US3605738A - Medicinal spray device - Google Patents

Abstract

A DEVICE FOR PRODUCING FROM A PRESSURE VESSEL A PREDETERMINED SPRAY CHARGE CONTAINING AN INHALANT MEDICINE AND A PRESSURIZING AEROSOL, THE VESSEL COMMUNICATING WITH A METERING CHAMBER WHICH, IN TURN, COMMUNICATES WITH A NOZZLE TUBE LOCATED WITHIN AN EJECTION TUBE INTENDED TO BE PLACED IN SUCTION INDUCING RELATION WITH A PATIENT''S MOUTH OR NOSE. A FIRST VALVE CONTROLS FLOW INTO THE METERING CHAMBER AND A SECOND VALVE ATTACHED THERETO CONTROLS FLOW THROUGH THE NOZZLE TUBE AND THE EJECTION OR SUCTION TUBE. THE FIRST VALVE IS MANUALLY OPERATED TO CAUSE A PREDETERMINED QUANTITY OF THE MEDICINE-AEROSOL FLUID TO FILL THE METERING CHAMBER. A PISTON OF LARGE AREA SUPPORTS

THE NOZZLE TUBE AND IS OPERABLE, IN RESPONSE TO SUCTION APPLIED BY THE PATIENT TO THE DISCHARGE TUBE, TO CLOSE THE FIRST VALVE AND OPEN THE SECOND VALVE AND THEREBY CAUSE DELIVERY OF THE MEDICINE-AEROSOL CHARGE TO THE PATIENT''S MOUTH OR NOSE SIMULTANEOUSLY WITH INHALATION. BY MEANS OF A THIRD VALVE, THE METERING CHAMBER MAY ALSO COMMUNICATE MOMENTARILY WITH A CHAMBER CLOSED BY THE PISTON AT ITS SIDE OPPOSITE FROM THE SIDE EXPOSED TO SUCTION PRESSURE SO AS TO SUPPLEMENT THE FORCE EXERTED BY THE PATIENT.

Description

Sept. 20, 1971 p, 1 C|RANNA 3,605,738

MEDICINAL SPRAY DEVICE Filed June 20, 1969 #frog/VEVS UnitedStates Patent O 3,605,738 MEDICINAL SPRAY DEVICE Paul J. Ciranna, 1556 N. Euclid Ave., Upland, Calif. 91780 Filed June 20, 1969, Ser. No. 835,131 Int. Cl. A61m 7l/08 U.S. Cl. 12S-173 2 Claims ABSTRACT OF THE DISCLOSURE A device for producing from a pressure vessel a predetermined spray charge containing an inhalant medicine and a pressurizing aerosol, the vessel communicating with a metering chamber which, in turn, communicates with a nozzle tube located within an ejection tube intended to be placed in suction inducing relation with a patients mouth or nose. A first valve controls flow into the metering chamber and a second valve attached thereto controls ow through the nozzle tube and the ejection or suction tube. The tirst valve is manually operated to cause a predetermined quantity of the medicine-aerosol fluid to lill the metering chamber. A piston of large area supports the nozzle tube and is operable, in response to suction applied by the patient to the discharge tube, to close the first valve and open the second valve and thereby cause delivery of the medicine-aerosol charge to the patients mouth or nose simultaneously with inhalation. By means of a third valve, the metering chamber may also communicate momentarily with a chamber closed by the piston at its side opposite from the side exposed to suction pressure so as to supplement the force exerted by the patient.

BACKGROUND OF THE INVENTION Spray devices which utilize a pressurized aerosol to deliver a charge of a medicine-aerosol to a patients mouth or nose are known. One type utilizes a discharge tube containing a nozzle and a pressure vessel arranged to be pressed toward each other to cause a predetermined quantity of the medicine-aerosol fluid to enter a metering charnber; then, upon release, the charge is ejected.

Heretofore such devices have required that the patient inhale precisely at the time the charge is ejected; otherwise, the medicine is wasted. If the patient manipulates the device, precise timing is less difcult than if an attendant or nurse administers the medicine, providing, however, if the patient has deficient coordination or is semiconscious, the required timing is usually not accomplished.

SUMMARY OF THE INVENTION The present invention provides a solution to this problem and is summarized in the following objects:

First, to provide a medicinal spray device which is so arranged that after the device is manipulated to transfer a predetermined quantity of medicine-aerosol mixture to a metering chamber, the subsequent act of inhalation, when the device is placed in close proximity to the patients mouth or nose, automatically releases the charge; thus, simultaneous inhalation and ejection of the charge is assured.

Second, to provide a medicinal spray device of the type indicated in the preceding object, wherein a portion of the medicine-aerosol charge may be employed to pressurize one side of a piston simultaneous with the application of suction pressure on the other side thereof, thereby minimizing the effort required by the patient.

Third, to provide a medicinal spray device wherein a pressure vessel communicates with a metering chamber which, in turn, communicates with a nozzle tube carried by a piston of large diameter; the nozzle tube being rice mounted in a larger ejection tube to which the piston is exposed, and novel valve means operable by movement of the piston to cause the metering chamber to be charged, then on application of suction to the piston, to open communication between the metering chamber and the nozzle tube.

DESCRIPTION OF THE DRAWINGS FIG. l is an enlarged longitudinal sectional view of the medicinal spray device, with the parts shown in their normal condition', that is, essentially as they appear between uses of the device.

FIG. 2 is a fragmentary sectional View, taken withincircle 2 of FIG. 1.

FIGS. 3, 4, 5 and 6 are fragmentary sectional views, corresponding to FIG. 2, showing succeeding stages of operation of the medicinal spray device.

FIG. 7 is a further enlarged sectional view of the valve member.

FIG. 8 is a further enlarged fragmentary transverse sectional view, taken through 8 8 0f FIG. 1.

SPECIFICATION The medicinal spray device includes apressure vessel 1, having abottom wall 2 containing anoutlet port 3. A body member 4 is joined to thepressure vessel 1 by ascrewthread connection 5.

The upper end of the body member 4 seals against thebottom wall 2 of the pressure vessel and is provided with a central cavity which forms ametering chamber 6. The lower end of the metering chamber is connected by a passage 7 to a relativelylarge piston chamber 8.

Asuction tube 9` is provided which includes a relatively large vertical portion 10, having an external flange 11, which ts slidably in thepiston chamber 8, and is held within thepiston chamber 8 by aretainer ring 12. Thesuction tube 9 also includes ahorizontal portion 13, dimensioned to be presented to a patients mouth or nose.

Centered within the vertical portion 10 of the suction tube is anozzle tube 14, of small diameter, the lower end of which terminates in a nozzle 15, directed horizontally toward the open end of thehorizontal portion 13. The upper end of the nozzle tube extends through the passage 7 and into the metering chamber `6. Formed integrally with thenozzle tube 14 is apiston 16, which fits slidably within thepiston chamber 8, and may be provided with a peripheral lip facing toward the closed end of thechamber 8. A spring 17 is interposed between the anged end of thesuction tube 9 and thepiston 16 so as to urge the piston upwardly toward the closed end of thepiston chamber 8.

Avalve member 18 formed of rubber or other elastomer is received in theoutlet port 3 of the pressure vessel and extends to thenozzle tube 14. The valve member includes a ilanged upper end which engages a correspondingly anged upper end of theoutlet port 3 so as to form therewith a pressure vessel valve means 19. The lower extremity of the valve member is conical and fits a conical recess in the upper end of thenozzle tube 14 to form a nozzle tube valve means 20.

Should increased thrust of thevalve member 18 to close the nozzle tube valve means 20 be desired, aspring 21 is fitted around the valve member, as shown in FIGS. 1 and 7 (the spring being omitted from the other figures). The lower end of the spring is suitably secured to the -valve member 18 adjacent its lower end and the upper end of the spring bears against thebottom Wall 2.

Thenozzle tube 14 iits loosely within the passage 7, and the passage 7 is provided with a channel which receives atransfer valve ring 22. The inner periphery of which sealingly engages thenozzle tube 14. A relatively short axial portion of the nozzle tube is provided with a set ofgrooves 23; that is, the nozzle tube is essentially triangular in cross section in this region, as shown in FIG. 8.

Operation of the medicinal spray device is as follows:

To initiate ruse of the device, the device is held in the position shown in FIG. l; that is, with the pressure vessel above the suction tube. The suction tube is pressed upwardly with respect to the pressure chamber, compressing the spring 17 so as to force thenozzle tube 14 andpiston 16 upwardly through the position shown in FIG. 2 to the position shown in FIG. 3. This operation cocks the medicinal spray device by permitting a charge of the medicine-aerosol mixture to enter themetering chamber 6. The mixture remains in a liquid state or nearly so. When the suction tube is released, the suction tube returns to the position shown in FIG. 1. However, the nozzle tube and piston remain in the position shown in FIG. 3. If the open end of thehorizontal portion 13 of thesuction tube 9 is presented to the patients mouth or nostril, and the patient inhales, a slight vacuum pressure is established in the suction tube and in the region underlying thepiston 16. It will be noted that the area of the piston is quite large so that a relatively small suction pressure will tend to move the piston downwardly from the position shown in FIG. 3 through the positions shown in FIGS. 4 and S to the position shown in FIG. 6. This movement takes place relatively rapidly, but in the course of this movement, there is momentary communication between themetering chamber 6 and the upper side of the piston so that a portion of the liquid medicine-aerosol mixture Within the metering chamber will expand as a gas in the region above thepiston 16, and the force exerted yby the expanded gaseous mixture augments the suction force applied by the patient, thus reducing the effort required by the patient. When thepiston 16 reaches the position shown in FIG. 6, the nozzle tube valve 2.0 opens so that the charge of medicine-aerosol is ejected from the nozzle 1S and into the patients nostril or mouth.

After this operation is completed, thepiston 16 moves upwardly from the position shown in FIG. 6 toward the position shown in PIG. 1 a suicient distance to close thenozzle tube valve 20 without opening thepressure vessel valve 19. It is not intended that thepiston 16 provide an airtight seal with thepiston chamber 8, so that any residual pressure existing above thepiston 16 and in themetering chamber 6 will be gradually relieved until the pressure therein has returned to atmospheric pressure, at which time the spray device is ready for reuse.

While the medicinal spray device is primarily intended for human use, it should be pointed out that in view of the fact that the medicine is discharged automatically when a suction pressure is applied, the dew'ce is uniquely suited for administering the medicine to animals.

It should be noted that the medicine need not be in liquid form, but may be a microine powder suspended in the aerosol.

While a particular embodiment of this invention has been shown and described, it is not intended to limit the same to the details of the construction set forth, but instead, the invention embraces such changes, modications and equivalents of the various parts and their relationships as come within the purview of the appended claims.

I claim:

1. A spray device for medicine-aerosol fluids comprising:

(a) a pressure vessel;

(b) means dening a metering chamber, a relatively large piston chamber and passages connecting said pressure vessel and chambers;

(c) a nozzle tube extending from said metering chamber through said piston chamber and including a piston tting said piston chamber;

(d) an ejection tube surrounding said nozzle tube and having an end slidably received in said piston chamber;

(e) a valve member extending from said pressure vessel to said nozzle tube and including a rst valve means operable to close said pressure vessel and a second valve means operable to close said nozzle tube;

(f) said ejection tube being manually operable to open said first valve means while said second valve means remains closed, thereby to permit a charge of medicine-aerosol fluid to enter said metering chamber, said piston being responsive to suction pressure in said ejection tube to open said second valve means and close said first valve means thereby to cause the medicine-aerosol uid to ow through said nozzle tube and issue from said ejection tube.

2. A spray device, as defined inclaim 1, wherein:

(a) a momentary operable valve means is interposed between said metering chamber and said piston chamber to permit a portion of said medicine-aerosol fluid to enter said piston chamber and exert a force against one side of said piston augmenting the suction force against the other side of said piston.

References Cited UNITED STATES PATENTS 2,992,645 7/1961 'Fowler 12S-208 3,456,644 '7/l969 Thiel 128-l73 RICHARD A. GAUDET, Primary Examiner G. F. DUNNE, Assistant Examiner U.S. Cl. XR.

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