcomes before, during, and after COVID-19 pandemic lockdown, among a group of students from a university in southeast China. Participants were surveyed at three points: November, 2019 ; between February and March, 2020 ; and between May and June, 2020. Cross-sectionally, correlation analysis indicated that greater novelty seeking was associated with lower levels of stress, anxiety, and depression at all three time points. Univariate latent curve modeling indicated a growth trajectory in which novelty seeking increased over time and then remained high during the post-lockdown period. Stress, anxiety, and depression all showed V-shaped growth trajectories in which these variables decreased during lockdown, before increasing in the post-lockdown period. Multivariate LCM indicated the growth trajectory for novelty seeking was associated with the growth trajectories for stress, anxiety, and depression. This suggests that the observed decreases in stress, anxiety, and depression during the lockdown period may be attributable to the sample’s observed increase in novelty seeking. These findings are valuable in that they challenge the notion that lockdown measures are inherently detrimental to mental health. The findings indicate the important role of novelty seeking in responding to crises. It may be possible for future public health measures to incorporate the promotion of novelty seeking to help individuals’ respond to stressful situations and maintain good mental health in the face of crises. (shrink)

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Corporate social responsibility movement against labor abuses has gained momentum globally since the 1990s when many corporations adopted codes of conduct to regulate labor practices in their global supply chains. However, workers' participation in the process is relatively weak until very recently, when new worker empowerment programs are increasingly initiated. Using conceptual tool created by stakeholder theorists, this article examines dynamics and performance of worker participation in implementation process of codes of conduct through a case study of CSR practices of (...) Reebok at one of its footwear supplier factories in south China. Empirical data was collected during 2002-2005 through participant observation, in-depth interviews, and document reviews. (shrink)

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Faith and religious life in Islam; Islamic education and ethics.

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Background: Physical exercises can affect executive function both acutely and chronically, with different mechanisms for each moment. Currently, only a few reviews have elaborated on the premise that different types of exercises have different mechanisms for improving executive function. Therefore, the primary purpose of our systematic review was to analyze the effects of acute and chronic exercises on executive function in children and adolescents.Objective: We identified acute and chronic exercise studies and randomized controlled trials of executive function in children and (...) adolescents that reported overall effect, heterogeneity, and publication bias of acute and chronic exercises on executive function.Methods: We searched for RCTs of exercise interventions in children and adolescents from databases including PubMed, Web of Science, Scopus, The Cochrane Library, CNKI, and Wanfang, from January 1 2009 to December 31 2019. We performed methodological quality evaluations on the included literature using the Physiotherapy Evidence Database Scale and graded evidence with a meta-analysis using Stata 12.0 software.Results: In total, 36 RCTs were included ; the overall results of the meta-analysis indicated that acute exercises significantly improved working memory = −0.72; 95% confidence interval −0.89 to −0.56; p< 0.001), inhibitory control, and cognitive flexibility, whereas chronic exercises significantly improved working memory, inhibitory control, and cognitive flexibility.Conclusion: Acute and chronic exercises can effectively improve the executive function of children and adolescents. The effects on inhibitory control and cognitive flexibility are considered as small effect sizes, while the effects on working memory are considered as moderate effect size. Limited by the quantity and quality of the included studies, the above conclusions need to be verified with more high-quality studies. (shrink)

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This article examines how modern Chinese Buddhism has been influenced by Christianity. For our purposes ‘modern Chinese Buddhism’ refers to a form of what has become known in the West as ‘Engaged Buddhism’, but in Chinese is known by titles which can be translated ‘Humanistic Buddhism’ or ‘Buddhism for Human Life’. This tradition was initiated on the Chinese mainland between the two World Wars by the monk Tài X?, and Part one of the article is devoted to him. Since the (...) communist conquest of China, its main branches have flourished in Taiwan, whence two of them have spread worldwide. The most successful, at least in numerical terms, has been Fo Guang Shan, founded by a personal disciple of Tài X?, Hsing Yun, now very old, and it is on this movement that we concentrate in Parts two and three. We differentiate between conscious imitation and analogous development due to similar social circumstances, and show how Protestant Christianity and Roman Catholicism have had different effects. In Part four, we examine Fo Guang Shan as a missionary religion. (shrink)

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Large-screen human-computer interaction technology is reflected in all aspects of daily life. The dynamic gesture tracking algorithm commonly used in recent large-screen interactive technologies demonstrates compelling results but suffers from accuracy and real-time problems. This paper systematically addresses these issues by a switching federated filter method that combines particle filtering and Mean Shifting algorithms based on a 3D sensor. Compared with several algorithms, the results show that the one-hand and two-hand large-screen gesture tracking based on the switched federated filtering algorithm (...) work well, and there is no tracking failure and loss of target. Therefore, the switching federated tracking positioning algorithm can be well applied to the design of human-computer interaction system and provide new ideas for future human-computer interaction. (shrink)

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To demonstrate how green innovation effectively occurs, this study examines the effects of green intellectual capital on GI from the perspective of green supply chain integration. Based on a natural-resource-based view and knowledge-based view, the authors constructed an intermediary model of GIC-GSCI-GI, and analyzed the effects of green absorptive ability and relationship learning ability as moderators. An empirical survey of 328 Chinese manufacturing companies was conducted. Our results indicate that three dimensions of GIC positively impact GI. The mediating effects of (...) internal and external GSCI exist in the relationship between GIC and GI. The moderating effects of GAA and RLA in these effects were also verified. Our study provides further empirical evidence for the relationship between GIC and GI, highlights the effects of companies’ internal and external abilities on GI, and suggests new ways and implementation contexts for GI. (shrink)

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To add to the currently limited research on the degree of cultural uniqueness of Chinese EFL learners’ anxiety and the multidimensional nature of second language writing anxiety (SLWA), the present qualitative study used think-aloud protocol and interview to examine Chinese EFL learners’ three dimensions of SLWA and the related variables, so as to probe into this problem that could pose an obstacle to sustainable second language writing. Findings showed that Chinese EFL learners experienced much Cognitive Anxiety, but relatively little Avoidance (...) Behavior. Learner-internal, teacher-related, and human-external variables interacted with SLWA in a dynamic way. To a certain degree, Chinese EFL learners showcased uniqueness in some aspects of SLWA, under cultural influences, regarding ethnic culture, local culture, academic culture, and disciplinary culture. (shrink)

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Perceptual tasks such as object matching, mammogram interpretation, mental rotation, and satellite imagery change detection often require the assignment of correspondences to fuse information across views. We apply techniques developed for machine translation to the gaze data recorded from a complex perceptual matching task modeled after fingerprint examinations. The gaze data provide temporal sequences that the machine translation algorithm uses to estimate the subjects' assumptions of corresponding regions. Our results show that experts and novices have similar surface behavior, such as (...) the number of fixations made or the duration of fixations. However, the approach applied to data from experts is able to identify more corresponding areas between two prints. The fixations that are associated with clusters that map with high probability to corresponding locations on the other print are likely to have greater utility in a visual matching task. These techniques address a fundamental problem in eye tracking research with perceptual matching tasks: Given that the eyes always point somewhere, which fixations are the most informative and therefore are likely to be relevant for the comparison task? (shrink)

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Nelson Goodman (1906-2007) approached the arts and other kinds of knowledge as forms of symbolism. His principal aim in philosophy was to advance understanding and remove confusions by verbal analysis and logical constructions. Goodman's philosophical theories encompass nominalism, constructivism and a version of radical relativism. In his Languages of Art, Goodman sets forth distinctions among the various art according to differences in the forms of symbols employed. He contributed as well to arts education and to philosophy of the museum. His (...) performance work, "Hockey Seen: A Nightmare in Three Periods and Sudden Death embodies his aesthetic theories. (shrink)

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This paper examines the elusive concept of Xu in Zhuangzi’s philosophy to find out how specifically Xu addresses relationality through its distinct cultivation of ambiguity in this Daoist philosopher’s theory. The paper chooses liubai and body as two examples to unravel the ways in which the concept of Xu is manifested. Embedded in the meanings of blandness and lack of substance, Xu enlivens change, transformation and process. Evident in liubai, Xu creates a unique ecological space of metamorphosis that nourishes mutual (...) becoming. For Zhuangzi, body is neither understood as the object to be acquired nor as the means to acquire knowledge. Rather, body is a void to become. The political implication of Xu suggests a politics of indeterminacy – an alienation from preordained power structures and a reconstruction of power relations. (shrink)

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Ontological realism aims at the development of high quality ontologies that faithfully represent what is general in reality and to use these ontologies to render heterogeneous data collections comparable. To achieve this second goal for clinical research datasets presupposes not merely (1) that the requisite ontologies already exist, but also (2) that the datasets in question are faithful to reality in the dual sense that (a) they denote only particulars and relationships between particulars that do in fact exist and (b) (...) they do this in terms of the types and type-level relationships described in these ontologies. While much attention has been devoted to (1), work on (2), which is the topic of this paper, is comparatively rare. Using Referent Tracking as basis, we describe a technical data wrangling strategy which consists in creating for each dataset a template that, when applied to each particular record in the dataset, leads to the generation of a collection of Referent Tracking Tuples (RTT) built out of unique identifiers for the entities described by means of the data items in the record. The proposed strategy is based on (i) the distinction between data and what data are about, and (ii) the explicit descriptions of portions of reality which RTTs provide and which range not only over the particulars described by data items in a dataset, but also over these data items themselves. This last feature allows us to describe particulars that are only implicitly referred to by the dataset; to provide information about correspondences between data items in a dataset; and to assert which data items are unjustifiably or redundantly present in or absent from the dataset. The approach has been tested on a dataset collected from patients seeking treatment for orofacial pain at two German universities and made available for the NIDCR-funded OPMQoL project. (shrink)

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Motivated by Hoff and Stiglitz’s :753–763, 2004) theory, we examine empirically how the creation of “rules of the game” affect the behavior of economic agents in a transition economy. Using a sample of Chinese state-owned enterprises in which controlling ownership was transferred to private acquirers between 1994 and 2006, we find that the post-privatization performance of firms depends on institutional factors. Before 2003, we observe severe post-privatization tunneling behaviors by acquirers and worse PPP. However, from 2003, when the State issued (...) regulations against tunneling and strengthened enforcement, the incidence of tunneling behaviors declined, and PPP improved. We find that better implementation of ownership transfer and longer prior experience of private acquirers are key factors that contribute to the improvement. (shrink)

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Senior executives in major corporations have drawn attention in recent years for a range of unethical activities. Despite a rise in measures to protect against such lapses, executives still make decisions whether or not to comply with reporting standards, best practices, industry norms and legislation. The prior literature in this area addresses individual characteristics of decision makers and social networks between executives and boards of directors, but to this point has largely overlooked group dynamics of the executive team. Our study (...) addresses this gap and examines the relationship between an occupational community of top executives and the quality of internal control. We construct a unique measure for the executive occupational community based on CEO and CFO’s joint tenure. Our findings show that the number of years of CEO/cfo’s joint tenure is significantly and negatively associated with internal control weakness, suggesting that the longer the executive relationship, the lower the likelihood of internal control weakness. Our study indicates that the presence of an occupational community contributes to better internal control. (shrink)

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The utilisation of human organoids has the potential to expedite the cycle of biological innovation significantly, yet it also raises a series of ethical and societal concerns. This study aims to evaluate the perceptions and attitudes of researchers regarding the ethical and social challenges associated with the research and application of human organoids. A 20-item questionnaire was developed to assess various aspects: four items evaluated the overall understanding of organoids, 13 items addressed ontological, ownership, informed consent and additional ethical issues, (...) while the remaining four items focused on ethical governance and regulatory concerns. This questionnaire was distributed to attendees of the 3rd China Symposium on 3D Cell Culture and Organoids in May 2023. Basic descriptive statistical analyses and chi-square tests were conducted. The work has been reported in line with the ARRIVE guidelines 2.0. A substantial majority (over 70%) of participants expressed concerns that the research and application of human organoids might raise ethical issues, such as moral status, informed consent and commercialisation. In contrast, a minor segment (4.5%, n = 8) reported feelings of disgust or nausea towards human-animal neural chimeras, with a significant gender difference (p = 0.004). Regarding informed consent for human organoid samples, over 90% of researchers rejected blanket consent for all purposes, and more than half preferred a model of continuous consent, which entails resoliciting consent for new uses. Further, over 40% of participants believed that the commercialisation of human organoids is dependent on their specific type. Our findings show that some researchers held that as long as human embryonic stem cells are not utilised in human organoid research and application, there are no ethical relevant issues. Most researchers also showed indifference towards the concern of moral status and humanisation of animals. The majority believe that the “consent for governance” model is preferable than broad consent or specific consent. We believe to realise the promise of human organoids for medicine, navigating complex ethics tensions and proactively engaging diverse stakeholders are required. Only with prudent, thoughtful and effective guidance, mutual understanding and trust between scientists and public can be fostered; the promising field of organoids can progress rapidly and responsibly. (shrink)

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