US20160209330A1 - Integrated raman spectrometer and modularized laser module - Google Patents

Abstract

An integrated Raman spectrum measurement system and a modularized laser module are provided. The modularized laser module includes a laser emitter and an axis adjustment mechanism. The laser emitter is configured to emit a laser beam. The axis adjustment mechanism is connected to the laser emitter and configured to adjust at least two parameters of axis and orientation of the laser emitter. A beam splitter is disposed on the path of the laser beam. A signal collection unit is for collecting at least a part of a signal light from the beam splitter, wherein the signal light is converting by an object after receiving the part of the laser beam.

Description

CROSS REFERENCE TO RELATED APPLICATION
• This application claims the priority benefit of U.S. provisional application Ser. No. 62/105,752, filed on Jan. 21, 2015. The entirety of the above-mentioned patent application is hereby incorporated by reference herein and made a part of specification.
BACKGROUND OF THE INVENTION
• 1. Field of the Invention
• The invention generally relates to an optical spectrometer and a light source module, in particular, to an integrated Raman spectrum measurement system and a modularized laser module.
• 2. Description of Related Art
• A Raman spectrometer is a spectrometer used to observe vibrational, rotational, and other low-frequency modes in a system. Raman spectrometer is commonly used in chemistry to provide a fingerprint by which molecules can be identified.
• It relies on inelastic scattering, or Raman scattering, of monochromatic light, usually from a laser in the visible, near infrared, or near ultraviolet range. The laser light interacts with molecular vibrations, phonons or other excitations in the system, resulting in the energy of the laser photons being shifted up or down. The shift in energy gives information about the vibrational modes in the system.
• In the recent years, a micro Raman spectrometer is developed. However, the traditional micro Raman spectrometer is huge and has limited choice of laser wavelengths. Moreover, it is hard to adjust and set the positions of the lenses and mirrors in the micro Raman spectrometer.
SUMMARY OF THE INVENTION
• Accordingly, the invention is directed to an integrated Raman spectrum measurement system, which is easy to set and operate.
• The invention is directed to a modularized laser module, which is capable of adjust the position or orientation of a laser emitter in the light path.
• An embodiment of the invention provides an integrated Raman spectrum measurement system configured to measure an object. The integrated Raman spectrum measurement system includes a modularized laser module, a beam splitter, and a signal collection unit. The modularized laser module includes a laser emitter and an axis adjustment mechanism. The laser emitter is configured to emit a laser beam. The axis adjustment mechanism is connected to the laser emitter and configured to adjust at least two parameters of axis and orientation of the laser emitter. The beam splitter is disposed on the path of the laser beam. The signal collection unit is for collecting at least a part of a signal light from the beam splitter, wherein the signal light is converting by the object after receiving the part of the laser beam.
• An embodiment of the invention provides a modularized laser module including a laser emitter, an axis adjustment mechanism, and cooling fins. The laser emitter is configured to emit a laser beam. The axis adjustment mechanism is connected to the laser emitter and configured to adjust at least two parameters of axis and orientation of the laser emitter. The cooling fins are connected to the laser emitter.
• An embodiment of the invention provides a portable integrated Raman spectrum measurement system. The portable integrated Raman spectrum measurement system includes a laser emitter, an axis adjustment mechanism, a beam splitter, a signal collection unit, an illumination device, an image switch module, and an image pickup device. The laser emitter is configured to emit a laser beam. The axis adjustment mechanism is connected to the laser emitter and configured to adjust at least two parameters of axis and orientation of the laser emitter. The beam splitter is disposed on the path of the laser beam. The signal collection unit is for collecting at least a part of a signal light from the beam splitter, wherein the signal light is converted by the object after receiving the part of the laser beam. The illumination device is configured to emit an illumination beam. The image switch module is adapted to be switched into the path of the laser beam or be switched out of the path of the laser beam. The image pickup device is for receiving an image beam from the object when the image switch module is switched into the path of the laser beam.
• In the integrated Raman spectrum measurement system according to the embodiment of the invention, since the axis adjustment mechanism can adjust at least two parameters of axis and orientation of the laser emitter, and the modularized laser module is used, the setting and adjustment of the light path in the integrated Raman spectrum measurement system may be easily achieved by the modularized. As a result, the integrated Raman spectrum measurement system is easy to set and operate. In the modularized laser module, since the axis adjustment mechanism is used, the axes or orientations of the laser emitter in modularized laser module can be adjusted, which improves the applicability of the modularized laser module. In the integrated Raman spectrum measurement system according to the embodiment of the invention, since the image switch module is adapted to be switched into the path of the laser beam or be switched out of the path of the laser beam, a user can easily switch the integrated Raman spectrum measurement system to a measurement mode or an observation mode. As a result, the integrated Raman spectrum measurement system is easy to operate.
BRIEF DESCRIPTION OF THE DRAWINGS
• The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification. The drawings illustrate embodiments of the invention and, together with the description, serve to explain the principles of the invention.
• FIG. 1A is a schematic light path diagram of a Raman spectrometer according to an embodiment of the invention.
• FIG. 1B is a schematic perspective view of the integrated Raman spectrum measurement system inFIG. 1A used in vertical mode.
• FIG. 1C is a schematic perspective view of the integrated Raman spectrum measurement system inFIG. 1A used in horizontal mode.
• FIG. 2 is a schematic view of the modularized laser module inFIG. 1A.
• FIG. 3A is a schematic view of the neutral density filter module inFIG. 1A.
• FIG. 3B is a schematic view of the Raman filter module inFIG. 1A.
• FIG. 4 is a schematic top view of a stage in another embodiment.
• FIG. 5 is a schematic top view of a stage in another embodiment.
• FIG. 6 is a schematic view of an integrated Raman spectrum measurement system according to another embodiment of the invention.
• FIG. 7 is a schematic perspective view of an integrated Raman spectrum measurement system according to another embodiment of the invention.
DESCRIPTION OF THE EMBODIMENTS
• Reference will now be made in detail to the present preferred embodiments of the invention, examples of which are illustrated in the accompanying drawings. Wherever possible, the same reference numbers are used in the drawings and the description to refer to the same or like parts.
• FIG. 1A is a schematic light path diagram of an integrated Raman spectrum measurement system according to an embodiment of the invention,FIG. 1B is a schematic perspective view of the integrated Raman spectrum measurement system inFIG. 1A used in vertical mode, andFIG. 1C is a schematic perspective view of the integrated Raman spectrum measurement system inFIG. 1A used in horizontal mode.FIG. 2 is a schematic view of the modularized laser module inFIG. 1A. Referring toFIGS. 1A-1C and 2, an integrated Ramanspectrum measurement system100 in this embodiment is configured to measure anobject50. The integrated Ramanspectrum measurement system100 includes amodularized laser module200, abeam splitter110, anobjective lens120, and asignal collection unit130. Themodularized laser module200 includes alaser emitter210 and anaxis adjustment mechanism220. Thelaser emitter210 is configured to emit alaser beam212. In this embodiment, thelaser emitter210 is a laser diode or a diode-pumped solid-state (DPSS) laser. However, in other embodiment, thelaser emitter210 may be any other appropriate type of laser. Theaxis adjustment mechanism220 is connected to thelaser emitter210 and configured to adjust at least two parameters of axis and orientation of thelaser emitter210. In this embodiment, theaxis adjustment mechanism220 is configured to move thelaser emitter210 along three axes which are perpendicular to each other. However, in other embodiments, theaxis adjustment mechanism220 may also rotate thelaser emitter210 around three axes which are perpendicular to each other. The aforementioned parameters of axis and orientation means the position parameters include, for example, the three axes of XYZ, and the rotation orientations around any axes. The adjusting at least two parameters of axis and orientation means that thelaser emitter210 may be adjusted at least in the two axes, in one axis and one orientation, or in two orientations, or any combinations thereof.
• Thelaser beam212 is transmitted from thelaser emitter210, and then transmitted into theobject50, a sample to be measured, through thebean splitter110 and theobjective lens120. In one embodiment according to the present invention, theobjective lens120 is a device detachably mounted on the integrated Ramanspectrum measurement system100 on the optical path of thelaser beam212. Thebeam splitter110 is also disposed on the path of thelaser beam212, transmitting at least part of thelaser beam212 to theobject50. In one embodiment, thebeam splitter110 may be a partially transmissive and partially reflective mirror, and in another embodiment, thebeam splitter110 may be a polarizing beam splitter.
• Theobject50 then converts at least part oflaser beam212 into asignal light214. Theobjective lens120 also transmits thesignal light214 to thebeam splitter110 which transmits at least part of thesignal light214 to thesignal collection unit130. In one embodiment, thebeam splitter110 may be the partially transmissive and partially reflective mirror, allowing a part of thesignal light214 to pass through and to be transmitted to thesignal collection unit130.
• In one embodiment, thesignal collection unit130 may be a collimator which collimates thesignal light214 and transmits thesignal light214 to a spectroscope. However, in another embodiment, thesignal collection unit130 may be a spectroscope.
• In one embodiment, a plurality ofmirrors140 disposed on the paths of thelaser beam212 and thesignal light214 turn the paths of thelaser beam212 and thesignal light214.
• Since theaxis adjustment mechanism220 can adjust at least two parameters of axis and orientation of thelaser emitter210, which can significantly reduce to adjust of thebeam splitter110, theobjective lens120, and other optical components, e.g. themirrors140, in the integrated Ramanspectrum measurement system100 As a result, the integrated Ramanspectrum measurement system100 is easy to set and operate.
• In addition, themodularized laser module200 may be easy to be replaced by anothermodularized laser module200 with alaser emitter210 emitting different wavelength. As a result, the integrated Ramanspectrum measurement system100 is easily to be applied in the different measurement with various wavelengths. In one embodiment, themodularized laser module200 can integrated withdifferent laser emitter210 emitting the different wavelength in 405, 473, 488, 532, 633, 785, 808 or 1064 nanometer (nm).
• In one embodiment, themodularized laser module200 further includes coolingfins230 and a coolinggas tube240 to improve the stability and reliability. The coolingfins230 are connected to thelaser emitter210, and the coolinggas tube240 is configured to supply coolinggas242 flowing through the coolingfins230. In an embodiment, a gas pump may be connected to one end of the coolinggas tube240 to supply cooling gas into the coolinggas tube240, and the cooling gas then exits from the other end of the coolinggas tube240 and flows through the coolingfins230.
• In one embodiment, the integrated Ramanspectrum measurement system100 further includes anillumination device150 for providing theillumination beam152, animage switch160 comprising afirst beam splitter164 and asecond beam splitter166, and animage pickup device170. In one embodiment, theillumination device150 may include at least one light-emitting diode (LED). Theimage switch module160 can be switched into or out of the path of thelaser beam212. When theimage switch module160 is switched into the path of thelaser beam212, first beam splitter164 (shown by dotted line inFIG. 1A) reflects at least part of theillumination beam152 to theobject50 through theobjective lens120, then object50 converts the at least part of theillumination beam152 into animage beam154 transmitted to theimage switch module160 through also theobjective lens120, and the second beam splitter166 (shown by dotted line inFIG. 1A) reflects at least part of theimage beam154 to theimage pickup device170. In one embodiment, thefirst beam splitter164 orsecond beam splitter166 is a partially transmissive partially reflective mirror or a polarizing beam splitter.
• In one embodiment, theimage switch module160 further includes aneutral density filter162. When theimage switch module160 is switched into the path of thelaser beam212, the neutral density filter162 (shown by dotted line inFIG. 1A) is also shifted to the path of thelaser beam212 to reduce intensity of thelaser beam212.
• Theimage switch module160 is easy to be switched into or out of the path of thelaser beam212, making users easily switch the integrated Raman spectrum measurement system to a measurement mode or an observation mode. Specifically, in the measurement mode, theneutral density filter162, thefirst beam splitter164 and thesecond beam splitter166 are located at the positions of the solid lines inFIG. 1A, so that thesignal light214 may be transmitted to thesignal collection unit130, and the Raman signal of theobject50 may be measured. In the observation mode, theneutral density filter162, thefirst beam splitter164 and thesecond beam splitter166 are located at the positions of the dotted lines inFIG. 1A, so that theimage beam154 may be transmitted to theimage pickup device170, and the image of theobject50 may be observed by the user through theimage pickup device170. In one embodiment, theimage pickup device170 is, for example, a camera. In another embodiment, theimage pickup device170 may be replaced by an eyepiece, so that the user may observe the image of theobject50 through the eyepiece.
• In one embodiment, the integrated Ramanspectrum measurement system100 further includes a neutraldensity filter module330 disposed on the path of thelaser beam212 between thelaser emitter210 and thebeam splitter110, as shown inFIGS. 1A and 3A. The neutraldensity filter module330 includes a plurality ofneutral density filters332a,332b,332chaving different transmittance and configured to be selectively switched into the path of thelaser beam212. For example, theneutral density filter332amay have the transmittance of 1/2, theneutral density filter332bmay have the transmittance of 1/10, and theneutral density filter332cmay have the transmittance of 1/100. Moreover, the neutraldensity filter module330 may also have ahole332 having the transmittance of 100%. Theneutral density filters332a,332b,and332cand thehole332 may be switched into the path of thelaser beam212, so as to adjust the intensity of thelaser beam212. The number of theneutral density filters332a,332b, and332cin the neutraldensity filter module330 is not limited to 3. In other embodiment, the number of the neutral density filter(s) may be any natural number other than 3.
• In one embodiment, the integrated Ramanspectrum measurement system100 further includes aRaman filter module340 disposed on a path of thesignal light214 between thebeam splitter110 and thesignal collection unit130, as shown inFIGS. 1A and 3B. TheRaman filter module340 includes a plurality offilters342a,342b,342c, and342dwith different transmittance spectra, each of thefilters342a,342b,342c,and342dis configured to filter out light having a wavelength range corresponding to the peak wavelength of thelaser beam212 ofdifferent laser emitter210, and thefilters342a,342b,342c,and342dare configured to be selectively switched into the path of thesignal light214. For example, when the peak wavelength of thelaser beam212 is 473 nm, thefilter342acapable of filtering out the light having the wavelength of 473 nm may be selected to switch into the path of thesignal light214 so as to filter out the portion having the wavelength of 473 nm in thesignal light214. The number of the filters in theRaman filter module340 is not limited to 4. In other embodiments, the number of the filter(s) may be any natural number other than 4.
• In one embodiment, the integrated Ramanspectrum measurement system100 further includes ahousing180, a pedestal310 (seeFIG. 1B), and a stage320 (seeFIG. 1B). Thehousing180 contains themodularized laser module200, thebeam splitter110, and thesignal collection unit130. In one embodiment, thehousing180 may further contains theimage switch module160, theillumination device150, theimage pickup device170, and theminors140. Thepedestal310 is detachably connected to thehousing180, and thestage320 is movably connected to thepedestal310 and configured to carry theobject50. When thepedestal310 is attached to thehousing180 as shown inFIG. 1B, the integrated Ramanspectrum measurement system100 is used to measure theobject50 in a vertical mode. When thepedestal310 is detached from thehousing180 as shown inFIG. 1C, the integrated Ramanspectrum measurement system100 is used to measure theobject50 in a horizontal mode.
• In one embodiment, the integrated Ramanspectrum measurement system100 further includes acontrol unit350 and alocating mechanism360. Thecontrol unit350 is electrically connected to theimage pickup device170, and thelocating mechanism360 is electrically connected to thecontrol unit350. Thestage320 connected to thelocating mechanism360. When a user selects a measuring point P on ascreen60 electrically connected to thecontrol unit350, thecontrol unit350 commands thelocating mechanism360 to move thestage320 so that the measuring point P is shown in a central portion or a setting portion on thescreen60. In this embodiment, the user can select the measuring point P by using a mouse, a touch pen, finger touching, etc. Moreover the image shown on thescreen60 is the image detected by theimage pickup device170.
• In one embodiment, a calibration plate having, for example, a smooth surface may be disposed on thestage320 first. The calibration plate may reflects thelaser beam212, so that there is a clear light spot on thescreen60. Then, the user may selects the clear light spot as the measuring point P and mark the measuring point P. After that, the calibration plate is replaced by theobject50, and the position of the mark on the image of theobject50 is the measuring point P of theobject50. That is, the measured Raman signal is from the measuring point P of theobject50. The user may manually or automatically move thestage320, so that the position on theobject50 which is regarded as the measuring point P is changed.
• The integrated Ramanspectrum measurement system100 in this embodiment has the characteristic of small size, flexible wavelength switching, and in-situ analysis. The integrated Ramanspectrum measurement system100 can be applied to very small samples, built in surface enhanced Raman scattering technique, and the Raman spectra can be measured through quartz, glass, plastic.
• FIG. 4 is a schematic top view of a stage in another embodiment. Referring toFIGS. 1A, 1B, 2, and 4, in this embodiment, the integrated Ramanspectrum measurement system100 further includes atrigger370 disposed on thestage320. When theobject50 is disposed on thestage320, thetrigger370 turns on thelaser emitter210 to emit thelaser beam212. In this embodiment, theobject50 is disposed on amicroslide70, and aconductive line72 is formed on themicroslide70. When themicroslide70 is disposed on thestage320 and theconductive line72 touches thetrigger370, a closed circuit is formed so as to turns on thelaser emitter310 and the spectroscope connected to or located on thesignal collection unit130. That is, when theobject50 is disposed on thestage320, the measurement is automatically started. In another embodiment, thetrigger370 may be a button, and when themicroslide70 is disposed on thestage320, themicroslide70 presses the button, so as to turn on thelaser emitter310 and the spectroscope.
• FIG. 5 is a schematic top view of a stage in another embodiment. Referring toFIG. 5, in this embodiment, thestage320′ is configured to supply an electric voltage or current to theobject50. Specifically, in this embodiment, themicroslide70′ may be a conductive microslide or have a conductive patterns, and theelectrodes322′ of thestage320′ supply the electric voltage or current to themicroslide70′ so as to supply the electric voltage or current to theobject50. The electric voltage or current may activate theobject50, such as a bio-sample, so as to enhance the spectral signal of the bio-sample. Moreover, through theelectrodes322′, the integrated Ramanspectrum measurement system100 may read the information of the bio-sample.
• FIG. 6 is a schematic view of an integrated Raman spectrum measurement system according to another embodiment of the invention. Referring toFIG. 6, the integrated Ramanspectrum measurement system100ain this embodiment is similar to the integrated Ramanspectrum measurement system100 shown inFIG. 1B, and the main difference therebetween is as follows. In this embodiment, the integrated Ramanspectrum measurement system100afurther includes abarcode scanner380 configured to detect abarcode74 of theobject50. Thebarcode scanner380 may be electrically connected to thecontrol unit350, and thecontrol unit350 may identify theobject50 through thebarcode74. The measuring result can be integrated with the sample information in the barcode, and is then sent to a database. Thebarcode74 may be a one-dimensional barcode or a two dimensional barcode, e.g. a quick response code (QR code). In another embodiment, thebarcode74 may be detected by theobjective lens120 and theimage pickup device170, and the integrated Ramanspectrum measurement system100 does not have thebarcode scanner380.
• FIG. 7 is a schematic perspective view of an integrated Raman spectrum measurement system according to another embodiment of the invention. Referring toFIGS. 1A, 1B, and 7, in this embodiment, thepedestal310 is configured to serve as acase390 of the integrated Ramanspectrum measurement system100 to contain thestage320 and thehousing180. For example, thepedestal310 may be transformed into thecase390, and thecase390 may serve as a corrosion prevention box. In another embodiment, thepedestal310, thestage320, and thehousing180 may be put into thecase390 serving as a corrosion prevention box. As a result, the integrated Ramanspectrum measurement system100 may be portable.
• In conclusion, in the integrated Raman spectrum measurement system according to the embodiment of the invention, the modularized laser module is used and integrated with the axis adjustment mechanism to only adjust few parameters of axis and orientation of the laser emitter to easily achieve the setting and adjustment of the light path in the integrated Raman spectrum measurement system. In the integrated Raman spectrum measurement system according to the embodiment of the invention, since the image switch module is adapted to be switched into the path of the laser beam or be switched out of the path of the laser beam, a user can easily switch the integrated Raman spectrum measurement system to a measurement mode or an observation mode. As a result, the integrated Raman spectrum measurement system is easy to operate.
• It will be apparent to those skilled in the art that various modifications and variations can be made to the structure of the invention without departing from the scope or spirit of the invention. In view of the foregoing, it is intended that the invention cover modifications and variations of this invention provided they fall within the scope of the following claims and their equivalents.

Claims (20)

What is claimed is:

1. An integrated Raman spectrum measurement system configured to measure an object, the integrated Raman spectrum measurement system comprising:

a modularized laser module comprising:

a laser emitter configured to emit a laser beam;

an axis adjustment mechanism connected to the laser emitter and configured to adjust at least two parameters of axis and orientation of the laser emitter;

a beam splitter disposed on a path of the laser beam; and

a signal collection unit, for collecting at least a part of a signal light from the beam splitter, wherein the signal light is converting by the object after receiving the part of the laser beam.

2. The integrated Raman spectrum measurement system according toclaim 1 further comprising:

an objective lens, for transmitting at least part of the laser beam through the beam splitter to the objective lens, and receiving signal light from the object then sending to the beam splitter.

3. The integrated Raman spectrum measurement system according toclaim 1 further comprising:

an illumination device configured to emit an illumination beam;

an image switch module adapted to be switched into the path of the laser beam or be switched out of the path of the laser beam; and

an image pickup device, for receiving an image beam from the object when the image switch module is switched into the path of the laser beam.

4. The integrated Raman spectrum measurement system according toclaim 3, wherein the image switch module comprises a neutral density filter, and wherein when the image switch module is switched into the path of the laser beam, the neutral density filter is switched into the path of the laser beam to reduce intensity of the laser beam.

5. The integrated Raman spectrum measurement system according toclaim 4, wherein the image switch module further comprises:

a first beam splitter, wherein when the image switch module is switched into the path of the laser beam, the first beam splitter transmits the at least part of the illumination beam to the objective lens; and

a second beam splitter, wherein when the image switch module is switched into the path of the laser beam, the second beam splitter transmits the at least part of the image beam to the image pickup device.

6. The integrated Raman spectrum measurement system according toclaim 3 further comprising:

a control unit electrically connected to the image pickup device;

a locating mechanism electrically connected to the control unit; and

a stage carrying the object and connected to the locating mechanism, wherein when a user selects a measuring point on a screen electrically connected to the control unit, the control unit commands the locating mechanism to move the stage so that the measuring point is shown in a central portion or a setting portion on the screen.

7. The integrated Raman spectrum measurement system according toclaim 1 further comprising a neutral density filter module disposed on the path of the laser beam between the laser emitter and the beam splitter, wherein the neutral density filter module comprises a plurality of neutral density filters having different transmittance and configured to be selectively switched into the path of the laser beam.

8. The integrated Raman spectrum measurement system according toclaim 1 further comprising a Raman filter module disposed on a path of the signal light between the beam splitter and the signal collection unit, wherein the Raman filter module comprises a plurality of filters with different transmittance spectra, each of the filters is configured to filter out light having a wavelength range corresponding to the peak wavelength of the laser beam of different laser emitter, and the filters are configured to be selectively switched into the path of the signal light.

9. The integrated Raman spectrum measurement system according toclaim 1, wherein the modularized laser module further comprises:

cooling fins connected to the laser emitter; and

a cooling gas tube configured to supply cooling gas flowing through the cooling fins.

10. The integrated Raman spectrum measurement system according toclaim 9 further comprising:

a trigger disposed on the stage, wherein when the object is disposed on the stage, the trigger turns on the laser emitter to emit the laser beam.

11. The integrated Raman spectrum measurement system according toclaim 9, wherein the stage is configured to supply an electric voltage or current to the object.

12. The integrated Raman spectrum measurement system according toclaim 9, wherein the pedestal is configured to serve as a case of the integrated Raman spectrum measurement system to contain the stage and the housing.

13. The integrated Raman spectrum measurement system according toclaim 1 further comprising a barcode scanner configured to detect a barcode of the object.

14. A modularized laser module comprising:

a laser emitter configured to emit a laser beam;

an axis adjustment mechanism connected to the laser emitter and configured to adjust at least two parameters of axis and orientation of the laser emitter; and

cooling fins connected to the laser emitter.

15. The modularized laser module according toclaim 14, wherein the modularized laser module is configured to insert into a Raman spectrometer.

16. The modularized laser module according toclaim 14 further comprising:

a cooling gas tube configured to supply cooling gas flowing through the cooling fins.

17. A portable integrated Raman spectrum measurement system, comprising:

a laser emitter configured to emit a laser beam;

an axis adjustment mechanism connected to the laser emitter and configured to adjust at least two parameters of axis and orientation of the laser emitter;

a beam splitter disposed on the path of the laser beam;

a signal collection unit, for collecting at least a part of a signal light from the beam splitter, wherein the signal light is converted by the object after receiving the part of the laser beam;

an illumination device configured to emit an illumination beam;

an image switch module adapted to be switched into the path of the laser beam or be switched out of the path of the laser beam; and

an image pickup device, for receiving an image beam from the object when the image switch module is switched into the path of the laser beam..

18. The integrated Raman spectrum measurement system according toclaim 17, wherein the image switch module comprises a neutral density filter, and wherein when the image switch module is switched into the path of the laser beam, the neutral density filter is switched into the path of the laser beam to reduce intensity of the laser beam.

19. The integrated Raman spectrum measurement system according toclaim 18, wherein the switch module further comprises:

a first beam splitter, wherein when the image switch module is switched into the path of the laser beam, the first beam splitter transmits the at least part of the illumination beam to the objective lens; and

a second beam splitter, wherein when the image switch module is switched into the path of the laser beam, the second beam splitter transmits the at least part of the image beam to the image pickup device.

20. The integrated Raman spectrum measurement system according toclaim 17 further comprising:

a control unit electrically connected to the image pickup device;

a locating mechanism electrically connected to the control unit; and

a stage carrying the object and movably connected to the locating mechanism, wherein when a user selects a measuring point on a screen electrically connected to the control unit, the control unit commands the locating mechanism to move the stage so that the measuring point is shown in a central portion or a setting portion on the screen.

Images