USRE33569E - Single lumen atherectomy catheter device - Google Patents

Abstract

Atherectomy device for removing material from an atheroma in the vascular system. A cutter is mounted in a cylindrical housing having a cutout on one side thereof at the distal end of a catheter. The catheter has a single luminal opening, and a flexible drive cable for operating the cutter passes through this opening. An inflatable balloon is positioned outside the housing opposite the cutout, and a medium for inflating the balloon is introduced through luminal opening of the catheter.

Description

.Iadd.This is a reissue of application Ser. No. 834,950 filed Feb. 28, 1986, now U.S. Pat. No. 4,669,469. .Iaddend.

This invention relates to atherectomy catheter devices and particularly to a single lumen atherectomy catheter device.

In co-pending application Ser. No. 732,691 filed on May 10, 1985, there is disclosed an atherectomy device which utilizes a multi-lumen flexible tubing. One of the lumens can be utilized for the cutter cable whereas another lumen can be utilized as a balloon inflating lumen. Other lumens may be used for introducing radiopaque materials or making pressure measurements and the like. It has been found that the use of such a multi-lumen tubing has certain disadvantages, particularly when it is desired to make a very small catheter apparatus which can be utilized in conjunction with the heart, kidney and the like. By way of example, it is desirable to have tubing which will make possible a five French device and possibly as small a device as a three French device. In addition to having a smaller size, there is the additional desirability of having a tubing which is very flexible. There is therefore a need for a new and improved single lumen atherectomy catheter or a device.

In general, is an object of the present invention to provide an atherectomy catheter which utilizes a single lumen.

Another object of the invention is to provide a device of the above character which can be made very small.

Another object of the invention is to provide a device of the above character which is very flexible.

Another object of the invention is to provide a device of the above character which utilizes a movable guide wire.

Additional objects and features of the invention will appear from the following description in which the preferred embodiments are set forth in detail in conjunction with the accompanying drawings.

FIG. 1A is a view partially in cross section of the proximal end portion of a single lumen catheter incorporating the present invention.

FIG. 1B is an enlarged cross sectional view of the distal end portion of a single lumen catheter incorporating the present invention.

In general the atherectomy device of the present invention is used for removal of material from a atheroma in a vessel of the vascular system of a patient. It is comprised of a generally cylindrical housing having a cutout therein extending longitudinally of the housing on one side of the housing. Atheroma cutting means is disposed within the housing. Flexible guiding means is secured to the proximal end of the housing for advancing the housing into the vessel. Flexible drive means is connected to the atheroma cutting means for operating the atheroma cutting means. Balloon-like inflatable means is carried by the housing and is disposed on the exterior of the housing in a region opposite the side in which the cutout is formed. The flexible guiding means having only a single lumen extending therethrough with the flexible drive means extending through the lumen. Means is coupled to the balloon for establishing communication between the balloon and the single lumen. Fluid-tight means is carried by the housing and the flexible drive means for establishing fluid-tight sealing means between the flexible drive means and the single lumen so that fluid-tight seals are provided between the distal and proximal extremities of the single lumen and the flexible drive means. Means is coupled to the flexible guiding means and in communication with the single lumen in the guiding means for introducing an inflatable medium into the single lumen for inflating the balloon-like member.

More in particular as shown in the drawing, the atherectomy device 11 of the present invention consists of an elongate flexibletubular member 12 formed of suitable plastic material and which can be provided if desired with a braidedreinforcement 13. The flexibletubular member 12 can have an outside diameter ranging from 0.050 to 0.200 inches. It is provided with a single orsole lumen 16 extending the length thereof from the proximal to the distal extremities. Afitting 17 is provided near the proximal extremity of the flexibletubular member 12. Thefitting 17 serves as a catheter tube attachment. Another fitting 18 is threadedly mounted therein. A rotatingseal assembly 19 is mounted in the fitting 18. Asingle arm adapter 21 is mounted in the rotatingseal member 19. As shown in FIG. 1, the proximal extremity of the flexibletubular member 12 extends through thefitting 17 and 18 and through the rotatingseal device 19. Thereafter it passes into the proximal extremity of thefitting 21. Theside arm 22 of thefitting 21 is in communication with the single or sole passage orlumen 16 in the flexibletubular member 12 and serves as a balloon inflation port.

Another fitting 23 is mounted in theadapter 21. Theadapter 21 is provided with aflow passage 24 and the fitting 23 is provided with aflow passage 26. A flexible hollowcutter drive cable 27 is disposed in thepassages 24 and 26 in thefittings 21 and 23 and extends into thesingle lumen 16 provided in the flexibletubular member 12. A fitting 28 having a knurled flange orknob 29 is threaded into the fitting 23 and engages an O-ring 32. Thedrive cable 27 extends through apassage 33 provided in thefitting 28. The O-ring 32 forms a fluid-tight seal between the fitting 23 and theflexible drive cable 27. Thefitting 28 is provided with a tapered portion 28c which is adapted to form a friction fit with atapered bore 34 in amotor drive unit 35 of the type described in co-pending application Ser. No. 843,743 filed Feb. 28, 1986.

Ahousing 36 is mounted on the distal extremity of the flexibletubular member 12 and can be formed on a suitable material such as stainless steel. It is generally cylindrical as shown and has its proximal extremity secured to the distal extremity of the flexibletubular member 12 as shown particularly in FIG. 1B. Acutout 37 is provided in thehousing 36 in one side thereof and faces in a direction which is generally perpendicular to the longitudinal axis of the housing. A work performing device in the form of acutter 38 is slidably mounted in thehousing 36 and is provided with acircular cutting edge 39 which lies in a plane perpendicular to the longitudinal axis of the housing and the axis of longitudinal movement for thecutter 38. A bell-shaped recess 41 is provided within thecutter 38 and extends rearwardly from thecutting edge 39. Thecutter 38 is provided with ahub 42 which is secured to the distal extremity of theflexible drive cable 27.

Means is provided for forming a fluid-tight seal between the housing and theflexible drive cable 27 and consists of asleeve 43 which is secured within the housing by suitable means such as an adhesive and which is provided with a passage 44 through which theflexible drive cable 27 extends. An O-ring 46 is mounted in arecess 47 and is held in place by aretaining ring 48. With the construction shown, the O-ring 46 is compressed in such a manner so as form a fluid-tight seal between thesleeve 43 and theflexible drive cable 27.

Means is provided on the exterior of thehousing 36 for yieldably urging the housing in the direction thecutout 37 faces and consists of aninflatable balloon 51 which is secured to the housing by suitable means such as an adhesive. The distal extremity of the balloon can be secured in a suitable manner to anose piece 52 by suitable means such asnylon wire 53 wound into arecess 54 provided in thenose piece 52. Thenose piece 52 is secured in the open distal end of thehousing 36 by suitable means such as an adhesive. Thenose piece 52 is provided with a roundedforwardly extending surface 55.

A conventional flexibleelongate guide wire 56 provided with ahelical coil spring 57 at its distal extremity is removably mounted in the atherectomy device. Theguide wire 56 extends through the hollowflexible drive cable 27, through abore 58 in thecutter 38, thehousing 36 and through abore 59 provided in thenose piece 52. Theguide wire 56 serves as a guiding element for inserting the catheter into a vessel in the vascular system of a patient.

As shown in FIG. 1B, thenose piece 52 is provided with a relativelylarge recess 61 which opens up into the interior of thehousing 36 and extends forwardly from the housing.

The proximal extremity of theballoon 51 is connected in a suitable manner with the single orsole lumen 16 in theflexible tubular member 12 so that the balloon can be inflated and deflated as desired. Thus as shown, the balloon is provided with a reinforcedproximal extremity 66 which extends through ahole 67 provided in thehousing 27 and opens into aspace 68 forward of thesleeve 43 and distal of the distal extremity of theflexible tubular member 12 so that thespace 68 is in communication with thesingle lumen 16.

As described in copending application Ser. No. 843,743, filed Feb. 28, 1986, athumb flipper member 71 is provided which is secured to theflexible drive cable 27 for moving theflexible drive cable 27 and thecutter 28 carried thereby longitudinally of the axis of rotation of thedrive cable 27.

The operation and use of the single lumen atherectomy catheter or device may now be briefly described as follows. In general, the mode of operation of this atherectomy device is very similar to that described in co-pending application Ser. No. 732,691 filed on May 10, 1986. As described in that co-pending application, the atherectomy device 11 can be utilized for removing atheromas or at least portions thereof from a vessel in the vascular system of a patent such as an arterial vessel of the heart. Themovable guide wire 56 is inserted into the atherectomy device 11 after theguide wire 56 has been inserted into the vessel of the patient with its distal extremity in the desired position. The proximal extremity of theguide wire 56 is threaded into thenose piece 52, thecutter 38 and into thehollow cutter cable 27. After the device has been inserted into the arterial vessel and is positioned in such a manner so that thecutout 37 is opposite the atheroma, theballoon 51 can be inflated by introducing an inflating medium through thesingle lumen 16 to urge thehousing 36 toward the atheroma so that the atheroma enters thecutout 37. If desired, theguide wire 56 now can be removed and themotor drive unit 35 attached.

With thecutout 37 held in place by theinflated balloon 51, thecutter 38 can be rotated by themotor drive unit 35 to cause rotation of theflexible drive cable 27 and thecutter 38 mounted thereon. Thecutter 38 can be advanced by operating theflipper member 71 in a manner described in copending application Ser. No. 843,743 filed Feb. 28, 1986 to advance the cutter to engage the atheroma which has been forced into thecutout 37. The material which is shaved off or removed by the cutter is collected in therecess 41 within the cutter and also can be collected by therecess 61 in thehousing 36 as the cutter is advanced beyond the cutout. Thereafter, the ahterectomy device can be removed and the material which has been collected within therecesses 41 and 61 are removed. If necessary, the atherectomy device 11 can be inserted repeatedly into the arterial passagee and additional cuts made until as much as desired, or at least a substantial portion of the atheroma has been removed from the vessel so as to permit increased blood flow through the vessel.

From the foregoing it can be seen that the present atherectomy device can be utilized for the same shaving operations on the vessel wall as the atherectomy device disclosed in co-pending application Ser. No. 732,651 filed on May 10, 1985. The construction of the present atherectomy device, however, is much similar because of its use of asingle lumen 16 in the flexible tubular member. As can be seen from the construction hereinbefore described, theflexible drive cable 27 for thecutter 38 is disposed in thissingle lumen 16 which is made possibly by the use of seals provided at the distal and proximal extremities of the flexible drive cable in the form of the O-rings 31 and 46. This construction also makes it possible to utilize the samesingle lumen 16 for the balloon inflation lumen which can be inflated from theballoon inflation port 22. Theballoon 51 is attached to thehousing 36 in such a manner so that its proximal extremity opens up directly into thesingle lumen 16.

In addition with the construction shown, the use of therotation member 19 and the rotatable seal provided by the O-ring 46 makes it possible to rotate thehousing 27 and thetubular member 12 independent of themotor drive unit 35 and any balloon inflation device connected to theport 22. This facilitates use of the atherectomy device on the operating table when performing the desired operations on the patient.

Also one of the more important features of the present construction for an atherectomy device is that it lends itself to smaller atherectomy devices. Thus an atherectomy device as small as a five French device or even a three French device can be made. The five French device has an outer diameter of less than 0.065, whereas a three French device has an outer diameter of 0.039. By providing atherectomy devices of such a size, it is possible to perform operations in very small blood vessels, as for example, those associated with the heart and kidney, as well as other organs in the body. The construction of the atherectomy device also permits use of a movable guide wire, if desired, in place of a fixed guide wire.

From the foregoing it is apparent that there has been provided an improved atherectomy catheter device which utilizes a single lumen which is particularly useful in connection with making smaller atherectomy devices.

Claims (11)

What is claimed is:

1. In an atherectomy device for removal of material from an atheroma in a vessel of the vascular system of a patient, a generally cylindrical housing, said housing being formed with a cutout extending longitudinally of the housing on one side of the housing, atheroma cutting means disposed within the housing, flexible guiding means secured to the proximal end of the housing for advancing the housing into the vessel, flexible drive means connected to the atheroma cutting means for operating the atheroma cutting means, balloon-like inflatable means carried by the housing and disposed on the exterior of the housing opposite the side in which the cutout is formed, said flexible guiding means having only a single lumen extending therethrough, said flexible drive means extending through said single lumen, means coupled to the balloon for establishing communication between the balloon and the single lumen, means including a balloon inflation port coupled to the flexible guiding means and in communication with the single lumen in the guiding means for introducing an inflatable medium into the single lumen for inflating the balloon-like member and fluid-tight means carried by the housing and the flexible guiding means for establishing proximal and distal seals about the flexible drive means so that the single lumen provides a fluid-tight passage between the balloon inflation port and the balloon.

2. A device as in claim 1 together with rotatable coupling means connecting the flexible guiding means to the means forming an inflation port connected into the single lumen so as to permit rotation of the housing and the flexible guiding means independent of rotation of the means providing an inflation port and the flexible drive means.

3. A device as in claim 1 wherein the proximal seal is disposed proximal of the means forming an inflation port.

4. A device as in claim 1 wherein said distal sealing means is disposed distal of the distal extremity of the single lumen.

5. A device as in claim 1 wherein said distal sealing means is disposed within the housing.

6. A device as in claim 1 together with a movable guide wire carried by the same.

7. A device as in claim 6 wherein the movable guide wire extends through the flexible drive means. .Iadd.

8. A device comprising:

flexible guiding means having a lumen extending from a proximal end to a distal end thereof;

a housing mounted on the distal end of the flexible guiding means, said housing having a cutout therein;

flexible drive means extending through the lumen of the flexible guiding means and into the housing;

a work performing device secured to the flexible drive means;

inflatable means carried by the housing;

means coupling the inflatable means to the lumen; and

means for establishing fluid-tight sealing between the lumen and the interior of the housing, said means allowing the passage of the drive means therethrough. .Iaddend. .Iadd.

9. A device as in claim 8, wherein the inflatable means is an inflatable balloon. .Iaddend. .Iadd.10. A device as in claim 8, wherein the means for

establishing fluid-tight sealing is an O-ring. .Iaddend. .Iadd.11. A device comprising:

an elongate flexible tubular member having a lumen extending from a proximal end to a distal end thereof;

a housing having a cutout therein mounted on the distal end of the flexible tubular member proximate an opening of the lumen;

a flexible drive cable extending through the lumen of the flexible tubular member and into the housing;

a work performing device secured to the distal end of the flexible drive cable within the housing;

an inflatable balloon secured to the exterior of the housing;

means for connecting the balloon to the lumen in the flexible tubular member whereby the balloon can be inflated and deflated; and

means for forming a fluid-tight seal between the flexible tubular member and the interior of the housing, whereby the flexible drive cable can pass from the lumen of the tubular member to the housing while maintaining said

fluid-tight seal. .Iaddend. .Iadd.12. A device as in claim 11, wherein the flexible drive cable is hollow and an axial bore is provided in the housing, whereby the atherectomy device can receive a movable guide wire. .Iaddend. .Iadd.13. A device as in claim 11, wherein the housing has a cutout provided in a side thereof opposite to the balloon. .Iaddend. .Iadd.14. A device as in claim 13, wherein the work performing device is a cutter, whereby the cutter may be moved longitudinally past the cutout by the flexible drive cable. .Iaddend. .Iadd.15. A device as in claim 11, wherein the means for connecting the balloon to the lumen includes a reinforced extremity of the balloon passing through a hole in the housing, said hole being located proximally relative to the fluid-tight sealing means. .Iaddend. .Iadd.16. A device as in claim 11, wherein the means for forming a fluid-tight seal is an O-ring. .Iaddend.

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