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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| US8168389B2 (en) | 2006-06-14 | 2012-05-01 | The General Hospital Corporation | Fetal cell analysis using sample splitting |
| US8195415B2 (en) | 2008-09-20 | 2012-06-05 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US10591391B2 (en) | 2006-06-14 | 2020-03-17 | Verinata Health, Inc. | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| US10704090B2 (en) | 2006-06-14 | 2020-07-07 | Verinata Health, Inc. | Fetal aneuploidy detection by sequencing |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6913697B2 (en) | 2001-02-14 | 2005-07-05 | Science & Technology Corporation @ Unm | Nanostructured separation and analysis devices for biological membranes |
| US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
| US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
| AU2003216175A1 (en) | 2002-02-04 | 2003-09-02 | Colorado School Of Mines | Laminar flow-based separations of colloidal and cellular particles |
| CA2500392C (en) | 2002-09-27 | 2012-11-27 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
| EP1678327A4 (en)* | 2003-10-16 | 2007-10-10 | Genomic Health Inc | Qrt-pcr assay system for gene expression profiling |
| US7332597B2 (en) | 2004-06-28 | 2008-02-19 | University Of Kentucky Research Foundation | Primers and probe to identify mycobacterium tuberculosis complex |
| ITBO20040420A1 (en) | 2004-07-07 | 2004-10-07 | Type S R L | METAL CUTTING AND FORMING MACHINE |
| DE102005013261A1 (en)* | 2005-03-22 | 2006-09-28 | Adnagen Ag | Reagent and method for preventing time-dependent expression in biological cells |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| DE102005029808A1 (en)* | 2005-06-27 | 2007-01-04 | Siemens Ag | Support material, process for its preparation and use |
| ITBO20050481A1 (en) | 2005-07-19 | 2007-01-20 | Silicon Biosystems S R L | METHOD AND APPARATUS FOR THE HANDLING AND / OR IDENTIFICATION OF PARTICLES |
| EP1930426A4 (en) | 2005-09-02 | 2009-04-29 | Toray Industries | COMPOSITION AND METHOD FOR DIAGNOSIS OF KIDNEY CANCER AND EVALUATION OF VITAL PROGNOSIS OF A PATIENT WITH KIDNEY CANCER |
| US20070059683A1 (en)* | 2005-09-15 | 2007-03-15 | Tom Barber | Veterinary diagnostic system |
| ES2886923T3 (en) | 2005-09-20 | 2021-12-21 | Menarini Silicon Biosystems Spa | Methods and composition for generating single-sequence DNA probes, labeling of DNA probes, and the use of these probes |
| US9134237B2 (en) | 2005-09-20 | 2015-09-15 | Janssen Diagnotics, LLC | High sensitivity multiparameter method for rare event analysis in a biological sample |
| ITBO20050646A1 (en) | 2005-10-26 | 2007-04-27 | Silicon Biosystem S R L | METHOD AND APPARATUS FOR CHARACTERIZATION AND COUNTING OF PARTICLES |
| US8119976B2 (en) | 2007-07-03 | 2012-02-21 | Colorado School Of Mines | Optical-based cell deformability |
| US9885644B2 (en) | 2006-01-10 | 2018-02-06 | Colorado School Of Mines | Dynamic viscoelasticity as a rapid single-cell biomarker |
| US9878326B2 (en) | 2007-09-26 | 2018-01-30 | Colorado School Of Mines | Fiber-focused diode-bar optical trapping for microfluidic manipulation |
| US9487812B2 (en) | 2012-02-17 | 2016-11-08 | Colorado School Of Mines | Optical alignment deformation spectroscopy |
| ITTO20060226A1 (en) | 2006-03-27 | 2007-09-28 | Silicon Biosystem S P A | METHOD AND APPARATUS FOR PROCESSING AND OR ANALYSIS AND OR SELECTION OF PARTICLES, IN PARTICULAR BIOLOGICAL PARTICLES |
| EP2008102A4 (en)* | 2006-04-18 | 2009-07-08 | Wellstat Biologics Corp | Detection of proteins from circulating neoplastic cells |
| CN101583722A (en) | 2006-07-14 | 2009-11-18 | 阿维瓦生物科学股份有限公司 | Methods and compositions for detecting rare cells from a biological sample |
| JP4926812B2 (en)* | 2007-02-01 | 2012-05-09 | シスメックス株式会社 | Blood cell analyzer and body fluid analysis method |
| US10722250B2 (en) | 2007-09-04 | 2020-07-28 | Colorado School Of Mines | Magnetic-field driven colloidal microbots, methods for forming and using the same |
| ITTO20070771A1 (en) | 2007-10-29 | 2009-04-30 | Silicon Biosystems Spa | METHOD AND APPARATUS FOR IDENTIFICATION AND HANDLING OF PARTICLES |
| IT1391619B1 (en) | 2008-11-04 | 2012-01-11 | Silicon Biosystems Spa | METHOD FOR THE IDENTIFICATION, SELECTION AND ANALYSIS OF TUMOR CELLS |
| US10895575B2 (en) | 2008-11-04 | 2021-01-19 | Menarini Silicon Biosystems S.P.A. | Method for identification, selection and analysis of tumour cells |
| KR101936842B1 (en) | 2009-03-17 | 2019-01-10 | 메나리니 실리콘 바이오시스템스 에스.피.에이. | Microfluidic device for isolation of cells |
| JP5729904B2 (en) | 2009-06-02 | 2015-06-03 | キヤノン株式会社 | Methods for preparing proteins, DNA, RNA from cells |
| CN102575244B (en) | 2009-09-17 | 2015-07-22 | Jsr株式会社 | Dissociation method and dissociation agent of avidin and biotin derivative |
| CN102803490B (en)* | 2010-01-04 | 2015-03-25 | 奇亚根盖瑟斯堡股份有限公司 | Methods, compositions and kits for the recovery of nucleic acids or proteins from fixed tissue samples |
| WO2012034013A2 (en) | 2010-09-10 | 2012-03-15 | Bio-Rad Laboratories, Inc. | Detection of rna-interacting regions in dna |
| CN102565404B (en)* | 2010-12-24 | 2014-04-16 | 牛刚 | Kit for detecting free colorectal cancer cell markers in blood |
| CN102156164B (en)* | 2011-01-13 | 2012-12-12 | 北京肿瘤医院 | Mass spectra identification method of nucleophosmin variable spliceosome and gastric cancer diagnostic reagent kit |
| CN102109525B (en)* | 2011-01-26 | 2013-10-16 | 牛刚 | Kit for detecting free breast cancer cell marker in blood |
| EP2675913B1 (en) | 2011-02-15 | 2016-12-14 | Bio-Rad Laboratories, Inc. | Detecting methylation in a subpopulation of genomic dna |
| US20120252038A1 (en)* | 2011-04-01 | 2012-10-04 | Chianese David A | Steroid receptor assays |
| US8728987B2 (en)* | 2011-08-03 | 2014-05-20 | Bio-Rad Laboratories, Inc. | Filtering small nucleic acids using permeabilized cells |
| ITTO20110990A1 (en) | 2011-10-28 | 2013-04-29 | Silicon Biosystems Spa | METHOD AND APPARATUS FOR OPTICAL ANALYSIS OF LOW TEMPERATURE PARTICLES |
| ITBO20110766A1 (en) | 2011-12-28 | 2013-06-29 | Silicon Biosystems Spa | DEVICES, EQUIPMENT, KITS AND METHOD FOR THE TREATMENT OF A BIOLOGICAL SAMPLE |
| WO2014067528A1 (en)* | 2012-10-29 | 2014-05-08 | Arcedi Biotech Aps | Improved enrichment and detection of rare blood cells |
| WO2014145989A1 (en)* | 2013-03-15 | 2014-09-18 | Iris International, Inc. | Method and composition for staining and processing a urine sample |
| US9857361B2 (en) | 2013-03-15 | 2018-01-02 | Iris International, Inc. | Flowcell, sheath fluid, and autofocus systems and methods for particle analysis in urine samples |
| US9771571B2 (en) | 2014-02-28 | 2017-09-26 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| USRE48665E1 (en)* | 2014-02-28 | 2021-08-03 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| US9771572B2 (en) | 2014-02-28 | 2017-09-26 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| JP2014158468A (en)* | 2014-03-05 | 2014-09-04 | Clinical Genomics Pty Ltd | Detection method |
| WO2016130704A2 (en)* | 2015-02-10 | 2016-08-18 | Illumina, Inc. | Methods and compositions for analyzing cellular components |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| US10282588B2 (en)* | 2016-06-09 | 2019-05-07 | Siemens Healthcare Gmbh | Image-based tumor phenotyping with machine learning from synthetic data |
| CA3079415A1 (en) | 2017-10-19 | 2019-04-25 | Streck, Inc. | Compositions for hemolysis and coagulation regulation and stabilization of extracellular vesicles |
| CN110456034B (en)* | 2018-05-07 | 2022-07-22 | 上海市第十人民医院 | A kind of detection method of circulating tumor cells |
| CN109402240B (en)* | 2019-01-08 | 2020-08-25 | 圣湘生物科技股份有限公司 | Nucleic acid releasing agent, nucleic acid PCR amplification method and PCR amplification kit |
| WO2023080601A1 (en)* | 2021-11-05 | 2023-05-11 | 고려대학교 세종산학협력단 | Disease diagnosis method and device using machine learning-based lens-free shadow imaging technology |
| KR102707636B1 (en)* | 2021-11-05 | 2024-09-20 | 고려대학교 세종산학협력단 | Device and method of leukemia diagnosis using machine learning-based lens-free shadow imaging technology |
| JP2023103711A (en)* | 2022-01-14 | 2023-07-27 | 株式会社島津製作所 | Electrophoresis system, electrophoresis apparatus, electrophoresis analysis method, and electrophoresis analysis program |
| CN116042772B (en)* | 2023-02-10 | 2025-07-29 | 上海立闻生物科技有限公司 | Methods and kits for whole transcriptome sequencing of small amounts of tumor cells from fresh samples |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4929556A (en)* | 1986-02-06 | 1990-05-29 | The Dow Chemical Company | Enzyme immobilization with polysulfonium salts |
| US5346994A (en)* | 1992-01-28 | 1994-09-13 | Piotr Chomczynski | Shelf-stable product and process for isolating RNA, DNA and proteins |
| US6156564A (en)* | 1996-06-07 | 2000-12-05 | The United States Of America As Represented By The Department Of Health And Human Services | Cellular apoptosis susceptibility protein (CSP) and antisense CSP |
| US6329179B1 (en)* | 1996-03-26 | 2001-12-11 | Oncomedx, Inc. | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer |
| US6358697B2 (en)* | 1999-04-21 | 2002-03-19 | Children's Hospital Medical Center | Intracellular pharmaceutical targeting |
| US6365362B1 (en)* | 1998-02-12 | 2002-04-02 | Immunivest Corporation | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0951541B1 (en)* | 1995-07-31 | 2005-11-30 | Urocor, Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate disease |
| US6156515A (en)* | 1999-02-09 | 2000-12-05 | Urocor, Inc. | Prostate-specific gene for diagnosis, prognosis and management of prostate cancer |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4929556A (en)* | 1986-02-06 | 1990-05-29 | The Dow Chemical Company | Enzyme immobilization with polysulfonium salts |
| US5346994A (en)* | 1992-01-28 | 1994-09-13 | Piotr Chomczynski | Shelf-stable product and process for isolating RNA, DNA and proteins |
| US6329179B1 (en)* | 1996-03-26 | 2001-12-11 | Oncomedx, Inc. | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer |
| US6156564A (en)* | 1996-06-07 | 2000-12-05 | The United States Of America As Represented By The Department Of Health And Human Services | Cellular apoptosis susceptibility protein (CSP) and antisense CSP |
| US6365362B1 (en)* | 1998-02-12 | 2002-04-02 | Immunivest Corporation | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| US6358697B2 (en)* | 1999-04-21 | 2002-03-19 | Children's Hospital Medical Center | Intracellular pharmaceutical targeting |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11674176B2 (en) | 2006-06-14 | 2023-06-13 | Verinata Health, Inc | Fetal aneuploidy detection by sequencing |
| US9273355B2 (en) | 2006-06-14 | 2016-03-01 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
| US10591391B2 (en) | 2006-06-14 | 2020-03-17 | Verinata Health, Inc. | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| US8372584B2 (en) | 2006-06-14 | 2013-02-12 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| US8168389B2 (en) | 2006-06-14 | 2012-05-01 | The General Hospital Corporation | Fetal cell analysis using sample splitting |
| US9017942B2 (en) | 2006-06-14 | 2015-04-28 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
| US11781187B2 (en) | 2006-06-14 | 2023-10-10 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
| US9347100B2 (en) | 2006-06-14 | 2016-05-24 | Gpb Scientific, Llc | Rare cell analysis using sample splitting and DNA tags |
| US11261492B2 (en) | 2006-06-14 | 2022-03-01 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| US10704090B2 (en) | 2006-06-14 | 2020-07-07 | Verinata Health, Inc. | Fetal aneuploidy detection by sequencing |
| US10041119B2 (en) | 2006-06-14 | 2018-08-07 | Verinata Health, Inc. | Methods for the diagnosis of fetal abnormalities |
| US10155984B2 (en) | 2006-06-14 | 2018-12-18 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
| US10435751B2 (en) | 2006-06-14 | 2019-10-08 | Verinata Health, Inc. | Methods for the diagnosis of fetal abnormalities |
| US8682594B2 (en) | 2008-09-20 | 2014-03-25 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
| US10669585B2 (en) | 2008-09-20 | 2020-06-02 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
| US9404157B2 (en) | 2008-09-20 | 2016-08-02 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
| US9353414B2 (en) | 2008-09-20 | 2016-05-31 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
| US8296076B2 (en) | 2008-09-20 | 2012-10-23 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuoploidy by sequencing |
| US8195415B2 (en) | 2008-09-20 | 2012-06-05 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
| US12054777B2 (en) | 2008-09-20 | 2024-08-06 | The Board Of Trustees Of The Leland Standford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
| Publication number | Publication date |
|---|---|
| WO2003035895A2 (en) | 2003-05-01 |
| CA2465288A1 (en) | 2003-05-01 |
| JP2005507997A (en) | 2005-03-24 |
| AU2002360305A1 (en) | 2003-05-06 |
| EP1438398A2 (en) | 2004-07-21 |
| WO2003035894A2 (en) | 2003-05-01 |
| WO2003035894A8 (en) | 2004-06-03 |
| CN1610752A (en) | 2005-04-27 |
| BR0213520A (en) | 2006-05-23 |
| EP1438419A2 (en) | 2004-07-21 |
| CA2465274A1 (en) | 2003-05-01 |
| KR20040047971A (en) | 2004-06-05 |
| IL161357A0 (en) | 2004-09-27 |
| WO2003035895A3 (en) | 2004-01-08 |
| Publication | Publication Date | Title |
|---|---|---|
| WO2003035894A8 (en) | Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample | |
| US20230366034A1 (en) | Compositions and methods for diagnosing lung cancers using gene expression profiles | |
| Gläser et al. | Detection of circulating melanoma cells by specific amplification of tyrosinase complementary DNA is not a reliable tumor marker in melanoma patients: a clinical two-center study. | |
| EP1871912B1 (en) | Method for determining DNA methylation in blood or urine samples | |
| AU767983B2 (en) | Methods for detecting nucleic acids indicative of cancer | |
| CA2455731A1 (en) | Methods for evaluating pathologic conditions using extracellular rna | |
| JP7626797B2 (en) | Detection of microsatellite instability | |
| EP2357255A2 (en) | Assay for methylation in the GST-Pi gene | |
| WO2002079411A3 (en) | Microarray gene expression profiling in clear cell renal cell carcinoma: prognosis and drug target identification | |
| Takano et al. | Quantitative measurement of thyroglobulin mRNA in peripheral blood of patients after total thyroidectomy | |
| US20100233722A1 (en) | Methods for determining the biological effect and/or activity of r pharmaceutical compositions based on their effect on the methylation status of the DNA | |
| NO20032697D0 (en) | Test strip assay system and assay method for detection and / or determination of specific nucleic acid sequences | |
| CN116219020B (en) | Methylation reference gene and application thereof | |
| EP2808397A2 (en) | Method for obtaining information on colon cancer and marker and kit for obtaining information on colon cancer | |
| CA2462932A1 (en) | Method for the detection of cytosine methylations in immobilized dna samples | |
| CA2451483A1 (en) | Methods for detecting and monitoring cox-2 rna in plasma and serum | |
| WO1996021042A3 (en) | Primers for the pcr amplification of metastatic sequences | |
| US20080286784A1 (en) | Method for Detection of DNA Methyltransferase RNA in Plasma and Serum | |
| CN100371459C (en) | Kit with fluorescent quantitative RT-PCR detection technique used for cell keratin 19(Ck19)mRNA | |
| JP6269493B2 (en) | Method for acquiring information on brain tumor, and marker and kit for acquiring information on brain tumor | |
| CA2172142A1 (en) | Primers and probes for the amplification and detection of cmv nucleic acid | |
| RU2003125486A (en) | METHOD FOR EARLY DIAGNOSIS OF DISEASES ASSOCIATED WITH DISTURBANCE OF FUNCTIONING OF THE CELL GENETIC APPARATUS | |
| US20100159464A1 (en) | Method for Detection of DNA Methyltransferase RNA in Plasma and Serum | |
| Singhal et al. | Current status of cell-free DNA in head and neck cancer management | |
| CN115786503B (en) | DNA methylation marker combination and kit for early screening of gastric cancer |
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