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WO2007132207A3 - Process for cross-linking moieties - Google Patents

Process for cross-linking moieties
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Publication number
WO2007132207A3
WO2007132207A3PCT/GB2007/001745GB2007001745WWO2007132207A3WO 2007132207 A3WO2007132207 A3WO 2007132207A3GB 2007001745 WGB2007001745 WGB 2007001745WWO 2007132207 A3WO2007132207 A3WO 2007132207A3
Authority
WO
WIPO (PCT)
Prior art keywords
cross
linking moieties
moiety
linking
linker
Prior art date
Application number
PCT/GB2007/001745
Other languages
French (fr)
Other versions
WO2007132207A2 (en
Inventor
Graham Mock
Original Assignee
Graham Mock
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Graham MockfiledCriticalGraham Mock
Publication of WO2007132207A2publicationCriticalpatent/WO2007132207A2/en
Publication of WO2007132207A3publicationCriticalpatent/WO2007132207A3/en

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Abstract

The invention relates to a process for linking a first moiety with a linker and to cross-linking a first moiety such as a nucleic acid or protein with a second moiety such as an antibody or enzyme. In preferred embodiments of the invention, the linker is diisothiocyanatostilbenedisulphonic acid (DIDS) or a dimer thereof.
PCT/GB2007/0017452006-05-112007-05-11Process for cross-linking moietiesWO2007132207A2 (en)

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
GBGB0609370.2AGB0609370D0 (en)2006-05-112006-05-11Process for cross-linking macromolecules
GB0609370.22006-05-11

Publications (2)

Publication NumberPublication Date
WO2007132207A2 WO2007132207A2 (en)2007-11-22
WO2007132207A3true WO2007132207A3 (en)2008-08-21

Family

ID=36637328

Family Applications (1)

Application NumberTitlePriority DateFiling Date
PCT/GB2007/001745WO2007132207A2 (en)2006-05-112007-05-11Process for cross-linking moieties

Country Status (2)

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GB (2)GB0609370D0 (en)
WO (1)WO2007132207A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
GB201615466D0 (en)*2016-09-122016-10-26Gfc Diagnostics LtdMethod for detecting bacteria

Citations (4)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
EP0398024A1 (en)*1989-04-191990-11-22Deutsches Krebsforschungszentrum Stiftung des öffentlichen RechtsConjugates for tumor localization and/or tumortherapy
EP0584794A2 (en)*1992-08-251994-03-02Yissum Research Development Company Of The Hebrew University Of JerusalemElectrobiochemical analytical method and electrodes
US5532129A (en)*1991-11-071996-07-02Enterprise Partners Ii, L.P.Self-organizing molecular photonic structures based on chromophore- and fluorophore-containing polynucleotides and methods of their use
US6241863B1 (en)*1998-04-272001-06-05Harold G. MonbouquetteAmperometric biosensors based on redox enzymes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
JP4007000B2 (en)*2001-12-252007-11-14富士ゼロックス株式会社 Conductive organic polymer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
EP0398024A1 (en)*1989-04-191990-11-22Deutsches Krebsforschungszentrum Stiftung des öffentlichen RechtsConjugates for tumor localization and/or tumortherapy
US5532129A (en)*1991-11-071996-07-02Enterprise Partners Ii, L.P.Self-organizing molecular photonic structures based on chromophore- and fluorophore-containing polynucleotides and methods of their use
EP0584794A2 (en)*1992-08-251994-03-02Yissum Research Development Company Of The Hebrew University Of JerusalemElectrobiochemical analytical method and electrodes
US6241863B1 (en)*1998-04-272001-06-05Harold G. MonbouquetteAmperometric biosensors based on redox enzymes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HUA S. ET AL.: "Lys515-Lys492 Cross-linking by DIDS Interferes with substrate Utilization by the Sarcoplasmic reticulum ATPase", BIOPHYSICAL JOURNAL, vol. 73, 1997, pages 2149 - 2155, XP007904540*
KAVANAUGH ET AL.: "Affinity labeling of hemoglobin with 4,4'-Diisothiocyanostilbene-2,2'-disulfonate: covalent cross-linking in the 2, 3-diphosphoglycerate binding site", BIOCHEMISTRY, vol. 27, 1988, pages 1804 - 1808, XP007904541*

Also Published As

Publication numberPublication date
GB2438088A (en)2007-11-14
GB2438088B (en)2010-04-28
GB0709127D0 (en)2007-06-20
WO2007132207A2 (en)2007-11-22
GB0609370D0 (en)2006-06-21

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