Movatterモバイル変換


[0]ホーム

URL:


US2186888A - Antiseptic bottle closure - Google Patents

Antiseptic bottle closure
Download PDF

Info

Publication number
US2186888A
US2186888AUS223390AUS22339038AUS2186888AUS 2186888 AUS2186888 AUS 2186888AUS 223390 AUS223390 AUS 223390AUS 22339038 AUS22339038 AUS 22339038AUS 2186888 AUS2186888 AUS 2186888A
Authority
US
United States
Prior art keywords
bottle
closure
air
contents
antiseptic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US223390A
Inventor
Paul E Tullar
Robert C Page
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Burroughs Wellcome Co USA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Burroughs Wellcome Co USAfiledCriticalBurroughs Wellcome Co USA
Priority to US223390ApriorityCriticalpatent/US2186888A/en
Application grantedgrantedCritical
Publication of US2186888ApublicationCriticalpatent/US2186888A/en
Anticipated expirationlegal-statusCritical
Expired - Lifetimelegal-statusCriticalCurrent

Links

Images

Classifications

Definitions

Landscapes

Description

Jan. 9, 1940. P. E. TULLAR fr A. 2,186,888
ANTISBPTIC BOTTLE cLosUnE Filed Aug. 6, 1938 .Pereeiea Jee. 8, 1840 UNITED STATES PATENT OFFICE 2,188,888 Amsmmc noms cLosUnE Application August 6, 1938, Serial No. 223,390
3 Claims.
This invention relates to a bottle closure and more particularly an antiseptic bottle closure to permit the withdrawal of liquid contents by means of a hypodermic needle and syringe.
In injecting various medicines into the body or veins ot a patient, it is necessary that the liquid injected be in a highly sterilized and antiseptic condition and free from contamination by dirt, dust, sporesor bacteria which are in the atmosphere under normal conditions.
An object of the invention is to maintain the sterility of the contents of a bottle during and subsequent to frequent withdrawals of said substances.
Another object 'of the invention is to provide an effective air-tight bottle closure oi' such construction that only filtered air can enter the bot-4 tle and come in contact with the contents thereof. Another object is to permit at all times an l equilibrium er altered er sterilized air with the contents 'of the bottle.
Another object is to maintain equal atmospheric pressure at all times in the bottle, thus allowing rapid withdrawal of the contents.
u Another object is to provide a closure of such construction that the bottle can be held .in any position without loss of uid or leakage of the contents into the lter thus preventing the contents from being concentrated -by evaporation.
l. Although the novel features which are believed to be characteristic of this invention will `be more particularly pointed out in the claims appended hereto, the invention itself may be better understood by referring to the following I, description taken in connection with the accompanying drawing in which speciiic embodiments thereofhave been set forth for purposes of illustration.
In the accompanying drawing,
0' Fig. 1 shows a bottle having .inserted therein an antiseptic closure embodying my invention, together with a hypodermic syringe and a hollow needle withdrawing some of the contents of the bottle;
l Fig. 2 is a top plan view partly broken away;l Fig. 3 is a sectional View of a bottle with the closure in position;
Fig. 4 is a sectional view of a modification thereof.
l0 'I'henumeral 5 denotes a bottle. The closure is made of some pliable, resilient material, preferably rubber, and is circular in form to t tightly into the neck of the bottle. It haswalls 6, a bottom l and achamber 8 containing 'some II absorbent material, preferably sterilized cotton.
The top of the chamber is covered by a ilat, thin sheet of material, preferably rubber, 9, having air vents- I0 to permit 'the ingress of air. At the bottom of the closure there is a groove II extending entirely around the closure. This l' groove II has air vents I2. To the bottom of the closure is secured, and preferably formed integral therewith, a depending ila'p or flange I3. The periphery I4 of the flange I3 isA made of extremely thin and pliable rubber or simi- 10 lar material. l
The operation of the device is as follows. Assuming the bottle 'to be completely lled with the liquid which it is desired to use, there is of course no air in the bottle. The iluid is withl5 drawn, as shown in Fig. 1, by inserting'a h ollow hypodermic needle I5 attached to the syringe I6 of usual construction. As the iluid is withdrawn, the space occupied by the amount withdrawn necessarily has to be filled up with'air. 20 The atmospheric air, by passing through the vents Ill, the sterilizedabsorbent material 8 and the vent holes I2 at thebottom of the closure, passes into the interior I1 of thebottle 5. When a certain amount of fluid has been withdrawn and the bottle placed in an upright or partially upright position, the incoming air will deiiect the lower part Il 'of the ange I3 away from the bottle and allow the air, which has been filtered by coming through the absorbent material, to so enter the bottle, as shown in the modied structure in Fig. 4. When the bottle is inverted or partially inverted, as shown in Fig. 1, the fluid will press the member I4 closely against the side of the' bottle and prevent the contents of the bottle from going into the absorbent material. It will thus be seen that the air in the bottle is at all times in a sterile condition.
It will be noted from Figs. 3 and 4 that thewalls 6 of the structure extend upwardly, as shown in dotted lines in Fig. 4, and are then bent over the lip of the bottle I8 to form a shoulder I9. IWhile the air vent in the upper portion of thestructure 6, shown at I0, is in registry with the upper part of the closure, it will be 5 understood that these vents Ill, as shown in Fig.
4, may be placed anywhere in the top of the structure for conveniencein manufacturing.
The closure is extremely simple and can be placed in the bottle by any unskilled person and can be made to lit bottles of any required size. The bottle can be held in any position Without the use of a long needle to reach the bottom thereof and all the contents of the bottle can be conveniently removed by using the needle. If
there is any alcohol or other disinfectant solution used to rinse the needle and syringe, it does not get into the contents of the bottle because the needle is thoroughly cleansed as it passes through the absorbent cotton.
We claim:
l. An antiseptic bottle closure comprising a stopper made of soft, pliable, impervious material, said stopper having a chamber lled with absorbent sterilized material,v and top and bottom walls above and below said chamber respectively adapted to be punctured by a syringe or the like to permit withdrawal of the contents of the bottle, said stopper having air vents positioned to permit passage of air into said bottle through said absorbent material as the contents of said bottle is removed and means associated with said stopper to prevent escape of liquid into said absorbent material through said air vents when the bottle is held in inverted position.
2. An antiseptic bottle closure comprising a stopper made of soft, pliable, impervious material, said stopper having a chamber filled with absorbent sterilized material, and top and bottom walls above and below said chamber respectively adapted to be punctured by a syringe or the like to permit withdrawal of the contents .through said air vents when the bottle is inverted.
3. An antiseptic bottle closure comprising a stopper made of soft, pliable, impervious material, said stopper having a chamber lled with absorbent sterilized material, and top and bottom walls above and below said chamber respectively adapted to be punctured by a syringe or the like to permit withdrawal of the contents of the bottle, a depending skirt formed on said stopper in a position to engage the inner surface of the bottle, air vents arranged in said stopper to permit passage of air through said absorbent sterilized material and around the outer surface of said skirt into the bottle, said skirt being adapted to close said air vents and prevent reverse passage of liquid into said absorbent material when the bottle is inverted.
PAUL E. TULLAR. ROBERT C. PAGE.
US223390A1938-08-061938-08-06Antiseptic bottle closureExpired - LifetimeUS2186888A (en)

Priority Applications (1)

Application NumberPriority DateFiling DateTitle
US223390AUS2186888A (en)1938-08-061938-08-06Antiseptic bottle closure

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
US223390AUS2186888A (en)1938-08-061938-08-06Antiseptic bottle closure

Publications (1)

Publication NumberPublication Date
US2186888Atrue US2186888A (en)1940-01-09

Family

ID=22836289

Family Applications (1)

Application NumberTitlePriority DateFiling Date
US223390AExpired - LifetimeUS2186888A (en)1938-08-061938-08-06Antiseptic bottle closure

Country Status (1)

CountryLink
US (1)US2186888A (en)

Cited By (26)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US2571015A (en)*1946-10-101951-10-09John C ColumbusCoffee maker
US2661742A (en)*1949-08-131953-12-08Hauduroy PaulMultiple container
US2754866A (en)*1953-01-221956-07-17Republic Molding CorpFlexible containers
US2830722A (en)*1954-01-251958-04-15American Thermos Products CompClosure for vacuum-insulated containers
US2884152A (en)*1953-08-261959-04-28Merck & Co IncVented bottle closure
US2887108A (en)*1953-11-181959-05-19Becton Dickinson CoSyringe assembly
US3946780A (en)*1973-01-041976-03-30Sellers John CFermentation container
US4111326A (en)*1976-03-041978-09-05Becton, Dickinson And CompanyClosure for air evacuated container
US4186840A (en)*1976-03-041980-02-05Becton, Dickinson And CompanyCannulapierceable, self-sealing closure
US4236647A (en)*1979-01-151980-12-02Kotturan Paulson AContainer for sterile liquids
US4261474A (en)*1979-11-011981-04-14Cohen Milton JFilter device for injectable fluids
US4312349A (en)*1979-07-231982-01-26Cohen Milton JFilter device for injectable fluid
FR2496603A1 (en)*1980-12-191982-06-25Seven Holdings Ltd ACCESSORY FOR CONTAINER DESIGNED TO TAKE LIQUID THROUGH HOLLOW NEEDLE OR TUBE
US4671331A (en)*1986-03-131987-06-09Lyphomed, Inc.Cover for medicinal vial
US4700202A (en)*1983-02-231987-10-13Sharp Kabushiki KaishaInk cartridge in an ink jet system printer
US4769026A (en)*1986-08-191988-09-06Erbamont, Inc.Method and apparatus for purging a syringe
US4815619A (en)*1987-07-131989-03-28Turner Thomas RMedicament vial safety cap
US20090178998A1 (en)*2007-12-312009-07-16Keisha Gay KnightClosed cover for medicinal vial
US7824922B2 (en)2001-03-092010-11-02Gen-Probe IncorporatedMethod for removing a fluid substance from a closed system
US20130085466A1 (en)*2009-03-302013-04-04Shinagawa Co., LtdPlug for container
WO2017151248A1 (en)*2016-03-032017-09-08Engage Biotech, Inc.Disinfecting multi-dosage vial cap
US9814650B1 (en)2015-04-202017-11-14Stephen DaileySelf-disinfecting medication vial cap assembly
CN110812573A (en)*2018-08-102020-02-21株式会社吉美医疗Medical infusion set
US11337895B2 (en)*2017-03-242022-05-24Carefusion 303, Inc.Automatic drug compounder with hygroscopic member
US12172803B1 (en)2021-10-042024-12-24Patrick VitelloTamper evident integrated closure
US12383463B1 (en)2020-12-282025-08-12Medical Device Engineering, LlcTamper evident seal for a vial cover

Cited By (39)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US2571015A (en)*1946-10-101951-10-09John C ColumbusCoffee maker
US2661742A (en)*1949-08-131953-12-08Hauduroy PaulMultiple container
US2754866A (en)*1953-01-221956-07-17Republic Molding CorpFlexible containers
US2884152A (en)*1953-08-261959-04-28Merck & Co IncVented bottle closure
US2887108A (en)*1953-11-181959-05-19Becton Dickinson CoSyringe assembly
US2830722A (en)*1954-01-251958-04-15American Thermos Products CompClosure for vacuum-insulated containers
US3946780A (en)*1973-01-041976-03-30Sellers John CFermentation container
US4136794A (en)*1976-03-041979-01-30Becton, Dickinson And CompanyCannula pierceable, self-sealing closure
US4111326A (en)*1976-03-041978-09-05Becton, Dickinson And CompanyClosure for air evacuated container
US4186840A (en)*1976-03-041980-02-05Becton, Dickinson And CompanyCannulapierceable, self-sealing closure
US4187952A (en)*1976-03-041980-02-12Becton, Dickinson And CompanyCannula pierceable, self-sealing closure
US4226333A (en)*1976-03-041980-10-07Becton, Dickinson And CompanyCannula pierceable self-sealing closure
US4290534A (en)*1976-03-041981-09-22Becton, Dickinson And CompanyCannula pierceable self-sealing closure
US4295572A (en)*1976-03-041981-10-20Becton, Dickinson And CompanyCannula pierceable self-sealing closure
US4301936A (en)*1976-03-041981-11-24Becton, Dickinson And CompanyCannula pierceable self-sealing closure
US4236647A (en)*1979-01-151980-12-02Kotturan Paulson AContainer for sterile liquids
US4312349A (en)*1979-07-231982-01-26Cohen Milton JFilter device for injectable fluid
US4261474A (en)*1979-11-011981-04-14Cohen Milton JFilter device for injectable fluids
FR2496603A1 (en)*1980-12-191982-06-25Seven Holdings Ltd ACCESSORY FOR CONTAINER DESIGNED TO TAKE LIQUID THROUGH HOLLOW NEEDLE OR TUBE
US4700202A (en)*1983-02-231987-10-13Sharp Kabushiki KaishaInk cartridge in an ink jet system printer
US4671331A (en)*1986-03-131987-06-09Lyphomed, Inc.Cover for medicinal vial
US4769026A (en)*1986-08-191988-09-06Erbamont, Inc.Method and apparatus for purging a syringe
US4815619A (en)*1987-07-131989-03-28Turner Thomas RMedicament vial safety cap
USRE45194E1 (en)2001-03-092014-10-14Gen-Probe IncorporatedPenetrable cap
US8052944B2 (en)2001-03-092011-11-08Gen-Probe IncorporatedPenetrable cap
US8057762B2 (en)2001-03-092011-11-15Gen-Probe IncorporatedPenetrable cap
US7824922B2 (en)2001-03-092010-11-02Gen-Probe IncorporatedMethod for removing a fluid substance from a closed system
US8685347B2 (en)2001-03-092014-04-01Gen-Probe IncorporatedPenetrable cap
US20090178998A1 (en)*2007-12-312009-07-16Keisha Gay KnightClosed cover for medicinal vial
US8888756B2 (en)*2009-03-302014-11-18Gto Ltd.Plug for container
US20130085466A1 (en)*2009-03-302013-04-04Shinagawa Co., LtdPlug for container
US9814650B1 (en)2015-04-202017-11-14Stephen DaileySelf-disinfecting medication vial cap assembly
WO2017151248A1 (en)*2016-03-032017-09-08Engage Biotech, Inc.Disinfecting multi-dosage vial cap
US11337895B2 (en)*2017-03-242022-05-24Carefusion 303, Inc.Automatic drug compounder with hygroscopic member
US11957641B2 (en)2017-03-242024-04-16Carefusion 303, Inc.Automatic drug compounder with hygroscopic member
CN110812573A (en)*2018-08-102020-02-21株式会社吉美医疗Medical infusion set
US12383463B1 (en)2020-12-282025-08-12Medical Device Engineering, LlcTamper evident seal for a vial cover
US12172803B1 (en)2021-10-042024-12-24Patrick VitelloTamper evident integrated closure
US12195241B1 (en)2021-10-042025-01-14Patrick VitelloTamper evident integrated closure

Similar Documents

PublicationPublication DateTitle
US2186888A (en)Antiseptic bottle closure
US2186908A (en)Air filtering stopper
US2557420A (en)Holder and dispenser for sterile hypodermic needles
US3578037A (en)Method for filling a syringe
US2020828A (en)Hypodermic syringe and closure cap for containers
US2767711A (en)Eye medicament package
US3788369A (en)Apparatus for transferring liquid between a container and a flexible bag
US3354881A (en)Hypodermic needle protector
US1189465A (en)Container for hypodermic solutions.
US5067948A (en)Safety, packaging, injection and disposal system for pre-filled pharmaceutical vials
US4055176A (en)Universal drip chamber and spike assembly
US3030955A (en)Plastic container
US2911123A (en)Bottle cap
US2239275A (en)Self-contained liquid dispensing device
US3881465A (en)Method and apparatus for collecting urine
US3882909A (en)Trans-a-jet 1
US3359977A (en)Air filter means
JPH021276A (en)Plug device of drip bottle
US3208710A (en)Parenteral solution container with supporting means
US2954769A (en)Aseptic liquid transfer apparatus
US2153981A (en)Medicinal container
US4813538A (en)Re-usable sterile parenteral fluid medication administration kit
US2222371A (en)Liquid withdrawal and dispensing means
US2884924A (en)Drip meter
US2816550A (en)Dispensing cap

[8]ページ先頭

©2009-2025 Movatter.jp