| US4201210A              (en)* | 1976-06-22 | 1980-05-06 | The United States Of America As Represented By The Secretary Of Agriculture | Veterinary ocular ring device for sustained drug release | 
| US4223022A              (en)* | 1978-01-16 | 1980-09-16 | Schering Corporation | Stabilized aminoglycoside antibiotic formulations | 
| US4298002A              (en)* | 1979-09-10 | 1981-11-03 | National Patent Development Corporation | Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation | 
| US4281654A              (en)* | 1980-04-07 | 1981-08-04 | Alza Corporation | Drug delivery system for controlled ocular therapy | 
| US4678466A              (en)* | 1981-06-25 | 1987-07-07 | Rosenwald Peter L | Internal medication delivery method and vehicle | 
| US4484922A              (en)* | 1981-06-25 | 1984-11-27 | Rosenwald Peter L | Occular device | 
| US4653483A              (en)* | 1982-11-12 | 1987-03-31 | Clavin Harold D | Cosmetic tape, applicator therefor and method | 
| US4524776A              (en)* | 1983-10-27 | 1985-06-25 | Withers Stanley J | Split carrier for eyelid sensor and the like | 
| US5322691A              (en)* | 1986-10-02 | 1994-06-21 | Sohrab Darougar | Ocular insert with anchoring protrusions | 
| US5147647A              (en)* | 1986-10-02 | 1992-09-15 | Sohrab Darougar | Ocular insert for the fornix | 
| US5989579A              (en)* | 1986-10-02 | 1999-11-23 | Escalon Medical Corp. | Ocular insert with anchoring protrusions | 
| US5098443A              (en)* | 1989-03-23 | 1992-03-24 | University Of Miami | Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents | 
| US5660851A              (en)* | 1989-12-26 | 1997-08-26 | Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem | Ocular inserts | 
| US5384333A              (en)* | 1992-03-17 | 1995-01-24 | University Of Miami | Biodegradable injectable drug delivery polymer | 
| US5178635A              (en)* | 1992-05-04 | 1993-01-12 | Allergan, Inc. | Method for determining amount of medication in an implantable device | 
| US5314419A              (en)* | 1992-10-30 | 1994-05-24 | Pelling George E | Method for dispensing ophthalmic drugs to the eye | 
| US5433714A              (en)* | 1993-04-06 | 1995-07-18 | Bloomberg; Leroy | Topical anesthesia method for eye surgery, and applicator therefor | 
| US5618274A              (en)* | 1994-04-08 | 1997-04-08 | Rosenthal; Kenneth J. | Method and device for deep pressurized topical, fornix applied "nerve block" anesthesia | 
| US5466233A              (en)* | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same | 
| US5472436A              (en)* | 1994-07-26 | 1995-12-05 | Fremstad; Daria A. | Ocular appliance for delivering medication | 
| US5601548A              (en)* | 1994-11-07 | 1997-02-11 | Ophthalmic International, L.L.C. | Open angle glaucoma treatment apparatus and method | 
| US5641749A              (en)* | 1995-11-29 | 1997-06-24 | Amgen Inc. | Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product | 
| US5641750A              (en)* | 1995-11-29 | 1997-06-24 | Amgen Inc. | Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product | 
| US6013122A              (en) | 1998-08-18 | 2000-01-11 | Option Technologies, Inc. | Tattoo inks | 
| EP2316394B1              (en) | 2001-06-12 | 2016-11-23 | The Johns Hopkins University | Reservoir device for intraocular drug delivery | 
| US20050004625A1              (en)* | 2001-06-29 | 2005-01-06 | Chow Alan Y. | Treatment of degenerative retinal disease via electrical stimulation of surface structures | 
| US20050033202A1              (en) | 2001-06-29 | 2005-02-10 | Chow Alan Y. | Mechanically activated objects for treatment of degenerative retinal disease | 
| US7031776B2              (en)* | 2001-06-29 | 2006-04-18 | Optobionics | Methods for improving damaged retinal cell function | 
| US20040247681A1              (en)* | 2001-08-07 | 2004-12-09 | Ellis Edward J. | Drug release system for controlled therapy | 
| EP1283025A1              (en)* | 2001-08-10 | 2003-02-12 | Stöckert Instrumente GmbH | Ballon occlusion device | 
| US7073507B2              (en)* | 2001-11-05 | 2006-07-11 | David Morris | Sterile ocular cover and method | 
| WO2005023181A2              (en)* | 2003-08-22 | 2005-03-17 | Vista Scientific | Polymeric systems for controlled drug therapy | 
| EP1658109B1              (en) | 2003-08-26 | 2014-01-22 | Vista Scientific LLC | Ocular drug delivery device | 
| WO2007024429A2              (en)* | 2005-08-19 | 2007-03-01 | Freedom-2, Llc | Cellular or organelle-entrapped nanoparticles | 
| US20080188416A1              (en)* | 2007-02-05 | 2008-08-07 | Freedom-2, Inc. | Tissue fillers and methods of using the same | 
| US9125807B2              (en)* | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery | 
| US10398594B2              (en) | 2007-10-04 | 2019-09-03 | Aciont, Inc. | Intrascleral drug delivery device and associated methods | 
| US8623395B2              (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device | 
| CN104887389B              (en) | 2009-01-29 | 2017-06-23 | 弗赛特影像4股份有限公司 | Posterior segment drug delivery | 
| CN102596097B              (en)* | 2009-06-03 | 2015-05-20 | 弗赛特实验室有限责任公司 | an eye insert | 
| US10166142B2              (en) | 2010-01-29 | 2019-01-01 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device | 
| LT2600930T              (en) | 2010-08-05 | 2021-04-12 | Forsight Vision4, Inc. | Injector apparatus for drug delivery | 
| US10617557B2              (en) | 2010-08-05 | 2020-04-14 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus | 
| PT2600812T              (en) | 2010-08-05 | 2021-11-09 | Forsight Vision4 Inc | Implantable therapeutic device | 
| WO2012068549A2              (en) | 2010-11-19 | 2012-05-24 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices | 
| US9119773B2              (en) | 2011-06-27 | 2015-09-01 | Board Of Regents, The University Of Texas System | Toroidal pharmaceutical formulations | 
| US10398592B2              (en) | 2011-06-28 | 2019-09-03 | Forsight Vision4, Inc. | Diagnostic methods and apparatus | 
| US9102105B2              (en) | 2011-09-13 | 2015-08-11 | Vista Scientific Llc | Method for forming an ocular drug delivery device | 
| CN103917202B              (en) | 2011-09-14 | 2016-06-29 | 弗赛特影像5股份有限公司 | Eye insert devices and methods | 
| HRP20210676T1              (en) | 2011-09-16 | 2021-05-28 | Forsight Vision4, Inc. | Fluid exchange apparatus | 
| JP5852449B2              (en)* | 2012-01-20 | 2016-02-03 | 原 裕 | Conjunctival sac fitting | 
| WO2013116061A1              (en) | 2012-02-03 | 2013-08-08 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices | 
| AU2013334169B2              (en) | 2012-10-26 | 2018-03-29 | Forsight Vision5, Inc. | Ophthalmic system for sustained release of drug to eye | 
| WO2014152959A1              (en) | 2013-03-14 | 2014-09-25 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant | 
| ES2972168T3              (en) | 2013-03-28 | 2024-06-11 | Forsight Vision4 Inc | Ophthalmic implant for administration of therapeutic substances | 
| WO2015066616A1              (en)* | 2013-11-04 | 2015-05-07 | Thompson Vance M | Conjunctival cover and methods therefor | 
| US9668916B2              (en) | 2013-11-04 | 2017-06-06 | Vance M. Thompson | Conjunctival cover and methods therefor | 
| ES2803102T3              (en) | 2014-07-15 | 2021-01-22 | Forsight Vision4 Inc | Eye implant delivery device | 
| WO2016022750A1              (en) | 2014-08-08 | 2016-02-11 | Forsight Vision4, Inc. | Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof | 
| WO2016031093A1              (en)* | 2014-08-28 | 2016-03-03 | 株式会社ユニバーサルビュー | Ocular insert device | 
| JP5643461B1              (en)* | 2014-08-28 | 2014-12-17 | 株式会社ユニバーサルビュー | Eyelid interior tools | 
| JP5671183B1              (en)* | 2014-08-28 | 2015-02-18 | 株式会社ユニバーサルビュー | Eyelid interior tools | 
| JP5643460B1              (en)* | 2014-08-28 | 2014-12-17 | 株式会社ユニバーサルビュー | Eyelid interior tools | 
| WO2016077371A1              (en) | 2014-11-10 | 2016-05-19 | Forsight Vision4, Inc. | Expandable drug delivery devices and method of use | 
| TW201642914A              (en)* | 2015-02-23 | 2016-12-16 | 組織科技股份有限公司 | Apparatuses and methods for treating ophthalmic diseases and disorders | 
| US9869883B2              (en) | 2015-03-11 | 2018-01-16 | Vance M. Thompson | Tear shaping for refractive correction | 
| EP3283004A4              (en) | 2015-04-13 | 2018-12-05 | Forsight Vision5, Inc. | Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent | 
| WO2016187426A1              (en) | 2015-05-19 | 2016-11-24 | Amorphex Therapeutics Llc | A device that delivers a sustained low-dose of a myopia-suppressing drug | 
| US11432959B2              (en) | 2015-11-20 | 2022-09-06 | Forsight Vision4, Inc. | Porous structures for extended release drug delivery devices | 
| MX2018012021A              (en) | 2016-04-05 | 2019-01-24 | Forsight Vision4 Inc | Implantable ocular drug delivery devices. | 
| US10353220B2              (en) | 2016-10-17 | 2019-07-16 | Vance M. Thompson | Tear shaping for refractive correction | 
| CN107224348B              (en)* | 2017-06-01 | 2020-05-05 | 佛山勃林格医疗器械有限公司 | Eye surface sustained-release drug delivery device and manufacturing method thereof | 
| AU2018372806B2              (en) | 2017-11-21 | 2024-05-30 | Forsight Vision4, Inc. | Fluid exchange apparatus for expandable port delivery system and methods of use | 
| US10678067B2              (en) | 2018-04-06 | 2020-06-09 | Vance M. Thompson | Tear shaping for refractive correction | 
| EP4048212A2              (en) | 2019-10-24 | 2022-08-31 | Denis E. Labombard | Ocular device and drug delivery system, with case | 
| USD1033637S1              (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |