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US2541272A - Needle for filling or exhausting ampoules - Google Patents

Needle for filling or exhausting ampoules
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Publication number
US2541272A
US2541272AUS743653AUS74365347AUS2541272AUS 2541272 AUS2541272 AUS 2541272AUS 743653 AUS743653 AUS 743653AUS 74365347 AUS74365347 AUS 74365347AUS 2541272 AUS2541272 AUS 2541272A
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sleeve
hub
cannula
needle
vial
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US743653A
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John T Murphy
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Feb. 13, 1951 J. T. MURPHY NEEDLE FOR FILLING OR EXHAUSTING AMPOULES Filed April 24, 1947 v 342mg@ Patented Feb. 13, 1951 UNITED "STATES yPATE`.1'l\1"l` OFF! NEEDLE FOR FILLING yOR EXHAUSTING iiVILPOULES .John T. :Muriphm Arlington, lMass.
Application Apri1f24, 1947, Serial.No.'7'43,6`53
(Cl. 22B-3192) .7 Claims.
=l My present invention relates vto -needles `Ifor use with vhypoderrnic syringes lor the likeiniilling or -exhausting ampule vialsior like sealed containers. In accordance with my invention, I prov-ide 4a needle'comprising a hub having an axial passage therethrough. `'One -end Aof 'the ihub 'is attac'h'able to the syringe'barrel-with-itspassage lirl-communifcation with Ithe voutlet of ythe fbarrel. One .end 'of a-s'leeve, "the insidediameter of which-is greater than the outside diameter oi the cannula is sealed "tothe cannula adjacent one of its-ends. l@ne part of the axial passage-isjdimensioned'to -receivethe :sleeve and -anotherlpart of V'it is vdimensioned to receive the cannula --and ythe other ends of 'the sleeve Iand cannula lareanchored in the parts of fthe axial passage dimensioned to receive fthem. I lprovide the sleeve and -the hub --with vports so `that when the needle is 'inserted through Athe cover of the vial, air Vthat wouldotherwise intertere `with -the filling or `theexlfiausting of the vial 'through the vcannula -as `the A'syringe plunger is actuatedyis Vfree to flow'th-rough the sleeve.
In the accompanying drawings, -I have lshown -an illustrativefern'bodiment of my 'invention from which its novel features and advantages :Will "be readily apparent.
lIn the drawings:
Fig. 1 shows a needle inaccordance with '-my invention inserted through the rubber'cap rof "an indicatedvial.
Fig. `2 is 'a view lsimilar lto Fig. "l butwiththe needle turned through 90", and
Fig 3 is a section along the A'lines '-3-3 of Fig.`2. y
At 5,'I have indicated 'a Ntypical vial -having 'a rubber 'or like 'closure 6 sealing its mouth. The embodiment of `my invention shown in the drawings, while having other uses, is particularly `adapted for use in lling such containers as thevial 5 with penicillin or streptomycin whichis accomplished .by inserting -a hypodermic needle through its sealed closure and then actuating the yplunger of the syringe to 'discharge a carefully .measured vvolume of "the'liquidinto the vial. In lsuch an operation, airtrapped in the vial A'causes back pressure on theplunger -and'interferes Awith accuracy. As the construction of a hypodermic syringe is widely known, I have indicated only a syringe barrel 1 having a tapered tip 8.
In the embodiment of my invention shown in the drawings, the hub structure of my needle consists of a rst hub 9 having an axial passage I0 tapered at one end as at Il to tightly receive the barrel tip 8 with the axial passage l0 in communication with the interior of the syringe bar- 2 rel 1. At its other lend, the 'hub -9 has a tapered -`nose "I2 which may conveniently be of the same size and shape as the barreltip t. Anchored fin the nose Vl2 is a suitable cannula i3.
At +4, I 'have shown a second hub Vhaving a #nose 15 'and an axial Vpassage i6 extending from its 'rear end through the nose l5. The rear 'end l1 of thefaxial passage It is'dimensioned toreceive the nose -12 Awhich 'is anchored therein to securely lunite thehubsfg and 1li. 'In the Zone'of the nose I5, lthe axial passage 16 -is dimensiones). to receive the -rear of the sleeve' i8, the vinside diameter of which 'is greater than the "outside :diameter of thecannula +3.
The sleeve E23 Vis anchored linthe nose 115 and the cannula lI3 extends therethrough. lAdjacent "the yprotrudingend of thecannula is, the sleeve 'I8 is Yanchored thereto ras at i9 to establish Ya preferably tapering 4juncture to 'enable `the `needle to be readily driventhrough the vial closure 6 without rupturing'it, until the nose AI is substanatially in contact-with the closure '6.
, I have shown the hub lil as having a port '2Q which preferably `is in communication with vthe axial'passage 'IE rearwardly of the anchored end of thesleeve I8 as may be'clearly seen in Figs. l and 3. I lform 'the sleeve 'I8 witha port'2l yand this Ais preferably in the Vform of .a narrow slot as maybe seen in Figs. 2 and'3 'toprevent'its becoming clogged. In practice, thereare Atwo ports 2U and two ports '2l with the ports 2@ and 2l v'being spaced apart 90 relative to each other 'thereby to enable theair passage established by the sleeve "I8 to be eiective'ly cleansed.
In filling or exhausting sealed vials with `a needle in accordance with my invention, it is inserted through the closure 6 substantially to .the
nose l5 o'f the second .hub f4. As the ports 52| are 'then inside the vial '5 and the ports 2i) .are .opento atmosphere, the sleeve i8 serves asa conduit through which air ows into or out of the vial'5 depending onwhether it is ,being exhausted or 'filled'throug-hthe .cannula 13.
'What I therefore claim and desire to secure by LettersPatent is:
.1. Aneedle :for use with a hypodermic or like syringe in filling or exhausting ampule vials or like sealed containers, said needle comprising a hub having an axial passage therethrough and being attachable at one end to the syringe barrel with said passage in communication with the barrel outlet, a cannula to pierce the seal of said vial, a sleeve for said cannula having its inside diameter greater than the outside diametei' of said cannula, one end of said sleeve being sealed to said cannula adjacent one of its ends and the other end of said sleeve terminating short of the other end of said cannula so that a substantial portion of it may extend freely into the vial through the pierced seal, said passage at the other end of said hub being dimensioned to receive said sleeve, another part of said passage being dimensioned to receive said cannula, said other ends of said cannula and said sleeve being entrant of the parts of said passage dimensioned to receive them and being anchored to said hub, and said sleeve and said hub having ports communicating with the interior of said sleeve, the port in said sleeve being located in its vial entering portion.
2. The needle of claim 1 in which there is a chamber in the hub between the parts of the passage Which are dimensioned to receive the sleeve and the cannula andthe port in the hub is in communication with the chamber.
3. The needle of claim 1 in which the port in the sleeve and the port in the hub are disposed at 90 from each other.
4. A needle for use with a hypodermic or like syringe in lling or exhausting vampule vials or like sealed containers, said needle comprising a hub having an axial passage therethrough and being attachable at one end to the syringe barrel with said passage in communication with the barrel outlet, a cannula to pierce the seal of said vial, a sleeve for said cannula having its inside diameter greater than the outside diameter ci said cannula, one end of said sleeve being sealed to said cannula adjacent one of its ends and providing a tapering seal entering joint and the other end of said sleeve terminating short of the other end of said cannula so that a substantial portion of it may extend freely into the vial through the pierced seal, said passage at the other end of said hub being dimensioned to receive said sleeve, another part of said passage being dimensioned to receive said cannula, said other ends of said cannula and said sleeve being entrant of the parts of said passage dimensioned to receive them and being anchored to said hub, and said sleeve having a slot in its vial entering portion in parallelV with its axis and said hub having a port in communication with the interior of said sleeve.
5. A needle for use with a hypodermic or like syringe in lling or exhausting ampule vials o1' like sealed containers, said needle comprising a first hub attachable at one end to the syringe barrel and having an axial passage therethrough in communication with the barrel outlet when the hub is attached to the barrel, a cannula to pierce the seal of said vial and anchored in said hub and protruding from its other end, a second hub having an axial passage extending therethrough of larger diameter than the passage through said rst hub, a sleeve anchored in said second hub and protruding from o-ne end thereof, the other end of said hub being attached to said rst hub with said cannula extending through its passage and said sleeve and protruding, beyond the end thereof, the protruding end of said sleeve being sealed to said cannula adjacent 'its free end so that said sleeve has a vial entering portion of substantial length, and said sleeve and said second hub each having ports, the port 1n said sleeve being located in its vial entering portion.
6. A needle for use with a hypodermic or like syringe in filling or exhausting ampule vials or like sealed containers, said needle comprising a first hub attachable at one end to the syringe barrel and having an axial passage therethrough in communication with the barrel outlet when the hub is attached to the barrel, a cannula t0 pierce the seal of said vial and anchored in said hub and protruding from its other end, a second hub having an axial passage extending therethrough of larger diameter than the passage through said rst hub, a sleeve anchored in said second hub and protruding from one end thereof, said rst hub including a. nose, a portion of said laxial passage through said second hub being dimensioned to receive said nose thereby to 'interconnect said hubs with said cannula extending through said sleeve and protruding beyond the end thereof, the protruding end oi said sleeve being sealed to said cannula adjacent its free end so that said sleeve has a vial entering portion of substantial length, and said sleeve and said second hub each having ports, the port in said sleeve being located in its vial entering portion.
7. A needle for use with a hypodermic or like syringe in filling or exhausting ampule vials or like sealed containers, said needle comprising a rst hub attachable at one end to the syringe barrel and including at its other end a tapered tip and having an axial passage extending from end to end thereof in communication with the barrel outlets when the hub is attached to the barrel, a cannula to pierce the Vseal of said vial and anchored in said tip, a second hub including. a tip and having an axial passage extending therethrough, a sleeve anchored in said tip of said second hub and having its inside diameter greater than the outside diameter of said cannula, said axial passage through said second hub being of greater diameter than that of said sleeve'and including a portion tapered to receive said tip of said first hub and to establish a chamberof substantial size between it and said sleeve, said cannula extending through'said sleeve, said sleeve beinganchored to said cannula adjacent its free end so that said sleeve has a vial entering portion of substantial length and having a slot adjacent its anchored end, and said second hub having a port in communication with said chamber.
JOHN 'I'. MURPHY.
REFERENCES CITED The following references are of record in the le of this patent:
UNITED STATES PATENTS
US743653A1947-04-241947-04-24Needle for filling or exhausting ampoulesExpired - LifetimeUS2541272A (en)

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Cited By (39)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
DE1005685B (en)*1954-08-021957-04-04Dr Walter Brede Device for sterile withdrawal of injection fluid
US2807288A (en)*1954-09-011957-09-24Robert F SheaSterile drop assembly
US2855006A (en)*1955-12-161958-10-07Nat Phoenix Ind IncBeverage containers and method of filling the same
US3063451A (en)*1959-09-281962-11-13Arthur J KowalkSelf-venting type needle
US3074457A (en)*1957-09-161963-01-22Irl I TubbsInflating device
US3202187A (en)*1961-06-081965-08-24Strunck & Co Maschinenfabrik FMeans for cleaning and filling ampoules, bottles and similar containers
US3213669A (en)*1963-02-281965-10-26Wilkens Instr & Res IncAutomatic sample collecting apparatus
US3589470A (en)*1969-09-241971-06-29Superior Mfg CoGrease gun adapter
US3831813A (en)*1973-05-111974-08-27Haemonetics CorpHigh-flow capacity, self-regulating bypass spike
US4231211A (en)*1977-10-251980-11-04Robert Bosch GmbhMethod and apparatus for sealing the fill openings of hard gelatine capsules filled with liquid
US4342341A (en)*1979-02-211982-08-03Southland Instruments, Inc.Blood transfer device
US4543101A (en)*1984-03-281985-09-24Adria Laboratories, Inc.Valve device to aid in reconstituting injectable powders
EP0127781A3 (en)*1983-06-061985-10-30Becton, Dickinson And CompanySelf-venting, non-coring needle assembly
US4559983A (en)*1982-12-291985-12-24Laboratoires Merck Sharp & Dohme ChibretDevice for preparing and dispensing a solution
US4610683A (en)*1985-07-171986-09-09Manresa, Inc.Suction needle
US4723955A (en)*1986-06-021988-02-09Manresa, Inc.Suction needle providing vent capability
US4743243A (en)*1984-01-031988-05-10Vaillancourt Vincent LNeedle with vent filter assembly
DE3800620A1 (en)*1987-03-101988-06-23Michael M Dr Med SchikorskiValve coupling for connection of injection, puncturing and indwelling cannulas to syringes and tubing lines for use in human and veterinary medicine
US5012845A (en)*1988-08-181991-05-07Dynatech Precision Sampling CorporationFluid injector
US5578495A (en)*1994-10-311996-11-26Dynatech Precision Sampling CorporationApparatus, and process, for automatically sampling solids and semi-solids materials for analysis
US5993744A (en)*1994-07-111999-11-30Tekmar CompanyApparatus for introducing standards into a vial
US6426225B1 (en)1994-07-112002-07-30Tekmar CompanyMethod of calibrating a vial autosampler
US20040116892A1 (en)*2001-03-272004-06-17Burroughs Andrew ChristopherKit including side firing syringe needle for preparing a drug in an injection pen cartridge
US20060195069A1 (en)*2004-09-242006-08-31Opie John CPercutaneous diagnostic and therapeutic hematoma drain
US20060200095A1 (en)*2005-03-022006-09-07Steube Gregory ABlunt tip vial access cannula
US7226423B2 (en)*2004-10-222007-06-05Goldenberg Alec SAspiration needle with venting feature
US20070142743A1 (en)*2005-12-162007-06-21Provencher Kevin MTissue sample needle actuator system and apparatus and method of using same
US20070142744A1 (en)*2005-12-162007-06-21Provencher Kevin MTissue sample needle and method of using same
US20080228163A1 (en)*1996-07-172008-09-18Smith James CNeedle venting device for sealed containers
WO2009060486A1 (en)*2007-11-082009-05-14Aea S.R.L.Method for drawing in a liquid product from a bottle by means of a syringe
US20090124998A1 (en)*2003-03-202009-05-14Boston Scientific Scimed, Inc.Method for delivering therapeutic or diagnostic agents
US20090247962A1 (en)*2008-03-312009-10-01Tyco Healthcare Group LpVial Access Device
US8382722B2 (en)2008-06-302013-02-26Covidien LpBlunt tip vial access cannula and method for manufacture
US8480645B1 (en)*2008-08-222013-07-09Sambhu N. ChoudhuryMulti-dose device for insertion into a vial and method of using the same
US20140261861A1 (en)*2013-03-152014-09-18Becton Dickinson and Company LimitedSeal System for Cannula
US9125992B2 (en)2011-09-162015-09-08Melvin A. FinkeFluid delivery device with filtration
US20150352013A1 (en)*2012-12-272015-12-10Medi-Physics, Inc.Needle kit
US11090228B2 (en)*2016-08-192021-08-17Becton Dickinson And CompanyAdapter assembly for attachment to a bottle
US20220219843A1 (en)*2011-04-182022-07-14Dr. Py Institute, LlcNeedle with closure and method

Citations (3)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US1083183A (en)*1912-12-121913-12-30Theopihl BednarowiczBottle-filler.
US2168270A (en)*1936-11-211939-08-01Nat Drug CoHypodermic-injection apparatus
US2416391A (en)*1945-08-181947-02-25Wyeth CorpFluid transfer apparatus

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US1083183A (en)*1912-12-121913-12-30Theopihl BednarowiczBottle-filler.
US2168270A (en)*1936-11-211939-08-01Nat Drug CoHypodermic-injection apparatus
US2416391A (en)*1945-08-181947-02-25Wyeth CorpFluid transfer apparatus

Cited By (54)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
DE1005685B (en)*1954-08-021957-04-04Dr Walter Brede Device for sterile withdrawal of injection fluid
US2807288A (en)*1954-09-011957-09-24Robert F SheaSterile drop assembly
US2855006A (en)*1955-12-161958-10-07Nat Phoenix Ind IncBeverage containers and method of filling the same
US3074457A (en)*1957-09-161963-01-22Irl I TubbsInflating device
US3063451A (en)*1959-09-281962-11-13Arthur J KowalkSelf-venting type needle
US3202187A (en)*1961-06-081965-08-24Strunck & Co Maschinenfabrik FMeans for cleaning and filling ampoules, bottles and similar containers
US3213669A (en)*1963-02-281965-10-26Wilkens Instr & Res IncAutomatic sample collecting apparatus
US3589470A (en)*1969-09-241971-06-29Superior Mfg CoGrease gun adapter
US3831813A (en)*1973-05-111974-08-27Haemonetics CorpHigh-flow capacity, self-regulating bypass spike
US4231211A (en)*1977-10-251980-11-04Robert Bosch GmbhMethod and apparatus for sealing the fill openings of hard gelatine capsules filled with liquid
US4342341A (en)*1979-02-211982-08-03Southland Instruments, Inc.Blood transfer device
US4559983A (en)*1982-12-291985-12-24Laboratoires Merck Sharp & Dohme ChibretDevice for preparing and dispensing a solution
EP0127781A3 (en)*1983-06-061985-10-30Becton, Dickinson And CompanySelf-venting, non-coring needle assembly
US4743243A (en)*1984-01-031988-05-10Vaillancourt Vincent LNeedle with vent filter assembly
US4543101A (en)*1984-03-281985-09-24Adria Laboratories, Inc.Valve device to aid in reconstituting injectable powders
US4610683A (en)*1985-07-171986-09-09Manresa, Inc.Suction needle
US4723955A (en)*1986-06-021988-02-09Manresa, Inc.Suction needle providing vent capability
DE3800620A1 (en)*1987-03-101988-06-23Michael M Dr Med SchikorskiValve coupling for connection of injection, puncturing and indwelling cannulas to syringes and tubing lines for use in human and veterinary medicine
US5012845A (en)*1988-08-181991-05-07Dynatech Precision Sampling CorporationFluid injector
US6544799B1 (en)1994-07-112003-04-08Tekmar CompanyVial autosampler with vial stabilization member
US5993744A (en)*1994-07-111999-11-30Tekmar CompanyApparatus for introducing standards into a vial
US5998217A (en)*1994-07-111999-12-07Tekmar CompanyMethod of introducing standards into a vial
US6040186A (en)*1994-07-112000-03-21Tekmar CompanyVial autosampler with selectable modules
US6056921A (en)*1994-07-112000-05-02Tekmar CompanyVial transporter having an elevator
US6143573A (en)*1994-07-112000-11-07Tekmar CompanyModular vial autosampler
US6426225B1 (en)1994-07-112002-07-30Tekmar CompanyMethod of calibrating a vial autosampler
US5578495A (en)*1994-10-311996-11-26Dynatech Precision Sampling CorporationApparatus, and process, for automatically sampling solids and semi-solids materials for analysis
US20080228163A1 (en)*1996-07-172008-09-18Smith James CNeedle venting device for sealed containers
US7886779B2 (en)*1996-07-172011-02-15Smith James CNeedle venting device for sealed containers
US20040116892A1 (en)*2001-03-272004-06-17Burroughs Andrew ChristopherKit including side firing syringe needle for preparing a drug in an injection pen cartridge
US7195623B2 (en)2001-03-272007-03-27Eli Lilly And CompanyKit including side firing syringe needle for preparing a drug in an injection pen cartridge
US8057459B2 (en)2003-03-202011-11-15Boston Scientific Scimed, Inc.Method for delivering therapeutic or diagnostic agents
US20090124998A1 (en)*2003-03-202009-05-14Boston Scientific Scimed, Inc.Method for delivering therapeutic or diagnostic agents
US20060195069A1 (en)*2004-09-242006-08-31Opie John CPercutaneous diagnostic and therapeutic hematoma drain
US7226423B2 (en)*2004-10-222007-06-05Goldenberg Alec SAspiration needle with venting feature
US8540686B2 (en)2005-03-022013-09-24Covidien AgBlunt tip vial access cannula
US20060200095A1 (en)*2005-03-022006-09-07Steube Gregory ABlunt tip vial access cannula
US20070142743A1 (en)*2005-12-162007-06-21Provencher Kevin MTissue sample needle actuator system and apparatus and method of using same
US20070142744A1 (en)*2005-12-162007-06-21Provencher Kevin MTissue sample needle and method of using same
WO2009060486A1 (en)*2007-11-082009-05-14Aea S.R.L.Method for drawing in a liquid product from a bottle by means of a syringe
US20090247962A1 (en)*2008-03-312009-10-01Tyco Healthcare Group LpVial Access Device
US7981089B2 (en)2008-03-312011-07-19Tyco Healthcare Group LpVial access device
US9713573B2 (en)2008-06-302017-07-25Covidien LpBlunt tip vial access cannula and method for manufacture
US8382722B2 (en)2008-06-302013-02-26Covidien LpBlunt tip vial access cannula and method for manufacture
US8480645B1 (en)*2008-08-222013-07-09Sambhu N. ChoudhuryMulti-dose device for insertion into a vial and method of using the same
US20220219843A1 (en)*2011-04-182022-07-14Dr. Py Institute, LlcNeedle with closure and method
US12097984B2 (en)*2011-04-182024-09-24Dr. Py Institute LlcNeedle with closure and method
US9125992B2 (en)2011-09-162015-09-08Melvin A. FinkeFluid delivery device with filtration
US20150352013A1 (en)*2012-12-272015-12-10Medi-Physics, Inc.Needle kit
US20140261861A1 (en)*2013-03-152014-09-18Becton Dickinson and Company LimitedSeal System for Cannula
US9414990B2 (en)*2013-03-152016-08-16Becton Dickinson and Company Ltd.Seal system for cannula
US20160317389A1 (en)*2013-03-152016-11-03Becton Dickinson and Company Ltd.Seal System for Cannula
US10052259B2 (en)*2013-03-152018-08-21Becton Dickinson and Company Ltd.Seal system for cannula
US11090228B2 (en)*2016-08-192021-08-17Becton Dickinson And CompanyAdapter assembly for attachment to a bottle

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