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WO2007025304A3 - Process for preparing saccharinic acids and lactones - Google Patents

Process for preparing saccharinic acids and lactonesDownload PDF

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Publication number
WO2007025304A3
WO2007025304A3PCT/US2006/033736US2006033736WWO2007025304A3WO 2007025304 A3WO2007025304 A3WO 2007025304A3US 2006033736 WUS2006033736 WUS 2006033736WWO 2007025304 A3WO2007025304 A3WO 2007025304A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparing
lactones
utilizes
saccharinic acids
saccharinic
Prior art date
Application number
PCT/US2006/033736
Other languages
French (fr)
Other versions
WO2007025304A2 (en
Inventor
David Hotchkiss
George Fleet
Thomas Heinz
Richard Storer
Original Assignee
Chancellors Masters And Schola
Idenix Pharmaceuticals Inc
Novartis Ag
David Hotchkiss
George Fleet
Thomas Heinz
Richard Storer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chancellors Masters And Schola, Idenix Pharmaceuticals Inc, Novartis Ag, David Hotchkiss, George Fleet, Thomas Heinz, Richard StorerfiledCriticalChancellors Masters And Schola
Publication of WO2007025304A2publicationCriticalpatent/WO2007025304A2/en
Publication of WO2007025304A3publicationCriticalpatent/WO2007025304A3/en

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Abstract

An improved process for preparing a saccharinic acid or lactone is disclosed that utilizes the well-known Amadori rearrangement reaction. The synthesis utilizes protected or unprotected sugars or their analogues as starting materials, and reagents not previously utilized to afford increased product yields in decreased reaction time.
PCT/US2006/0337362005-08-262006-08-28Process for preparing saccharinic acids and lactonesWO2007025304A2 (en)

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
US71193405P2005-08-262005-08-26
US60/711,9342005-08-26

Publications (2)

Publication NumberPublication Date
WO2007025304A2 WO2007025304A2 (en)2007-03-01
WO2007025304A3true WO2007025304A3 (en)2007-05-31

Family

ID=37772543

Family Applications (1)

Application NumberTitlePriority DateFiling Date
PCT/US2006/033736WO2007025304A2 (en)2005-08-262006-08-28Process for preparing saccharinic acids and lactones

Country Status (3)

CountryLink
AR (1)AR057096A1 (en)
UY (1)UY29769A1 (en)
WO (1)WO2007025304A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US7456155B2 (en)2002-06-282008-11-25Idenix Pharmaceuticals, Inc.2′-C-methyl-3′-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
US7582618B2 (en)2002-06-282009-09-01Idenix Pharmaceuticals, Inc.2′-C-methyl-3′-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
US7598373B2 (en)2002-12-122009-10-06Idenix Pharmaceuticals, Inc.Process for the production of 2-C-methyl-D-ribonolactone
US7608597B2 (en)2000-05-232009-10-27Idenix Pharmaceuticals, Inc.Methods and compositions for treating hepatitis C virus

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
EA007867B1 (en)2000-05-262007-02-27Айденикс (Кайман) ЛимитедMethods and compositions for treating flaviviruses and pestiviruses
CA2506129C (en)2002-11-152015-02-17Idenix (Cayman) Limited2'-branched nucleosides and flaviviridae mutation
JP5342887B2 (en)*2009-01-292013-11-13花王株式会社 Method for producing α-aminoketone compound
KR20150028808A (en)2012-06-132015-03-16브리스톨-마이어스 스큅 컴퍼니Process for the preparation of 2-c-methyl-d-ribonic-gamma-lactone
CN104693158B (en)*2015-02-152017-03-29上海应用技术学院A kind of method for preparing 2 C methyl D ribonic acids, 1,4 lactone
CN104693157A (en)*2015-02-152015-06-10上海应用技术学院Preparation method of 2-C-methyl-D-ribotide-1,4-lactone

Citations (1)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US6891036B2 (en)*2003-02-102005-05-10Inalco S.P.A.Process for the preparation of ribofuranose derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US6891036B2 (en)*2003-02-102005-05-10Inalco S.P.A.Process for the preparation of ribofuranose derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KUHN R. ET AL: "Uber eine molekulare Umlagerung von N-glucosiden", BERICHTE, vol. 69B, 1936, pages 1745 - 1754, XP008081654*

Cited By (5)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US7608597B2 (en)2000-05-232009-10-27Idenix Pharmaceuticals, Inc.Methods and compositions for treating hepatitis C virus
US8299038B2 (en)2000-05-232012-10-30Idenix Pharmaceuticals, Inc.Methods and compositions for treating hepatitis C virus
US7456155B2 (en)2002-06-282008-11-25Idenix Pharmaceuticals, Inc.2′-C-methyl-3′-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
US7582618B2 (en)2002-06-282009-09-01Idenix Pharmaceuticals, Inc.2′-C-methyl-3′-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
US7598373B2 (en)2002-12-122009-10-06Idenix Pharmaceuticals, Inc.Process for the production of 2-C-methyl-D-ribonolactone

Also Published As

Publication numberPublication date
UY29769A1 (en)2007-02-28
WO2007025304A2 (en)2007-03-01
AR057096A1 (en)2007-11-14

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