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US3013557A - Combination syringe, shipping container and centrifuge tube - Google Patents

Combination syringe, shipping container and centrifuge tube
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Publication number
US3013557A
US3013557AUS806171AUS80617159AUS3013557AUS 3013557 AUS3013557 AUS 3013557AUS 806171 AUS806171 AUS 806171AUS 80617159 AUS80617159 AUS 80617159AUS 3013557 AUS3013557 AUS 3013557A
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United States
Prior art keywords
cylinder
piston
boss
cap
syringe
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Expired - Lifetime
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US806171A
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Arthur J Pallotta
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Labcorp Early Development Laboratories Inc
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Hazleton Laboratories Inc
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Publication of US3013557ApublicationCriticalpatent/US3013557A/en
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UGE TUBE Dec. 19, 1961 A. J. PALLOTTA COMBINATION SYRINGEZ, SHIPPING CONTAINER AND CEN'I'RIF Filed April 13. 1959 INVENTOR ARTHUR ,J. PALLOTTA BY M M ATTORNEY8 United rates Fatent 3,013 557 (IQMEENATEGN SYRINGEZ SHTPPWG CONTAXNER AND CENTRTEUGE TUBE Arthur- J. Paillotta, Falis Church, Va, assignor to Hazleton Lahorat rites incorporated, Falls Church, Ja., a
corporation of Virginia lFiied Apr. 13, 1959, Ser. No. 8%,171 Claims. 31. 128-218) This invention is directed to an improved syringe construction adaptable as a shipping container and a centriafuge tube.
" An object of this invention is to provide a combined syringe which may be used to take a sample, may be sealed and shipped and later used as a centrifuge container.
Another object of the invention is to provide a syringe having a plastic cylinder of relatively flexible material with an open front end adapted to receive a cap for connection with a hypodermic needle and a tapered rear end apertured to receive a piston rod, there being received in the cylinder a piston of relative rigid material having a squeezing fit with the surrounding flexible wall of the cylinder and a tapered rear end for sealing fit in the tapered rear end of the cylinder.
A further object of the invention is to provide a combination syringe, shipping container and centrifuge tube that may be economically made of plastic material that is easily sterilized for use, scalable for shipping and usable as a centrifuge tube after which it may be thrown away.
A still further object of the invention is to provide a syringe type of container with a flexible wall which has an elastic contracting engagement with a relatively hard piston and wherein a piston rod receiving end has a tapered configuration to seal with a like shaped rear portion of the piston when drawn therein and the other end of the cylinder has a snap fitting engaging means with a cap having snap fitting engagement over the end of the cylinder and a hypodermic needle receiving apertured boss or nipple extending outward therefrom which after detachment of the hypodermic needle may receive a closure cap.
Other objects of this invention will, in part, be obvious and in part appear hereinafter.
This invention is disclosed in the embodiment thereof shown in the accompanying drawing and it comprises the features of construction, combination of elements and arrangement of parts that will be exemplified in the construction hereinafter set forth and the scope of the application of which will be indicated in the appended claims.
For a more complete understanding of the nature and scope of this invention reference can be had to the following detailed description, taken together with the accompanying drawing, in which:
FIG. 1 is a side elevation of this combination syringe;
FIG. 2 is a side elevation of the syringe in section at each end and on an enlarged scale;
FIG. 3 is a closure cap for the hypodermic needle receiving nipple of the syringe;
FIG. 4 is a view along line 4-4 of FIG. 2;
FIG. 5 is a view of a modified form of piston; and
FIG. 6 is a further modified form of piston with the piston rod upper portion broken off.
Throughout the description like reference numbers refer to similar parts.
A syringe according to the invention is generally indicated at 10. It comprises a body member 11 which is cylindrical throughout the greater extent and has a taperedrear end portion 12 decreasing in cross section toward therear end aperture 13 thereof while the front ice end is open and has an outwardly extendingflange 14 thereon. This body member or generally cylindrical member 11 is made of plastic material such as polyethylene as by injection molding or pressure molding. It is of such character that its walls are slightly yieldable and squeeze in against apiston 15 of relatively harder plastic material such as polyethylene or nylon. Other materials may be employed for the cylinder 11 and the piston so long as they are sterilizable and there is a squeezing cooperation between the walls and the piston to insure a suction making fit. Thepiston 15 has a rear portion 15' that is tapered in decreasing circular cross section about mid length of the piston to the rear end. Thistapered piston portion 15 is of like taper to the reartapered portion 12 of the body member 11 and when thepiston 15 is pulled thereinto by thepiston rod 16 attached thereto as a threadedend 16 received in a threadedend aperture 15" in the piston, a seal is formed at the rear end of thesyringe 10. Pistonrod 16 is of somewhat brittle material that may be broken off when a sample of blood, for example, has been drawn into the syringe. Thepiston rod 16 may be of certain selected hardness nylon or even glass. A knob orhand grasp portion 17 may be attached or integrally formed on the outer end ofpiston rod 16.
On the body member 11 conventional indicia volume indications such as 18 may be stamped or etched or formed therein.
Over the front open end and outwardly extendingflange 14 of body member 11 is received acap member 19 having a rearwardly extending shoulder 19' having anannular recess 19" therein that is received by a snap fit engagement over theflanged end 14 of member 11.Cap 19 has a central aperture and an apertured boss ornipple 20 extending from the front face so that the aperture therethrough is in alignment with the aperture in thecap 19. Thenipple 20 has a tapered outer surface, decreasing in cross section from rear to front end and intermediate its length there is formed therein an annular groove 20'. This nipple orboss 20 receives thereon a hypodermic needle such as 22 so that the syringe may be used to take a blood sample or the like.
A cover cap orclosure member 21 is provided to be received over the boss ornipple 20. Thecover cap 21 is formed with an inwardly extending annular lip at its rear end and is tapered so as to be received tightly over theboss 20 after thehypodermic needle 22 has been removed. The lip 21' of thecover cap 21 is received in theannular groove 20 within which it tightly seats and grips.
In practice the hypodermic needle may be left in place on theboss 20 and sealed by binding or by embedding. However, if the needle is removed, thecover cap 21 may be installed over theboss 20.
In FIG. 5 a modified form ofpiston 23 is shown. It is formed with a pair of spaced apart lands 23a which have a diameter slightly in excess of the internal diameter of the cylindrical body portion 11 of the syringe so as to provide a fit which will provide a suction ahead of thepiston 23. The rear end ofpiston 23 at 23b is tapered in a manner lilre tapered portion 15' ofpiston 15. The rear end ofpiston 23 has an apertured axially extending threaded recess therein such as 23c to receive the threaded end 16' ofpiston 16.
in FIG. 6 a further modification of the form apiston 24 may take is illustrated. Here a plurality oflands 24a, such as four, are provided which have a semi-circular shaped peripheral cross section. The reartapered portion 24b serves as a seal with the surroundingtapered wall 12 of the syringe when such a piston as 24 is used. A piston rod in is likewise secured to thepiston 24.
An example of a syringe might be one made according to this invention that has an overall length for member 11 of 3 /4 inches While the inside diameter is .60 of an inch. An example of the size of the cooperatingpiston 15 is one having a diameter of .60 of an inch. In FIG. thepiston 23 may have a diameter of .595 inch while. in FIG. 6, for example, thepiston 24 is made with the diam.- eter of the lands transverse to the axis of the piston as .6312 inch. These respective sizes of the elements have been found to provide a high suction and efficient syringe. An example of-the length of the piston is .50 inch with the tapered portion thereof having a degree included angle.
While the boss has been illustrated, for example, as extending about inch with an included taper angle of-4 degrees, a longer boss may be provided of more flexible material.
This syringe may be. used for most purposes for which a glass syringe is utilized. It is especially advantageous in the collection of blood for bacteriological, chemical, or other clinical studies. The syringe according to the invention is received as a sterile package ready for use. When the blood has been drawn, the unit can be shipped intact to the laboratory, and there the barrel of the Syringe can be used as a container and as a centrifuge tube. It is discarded along with the blood atthe completion of the study.
While the preferred type of combined syringe, shipping container and centrifuge tube has been disclosed as having the container of relatively flexible material and the piston of relatively hard material, it is within the scope of the invention to have the container of relatively hard material, suchas glass material, while the piston is of relatively flexible material as rubber or a suitable plastic composition.
The invention is. claimed as follows:
1. A.medical sampling and specimen container comprising, in combination, a cylinder of an elastic material having an outwardly extending flange at the front open end thereof and a gradually tapering rear end portion decreasing in cross section toward the rear open end; a. plunger having a' relatively rigid head slidable in snug fitting engagement within the. surrounding elastic wall of said cylinder and having substantially the rear half end thereof tapering to be received in a surrounding tapered portion of the cylinder when drawn therein and a plunger rod attached to said plunger head and extending through the rear open end of said cylinder, said plunger rod being of a relatively rigid yet breakable material permitting it to be broken off adjacent the rear end of the cylinder after the plunger head is drawn to the rear and secured in the rear tapered end of the cylinder; and a caphaving a rearwardly extending shoulder with an annular recess therein yieldably received in snap fitting engagement over said outwardly extending flange at the front end of the cylinder, said cap having a forwardly extending boss on the outer face thereof having an axially extending aperture therethrough in communication and alignment with an axially extending aperture through said cap, said boss being adapted to receive a hypodermic needle attachable thereto.
2. A medical sampling and specimen container according to claim 1 including incombination therewith a cover cap received .by and secured on said forwardly projecting boss on said cap of the cylinder.
3. A medical'sampling and specimen container according to claim 1 wherein said tapered rear end of the cylinder tapers down to the aperture thereof which has tight fitting but slidable engagement with said plunger rod.
4. A medical sampling and specimen container according to claim 1 wherein said boss on said cap for the cylinder has a gradual taper from rear end where it joins the cap to forward end and has an annular recess therein intermediate the rear and forward end thereof and a cap for said boss, said cap for the boss having a tapered inner surface and an inwardly extending annular lip at its rear open end, said cap for the boss being received over the boss in close fitting engagement and said inwardly extending lip received within the annular recess of the boss thereby securing the cap on the boss.
5. A medical sampling and specimen container comprising, in combination, a cylinder of an elastic material having an outwardly extending flange at the front open end thereof and a gradually tapering rear end portion decreasing in cross section toward the rear open end; a plunger having a relatively rigid head formed with a plurality of annular lands thereon of larger diameter than the inside diameter of the cylinder and slidably received in snug fitting engagement within the surrounding elastic wall of said cylinder when drawn therein whereby the cylinder wall has generally radially inward gripping engagement on said lands and a plunger rod attached to said plunger head and extending through the rear open end of said cylinder, said rear open end of the cylinder having a radially inwardly extending gripping engagement with said rod, said plunger rod being of a relatively hard yet breakable material permitting it to be broken off adjacent the rear end of the cylinder after the plunger head is drawn to the rear and secured in the rear tapered end of the cylinder; and a cap having a rearwardly extending shoulder with an annular recess therein yieldably received in snap fitting engagement over said outwardly extending flange at the front end of the cylinder, said cap having a forwardly extending boss on the outer face thereof having an axially extending aperture therethrough in communication and alignment with an axially extending aperture through said cap, said boss being adapted to receive a hypodermic needle attachable thereto.
6. A medical sampling and specimen container according to claim 5 wherein said boss on said cap for the cylinder has a gradual taper from rear end where it joins the cap to forward remote end and has an annular recess therein intermediate the rear and forward ends thereof and a cap for said boss when a needle is not attached thereto, said cap for the boss having a tapered inner surface and an inwardly extending annular lip at its rear open end, said cap for the boss being received over the boss in close fitting engagement and said inwardly extending lip received within the annular recess of the boss thereby securing the cap on the boss.
7. A medical sampling and specimen container according to claim 5 wherein the cylinder instead of being of elastic material is of relatively hard material and the plunger instead of being of a relatively rigid material is of a relatively flexible material.
8. A medical sampling and specimen container comprising, in combination, a cylinder having an outwardly extending flange at the front open end thereof and a gradually tapering rear end portion decreasing in cross section toward the rear open end; a plunger having a head slidable in snug fitting engagement within the surrounding wall of the cylinder and having substantially the rear half end thereof tapering to be received in a surrounding tapered portion of the cylinder when drawn therein and a plunger rod attached to said plunger head and extending through the rear open end of said cylinder, said plunger rod being of relatively rigid yet breakable material permitting it to be broken off adjacent the rear end of the cylinder after the plunger head is drawn to the rear and secured in the rear tapered end of the cylinder; and a cap having a rearwardly extending shoulder with an annular recess therein yieldably received in snap fitting engagement over said outwardly extending flange at the front end of the cylinder, said cap having a forwardly extending boss on the outer face thereof having an axially extending aperture therethrough in communication and alignment with an axially extending aperture through said c ceive a hypodermic needle 9. A medical sampli b said boss being adapted to reattachable thereto.
ng and specimen container comprising an elongated hollow member having an opening at positive engagement with said hollow member converging internal wall portion, and a rod member secured to said References Cited in the file of this patent UNITED STATES PATENTS
US806171A1959-04-131959-04-13Combination syringe, shipping container and centrifuge tubeExpired - LifetimeUS3013557A (en)

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Cited By (56)

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Publication numberPriority datePublication dateAssigneeTitle
US3181529A (en)*1962-07-301965-05-04Edgar H WilburnValved body-fluid sampling tubes
US3354882A (en)*1964-10-261967-11-28Pharmaseal LabHypodermic syringe
US3640268A (en)*1965-10-231972-02-08Hugh J DavisMethod and device for biopsy specimen collecting and handling
US3753432A (en)*1971-03-101973-08-21L GuerraHypodermic syringe for blood tests
US3785366A (en)*1961-06-051974-01-15H DavisMethod and apparatus for disease diagnosis
US3937211A (en)*1972-10-271976-02-10Fa. Walter Sarstedt Kunststoff-SpritzgusswerkMulti-purpose syringe
US3962085A (en)*1973-12-191976-06-08Abbott LaboratoriesSkimmer assembly
US4129130A (en)*1975-11-051978-12-12Federico BigarellaVial-syringe
FR2455450A1 (en)*1979-05-031980-11-28Transmed Corp DEVICE FOR TAKING DIAGNOSTIC SAMPLES
US4363329A (en)*1978-01-171982-12-14Concord Laboratories, Inc.Syringe having a reverse-taper barrel
USD271333S (en)1980-10-011983-11-08Wright Laboratories, Inc.Fixed length blood container
US4562844A (en)*1984-11-271986-01-07Jett Labs, Inc.Multipurpose syringe
US4610171A (en)*1985-04-261986-09-09Nason Frederic LUrinanalysis vial
US4722352A (en)*1983-11-151988-02-02Walter Sarstedt Kunststoff-SpritzgusswerkBlood extraction device
US20080145933A1 (en)*2006-12-182008-06-19Patton Richard GSystems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US20090014391A1 (en)*2002-05-032009-01-15Biomet Biologics, LlcBuoy Suspension Fractionation System
US8048321B2 (en)2002-05-242011-11-01Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US8062534B2 (en)2002-05-242011-11-22Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US8119013B2 (en)2007-04-122012-02-21Hanuman, LlcMethod of separating a selected component from a multiple component material
US8187477B2 (en)2002-05-032012-05-29Hanuman, LlcMethods and apparatus for isolating platelets from blood
US8313954B2 (en)2009-04-032012-11-20Biomet Biologics, LlcAll-in-one means of separating blood components
US8328024B2 (en)2007-04-122012-12-11Hanuman, LlcBuoy suspension fractionation system
US8337711B2 (en)2008-02-292012-12-25Biomet Biologics, LlcSystem and process for separating a material
US8535241B2 (en)2011-10-132013-09-17Magnolia Medical Technologies, Inc.Fluid diversion mechanism for bodily-fluid sampling
US8567609B2 (en)2006-05-252013-10-29Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US8591391B2 (en)2010-04-122013-11-26Biomet Biologics, LlcMethod and apparatus for separating a material
US8783470B2 (en)2009-03-062014-07-22Biomet Biologics, LlcMethod and apparatus for producing autologous thrombin
US8808551B2 (en)2002-05-242014-08-19Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US8864684B2 (en)2011-10-132014-10-21Magnolia Medical Technologies, Inc.Fluid diversion mechanism for bodily-fluid sampling
US9011800B2 (en)2009-07-162015-04-21Biomet Biologics, LlcMethod and apparatus for separating biological materials
US9022950B2 (en)2012-05-302015-05-05Magnolia Medical Technologies, Inc.Fluid diversion mechanism for bodily-fluid sampling
US9060724B2 (en)2012-05-302015-06-23Magnolia Medical Technologies, Inc.Fluid diversion mechanism for bodily-fluid sampling
US9149576B2 (en)2012-10-112015-10-06Magnolia Medical Technologies, Inc.Systems and methods for delivering a fluid to a patient with reduced contamination
US9155495B2 (en)2012-11-302015-10-13Magnolia Medical Technologies, Inc.Syringe-based fluid diversion mechanism for bodily fluid sampling
US9204864B2 (en)2012-08-012015-12-08Magnolia Medical Technologies, Inc.Fluid diversion mechanism for bodily-fluid sampling
US9556243B2 (en)2013-03-152017-01-31Biomet Biologies, LLCMethods for making cytokine compositions from tissues using non-centrifugal methods
US9642956B2 (en)2012-08-272017-05-09Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US9701728B2 (en)2008-02-272017-07-11Biomet Biologics, LlcMethods and compositions for delivering interleukin-1 receptor antagonist
US9788774B2 (en)2013-03-122017-10-17Magnolia Medical Technologies, Inc.Methods and apparatus for selectively occluding the lumen of a needle
US9897589B2 (en)2002-05-242018-02-20Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US9895418B2 (en)2013-03-152018-02-20Biomet Biologics, LlcTreatment of peripheral vascular disease using protein solutions
US9950035B2 (en)2013-03-152018-04-24Biomet Biologics, LlcMethods and non-immunogenic compositions for treating inflammatory disorders
US9950084B2 (en)2015-09-032018-04-24Magnolia Medical Technologies, Inc.Apparatus and methods for maintaining sterility of a specimen container
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US10251590B2 (en)2012-12-042019-04-09Magnolia Medical Technologies, Inc.Sterile bodily-fluid collection device and methods
US10576130B2 (en)2013-03-152020-03-03Biomet Manufacturing, LlcTreatment of collagen defects using protein solutions
US10772548B2 (en)2012-12-042020-09-15Magnolia Medical Technologies, Inc.Sterile bodily-fluid collection device and methods
WO2021099628A1 (en)*2019-11-222021-05-27Université Catholique de LouvainDevice for withdrawal and processing of a sample
US11076787B2 (en)2017-09-122021-08-03Magnolia Medical Technologies, Inc.Fluid control devices and methods of using the same
US11234626B2 (en)2015-06-122022-02-01Magnolia Medical Technologies, Inc.Devices and methods for syringe-based fluid transfer for bodily-fluid sampling
US11325117B2 (en)*2017-07-272022-05-10Biomerieux, Inc.Centrifugally separating samples in a container having a seal and containing a plunger for opening the seal
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Cited By (135)

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Publication numberPriority datePublication dateAssigneeTitle
US3785366A (en)*1961-06-051974-01-15H DavisMethod and apparatus for disease diagnosis
US3181529A (en)*1962-07-301965-05-04Edgar H WilburnValved body-fluid sampling tubes
US3354882A (en)*1964-10-261967-11-28Pharmaseal LabHypodermic syringe
US3640268A (en)*1965-10-231972-02-08Hugh J DavisMethod and device for biopsy specimen collecting and handling
US3753432A (en)*1971-03-101973-08-21L GuerraHypodermic syringe for blood tests
US3937211A (en)*1972-10-271976-02-10Fa. Walter Sarstedt Kunststoff-SpritzgusswerkMulti-purpose syringe
US3962085A (en)*1973-12-191976-06-08Abbott LaboratoriesSkimmer assembly
US4129130A (en)*1975-11-051978-12-12Federico BigarellaVial-syringe
US4363329A (en)*1978-01-171982-12-14Concord Laboratories, Inc.Syringe having a reverse-taper barrel
FR2455450A1 (en)*1979-05-031980-11-28Transmed Corp DEVICE FOR TAKING DIAGNOSTIC SAMPLES
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US4722352A (en)*1983-11-151988-02-02Walter Sarstedt Kunststoff-SpritzgusswerkBlood extraction device
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US4610171A (en)*1985-04-261986-09-09Nason Frederic LUrinanalysis vial
US8187477B2 (en)2002-05-032012-05-29Hanuman, LlcMethods and apparatus for isolating platelets from blood
US8950586B2 (en)2002-05-032015-02-10Hanuman LlcMethods and apparatus for isolating platelets from blood
US20090014391A1 (en)*2002-05-032009-01-15Biomet Biologics, LlcBuoy Suspension Fractionation System
US7992725B2 (en)2002-05-032011-08-09Biomet Biologics, LlcBuoy suspension fractionation system
US10393728B2 (en)2002-05-242019-08-27Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US8163184B2 (en)2002-05-242012-04-24Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US8062534B2 (en)2002-05-242011-11-22Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US8808551B2 (en)2002-05-242014-08-19Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US9897589B2 (en)2002-05-242018-02-20Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US8603346B2 (en)2002-05-242013-12-10Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US10183042B2 (en)2002-05-242019-01-22Biomet Manufacturing, LlcApparatus and method for separating and concentrating fluids containing multiple components
US9114334B2 (en)2002-05-242015-08-25Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US8048321B2 (en)2002-05-242011-11-01Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US8567609B2 (en)2006-05-252013-10-29Biomet Biologics, LlcApparatus and method for separating and concentrating fluids containing multiple components
US10052053B2 (en)2006-12-182018-08-21Magnolia Medical Technologies, Inc.Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US10028689B2 (en)2006-12-182018-07-24Magnolia Medical Technologies, Inc.Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US10045724B2 (en)2006-12-182018-08-14Magnolia Medical Technologies, Inc.Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US10028687B2 (en)2006-12-182018-07-24Magnolia Medical Technologies, Inc.Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US8337418B2 (en)2006-12-182012-12-25Magnolia Medical Technologies, Inc.Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US10299713B2 (en)2006-12-182019-05-28Magnolia Medical Technolgies, Inc.Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US8647286B2 (en)2006-12-182014-02-11Magnolia Medical Technologies, Inc.Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
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US8197420B2 (en)2006-12-182012-06-12Magnolia Medical Technologies, Inc.Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
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