US20040116831A1 - Distal protection guidewire with nitinol core - Google Patents
Distal protection guidewire with nitinol coreDownload PDFInfo
- Publication number
- US20040116831A1 US20040116831A1US10/318,907US31890702AUS2004116831A1US 20040116831 A1US20040116831 A1US 20040116831A1US 31890702 AUS31890702 AUS 31890702AUS 2004116831 A1US2004116831 A1US 2004116831A1
- Authority
- US
- United States
- Prior art keywords
- guidewire
- section
- distal
- proximal
- distal section
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/011—Instruments for their placement or removal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/013—Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2/013—Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
- A61F2002/015—Stop means therefor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/01—Filters implantable into blood vessels
- A61F2002/018—Filters implantable into blood vessels made from tubes or sheets of material, e.g. by etching or laser-cutting
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0006—Rounded shapes, e.g. with rounded corners circular
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0073—Quadric-shaped
- A61F2230/008—Quadric-shaped paraboloidal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09058—Basic structures of guide wires
- A61M2025/09075—Basic structures of guide wires having a core without a coil possibly combined with a sheath
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09133—Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
- A61M2025/09141—Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque made of shape memory alloys which take a particular shape at a certain temperature
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/0915—Guide wires having features for changing the stiffness
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09175—Guide wires having specific characteristics at the distal tip
- A61M2025/09183—Guide wires having specific characteristics at the distal tip having tools at the distal tip
Definitions
- the present inventionrelates generally to the field of intravascular guidewires. More specifically, the present invention pertains to guidewires having super-elastic properties.
- Guidewiresare frequently used to advance intravascular devices such as stent delivery catheters, angioplasty catheters, and atherectomy catheters within a patient's vasculature.
- intravascular devicessuch as stent delivery catheters, angioplasty catheters, and atherectomy catheters within a patient's vasculature.
- Such devicesgenerally include a stiff proximal section to facilitate pushability and torqueability, and a flexible distal section for improved trackability.
- the distal section of the guidewiremay have a reduced profile capable of placement beyond a lesion or other stenosis within the body.
- One important aspect of guidewire designsis the ability of the distal section to undergo significant bending within the body without permanently deforming the guidewire. Kinking results when the stress within the guidewire exceeds the elastic limit of the material, causing the material to plastically deform. As a result, a residual strain is imparted to the guidewire preventing it from fully recovering to its original shape. In certain circumstances, the inability of the guidewire to return to its original shape may diminish the performance and durability characteristics of the guidewire.
- a guidewirecomprises a proximal section formed of a first material, and a distal section formed of a second material different from the first material.
- the proximal section of the guidewiremay be formed of a relatively stiff, inelastic material, whereas the distal section may be formed of a relatively flexible, elastic material.
- the distal sectionmay be formed of a super-elastic material such as nickel-titanium alloy.
- a coupling membermay be attached to the guidewire adjacent a transition section, securing the proximal and distal sections together.
- FIG. 1is a plan view of an intravascular guidewire in accordance with an exemplary embodiment of the present invention, showing an embolic protection filter advanced along the guidewire;
- FIG. 2is a plan view of an intravascular guidewire in accordance with another exemplary embodiment of the present invention.
- FIG. 1is a plan view of an intravascular guidewire in accordance with an exemplary embodiment of the present invention.
- Guidewire 10includes a proximal section 12 , a distal section 14 , and a transition section 16 securing the proximal section 12 to the distal section 14 .
- Guidewire 10is configured to support one or more intravascular devices thereon, such as the embolic protection filter 46 illustrated in FIG. 1.
- the proximal section 12 of guidewire 10may be formed of a relatively stiff, inelastic material to enhance the pushability and torqueability characteristics of the guidewire, and to support the weight of various intravascular devices (e.g. balloon catheters, stent delivery catheters, etc.) thereon.
- Proximal section 12may be formed of a metal such as type 304 V stainless steel or platinum.
- the distal section 14 of guidewire 10may be formed of a relatively flexible, elastic material configured to impart flexibility to the guidewire for enhanced tracking through the tortuous vasculature.
- the distal section 14may be formed from a material having different mechanical properties than the proximal section 12 of the guidewire 10 .
- the distal section 14may be formed from a material having a lower modulus of elasticity than the proximal section 12 , thereby imparting greater flexibility to the distal section 14 .
- the distal section 14may comprise a super-elastic and/or linear-elastic material such as nickel-titanium alloy (Nitinol).
- Nickel-titanium alloyexhibits pseudo-elastic capabilities at body temperature (37° C.), allowing it to undergo substantial bending with relatively little residual strain. Unlike more commonly used materials such as stainless steel, the use of super-elastic materials such as Nitinol allows the distal section 14 to bend significantly without permanently (i.e. plastically) deforming.
- Guidewire 10further includes a transition section 16 forming a joint between the proximal and distal sections 12 , 14 .
- the distal end 20 of the proximal section 12may be coupled to the proximal end 22 of the distal section 14 , forming a butt joint therebetween.
- the proximal and distal sections 12 , 14 of the guidewire 10may be bonded together by adhesive, welding (e.g. resistance, laser, ultrasonic), soldering, brazing, or any other suitable bonding technique.
- guidewire 10may include a coupling member 24 further securing the proximal section 12 to the distal section 14 .
- the coupling member 24may comprise a tubular member or wire coil having an inner diameter configured to receive the distal end 20 of the proximal section 12 and the proximal end 22 of the distal section 14 .
- the coupling member 24may be formed from a metal or metal alloy, including stainless steel, nickel-titanium alloy, nickel-chromium alloy, nickel-chromium-iron alloy, nickel-chromium-molybdenum, cobalt alloy, or nickel.
- a nickel-chromium-molybdenum based alloysuch as INCONEL 625, ALLOY C276 or ALLOY B2 may be used.
- INCONEL 625is commercially available from the California Fine Wire Company of Grover Beach, Calif.
- ALLOY C276 and B2are commercially available from the Fort Wayne Metals Research Products Corporation of Fort Wayne, Ind.
- the coupling member 24may comprise a polymeric material that can be heat shrunk adjacent the ends 20 , 22 of the proximal and distal sections 12 , 14 .
- a tubular segment formed of polytetraflouroethylene (PTFE)can be placed adjacent the ends 20 , 22 of the two sections 12 , 14 and heated to a sufficient temperature, causing the material to flow onto the ends 20 , 22 .
- the coupling member 24may include a solder material that can be reflowed adjacent the ends 20 , 22 of the proximal and distal sections 12 , 14 .
- the ends 20 , 22 of the proximal and distal sections 12 , 14may be tapered or reduced in diameter such that the profile of the guidewire 10 at the transition section 16 is substantially similar to the profile of the proximal and distal sections 12 , 14 immediately adjacent the transition section 16 .
- the ends 20 , 22 of the proximal and distal sections 12 , 14may include a necked-down portion 26 reducing the outer diameter of the sections 12 , 14 at the transition section 16 .
- the distal section 14may also include a shaping ribbon 28 .
- the shaping ribbon 28connects the distal end 30 of the distal section 14 to a coil tip 34 disposed at the distal end 32 of the guidewire 10 .
- the shaping ribbon 28may be formed of metal (e.g. type 304V stainless steel), a polymer, or any other suitable material.
- Coil tip 34is generally circular in shape, and includes a proximal portion 36 forming a rearwardly facing shoulder, and a distal portion 38 .
- the coil tip 34may be substantially round, and may include a hydrophilic coating to reduce tissue damage within the body.
- Guidewire 10may also include a wire coil 40 disposed at least in part about the distal section 14 .
- the wire coil 40may be attached at a proximal end 42 to the distal section 14 , and at a distal end 44 to the proximal portion 36 of coil tip 34 .
- the wire coil 40may be formed from a single, continuous strand of wire helically disposed about the distal section 14 .
- the wire coil 40may comprise a radiopaque material such as gold, platinum, or tantalum, allowing the operator to fluoroscopically judge the location of the guidewire 10 within the body.
- An intravascular devicesuch as the embolic protection filter 46 depicted in FIG. 1 may be placed on the guidewire 10 .
- the embolic protection filter 46may include a tubular base member 48 , which allows the filter 46 to slide and rotate about the guidewire 10 .
- the guidewire 10may be percutaneously inserted into a blood vessel, and advanced to a desired location within the body (e.g. a coronary artery). Once positioned, the embolic protection filter 46 can then be advanced over the guidewire 10 via a delivery catheter, and placed at a location downstream a lesion or other stenosis within the vessel.
- An intravascular devicesuch as an angioplasty balloon can then be advanced along the guidewire 10 to a location upstream of the embolic protection filter 46 to perform a therapeutic procedure such as percutaneous transluminal coronary angioplasty.
- a stentmay also be advanced along the guidewire 10 and deployed within the body, if desired.
- the embolic protection filter 46may be fixedly secured to the distal section 14 of the guidewire 10 prior to insertion within the patient.
- the guidewire 10 and attached embolic protection filterare both loaded into the delivery catheter prior to being inserted into the body.
- the guidewire 10 and attached filterare simultaneously inserted into the body, and then advanced to the site of the lesion. Once positioned distal the lesion, the guidewire can then be used to advance other intravascular devices to the site.
- embolic protection filter 46may include a filter mesh or membrane 50 coupled to a proximal support hoop 52 .
- the proximal support hoop 52forms a mouth or opening on the embolic protection filter 46 , and is biased to radially expand within the vessel when removed from the delivery catheter.
- the filter mesh or membrane 50may include several openings or pores 54 configured to filter embolic debris while permitting the perfusion of blood through the blood vessel.
- a tether line 56connects the embolic protection filter 46 to the tubular base member 48 .
- Embolic protection filter 46may further include a nose cone 58 .
- Nose cone 58is formed from an enlarged diameter distal portion of the tubular base member 48 .
- the nose cone 58is tapered distally to provide a relatively uniform profile transition between the proximal end 42 of the wire coil 40 and the embolic protection filter 46 .
- a reduced inner diameter portion 60 on the distal end 62 of the nose cone 58is adapted to slide over the proximal end 42 of the wire coil 40 .
- the proximal end 42 of the wire coil 40acts as a distal stop, preventing the embolic protection filter 46 from being advanced beyond the distal end 32 of the guidewire 10 .
- FIG. 2is a plan view of an intravascular guidewire in accordance with another exemplary embodiment of the present invention.
- Guidewire 110includes a proximal section 112 , a distal section 114 , and a transition section 116 .
- guidewire 110is configured to support one or more intravascular devices thereon.
- the proximal section 112 of guidewire 110may comprise a relatively stiff, inelastic material (e.g. type 304V stainless steel), whereas the distal section 114 may comprise a relatively flexible, super-elastic material such as nickel-titanium alloy.
- the distal end 120 of the proximal section 112may include a notch configured to align with a correspondingly dimensioned notch on the proximal end 122 of the distal section 114 . Together, the notches form a lap joint 162 between the proximal and distal sections 112 , 114 .
- a coupling member 124may also be placed adjacent the ends 120 , 122 of the proximal and distal sections 112 , 114 at the transitional section 116 .
- the ends 120 , 122 of the proximal and distal sections 112 , 114may be tapered or reduced in diameter such that the profile of the guidewire 110 at the transition section 116 is substantially similar to the profile of the proximal and distal sections 112 , 114 immediately adjacent the transition section 116 .
- a wire coil 140may be placed about a portion of the distal section 114 .
- Wire coil 140has a proximal end 142 and a distal end 144 .
- the proximal end 142 of wire coil 140may be attached to a shoulder 164 located on the distal section 114 of the guidewire 110 .
- the distal end 144 of wire coil 140in turn, may be attached to the proximal portion 136 of the coil tip 134 .
- a shaping ribbon 128 connecting the distal end 130 of the distal section 114 to the proximal portion 136 of the coil tip 134may also be used, if desired.
- Guidewire 110further includes a distal stop 166 disposed about a portion of the distal section 114 .
- Distal stop 166comprises an object having an outer diameter slightly larger than the inner diameter of the intravascular device. In use, the distal stop 166 prevents movement of the intravascular device beyond the distal end 132 of the guidewire 110 .
- Attachment of the distal stop 166 to the guidewire 110may be accomplished by any number of suitable attachment means, including crimping, soldering, brazing, welding, adhesion or any combination thereof.
- the distal stop 166may be formed from any number of suitable materials, such as stainless steel or nickel-titanium alloy.
- the distal stop 166may be formed by heat bonding a polymeric object about the distal section 114 .
- FIGS. 1 - 2depict a guidewire 10 , 110 having a solid core (i.e. solid cross-section), it should be understood that other configurations are possible without deviating from the scope of the invention.
- the proximal and distal sectionsmay have a hollow cross-sectional area, forming a guide catheter or the like.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Materials For Medical Uses (AREA)
Abstract
Description
- The present invention relates generally to the field of intravascular guidewires. More specifically, the present invention pertains to guidewires having super-elastic properties.[0001]
- Guidewires are frequently used to advance intravascular devices such as stent delivery catheters, angioplasty catheters, and atherectomy catheters within a patient's vasculature. Such devices generally include a stiff proximal section to facilitate pushability and torqueability, and a flexible distal section for improved trackability. In some cases, the distal section of the guidewire may have a reduced profile capable of placement beyond a lesion or other stenosis within the body.[0002]
- One important aspect of guidewire designs is the ability of the distal section to undergo significant bending within the body without permanently deforming the guidewire. Kinking results when the stress within the guidewire exceeds the elastic limit of the material, causing the material to plastically deform. As a result, a residual strain is imparted to the guidewire preventing it from fully recovering to its original shape. In certain circumstances, the inability of the guidewire to return to its original shape may diminish the performance and durability characteristics of the guidewire.[0003]
- The present invention relates generally to guidewires having super-elastic properties. In an exemplary embodiment of the present invention, a guidewire comprises a proximal section formed of a first material, and a distal section formed of a second material different from the first material. The proximal section of the guidewire may be formed of a relatively stiff, inelastic material, whereas the distal section may be formed of a relatively flexible, elastic material. In some embodiments, the distal section may be formed of a super-elastic material such as nickel-titanium alloy. A coupling member may be attached to the guidewire adjacent a transition section, securing the proximal and distal sections together.[0004]
- FIG. 1 is a plan view of an intravascular guidewire in accordance with an exemplary embodiment of the present invention, showing an embolic protection filter advanced along the guidewire; and[0005]
- FIG. 2 is a plan view of an intravascular guidewire in accordance with another exemplary embodiment of the present invention.[0006]
- The following description should be read with reference to the drawings, in which like elements in different drawings are numbered in like fashion. The drawings, which are not necessarily to scale, depict selected embodiments and are not intended to limit the scope of the invention. Although examples of construction, dimensions, and materials are illustrated for the various elements, those skilled in the art will recognize that many of the examples provided have suitable alternatives that may be utilized.[0007]
- FIG. 1 is a plan view of an intravascular guidewire in accordance with an exemplary embodiment of the present invention.[0008]
Guidewire 10 includes aproximal section 12, a distal section14, and atransition section 16 securing theproximal section 12 to the distal section14. Guidewire10 is configured to support one or more intravascular devices thereon, such as theembolic protection filter 46 illustrated in FIG. 1. - The[0009]
proximal section 12 ofguidewire 10 may be formed of a relatively stiff, inelastic material to enhance the pushability and torqueability characteristics of the guidewire, and to support the weight of various intravascular devices (e.g. balloon catheters, stent delivery catheters, etc.) thereon.Proximal section 12 may be formed of a metal such as type304V stainless steel or platinum. - The distal section[0010]14 of
guidewire 10 may be formed of a relatively flexible, elastic material configured to impart flexibility to the guidewire for enhanced tracking through the tortuous vasculature. The distal section14 may be formed from a material having different mechanical properties than theproximal section 12 of theguidewire 10. For example, the distal section14 may be formed from a material having a lower modulus of elasticity than theproximal section 12, thereby imparting greater flexibility to the distal section14. In one exemplary embodiment, the distal section14 may comprise a super-elastic and/or linear-elastic material such as nickel-titanium alloy (Nitinol). Nickel-titanium alloy exhibits pseudo-elastic capabilities at body temperature (37° C.), allowing it to undergo substantial bending with relatively little residual strain. Unlike more commonly used materials such as stainless steel, the use of super-elastic materials such as Nitinol allows the distal section14 to bend significantly without permanently (i.e. plastically) deforming. - [0011]
Guidewire 10 further includes atransition section 16 forming a joint between the proximal anddistal sections 12,14. As shown in FIG. 1, for example, thedistal end 20 of theproximal section 12 may be coupled to theproximal end 22 of the distal section14, forming a butt joint therebetween. The proximal anddistal sections 12,14 of theguidewire 10 may be bonded together by adhesive, welding (e.g. resistance, laser, ultrasonic), soldering, brazing, or any other suitable bonding technique. - In certain embodiments,[0012]
guidewire 10 may include acoupling member 24 further securing theproximal section 12 to the distal section14. Thecoupling member 24 may comprise a tubular member or wire coil having an inner diameter configured to receive thedistal end 20 of theproximal section 12 and theproximal end 22 of the distal section14. Thecoupling member 24 may be formed from a metal or metal alloy, including stainless steel, nickel-titanium alloy, nickel-chromium alloy, nickel-chromium-iron alloy, nickel-chromium-molybdenum, cobalt alloy, or nickel. For example, in bonding a stainless steelproximal section 12 to a nickel-titanium distal section14, a nickel-chromium-molybdenum based alloy such as INCONEL 625, ALLOY C276 or ALLOY B2 may be used. INCONEL 625 is commercially available from the California Fine Wire Company of Grover Beach, Calif. ALLOY C276 and B2 are commercially available from the Fort Wayne Metals Research Products Corporation of Fort Wayne, Ind. - In an alternative embodiment, the[0013]
coupling member 24 may comprise a polymeric material that can be heat shrunk adjacent theends distal sections 12,14. For example, a tubular segment formed of polytetraflouroethylene (PTFE) can be placed adjacent theends sections 12,14 and heated to a sufficient temperature, causing the material to flow onto theends coupling member 24 may include a solder material that can be reflowed adjacent theends distal sections 12,14. - In those embodiments utilizing a[0014]
coupling member 24, theends distal sections 12,14 may be tapered or reduced in diameter such that the profile of theguidewire 10 at thetransition section 16 is substantially similar to the profile of the proximal anddistal sections 12,14 immediately adjacent thetransition section 16. As shown in FIG. 1, for example, theends distal sections 12,14 may include a necked-downportion 26 reducing the outer diameter of thesections 12,14 at thetransition section 16. - The distal section[0015]14 may also include a shaping
ribbon 28. Theshaping ribbon 28 connects thedistal end 30 of the distal section14 to acoil tip 34 disposed at thedistal end 32 of theguidewire 10. The shapingribbon 28 may be formed of metal (e.g. type 304V stainless steel), a polymer, or any other suitable material. - [0016]
Coil tip 34 is generally circular in shape, and includes aproximal portion 36 forming a rearwardly facing shoulder, and adistal portion 38. Thecoil tip 34 may be substantially round, and may include a hydrophilic coating to reduce tissue damage within the body. - Guidewire[0017]10 may also include a
wire coil 40 disposed at least in part about the distal section14. Thewire coil 40 may be attached at aproximal end 42 to the distal section14, and at adistal end 44 to theproximal portion 36 ofcoil tip 34. Thewire coil 40 may be formed from a single, continuous strand of wire helically disposed about the distal section14. In certain embodiments, thewire coil 40 may comprise a radiopaque material such as gold, platinum, or tantalum, allowing the operator to fluoroscopically judge the location of theguidewire 10 within the body. - An intravascular device such as the[0018]
embolic protection filter 46 depicted in FIG. 1 may be placed on theguidewire 10. Theembolic protection filter 46 may include atubular base member 48, which allows thefilter 46 to slide and rotate about theguidewire 10. In use, theguidewire 10 may be percutaneously inserted into a blood vessel, and advanced to a desired location within the body (e.g. a coronary artery). Once positioned, theembolic protection filter 46 can then be advanced over theguidewire 10 via a delivery catheter, and placed at a location downstream a lesion or other stenosis within the vessel. An intravascular device such as an angioplasty balloon can then be advanced along theguidewire 10 to a location upstream of theembolic protection filter 46 to perform a therapeutic procedure such as percutaneous transluminal coronary angioplasty. A stent may also be advanced along theguidewire 10 and deployed within the body, if desired. - In an alternative embodiment (not shown), the[0019]
embolic protection filter 46 may be fixedly secured to the distal section14 of theguidewire 10 prior to insertion within the patient. In a fixed configuration, theguidewire 10 and attached embolic protection filter are both loaded into the delivery catheter prior to being inserted into the body. Theguidewire 10 and attached filter are simultaneously inserted into the body, and then advanced to the site of the lesion. Once positioned distal the lesion, the guidewire can then be used to advance other intravascular devices to the site. - To collect embolic debris dislodged during the therapeutic procedure,[0020]
embolic protection filter 46 may include a filter mesh ormembrane 50 coupled to aproximal support hoop 52. Theproximal support hoop 52 forms a mouth or opening on theembolic protection filter 46, and is biased to radially expand within the vessel when removed from the delivery catheter. The filter mesh ormembrane 50 may include several openings orpores 54 configured to filter embolic debris while permitting the perfusion of blood through the blood vessel. Atether line 56 connects theembolic protection filter 46 to thetubular base member 48. - [0021]
Embolic protection filter 46 may further include anose cone 58.Nose cone 58 is formed from an enlarged diameter distal portion of thetubular base member 48. Thenose cone 58 is tapered distally to provide a relatively uniform profile transition between theproximal end 42 of thewire coil 40 and theembolic protection filter 46. A reducedinner diameter portion 60 on the distal end62 of thenose cone 58 is adapted to slide over theproximal end 42 of thewire coil 40. In use, theproximal end 42 of thewire coil 40 acts as a distal stop, preventing theembolic protection filter 46 from being advanced beyond thedistal end 32 of theguidewire 10. - FIG. 2 is a plan view of an intravascular guidewire in accordance with another exemplary embodiment of the present invention.[0022]
Guidewire 110 includes aproximal section 112, adistal section 114, and atransition section 116. As with the embodiment described above with respect to FIG. 1,guidewire 110 is configured to support one or more intravascular devices thereon. - The[0023]
proximal section 112 ofguidewire 110 may comprise a relatively stiff, inelastic material (e.g. type 304V stainless steel), whereas thedistal section 114 may comprise a relatively flexible, super-elastic material such as nickel-titanium alloy. Thedistal end 120 of theproximal section 112 may include a notch configured to align with a correspondingly dimensioned notch on theproximal end 122 of thedistal section 114. Together, the notches form a lap joint162 between the proximal anddistal sections - A[0024]
coupling member 124 may also be placed adjacent theends distal sections transitional section 116. In those embodiments utilizing acoupling member 124, theends distal sections guidewire 110 at thetransition section 116 is substantially similar to the profile of the proximal anddistal sections transition section 116. - A[0025]
wire coil 140 may be placed about a portion of thedistal section 114.Wire coil 140 has aproximal end 142 and adistal end 144. Theproximal end 142 ofwire coil 140 may be attached to ashoulder 164 located on thedistal section 114 of theguidewire 110. Thedistal end 144 ofwire coil 140, in turn, may be attached to theproximal portion 136 of thecoil tip 134. A shapingribbon 128 connecting thedistal end 130 of thedistal section 114 to theproximal portion 136 of thecoil tip 134 may also be used, if desired. - [0026]
Guidewire 110 further includes adistal stop 166 disposed about a portion of thedistal section 114.Distal stop 166 comprises an object having an outer diameter slightly larger than the inner diameter of the intravascular device. In use, thedistal stop 166 prevents movement of the intravascular device beyond the distal end132 of theguidewire 110. - Attachment of the[0027]
distal stop 166 to theguidewire 110 may be accomplished by any number of suitable attachment means, including crimping, soldering, brazing, welding, adhesion or any combination thereof. Furthermore, thedistal stop 166 may be formed from any number of suitable materials, such as stainless steel or nickel-titanium alloy. In one implementation, thedistal stop 166 may be formed by heat bonding a polymeric object about thedistal section 114. - Although the exemplary embodiments illustrated in FIGS.[0028]1-2 depict a
guidewire - Having thus described the several embodiments of the present invention, those of skill in the art will readily appreciate that other embodiments may be made and used which fall within the scope of the claims attached hereto. Numerous advantages of the invention covered by this document have been set forth in the foregoing description. It will be understood that this disclosure is, in many respects, only illustrative. Changes may be made in details, particularly in matters of shape, size and arrangement of parts without exceeding the scope of the invention.[0029]
Claims (37)
1. A guidewire, comprising:
an elongate shaft including a proximal section, a distal section, and a transition section, the proximal section comprising a first material, the distal section comprising a second material different from the first material;
a coupling member attached adjacent to the transition section, said coupling member configured to secure the proximal section to the distal section; and
an embolic protection filter disposed on the shaft.
2. The guidewire ofclaim 1 , wherein the proximal section is comprised of stainless steel.
3. The guidewire ofclaim 1 , wherein the distal section is comprised of a super-elastic material.
4. The guidewire ofclaim 1 , wherein the distal section is comprised of a linear-elastic material.
5. The guidewire ofclaim 1 , wherein the distal section is comprised of nickel-titanium alloy.
6. The guidewire ofclaim 1 , wherein the transition section forms a joint between the proximal and distal sections.
7. The guidewire ofclaim 6 , wherein said joint is a butt joint.
8. The guidewire ofclaim 6 , wherein said joint is a lap joint.
9. The guidewire ofclaim 1 , wherein the transition section includes a necked-down portion.
10. The guidewire ofclaim 1 , wherein the coupling member comprises a tubular member.
11. The guidewire ofclaim 1 , wherein the coupling member comprises a nickel-chromium-molybdenum alloy tube.
12. The guidewire ofclaim 1 , wherein the coupling member comprises a polymeric member heat shrunk adjacent to the transition section.
13. The guidewire ofclaim 1 , further comprising a wire coil disposed about a portion of said distal section.
14. The guidewire ofclaim 13 , wherein said wire coil is formed from a single continuous strand of wire helically disposed about a portion of said distal section.
15. The guidewire ofclaim 13 , wherein said wire coil comprises a radiopaque material.
16. The guidewire ofclaim 1 , further comprising a coil tip.
17. The guidewire ofclaim 16 , wherein said coil tip includes a hydrophilic coating.
18. The guidewire ofclaim 1 , further comprising a safety ribbon.
19. The guidewire ofclaim 1 , further comprising a distal stop disposed about a portion of said distal section.
20. A guidewire, comprising:
an elongate shaft including a proximal section formed of a relatively stiff, elastic material, a distal section formed of a relatively flexible, elastic material, and a transition section forming a joint between the proximal and distal sections;
a coupling member attached adjacent to the transition section; and
an embolic protection filter disposed on the shaft.
21. The guidewire ofclaim 20 , wherein the proximal section is comprised of stainless steel.
22. The guidewire ofclaim 20 , wherein the distal section is comprised of a super-elastic material.
23. The guidewire ofclaim 20 , wherein the distal section is comprised of a linear-elastic material.
24. The guidewire ofclaim 20 , wherein the distal section is comprised of nickel-titanium alloy.
25. The guidewire ofclaim 20 , wherein said joint is a butt joint.
26. The guidewire ofclaim 20 , wherein said joint is a lap joint.
27. The guidewire ofclaim 20 , wherein the transition section includes a necked-down portion.
28. The guidewire ofclaim 20 , wherein the coupling member comprises a tubular member.
29. The guidewire ofclaim 20 , wherein the coupling member comprises a nickel-chromium-molybdenum alloy tube.
30. The guidewire ofclaim 20 , wherein the coupling member comprises a polymeric member heat shrunk adjacent to the transition section.
31. The guidewire ofclaim 20 , further comprising a wire coil disposed about a portion of said distal section.
32. The guidewire ofclaim 31 , wherein said wire coil is formed from a single continuous strand of wire helically disposed about a portion of said distal section.
33. The guidewire ofclaim 31 , wherein said wire coil comprises a radiopaque material.
34. The guidewire ofclaim 20 , further comprising a coil tip.
35. The guidewire ofclaim 34 , wherein said coil tip includes a hydrophilic coating.
36. The guidewire ofclaim 20 , further comprising a safety ribbon.
37. The guidewire ofclaim 20 , further comprising a distal stop disposed about a portion of said distal section.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/318,907US20040116831A1 (en) | 2002-12-13 | 2002-12-13 | Distal protection guidewire with nitinol core |
| EP03813424AEP1578469A2 (en) | 2002-12-13 | 2003-12-11 | Distal protection guidewire with nizinol core |
| AU2003297015AAU2003297015A1 (en) | 2002-12-13 | 2003-12-11 | Distal protection guidewire with nizinol core |
| JP2004560843AJP2006509591A (en) | 2002-12-13 | 2003-12-11 | Tip protector type guide wire with nitinol core |
| CA2509676ACA2509676C (en) | 2002-12-13 | 2003-12-11 | Distal protection guidewire with nitinol core |
| PCT/US2003/039689WO2004054652A2 (en) | 2002-12-13 | 2003-12-11 | Distal protection guidewire with nizinol core |
| US11/608,619US8083689B2 (en) | 2002-12-13 | 2006-12-08 | Distal protection guidewire with nitinol core |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/318,907US20040116831A1 (en) | 2002-12-13 | 2002-12-13 | Distal protection guidewire with nitinol core |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US11/608,619ContinuationUS8083689B2 (en) | 2002-12-13 | 2006-12-08 | Distal protection guidewire with nitinol core |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US20040116831A1true US20040116831A1 (en) | 2004-06-17 |
Family
ID=32506500
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US10/318,907AbandonedUS20040116831A1 (en) | 2002-12-13 | 2002-12-13 | Distal protection guidewire with nitinol core |
| US11/608,619Expired - Fee RelatedUS8083689B2 (en) | 2002-12-13 | 2006-12-08 | Distal protection guidewire with nitinol core |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US11/608,619Expired - Fee RelatedUS8083689B2 (en) | 2002-12-13 | 2006-12-08 | Distal protection guidewire with nitinol core |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20040116831A1 (en) |
| EP (1) | EP1578469A2 (en) |
| JP (1) | JP2006509591A (en) |
| AU (1) | AU2003297015A1 (en) |
| CA (1) | CA2509676C (en) |
| WO (1) | WO2004054652A2 (en) |
Cited By (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060006649A1 (en)* | 2004-06-25 | 2006-01-12 | Galdonik Jason A | Medical device having mechanically interlocked segments |
| US20060047222A1 (en)* | 2003-08-27 | 2006-03-02 | Heuser Richard R | Catheter guidewire system using concentric wires |
| US20060229660A1 (en)* | 2005-03-15 | 2006-10-12 | Dharmendra Pal | Embolic protection device |
| US20060276805A1 (en)* | 2005-05-03 | 2006-12-07 | Yu Chun H | Vessel recanalizer |
| US20070123805A1 (en)* | 2003-02-26 | 2007-05-31 | Boston Scientific Scimed, Inc. | Elongated intracorporal medical device |
| US20070203572A1 (en)* | 2006-01-25 | 2007-08-30 | Heuser Richard R | Catheter system with stent apparatus for connecting adjacent blood vessels |
| US20070219579A1 (en)* | 2006-03-20 | 2007-09-20 | Cook Incorporated | Distal protection device |
| US20070287955A1 (en)* | 2002-07-25 | 2007-12-13 | Boston Scientific Scimed, Inc. | Tubular member having tapered transition for use in a medical device |
| US7374567B2 (en) | 2006-01-25 | 2008-05-20 | Heuser Richard R | Catheter system for connecting adjacent blood vessels |
| US20080177249A1 (en)* | 2007-01-22 | 2008-07-24 | Heuser Richard R | Catheter introducer system |
| US20080188831A1 (en)* | 2007-02-06 | 2008-08-07 | Possis Medical, Inc. | Miniature flexible thrombectomy catheter |
| US20080234813A1 (en)* | 2007-03-20 | 2008-09-25 | Heuser Richard R | Percutaneous Interventional Cardiology System for Treating Valvular Disease |
| US20080289181A1 (en)* | 2007-02-06 | 2008-11-27 | Possis Medical, Inc. | Method of manufacturing a miniature flexible thrombectomy catheter |
| US20090012429A1 (en)* | 2004-08-25 | 2009-01-08 | Heuser Richard R | Catheter guidewire system using concentric wires |
| US7766934B2 (en) | 2005-07-12 | 2010-08-03 | Cook Incorporated | Embolic protection device with an integral basket and bag |
| US7771452B2 (en) | 2005-07-12 | 2010-08-10 | Cook Incorporated | Embolic protection device with a filter bag that disengages from a basket |
| US7824345B2 (en) | 2003-12-22 | 2010-11-02 | Boston Scientific Scimed, Inc. | Medical device with push force limiter |
| US7841994B2 (en) | 2007-11-02 | 2010-11-30 | Boston Scientific Scimed, Inc. | Medical device for crossing an occlusion in a vessel |
| US7846175B2 (en) | 2006-04-03 | 2010-12-07 | Medrad, Inc. | Guidewire and collapsable filter system |
| US7850708B2 (en) | 2005-06-20 | 2010-12-14 | Cook Incorporated | Embolic protection device having a reticulated body with staggered struts |
| US7850623B2 (en) | 2005-10-27 | 2010-12-14 | Boston Scientific Scimed, Inc. | Elongate medical device with continuous reinforcement member |
| US7914492B2 (en) | 2003-01-27 | 2011-03-29 | Heuser Richard R | Catheter introducer system |
| US8062321B2 (en) | 2006-01-25 | 2011-11-22 | Pq Bypass, Inc. | Catheter system for connecting adjacent blood vessels |
| US8105246B2 (en) | 2007-08-03 | 2012-01-31 | Boston Scientific Scimed, Inc. | Elongate medical device having enhanced torque and methods thereof |
| US8109962B2 (en) | 2005-06-20 | 2012-02-07 | Cook Medical Technologies Llc | Retrievable device having a reticulation portion with staggered struts |
| US8137293B2 (en) | 2009-11-17 | 2012-03-20 | Boston Scientific Scimed, Inc. | Guidewires including a porous nickel-titanium alloy |
| US8152831B2 (en) | 2005-11-17 | 2012-04-10 | Cook Medical Technologies Llc | Foam embolic protection device |
| US8182508B2 (en) | 2005-10-04 | 2012-05-22 | Cook Medical Technologies Llc | Embolic protection device |
| US8187298B2 (en) | 2005-08-04 | 2012-05-29 | Cook Medical Technologies Llc | Embolic protection device having inflatable frame |
| US8216269B2 (en) | 2005-11-02 | 2012-07-10 | Cook Medical Technologies Llc | Embolic protection device having reduced profile |
| US8252018B2 (en) | 2007-09-14 | 2012-08-28 | Cook Medical Technologies Llc | Helical embolic protection device |
| US8252017B2 (en) | 2005-10-18 | 2012-08-28 | Cook Medical Technologies Llc | Invertible filter for embolic protection |
| US8376961B2 (en) | 2008-04-07 | 2013-02-19 | Boston Scientific Scimed, Inc. | Micromachined composite guidewire structure with anisotropic bending properties |
| US8377092B2 (en) | 2005-09-16 | 2013-02-19 | Cook Medical Technologies Llc | Embolic protection device |
| US8377035B2 (en) | 2003-01-17 | 2013-02-19 | Boston Scientific Scimed, Inc. | Unbalanced reinforcement members for medical device |
| US8388644B2 (en) | 2008-12-29 | 2013-03-05 | Cook Medical Technologies Llc | Embolic protection device and method of use |
| US8409114B2 (en) | 2007-08-02 | 2013-04-02 | Boston Scientific Scimed, Inc. | Composite elongate medical device including distal tubular member |
| US8419748B2 (en) | 2007-09-14 | 2013-04-16 | Cook Medical Technologies Llc | Helical thrombus removal device |
| US8449526B2 (en) | 2001-07-05 | 2013-05-28 | Boston Scientific Scimed, Inc. | Torqueable soft tip medical device and method of usage |
| US8535243B2 (en) | 2008-09-10 | 2013-09-17 | Boston Scientific Scimed, Inc. | Medical devices and tapered tubular members for use in medical devices |
| US8545418B2 (en) | 2004-08-25 | 2013-10-01 | Richard R. Heuser | Systems and methods for ablation of occlusions within blood vessels |
| US8551020B2 (en) | 2006-09-13 | 2013-10-08 | Boston Scientific Scimed, Inc. | Crossing guidewire |
| US8551021B2 (en) | 2010-03-31 | 2013-10-08 | Boston Scientific Scimed, Inc. | Guidewire with an improved flexural rigidity profile |
| US8632562B2 (en) | 2005-10-03 | 2014-01-21 | Cook Medical Technologies Llc | Embolic protection device |
| US8795315B2 (en) | 2004-10-06 | 2014-08-05 | Cook Medical Technologies Llc | Emboli capturing device having a coil and method for capturing emboli |
| US8795254B2 (en) | 2008-12-10 | 2014-08-05 | Boston Scientific Scimed, Inc. | Medical devices with a slotted tubular member having improved stress distribution |
| US8795202B2 (en) | 2011-02-04 | 2014-08-05 | Boston Scientific Scimed, Inc. | Guidewires and methods for making and using the same |
| US8821477B2 (en) | 2007-08-06 | 2014-09-02 | Boston Scientific Scimed, Inc. | Alternative micromachined structures |
| US8945169B2 (en) | 2005-03-15 | 2015-02-03 | Cook Medical Technologies Llc | Embolic protection device |
| US9072874B2 (en) | 2011-05-13 | 2015-07-07 | Boston Scientific Scimed, Inc. | Medical devices with a heat transfer region and a heat sink region and methods for manufacturing medical devices |
| CN104799983A (en)* | 2015-05-04 | 2015-07-29 | 苏州英络医疗器械有限公司 | Seamless stent and manufacturing method thereof |
| US9138307B2 (en) | 2007-09-14 | 2015-09-22 | Cook Medical Technologies Llc | Expandable device for treatment of a stricture in a body vessel |
| WO2016177323A1 (en)* | 2015-05-04 | 2016-11-10 | 苏州茵络医疗器械有限公司 | Intravascular stent and manufacturing method thereof |
| US9808595B2 (en) | 2007-08-07 | 2017-11-07 | Boston Scientific Scimed, Inc | Microfabricated catheter with improved bonding structure |
| US9901434B2 (en) | 2007-02-27 | 2018-02-27 | Cook Medical Technologies Llc | Embolic protection device including a Z-stent waist band |
| US9907639B2 (en) | 2006-09-19 | 2018-03-06 | Cook Medical Technologies Llc | Apparatus and methods for in situ embolic protection |
| US20180132873A1 (en)* | 2016-11-14 | 2018-05-17 | Covidien Lp | Embolic protection system including multiple filter bodies |
| US20190192177A1 (en)* | 2017-12-22 | 2019-06-27 | Acclarent, Inc. | Reusable navigation guidewire |
| WO2023117159A1 (en)* | 2021-12-21 | 2023-06-29 | Anaconda Biomed, Sl | An intravascular device with an improved attachment of its elements and a method of manufacturing thereof |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8337519B2 (en)* | 2003-07-10 | 2012-12-25 | Boston Scientific Scimed, Inc. | Embolic protection filtering device |
| US8808323B2 (en)* | 2010-12-21 | 2014-08-19 | BiO2 Medical, Inc. | Configuration and method for fixation of a filter to a catheter |
| US9636485B2 (en) | 2013-01-17 | 2017-05-02 | Abbott Cardiovascular Systems, Inc. | Methods for counteracting rebounding effects during solid state resistance welding of dissimilar materials |
| US10071229B2 (en) | 2015-04-14 | 2018-09-11 | Abbott Cardiovascular Systems, Inc. | Mechanisms for improving the stiffness transition across a dissimilar metal weld joint |
| SE1750993A1 (en) | 2017-08-15 | 2019-02-16 | Cavis Tech Ab | Pressure catheter and guide wire assembly |
| CN112638317B (en)* | 2018-05-30 | 2024-07-02 | 艾露姆技术股份有限公司 | Integrated thrombectomy and filtration device and method of use |
| JP2021186076A (en)* | 2020-05-27 | 2021-12-13 | 朝日インテック株式会社 | Medical device |
| US12178974B2 (en) | 2021-01-21 | 2024-12-31 | Abbott Cardiovascular Systems Inc. | Guidewire and method of use |
Citations (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3952747A (en)* | 1974-03-28 | 1976-04-27 | Kimmell Jr Garman O | Filter and filter insertion instrument |
| US4425908A (en)* | 1981-10-22 | 1984-01-17 | Beth Israel Hospital | Blood clot filter |
| US4590938A (en)* | 1984-05-04 | 1986-05-27 | Segura Joseph W | Medical retriever device |
| US4650466A (en)* | 1985-11-01 | 1987-03-17 | Angiobrade Partners | Angioplasty device |
| US4723549A (en)* | 1986-09-18 | 1988-02-09 | Wholey Mark H | Method and apparatus for dilating blood vessels |
| US4794928A (en)* | 1987-06-10 | 1989-01-03 | Kletschka Harold D | Angioplasty device and method of using the same |
| US4807626A (en)* | 1985-02-14 | 1989-02-28 | Mcgirr Douglas B | Stone extractor and method |
| US4842579A (en)* | 1984-05-14 | 1989-06-27 | Surgical Systems & Instruments, Inc. | Atherectomy device |
| US4904657A (en)* | 1987-09-24 | 1990-02-27 | Kissei Pharmaceutical Co., Ltd. | 4H-quinolizin-4-one compounds exhibiting therapeutic activities |
| US4921484A (en)* | 1988-07-25 | 1990-05-01 | Cordis Corporation | Mesh balloon catheter device |
| US4921478A (en)* | 1988-02-23 | 1990-05-01 | C. R. Bard, Inc. | Cerebral balloon angioplasty system |
| US4925445A (en)* | 1983-09-16 | 1990-05-15 | Fuji Terumo Co., Ltd. | Guide wire for catheter |
| US4926858A (en)* | 1984-05-30 | 1990-05-22 | Devices For Vascular Intervention, Inc. | Atherectomy device for severe occlusions |
| US4991602A (en)* | 1989-06-27 | 1991-02-12 | Flexmedics Corporation | Flexible guide wire with safety tip |
| US4998539A (en)* | 1987-12-18 | 1991-03-12 | Delsanti Gerard L | Method of using removable endo-arterial devices to repair detachments in the arterial walls |
| US5002560A (en)* | 1989-09-08 | 1991-03-26 | Advanced Cardiovascular Systems, Inc. | Expandable cage catheter with a rotatable guide |
| US5011488A (en)* | 1988-12-07 | 1991-04-30 | Robert Ginsburg | Thrombus extraction system |
| US5100423A (en)* | 1990-08-21 | 1992-03-31 | Medical Engineering & Development Institute, Inc. | Ablation catheter |
| US5102415A (en)* | 1989-09-06 | 1992-04-07 | Guenther Rolf W | Apparatus for removing blood clots from arteries and veins |
| US5111829A (en)* | 1989-06-28 | 1992-05-12 | Boston Scientific Corporation | Steerable highly elongated guidewire |
| US5120308A (en)* | 1989-05-03 | 1992-06-09 | Progressive Angioplasty Systems, Inc. | Catheter with high tactile guide wire |
| US5133733A (en)* | 1989-11-28 | 1992-07-28 | William Cook Europe A/S | Collapsible filter for introduction in a blood vessel of a patient |
| US5213111A (en)* | 1991-07-10 | 1993-05-25 | Cook Incorporated | Composite wire guide construction |
| US5224953A (en)* | 1992-05-01 | 1993-07-06 | The Beth Israel Hospital Association | Method for treatment of obstructive portions of urinary passageways |
| US5230348A (en)* | 1990-10-12 | 1993-07-27 | Nippon Seisen Co., Ltd. | Guide wire for a catheter |
| US5238004A (en)* | 1990-04-10 | 1993-08-24 | Boston Scientific Corporation | High elongation linear elastic guidewire |
| US5329942A (en)* | 1990-08-14 | 1994-07-19 | Cook, Incorporated | Method for filtering blood in a blood vessel of a patient |
| US5330484A (en)* | 1990-08-16 | 1994-07-19 | William Cook Europe A/S | Device for fragmentation of thrombi |
| US5341818A (en)* | 1992-12-22 | 1994-08-30 | Advanced Cardiovascular Systems, Inc. | Guidewire with superelastic distal portion |
| US5402799A (en)* | 1993-06-29 | 1995-04-04 | Cordis Corporation | Guidewire having flexible floppy tip |
| US5409015A (en)* | 1993-05-11 | 1995-04-25 | Target Therapeutics, Inc. | Deformable tip super elastic guidewire |
| US5421832A (en)* | 1989-12-13 | 1995-06-06 | Lefebvre; Jean-Marie | Filter-catheter and method of manufacturing same |
| US5423742A (en)* | 1989-09-12 | 1995-06-13 | Schneider Europe | Method for the widening of strictures in vessels carrying body fluid |
| US5488959A (en)* | 1993-12-27 | 1996-02-06 | Cordis Corporation | Medical guidewire and welding process |
| US5536242A (en)* | 1994-07-01 | 1996-07-16 | Scimed Life Systems, Inc. | Intravascular device utilizing fluid to extract occlusive material |
| US5549626A (en)* | 1994-12-23 | 1996-08-27 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Vena caval filter |
| US5636996A (en)* | 1994-06-28 | 1997-06-10 | The Whitaker Corporation | Anisotropic interposer pad |
| US5658296A (en)* | 1994-11-21 | 1997-08-19 | Boston Scientific Corporation | Method for making surgical retrieval baskets |
| US5720764A (en)* | 1994-06-11 | 1998-02-24 | Naderlinger; Eduard | Vena cava thrombus filter |
| US5728066A (en)* | 1995-12-13 | 1998-03-17 | Daneshvar; Yousef | Injection systems and methods |
| US5749848A (en)* | 1995-11-13 | 1998-05-12 | Cardiovascular Imaging Systems, Inc. | Catheter system having imaging, balloon angioplasty, and stent deployment capabilities, and method of use for guided stent deployment |
| US5749837A (en)* | 1993-05-11 | 1998-05-12 | Target Therapeutics, Inc. | Enhanced lubricity guidewire |
| US5769796A (en)* | 1993-05-11 | 1998-06-23 | Target Therapeutics, Inc. | Super-elastic composite guidewire |
| US5769816A (en)* | 1995-11-07 | 1998-06-23 | Embol-X, Inc. | Cannula with associated filter |
| US5772609A (en)* | 1993-05-11 | 1998-06-30 | Target Therapeutics, Inc. | Guidewire with variable flexibility due to polymeric coatings |
| US5776100A (en)* | 1995-09-27 | 1998-07-07 | Interventional Innovations Corporation | Nickel titanium guide wires for occlusion and drug delivery |
| US5779716A (en)* | 1995-10-06 | 1998-07-14 | Metamorphic Surgical Devices, Inc. | Device for removing solid objects from body canals, cavities and organs |
| US5782741A (en)* | 1996-11-12 | 1998-07-21 | Guidant Coropration | Two-stage treatment wire |
| US5792157A (en)* | 1992-11-13 | 1998-08-11 | Scimed Life Systems, Inc. | Expandable intravascular occlusion material removal devices and methods of use |
| US5795322A (en)* | 1995-04-10 | 1998-08-18 | Cordis Corporation | Catheter with filter and thrombus-discharge device |
| US5876367A (en)* | 1996-12-05 | 1999-03-02 | Embol-X, Inc. | Cerebral protection during carotid endarterectomy and downstream vascular protection during other surgeries |
| US5895399A (en)* | 1996-07-17 | 1999-04-20 | Embol-X Inc. | Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries |
| US5910154A (en)* | 1997-05-08 | 1999-06-08 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment |
| US5925016A (en)* | 1995-09-27 | 1999-07-20 | Xrt Corp. | Systems and methods for drug delivery including treating thrombosis by driving a drug or lytic agent through the thrombus by pressure |
| US5925060A (en)* | 1998-03-13 | 1999-07-20 | B. Braun Celsa | Covered self-expanding vascular occlusion device |
| US5925062A (en)* | 1992-09-02 | 1999-07-20 | Board Of Regents, The University Of Texas System | Intravascular device |
| US5931178A (en)* | 1996-03-19 | 1999-08-03 | Design Systems, Inc. | High-speed water jet blocker |
| US6013085A (en)* | 1997-11-07 | 2000-01-11 | Howard; John | Method for treating stenosis of the carotid artery |
| US6039699A (en)* | 1996-01-22 | 2000-03-21 | Cordis Corporation | Stiff catheter guidewire with flexible distal portion |
| US6051014A (en)* | 1998-10-13 | 2000-04-18 | Embol-X, Inc. | Percutaneous filtration catheter for valve repair surgery and methods of use |
| US6051015A (en)* | 1997-05-08 | 2000-04-18 | Embol-X, Inc. | Modular filter with delivery system |
| US6053932A (en)* | 1997-03-06 | 2000-04-25 | Scimed Life Systems, Inc. | Distal protection device |
| US6059814A (en)* | 1997-06-02 | 2000-05-09 | Medtronic Ave., Inc. | Filter for filtering fluid in a bodily passageway |
| US6066149A (en)* | 1997-09-30 | 2000-05-23 | Target Therapeutics, Inc. | Mechanical clot treatment device with distal filter |
| US6066158A (en)* | 1996-07-25 | 2000-05-23 | Target Therapeutics, Inc. | Mechanical clot encasing and removal wire |
| US6068623A (en)* | 1997-03-06 | 2000-05-30 | Percusurge, Inc. | Hollow medical wires and methods of constructing same |
| US6068645A (en)* | 1999-06-07 | 2000-05-30 | Tu; Hosheng | Filter system and methods for removing blood clots and biological material |
| US6086605A (en)* | 1997-04-16 | 2000-07-11 | Embol-X, Inc. | Cannula with associated filter and methods of use during cardiac surgery |
| US6168571B1 (en)* | 1997-04-15 | 2001-01-02 | Symbiosis Corporation | Linear elastic member |
| US6168579B1 (en)* | 1999-08-04 | 2001-01-02 | Scimed Life Systems, Inc. | Filter flush system and methods of use |
| US6171328B1 (en)* | 1999-11-09 | 2001-01-09 | Embol-X, Inc. | Intravascular catheter filter with interlocking petal design and methods of use |
| US6171327B1 (en)* | 1999-02-24 | 2001-01-09 | Scimed Life Systems, Inc. | Intravascular filter and method |
| US6179861B1 (en)* | 1999-07-30 | 2001-01-30 | Incept Llc | Vascular device having one or more articulation regions and methods of use |
| US6179859B1 (en)* | 1999-07-16 | 2001-01-30 | Baff Llc | Emboli filtration system and methods of use |
| US6190332B1 (en)* | 1998-02-19 | 2001-02-20 | Percusurge, Inc. | Core wire with shapeable tip |
| US6203561B1 (en)* | 1999-07-30 | 2001-03-20 | Incept Llc | Integrated vascular device having thrombectomy element and vascular filter and methods of use |
| US6206868B1 (en)* | 1998-03-13 | 2001-03-27 | Arteria Medical Science, Inc. | Protective device and method against embolization during treatment of carotid artery disease |
| US6214026B1 (en)* | 1999-07-30 | 2001-04-10 | Incept Llc | Delivery system for a vascular device with articulation region |
| US6221006B1 (en)* | 1998-02-10 | 2001-04-24 | Artemis Medical Inc. | Entrapping apparatus and method for use |
| US6231544B1 (en)* | 1996-05-14 | 2001-05-15 | Embol-X, Inc. | Cardioplegia balloon cannula |
| US6235044B1 (en)* | 1999-08-04 | 2001-05-22 | Scimed Life Systems, Inc. | Percutaneous catheter and guidewire for filtering during ablation of mycardial or vascular tissue |
| US6238412B1 (en)* | 1997-11-12 | 2001-05-29 | William Dubrul | Biological passageway occlusion removal |
| US6245088B1 (en)* | 1997-07-07 | 2001-06-12 | Samuel R. Lowery | Retrievable umbrella sieve and method of use |
| US6245087B1 (en)* | 1999-08-03 | 2001-06-12 | Embol-X, Inc. | Variable expansion frame system for deploying medical devices and methods of use |
| US6258115B1 (en)* | 1997-04-23 | 2001-07-10 | Artemis Medical, Inc. | Bifurcated stent and distal protection system |
| US6264672B1 (en)* | 1999-10-25 | 2001-07-24 | Biopsy Sciences, Llc | Emboli capturing device |
| US6264663B1 (en)* | 1995-10-06 | 2001-07-24 | Metamorphic Surgical Devices, Llc | Device for removing solid objects from body canals, cavities and organs including an invertable basket |
| US20010009982A1 (en)* | 1997-12-05 | 2001-07-26 | Ferrera David A. | Coated superelastic stent |
| US6344049B1 (en)* | 1999-08-17 | 2002-02-05 | Scion Cardio-Vascular, Inc. | Filter for embolic material mounted on expandable frame and associated deployment system |
| US6352515B1 (en)* | 1999-12-13 | 2002-03-05 | Advanced Cardiovascular Systems, Inc. | NiTi alloyed guidewires |
| US6379369B1 (en)* | 1990-12-18 | 2002-04-30 | Advanced Cardiovascular Systems, Inc. | Intracorporeal device with NiTi tubular member |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3472230A (en) | 1966-12-19 | 1969-10-14 | Fogarty T J | Umbrella catheter |
| US3996938A (en) | 1975-07-10 | 1976-12-14 | Clark Iii William T | Expanding mesh catheter |
| US4643184A (en) | 1982-09-29 | 1987-02-17 | Mobin Uddin Kazi | Embolus trap |
| US4790813A (en) | 1984-12-17 | 1988-12-13 | Intravascular Surgical Instruments, Inc. | Method and apparatus for surgically removing remote deposits |
| US4706671A (en) | 1985-05-02 | 1987-11-17 | Weinrib Harry P | Catheter with coiled tip |
| US4662885A (en) | 1985-09-03 | 1987-05-05 | Becton, Dickinson And Company | Percutaneously deliverable intravascular filter prosthesis |
| US4790812A (en) | 1985-11-15 | 1988-12-13 | Hawkins Jr Irvin F | Apparatus and method for removing a target object from a body passsageway |
| US4857045A (en) | 1987-04-30 | 1989-08-15 | Schneider (Usa) Inc., A Pfizer Company | Atherectomy catheter |
| US4873978A (en) | 1987-12-04 | 1989-10-17 | Robert Ginsburg | Device and method for emboli retrieval |
| US4886061A (en) | 1988-02-09 | 1989-12-12 | Medinnovations, Inc. | Expandable pullback atherectomy catheter system |
| US4969891A (en) | 1989-03-06 | 1990-11-13 | Gewertz Bruce L | Removable vascular filter |
| US5071407A (en) | 1990-04-12 | 1991-12-10 | Schneider (U.S.A.) Inc. | Radially expandable fixation member |
| US5160342A (en) | 1990-08-16 | 1992-11-03 | Evi Corp. | Endovascular filter and method for use thereof |
| US5415630A (en) | 1991-07-17 | 1995-05-16 | Gory; Pierre | Method for removably implanting a blood filter in a vein of the human body |
| US5192286A (en) | 1991-07-26 | 1993-03-09 | Regents Of The University Of California | Method and device for retrieving materials from body lumens |
| US5626605A (en) | 1991-12-30 | 1997-05-06 | Scimed Life Systems, Inc. | Thrombosis filter |
| US5324304A (en) | 1992-06-18 | 1994-06-28 | William Cook Europe A/S | Introduction catheter set for a collapsible self-expandable implant |
| US5365943A (en)* | 1993-03-12 | 1994-11-22 | C. R. Bard, Inc. | Anatomically matched steerable PTCA guidewire |
| US5419774A (en) | 1993-07-13 | 1995-05-30 | Scimed Life Systems, Inc. | Thrombus extraction device |
| US5462529A (en) | 1993-09-29 | 1995-10-31 | Technology Development Center | Adjustable treatment chamber catheter |
| ES2340142T3 (en) | 1994-07-08 | 2010-05-31 | Ev3 Inc. | SYSTEM TO CARRY OUT AN INTRAVASCULAR PROCEDURE. |
| US5807398A (en) | 1995-04-28 | 1998-09-15 | Shaknovich; Alexander | Shuttle stent delivery catheter |
| US5833650A (en) | 1995-06-05 | 1998-11-10 | Percusurge, Inc. | Catheter apparatus and method for treating occluded vessels |
| JPH0994298A (en)* | 1995-09-28 | 1997-04-08 | Terumo Corp | Guide wire |
| US6488637B1 (en)* | 1996-04-30 | 2002-12-03 | Target Therapeutics, Inc. | Composite endovascular guidewire |
| US5669933A (en) | 1996-07-17 | 1997-09-23 | Nitinol Medical Technologies, Inc. | Removable embolus blood clot filter |
| US6001068A (en) | 1996-10-22 | 1999-12-14 | Terumo Kabushiki Kaisha | Guide wire having tubular connector with helical slits |
| US5800457A (en) | 1997-03-05 | 1998-09-01 | Gelbfish; Gary A. | Intravascular filter and associated methodology |
| US6152946A (en) | 1998-03-05 | 2000-11-28 | Scimed Life Systems, Inc. | Distal protection device and method |
| US5827324A (en)* | 1997-03-06 | 1998-10-27 | Scimed Life Systems, Inc. | Distal protection device |
| JP3607456B2 (en)* | 1997-03-31 | 2005-01-05 | テルモ株式会社 | Guide wire |
| US5800525A (en) | 1997-06-04 | 1998-09-01 | Vascular Science, Inc. | Blood filter |
| US5848964A (en) | 1997-06-06 | 1998-12-15 | Samuels; Shaun Lawrence Wilkie | Temporary inflatable filter device and method of use |
| WO1999022673A1 (en) | 1997-11-03 | 1999-05-14 | C.R. Bard, Inc. | Temporary vascular filter guide wire |
| US6277139B1 (en) | 1999-04-01 | 2001-08-21 | Scion Cardio-Vascular, Inc. | Vascular protection and embolic material retriever |
| US6142987A (en) | 1999-08-03 | 2000-11-07 | Scimed Life Systems, Inc. | Guided filter with support wire and methods of use |
| US6371971B1 (en)* | 1999-11-15 | 2002-04-16 | Scimed Life Systems, Inc. | Guidewire filter and methods of use |
| EP1238639B1 (en)* | 2001-03-07 | 2006-06-07 | Bavaria Medizin Technologie GmbH | Filter device for vessel systems |
- 2002
- 2002-12-13USUS10/318,907patent/US20040116831A1/ennot_activeAbandoned
- 2003
- 2003-12-11CACA2509676Apatent/CA2509676C/ennot_activeExpired - Fee Related
- 2003-12-11JPJP2004560843Apatent/JP2006509591A/enactivePending
- 2003-12-11AUAU2003297015Apatent/AU2003297015A1/ennot_activeAbandoned
- 2003-12-11EPEP03813424Apatent/EP1578469A2/ennot_activeWithdrawn
- 2003-12-11WOPCT/US2003/039689patent/WO2004054652A2/enactiveApplication Filing
- 2006
- 2006-12-08USUS11/608,619patent/US8083689B2/ennot_activeExpired - Fee Related
Patent Citations (100)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3952747A (en)* | 1974-03-28 | 1976-04-27 | Kimmell Jr Garman O | Filter and filter insertion instrument |
| US4425908A (en)* | 1981-10-22 | 1984-01-17 | Beth Israel Hospital | Blood clot filter |
| US4925445A (en)* | 1983-09-16 | 1990-05-15 | Fuji Terumo Co., Ltd. | Guide wire for catheter |
| US4590938A (en)* | 1984-05-04 | 1986-05-27 | Segura Joseph W | Medical retriever device |
| US4842579B1 (en)* | 1984-05-14 | 1995-10-31 | Surgical Systems & Instr Inc | Atherectomy device |
| US4842579A (en)* | 1984-05-14 | 1989-06-27 | Surgical Systems & Instruments, Inc. | Atherectomy device |
| US4926858A (en)* | 1984-05-30 | 1990-05-22 | Devices For Vascular Intervention, Inc. | Atherectomy device for severe occlusions |
| US4807626A (en)* | 1985-02-14 | 1989-02-28 | Mcgirr Douglas B | Stone extractor and method |
| US4650466A (en)* | 1985-11-01 | 1987-03-17 | Angiobrade Partners | Angioplasty device |
| US4723549A (en)* | 1986-09-18 | 1988-02-09 | Wholey Mark H | Method and apparatus for dilating blood vessels |
| US4794928A (en)* | 1987-06-10 | 1989-01-03 | Kletschka Harold D | Angioplasty device and method of using the same |
| US4904657A (en)* | 1987-09-24 | 1990-02-27 | Kissei Pharmaceutical Co., Ltd. | 4H-quinolizin-4-one compounds exhibiting therapeutic activities |
| US4998539A (en)* | 1987-12-18 | 1991-03-12 | Delsanti Gerard L | Method of using removable endo-arterial devices to repair detachments in the arterial walls |
| US4921478A (en)* | 1988-02-23 | 1990-05-01 | C. R. Bard, Inc. | Cerebral balloon angioplasty system |
| US4921484A (en)* | 1988-07-25 | 1990-05-01 | Cordis Corporation | Mesh balloon catheter device |
| US5011488A (en)* | 1988-12-07 | 1991-04-30 | Robert Ginsburg | Thrombus extraction system |
| US5120308A (en)* | 1989-05-03 | 1992-06-09 | Progressive Angioplasty Systems, Inc. | Catheter with high tactile guide wire |
| US4991602A (en)* | 1989-06-27 | 1991-02-12 | Flexmedics Corporation | Flexible guide wire with safety tip |
| US5111829A (en)* | 1989-06-28 | 1992-05-12 | Boston Scientific Corporation | Steerable highly elongated guidewire |
| US5102415A (en)* | 1989-09-06 | 1992-04-07 | Guenther Rolf W | Apparatus for removing blood clots from arteries and veins |
| US5002560A (en)* | 1989-09-08 | 1991-03-26 | Advanced Cardiovascular Systems, Inc. | Expandable cage catheter with a rotatable guide |
| US5423742A (en)* | 1989-09-12 | 1995-06-13 | Schneider Europe | Method for the widening of strictures in vessels carrying body fluid |
| US5133733A (en)* | 1989-11-28 | 1992-07-28 | William Cook Europe A/S | Collapsible filter for introduction in a blood vessel of a patient |
| US5421832A (en)* | 1989-12-13 | 1995-06-06 | Lefebvre; Jean-Marie | Filter-catheter and method of manufacturing same |
| US5238004A (en)* | 1990-04-10 | 1993-08-24 | Boston Scientific Corporation | High elongation linear elastic guidewire |
| US5329942A (en)* | 1990-08-14 | 1994-07-19 | Cook, Incorporated | Method for filtering blood in a blood vessel of a patient |
| US5330484A (en)* | 1990-08-16 | 1994-07-19 | William Cook Europe A/S | Device for fragmentation of thrombi |
| US5100423A (en)* | 1990-08-21 | 1992-03-31 | Medical Engineering & Development Institute, Inc. | Ablation catheter |
| US5230348A (en)* | 1990-10-12 | 1993-07-27 | Nippon Seisen Co., Ltd. | Guide wire for a catheter |
| US6379369B1 (en)* | 1990-12-18 | 2002-04-30 | Advanced Cardiovascular Systems, Inc. | Intracorporeal device with NiTi tubular member |
| US5213111A (en)* | 1991-07-10 | 1993-05-25 | Cook Incorporated | Composite wire guide construction |
| US5224953A (en)* | 1992-05-01 | 1993-07-06 | The Beth Israel Hospital Association | Method for treatment of obstructive portions of urinary passageways |
| US5925062A (en)* | 1992-09-02 | 1999-07-20 | Board Of Regents, The University Of Texas System | Intravascular device |
| US5792157A (en)* | 1992-11-13 | 1998-08-11 | Scimed Life Systems, Inc. | Expandable intravascular occlusion material removal devices and methods of use |
| US5341818A (en)* | 1992-12-22 | 1994-08-30 | Advanced Cardiovascular Systems, Inc. | Guidewire with superelastic distal portion |
| US5409015A (en)* | 1993-05-11 | 1995-04-25 | Target Therapeutics, Inc. | Deformable tip super elastic guidewire |
| US5749837A (en)* | 1993-05-11 | 1998-05-12 | Target Therapeutics, Inc. | Enhanced lubricity guidewire |
| US5769796A (en)* | 1993-05-11 | 1998-06-23 | Target Therapeutics, Inc. | Super-elastic composite guidewire |
| US5772609A (en)* | 1993-05-11 | 1998-06-30 | Target Therapeutics, Inc. | Guidewire with variable flexibility due to polymeric coatings |
| US5402799A (en)* | 1993-06-29 | 1995-04-04 | Cordis Corporation | Guidewire having flexible floppy tip |
| US5488959A (en)* | 1993-12-27 | 1996-02-06 | Cordis Corporation | Medical guidewire and welding process |
| US5720764A (en)* | 1994-06-11 | 1998-02-24 | Naderlinger; Eduard | Vena cava thrombus filter |
| US5636996A (en)* | 1994-06-28 | 1997-06-10 | The Whitaker Corporation | Anisotropic interposer pad |
| US5536242A (en)* | 1994-07-01 | 1996-07-16 | Scimed Life Systems, Inc. | Intravascular device utilizing fluid to extract occlusive material |
| US5658296A (en)* | 1994-11-21 | 1997-08-19 | Boston Scientific Corporation | Method for making surgical retrieval baskets |
| US5549626A (en)* | 1994-12-23 | 1996-08-27 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Vena caval filter |
| US5795322A (en)* | 1995-04-10 | 1998-08-18 | Cordis Corporation | Catheter with filter and thrombus-discharge device |
| US5925016A (en)* | 1995-09-27 | 1999-07-20 | Xrt Corp. | Systems and methods for drug delivery including treating thrombosis by driving a drug or lytic agent through the thrombus by pressure |
| US5776100A (en)* | 1995-09-27 | 1998-07-07 | Interventional Innovations Corporation | Nickel titanium guide wires for occlusion and drug delivery |
| US5779716A (en)* | 1995-10-06 | 1998-07-14 | Metamorphic Surgical Devices, Inc. | Device for removing solid objects from body canals, cavities and organs |
| US6264663B1 (en)* | 1995-10-06 | 2001-07-24 | Metamorphic Surgical Devices, Llc | Device for removing solid objects from body canals, cavities and organs including an invertable basket |
| US6235045B1 (en)* | 1995-11-07 | 2001-05-22 | Embol-X, Inc. | Cannula with associated filter and methods of use |
| US5769816A (en)* | 1995-11-07 | 1998-06-23 | Embol-X, Inc. | Cannula with associated filter |
| US5749848A (en)* | 1995-11-13 | 1998-05-12 | Cardiovascular Imaging Systems, Inc. | Catheter system having imaging, balloon angioplasty, and stent deployment capabilities, and method of use for guided stent deployment |
| US5728066A (en)* | 1995-12-13 | 1998-03-17 | Daneshvar; Yousef | Injection systems and methods |
| US6039699A (en)* | 1996-01-22 | 2000-03-21 | Cordis Corporation | Stiff catheter guidewire with flexible distal portion |
| US5931178A (en)* | 1996-03-19 | 1999-08-03 | Design Systems, Inc. | High-speed water jet blocker |
| US6231544B1 (en)* | 1996-05-14 | 2001-05-15 | Embol-X, Inc. | Cardioplegia balloon cannula |
| US6179851B1 (en)* | 1996-07-17 | 2001-01-30 | Scimed Life Systems, Inc. | Guiding catheter for positioning a medical device within an artery |
| US6010522A (en)* | 1996-07-17 | 2000-01-04 | Embol-X, Inc. | Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries |
| US5895399A (en)* | 1996-07-17 | 1999-04-20 | Embol-X Inc. | Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries |
| US6066158A (en)* | 1996-07-25 | 2000-05-23 | Target Therapeutics, Inc. | Mechanical clot encasing and removal wire |
| US5782741A (en)* | 1996-11-12 | 1998-07-21 | Guidant Coropration | Two-stage treatment wire |
| US5876367A (en)* | 1996-12-05 | 1999-03-02 | Embol-X, Inc. | Cerebral protection during carotid endarterectomy and downstream vascular protection during other surgeries |
| US6245089B1 (en)* | 1997-03-06 | 2001-06-12 | Scimed Life Systems, Inc. | Distal protection device and method |
| US6068623A (en)* | 1997-03-06 | 2000-05-30 | Percusurge, Inc. | Hollow medical wires and methods of constructing same |
| US6053932A (en)* | 1997-03-06 | 2000-04-25 | Scimed Life Systems, Inc. | Distal protection device |
| US6168571B1 (en)* | 1997-04-15 | 2001-01-02 | Symbiosis Corporation | Linear elastic member |
| US6086605A (en)* | 1997-04-16 | 2000-07-11 | Embol-X, Inc. | Cannula with associated filter and methods of use during cardiac surgery |
| US6258115B1 (en)* | 1997-04-23 | 2001-07-10 | Artemis Medical, Inc. | Bifurcated stent and distal protection system |
| US6027520A (en)* | 1997-05-08 | 2000-02-22 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
| US6224620B1 (en)* | 1997-05-08 | 2001-05-01 | Embol-X, Inc. | Devices and methods for protecting a patient from embolic material during surgery |
| US5910154A (en)* | 1997-05-08 | 1999-06-08 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment |
| US5911734A (en)* | 1997-05-08 | 1999-06-15 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
| US6042598A (en)* | 1997-05-08 | 2000-03-28 | Embol-X Inc. | Method of protecting a patient from embolization during cardiac surgery |
| US6051015A (en)* | 1997-05-08 | 2000-04-18 | Embol-X, Inc. | Modular filter with delivery system |
| US6059814A (en)* | 1997-06-02 | 2000-05-09 | Medtronic Ave., Inc. | Filter for filtering fluid in a bodily passageway |
| US6245088B1 (en)* | 1997-07-07 | 2001-06-12 | Samuel R. Lowery | Retrievable umbrella sieve and method of use |
| US6066149A (en)* | 1997-09-30 | 2000-05-23 | Target Therapeutics, Inc. | Mechanical clot treatment device with distal filter |
| US6013085A (en)* | 1997-11-07 | 2000-01-11 | Howard; John | Method for treating stenosis of the carotid artery |
| US6238412B1 (en)* | 1997-11-12 | 2001-05-29 | William Dubrul | Biological passageway occlusion removal |
| US20010009982A1 (en)* | 1997-12-05 | 2001-07-26 | Ferrera David A. | Coated superelastic stent |
| US6221006B1 (en)* | 1998-02-10 | 2001-04-24 | Artemis Medical Inc. | Entrapping apparatus and method for use |
| US6190332B1 (en)* | 1998-02-19 | 2001-02-20 | Percusurge, Inc. | Core wire with shapeable tip |
| US6206868B1 (en)* | 1998-03-13 | 2001-03-27 | Arteria Medical Science, Inc. | Protective device and method against embolization during treatment of carotid artery disease |
| US5925060A (en)* | 1998-03-13 | 1999-07-20 | B. Braun Celsa | Covered self-expanding vascular occlusion device |
| US6051014A (en)* | 1998-10-13 | 2000-04-18 | Embol-X, Inc. | Percutaneous filtration catheter for valve repair surgery and methods of use |
| US6171327B1 (en)* | 1999-02-24 | 2001-01-09 | Scimed Life Systems, Inc. | Intravascular filter and method |
| US6068645A (en)* | 1999-06-07 | 2000-05-30 | Tu; Hosheng | Filter system and methods for removing blood clots and biological material |
| US6179859B1 (en)* | 1999-07-16 | 2001-01-30 | Baff Llc | Emboli filtration system and methods of use |
| US6214026B1 (en)* | 1999-07-30 | 2001-04-10 | Incept Llc | Delivery system for a vascular device with articulation region |
| US6203561B1 (en)* | 1999-07-30 | 2001-03-20 | Incept Llc | Integrated vascular device having thrombectomy element and vascular filter and methods of use |
| US6179861B1 (en)* | 1999-07-30 | 2001-01-30 | Incept Llc | Vascular device having one or more articulation regions and methods of use |
| US6245087B1 (en)* | 1999-08-03 | 2001-06-12 | Embol-X, Inc. | Variable expansion frame system for deploying medical devices and methods of use |
| US6168579B1 (en)* | 1999-08-04 | 2001-01-02 | Scimed Life Systems, Inc. | Filter flush system and methods of use |
| US6235044B1 (en)* | 1999-08-04 | 2001-05-22 | Scimed Life Systems, Inc. | Percutaneous catheter and guidewire for filtering during ablation of mycardial or vascular tissue |
| US6344049B1 (en)* | 1999-08-17 | 2002-02-05 | Scion Cardio-Vascular, Inc. | Filter for embolic material mounted on expandable frame and associated deployment system |
| US6264672B1 (en)* | 1999-10-25 | 2001-07-24 | Biopsy Sciences, Llc | Emboli capturing device |
| US6171328B1 (en)* | 1999-11-09 | 2001-01-09 | Embol-X, Inc. | Intravascular catheter filter with interlocking petal design and methods of use |
| US6352515B1 (en)* | 1999-12-13 | 2002-03-05 | Advanced Cardiovascular Systems, Inc. | NiTi alloyed guidewires |
Cited By (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8449526B2 (en) | 2001-07-05 | 2013-05-28 | Boston Scientific Scimed, Inc. | Torqueable soft tip medical device and method of usage |
| US20070287955A1 (en)* | 2002-07-25 | 2007-12-13 | Boston Scientific Scimed, Inc. | Tubular member having tapered transition for use in a medical device |
| US7914467B2 (en) | 2002-07-25 | 2011-03-29 | Boston Scientific Scimed, Inc. | Tubular member having tapered transition for use in a medical device |
| US8377035B2 (en) | 2003-01-17 | 2013-02-19 | Boston Scientific Scimed, Inc. | Unbalanced reinforcement members for medical device |
| US7914492B2 (en) | 2003-01-27 | 2011-03-29 | Heuser Richard R | Catheter introducer system |
| US20070123805A1 (en)* | 2003-02-26 | 2007-05-31 | Boston Scientific Scimed, Inc. | Elongated intracorporal medical device |
| US7402141B2 (en) | 2003-08-27 | 2008-07-22 | Heuser Richard R | Catheter guidewire system using concentric wires |
| US20060047222A1 (en)* | 2003-08-27 | 2006-03-02 | Heuser Richard R | Catheter guidewire system using concentric wires |
| US7824345B2 (en) | 2003-12-22 | 2010-11-02 | Boston Scientific Scimed, Inc. | Medical device with push force limiter |
| US7976516B2 (en) | 2004-06-25 | 2011-07-12 | Lumen Biomedical, Inc. | Medical device having mechanically interlocked segments |
| US20060006649A1 (en)* | 2004-06-25 | 2006-01-12 | Galdonik Jason A | Medical device having mechanically interlocked segments |
| US20090012429A1 (en)* | 2004-08-25 | 2009-01-08 | Heuser Richard R | Catheter guidewire system using concentric wires |
| US8545418B2 (en) | 2004-08-25 | 2013-10-01 | Richard R. Heuser | Systems and methods for ablation of occlusions within blood vessels |
| US8795315B2 (en) | 2004-10-06 | 2014-08-05 | Cook Medical Technologies Llc | Emboli capturing device having a coil and method for capturing emboli |
| US8945169B2 (en) | 2005-03-15 | 2015-02-03 | Cook Medical Technologies Llc | Embolic protection device |
| US20060229660A1 (en)* | 2005-03-15 | 2006-10-12 | Dharmendra Pal | Embolic protection device |
| US8221446B2 (en) | 2005-03-15 | 2012-07-17 | Cook Medical Technologies | Embolic protection device |
| US20060276805A1 (en)* | 2005-05-03 | 2006-12-07 | Yu Chun H | Vessel recanalizer |
| US7850708B2 (en) | 2005-06-20 | 2010-12-14 | Cook Incorporated | Embolic protection device having a reticulated body with staggered struts |
| US8845677B2 (en) | 2005-06-20 | 2014-09-30 | Cook Medical Technologies Llc | Retrievable device having a reticulation portion with staggered struts |
| US8109962B2 (en) | 2005-06-20 | 2012-02-07 | Cook Medical Technologies Llc | Retrievable device having a reticulation portion with staggered struts |
| US7867247B2 (en) | 2005-07-12 | 2011-01-11 | Cook Incorporated | Methods for embolic protection during treatment of a stenotic lesion in a body vessel |
| US7771452B2 (en) | 2005-07-12 | 2010-08-10 | Cook Incorporated | Embolic protection device with a filter bag that disengages from a basket |
| US7766934B2 (en) | 2005-07-12 | 2010-08-03 | Cook Incorporated | Embolic protection device with an integral basket and bag |
| US8187298B2 (en) | 2005-08-04 | 2012-05-29 | Cook Medical Technologies Llc | Embolic protection device having inflatable frame |
| US8377092B2 (en) | 2005-09-16 | 2013-02-19 | Cook Medical Technologies Llc | Embolic protection device |
| US8632562B2 (en) | 2005-10-03 | 2014-01-21 | Cook Medical Technologies Llc | Embolic protection device |
| US8182508B2 (en) | 2005-10-04 | 2012-05-22 | Cook Medical Technologies Llc | Embolic protection device |
| US8252017B2 (en) | 2005-10-18 | 2012-08-28 | Cook Medical Technologies Llc | Invertible filter for embolic protection |
| US7850623B2 (en) | 2005-10-27 | 2010-12-14 | Boston Scientific Scimed, Inc. | Elongate medical device with continuous reinforcement member |
| US8231551B2 (en) | 2005-10-27 | 2012-07-31 | Boston Scientific Scimed, Inc. | Elongate medical device with continuous reinforcement member |
| US8216269B2 (en) | 2005-11-02 | 2012-07-10 | Cook Medical Technologies Llc | Embolic protection device having reduced profile |
| US8152831B2 (en) | 2005-11-17 | 2012-04-10 | Cook Medical Technologies Llc | Foam embolic protection device |
| US8062321B2 (en) | 2006-01-25 | 2011-11-22 | Pq Bypass, Inc. | Catheter system for connecting adjacent blood vessels |
| US20070203572A1 (en)* | 2006-01-25 | 2007-08-30 | Heuser Richard R | Catheter system with stent apparatus for connecting adjacent blood vessels |
| US7374567B2 (en) | 2006-01-25 | 2008-05-20 | Heuser Richard R | Catheter system for connecting adjacent blood vessels |
| US8500772B2 (en) | 2006-03-20 | 2013-08-06 | Cook Medical Technologies Llc | Distal protection device |
| US20070219579A1 (en)* | 2006-03-20 | 2007-09-20 | Cook Incorporated | Distal protection device |
| US7846175B2 (en) | 2006-04-03 | 2010-12-07 | Medrad, Inc. | Guidewire and collapsable filter system |
| US8551020B2 (en) | 2006-09-13 | 2013-10-08 | Boston Scientific Scimed, Inc. | Crossing guidewire |
| US9907639B2 (en) | 2006-09-19 | 2018-03-06 | Cook Medical Technologies Llc | Apparatus and methods for in situ embolic protection |
| US20080177249A1 (en)* | 2007-01-22 | 2008-07-24 | Heuser Richard R | Catheter introducer system |
| US8012117B2 (en) | 2007-02-06 | 2011-09-06 | Medrad, Inc. | Miniature flexible thrombectomy catheter |
| US20080188831A1 (en)* | 2007-02-06 | 2008-08-07 | Possis Medical, Inc. | Miniature flexible thrombectomy catheter |
| US20080289181A1 (en)* | 2007-02-06 | 2008-11-27 | Possis Medical, Inc. | Method of manufacturing a miniature flexible thrombectomy catheter |
| US7996974B2 (en) | 2007-02-06 | 2011-08-16 | Medrad, Inc. | Method of manufacturing a miniature flexible thrombectomy catheter |
| US9901434B2 (en) | 2007-02-27 | 2018-02-27 | Cook Medical Technologies Llc | Embolic protection device including a Z-stent waist band |
| US20080234813A1 (en)* | 2007-03-20 | 2008-09-25 | Heuser Richard R | Percutaneous Interventional Cardiology System for Treating Valvular Disease |
| US8409114B2 (en) | 2007-08-02 | 2013-04-02 | Boston Scientific Scimed, Inc. | Composite elongate medical device including distal tubular member |
| US8105246B2 (en) | 2007-08-03 | 2012-01-31 | Boston Scientific Scimed, Inc. | Elongate medical device having enhanced torque and methods thereof |
| US8821477B2 (en) | 2007-08-06 | 2014-09-02 | Boston Scientific Scimed, Inc. | Alternative micromachined structures |
| US9808595B2 (en) | 2007-08-07 | 2017-11-07 | Boston Scientific Scimed, Inc | Microfabricated catheter with improved bonding structure |
| US8419748B2 (en) | 2007-09-14 | 2013-04-16 | Cook Medical Technologies Llc | Helical thrombus removal device |
| US8252018B2 (en) | 2007-09-14 | 2012-08-28 | Cook Medical Technologies Llc | Helical embolic protection device |
| US9398946B2 (en) | 2007-09-14 | 2016-07-26 | Cook Medical Technologies Llc | Expandable device for treatment of a stricture in a body vessel |
| US9138307B2 (en) | 2007-09-14 | 2015-09-22 | Cook Medical Technologies Llc | Expandable device for treatment of a stricture in a body vessel |
| US7841994B2 (en) | 2007-11-02 | 2010-11-30 | Boston Scientific Scimed, Inc. | Medical device for crossing an occlusion in a vessel |
| US8376961B2 (en) | 2008-04-07 | 2013-02-19 | Boston Scientific Scimed, Inc. | Micromachined composite guidewire structure with anisotropic bending properties |
| US8535243B2 (en) | 2008-09-10 | 2013-09-17 | Boston Scientific Scimed, Inc. | Medical devices and tapered tubular members for use in medical devices |
| US8795254B2 (en) | 2008-12-10 | 2014-08-05 | Boston Scientific Scimed, Inc. | Medical devices with a slotted tubular member having improved stress distribution |
| US8657849B2 (en) | 2008-12-29 | 2014-02-25 | Cook Medical Technologies Llc | Embolic protection device and method of use |
| US8388644B2 (en) | 2008-12-29 | 2013-03-05 | Cook Medical Technologies Llc | Embolic protection device and method of use |
| US8137293B2 (en) | 2009-11-17 | 2012-03-20 | Boston Scientific Scimed, Inc. | Guidewires including a porous nickel-titanium alloy |
| US8784337B2 (en) | 2010-03-31 | 2014-07-22 | Boston Scientific Scimed, Inc. | Catheter with an improved flexural rigidity profile |
| US8551021B2 (en) | 2010-03-31 | 2013-10-08 | Boston Scientific Scimed, Inc. | Guidewire with an improved flexural rigidity profile |
| US8795202B2 (en) | 2011-02-04 | 2014-08-05 | Boston Scientific Scimed, Inc. | Guidewires and methods for making and using the same |
| US9072874B2 (en) | 2011-05-13 | 2015-07-07 | Boston Scientific Scimed, Inc. | Medical devices with a heat transfer region and a heat sink region and methods for manufacturing medical devices |
| WO2016177323A1 (en)* | 2015-05-04 | 2016-11-10 | 苏州茵络医疗器械有限公司 | Intravascular stent and manufacturing method thereof |
| CN104799983A (en)* | 2015-05-04 | 2015-07-29 | 苏州英络医疗器械有限公司 | Seamless stent and manufacturing method thereof |
| US20180153676A1 (en)* | 2015-05-04 | 2018-06-07 | Suzhou Innomed Medical Device Co., Ltd. | Intravascular stent and manufacturing method thereof |
| US10888411B2 (en)* | 2015-05-04 | 2021-01-12 | Suzhou Innomed Medical Device Co., Ltd. | Intravascular stent and manufacturing method thereof |
| US20180132873A1 (en)* | 2016-11-14 | 2018-05-17 | Covidien Lp | Embolic protection system including multiple filter bodies |
| US10932799B2 (en)* | 2016-11-14 | 2021-03-02 | Covidien Lp | Embolic protection system including multiple filter bodies |
| EP3538020B1 (en)* | 2016-11-14 | 2023-08-30 | Covidien LP | Embolic protection system including multiple filter bodies |
| US20190192177A1 (en)* | 2017-12-22 | 2019-06-27 | Acclarent, Inc. | Reusable navigation guidewire |
| WO2023117159A1 (en)* | 2021-12-21 | 2023-06-29 | Anaconda Biomed, Sl | An intravascular device with an improved attachment of its elements and a method of manufacturing thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003297015A1 (en) | 2004-07-09 |
| US20070100374A1 (en) | 2007-05-03 |
| CA2509676C (en) | 2012-08-14 |
| JP2006509591A (en) | 2006-03-23 |
| WO2004054652A2 (en) | 2004-07-01 |
| EP1578469A2 (en) | 2005-09-28 |
| WO2004054652A3 (en) | 2004-08-12 |
| AU2003297015A8 (en) | 2004-07-09 |
| US8083689B2 (en) | 2011-12-27 |
| CA2509676A1 (en) | 2004-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US8083689B2 (en) | Distal protection guidewire with nitinol core | |
| JP3723451B2 (en) | Radiopaque composite intracorporeal device | |
| JP4939754B2 (en) | Compound medical device with marker | |
| JP2006509591A5 (en) | ||
| EP1578470B1 (en) | Guidewire tip construction | |
| US8337519B2 (en) | Embolic protection filtering device | |
| US8360995B2 (en) | Wire guide | |
| CA2462335C (en) | Composite guidewire | |
| US8257278B2 (en) | Metal composite guide wire | |
| US6652472B2 (en) | Guidewire with smoothly tapered segment | |
| US8226577B2 (en) | Composite guidewire withdrawn and filled tube construction | |
| US20040167441A1 (en) | Composite medical device | |
| WO1999053824A2 (en) | Proximally tapered guidewire tip coil | |
| US6740050B2 (en) | Intracorporeal member with improved transition section |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AS | Assignment | Owner name:SCIMED LIFE SYSTEMS, INC., MINNESOTA Free format text:ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:VRBA, ANTHONY C.;REEL/FRAME:013583/0240 Effective date:20021210 | |
| AS | Assignment | Owner name:BOSTON SCIENTIFIC SCIMED, INC., MINNESOTA Free format text:CHANGE OF NAME;ASSIGNOR:SCIMED LIFE SYSTEMS, INC.;REEL/FRAME:018505/0868 Effective date:20050101 Owner name:BOSTON SCIENTIFIC SCIMED, INC.,MINNESOTA Free format text:CHANGE OF NAME;ASSIGNOR:SCIMED LIFE SYSTEMS, INC.;REEL/FRAME:018505/0868 Effective date:20050101 | |
| STCB | Information on status: application discontinuation | Free format text:ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |