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WO2002061092A3 - Regulation of human lysyl oxidase - Google Patents

Regulation of human lysyl oxidaseDownload PDF

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Publication number
WO2002061092A3
WO2002061092A3PCT/EP2002/000807EP0200807WWO02061092A3WO 2002061092 A3WO2002061092 A3WO 2002061092A3EP 0200807 WEP0200807 WEP 0200807WWO 02061092 A3WO02061092 A3WO 02061092A3
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WO
WIPO (PCT)
Prior art keywords
lysyl oxidase
human lysyl
regulation
reagents
diseases
Prior art date
Application number
PCT/EP2002/000807
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French (fr)
Other versions
WO2002061092A2 (en
Inventor
Yonghong Xiao
Original Assignee
Bayer Ag
Yonghong Xiao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Bayer Ag, Yonghong XiaofiledCriticalBayer Ag
Publication of WO2002061092A2publicationCriticalpatent/WO2002061092A2/en
Publication of WO2002061092A3publicationCriticalpatent/WO2002061092A3/en

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Abstract

Reagents that regulate human lysyl oxidase and reagents which bind to human lysyl oxidase gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, COPD, cancer cardiovascular disease, genitourinary diseases, and metabolic diseases.
PCT/EP2002/0008072001-01-292002-01-25Regulation of human lysyl oxidaseWO2002061092A2 (en)

Applications Claiming Priority (6)

Application NumberPriority DateFiling DateTitle
US26431301P2001-01-292001-01-29
US60/264,3132001-01-29
US30760901P2001-07-262001-07-26
US60/307,6092001-07-26
US33095401P2001-11-052001-11-05
US60/330,9542001-11-05

Publications (2)

Publication NumberPublication Date
WO2002061092A2 WO2002061092A2 (en)2002-08-08
WO2002061092A3true WO2002061092A3 (en)2003-08-28

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Family Applications (1)

Application NumberTitlePriority DateFiling Date
PCT/EP2002/000807WO2002061092A2 (en)2001-01-292002-01-25Regulation of human lysyl oxidase

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WO (1)WO2002061092A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US8163494B2 (en)2002-11-272012-04-24Technion Research & Development Foundation Ltd.Method for assessing metastatic properties of breast cancer
US8461303B2 (en)2007-08-022013-06-11Gilead Biologics, Inc.LOX and LOXL2 inhibitors and uses thereof
US8927700B2 (en)2009-08-212015-01-06Gilead Biologics, Inc.Catalytic domains from lysyl oxidase and LOXL2
US9107935B2 (en)2009-01-062015-08-18Gilead Biologics, Inc.Chemotherapeutic methods and compositions

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
FR2855968B1 (en)2003-06-132012-11-30Coletica STIMULATION OF THE SYNTHESIS AND ACTIVITY OF A LYSYL OXIDASE-LIKE LOXL ISOFORM TO STIMULATE THE FORMATION OF ELASTIC FIBERS
FR2855969B1 (en)*2003-06-132012-11-30Coletica STIMULATION OF THE ACTIVITY OF A LYSYL OXIDASE ISOFORM TO FIGHT CERTAIN PATHOLOGIES DUE TO AN INCOMPLETE, ABSENT OR DISORGANIZED ELASTOGENESIS
EP1706139A4 (en)2004-01-232009-06-17Massachusetts Eye & Ear InfirmLysyl oxidase-like 1 (loxl1) and elastogenesis
JP4954450B2 (en)*2004-06-142012-06-13ビーエーエスエフ ビューティ ケア ソリューションズ フランス エスエーエス Induction of lysyl oxidase isoform activity to address disease states due to failure, loss or disorder of elastic fiber formation
CA2951535A1 (en)*2014-06-112015-12-17Gilead Sciences, Inc.Methods for treating cardiovascular diseases
CN113321743B (en)*2021-07-022022-10-21海南精准医疗科技有限公司Chimeric antigen receptor of targeting lysyl oxidase 1 and application thereof

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EBI; 17 March 1997 (1997-03-17), SAITO H. ET AL.: "Human lysyl oxidase-related protein (WS9-14) mRNA, complete cds.", XP002227338, Database accession no. U89942*
DATABASE EMBL [online] EBI; 25 August 2000 (2000-08-25), STRAUSBERG R.: "601462492F1 NIH_MGC_67 Homo sapiens cDNA clone IMAGE:3865799 5', mRNA sequence.", XP002227337, Database accession no. BE618237*
DATABASE EMBL [online] EBI; 29 September 2000 (2000-09-29), SUGANO S. ET AL.: "Homo sapiens cDNA: FLJ21889 fis, clone HEP03178.", XP002227336, Database accession no. AK025542*
DATABASE EMBL [online] EBI; 7 January 2002 (2002-01-07), MEYERS R.: "Sequence 2 from patent WO0192495", XP002227339, Database accession no. AX323480*
DATABASE SWISSPROT [online] 1 May 1999 (1999-05-01), LANGENAU D.M. ET AL: "Lysyl oxidase-like protein (Fragment).", XP002227334, Database accession no. Q9YHC1*
DATABASE SWISSPROT [online] 1 November 1999 (1999-11-01), LANGENAU D.M. ET AL: "Lysyl oxidase related protein homolog.", XP002227335, Database accession no. Q9W6N1*

Cited By (7)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US8163494B2 (en)2002-11-272012-04-24Technion Research & Development Foundation Ltd.Method for assessing metastatic properties of breast cancer
US8461303B2 (en)2007-08-022013-06-11Gilead Biologics, Inc.LOX and LOXL2 inhibitors and uses thereof
US8679485B2 (en)2007-08-022014-03-25Gilead Biologics, Inc.Methods and compositions for treatment and diagnosis of fibrosis, tumor invasion, angiogenesis, and metastasis
US9176139B2 (en)2007-08-022015-11-03Gilead Biologics, Inc.LOX and LOXL2 inhibitors and uses thereof
US9107935B2 (en)2009-01-062015-08-18Gilead Biologics, Inc.Chemotherapeutic methods and compositions
US9289447B2 (en)2009-01-062016-03-22Gilead Biologics, Inc.Chemotherapeutic methods and compositions
US8927700B2 (en)2009-08-212015-01-06Gilead Biologics, Inc.Catalytic domains from lysyl oxidase and LOXL2

Also Published As

Publication numberPublication date
WO2002061092A2 (en)2002-08-08

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