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WO2005097186A3 - Bioactive stents for type ii diabetics and methods for use thereof - Google Patents

Bioactive stents for type ii diabetics and methods for use thereofDownload PDF

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Publication number
WO2005097186A3
WO2005097186A3PCT/US2005/011231US2005011231WWO2005097186A3WO 2005097186 A3WO2005097186 A3WO 2005097186A3US 2005011231 WUS2005011231 WUS 2005011231WWO 2005097186 A3WO2005097186 A3WO 2005097186A3
Authority
WO
WIPO (PCT)
Prior art keywords
diabetics
type
vascular
bioligand
pecs
Prior art date
Application number
PCT/US2005/011231
Other languages
French (fr)
Other versions
WO2005097186A2 (en
Inventor
Kenneth W Carpenter
William G Turnell
Kristen M Defife
Kathryn A Grako
Original Assignee
Medivas Llc
Kenneth W Carpenter
William G Turnell
Kristen M Defife
Kathryn A Grako
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivas Llc, Kenneth W Carpenter, William G Turnell, Kristen M Defife, Kathryn A GrakofiledCriticalMedivas Llc
Priority to JP2007507391ApriorityCriticalpatent/JP2007532185A/en
Priority to CN200580015085XAprioritypatent/CN1984620B/en
Priority to AU2005231458Aprioritypatent/AU2005231458A1/en
Priority to EP05767563Aprioritypatent/EP1737379A4/en
Priority to CA002562018Aprioritypatent/CA2562018A1/en
Publication of WO2005097186A2publicationCriticalpatent/WO2005097186A2/en
Publication of WO2005097186A3publicationCriticalpatent/WO2005097186A3/en

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Abstract

The present invention is based on the discovery that a vascular stent or other implantable medical device can be coated with a biodegradable biocompatible polymer to which is attached a bioligand that specifically captures progenitors of endothelial cells (PECs) from the circulating blood to promote endogenous formation of healthy endothelium in Type II diabetics. In one embodiment, the bioligand is a peptide that specifically binds to an integrin receptor on PECs. The invention also provides methods for using such vascular stents and other implantable devices to promote vascular healing in Type II diabetics, for example following mechanical intervention.
PCT/US2005/0112312004-04-052005-04-04Bioactive stents for type ii diabetics and methods for use thereofWO2005097186A2 (en)

Priority Applications (5)

Application NumberPriority DateFiling DateTitle
JP2007507391AJP2007532185A (en)2004-04-052005-04-04 Bioactive stent for type II diabetes and method of use thereof
CN200580015085XACN1984620B (en)2004-04-052005-04-04Bioactive bracket for type II diabetics
AU2005231458AAU2005231458A1 (en)2004-04-052005-04-04Bioactive stents for type II diabetics and methods for use thereof
EP05767563AEP1737379A4 (en)2004-04-052005-04-04Bioactive stents for type ii diabetics and methods for use thereof
CA002562018ACA2562018A1 (en)2004-04-052005-04-04Bioactive stents for type ii diabetics and methods for use thereof

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
US55993704P2004-04-052004-04-05
US60/559,9372004-04-05

Publications (2)

Publication NumberPublication Date
WO2005097186A2 WO2005097186A2 (en)2005-10-20
WO2005097186A3true WO2005097186A3 (en)2006-09-14

Family

ID=35125623

Family Applications (1)

Application NumberTitlePriority DateFiling Date
PCT/US2005/011231WO2005097186A2 (en)2004-04-052005-04-04Bioactive stents for type ii diabetics and methods for use thereof

Country Status (6)

CountryLink
EP (1)EP1737379A4 (en)
JP (1)JP2007532185A (en)
CN (1)CN1984620B (en)
AU (1)AU2005231458A1 (en)
CA (1)CA2562018A1 (en)
WO (1)WO2005097186A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
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US8652504B2 (en)2005-09-222014-02-18Medivas, LlcSolid polymer delivery compositions and methods for use thereof
US9102830B2 (en)2005-09-222015-08-11Medivas, LlcBis-(α-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use
US9517203B2 (en)2000-08-302016-12-13Mediv As, LlcPolymer particle delivery compositions and methods of use

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US20060271168A1 (en)*2002-10-302006-11-30Klaus KleineDegradable medical device
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US8163269B2 (en)*2004-04-052012-04-24Carpenter Kenneth WBioactive stents for type II diabetics and methods for use thereof
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US20070282011A1 (en)*2006-05-092007-12-06Medivas, LlcBiodegradable water soluble polymers
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WO2009011938A1 (en)*2007-07-172009-01-22Medivas, LlcBioabsorbable elastomeric arterial support device and methods of use
US20090074831A1 (en)*2007-09-182009-03-19Robert FaloticoLOCAL VASCULAR DELIVERY OF mTOR INHIBITORS IN COMBINATION WITH PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR STIMULATORS
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CN101879102B (en)*2009-05-072014-07-09上海微创医疗器械（集团）有限公司Groove carrying-type coating decomposable drug eluting stent
WO2011045443A1 (en)*2009-10-162011-04-21Dsm Ip Assets B.V.Coatings comprising bis-(alpha-amino-diol-diester) containing polyesteramide
US9873765B2 (en)2011-06-232018-01-23Dsm Ip Assets, B.V.Biodegradable polyesteramide copolymers for drug delivery
US9873764B2 (en)2011-06-232018-01-23Dsm Ip Assets, B.V.Particles comprising polyesteramide copolymers for drug delivery
US20140220017A1 (en)2011-09-232014-08-07Universitat StuttgartSerum half-life extension using igbd
US9220759B2 (en)2012-02-232015-12-29Abbott Cardiovascular Systems Inc.Treatment of diabetic patients with a drug eluting stent and adjunctive therapy
US9220584B2 (en)2012-03-302015-12-29Abbott Cardiovascular Systems Inc.Treatment of diabetic patients with a stent and locally administered adjunctive therapy
US20150328374A1 (en)*2012-12-202015-11-19Dsm Ip Assets B.V.Coating comprising polyesteramide copolymers for drug delivery
US10434071B2 (en)2014-12-182019-10-08Dsm Ip Assets, B.V.Drug delivery system for delivery of acid sensitivity drugs
EP4069327A1 (en)*2019-12-042022-10-12Cortronik GmbHSwellable polymer hybrid fibres for a sleeve of an intraluminal endoprosthesis

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US20030064053A1 (en)*2001-08-312003-04-03Shengjiang LiuMultivalent protein conjugate with multiple ligand-binding domains of receptors

Non-Patent Citations (1)

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See also references ofEP1737379A4*

Cited By (3)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US9517203B2 (en)2000-08-302016-12-13Mediv As, LlcPolymer particle delivery compositions and methods of use
US8652504B2 (en)2005-09-222014-02-18Medivas, LlcSolid polymer delivery compositions and methods for use thereof
US9102830B2 (en)2005-09-222015-08-11Medivas, LlcBis-(α-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use

Also Published As

Publication numberPublication date
CN1984620A (en)2007-06-20
CA2562018A1 (en)2005-10-20
CN1984620B (en)2011-03-30
WO2005097186A2 (en)2005-10-20
JP2007532185A (en)2007-11-15
AU2005231458A1 (en)2005-10-20
EP1737379A2 (en)2007-01-03
EP1737379A4 (en)2011-08-17

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