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Inman et al., 2018 - Google Patents

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature

Inman et al., 2018

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Document ID
15970619463944800754
Author
Inman G
Wang J
Nagano A
Alexandrov L
Purdie K
Taylor R
Sherwood V
Thomson J
Hogan S
Spender L
South A
Stratton M
Chelala C
Harwood C
Proby C
Leigh I
Publication year
Publication venue
Nature communications

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Cutaneous squamous cell carcinoma (cSCC) has a high tumour mutational burden (50 mutations per megabase DNA pair). Here, we combine whole-exome analyses from 40 primary cSCC tumours, comprising 20 well-differentiated and 20 moderately/poorly …
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