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US3899011A - Disc dispenser - Google Patents

Disc dispenser
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US3899011A
US3899011AUS496287AUS49628774AUS3899011AUS 3899011 AUS3899011 AUS 3899011AUS 496287 AUS496287 AUS 496287AUS 49628774 AUS49628774 AUS 49628774AUS 3899011 AUS3899011 AUS 3899011A
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United States
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plate
disc
dispensing
dispenser
set forth
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US496287A
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Alan C Curtiss
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Warner Lambert Co LLC
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Pfizer Corp Belgium
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Priority claimed from US00281946Aexternal-prioritypatent/US3832532A/en
Application filed by Pfizer Corp BelgiumfiledCriticalPfizer Corp Belgium
Priority to US496287ApriorityCriticalpatent/US3899011A/en
Priority to CA220,109Aprioritypatent/CA1008029A/en
Priority to GB6868/75Aprioritypatent/GB1496015A/en
Priority to IL46660Aprioritypatent/IL46660A/en
Priority to SE7502000Aprioritypatent/SE412890B/en
Priority to AU78495/75Aprioritypatent/AU491178B2/en
Priority to AR257731Aprioritypatent/AR211094A1/en
Priority to FI750533Aprioritypatent/FI58306C/en
Priority to NL7502269Aprioritypatent/NL7502269A/en
Priority to DE2508820Aprioritypatent/DE2508820C2/en
Priority to DK80275AAprioritypatent/DK139928B/en
Priority to BE1006487Aprioritypatent/BE826106A/en
Priority to FR7506349Aprioritypatent/FR2281297A1/en
Priority to CH257675Aprioritypatent/CH590926A5/xx
Priority to IT48387/75Aprioritypatent/IT1029895B/en
Priority to ES435228Aprioritypatent/ES435228A1/en
Priority to JP50025862Aprioritypatent/JPS5756349B2/ja
Priority to BR1230/75Aprioritypatent/BR7501230A/en
Publication of US3899011ApublicationCriticalpatent/US3899011A/en
Application grantedgrantedCritical
Assigned to WARNER-LAMBERT COMPANY, A CORP. OF DE.reassignmentWARNER-LAMBERT COMPANY, A CORP. OF DE.ASSIGNMENT OF ASSIGNORS INTEREST.Assignors: PFIZER INC.
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Abstract

A number of antimicrobial impregnated discs are simultaneously dispensed into separate chambers of a partitioned cuvette, each containing a suspension of a bacterial broth, to determine which antimicrobial, antibacterial or antibiotic is the most suitable for treating the affected patient. The disc dispenser has a line of dispensing chutes disposed above the open tops of the cuvette chambers and a mechanism for receiving a disc from each of a line of supply tubes and dropping it into the dispensing chute. The upper ends of the dispensing chutes are open to permit visual confirmation that a disc has been discharged through each of the chutes. The dispensing mechanism may comprise an apertured sliding plate which may be unitary or divided in an array of individual dispensers. It is incorporated in a dispensing table on a hollow fixture which receives the cuvette. The fixture may include a pair of end sections and an operating plunger may be mounted in one of them.

Description

United States Patent Curtiss Aug. 12, 1975 [54] DISC DISPENSER Primary ExaminrHouston S. Bell, Jr [75] Inventor. Alan C. Curtiss, Old Lyme, Conn. I n y g n or connony and Hutz [73] Assignee: Pfizer Inc., New York, NY. g 22 Filed: Aug. 9, 1974 [57] ABSTRACT A number of antimicrobial impregnated discs are si- [21] Appl' 496287 multaneously dispensed into separate chambers of a Related US. Application Data partitioned cuvette, each containing a suspension of a [63] continuatiomimpan of Ser No. 281,946 Aug 18, bacterial broth, -to determine which antimicrobial, 1972, Pat No 33321532 antibacterial or antibiotic is the most suitable for treating the affected patient. The disc dispenser has a s2 U.S. c1. 141/325; 195/127; 221/93; line of dispensing Chutes disposed above thep p 222/362 of the cuvette chambers and a mechanism for receiv- 51 1111.01B65b 1/04;B65b 3/04 ing a disc from each of a line of Snpply tubes and [58] Field of Search 221/93, 198, 279; 133/4 R, dropping it into the dispensing chine- The pp ends 133 5 R, 5 137 2 5; 23 259; 14 00 of the dispensing chutes are open to permit visual con- 83, 241, 237, 273, 319422 325, 326 firmation that a disc has been discharged through each 3 34, 2 4; 195 03 20 2 of the chutes. The dispensing mechanism may com- 222 132 134 13 139 362, 442 prise an apertured sliding plate which may be unitary or divided in an array of individual dispensers. It is in- 5 References Cited corporated in a dispensing table on a hollow fixture UNITED STATES PATENTS which receives' the cuvette. The fixture may include a 3 300 087 H yp 221/93 pa1r of end sections and an operating plunger may be 3:304:965 2/1967 Tate 141 325 mounted m one of them" 3,372,7l7 3/1968 Fisher 141/325 21 Claims, 21 Drawing Figures 1 r gh-r l mei mq' ll'lia lllii PATENTEDAUGI 2% 3,899,611
DISC DISPENSER CROSS-REFERENCE TO RELATED APPLICATION, IF ANY This application is a continuation-in-part of copending commonly assigned patent applications for US. Letters Patent: Ser. No. 281,946 filed Aug. 18, 1972, now US. Pat. No. 3,832,532, by this same inventor in conjunction with three other inventors who were coinventors of other portions of the invention disclosed and claimed therein but not the disc dispenser portion being disclosed and claimed herein and Ser. No. 437,700 filed .Ian. 29, 1974, by this same inventor.
BACKGROUND OF THE INVENTION Mechanisms for dispensing antibiotic saturated discs from tubular cartridges are described in US. Pat. Nos. 3,031,819, 3,032,179, 3,036,703 and 3,115,992 and Canadian Pat. No. 687,149. Some of these dispensers simultaneously drop a number of discs into a culture dish or into separate compartments of solutions for comparing the effectiveness of the different antibiotics. Such multiple disc dispensers are subject to malfunctions which are significant because the failure to discharge even only one of the array of discs ruins the test. An object of this invention is, therefore, to provide a multiple disc dispenser'for dispensing into anarray of sample solutions, which is dependable in operation and in which malfunctions may be readily detected and corrected.
SUMMARY A number of antimicrobial impregnated discs are simultaneously dispensed into separate chambers of a partitioned cuvette, each containing a suspension of a bacterial broth, to determine which antimicrobial, antibacterial or antibiotic is the most suitable for treating the affected patient. The disc dispenser has a line of dispensing chutes disposed above the open tops of the cuvette chambers and a mechanism for receiving a disc from each of a line of supply tubes and dropping it into the dispensing chute. The upper ends of the dispensing chutes are open to permit visual confirmation that a disc has been discharged through each of the chutes. The dispensing mechanism may comprise an apertured sliding plate which may be unitary or divided in an array of individual dispensers. It is incorporated in a dispensing table on a hollow fixture which receives the cuvette. The fixture may include a pair of end sections and an operating plunger may be mounted in one of them. The bodies of the individual dispensers may be alternately directed to provide space between them for the actuating mechanism. A pair of sliding plates may be provided in the dispensing table for locking the individual dispensers in their recesses and actuating them by an inclined cam surface. The locking plate lugs may provide a limit of travel for protecting the dispenser pms.
BRIEF DESCRIPTION OF THE DRAWINGS Novel features and advantages of the present invention will become apparent to one skilled in the art from a reading of the following description in conjunction with the accompanying drawings wherein similar reference characters refer to similar parts and in which:
FIG. I is a top plan view of a disc dispenser which is one embodiment of this invention, showing several of its complement of individual disc dispensers installed in it;
FIG. 2 is a front elevational view of the disc dispenser shown in FIG. 1 holding a compartmented cuvette for receiving dispensed discs;
FIG. 3 is a cross-sectional view taken through FIG. 1 along theline 33;
FIG. 4 is a cross-sectional view taken through FIG. 1 along the line 4-4;
FIG. 5 is a cross-sectional view taken through FIG. 3 along the line 5-5 in the unlocked nondispensing condition;
FIG. 6 is a fragmental cross-sectional view of a portion of FIG. 5 in the locked position;
FIG. 7 is a cross-sectional view similar to FIG. 5 in the dispensing position;
FIG. 8 is a side view in elevation of one of the individual dispensers incorporated in the embodiment shown in FIG. 1;
FIG. 9 is a top plan view of the individual dispenser shown in FIG. 2;
FIG. 10 is a left-end elevational view of the individual dispenser shown in FIG. 2;
FIG. 1 1 is a right-end elevational view of the individual dispenser shown in FIG. 2;
FIG. 12 is a cross-sectional view taken through FIG. 9 along the line 1212 in the unactuated condition;
FIG. 13 is a cross-sectional view similar to FIG. 12 in the actuated condition;
FIG. 14 is a top plan view of a ganged disc dispenser for use in the performance of the method of this invention and which comprises one apparatus aspect of this invention;
FIG. 15 is a front view in elevation of the dispenser shown in FIG. 14;
FIG. 16 is a right-end view of the dispenser shown in FIG. 15;
FIG. 17 is a cross-sectional view taken through FIG. 14 along theline 17--17;
FIG. 18 is a cross-sectional view taken through FIG. 15 along the line 1818;
FIG. 19 is a cross-sectional view taken through FIG. 14 along the line 19-19 with the dispenser in the ready position;
FIG. 20 is a cross-sectional view similar to FIG. 19, but in the dispensing position; and
FIG. 21 is a cross-sectional view taken through FIG. 20 along the line 21-21.
BRIEF DESCRIPTION OF THE PREFERRED EMBODIMENTS In FIGS. 1-7 is shown an antibiotic disc dispenser 11 1 in which a number of individual self-containeddispensers l 15 are mounted onbase fixture 116. Dispensers are accordingly mounted insockets 118 disposed intablemechanism 119.Sockets 118 are comprised of substantiallyrectangular slots 120 intop plate 122 and tailedcircular holes 125 inbottom plate 123 ofdispensing table mechanism 119.
Individual dispenser 115 shown in FIGS. 9-13 includes chuted body within whichslide carriage 130 moves against the force ofcompression spring 162 and upon whichcover 164 is mounted onhorn 166.Cartridge tube 39 is inserted betweeninternal contact ridges 169 inclamp 170 on the front ofcover 164 and containsweight 172 pushing down onfeed clip 174 which rests on the stack ofantibiotic discs 16 to be discharged bydispenser 115 as later described.
Details of self-containeddispensers 115 are shown in FIGS. 9-1'3.Dispenser 115 is shown in an unactuated condition in FIGS. 9-12 with the return movement ofslide carriage 130 arrested bytail plate 192 ofcover 164. The aperturedend 194 ofslide plate 195 remote frompin 128 is thinner than therear end 196 to disposedisc feeding aperture 198 in a thinner shoulderedportion 194 ofslide plate 195. This facilitates smooth operation ofslide carriage 130 and dependable feeding ofdiscs 16. The thickerrear portion 196 ofslide plate 195 smoothlyconfines discs 16 withintubular cartridge 39 which is inserted within shoulderedsocketed funnel 200 inbody 160.
Weight 172 intube 39 has abottom stern 202 disposed against the bottom of angularU-shaped clip 174 to urge it downwardly.Weight 172 weighs, for example, 4 grams andclip 174 which is for example made of spring material such as beryllium copper, causes about 2 grams of frictional resistance in rubbing against the inner walls oftubes 39, to leave a resultant 2 grams of force pushing down on the stack ofdiscs 16. Points 204 ofclip 174 ratchet the downward movement ofclip 174 and maintain the stack ofdiscs 16 firmly packet together. The disposition ofstem 202 ofweight 172 on the bottom arm 206 ofclip 174 clear ofside arms 208, preventsweight 172 from bendingclip 174 and interfering with the efficient operation ofclip 174.Dimple 210 at the center of bottom end 206 ofclip 174 is higher thanslot 212 inbody 160 through which slide 130 passes to preventclip 174 from dropping intoaperture 198 and binding operation ofslide 130.
FIGS. 12 and 13 show the engagement ofsocket 214 withincover 164 overhorn 166 onbody 160.Clearing hole 216 in therear actuating end 217 ofslide carriage 130 passes over taperedguide shaft 218 onbody 160 about whichcompression spring 162 is mounted. The rearward movement ofslide carriage 130 is arrested bytail plate 192 extending downwardly fromcover 164. Forward movement ofslide 130 from the position shown in FIG. 12 to that shown in FIG. 13 carries adisc 16 from the stack incartridge 39 over the openupper end 127 ofchute 126 through which it is dropped.Dispenser 1 15 is shown being manually actuated byfingers 222 in FIG. 13, which is the manner in which dispensers 115 are individually used.Dispensers 115 are also capable of simultaneous multiple operation when mounted on a supporting and actuating fixture as otherwise described herein.Semicircular portion 129 of the upper rim ofopen end 127 ofchute 126 is chamfered to help direct dischargeddiscs 16 intochute 126.
The installation ofindividual disc dispensers 115 is illustrated in FIGS. l-4, showingchutes 126 disposed abovecuvette 12 and its correspondingupper ports 26 through whichdiscs 16 are discharged intotubular disc holder 29 of cuvette compartments S -S Cuvette 12 is a compartmented container for inoculated broth used for measuring the effect of antimicrobial agents on the growth of microorganisms in the broth. The detection of growth in broth by forward light scattering requires such a chamber to be both optically transparent to the irradiating light used and geometrically consistent with the light scattering photometer. Convenient and rapid examination of the efi'ect of many antimicrobial agents on the growth of a given microorganism is accomplished by a linear array of such optical chambers as a single unit, described in aforementioned copending application Ser. No. 281,946, filed Aug. I8, 1971. Cuvette l2 permits the convenient introduction of an equal volume of broth inoculum into eachchamber S. Cuvette 12 also has the capability of conveniently accepting an antimicrobial impregnated paper disc into all test chambers and is not capable of accepting such an antimicrobial disc in its-single control chamber. Furthermore,cuvette 12 is water-tight, optically polished, optically reproducible, inexpensive, relatively small, stackable, and may be disposable.Cuvette 12 is a linear array of one control chamber, S and 12 antimicrobial test chambers, 8 -12.
A row oflobes 15 extends the entire length of the long axis of the cuvette (excluding the reservoir). They are connected to the reservoir by amajor distribution port 31, and accept broth inoculum from the reservoir by manually rotating the cuvette to lower them and cause equal amounts of solution to fill them through distributingports 33 assisted by return flow of air through vents 35. The area ofports 33 increases away from reservoir R.
Thirteen disconnectedlight scattering lobes 17 of chambers S (S S S accept an equal volume of broth inoculum from interconnected distributinglobes 15 by manually rotating the cuvette about its long axis to lower them. Once filled with broth inoculum the thirteen chambers S are isolated from each other by thepartitioning walls 36. Distributingports 33 and air distribution vents 35, located at the top of eachpartition 36 and well above the broth level are the only interconnections between the chambers. These vents are necessary for proper fluid distribution into lowered distributinglobes 15 as described above.
Twelve aperturedtubular fingers 29 extend down into the 12 test scattering chambers (S S S Each hollow finger, known as a disc holder, accepts an antimicrobial paper disc 16 (6.5 mm diameter) via 12disc ports 26 on the top surface ofcuvette 12. The disc drops into thedisc holder 29 and comes to rest on thefloor 73 of this holder. Two elution ports, E, in the walls of the disc holder adjacent to the disc permit elution of antimicrobial agent into the surrounding broth innoculum of the scattering chamber. As shown in FIG. 16 (for reference only) a strip 34 of flexible sealing material with twelve nipples 40 (called the closure inserts) are inserted into thedisc ports 26 to provide a watertight seal for each disc holder. Strip 34 is received between parallel rails34a straddling ports 26 on the upper surface ofcuvette 12 and it is usually removed whilecuvette 12 is inserted incavity 50 ofdispenser 14. An L-shaped bracket B located on the back ofcuvette 12 and extending the length of the cuvette long axis enables the attachment of the cuvette to holding brackets in processing analyzing equipment (not shown).
As shown in FIG. 3,cuvette 12 is aligned in its required position .underchutes 126 by insertion oflegs 238 and 240 respectively within left-hand locating shoe 242 and right-hand locating shoe 244 into whichcuvette 12 is inserted by pushing it from front to back intochamber 246 disposed between dispensingtable assembly 119 andlower base platform 248.
As shown inGFIGS. 3 and 4, dispensing table mechanism orassembly 1 19 is comprised of anelongated aluminum extrusion 250 incorporatingtop plate 122 andbottom plate 123.Extrusion 250 also includes pairs of opposedlongitudinal grooves 252 and 254 disposed belowbottom plate 123 which receive slidingcam actuating plate 256 and lockingplate 258, which are further described in FIGS. 5-7.Base platform 248 is primarily comprised of anelongated channel 260 made of stainless steel, internally reinforced byaluminum tubes 262 which secure the lower ends 264 and 266 of C- shaped end supports 268 together by threaded engagement bycap screws 270. The upper ends 272 and 274 of end supports 268 are secured toextrusion 250 bycap screws 276. End supports 268 are identical to each other, but the left-hand and right-hand installations are inverted l80 with respect to each other. This disposeschannel 278 receivingoperating plunger 280 at the top of right-hand end support 268, andchannel 278 is inoperatively disposed at the bottom 264 of left-hand end support 268. The outer open ends of end supports 268 are covered byend sheets 281 which are removably held in place bylugs 282 which are wedged against U- shapedclips 284 secured by thecap screws 270 and 276 to thecentral securing wall 286 of end supports 268.Lugs 282 are also wedged between a slight space not shown between the sides ofU-shaped clips 284 and the adjacent wall ofend support 268.
FIG. 5 shows alocking plate 258 in the unlocked position for receivingchutes 126 ofindividual disc dispensers 115. Lockingplate 258, is for example, a thin framed rectangular plate formed of a relatively strong sheet material, such as polycarbonate resin. The use of a polycarbonate resin in the grooves of an aluminum extrusion provides a degree of self-lubrication. L- shaped locking lugs 288 project within lockingplate 258 and havetips 290, which engage over locking lugs 124 onchutes 126.Wedges 292 shown in FIG. 3 are incorporated under lockingtips 290 for securely engaging overlugs 124 onchutes 126 to holdindividual disc dispensers 115 securely in place.
Lockingplate 258 is moved back and forth from the unlocked to locked positions by upwardly extendingpeg 294, which is for example cast as an integral part of lockingplate 258.Peg 294 extends upwardly througharcuate slot 296 intop plate 122 which it maintainspeg 294 and lockingplate 258 in its extremities in conjunction with the resiliency ofpeg 294.
Cam actuating plate 256 is a thin framed rectangular sheet made of polycarbonate plastic, similarly tosheet 258, and it includes sloped orinclined cam surface 298 of rounded saw tooth or triangular form extending inwardly within itscentral opening 300. Camactuating plate is urged to the left extremity of travel in the nondispensing position shown in FIG. 5 bycoil springs 302 secured to endsupports 268 overlugs 304. Dispensing actuation ofcam plate 256 to the right is accomplished by pushingplunger 280 downwardly, as shown byarrow 306 in FIG. 3, which pullscam plate 256 to the right throughflexible strap 308 connecting the righthand side ofcam plate 256 to thebottom 310 ofplunger 280.Flexible cable 308 is of a strip of a strong flexible material, such as nylon-coated stainless steel cable or other suitable flexible material.
The operation of dispenser 111 is easily accomplished afterindividual dispensers 115 are installed, as shown in FIGS. 5-7. Main dispenser 111 is unlocked for receivingindividual dispensers 115. FIG. 6 shows the position of lockingplate 258 in the left-hand or locking position in which peg 294 is in the left hand side ofarcuate slot 296 and lockinglugs 288 are moved in line withchutes 126 of dispenser and in engagement over locking lugs 124 onchutes 126.
The dispensing position of dispenser 111 is shown in FIG. 7 in whichcam plate 256 is moved to the right by downward pressure ofplunger 280 to pull connectingcable 308 to the right in the direction ofarrow 312. Movement ofcam plate 256 to the right forces sawtoothed cam elements 298 against dispenser-operatingpins 128 to force them inwardly within framedopening 300 to operateindividual dispensers 115 in the manner previously described. Visual observation and verification that discs have been discharged from each ofdispensers 115 and intoports 26 ofcuvette 12 is afforded by the open tops 127 ofchutes 126 which are exposed at the top ofdispenser table assembly 119 on the upper portion of dispenser 111. Any jams which might occur, can also be easily cleared through exposedtops 127 of dispensingchutes 126. FIG. 1 also has aLOCK direction indicia 314 andindividual dispenser numbers 316 to facilitate locking and unlocking and coordination of the type of discs in each individual dispenser.
Dispensers 115 may be easily reloaded by removingcartridge tubes 39 and replacing them in the manner previously described. Only two individual dispensers are shown in solid outline installed in main dispenser 111 in FIGS. 1-4. One additionalindividual dispenser 115 is shown in FIGS. 1-3 to indicate the manner in which the full complement ofindividual dispensers 1 15 is installed.
Disc dispenser 14 shown in FIGS. 14-21 conveniently and .rapidly introduces a single antimicrobial impregnatedpaper disc 16 into each of the l2 (or less if desired)disc holders 29 ofcuvette 12 with the entire panel of discs added simultaneously by a simple manual manipulationfTheupper plate section 38 of thefreestanding dispenser 14 accepts a maximum of 12cartridges 39 containingantimicrobial discs 16.Glass cartridges 39 are identical to those currently being used for Kirby-Bauer discs. Thelower plate section 41 ofdispenser 14 contains atrack guide 48 which accepts acuvette 12 in .upright position.Upper plate 38 andlower plate 41 are joined in a channel form by rearvertical wall 43.Cuvette 12 is inserted ontrack 48 intocavity 50 untilstop 45 is reached. The top ofcuvette 12 is guided by insertion of the parallel rails 34a in slot 27a in the bottom ofplate 27 later described. Another slot 27b is provided in the bottom ofplate 27 for passage ofinoculum tube 78. Themiddle section 47 of thedispenser 14 has mechanism 49 somewhat similar to that shown in US. Pat. Nos. 3,031,819, 3,036,703 and 3,115,992, whichupon actuation of alever 51, slides asingle disc 16 out of eachcartridge 39 and drops thedisc 16 into thetubular disc holder 29 of the cuvette. In this manner, 12 discs can be simultaneously added to a cuvette.
Cartridge tubes 39 are inserted throughholes 19 inupper plate 38 andadjacent support plate 21 andspacer plate 23.Midsection 47 includes spacedhorizontal guide plates 25 and 27 between which slideplate 37 reciprocates.Upper plate 25 includes counterboredholes 52 which receive the bottom ends ofcartridge 39.Slide plate 37 includesholes 53 which receivediscs 16 fromtubes 39 and drop them throughholes 55 inplate 27 intoports 26 incuvette 12.Viewing slot 21a allows the user to monitor operation and to easily clear jamming through holes 530 inplate 25 caused by any malfunctions, such as jamming of adisc 16 in ahole 55 inplate 27.Plate 37 is reciprocated bylever 51 throughsplined shaft 57.Racks 59 energizingsplined shaft 57 are connected to the ends ofslide plate 37 to move it back and forth bylever 51. Compression springs 61 react betweenvertical wall 43 and the rear edge ofslide plate 37 to return it to the receiving position.
I claim:
1. A disc dispenser for dispensing discs from cartridges to a compartmented container having an array of compartments having top openings for insertion of said discs, said dispenser comprising a base fixture, a dispensing table mechanism mounted upon said base fixture, said dispensing table mechanism having an array of upper and lower holes offset a predetermined distance from each other, cartridge-supporting means disposed on said dispensing table mechanism for holding said cartridges above said upper holes for successively dispensing discs into them, an apertured dispensing plate means mounted in said dispensing table mechanism for sliding movement from alignment with said upper holes to alignment with said lower holes, drive means connected to said dispensing table mechanism for moving said dispensing plate means from one said alignment to the other whereby discs received from said upper holes are carried and dropped into said lower holes, a compartmented container-receiving chamber disposed under said dispensing table mechanism and within said base fixture for holding said compartmented container with its apertures aligned with said lower holes to cause said discs dispensed through said lower holes to drop into said compartments in said container, and auxiliary apertures in said dispensing table mechanism subatantially aligned with said lower holes to permit visual verification of dispensed discs and to facilitate clearing discs which may jam in said lower holes.
2. A disc dispenser as set forth inclaim 1 wherein said dispensing table mechanism comprises a pair of upper and lower spaced parallel apertured plates, said array of upper holes being disposed in said upper apertured plate and said lower holes being disposed in said lower apertured plate, said dispensing table mechanism also comprising an apertured dispensing plate mounted inbetween said spaced parallel apertured plates for sliding movement from alignment with said upper holes to alignment with said lower holes.
3. A disc dispenser as set forth inclaim 2 wherein said cartridge-supporting means comprises a top apertured plate disposed a short distance above said spaced parallel plates.
4. A disc dispenser as set forth inclaim 3 wherein said auxiliary apertures are provided in said top apertured plate.
5. A disc dispenser as set forth inclaim 1 wherein said dispensing table mechanism has a plurality of sockets for receiving individual disc dispensers, an individual disc dispenser being disposable in each of said sockets, each of said individual disc dispensers incorporating said upper and lower holes, a locking means on the dispensing table mechanism for engaging said individual disc dispensers in said sockets and securing them to said dispensing table mechanism said drive means being connected with said individual disc dispensers whereby said disc dispensers are simultaneously operated to dispense discs from each of the individual disc dispensers and discharge them into said compartmented container.
6. A disc dispenser as set forth inclaim 5 wherein each of said disc dispensers incorporates a body extending laterally therefrom, and said sockets being constructed and arranged for disposing the bodies of disc dispensers installed in said sockets in alternate directions whereby space is provided therebetween for actuating said dispensers.
7. A disc dispenser as set forth inclaim 5 wherein said dispensing table mechanism incorporates a top apertured receiving plate and a lower base plate for holding the bodies of said dispensers and supporting them.
8. A disc dispenser as set forth inclaim 7 wherein a sliding locking plate having a plurality of locking surfaces is incorporated in said dispensing table mechanism for engaging said individual dispensers and holding them securely in position for dispensing discs.
9. A disc dispenser as set forth in claim 8 wherein each of said individual dispensers has a locking projection extending laterally from it, and said sliding locking plate comprises a locking frame plate member having a plurality of locking lugs disposed within it for engaging said locking projections on said individual dispensers.
10. A disc dispenser as set forth inclaim 9 wherein said locking frame plate member has a plurality of L- shaped lugs extending inwardly within it.
11. A disc dispenser as set forth inclaim 5 wherein each of said individual disc dispensers has an actuating pin, and said drive means comprises a sliding cam plate having a plurality of cam elements with one of said cam elements operatively engaging each of said actuating pins.
12. A disc dispenser as set forth inclaim 10 wherein said sliding cam plate comprises a substantially rectangular cam frame plate, said cam elements comprise sloped surfaces extending inwardly within said cam frame plate.
13. A disc dispenser as set forth inclaim 12 wherein a framed locking plate having a plurality of locking lugs extending inwardly thereforrn is disposed adjacent said cam frame plate, said framed locking plate having a plurality of L-shaped lugs extending inwardly within it.
14. A disc dispenser as set forth inclaim 5 wherein said drive means comprises a plunger, end supports on said base fixture, a channel in one of said supports for receiving said plunger, and a connecting drive linkage connected between said dispensing table mechanism and said plunger for actuating said dispensing table mechanism.
15. A disc dispenser as set forth inclaim 14 wherein said connecting drive linkage comprises a flexible cable.
16. A disc dispenser as set forth inclaim 5 wherein said compartmented container-receiving chamber comprises a lower base plate spaced below said dispensing table mechanism a sufiicient distance to receive said compartmented container therebetween, and aligning lugs on said base plate for holding said compartmented container in alignment with the holes in the dispensing table mechanism.
17. A ganged antibiotic disc dispenser for supplying antibiotic discs from cartridges to a compartmented container having an array of compartments each having an aperture for insertion of said antibiotic discs, said dispenser comprising a base, a pair of upper and lower parallel spaced apertured plates mounted upon said base, said pair or parallel spaced apertured plates each having an array of holes offset a predetermined distance from each other, an apertured dispensing plate mounted inbetween said spaced plates for sliding movement from alignment with one of said array of holes to alignment with the other, drive means on said base for moving said dispensing plate from one said alignment to the other whereby discs received from said upper spaced plate are carried and dropped into said lower spaced plate, a compartmented container receiving chamber disposed between said base and said lower spaced plate for holding said compartmented container with its apertures aligned with the apertures in said lower spaced plate to cause said disc dispensed through said lower spaced plate to drop into said compartment in said container, cartridge supporting'means disposed on said base above said spaced plates for holding said cartridges above the apertures in said upper spaced plate to successively dispense discs into it, and auxiliary apertures in the said upper spaced plate substantially aligned with said apertures in said lower spaced plate to facilitate clearing discs which may jam in said apertures of said lower spaced plate.
18. A ganged antibiotic disc dispenser as set forth inclaim 17 wherein said cartridge supporting means comprises an upper apertured plate disposed a short distance above said spaced plates.
19. A ganged antibiotic disc dispenser as set forth inclaim 18 wherein said base and said upper apertured plate are comprised of a pair of horizontal plates joined by a substantially vertical wall to comprise a channel, said pair of spaced plates and said drive means being connected to said substantially vertical wall, and an access opening being provided in said channel to provide access to said auxiliary apertures for inspection and clearing.
20. A ganged antibiotic disc dispenser as set forth inclaim 19 wherein upper and lower slotted bars are provided in said receiving space for aligning said apertures in said compartmented container under said spaced parallel spaced plates.
21. A ganged antibiotic disc dispenser as set forth inclaim 17 wherein said drive means comprises a splined shaft engaged with a pair of racks connected to the sides of said apertured dispensing plate.

Claims (21)

1. A disc dispenser for dispensing discs from cartridges to a compartmented container having an array of compartments having top openings for insertion of said discs, said dispenser comprising a base fixture, a dispensing table mechanism mounted upon said base fixture, said dispensing table mechanism having an array of upper and lower holes offset a predetermined distance from each other, cartridge-supporting means disposed on said dispensing table mechanism for holding said cartridges above said upper holes for successively dispensing discs into them, an apertured dispensing plate means mounted in said dispensing table mechanism for sliding movement from alignment with said upper holes to alignment with said lower holes, drive means connected to said dispensing table mechanism for moving said dispensing plate means from one said alignment to the other whereby discs received from said upper holes are carried and dropped into said lower holes, a compartmented container-receiving chamber disposed under said dispensing table mechanism and within said base fixture for holding said compartmented container with its apertures aligned with said lower holes to cause said discs dispensed through said lower holes to drop into said compartments in said container, and auxiliary apertures in said dispensing table mechanism subatantially aligned with said lower holes to permit visual verification of dispensed discs and to facilitate clearing discs which may jam in said lower holes.
17. A ganged antibiotic disc dispenser for supplying antibiotic discs from cartridges to a compartmented container having an array of compartments each having an aperture for insertion of said antibiotic discs, said dispenser comprising a base, a pair of upper and lower parallel spaced apertured plates mounted upon said base, said pair or parallel spaced apertured plates each having an array of holes offset a predetermined distance from each other, an apertured dispensing plate mounted inbetween said spaced plates for sliding movement from alignment with one of said array of holes to alignment with the other, drive means on said base for moving said dispensing plate from one said alignment to the other whereby discs received from said upper spaced plate are carried and dropped into said lower spaced plate, a compartmented container receiving chamber disposed between said base and said lower spaced plate for holding said compartmented container with its apertures aligned with the apertures in said lower spaced plate to cause said disc dispensed through said lower spaced plate to drop into said compartment in said container, cartridge supporting means disposed on said base above said spaced plates for holding said cartridges above the apertures in said upper spaced plate to successively dispense discs into it, and auxiliary apertures in the said upper spaced plate substantially aligned with said apertures in said lower spaced plate to facilitate clearing discs which may jam in said apertures of said lower spaced plate.
US496287A1972-08-181974-08-09Disc dispenserExpired - LifetimeUS3899011A (en)

Priority Applications (18)

Application NumberPriority DateFiling DateTitle
US496287AUS3899011A (en)1972-08-181974-08-09Disc dispenser
CA220,109ACA1008029A (en)1974-08-091975-02-14Multiple disc dispenser
GB6868/75AGB1496015A (en)1974-08-091975-02-18Multiple disc dispenser
IL46660AIL46660A (en)1974-08-091975-02-18Disc dispenser
SE7502000ASE412890B (en)1974-08-091975-02-21 DEVICE FOR EXHAUSTING A MULTIPLE DISC
AU78495/75AAU491178B2 (en)1974-08-091975-02-24Multiple disc dispenser
AR257731AAR211094A1 (en)1974-08-091975-02-24 A DEVICE FOR A PLURALITY OF DISCS.
FI750533AFI58306C (en)1974-08-091975-02-25 EXTENSION OF FLOWER
NL7502269ANL7502269A (en)1974-08-091975-02-26 MULTIPLE DISPENSER FOR DISCS.
DE2508820ADE2508820C2 (en)1974-08-091975-02-26 Device for the simultaneous dispensing of a number of slices containing active substance
DK80275AADK139928B (en)1974-08-091975-02-28 Apparatus for dispensing a number of antibiotic slices.
BE1006487ABE826106A (en)1974-08-091975-02-28 MULTIPLE ANTIBIOTIC DISC DISPENSER
FR7506349AFR2281297A1 (en)1974-08-091975-02-28 MULTIPLE ANTIBIOTIC DISC DISPENSER
CH257675ACH590926A5 (en)1974-08-091975-02-28
IT48387/75AIT1029895B (en)1974-08-091975-02-28 MULTIPLE DISC DISTRIBUTOR FROM TUBULAR CARTRIDGES WHERE THEY ARE STACKED IN A COMPARTMENT CONTAINER
ES435228AES435228A1 (en)1974-08-091975-03-01 A SUPPLY DEVICE FOR A PLURALITY OF DISCS.
JP50025862AJPS5756349B2 (en)1974-08-091975-03-03
BR1230/75ABR7501230A (en)1974-08-091975-03-03 MULTIPLE DISK DISTRIBUTOR TO SUPPLY CARTRIDGE DISCS INTO A COMPARTMENTED CONTAINER

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
US00281946AUS3832532A (en)1972-08-181972-08-18Method and apparatus for testing antibiotic susceptibility
US496287AUS3899011A (en)1972-08-181974-08-09Disc dispenser

Publications (1)

Publication NumberPublication Date
US3899011Atrue US3899011A (en)1975-08-12

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US496287AExpired - LifetimeUS3899011A (en)1972-08-181974-08-09Disc dispenser

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Cited By (20)

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US4213825A (en)*1976-08-231980-07-22Rolf SaxholmApparatus for testing reactions
US4236211A (en)*1978-09-151980-11-25Pfizer Inc.Method and apparatus for determining the minimum concentration of antibiotic necessary to at least inhibit microorganism growth
US4288543A (en)*1977-01-281981-09-08Pfizer Inc.Method and apparatus for identifying microorganisms
US20020098518A1 (en)*2000-01-072002-07-25Douglas LevinsonRapid identification of conditions, compounds, or compositions that inhibit, prevent, induce, modify, or reverse transitions of physical state
US20020177167A1 (en)*2000-01-072002-11-28Levinson Douglas A.Method and system for planning, performing, and assessing high-throughput screening of multicomponent chemical compositions and solid forms of compounds
US20020183938A1 (en)*2000-04-072002-12-05Kobylecki Ryszard JurekInvestigating different physical and/or chemical forms of materials
US20030059837A1 (en)*2000-01-072003-03-27Levinson Douglas A.Method and system for planning, performing, and assessing high-throughput screening of multicomponent chemical compositions and solid forms of compounds
US20030106492A1 (en)*2001-09-072003-06-12Douglas LevinsonApparatus and method for high-throughput preparation, visualization and screening of compositions
US20030138940A1 (en)*2000-01-072003-07-24Lemmo Anthony V.Apparatus and method for high-throughput preparation and characterization of compositions
US20030162226A1 (en)*2000-01-072003-08-28Cima Michael J.High-throughput formation, identification, and analysis of diverse solid-forms
US20050130220A1 (en)*2000-01-072005-06-16Transform Pharmaceuticals, Inc.Apparatus and method for high-throughput preparation and spectroscopic classification and characterization of compositions
GB2411894A (en)*2004-03-112005-09-14Mast Group LtdDispensing device
US20060057734A1 (en)*2002-11-042006-03-16Hongming ChenPreformulation analysis and optimization
US20060129329A1 (en)*2001-04-092006-06-15Kobylecki Ryszard JInvestigating different physical and/or chemical forms of materials
US20070021929A1 (en)*2000-01-072007-01-25Transform Pharmaceuticals, Inc.Computing methods for control of high-throughput experimental processing, digital analysis, and re-arraying comparative samples in computer-designed arrays
US20070020662A1 (en)*2000-01-072007-01-25Transform Pharmaceuticals, Inc.Computerized control of high-throughput experimental processing and digital analysis of comparative samples for a compound of interest
WO2009073603A1 (en)*2007-11-292009-06-11Nu-Life Rpoducts, Inc.Single stack wafer dispenser
US20110284568A1 (en)*2008-11-262011-11-24Bayer Schering Pharma AktiengesellschaftCartridge, a pharmaceutical dispenser containing the cartridge, and applications of said cartridge and said pharmaceutical dispenser
US8996163B2 (en)2011-04-292015-03-31Bd Kiestra B.V.Disc dispensing device, tubular container for use in such a disc dispensing device and method of dispensing discs
WO2022095043A1 (en)*2020-11-092022-05-12沈凌云Gene detection kit

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US3300087A (en)*1965-05-041967-01-24Difco Lab IncArticle dispensing magazine and a dispenser with removable magazines
US3304965A (en)*1964-02-051967-02-21Pfizer & Co CDevice for collecting separate quantities of liquid
US3372717A (en)*1966-01-261968-03-12Friden IncChad collection apparatus

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US3304965A (en)*1964-02-051967-02-21Pfizer & Co CDevice for collecting separate quantities of liquid
US3300087A (en)*1965-05-041967-01-24Difco Lab IncArticle dispensing magazine and a dispenser with removable magazines
US3372717A (en)*1966-01-261968-03-12Friden IncChad collection apparatus

Cited By (34)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US4213825A (en)*1976-08-231980-07-22Rolf SaxholmApparatus for testing reactions
US4288543A (en)*1977-01-281981-09-08Pfizer Inc.Method and apparatus for identifying microorganisms
US4236211A (en)*1978-09-151980-11-25Pfizer Inc.Method and apparatus for determining the minimum concentration of antibiotic necessary to at least inhibit microorganism growth
US20070020662A1 (en)*2000-01-072007-01-25Transform Pharmaceuticals, Inc.Computerized control of high-throughput experimental processing and digital analysis of comparative samples for a compound of interest
US20050118636A9 (en)*2000-01-072005-06-02Douglas LevinsonRapid identification of conditions, compounds, or compositions that inhibit, prevent, induce, modify, or reverse transitions of physical state
US7108970B2 (en)2000-01-072006-09-19Transform Pharmaceuticals, Inc.Rapid identification of conditions, compounds, or compositions that inhibit, prevent, induce, modify, or reverse transitions of physical state
US20030059837A1 (en)*2000-01-072003-03-27Levinson Douglas A.Method and system for planning, performing, and assessing high-throughput screening of multicomponent chemical compositions and solid forms of compounds
US7061605B2 (en)2000-01-072006-06-13Transform Pharmaceuticals, Inc.Apparatus and method for high-throughput preparation and spectroscopic classification and characterization of compositions
US20030138940A1 (en)*2000-01-072003-07-24Lemmo Anthony V.Apparatus and method for high-throughput preparation and characterization of compositions
US20030162226A1 (en)*2000-01-072003-08-28Cima Michael J.High-throughput formation, identification, and analysis of diverse solid-forms
US20050089923A9 (en)*2000-01-072005-04-28Levinson Douglas A.Method and system for planning, performing, and assessing high-throughput screening of multicomponent chemical compositions and solid forms of compounds
US20050095696A9 (en)*2000-01-072005-05-05Lemmo Anthony V.Apparatus and method for high-throughput preparation and characterization of compositions
US20070021929A1 (en)*2000-01-072007-01-25Transform Pharmaceuticals, Inc.Computing methods for control of high-throughput experimental processing, digital analysis, and re-arraying comparative samples in computer-designed arrays
US20050118637A9 (en)*2000-01-072005-06-02Levinson Douglas A.Method and system for planning, performing, and assessing high-throughput screening of multicomponent chemical compositions and solid forms of compounds
US20050130220A1 (en)*2000-01-072005-06-16Transform Pharmaceuticals, Inc.Apparatus and method for high-throughput preparation and spectroscopic classification and characterization of compositions
US20050191614A1 (en)*2000-01-072005-09-01Millenium Pharmaceuticals, Inc.High-throughput formation, identification and analysis of diverse solid forms
US20020098518A1 (en)*2000-01-072002-07-25Douglas LevinsonRapid identification of conditions, compounds, or compositions that inhibit, prevent, induce, modify, or reverse transitions of physical state
US20020177167A1 (en)*2000-01-072002-11-28Levinson Douglas A.Method and system for planning, performing, and assessing high-throughput screening of multicomponent chemical compositions and solid forms of compounds
US6965832B2 (en)2000-04-072005-11-15Millennium Pharmaceuticals, Inc.Investigating different physical and/or chemical forms of materials
US20060025934A1 (en)*2000-04-072006-02-02Kobylecki Ryszard JInvestigating different physical and/or chemical forms of materials
US20020183938A1 (en)*2000-04-072002-12-05Kobylecki Ryszard JurekInvestigating different physical and/or chemical forms of materials
US20060129329A1 (en)*2001-04-092006-06-15Kobylecki Ryszard JInvestigating different physical and/or chemical forms of materials
US20030106492A1 (en)*2001-09-072003-06-12Douglas LevinsonApparatus and method for high-throughput preparation, visualization and screening of compositions
US20060057734A1 (en)*2002-11-042006-03-16Hongming ChenPreformulation analysis and optimization
US20100210027A9 (en)*2002-11-042010-08-19Hongming ChenMethod for determining effect of preformulation forms on their dissolution rates
GB2411894A (en)*2004-03-112005-09-14Mast Group LtdDispensing device
GB2411894B (en)*2004-03-112007-09-26Mast Group LtdDispensing device
WO2009073603A1 (en)*2007-11-292009-06-11Nu-Life Rpoducts, Inc.Single stack wafer dispenser
US20110204080A1 (en)*2007-11-292011-08-25Nu-Life Products, Inc.Single Stack Wafer Dispenser
US20110284568A1 (en)*2008-11-262011-11-24Bayer Schering Pharma AktiengesellschaftCartridge, a pharmaceutical dispenser containing the cartridge, and applications of said cartridge and said pharmaceutical dispenser
US9248949B2 (en)*2008-11-262016-02-02Bayer Intellectual Property GmbhCartridge, a pharmaceutical dispenser containing the cartridge, and applications of said cartridge and said pharmaceutical dispenser
US8996163B2 (en)2011-04-292015-03-31Bd Kiestra B.V.Disc dispensing device, tubular container for use in such a disc dispensing device and method of dispensing discs
US9557343B2 (en)2011-04-292017-01-31Bd Kiestra B.V.Disc dispensing device, tubular container for use in such a disc dispensing device and method of dispensing discs
WO2022095043A1 (en)*2020-11-092022-05-12沈凌云Gene detection kit

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