Movatterモバイル変換


[0]ホーム

URL:


PhilPapersPhilPeoplePhilArchivePhilEventsPhilJobs
Switch to: References

Add citations

You mustlogin to add citations.
  1. Ins and outs of systems biology vis-à-vis molecular biology: Continuation or clear cut?Philippe De Backer,Danny De Waele &Linda Van Speybroeck -2009 -Acta Biotheoretica 58 (1):15-49.
    The comprehension of living organisms in all their complexity poses a major challenge to the biological sciences. Recently, systems biology has been proposed as a new candidate in the development of such a comprehension. The main objective of this paper is to address what systems biology is and how it is practised. To this end, the basic tools of a systems biological approach are explored and illustrated. In addition, it is questioned whether systems biology ‘revolutionizes’ molecular biology and ‘transcends’ its (...) assumed reductionism. The strength of this claim appears to depend on how molecular and systems biology are characterised and on how reductionism is interpreted. Doing credit to molecular biology and to methodological reductionism, it is argued that the distinction between molecular and systems biology is gradual rather than sharp. As such, the classical challenge in biology to manage, interpret and integrate biological data into functional wholes is further intensified by systems biology’s use of modelling and bioinformatics, and by its scale enlargement. (shrink)
    Direct download(2 more)  
     
    Export citation  
     
    Bookmark   10 citations  
  • Dependence relationships between Gene Ontology terms based on TIGR gene product annotations.Anand Kumar,Barry Smith &Christian Borgelt -2004 -Proceedings of the 3rd International Workshop on Computational Terminology 2004:31-38.
    The Gene Ontology is an important tool for the representation and processing of information about gene products and functions. It provides controlled vocabularies for the designations of cellular components, molecular functions, and biological processes used in the annotation of genes and gene products. These constitute three separate ontologies, of cellular components), molecular functions and biological processes, respectively. The question we address here is: how are the terms in these three separate ontologies related to each other? We use statistical methods and (...) formal ontological principles as a first step towards finding answers to this question. (shrink)
    Direct download  
     
    Export citation  
     
    Bookmark   2 citations  

  • [8]ページ先頭

    ©2009-2025 Movatter.jp