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US3675846A - Continuous flow centrifuge head construction - Google Patents

Continuous flow centrifuge head construction
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US3675846A
US3675846AUS46255AUS3675846DAUS3675846AUS 3675846 AUS3675846 AUS 3675846AUS 46255 AUS46255 AUS 46255AUS 3675846D AUS3675846D AUS 3675846DAUS 3675846 AUS3675846 AUS 3675846A
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chamber
particular axis
head
conduit
liquid
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US46255A
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Kenneth Gus Drucker
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BIO CONSULTANTS Inc
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BIO CONSULTANTS Inc
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Abstract

An improved centrifuge head is provided which is constructed to permit continuous flow of a liquid through the head, whereby sediment and other constituents of the liquid may be removed by the centrifugal forces within the head as the liquid passes therethrough.

Description

United States Patent Drucker 51 July 11,1972
[54] CONTINUOUS FLOW CENTRIFUGE HEAD CONSTRUCTION Kenneth Gus Drucker, Astoria, Oreg.
[52] US. Cl ..233/26 [51] Int. Cl ..B04b 9/12 [58] Field of Search ..233/1E, 26, l A, 27, 46, 47 R, 233/47 A, 21, 22; 285/134, 190; 210/78, 335
[56] References Cited UNITED STATES PATENTS 921,771 5/1909 Whitlock' ..285/134 X 3,443,747 5/1969 Jacobson et al. ..233/22 3,104,225 9/1963 Benedetto ....233/l E 2,587,206 2/1952 Pattinson ..233/46 X 1,479,656 l/l924 Fetterley ...285/134 464,706 12/1891 Burns ..285/l34 Primary Examiner.lordan Franklin Assistant ExaminerGeorge H. Krizmanich Attorney-Jessup & Beecher [57] ABSTRACT An improved centrifuge head is provided which is constructed to permit continuous flow of a liquid through the head, whereby sediment and other constituents of the liquid may be removed by the centrifugal forces within the head as the liquid passes therethrough.
3 Claims, 3 Drawing Figures CONTINUOUS FLOW CENTRIFUGE HEAD CONSTRUCTION BACKGROUND OF THE INVENTION It is usual in most prior art centrifuges to support a plurality of test tubes, or other receptacles, for example, on a rotating head. This permits the various constituents of the liquid samples contained in the test tubes to be separated out by centrifugal forces. Such prior artcentrifuges are well suited, for example, for separating out the various constituents of a multiplicity of difierent liquid samples. For example, when such prior art centrifuges are used for medical purposes, the various receptacles may contain difierent whole blood samples, and the centrifuge action may be used to separate out the red blood cells of each sample so as to determine anaemic conditions.
However, it is often desirable to remove sediment, or other constituents, from a stream of liquid on a continuous basis,
and to provide a continuous stream of the liquid which is free from such constituents. This is achieved by means of the apparatus of the present invention, by passing the liquid through the centrifuge head to be described. The centrifuge head, as will be described in detail herein, is constructed, so that the liquid stream may readily be passed through the head and be subjected to the centrifugal forces within the head on a continuous basis.
The head of the present invention is constructed in a simple and economical manner to include a rotatable housing which defines an inner toroidal-shaped chamber, and a central section which is rotatably mounted on the housing so that it may be held stationary as the housing rotates. An inlet conduit for the fluid stream extends through the central section and into the center of the inner chamber. As the liquid enters the inner chamber, it is subjected to a rotating action, so that the heavier particles of the constituents to be removed are forced out towards the peripheral wall of the chamber. An outlet conduit is provided having an entrance displaced by a predetermined amount from the center of the chamber, and the outlet conduit discharges the fluid from the chamber, but free of the heavier constituents thereof which are forced to the peripheral wall of the chamber and away from the entrance of the latter conduit. A plastic bag may be suspended in the chamber to receive the fluid and to serve as a receptacle for the sediment, so as to obviate the need to clean the inside walls of the chamber.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a side elevation of a centrifuge assembly which incorporates a head constructed in accordance with the concepts of the present invention;
FIG. 2 is a top plan view of the head of FIG. 1, taken essentially along the lines 22 of FIGURE 1; and
FIG. 3 is a side section of the head, taken along the lines 3- 3 of FIG. 2.
DETAILED DESCRIPTION OF THE ILLUSTRATED EMBODIMENTS As shown in FIG. 1, for example, the head of the present invention may include a housing having a generally cylindrical shape. Thehousing 10 is mounted, for example, on thedrive shaft 12 of anelectric motor 14; the drive shaft and motor being supported on a suitable stand orbase 16. When themotor 14 is electrically energized, thedrive shaft 12 is caused to rotate, and thehead 10 is caused to rotate about the axis of rotation of the drive shaft.
The assembly also includes a central hub section which is rotatably mounted in thehead 10, so that thesection 20 may be held stationary as the head rotates. Aninlet conduit 24 extends into thehub section 20 and through the hub section into the interior of thehead 10, as best shown in FIG. 3. Anoutlet conduit 26 also extends through thehub section 20 and like theinlet conduit 24, is coupled to the chamber within the housing.
In the operation of the centrifuge apparatus of FIG. 1, a stream of liquid is introduced into the centrifuge through theinlet conduit 24, and is subject to centrifugal action within thehead 10. A continuous stream of the liquid is discharged from the centrifuge through theconduit 26, the discharge stream being free of the heavier constituents of the inlet stream, which constituents are separated out within thehead 10.
As best shown in FIG. 3, for example, thehead 10 defines an inner chamber which has a generally toroidal configuration, and which is symmetrical about the axis of rotation of the head. Thehub 20 includes a firstupper bracket 51 which is threaded tolower brackets 49 and 53, and which is sealed thereto by an O-ring 57. Thebrackets 51 and 53 are coaxial with the axis of rotation of thehead 10. The resulting assembly, which constitutes thehub 20, is rotatably mounted in thehead 10 bybearings 52.
Aplug 54 is threaded into thehead 10 to hold a central dish-shapedbracket 55 in position in thehead 10. Thebracket 55 is sealed to thehead 10 by means, for example, of an O-ring 56, and it supports thebearings 52. Theinlet conduit 24 extends into thehub 20 through a cap which is threaded to the hub, and which is sealed by means of an O-ring 62. Theinlet conduit 24 is coupled through the cap 60 to a further conduit 66, the conduit 66 extending along the axis of rotation of the head and terminating within the chamber 50 at the center of the chamber. The conduit 66 is sealed by a lip seal 67. Theoutlet conduit 26 is coupled to a further conduit formed by a tubular member 70 which extends through thehub 20 in coaxial relationship with the conduit 66. The conduit 70 is sealed by alip seal 71. The aforesaid conduit is coupled to a radial passage 72 having an entrance displaced from the center of the chamber 50, as shown. An extensible pick-u pipe 73 may be slidably mounted in the passage 72 in telescopic relationship therewith. Thepipe 73 may be extended to any desired length so that selected constituents may be excluded from the discharge stream in the basis of weight. A slinger may be mounted on the conduit 70.
As thehead 10 rotates theconduits 24 and 26, and the associated hub components, are held stationary in thebearings 52. The liquid introduced through theconduit 24 passes through the hub and through the conduit 66 to the center of the chamber 50. The liquid is then subjected to centrifugal forces within the chamber as it rotates with the chamber, and
its heavier constituents move outwardly towards the wall of the chamber. The lighter constituents, however, enter the pick-up pipe 73, and pass through the passageway 72 and up the conduit 74 to be discharged through theconduit 26.
In the manner described above, a continuous stream of liquid may be maintained into and out of the rotatinghead 10, with the stream being continuously subjected to a centrifuge separation action. A plastic bag is suspended around aneck 55a on thecentral bracket 55 so that the ends of the inlet conduit 66 and the pick-up pipe substantially fills the chamber 50. The bag rotates with the chamber and serves as a liner for the chamber and as a receptacle for the sediment removed from the sample. The bag may be supported by cords around its neck and around theneck 55a of the bracket, or by an O-ring in the upper annular groove 55b.
Thelip seals 67 and 71 have been formed to provide an adequate seal for the mechanism and to be more effective than the usual prior art face seals. The O-rings 57 and 62 are also effective since their associated hub components are stationary and there are no centrifugal forces on these seals.
It will be appreciated that although a particular embodiment of the invention has been shown and described, modifications may be made. The following claims are intended to cover the modifications which come within the spirit and scope of the invention.
What is claimed is:
1. A centrifuge head, or the like, which permits a continuous flow of liquid through the centrifuge head and which permits the liquid to be exposed to centrifugal forces as it passes through the centrifuge head so as to separate certain constituents out of the liquid, said centrifuge head including: a housing defining an internal chamber mounted for rotation about a particular axis; a fixed hub section mounted on said housing in coaxial relationship therewith with respect to said particular axis and including a first bracket extending into said chamber and held stationary as the housing rotates about said particular axis; a central dish-shaped bracket rotatably supported on said first bracket within said chamber in axial alignment with said hub section for rotation with said housing about said hub section, a bag supported on said dish-shaped bracket, said dish-shaped bracket having a peripheral shoulder within said chamber coaxial with said particular axis and receiving the neck of the bag to support the bag in the chamber; inlet means including a first conduit extending along said particular axis and through said hub section and through said dish-shaped bracket into said chamber so as to introduce liquid into the center of the chamber; outlet means including a second conduit extending along said particular axis through said dish-shaped bracket and through said hub section coaxially with said first conduit and having an entrance within said chamber displaced radially from the center of said chamber by a predetermined amount; and an extensible pick-up pipe extending horizontally in said chamber and slidably mounted in said second conduit in telescoping relationship therewith and protruding from the entrance thereof.
2. The centrifuge head defined inclaim 1, in which said housing has a configuration such that said chamber is generally toroidal in shape and is symmetrical about said particular axis.
3. The centrifuge head defined inclaim 1, in which said hub section is formed of a plurality of separate brackets threaded to one another and in coaxial relationship with said particular axis.

Claims (3)

1. A centrifuge head, or the like, which permits a continuous flow of liquid through the centrifuge head and which permits the liquid to be exposed to centrifugal forces as it passes through the centrifuge head so as to separate certain constituents out of the liquid, said centrifuge head including: a housing defining an internal chamber mounted for rotation about a particular axis; a fixed hub section mounted on said housing in coaxial relationship therewith with respect to said particular axis and including a first bracket extending into said chamber and held stationary as the housing rotates about said particular axis; a central dishshaped bracket rotatably supported on said first bracket within said chamber in axial alignment with said hub section for rotation with said housing about said hub section, a bag supported on said dish-shaped bracket, said dish-shaped bracket having a peripheral shoulder within said chamber coaxial with said particular axis and receiving the neck of the bag to support the bag in the chamber; inlet means including a first conduit extending along said particular axis and through said hub section and through said dish-shaped bracket into said chamber so as to introduce liquid into the center of the chamber; outlet means including a second conduit extending along said particular axis through said dish-shaped bracket and through said hub section coaxially with said first conduit and having an entrance within said chamber displaced radially from the center of said chamber by a predetermined amount; and an extensible pick-up pipe extending horizontally in said chamber and slidably mounted in said second conduit in telescoping relationship therewith and protruding from the entrance thereof.
US46255A1970-06-151970-06-15Continuous flow centrifuge head constructionExpired - LifetimeUS3675846A (en)

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Cited By (23)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US4350283A (en)*1980-07-011982-09-21Beckman Instruments, Inc.Centrifugal elutriator rotor
US4377253A (en)*1980-02-121983-03-22Syglo International S.A.Coupling assembly particularly for centrifuges
US4397637A (en)*1981-07-131983-08-09The Garrett CorporationApparatus and method for centrifuging
US4636193A (en)*1976-05-141987-01-13Baxter Travenol Laboratories, Inc.Disposable centrifugal blood processing system
EP0211616A3 (en)*1985-08-021988-06-08Sasakura Engineering Co. Ltd.Centrifugal separator for separating sludge in waste water
US4983158A (en)*1986-07-221991-01-08Haemonetics CorporationPlasmapheresis centrifuge bowl
US5733253A (en)*1994-10-131998-03-31Transfusion Technologies CorporationFluid separation system
US20040147865A1 (en)*1994-10-132004-07-29Cianci James P.System and method for processing blood
US20050113237A1 (en)*2003-11-252005-05-26Keith RosielloIntegral seal for centrifuge chamber
US20060240964A1 (en)*2005-04-212006-10-26Fresenius Hemocare Deutschland GmbhMethod and apparatus for separation of particles suspended in a fluid
US20070213191A1 (en)*2006-03-072007-09-13Jacques ChammasRotor defining a fluid separation chamber of varying volume
US8317672B2 (en)2010-11-192012-11-27Kensey Nash CorporationCentrifuge method and apparatus
US8394006B2 (en)2010-11-192013-03-12Kensey Nash CorporationCentrifuge
US8469871B2 (en)2010-11-192013-06-25Kensey Nash CorporationCentrifuge
US8556794B2 (en)2010-11-192013-10-15Kensey Nash CorporationCentrifuge
US8870733B2 (en)2010-11-192014-10-28Kensey Nash CorporationCentrifuge
US9682185B2 (en)2010-11-232017-06-20Haemonetics CorporationApheresis bowl with improved vibration characteristics
US20180195615A1 (en)*2015-09-072018-07-12Mann+Hummel GmbhLiner with Seal for Rotor of Centrifugal Separator
US10125345B2 (en)2014-01-312018-11-13Dsm Ip Assets, B.V.Adipose tissue centrifuge and method of use
RU2733517C2 (en)*2015-07-172020-10-02Стат-Диагностика Энд Инновэйшн, С.Л.Method and apparatus for separating and collecting samples
WO2022035952A1 (en)*2020-08-142022-02-17Fiberlite Centrifuge LlcContinuous bioprocessing centrifuge rotor
US20230160801A1 (en)*2020-04-282023-05-25Horiba, Ltd.Measurement cell and centrifugal sedimentation-type particle-size distribution measuring device using said measurement cell
US12337097B2 (en)2010-11-192025-06-24Dsm Ip Assets B.V.Centrifuge

Citations (6)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US464706A (en)*1891-12-08Crane
US921771A (en)*1908-02-101909-05-18Myron J WhitlockHollow roll.
US1479656A (en)*1920-07-291924-01-01Fetterley RalphCombined mill tee and stuffing box
US2587206A (en)*1950-02-271952-02-26John R PattinsonCentrifugal separator
US3104225A (en)*1960-01-291963-09-17Lourdes Instr CorpContinuous flow centrifuge rotor and liner element
US3443747A (en)*1966-10-141969-05-13Beckman Instruments IncFluid coupling for continuous flow centrifuge

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US464706A (en)*1891-12-08Crane
US921771A (en)*1908-02-101909-05-18Myron J WhitlockHollow roll.
US1479656A (en)*1920-07-291924-01-01Fetterley RalphCombined mill tee and stuffing box
US2587206A (en)*1950-02-271952-02-26John R PattinsonCentrifugal separator
US3104225A (en)*1960-01-291963-09-17Lourdes Instr CorpContinuous flow centrifuge rotor and liner element
US3443747A (en)*1966-10-141969-05-13Beckman Instruments IncFluid coupling for continuous flow centrifuge

Cited By (47)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US4636193A (en)*1976-05-141987-01-13Baxter Travenol Laboratories, Inc.Disposable centrifugal blood processing system
US4377253A (en)*1980-02-121983-03-22Syglo International S.A.Coupling assembly particularly for centrifuges
US4350283A (en)*1980-07-011982-09-21Beckman Instruments, Inc.Centrifugal elutriator rotor
US4397637A (en)*1981-07-131983-08-09The Garrett CorporationApparatus and method for centrifuging
EP0211616A3 (en)*1985-08-021988-06-08Sasakura Engineering Co. Ltd.Centrifugal separator for separating sludge in waste water
US4983158A (en)*1986-07-221991-01-08Haemonetics CorporationPlasmapheresis centrifuge bowl
US20040147865A1 (en)*1994-10-132004-07-29Cianci James P.System and method for processing blood
US20030125182A1 (en)*1994-10-132003-07-03Headley Thomas D.Rotor with elastic diaphragm for liquid-separation system
US5733253A (en)*1994-10-131998-03-31Transfusion Technologies CorporationFluid separation system
US7332125B2 (en)1994-10-132008-02-19Haemonetics CorporationSystem and method for processing blood
US7452322B2 (en)1994-10-132008-11-18Haemonetics CorporationRotor with elastic diaphragm for liquid-separation system
US20050113237A1 (en)*2003-11-252005-05-26Keith RosielloIntegral seal for centrifuge chamber
US20060240964A1 (en)*2005-04-212006-10-26Fresenius Hemocare Deutschland GmbhMethod and apparatus for separation of particles suspended in a fluid
US7473216B2 (en)*2005-04-212009-01-06Fresenius Hemocare Deutschland GmbhApparatus for separation of a fluid with a separation channel having a mixer component
US20070213191A1 (en)*2006-03-072007-09-13Jacques ChammasRotor defining a fluid separation chamber of varying volume
US7998052B2 (en)*2006-03-072011-08-16Jacques ChammasRotor defining a fluid separation chamber of varying volume
US20110237418A1 (en)*2006-03-072011-09-29Jacques ChammasRotor defining a fluid separation chamber of varying volume
US8562501B2 (en)2010-11-192013-10-22Kensey Nash CorporationMethods for separating constituents of biologic liquid mixtures
US8870733B2 (en)2010-11-192014-10-28Kensey Nash CorporationCentrifuge
US8469871B2 (en)2010-11-192013-06-25Kensey Nash CorporationCentrifuge
US8485958B2 (en)2010-11-192013-07-16Kensey Nash CorporationSystems and methods for separating constituents of biologic liquid mixtures
US8556794B2 (en)2010-11-192013-10-15Kensey Nash CorporationCentrifuge
US8317672B2 (en)2010-11-192012-11-27Kensey Nash CorporationCentrifuge method and apparatus
US8617042B2 (en)2010-11-192013-12-31Kensey Nash CorporationMethods for separating constituents of biologic liquid mixtures
US8747291B2 (en)2010-11-192014-06-10Kensey Nash CorporationMethods for separating constituents of biologic liquid mixtures
US8758211B2 (en)2010-11-192014-06-24Kensey Nash CorporationCentrifuge
US11167292B2 (en)2010-11-192021-11-09Dsm Ip Assets B.V.Centrifuge
US8974362B2 (en)2010-11-192015-03-10Kensey Nash CorporationCentrifuge
US9114408B2 (en)2010-11-192015-08-25Kensey Nash CorporationCentrifuge
US10646884B2 (en)2010-11-192020-05-12Dsm Ip Assets B.V.Centrifuge
US9987638B2 (en)2010-11-192018-06-05Dsm Ip Assets, B.V.Centrifuge
US12337097B2 (en)2010-11-192025-06-24Dsm Ip Assets B.V.Centrifuge
US8394006B2 (en)2010-11-192013-03-12Kensey Nash CorporationCentrifuge
US10155083B2 (en)2010-11-232018-12-18Haemonetics CorporationApheresis bowl with improved vibration characteristics
US9682185B2 (en)2010-11-232017-06-20Haemonetics CorporationApheresis bowl with improved vibration characteristics
US10125345B2 (en)2014-01-312018-11-13Dsm Ip Assets, B.V.Adipose tissue centrifuge and method of use
US10711239B2 (en)2014-01-312020-07-14Dsm Ip Assets B.V.Adipose tissue centrifuge and method of use
US11549094B2 (en)2014-01-312023-01-10Dsm Ip Assets B.V.Adipose tissue centrifuge and method of use
US12018244B2 (en)2014-01-312024-06-25Dsm Ip Assets B.V.Adipose tissue centrifuge and method of use
RU2733517C2 (en)*2015-07-172020-10-02Стат-Диагностика Энд Инновэйшн, С.Л.Method and apparatus for separating and collecting samples
US10919040B2 (en)2015-07-172021-02-16Stat-Diagnostica & Innovation, S.L.Method for sample separation and collection
US20180195615A1 (en)*2015-09-072018-07-12Mann+Hummel GmbhLiner with Seal for Rotor of Centrifugal Separator
US20230160801A1 (en)*2020-04-282023-05-25Horiba, Ltd.Measurement cell and centrifugal sedimentation-type particle-size distribution measuring device using said measurement cell
US12313645B2 (en)*2020-04-282025-05-27Horiba, Ltd.Measurement cell and centrifugal sedimentation-type particle-size distribution measuring device using said measurement cell
WO2022035952A1 (en)*2020-08-142022-02-17Fiberlite Centrifuge LlcContinuous bioprocessing centrifuge rotor
CN116157205A (en)*2020-08-142023-05-23费柏莱特离心机有限公司Centrifuge rotor for continuous biological treatment
US20230234075A1 (en)*2020-08-142023-07-27Fiberlite Centrifuge LlcContinuous bioprocessing centrifuge rotor

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