USRE26006E - Transfusion set - Google Patents
Transfusion setDownload PDFInfo
- Publication number
- USRE26006E USRE26006EUS26006DEUSRE26006EUS RE26006 EUSRE26006 EUS RE26006EUS 26006D EUS26006D EUS 26006DEUS RE26006 EUSRE26006 EUS RE26006E
- Authority
- US
- United States
- Prior art keywords
- chamber
- blood
- tube
- pressure
- bag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008280bloodSubstances0.000description178
- 210000004369bloodAnatomy0.000description178
- 230000001105regulatory effectEffects0.000description27
- 239000000543intermediateSubstances0.000description26
- 229920002457flexible plasticPolymers0.000description20
- 238000004891communicationMethods0.000description16
- 239000012530fluidSubstances0.000description15
- 229920003023plasticPolymers0.000description12
- 230000009975flexible effectEffects0.000description8
- 230000005484gravityEffects0.000description5
- 238000007789sealingMethods0.000description5
- 230000017531blood circulationEffects0.000description4
- 238000003780insertionMethods0.000description4
- 230000037431insertionEffects0.000description4
- 239000007788liquidSubstances0.000description4
- 230000006835compressionEffects0.000description2
- 238000007906compressionMethods0.000description2
- 206010001526Air embolismDiseases0.000description1
- 208000036366Sensation of pressureDiseases0.000description1
- 238000007792additionMethods0.000description1
- 230000000903blocking effectEffects0.000description1
- 238000001914filtrationMethods0.000description1
- 238000000034methodMethods0.000description1
- 210000002445nippleAnatomy0.000description1
- 230000002093peripheral effectEffects0.000description1
- 238000004321preservationMethods0.000description1
- 230000000630rising effectEffects0.000description1
- 239000007787solidSubstances0.000description1
- 238000001356surgical procedureMethods0.000description1
- 210000003462veinAnatomy0.000description1
Images
Classifications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/12—Pressure infusion
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/24—Medical-surgical bags
Definitions
- This inventionis an expendable transfusion set for gravity or pressure use in which the flow is easily observed in a transparent drip chamber and can be regulated from a slow drip to full flow with the drip level remaining constant at all rates of flow, even under the highest pressures.
- FIG. 1shows the transfusion set ready for use
- FIG. 2is a front view of the combined blood and pressure chamber envelope in pre-use condition
- FIG. 3is a section on line 3-3 of FIG. 2 with the normally flat walls of the blood and pressure chambers spread apart for the purpose of illustration
- FIG. 4is a view of the drip chamber under slow drip conditions
- FIG. 5is a similar view of the drip chamber under full flow conditions.
- 1indicates a blood bottle or similar container for liquid to be administered supported by a bail 2 on a hook 3 on a suitable stand.
- a rubber stopper 4At the lower end of the bottle is a rubber stopper 4 through which is inserted the cannula 5 of a transfusion set to connect the set to the bottle. 5a is in air inlet tube.
- the flow of blood from the cannulais through a flexible plastic tube 6 controlled by a clamp 7.
- the lower end of the tube 6is sealed to the upper end of a plastic walled blood chamber 8 and discharges to the interior of a suitable tubular filter 9 so that all of the blood flowing into the blood chamber must pass through the filter.
- a suitable tubular filter 9so that all of the blood flowing into the blood chamber must pass through the filter.
- FIG. 2there is a short length 10 of flexible plastic tubing heat sealed to the lower end of the tube 6 and leading to the upper end of the filter 9.
- the tubing 6 and 10is transparent and when the blood chamber 8 is filled, the blood rises into the tubing 11) and blood chamber 8 may be squeezed to force air above the clamp 7, after which the tubing 6 is shut off by the clamp 7 so that there is no air within the blood chamber to cause air embolism.
- the blood chamber 8is made from two sheets 11, 12 0t flexible plastic, heat sealed around the periphery as indicated at 13 and likewise heat sealed to the tube 10 at 15 and to the lower tube 19 at 20.
- the filteris sealed into the tube 10 at 14.
- On the opposite side of the sheet 12is another sheet 16 of flexible plastic which is heat sealed around the periphery at the same time the sheets 11 and 12 are heat sealed to form the blood chamber.
- the space between the sheets 12 and 16provides a pressure chamber into which air may be pumped by a squeeze bulb pump 17 attached to a nipple 18 in the sheet 16. The air pressure is applied to the blood through the flexible sheet 12 thereby developing hydraulic pressure in the blood without running the risk of air entering blood chamber 8.
- a draw-off tube 19having its upper end 20 projecting slightly above the bottom wall of the blood chamber, e.g. /1 inch.
- the projection 20permits substantially complete drainage of the blood chamber. Without the projection 20, as much as from to cc. of blood may be trapped between the flexible walls 11 and 12 of the blood chamber no matter how much pressure is applied.
- the draw-oil tubeis scaled to a metering device such as a plastic drip chamber 21 with its lower end 22 projccting into the chamber in the usual manner so that the blood can fall into the drip chamber in the form of drops which can be counted.
- a drip levelis established at 23 providing a pool of blood which drains through dispensing tubing 24 to the needle 25.
- the flow of bloodis controlled by a regulating clamp 26 of any suitable kind, for example of the type shown in co-pending application Serial No. 789,662 filed January 28, 1959, now abandoned. When the regulating clamp 26 shuts oil flow in the tube 24, no blood flows into the drip chamber.
- the bloodflows at progressively increased rates. At slow flows, the blood flows in the form of drops as indicated at 27 in FIG. 4. At maximum How, the blood flows in a solid stream as indicated at 28 in FIG. 5. Under all conditions, the drip level 23 remains substantially constant although under pressure, there may be a temporary slight rising of the liquid level due to compression of the air trapped in the drip chamber above the liquid level.
- the transfusion setmay be used for gravity feed, in which case no pressure is applied to the compression chamber.
- the drip levelwill still be as indicated at 23.
- the rates of flow usual with gravity feedare also obtainable with pressure feed with the added advantage that when pressure is applied, it is also possible to obtain quickly the higher rates of flow which are only possible with pressure.
- the transfussion setis sufliciently low in cost to permit use as the standard administration set for all surgical transfusions. While pressure may not be needed, it is always instantly available should an emergency arise.
- the setcan be used for other liquids either separately or together with blood.
- the pressure chamberis exhausted and the cannula S is removed from the stopper 4 of the preceding bottle and inserted in the stopper of a new bottle to refill the blood chamber after which the transfusion proceeds by gravity or pressure as desired.
- the filter 9has capacity sufficient for the maximum number of units of blood to be given any patient at one time.
- the setpermits the filtration of blood to take place prior to administration without the use of additional equipment.
- blocking of the filtercannot occur during administration when the patient may require blood without delay.
- iteliminates the present practise of exerting gas pressure in the bottle itself where the air may enter the vein through the transfusion set of the clamp is not closed immediately after the bottle empties of blood, possibly causing death of the patient.
- An expandable unitary transfusion set assemblycomprising a bag having flexible plastic outer walls and an intermediate flexible plastic wall peripherally sealed to the outer walls and dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shubotf, a filter within the blood chamber in the path of flow of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber, a drip chamber permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing.
- said drip chamberhaving a drip level above its lower end, a flow regulating clamp in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp.
- An expendable unitary transfusion set assemblycomprising a bag having flexible plastic outer walls and an intermediate flexible plastic wall peripherally sealed to the outer walls and dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shut-Oil, a filter within the blood chamber in the path of how of blood from the blood bottle to the blood chamber.
- a drain tubepermanently sealed to and leading from the lower end or" the blood chamber
- a drip chamberpermanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow regulating clamp in the dispensing tubing, a squeeze bulb pressure pump, a fitting in the pressure chamber for connection to said squeeze bulb for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said how regulating clamp.
- An expendable unitary transfusion set assemblycomprising a bag having flexible plastic outer walls and an intermediate flexible plastic wall dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shut-oil, a filter within the blood chamber in the path of How of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber, the upper end of the drain tube projecting slightly above the lower end of the blood chamber, a drip chamber permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow regulating clamp in the dispensing tubing, and a means for supplying 'liuid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp.
- An expendable unitary transfusion set assemblycomprising a bag having collapsible plastic outer walls and an intermediate plastic wall sandwiched between and sealed to the outer walls and dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a tube permanently sealed to and connected between the upper end of the blood chamber and a cannula for insertion in the stopper of a blood bottle, said tube including a shut-oil, a filter Within the blood chamber sealed to said tube and in the path of flow of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber, a drip chamber permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow adjusting clamp in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate limited
- An expendable unitary transfusion set assemblycomprising a plastic bag having two collapsible chambers respectively on one and on the opposite side of a common flexible plastic wall shared by the chambers and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shutoll, an inlet tube and a shut-off in the tube through which the air in the blood chamber can be expelled by squeezing the chamber prior to closing the drain tube permanently sealed to and leading from the lower end of the blood chamber to dispensing tubing, flow indicating and regulating means in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating means.
- An expendable unitary transfusion set assemblycomprising a plastic bag having two collapsible chambers respectively on one and on the oppsite side of a common flexible plastic wall shared by the chambers and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamher to a blood bottle and including an inlet tube and a shut-off in the tube through which the air in the blood chamber can be expelled by squeezing the chamber prior to closing the shut-off, a drain tube permanently sealed to and leading from the lower end of the blood chamber, a drip chamber permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a filter in the path of flow of blood to the drip chamber, a flow regulating means in the dispensing tubing. and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating means.
- An expendable unitary transfusion set assemblycomprising a bag having flexible plastic outer walls and an intermediate flexible plastic wall dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shut-oil, a filter within the blood chamber in the path of flow of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber, a metering device permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, a flow regulating clamp in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp.
- An expendable unitary transfusion set assemblycomprising a bag having flexible plastic outer walls and an intermediate flexible plastic wall dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shut-off, a filter within the blood chamber in the path of flow of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber to dispensing tubing, a flow regulating device in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate con trollable by said flow regulating device.
- An expendable unitary transfusion set assemblycomprising a bag having collapsible plastic outer walls and an intermediate plastic Wall sandwiched between and sealed to the outer walls and dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pres sure chamber, a tube permanently sealed to and connected between the upper end of the blood chamber and a cannula for insertion in the stopper of a blood bottle, said tube including a shut-off, a filter within the blood chamber in the path of flow of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber to dispensing tubing, a flow adjusting means in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate limited by said flow adjusting means.
- An expendable unitary transfusion set assemblycomprising a plastic bag having two collapsible chambers respectively on one and on the opposite side of a common flexible plastic wall shared by the chambers and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including an inlet tube and a shutoff in the tube through which the air in the blood chamber can be expelled by squeezing the chamber prior to closing the shut-oil, a drain tube permanently sealed to and leading from the lower end of the blood chamber, a flow indicator permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, a filter in the path of flow of blood to the flow indicator, a flow regulating means in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating means.
- a unitary transfusion set assemblycomprising a bag having collapsible outer walls and an intermediate wall sandwiched between and sealed to the outer walls and dividing the bag into two chambers respectively on one and on the opposite side of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a cannula for insertion in the stopper of a blood bottle, a tube having its upper end connected to said cannula, a shut off clamp on said tube, a tubular filter having a closed lower end within the blood chamber and having an open upper end, means sealing the open upper end of the filter to the lower end of said tube whereby blood flowing from the tube into the blood chamber flows through said filter, a drain tube leading from the lower end of the blood chamber, a drip chamber connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow adjusting clamp in the dispensing tubing, and a means for supplying fluid under pressure to said pressure
- a unitary transfusion set assemblycomprising a bag having collapsible outer walls and an intermediate wall sandwiched between and sealed to the outer walls and dividing the bag into two chambers respectively on one and on the opposite side of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a cannula for insertion in the stopper of a blood bottle, a tube having its upper end connected to said cannula, a shut off clamp on said tube, a tubular filter having a closed lower end within the blood chamber and having an open upper end, means sealing the open upper end of the filter to the lower end of said tube whereby blood flowing from the tube into the blood chamber flows through said filter, a drain tube leading from the lower end of the blood chamber to dispensing tubing, a flow adjusting means in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate limited by said flow adjusting means.
- a unitary transfusion set assemblycomprising a bag having flexible outer walls and an intermediate flexible wall peripherally sealed to the outer walls and dividing the bag into two chambers respectively on one and on the opposite side of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a tube having at its upper end means for connecting to a hood bottle, a shut off clamp on said tube, a tubular filter having a closed lower end within the blood chamber and having an open upper end, means sealing the open upper end of the filter to the lower end of said tube whereby blood flowing from the tube into the blood chamber flows through said filter, a drain tube leading from the lower end of the blood chamber, a drip chamber connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow regulating clamp in the dispensing tubing, a squeeze bulb pressure pump, a fitting in the pressure chamber for connection to said squeeze bulb and supplying fluid under pressure to said pressure chamber to force the blood out
- a unitary transfusion set assemblycomprising a bag having flexible outer walls and an intermediate flexi ble wall dividing the bag into two chambers respectively on one and on the opposite side of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a tube having at its upper end means for connecting to a blood bottle, a shut oil.
- a tubular filterhaving a closed lower end within the blood chamber and having an open upper end, means sealing the open upper end of the filter to the lower end of said tube whereby blood flowing from the tube into the blood chamber flows through said filter, a drain tube leading from the lower end of the blood chamber, the upper end of the drain tube projecting slightly above the lower end of the blood chamber, a drip chamber connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow regulating clamp in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp,
- a unitary transfusion set assemblycomprising a bag having flexible outer walls and an intermediate flexible wall dividing the bag into two chambers respectively on one and on the opposite side of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a tube having at its upper end means for connecting to a blood bottle, a shut off clamp on said tube, a tubular filter having a closed lower end within the blood chamber and having an open upper end, means sealing the open upper end of the filter to the lower end of said tube whereby blood flowing from the tube into the blood chamber flows through said filter, a drain tube leading from the lower end of the blood chamber, a metering device connected at its upper end to said drain tube and at its lower end to dispensing tubing, a flow regulating claim pin the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp.
- a unitary transfusion set assemblycomprising a bag having two collapsible chambers respectively on one and on the opposite side of a common flexible plastic wall shared by the chambers and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a tube having at its upper end means for connecting to a blood bottle, a shut oil clamp on said tube, said tube having its lower end sealed to said blood chamber, a drain tube leading from the lower end of the blood chamber to dispensing tubing, flow indicating and regulating means in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said fiow regulating means.
- a blood baghaving spaced flexible plastic walls, a plastic inlet tube having one end entering and sealed to the bag, [a shut-oil in the tube] said tube having associated shut-0] ⁇ means through which air may be expelled by squeezing the bag prior to closing the shut-oft, an outlet from the bag for conducting blood to a patient, another Wall outside and sealed at its edges to one of the Walls of the bag and forming therewith a pressure chamber external to the bag, and a pressure pump connected to said other Wall for developing a pressure on said one wall of the bag forcing blood under pressure out through said outlet.
- the administration set of claim 17having in addition a filter within the blood bag sealed to the entering end of the inlet tube.
- the bag and pressure chambercomprise three sheets of flexible plastic arranged one on top of the other and sealed to each other around the peripheral edges, one of the outer sheets and the intermediate sheet comprising the blood bag, and the other of the outer sheets and the intermedi ate sheet comprising the pressure chamber.
- outletcomprises a plastic tube with one end entering and sealed to the bottom of the blood bag and projecting slightly above the bottom of the blood bag.
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
April 26, 1966 T. H. GEWECKE TRANSFUSION SET Original Filed Dec. 23, 1959 IN VEN TOR.
United States Patent 26,006 TRANSFUSICDN SET Theodore H. Geweclre, Baldwin, Ga., assignor, by mesne assignments, to McGaw Laboratories, Inc., Milledgeville, 6a., a corporation of Delaware Original No. 3,054,401, dated Sept. 18, 1962, Ser. No. 861,658, Dec. 23, 1959. Application for reissue Sept. 15, 1964, Ser. No. 410,838
20 Claims. (Cl. 128214) Matter enclosed in heavy brackets appears in the original patent but forms no part of this reissue specification; matter printed in italics indicates the additions made by reissue.
This invention is an expendable transfusion set for gravity or pressure use in which the flow is easily observed in a transparent drip chamber and can be regulated from a slow drip to full flow with the drip level remaining constant at all rates of flow, even under the highest pressures.
In the drawing, FIG. 1 shows the transfusion set ready for use, FIG. 2 is a front view of the combined blood and pressure chamber envelope in pre-use condition, FIG. 3 is a section on line 3-3 of FIG. 2 with the normally flat walls of the blood and pressure chambers spread apart for the purpose of illustration, FIG. 4 is a view of the drip chamber under slow drip conditions, and FIG. 5 is a similar view of the drip chamber under full flow conditions.
in the drawing, 1 indicates a blood bottle or similar container for liquid to be administered supported by abail 2 on ahook 3 on a suitable stand. At the lower end of the bottle is arubber stopper 4 through which is inserted thecannula 5 of a transfusion set to connect the set to the bottle. 5a is in air inlet tube. The flow of blood from the cannula is through a flexible plastic tube 6 controlled by aclamp 7.
The lower end of the tube 6 is sealed to the upper end of a plastic walledblood chamber 8 and discharges to the interior of a suitabletubular filter 9 so that all of the blood flowing into the blood chamber must pass through the filter. As shown more clearly in FIG. 2, there is ashort length 10 of flexible plastic tubing heat sealed to the lower end of the tube 6 and leading to the upper end of thefilter 9. Thetubing 6 and 10 is transparent and when theblood chamber 8 is filled, the blood rises into the tubing 11) andblood chamber 8 may be squeezed to force air above theclamp 7, after which the tubing 6 is shut off by theclamp 7 so that there is no air within the blood chamber to cause air embolism.
Theblood chamber 8 is made from twosheets 11, 12 0t flexible plastic, heat sealed around the periphery as indicated at 13 and likewise heat sealed to thetube 10 at 15 and to thelower tube 19 at 20. The filter is sealed into thetube 10 at 14. On the opposite side of thesheet 12 is anothersheet 16 of flexible plastic which is heat sealed around the periphery at the same time thesheets 11 and 12 are heat sealed to form the blood chamber. The space between thesheets squeeze bulb pump 17 attached to anipple 18 in thesheet 16. The air pressure is applied to the blood through theflexible sheet 12 thereby developing hydraulic pressure in the blood without running the risk of air enteringblood chamber 8.
At the lower end ofblood chamber 8 is a draw-offtube 19 having itsupper end 20 projecting slightly above the bottom wall of the blood chamber, e.g. /1 inch. Theprojection 20 permits substantially complete drainage of the blood chamber. Without theprojection 20, as much as from to cc. of blood may be trapped between theflexible walls 11 and 12 of the blood chamber no matter how much pressure is applied.
Reissued Apr. 25, 1966 The draw-oil tube is scaled to a metering device such as aplastic drip chamber 21 with itslower end 22 projccting into the chamber in the usual manner so that the blood can fall into the drip chamber in the form of drops which can be counted. in the lower end of the drip chamber, a drip level is established at 23 providing a pool of blood which drains through dispensingtubing 24 to theneedle 25. The flow of blood is controlled by a regulatingclamp 26 of any suitable kind, for example of the type shown in co-pending application Serial No. 789,662 filed January 28, 1959, now abandoned. When the regulatingclamp 26 shuts oil flow in thetube 24, no blood flows into the drip chamber. As the adjustment clamp is turned to open thetube 24, the blood flows at progressively increased rates. At slow flows, the blood flows in the form of drops as indicated at 27 in FIG. 4. At maximum How, the blood flows in a solid stream as indicated at 28 in FIG. 5. Under all conditions, thedrip level 23 remains substantially constant although under pressure, there may be a temporary slight rising of the liquid level due to compression of the air trapped in the drip chamber above the liquid level.
The transfusion set may be used for gravity feed, in which case no pressure is applied to the compression chamber. The drip level will still be as indicated at 23. However, the rates of flow usual with gravity feed are also obtainable with pressure feed with the added advantage that when pressure is applied, it is also possible to obtain quickly the higher rates of flow which are only possible with pressure.
The transfussion set is sufliciently low in cost to permit use as the standard administration set for all surgical transfusions. While pressure may not be needed, it is always instantly available should an emergency arise.
The set can be used for other liquids either separately or together with blood. When more than one unit is to be used, the pressure chamber is exhausted and the cannula S is removed from thestopper 4 of the preceding bottle and inserted in the stopper of a new bottle to refill the blood chamber after which the transfusion proceeds by gravity or pressure as desired. Thefilter 9 has capacity sufficient for the maximum number of units of blood to be given any patient at one time.
The set permits the filtration of blood to take place prior to administration without the use of additional equipment. Thus, blocking of the filter cannot occur during administration when the patient may require blood without delay. Furthermore, it eliminates the present practise of exerting gas pressure in the bottle itself where the air may enter the vein through the transfusion set of the clamp is not closed immediately after the bottle empties of blood, possibly causing death of the patient.
What is claimed as new is:
1. An expandable unitary transfusion set assembly comprising a bag having flexible plastic outer walls and an intermediate flexible plastic wall peripherally sealed to the outer walls and dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shubotf, a filter within the blood chamber in the path of flow of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber, a drip chamber permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing. said drip chamber having a drip level above its lower end, a flow regulating clamp in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp.
2. An expendable unitary transfusion set assembly comprising a bag having flexible plastic outer walls and an intermediate flexible plastic wall peripherally sealed to the outer walls and dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shut-Oil, a filter within the blood chamber in the path of how of blood from the blood bottle to the blood chamber. a drain tube permanently sealed to and leading from the lower end or" the blood chamber, a drip chamber permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow regulating clamp in the dispensing tubing, a squeeze bulb pressure pump, a fitting in the pressure chamber for connection to said squeeze bulb for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said how regulating clamp.
3. An expendable unitary transfusion set assembly comprising a bag having flexible plastic outer walls and an intermediate flexible plastic wall dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shut-oil, a filter within the blood chamber in the path of How of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber, the upper end of the drain tube projecting slightly above the lower end of the blood chamber, a drip chamber permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow regulating clamp in the dispensing tubing, and a means for supplying 'liuid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp.
4. An expendable unitary transfusion set assembly comprising a bag having collapsible plastic outer walls and an intermediate plastic wall sandwiched between and sealed to the outer walls and dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a tube permanently sealed to and connected between the upper end of the blood chamber and a cannula for insertion in the stopper of a blood bottle, said tube including a shut-oil, a filter Within the blood chamber sealed to said tube and in the path of flow of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber, a drip chamber permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow adjusting clamp in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate limited by said flow adjusting clump.
5. An expendable unitary transfusion set assembly comprising a plastic bag having two collapsible chambers respectively on one and on the opposite side of a common flexible plastic wall shared by the chambers and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shutoll, an inlet tube and a shut-off in the tube through which the air in the blood chamber can be expelled by squeezing the chamber prior to closing the drain tube permanently sealed to and leading from the lower end of the blood chamber to dispensing tubing, flow indicating and regulating means in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating means.
6. An expendable unitary transfusion set assembly comprising a plastic bag having two collapsible chambers respectively on one and on the oppsite side of a common flexible plastic wall shared by the chambers and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamher to a blood bottle and including an inlet tube and a shut-off in the tube through which the air in the blood chamber can be expelled by squeezing the chamber prior to closing the shut-off, a drain tube permanently sealed to and leading from the lower end of the blood chamber, a drip chamber permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a filter in the path of flow of blood to the drip chamber, a flow regulating means in the dispensing tubing. and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating means.
7 An expendable unitary transfusion set assembly comprising a bag having flexible plastic outer walls and an intermediate flexible plastic wall dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shut-oil, a filter within the blood chamber in the path of flow of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber, a metering device permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, a flow regulating clamp in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp.
8. An expendable unitary transfusion set assembly comprising a bag having flexible plastic outer walls and an intermediate flexible plastic wall dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including a shut-off, a filter within the blood chamber in the path of flow of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber to dispensing tubing, a flow regulating device in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate con trollable by said flow regulating device.
9. An expendable unitary transfusion set assembly comprising a bag having collapsible plastic outer walls and an intermediate plastic Wall sandwiched between and sealed to the outer walls and dividing the bag into two chambers on opposite sides of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pres sure chamber, a tube permanently sealed to and connected between the upper end of the blood chamber and a cannula for insertion in the stopper of a blood bottle, said tube including a shut-off, a filter within the blood chamber in the path of flow of blood from the blood bottle to the blood chamber, a drain tube permanently sealed to and leading from the lower end of the blood chamber to dispensing tubing, a flow adjusting means in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate limited by said flow adjusting means.
19. An expendable unitary transfusion set assembly comprising a plastic bag having two collapsible chambers respectively on one and on the opposite side of a common flexible plastic wall shared by the chambers and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, means for connecting the blood chamber to a blood bottle and including an inlet tube and a shutoff in the tube through which the air in the blood chamber can be expelled by squeezing the chamber prior to closing the shut-oil, a drain tube permanently sealed to and leading from the lower end of the blood chamber, a flow indicator permanently sealed to and connected at its upper end to said drain tube and at its lower end to dispensing tubing, a filter in the path of flow of blood to the flow indicator, a flow regulating means in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating means.
11. A unitary transfusion set assembly comprising a bag having collapsible outer walls and an intermediate wall sandwiched between and sealed to the outer walls and dividing the bag into two chambers respectively on one and on the opposite side of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a cannula for insertion in the stopper of a blood bottle, a tube having its upper end connected to said cannula, a shut off clamp on said tube, a tubular filter having a closed lower end within the blood chamber and having an open upper end, means sealing the open upper end of the filter to the lower end of said tube whereby blood flowing from the tube into the blood chamber flows through said filter, a drain tube leading from the lower end of the blood chamber, a drip chamber connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow adjusting clamp in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate limited by said flow adjusting clamp.
12. A unitary transfusion set assembly comprising a bag having collapsible outer walls and an intermediate wall sandwiched between and sealed to the outer walls and dividing the bag into two chambers respectively on one and on the opposite side of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a cannula for insertion in the stopper of a blood bottle, a tube having its upper end connected to said cannula, a shut off clamp on said tube, a tubular filter having a closed lower end within the blood chamber and having an open upper end, means sealing the open upper end of the filter to the lower end of said tube whereby blood flowing from the tube into the blood chamber flows through said filter, a drain tube leading from the lower end of the blood chamber to dispensing tubing, a flow adjusting means in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate limited by said flow adjusting means.
13. A unitary transfusion set assembly comprising a bag having flexible outer walls and an intermediate flexible wall peripherally sealed to the outer walls and dividing the bag into two chambers respectively on one and on the opposite side of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a tube having at its upper end means for connecting to a hood bottle, a shut off clamp on said tube, a tubular filter having a closed lower end within the blood chamber and having an open upper end, means sealing the open upper end of the filter to the lower end of said tube whereby blood flowing from the tube into the blood chamber flows through said filter, a drain tube leading from the lower end of the blood chamber, a drip chamber connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow regulating clamp in the dispensing tubing, a squeeze bulb pressure pump, a fitting in the pressure chamber for connection to said squeeze bulb and supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp.
14. A unitary transfusion set assembly comprising a bag having flexible outer walls and an intermediate flexi ble wall dividing the bag into two chambers respectively on one and on the opposite side of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a tube having at its upper end means for connecting to a blood bottle, a shut oil. clamp on said tube, a tubular filter having a closed lower end within the blood chamber and having an open upper end, means sealing the open upper end of the filter to the lower end of said tube whereby blood flowing from the tube into the blood chamber flows through said filter, a drain tube leading from the lower end of the blood chamber, the upper end of the drain tube projecting slightly above the lower end of the blood chamber, a drip chamber connected at its upper end to said drain tube and at its lower end to dispensing tubing, said drip chamber having a drip level above its lower end, a flow regulating clamp in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp,
15. A unitary transfusion set assembly comprising a bag having flexible outer walls and an intermediate flexible wall dividing the bag into two chambers respectively on one and on the opposite side of the intermediate wall and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a tube having at its upper end means for connecting to a blood bottle, a shut off clamp on said tube, a tubular filter having a closed lower end within the blood chamber and having an open upper end, means sealing the open upper end of the filter to the lower end of said tube whereby blood flowing from the tube into the blood chamber flows through said filter, a drain tube leading from the lower end of the blood chamber, a metering device connected at its upper end to said drain tube and at its lower end to dispensing tubing, a flow regulating claim pin the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said flow regulating clamp.
16. A unitary transfusion set assembly comprising a bag having two collapsible chambers respectively on one and on the opposite side of a common flexible plastic wall shared by the chambers and out of communication with each other, one chamber being the blood chamber and the other chamber being the pressure chamber, a tube having at its upper end means for connecting to a blood bottle, a shut oil clamp on said tube, said tube having its lower end sealed to said blood chamber, a drain tube leading from the lower end of the blood chamber to dispensing tubing, flow indicating and regulating means in the dispensing tubing, and a means for supplying fluid under pressure to said pressure chamber to force the blood out of the blood chamber at a rate controllable by said fiow regulating means.
17. In an administration set, a blood bag having spaced flexible plastic walls, a plastic inlet tube having one end entering and sealed to the bag, [a shut-oil in the tube] said tube having associated shut-0]} means through which air may be expelled by squeezing the bag prior to closing the shut-oft, an outlet from the bag for conducting blood to a patient, another Wall outside and sealed at its edges to one of the Walls of the bag and forming therewith a pressure chamber external to the bag, and a pressure pump connected to said other Wall for developing a pressure on said one wall of the bag forcing blood under pressure out through said outlet.
18. The administration set ofclaim 17 having in addition a filter within the blood bag sealed to the entering end of the inlet tube.
19. The administration set ofclaim 17 in which the bag and pressure chamber comprise three sheets of flexible plastic arranged one on top of the other and sealed to each other around the peripheral edges, one of the outer sheets and the intermediate sheet comprising the blood bag, and the other of the outer sheets and the intermedi ate sheet comprising the pressure chamber.
2% The administration set ofclaim 17 in which the outlet comprises a plastic tube with one end entering and sealed to the bottom of the blood bag and projecting slightly above the bottom of the blood bag.
References Cited by the Examiner The following references, cited by the Examiner, are of record in the patented file of this patent or the original patent.
UNITED STATES PATENTS FOREIGN PATENTS 6/1957 Switzerland.
OTHER REFERENCES Walter et al.: A Closed Gravity Technique for the Preservation of Whole Blood in ACD Solution Utilizing Plastic Equipment, from Surgery, Gyne. and Obstet., vol. 94, #6, June 52, pages 687692.
RlCHARD A. GAUDET, Primary Examiner.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US861658AUS3054401A (en) | 1959-12-23 | 1959-12-23 | Transfusion set |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| USRE26006Etrue USRE26006E (en) | 1966-04-26 |
Family
ID=25336408
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US26006DExpiredUSRE26006E (en) | 1959-12-23 | Transfusion set | |
| US861658AExpired - LifetimeUS3054401A (en) | 1959-12-23 | 1959-12-23 | Transfusion set |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US861658AExpired - LifetimeUS3054401A (en) | 1959-12-23 | 1959-12-23 | Transfusion set |
Country Status (2)
| Country | Link |
|---|---|
| US (2) | US3054401A (en) |
| GB (1) | GB892875A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5891096A (en)* | 1996-08-20 | 1999-04-06 | Critical Device Corporation | Medicament infusion device |
| WO1999034848A1 (en)* | 1998-01-08 | 1999-07-15 | Nexell Therapeutics Inc. | Method, bag and disposable set for recirculation washing of blood cells |
| US6371732B1 (en) | 1998-11-09 | 2002-04-16 | Ahmad Maher Moubayed | Curvilinear peristaltic pump |
| US6551279B1 (en) | 2000-05-25 | 2003-04-22 | Oratec Interventions, Inc. | Infusion dispenser with adjustable flow rate regulator |
| US10967126B2 (en)* | 2011-04-28 | 2021-04-06 | Sanofi-Aventis Deutschland Gmbh | Joining technology of a dispense interface |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3228395A (en)* | 1961-11-10 | 1966-01-11 | Mcgaw Lab Inc | Blood bag transfusion unit with pressure chamber |
| US3153414A (en)* | 1962-02-02 | 1964-10-20 | Abbott Lab | Apparatus for the induced infusion of liquid from a flexible liquid container |
| US3640277A (en)* | 1968-12-09 | 1972-02-08 | Marvin Adelberg | Medical liquid administration device |
| US3709222A (en)* | 1970-12-28 | 1973-01-09 | Sarns Inc | Method and apparatus for automatic peritoneal dialysis |
| US4033345A (en)* | 1975-11-13 | 1977-07-05 | Sorenson Research Co., Inc. | Autologous transfusion filter system and method |
| US4270533A (en)* | 1977-08-16 | 1981-06-02 | Andreas Joseph M | Multiple chamber container for delivering liquid under pressure |
| US4214583A (en)* | 1979-03-09 | 1980-07-29 | Manoochehr Arfaa | Surgical wash system |
| US4382753A (en)* | 1979-03-09 | 1983-05-10 | Avi, Inc. | Nonpulsating IV pump and disposable pump chamber |
| US4332246A (en)* | 1980-06-30 | 1982-06-01 | Staodynamics, Inc. | Positive displacement intravenous infusion pump device and method |
| EP0077189B1 (en)* | 1981-10-09 | 1987-08-12 | Biofusion (Proprietary) Limited | An infusion unit |
| DE69124397T2 (en)* | 1991-09-12 | 1997-08-14 | Kyoraku Co Ltd | BLOW-MOLDED PLASTIC CONTAINER FOR LIQUID MEDICINE |
| US5318556A (en)* | 1993-04-09 | 1994-06-07 | Deknatel Technology Corporation | Fluid bag |
| DE19546028C2 (en)* | 1995-12-09 | 2000-04-27 | Fresenius Ag | Balancing disposable for balancing liquids for a medical treatment device and a medical treatment device with a system insert for receiving such a balancing disposable |
| US6210391B1 (en) | 1998-11-19 | 2001-04-03 | Genzyme Corporation | Rapid transfer autotransfusion bag and methods related thereto |
| US7188644B2 (en)* | 2002-05-03 | 2007-03-13 | Advanced Technology Materials, Inc. | Apparatus and method for minimizing the generation of particles in ultrapure liquids |
| US7048727B1 (en) | 2003-04-18 | 2006-05-23 | Gerald Moss | Continuous feeding and decompressing device and method |
| US20060270970A1 (en)* | 2003-04-18 | 2006-11-30 | Gerald Moss | Method and apparatus for suctioning and refeeding gastric juices |
| US20050224523A1 (en)* | 2004-04-13 | 2005-10-13 | Advanced Technology Materials, Inc. | Liquid dispensing method and system with headspace gas removal |
| US20050279207A1 (en)* | 2004-06-16 | 2005-12-22 | Advanced Technology Materials, Inc. | Liquid delivery system |
| CN103101867B (en)* | 2006-06-13 | 2017-07-28 | 恩特格里斯公司 | Fuid distribution system and method, connector, microelectronic product manufacturing equipment |
| CN105555382A (en)* | 2013-04-25 | 2016-05-04 | 离体动力学公司 | Non-hemolyzing blood filter and methods for filtering blood without hemolysis |
| CN114452477B (en)* | 2022-03-15 | 2025-07-15 | 北京大学第三医院（北京大学第三临床医学院） | A blood sampling and infusion device |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US972201A (en)* | 1909-11-11 | 1910-10-11 | Duplex Rubber Company | Syringe. |
| US1205410A (en)* | 1914-01-07 | 1916-11-21 | Alonzo C Tenney | Injection apparatus. |
| US2231418A (en)* | 1940-03-02 | 1941-02-11 | Lilly Co Eli | Liquid-administering apparatus |
| US2409734A (en)* | 1941-09-20 | 1946-10-22 | Swiss Firm Of G Laubscher & Co | Instrument for blood transfusion |
| US2848995A (en)* | 1949-07-06 | 1958-08-26 | Abbott Lab | Transfusion apparatus |
| US2702034A (en)* | 1950-07-20 | 1955-02-15 | Fenwal Inc | Apparatus for collecting, storing, and dispensing whole blood |
| US2907325A (en)* | 1953-11-27 | 1959-10-06 | R K Laros Company | Venoclysis equipment |
| US2766907A (en)* | 1955-03-15 | 1956-10-16 | Robbins Instr Corp | Pressure infusion apparatus |
| US2915063A (en)* | 1957-12-23 | 1959-12-01 | Cutter Lab | In-dwelling cannula |
- 0
- USUS26006Dpatent/USRE26006E/ennot_activeExpired
- 1959
- 1959-12-23USUS861658Apatent/US3054401A/ennot_activeExpired - Lifetime
- 1960
- 1960-10-31GBGB37286/60Apatent/GB892875A/ennot_activeExpired
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5891096A (en)* | 1996-08-20 | 1999-04-06 | Critical Device Corporation | Medicament infusion device |
| WO1999034848A1 (en)* | 1998-01-08 | 1999-07-15 | Nexell Therapeutics Inc. | Method, bag and disposable set for recirculation washing of blood cells |
| US6251295B1 (en) | 1998-01-08 | 2001-06-26 | Nexell Therapeutics Inc. | Method for recirculation washing of blood cells |
| US20010035377A1 (en)* | 1998-01-08 | 2001-11-01 | Nexell Therapeutics Inc. | Recirculation container |
| US6371732B1 (en) | 1998-11-09 | 2002-04-16 | Ahmad Maher Moubayed | Curvilinear peristaltic pump |
| US6551279B1 (en) | 2000-05-25 | 2003-04-22 | Oratec Interventions, Inc. | Infusion dispenser with adjustable flow rate regulator |
| US10967126B2 (en)* | 2011-04-28 | 2021-04-06 | Sanofi-Aventis Deutschland Gmbh | Joining technology of a dispense interface |
Also Published As
| Publication number | Publication date |
|---|---|
| US3054401A (en) | 1962-09-18 |
| GB892875A (en) | 1962-04-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| USRE26006E (en) | Transfusion set | |
| US4941875A (en) | I.V. system for successive administration of two or more solutions at different rates | |
| US4256104A (en) | Equipment sets and system for the sequential administration of medical liquids at dual flow rates | |
| US4653577A (en) | Unitary heat exchanger and debubbler for a liquid | |
| US4324238A (en) | Equipment sets having a combined air barrier and liquid sequencing device for the sequential administration of medical liquids at dual flow rates | |
| US4223695A (en) | Novel valve employing hydrophobic and hydrophilic membranes | |
| CA1127042A (en) | Valve employing hydrophobic and hydrophilic membranes | |
| US5207638A (en) | Blood transfer apparatus | |
| US4034754A (en) | Intravenous solution set having a constricted inner diameter portion | |
| US2693801A (en) | Safety cutoff valve for liquid administering apparatus | |
| EP0343286B1 (en) | Volumetric pump for parenteral perfusion | |
| US4316460A (en) | Gravitational flow system for the sequential administration of medical liquids | |
| US2989052A (en) | Parenteral fluid equipment | |
| US3965895A (en) | Apparatus for controlled volume and rate administration of liquids | |
| GB1459896A (en) | Cardiotomy reservoir | |
| US20160213861A1 (en) | Air stop membrane for maintaining a fluid column in an iv set | |
| US2664085A (en) | Venoclysis equipment | |
| US4413990A (en) | Air bypass valve assembly for a medical fluid administration set | |
| US4252116A (en) | Equipment sets having a novel flexible diaphragm valve in a secondary liquid flow path for the sequential administration of medical liquids at dual flow rates | |
| CA1148821A (en) | Equipment sets having reduced diameter primary tube for the sequential administration of medical liquids at dual flow rates | |
| US4186740A (en) | Method and apparatus for regulating intravenous flow of a liquid | |
| US4250879A (en) | Equipment sets and system for the sequential administration of medical liquids at dual flow rates employing a combined air barrier and liquid sequencing valve | |
| US4258712A (en) | Equipment sets having a pilot liquid controlled primary tube valve for the sequential administration of medical liquids at dual flow rates | |
| US4236515A (en) | Equipment sets and system for the sequential administration of medical liquids at dual flow rates employing parallel secondary liquid tubing | |
| US4237879A (en) | Equipment sets for the sequential administration of medical liquids at dual flow rates employing parallel secondary liquid tubing and a 3-way valve |