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US8256653B2 - Surgical instrument with clamp - Google Patents

Surgical instrument with clamp
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US8256653B2
US8256653B2US13/194,168US201113194168AUS8256653B2US 8256653 B2US8256653 B2US 8256653B2US 201113194168 AUS201113194168 AUS 201113194168AUS 8256653 B2US8256653 B2US 8256653B2
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clamp
jaw members
respect
pair
surgical instrument
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David Farascioni
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Covidien LP
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Tyco Healthcare Group LP
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Abstract

A surgical instrument for surgically joining tissue is disclosed. The surgical instrument includes a handle portion, an endoscopic portion, a pair of jaw members and a clamp. The endoscopic portion extends distally from the handle portion and defines a longitudinal axis. The pair of jaw members is disposed adjacent a distal end of the endoscopic portion. At least one of the jaw members is movable with respect to the other between an open position and an approximated position for engaging body tissue therebetween. The pair of jaw members is curved with respect to the longitudinal axis. The clamp is disposed adjacent the jaw members. The clamp is movable between an open position and an approximated position for engaging body tissue. The clamp is independently movable with respect to the jaw members and is curved with respect to the longitudinal axis.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a Divisional of, claims the benefits of and priority to U.S. patent application Ser. No. 12/430,193 filed on Apr. 27, 2009, now U.S. Pat. No. 7,997,468, and claims the benefits of and priority to U.S. Provisional Patent Application Ser. No. 61/050,282 filed on May 5, 2008, the entire contents of each of which being herein incorporated by reference in its entirety.
BACKGROUND
1. Technical Field
The present disclosure relates generally to instruments for surgically joining tissue and, more specifically, to a surgical instrument having a clamp.
2. Background of Related Art
Various types of surgical instruments used to surgically join tissue are known in the art, and are commonly used, for example, for closure of tissue or organs in transection, resection, anastomoses, for occlusion of organs in thoracic and abdominal procedures, and for electrosurgically fusing or sealing tissue.
One example of such a surgical instrument is a surgical stapling instrument, which may include an anvil assembly, a cartridge assembly for supporting an array of surgical staples, an approximation mechanism for approximating the cartridge and anvil assemblies, and a firing mechanism for ejecting the surgical staples from the cartridge assembly.
Using a surgical stapling instrument, it is common for a surgeon to approximate the anvil and cartridge members. Next, the surgeon can fire the instrument to emplace staples in tissue. Additionally, the surgeon may use the same instrument or a separate instrument to cut the tissue adjacent or between the row(s) of staples.
Other examples of a surgical instrument of the present disclosure include electrosurgical (e.g., monopolar and bipolar) forceps. Electrosurgical forceps utilize both mechanical clamping action and electrical energy to affect hemostasis by heating the tissue and blood vessels to coagulate, cauterize and/or seal tissue.
SUMMARY
The present disclosure relates to a surgical instrument for surgically joining tissue. The surgical instrument includes a handle portion, an elongated portion, a pair of jaw members and a clamp. The elongated portion extends distally from the handle portion and defines a first longitudinal axis. The pair of jaw members is disposed adjacent a distal end of the elongated portion. At least one of the jaw members is movable with respect to the other between an open position and an approximated position for engaging body tissue therebetween. The clamp is disposed adjacent the jaw members and extends generally distally from the elongated portion. The clamp is movable between an open position and an approximated position for engaging body tissue. The clamp is independently movable with respect to the jaw members.
In a disclosed embodiment, the clamp includes a first portion and a second portion and at least one portion of the clamp is pivotable with respect to the other portion about a pivot point disposed at a proximal portion of the clamp. In another disclosed embodiment, each of the jaw members is substantially parallel to the clamp.
In embodiments of the surgical instrument, the jaw members include an anvil assembly and a cartridge assembly, or are configured to deliver electrosurgical energy to tissue. In disclosed embodiments, the jaw members are curved with respect to the first longitudinal axis and/or the clamp is curved with respect to the first longitudinal axis. In further disclosed embodiments, the jaw members are rotatable with respect to the handle portion, about the first longitudinal axis.
In a disclosed embodiment, the jaw members are part of a loading unit and the loading unit is attachable to the elongated portion.
In an embodiment, the end effector defines a second longitudinal axis. Here, the end effector is movable from a first position where the second longitudinal axis is substantially aligned with the first longitudinal axis to at least a second position where the second longitudinal axis is disposed at an angle to the first longitudinal axis.
The present disclosure also relates to a loading unit configured for releasable engagement with a surgical instrument. The loading unit includes a body portion, a pair of jaw members, and a clamp. The body portion defines a first longitudinal axis. A proximal portion of the body portion is configured for releasable engagement with an elongated portion of the surgical instrument. The pair of jaw members is disposed distally of the body portion. At least one of the jaw members is movable with respect to the other between an open position and an approximated position for engaging body tissue therebetween. The clamp is disposed adjacent the jaw members and is movable between an open position and an approximated position for engaging body tissue. The clamp is independently movable with respect to the jaw members.
In a disclosed embodiment, the clamp of the loading unit includes a first portion and a second portion and at least one portion of the clamp is pivotable with respect to the other portion about a pivot point disposed at a proximal portion of the clamp.
In an embodiment, each of the jaw members is substantially parallel to the clamp. Embodiments of the loading unit also include jaw members that include an anvil assembly and a cartridge assembly or jaw members that are configured to deliver electrosurgical energy to tissue. Embodiments also include jaw members that are curved with respect to the first longitudinal axis and/or a clamp that is curved with respect to the first longitudinal axis.
The present disclosure also relates to a loading unit configured for releasable engagement with a surgical instrument, the loading unit including a pair of jaw members, and a clamp, and being configured for releasable engagement with an elongated portion of the surgical instrument. At least one of the jaw members is movable with respect to the other between an open position and an approximated position for engaging body tissue therebetween. The clamp is disposed adjacent the jaw members and is movable between an open position and an approximated position for engaging body tissue. The loading unit has a first mechanism for actuating the jaw members and a closing mechanism for the clamp.
In certain embodiments, the closing mechanism includes a clamp link. The clamp link may extend proximally to engage an instrument link on the surgical instrument upon engagement of the loading unit with the elongated portion of the surgical instrument. In certain embodiments, the first mechanism is arranged to move the jaw members between the open and approximated positions of the jaw members. In another embodiment, the first mechanism is arranged to fire staples from at least one of the jaw members.
The present disclosure also relates to a surgical instrument for joining tissue where the surgical instrument includes a handle portion, an elongated portion extending distally from the handle portion and defining a longitudinal axis, a pair of jaw members disposed adjacent a distal end of the endoscopic portion, at least one of the jaw members being movable with respect to the other of the jaw members between an open position and an approximated position for engaging body tissue therebetween, and a clamp disposed adjacent the jaw members and being movable between an open position and an approximated position for engaging body tissue, the jaw members being curved.
In certain embodiments, the jaw members are curved and have a convex side and a concave side, the clamp being disposed adjacent the concave side of the jaw members. The clamp may be curved or have a shape that corresponds to the curved jaw members.
The present disclosure also relates to a method of surgically joining tissue. The method includes the steps of providing a surgical instrument, moving a clamp of the surgical instrument from an open position towards an approximated position to engage body tissue, moving at least one of the jaw members of the surgical instrument with respect to the other from an open position towards an approximated position to engage body tissue, and actuating the jaw members to join tissue. The surgical instrument used in the disclosed method includes a handle portion, an elongated portion, a pair of jaw members and a clamp. The elongated portion extends distally from the handle portion. The pair of jaw members is disposed adjacent a distal end of the elongated portion and at least one of the jaw members is movable with respect to the other between an open position and an approximated position for engaging body tissue therebetween. The clamp is disposed adjacent the jaw members. The clamp is independently movable with respect to the jaw members.
Embodiments of the surgical instrument used in the disclosed method include jaw members having a cartridge assembly and an anvil assembly. Other embodiments of the surgical instrument used in the disclosed method include jaw members that are configured to deliver electrosurgical energy to tissue.
Embodiments of the disclosed method include identifying a portion of intestinal tissue to be joined, the intestinal tissue having an interior, clamping intestinal tissue adjacent the identified portion of intestinal tissue with a clamp of a surgical instrument, washing out or otherwise cleansing the interior of the intestinal tissue so as to include the identified portion of intestinal tissue, approximating jaw members of the surgical instrument to engage the identified portion of intestinal tissue, the jaw members being disposed adjacent the clamp on the surgical instrument, firing staples from at least one of the jaw members.
In certain embodiments, the tissue is joined by delivering ultrasonic or electrosurgical energy to the tissue. After being joined, the tissue may be cut using a blade disposed on the surgical instrument, or disposed on a separate instrument.
BRIEF DESCRIPTION OF FIGURES
Various embodiments of the presently disclosed surgical instrument are disclosed herein with reference to the drawings, wherein:
FIG. 1A is a perspective view of a surgical stapling instrument in accordance with the present disclosure;
FIG. 1B is a perspective view of an electrosurgical forceps in accordance with the present disclosure;
FIGS. 2-4 are perspective views of a loading unit, at various stages of operation, for use with the surgical instruments ofFIGS. 1A and 1B;
FIGS. 5 and 6 are perspective views of the loading unit ofFIGS. 2-4, illustrating a closing mechanism for use with a clamp;
FIG. 7 is a side view of the loading unit ofFIGS. 5 and 6;
FIG. 8 is a bottom view of the loading unit ofFIGS. 5-7; and
FIG. 9 is another side view of the loading unit ofFIGS. 5-8.
DETAILED DESCRIPTION
Embodiments of the presently disclosed surgical instrument, and loading unit for use therewith, are described in detail with reference to the drawings, wherein like reference numerals designate corresponding elements in each of the several views.
A surgical stapling instrument of the present disclosure is indicated asreference numeral100ainFIG. 1A. An electrosurgical forceps of the present disclosure is indicated asreference numeral100binFIG. 1B. Collectively,surgical instruments100aand100bare referred to herein as reference numeral100. Similarly, several features that are common to bothsurgical stapling instrument100aandelectrosurgical forceps100bare collectively referred to as the same reference number (e.g.,endoscopic portion110,jaw members220 and clamp230).
A loading unit (or “DLU”)200afor use with surgical instrument100 is shown inFIGS. 2-9.DLU200ais attachable to an elongated orendoscopic portion110 of surgical instrument100, e.g., to allow surgical instrument100 to have greater versatility.DLU200amay be configured for a single use, and/or may be configured to be used more than once.Surgical stapling instrument100aillustrated inFIG. 1A is shown with adifferent DLU200bfor illustrative purposes.Electrosurgical forceps100billustrated inFIG. 1B is shown without a DLU, in accordance with an embodiment of the present disclosure.
Examples of loading units for use with a surgical stapling instrument are disclosed in commonly-owned U.S. Pat. No. 5,752,644 to Bolanos et al., the entire contents of which are hereby incorporated by reference herein. Further details of an endoscopic surgical stapling instrument are described in detail in commonly-owned U.S. Pat. No. 6,953,139 to Milliman et al., the entire contents of which are hereby incorporated by reference herein. Further details of electrosurgical forceps are described in commonly-owned patent application Ser. No. 10/369,894, filed on Feb. 20, 2003, entitled VESSEL SEALER AND DIVIDER AND METHOD OF MANUFACTURING THE SAME, the entire contents of which are hereby incorporated by reference herein.
Referring now toFIGS. 2-9,DLU200aof the present disclosure is shown.DLU200aincludes aproximal portion210, a pair ofjaw members220, and aclamp230.Proximal portion210 is configured to removably attach to the elongated portion orendoscopic portion110 of surgical instrument100 (seeFIG. 1A) using a variety of attachment features, such as, for example, a bayonet coupling, latch, detent or snap-fit.
The present disclosure also relates to a surgical instrument100 having a distal portion that includes the features shown inFIGS. 2-9, where the distal portion (includingjaw members220 and clamp230) is fixedly attached to the endoscopic portion (i.e., not part of a DLU). Accordingly, the features of the DLU described herein may also be included onsurgical stapling instrument100aand/orelectrosurgical forceps100bwithout a removable or replaceable loading unit.
When used in connection withsurgical stapling instrument100a, thejaw members220 include acartridge assembly222 and an anvil assembly224 (cartridge assembly and anvil assembly are shown with reference numbers inFIG. 2 for illustrative purposes, but can be in opposite positions than shown without departing from the scope of this disclosure). Cartridge assembly houses a plurality of staples or fasteners (not explicitly shown in the embodiments ofFIGS. 2-9).Cartridge assembly222 includes a plurality of staple pushers for ejecting the staples therefrom. The DLU may include a plurality of cam bars for interacting with the pushers to deploy the surgical fasteners. For example, the apparatus disclosed in U.S. Pat. No. 5,318,221, the disclosure of which is hereby incorporated by reference herein, in its entirety, has a cam bar adapter that holds a plurality of cam bars and a knife. A channel is advanced through operation of the handle of the apparatus, which drives the cam bars and knife forward. A clamp tube that surrounds the proximal end of the anvil is advanced to clamp the anvil and cartridge together. In another example, the apparatus disclosed in U.S. Pat. No. 5,782,396, the disclosure of which is hereby incorporated by reference herein, in its entirety, has an actuation sled. An elongated drive beam is advanced distally through operation of the handle of the apparatus, driving the actuation sled forward. The distal end of the drive beam engages the anvil and the channel that supports the cartridge as the drive beam travels distally, to deploy the staples and clamp the anvil and cartridge together.
Anvil assembly224 includes staple pockets (not explicitly shown in the embodiments ofFIGS. 2-9) that are configured to form the staples as they are driven fromcartridge assembly222. Aclamp230 is mountedadjacent cartridge assembly222 andanvil assembly224 and is movable with respect toproximal portion210 to clamp tissue.Clamp230 includes afirst portion232 and a second portion234 (seeFIG. 5). At least one offirst portion232 andsecond portion234 ofclamp230 is movable with respect to the other.
When used in connection withelectrosurgical forceps100b, thejaw members220 mutually cooperate to grasp, seal and, in some cases, divide tubular vessels and vascular tissues.Electrosurgical forceps100bis usable with various electrosurgical procedures and generally includes ahousing20, ahandle assembly30, a rotatingassembly80, atrigger assembly70, andjaw members220.Electrosurgical forceps100balso includes aclamp230 adjacent itsjaw members220 to clamp the vessel or tissue prior to approximating the jaw members and prior to delivering energy thereto. Additionally,electrosurgical forceps100bincludes anelectrosurgical cable310 that connects theelectrosurgical forceps100bto a source of electrosurgical energy, e.g., a generator.
With specific reference toFIGS. 2-6 and8,jaw members220 are curved relative to a longitudinal axis A-A defined by endoscopic portion110 (FIGS. 1A and 1B). As shown, thejaw members220 of this embodiment extend generally distally from the endoscopic portion. It is envisioned that curved jaw members200 may facilitate performing certain types of surgical procedures. For example, curved jaw members200, as compared to straight jaw members (such as the jaw members illustrated inFIG. 1A), may help facilitate access to lower pelvis regions, e.g., during lower anterior resection (“LAR”). Additionally, the inclusion ofcurved jaw members220 may allow increased visualization to a surgical site and may also allow more room for a surgeon to manipulate target tissue or thejaw members220 themselves with his or her hand. It is desirable thatclamp230 is also curved, or thatclamp230 andjaws220 are parallel in the sense thatclamp230 andjaws220 do not converge or diverge from each other. As shown inFIG. 2, thejaw members220 have aconcave side220aand aconvex side220b. Theclamp230 is curved or shaped to correspond to thejaw members220. The clamp is disposed adjacent theconcave side220aof thejaw members220. In other embodiments, the clamp is disposed on theconvex side220bof the jaw members. Other shapes for the jaw members and clamp may be used to improve accessibility in the body, such as angled jaw members and/or clamp. To allow even more flexibility in positioningjaw members220 and clamp230 (e.g., within lower pelvis regions), surgical instrument100 may include a rotation feature (e.g., arotation dial120 inFIG. 1A or rotatingassembly80 inFIG. 1B) to help enable rotation ofjaw members220 and clamp230 with respect to a handle portion of surgical instrument100.
In a surgical stapling instrument in accordance with the present disclosure, a rod or other member is moved distally, through operation of the handle, to actuate the DLU and deploy the staples. For example, referring back toFIG. 1A, at least a partial actuation ofmovable handle132 with respectstationary handle130 translates a drive beam (not explicitly shown in the illustrated embodiments) longitudinally to approximate at least one jaw member with respect to the other. Additionally, at least a partial actuation (e.g., continued actuation) ofmovable handle132 translates a firing rod (not explicitly shown in the illustrated embodiments) longitudinally to eject surgical fasteners (e.g., staples) from cartridge assembly170 and/or to advance a knife to cut tissue. It is also envisioned that first handle approximates the jaw members with respect to one another and actuation of a second handle and/or a third handle causes the ejection of fasteners and advancement of the knife. Other types of handles can be used such as, for example, motor-driven, hydraulic, ratcheting, etc.
With continued reference toFIG. 1A, a lever140 is shown adjacent rotation dial120 and may be used to facilitate articulation of thejaw members220. Actuation of lever140 causes thejaw members220 to move between a first position, where thejaw members220 are substantially aligned with the longitudinal axis A-A, and a second position, where thejaw members220 are disposed at an angle with respect to the longitudinal axis A-A. It is envisioned that moving lever140 causes an articulation link to move longitudinally, which results in a proximal portion of at least one jaw member moving proximally or distally. That is, moving the lever140 in a first direction causes the articulation link to move proximally (which articulates thejaw members220 in a first direction) and moving the lever140 in a second, opposite direction causes the articulation link to move distally (which articulates thejaw members220 in a second direction).
Clamp230 is shown inFIGS. 2-9. In a disclosed embodiment, clamp230 is used to compress tissue betweenfirst portion232 andsecond portion234 thereof. It is envisioned that a user may position clamp230 on a proximal side of jaw members220 (and subsequent staple line or seal line), which may facilitate rectal washout.
As shown inFIGS. 2-4, a user actuatesclamp230 separately from actuatingjaw members220. In a contemplated use in connection withsurgical stapling instrument100a, a user first positions DLU200aabout tissue (withclamp230 andjaw members220 in an open position, as shown inFIG. 2). Next, the user causes clamp230 to compress the tissue (FIG. 3) and subsequently closes the jaw members220 (FIG. 4). After thejaw members220 are closed in a desired position, the user may then staple tissue (e.g., sequentially) and/or cut tissue.
In a contemplated use in connection withelectrosurgical forceps100b, a user firstpositions jaw members220 about tissue (withclamp230 andjaw members220 in an open position as shown inFIG. 2). Next, the user causes clamp230 to compress (FIG. 3) and subsequently closes the jaw members220 (FIG. 4). After thejaw members220 are closed in a desired position, the user may then depresstrigger assembly70 to deliver energy to the tissue to seal or coagulate the tissue. The user may cut tissue during the sealing/coagulation or thereafter.
As can be appreciated, there are several ways the various actuations of surgical instrument100 can be achieved. For example, surgical instrument100 may include a stationary handle, a clamp handle, first movable handle, a second movable handle and a release button. It is further envisioned that a release button can be actuated to release clamp230 (e.g., from a locked position). One or more movable handles are provided on the surgical instrument100 to affect closure ofclamp230, closure of thejaw members220, and firing of staples or delivering energy to tissue.
Other methods of actuating the surgical instrument100 are also envisioned. For example, whenDLU200ais used withsurgical stapling instrument100aofFIG. 1a, actuation ofmovable handle132 may closejaw members220, fire staples and/or cut tissue, and actuation of lever140 can be used to operateclamp230. Additionally, handleportion130 may include a single movable handle that may be squeezed multiple times, where each actuation can perform a distinct operation. That is, a first actuation of the movable handle may actuateclamp230, a second actuation of the movable handle may approximate thejaw members220, and a third actuation of the same movable handle may deploy staples and/or a knife or may deliver energy to the tissue.
Referring now toFIGS. 5 and 6, aclosing mechanism240 for approximatingclamp230 is shown.Closing mechanism240 includes apin242 and anangled slot244.Pin242 is disposed on a clamp link ofDLU200aor surgical instrument100 (not part of clamp230).Slot244 is shown disposed onfirst portion232 ofclamp230. As can be appreciated with reference toFIGS. 5 and 6, actuation ofclamp230 utilizing lever140 moves articulation link of surgical instrument100. The articulation link is connected to clamp link whenDLU200ais connected to instrument100. Movement of the clamp link causes relative movement betweenpin242 andslot244. That is, proximal movement ofpin242 relative to slot244 causesfirst portion232 ofclamp230 to move (e.g., cam, pivot, etc.) towardssecond portion234 ofclamp230. Any suitable structure may be incorporated with surgical instrument100 and/or DLU200ato cause the relative movement betweenpin242 andslot244. For example, surgical instrument100 may include a clamp collar that is longitudinally movable upon actuation of a movable handle/knob/etc. In such an embodiment, distal translation of clamp collar may camfirst portion232 relative tosecond portion234, and thus toapproximate clamp230. Additionally, proximal translation of clamp collar may openclamp230. Additionally, as shown inFIGS. 2-4,closing mechanism240 may be contained (or at least partially contained) within ahousing246, e.g., to help prevent undesired pinching of tissue.
Additionally, with reference back toFIG. 2, an embodiment of the present disclosure includes atab250 disposed onclamp230. (InFIG. 2, for example,tab250 is shown onsecond portion234 of clamp.) It is envisioned thattab250 is configured to mate with an aperture251 (shown in phantom inFIG. 2) disposed on the opposite portion of the clamp230 (e.g., the first portion232) whenclamp230 is in a closed position. Thistab250/aperture combination may help maintainclamp230 in a closed position and may also help maintain alignment of theportions232,234 ofclamp230 during use.
In a further embodiment, the jaw members and/or clamp are pivotally connected to theproximal portion210 of the DLU. The DLU includes the clamp link and an articulation link, each of which engage a corresponding link in the elongated portion of the surgical instrument100 upon engaging the DLU with the elongated portion. The handle portion of the instrument100 includes any combination of levers, slides, buttons, pivotable handles, etc., for separately actuating the jaw members, clamp and pivoting (also known as articulation) of the jaw members and/or clamp with respect to theproximal portion210 and elongated portion of the surgical instrument. An articulating loading unit for an endoscopic surgical stapler is disclosed in U.S. Pat. No. 6,953,139 to Milliman et al., the entire contents of which are hereby incorporated by reference herein, in its entirety.
The present disclosure also relates to a method of using the described surgical instrument100 and DLU200a. The method, as described above, includes providing surgical instrument100, clamping tissue viaclamp230, approximatingjaw members220, firing staples (e.g., sequentially) or delivering energy to the tissue, and/or cutting tissue (e.g., with a knife disposed in mechanical cooperation withDLU200aor surgical instrument100, or using a separate instrument). In certain embodiments,clamp230 is actuated, clamping onto intestinal tissue. Then, the interior of the intestinal tissue is washed out or otherwise cleansed. The tissue is then cut and stapled or joined using electrosurgical energy. In this way, the interior intestinal tissue is cleansed up to the location of the clamp, including the area where the jaws will engage the intestinal tissue to be stapled and/or cut, once the jaws are approximated.
While the above description contains many specifics, these specifics should not be construed as limitations on the scope of the present disclosure, but merely as illustrations of various embodiments thereof. Therefore, the above description should not be construed as limiting, but merely as exemplifications of various embodiments. Those skilled in the art will envision other modifications within the scope and spirit of the claims appended hereto.

Claims (18)

1. A surgical instrument for surgically joining tissue, comprising:
a handle portion;
an endoscopic portion extending distally from the handle portion and defining a longitudinal axis;
a pair of jaw members disposed adjacent a distal end of the endoscopic portion, at least one of the jaw members being movable with respect to the other between an open position and an approximated position for engaging body tissue therebetween, the pair of jaw members being curved with respect to the longitudinal axis; and
a clamp disposed adjacent the pair of jaw members and being mechanically coupled to at least one of the endoscopic portion and the pair of jaw members, the clamp being movable between an open position and an approximated position for engaging body tissue, the clamp being independently movable with respect to the jaw members, and the clamp being curved with respect to the longitudinal axis.
10. A loading unit configured for releasable engagement with a surgical instrument, the loading unit comprising:
a body portion defining a first longitudinal axis, a proximal portion of the body portion configured for releasable engagement with an endoscopic portion of the surgical instrument;
a pair of jaw members disposed distally of the body portion, at least one of the jaw members being movable with respect to the other between an open position and an approximated position for engaging body tissue therebetween, the pair of jaw members being curved with respect to the first longitudinal axis; and
a clamp disposed adjacent the jaw members and being mechanically coupled to at least one of the body portion and the pair of jaw members, the clamp being movable between an open position and an approximated position for engaging body tissue, and wherein the clamp is independently movable with respect to the jaw members.
US13/194,1682008-05-052011-07-29Surgical instrument with clampExpired - Fee RelatedUS8256653B2 (en)

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US12/430,193US7997468B2 (en)2008-05-052009-04-27Surgical instrument with clamp
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EP2116193A1 (en)2009-11-11
EP3178414B1 (en)2018-08-22
CN101574272B (en)2014-04-09
AU2009201761B2 (en)2014-07-03
CN101574272A (en)2009-11-11
JP2014028298A (en)2014-02-13
JP2010000341A (en)2010-01-07
CA2664876A1 (en)2009-11-05
US20110284614A1 (en)2011-11-24
ES2689912T3 (en)2018-11-16
EP2116193B1 (en)2019-03-20
US7997468B2 (en)2011-08-16
AU2009201761A1 (en)2009-11-19
EP3178414A1 (en)2017-06-14
ES2721445T3 (en)2019-07-31
US20090272784A1 (en)2009-11-05

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