US20140052273A1 - Filler for removing wrinkles - Google Patents

Abstract

The present invention relates to a filler for removing wrinkles, which comprises: a thin and long tubular main body to be placed so as to penetrate through subcutaneous tissue; and through-holes for guiding tissue cells surrounding the main body into the main body, so as to form fibrous tissue, wherein the through-holes are formed so as to communicate with a hollow portion formed in said main body in the lengthwise direction from the outer surface of said main body. The filler for removing wrinkles according to the present invention is prevented from being deformed or moved by pressure on the skin or by an external force arising after being inserted into the subcutaneous tissue, and can be applied to various body parts having wrinkles, including deep wrinkles. Furthermore, the wrinkle-removing effects of the filler of the present invention may last (semi)permanently.

Description

TECHNICAL FIELD
• The present disclosure relates to a filler for removing wrinkles, more particularly to a filler which is inserted into the subcutaneous layer around wrinkles through cosmetic surgery and removes the wrinkles by inducing formation of new fibrous tissue.
BACKGROUND ART
• As human ages, wrinkles are formed on the skin surface of the face or body. The wrinkles are formed because of muscular contraction. The wrinkles are formed perpendicularly to the direction of muscle contraction and become deeper with aging.
• As a method for removing wrinkles, Botox is frequently used to paralyze the muscles which cause wrinkles. However, this results in an unnatural look and is limited in removing the wrinkles below the eyes, below the lower lip and around the mouth and in removing thick or deep wrinkles. Also, the effect lasts only 3-6 months.
• As another method, a filler is used to correct wrinkles and other depressions in the skin. Although a liquid filler is convenient to inject, it tends to move toward the direction of muscle contraction after being injected into the skin. As a result, the wrinkles may look deeper and, it is limited in that it is degraded and absorbed by the body after a predetermined time (up to about 1-2 years).
• Another method is to insert a very thin gold thread into the subcutaneous layer. The gold thread induces growth of new tissue around the thread through foreign body reactions. However, this method is limited to be used for thick wrinkles and the inserted gold thread may be bent by external force or protrude out of the skin. Also, it may cause diagnostic problems during X-ray, CT or MRI imaging through interference.
DISCLOSURETechnical Problem
• The present disclosure is directed to providing a filler for removing wrinkles that is not moved after being inserted into the subcutaneous layer without resorting, for example, to surgical skin incision regardless of muscle contraction.
• The present disclosure is also directed to providing a filler for removing wrinkles that provides (semi)permanently lasting wrinkle-removing effect after being inserted into the subcutaneous layer even when the filler itself is degraded and absorbed by the body with time since it induces formation of new fibrous tissue including collagen fiber.
• The present disclosure is also directed to providing a filler for removing wrinkles that can be applied to various wrinkles including thick wrinkles and has recoiling force against external force.
Technical Solution
• In a general aspect, there is provided a filler for removing wrinkles, including: a thin and long tubular main body provided so as to penetrate the subcutaneous layer; and through-holes provided so as to guide tissue cells surrounding the main body into the main body to form fibrous tissue, wherein the through-holes are formed to communicate with a hollow portion formed in the main body in a lengthwise direction from the outer surface of the main body.
• In an exemplary embodiment of the present disclosure, the main body of the filler for removing wrinkles has a circular transection.
• Specifically, the main body may have an outer diameter of 0.6-1.0 mm, the hollow portion may have a diameter (inner diameter of the main body) of 0.5-0.7 mm, and the through-holes may have a diameter of 40-500 μm.
• In an exemplary embodiment of the present disclosure, the main body of the filler for removing wrinkles is made of an elastic material.
• In another exemplary embodiment of the present disclosure, the main body of the filler for removing wrinkles is made of a biodegradable polymer selected from a group consisting of hyaluronic acid (HA), polylactic acid (PLA), polyglyco-lactic acid (PGLA) and polydioxanone (PDS).
• In another exemplary embodiment of the present disclosure, the main body of the filler for removing wrinkles is made of a non-biodegradable polymer selected from a group consisting of nylon, silicone and Teflon.
• In another exemplary embodiment of the present disclosure, the main body may have a double-layer structure including an inner sheath and an outer sheath made of different materials having different physical properties.
• In another exemplary embodiment of the present disclosure, a plurality of partitions may be further formed in the hollow portion in the main body of the filler for removing wrinkles.
• In another exemplary embodiment of the present disclosure, a spiral elastic support may be further formed in the hollow portion in the main body of the filler for removing wrinkles.
• In another exemplary embodiment of the present disclosure, a spiral elastic support may be provided outside the main body of the filler for removing wrinkles so as to surround the outer surface of the main body.
Advantageous Effects
• Since a filler for removing wrinkles according to the present disclosure has recoiling force, it is not deformed or moved by the pressure or external force applied on the skin after being inserted into the subcutaneous layer. Since a large quantity of new fibrous tissue including collagen fiber can be formed in a hollow portion of a main body of the filler through through-holes provided on the outer surface of the main body, the filler can be applied to various wrinkles including thick wrinkles by adjusting the diameter of the main body, the diameter of the hollow portion, the diameter of the through-holes, etc. depending on the size and kind of the wrinkles. Furthermore, the wrinkle-removing effect may last (semi)permanently since new fibrous tissue is formed.
DESCRIPTION OF DRAWINGS
• FIG. 1 is a perspective view of a filler for removing wrinkles according to an exemplary embodiment of the present disclosure.
• FIG. 2 is a perspective view of a filler for removing wrinkles according to another exemplary embodiment of the present disclosure.
• FIG. 3 is a longitudinal sectional view of a filler for removing wrinkles according to another exemplary embodiment of the present disclosure wherein partitions are formed.
• FIG. 4 is a longitudinal sectional view of a filler for removing wrinkles according to another exemplary embodiment of the present disclosure wherein a spiral elastic support is provided.
• FIG. 5 shows fibrous tissue formed in a hollow portion of a filler for removing wrinkles according to the present disclosure inserted into the subcutaneous layer.
• FIG. 6 shows a filler for removing wrinkles according to another exemplary embodiment of the present disclosure which is improved to allow easy insertion into a curved part.
• FIG. 7 shows the filler for removing wrinkles according to the embodiment shown inFIG. 6 which is inserted into a curved part.
• FIG. 8 shows a filler for removing wrinkles according another exemplary embodiment of the present disclosure wherein elastic cogs projecting in one direction are provided on the outer surface of a main body of the filler for removing wrinkles.
• FIG. 9 shows the filler for removing wrinkles according to the embodiment shown inFIG. 8 being inserted into the subcutaneous layer.
• FIG. 10 shows the filler for removing wrinkles according to the embodiment shown inFIG. 8 inserted into the subcutaneous layer.
MODE FOR INVENTION
• Hereinafter, the embodiments of the present disclosure will be described in detail referring to the attached drawings.
• FIG. 1 is a perspective view of a filler for removing wrinkles according to an exemplary embodiment (first embodiment) of the present disclosure. As shown inFIG. 1, afiller10 for removing wrinkles according to the present disclosure includes: a thin and long, integral tubularmain body12 provided so as to penetrate the subcutaneous layer; and through-holes14 provided so as to guide tissue cells surrounding themain body12 into themain body12 to form fibrous tissue, wherein the through-holes14 are formed to communicate with ahollow portion12cformed in themain body12 in a lengthwise direction from the outer surface of themain body12.
• In another exemplary embodiment (second embodiment) of the present disclosure shown inFIG. 2, thefiller10 for removing wrinkles may have, for example, a circular transection (Also, it may have a hexagonal transection.). The thin and long tubularmain body12 may be formed by spirally winding a plurality of strip-shaped parts12a,12bwhich is made of the material of themain body12 of thefiller10 for removing wrinkles and which is having a predetermined width b along the surface of along core material20 having a diameter desired for thehollow portion12cso as to cross each other (in a manner similar to making a bamboo wife from bamboo cane). Then, thecore material20 may be removed, such that thehollow portion12cis formed in theparts12a,12bin a lengthwise direction, and the through-holes14 may be formed by the gaps between theparts12a,12b(including the gaps formed at the crossing of the parts). Alternatively, the thin and long tubularmain body12 may be formed by various methods which are spirally winding the plurality ofparts12a,12bso as to cross each other, without using the core material. AlthoughFIG. 2 shows an example wherein twoparts12a,12b,i.e. afirst part12aand asecond part12b,are used to form thefiller10 for removing wrinkles according to the present disclosure, it will be obvious to those skilled in the art that the thin and long tubularmain body12 may be formed by spirally winding a plurality of strip-shaped parts as to cross each other, without being limited thereto.
• In the exemplary embodiments of the present disclosure including the first embodiment and the second embodiment described above, themain body12 may have a circular or polygonal (e.g., tetragonal, hexagonal, octagonal, etc.) transection. Specifically, it may have a circular transection, so that it can be easily inserted into the subcutaneous layer after being threaded on a needle (e.g., a needle for cosmetic surgery). Specifically, themain body12 may have a diameter of 0.6-1.0 mm, so that it can be easily inserted into the subcutaneous layer and be located between the subcutaneous fat layer and the dermis or in the fat layer after being inserted. The length of themain body12 is not particularly limited as long as it is enough for insertion.
• Thehollow portion12cformed in themain body12 in the lengthwise direction provides a space, so that nearby tissue cells such as fibroblasts are guided through the through-holes14 and then fibrous tissue such as elastic fibrous tissue and collagen tissue is newly formed. Accordingly, since the amount of newly formed fibrous tissue increases as the diameter of thehollow portion12cis larger and the amount of newly formed fibrous tissue decreases as the diameter of thehollow portion12cis smaller, the diameter of thehollow portion12cmay be adequately adjusted depending on the depth, location, etc. of wrinkles. In general, the diameter of thehollow portion12cmay be 0.5-0.7 mm.
• The through-holes14 provide a passage for fibroblasts, etc. to enter thehollow portion12c.They may have any shape, including circular, triangular, tetragonal, octagonal, trapezoidal and rhombic shapes. The plurality of through-holes14 may be arranged regularly or irregularly on the outer surface of themain body12. Specifically, the through-holes14 may have a diameter, when they have a circular shape, or a circle-equivalent diameter, when they have other shapes, of 40-500 μm. If the diameter is too large, thefiller10 may not be able to support the surrounding tissues.
• Specifically, themain body12 may be made of an elastic material. It may be made of a biodegradable polymer such as hyaluronic acid (HA), polylactic acid (PLA), polyglyco-lactic acid (PGLA) and polydioxanone (PDS) or a non-biodegradable polymer such as nylon, silicone and Teflon. If a biodegradable polymer is used, the filler for removing wrinkles is slowly degraded and absorbed after the fibrous tissue is formed. If a non-biodegradable polymer is used, the filler for removing wrinkles remains permanently in the subcutaneous layer.
• Themain body12 may have a double-layer structure including an inner sheath and an outer sheath made of different materials having different physical properties. For example, the inner sheath may be formed of a hard material and the outer sheath may be formed of a soft material. Alternatively, the inner sheath may be formed of an absorbent material and the outer sheath may be formed of a non-absorbent material, or the inner sheath and the outer sheath may be formed of absorbent materials having different rate of absorption.
• The filler for removing wrinkles according to the present disclosure has recoiling force so as to endure the pressure or external force applied on the skin without collapsing after being inserted into the subcutaneous layer. In another exemplary embodiment, a plurality ofpartitions16 may be formed in thehollow portion12cto reinforce the recoiling force, as shown inFIG. 3.
• Thepartitions16 may be formed to completely or incompletely divide thehollow portion12cof themain body12. Thepartitions16 may be made of the same material as themain body12.
• In another exemplary embodiment, a spiralelastic support17 may be formed in thehollow portion12cto reinforce the recoiling force, as shown inFIG. 4. In another exemplary embodiment, the spiralelastic support17 may be formed outside themain body12 so as to surround the outer surface of themain body12. The spiralelastic support17 may be made of the same material as themain body12. In addition to reinforcing the recoiling force, the spiralelastic support17 may allow easier insertion into a curved part since, when the filler for removing wrinkles according to the present disclosure is inserted into the subcutaneous layer with a curved shape, the spiral structure can become narrower or wider depending on the curvature.
• In another exemplary embodiment of the present disclosure, afiller10 for removing wrinkles as shown inFIG. 6 may be provided. In thefiller10 for removing wrinkles, a plurality ofmain bodies12 are disposed in a row such that individualhollow portions12care adjacent to each other, and aconnector12dpenetrating thehollow portions12cformed in themain bodies12 in a lengthwise direction is further provided so that the plurality ofmain bodies12 are used as a series of fillers for removing wrinkles. According to this embodiment, thefiller10 for removing wrinkles can be more easily inserted into the subcutaneous layer with a curved shape, as shown inFIG. 7.
• In another exemplary embodiment of the present disclosure, afiller10 for removing wrinkles whereinelastic cogs12eare formed on the outer surface of amain body12 by partially cutting the surface may be provided, as shown inFIG. 8. In thefiller10 for removing wrinkles, the plurality ofelastic cogs12eprojecting in one direction are further formed on the outer surface of themain body12 along the lengthwise direction of themain body12. According to this embodiment, theelastic cogs12eremain folded (the elastic cogs are accommodated in grooves partially cut on the outer surface) in the subcutaneous layer while thefiller10 for removing wrinkles is being inserted into the subcutaneous layer, as shown inFIG. 9. Then, after the insertion of thefiller10 for removing wrinkles into the subcutaneous layer is completed, theelastic cogs12erestore to the original state of projecting in one direction from the main body12 (seeFIG. 8) owing to elasticity, as shown inFIG. 10. The restoredelastic cogs12eare caught by tissues and prevent thefiller10 for removing wrinkles from retreating in the subcutaneous layer, thereby ensuring fixation to the subcutaneous layer.
• In thefiller10 for removing wrinkles according to the present disclosure, growth factors for facilitating the formation of fibrous tissue may be coated on the outer surface or inner surface of themain body12 or included in themain body12. The growth factor may be angiogenesis factor, platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), transforming growth factor-a (TGF-α), transforming growth factor-β (TGF-β), epidermal growth factor (EGF), connective tissue growth factor (CTGF), vascular endothelial growth factor (VEGF), etc., but is not limited thereto.
• The filler for removing wrinkles according to the present disclosure may be easily inserted by threading one end thereof on a needle for cosmetic surgery or by connecting to the tip of the needle according to a commonly employed method. Hereinafter, a method for removing wrinkles using the filler for removing wrinkles according to the present disclosure will be described in detail referring toFIG. 5.
• A wrinkled area to which the filler is to be inserted is marked and an anesthetic ointment is applied thereon. Then, a needle is inserted from one end of the marked area into the subcutaneous layer, particularly between the subcutaneous fat layer and the dermis or into the fat layer, and pulled at the other end, such that the filler for removing wrinkles spans over the marked area. Then, the portion coming out of the skin S is removed by cutting. Subsequently, blood, red blood cells, white blood cells, platelets, fibroblasts, myofibroblasts, etc. are filled in ahollow portion12cof thefiller10 for removing wrinkles inserted into the subcutaneous layer. The amount of the fibroblasts reaches maximum 3-5 days after the insertion, and that of the myofibroblasts reaches maximum at 5-15 days. Thereafter, collagen is synthesized by the fibroblasts, resulting in fibrous tissue T. The fibrous tissue T provides a wrinkle-correcting effect.
• While the exemplary embodiments have been shown and described, it will be understood by those skilled in the art that various changes in form and details may be made thereto without departing from the spirit and scope of this disclosure as defined by the appended claims.

Claims (15)

1. A filler for removing wrinkles, comprising:

a thin and long tubular main body provided so as to penetrate the subcutaneous layer; and

through-holes provided so as to guide tissue cells surrounding the main body into the main body to form fibrous tissue, wherein the through-holes are formed to communicate with a hollow portion formed in the main body in a lengthwise direction from the outer surface of the main body.

2. The filler for removing wrinkles according toclaim 1, wherein the main body is formed integrally and has a circular transection.

3. The filler for removing wrinkles according toclaim 2, wherein the main body has a diameter of 0.6-1.0 mm, and the hollow portion has a diameter of 0.5-0.7 mm.

4. The filler for removing wrinkles according toclaim 2, wherein the through-holes have a diameter or a circle-equivalent diameter of 40-500 μm.

5. The filler for removing wrinkles according toclaim 1, wherein the main body is formed by spirally winding a plurality of strip-shaped parts so as to cross each other, such that the hollow portion is provided in the parts in a lengthwise direction, and the through-holes communicating with the hollow portion from the outer surface of the main body are provided by the gaps between the parts.

6. The filler for removing wrinkles according toclaim 1, wherein the main body is made of an elastic material.

7. The filler for removing wrinkles according toclaim 1, wherein the main body is made of a biodegradable polymer selected from a group consisting of hyaluronic acid (HA), polylactic acid (PLA), polyglyco-lactic acid (PGLA) and polydioxanone (PDS).

8. The filler for removing wrinkles according toclaim 1, wherein the main body is made of a non-biodegradable polymer selected from a group consisting of nylon, silicone and Teflon.

9. The filler for removing wrinkles according toclaim 1, wherein the main body has a double-layer structure comprising an inner sheath and an outer sheath made of different materials having different physical properties.

10. The filler for removing wrinkles according toclaim 1, wherein a plurality of partitions are further formed in the hollow portion.

11. The filler for removing wrinkles according toclaim 1, wherein a spiral elastic support is further formed in the hollow portion.

12. The filler for removing wrinkles according toclaim 1, wherein a spiral elastic support is further provided outside the main body so as to surround the outer surface of the main body.

13. The filler for removing wrinkles according toclaim 1, wherein a plurality of the main bodies are disposed in a row such that the hollow portions are adjacent to each other, and a connector penetrating the hollow portions formed in the main bodies in a lengthwise direction is further provided so that the plurality of main bodies are used as a series of fillers for removing wrinkles

14. The filler for removing wrinkles according toclaim 1, wherein a plurality of elastic projections projecting in one direction are further formed on the outer surface of the main body along the lengthwise direction of the main body.

15. The filler for removing wrinkles according toclaim 1, wherein growth factors for facilitating the formation of fibrous tissue are coated on the outer surface or inner surface of the main body or included in the main body.

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