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US20030166126A1 - Secreted and transmembrane polypeptides and nucleic acids encoding the same - Google Patents

Secreted and transmembrane polypeptides and nucleic acids encoding the same

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Publication number
US20030166126A1
US20030166126A1US10/176,754US17675402AUS2003166126A1US 20030166126 A1US20030166126 A1US 20030166126A1US 17675402 AUS17675402 AUS 17675402AUS 2003166126 A1US2003166126 A1US 2003166126A1
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United States
Prior art keywords
seq
acid sequence
shows
sequence
amino acid
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
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US10/176,754
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US7709602B2 (en
Inventor
Kevin Baker
Jian Chen
Luc Desnoyers
Audrey Goddard
Paul Godowski
Austin Gurney
James Pan
Victoria Smith
Colin Watanabe
William Wood
Zemin Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Cargill Inc
MetaMorphix Inc
Original Assignee
Genentech Inc
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Priority claimed from PCT/US1998/019330external-prioritypatent/WO1999014328A2/en
Priority claimed from PCT/US1998/021141external-prioritypatent/WO1999020756A2/en
Priority claimed from US09/168,978external-prioritypatent/US20020086368A1/en
Priority claimed from US09/202,054external-prioritypatent/US7696327B1/en
Priority claimed from US09/187,368external-prioritypatent/US20020052019A1/en
Priority claimed from PCT/US1998/025108external-prioritypatent/WO1999028462A2/en
Priority claimed from PCT/US1999/005028external-prioritypatent/WO1999046281A2/en
Priority claimed from PCT/US1999/010733external-prioritypatent/WO1999060127A2/en
Priority claimed from PCT/US1999/012252external-prioritypatent/WO1999063088A2/en
Priority claimed from PCT/US1999/020111external-prioritypatent/WO2000012708A2/en
Priority claimed from PCT/US1999/021090external-prioritypatent/WO2000015796A2/en
Priority claimed from PCT/US1999/028301external-prioritypatent/WO2000032776A2/en
Priority claimed from PCT/US1999/028551external-prioritypatent/WO2000053750A1/en
Priority claimed from PCT/US1999/031274external-prioritypatent/WO2000053752A2/en
Priority claimed from PCT/US2000/000219external-prioritypatent/WO2000053753A2/en
Priority claimed from PCT/US2000/004342external-prioritypatent/WO2000078961A1/en
Priority claimed from PCT/US2000/004341external-prioritypatent/WO2000053756A2/en
Priority claimed from PCT/US2000/004414external-prioritypatent/WO2001004311A1/en
Priority claimed from PCT/US2000/005004external-prioritypatent/WO2000053757A2/en
Priority claimed from PCT/US2000/005601external-prioritypatent/WO2000056889A2/en
Priority claimed from PCT/US2000/005841external-prioritypatent/WO2000053758A2/en
Priority claimed from PCT/US2000/006884external-prioritypatent/WO2001005972A1/en
Priority claimed from PCT/US2000/008439external-prioritypatent/WO2000073454A1/en
Priority claimed from PCT/US2000/013705external-prioritypatent/WO2000073445A2/en
Priority claimed from PCT/US2000/014042external-prioritypatent/WO2000077037A2/en
Priority claimed from PCT/US2000/014941external-prioritypatent/WO2000073348A2/en
Priority claimed from PCT/US2000/015264external-prioritypatent/WO2000073452A2/en
Priority claimed from PCT/US2000/020710external-prioritypatent/WO2001009327A2/en
Priority claimed from PCT/US2000/023328external-prioritypatent/WO2001016318A2/en
Priority claimed from PCT/US2000/030952external-prioritypatent/WO2001049715A2/en
Priority claimed from PCT/US2000/032678external-prioritypatent/WO2001040466A2/en
Priority claimed from PCT/US2000/034956external-prioritypatent/WO2001046420A2/en
Priority claimed from US09/747,259external-prioritypatent/US6569645B2/en
Priority claimed from PCT/US2001/006520external-prioritypatent/WO2001068848A2/en
Priority claimed from US09/816,744external-prioritypatent/US6579520B2/en
Priority claimed from US09/866,028external-prioritypatent/US6642360B2/en
Priority claimed from PCT/US2001/017800external-prioritypatent/WO2001093983A1/en
Priority claimed from US09/874,503external-prioritypatent/US20020177188A1/en
Priority claimed from PCT/US2001/019692external-prioritypatent/WO2002000690A2/en
Priority claimed from PCT/US2001/021066external-prioritypatent/WO2002008288A2/en
Priority claimed from PCT/US2001/021735external-prioritypatent/WO2002008284A2/en
Priority claimed from US09/908,827external-prioritypatent/US20030054442A1/en
Priority claimed from US09/918,585external-prioritypatent/US20030060406A1/en
Priority claimed from US09/931,836external-prioritypatent/US7435793B2/en
Priority claimed from US09/941,992external-prioritypatent/US20030082546A1/en
Priority claimed from PCT/US2001/027099external-prioritypatent/WO2002024888A2/en
Priority claimed from US09/946,374external-prioritypatent/US20030073129A1/en
Priority claimed from US10/052,586external-prioritypatent/US20020127584A1/en
Application filed by Genentech IncfiledCriticalGenentech Inc
Publication of US20030166126A1publicationCriticalpatent/US20030166126A1/en
Application grantedgrantedCritical
Publication of US7709602B2publicationCriticalpatent/US7709602B2/en
Assigned to METAMORPHIX, INC.reassignmentMETAMORPHIX, INC.ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).Assignors: HOLM, TOM, DENISE, SUE K., CHARTERIS, PAUL, ROSENFELD, DAVID, BATES, STEPHEN
Assigned to CARGILL, INCORPORATED, METAMORPHIX, INC.reassignmentCARGILL, INCORPORATEDNUNC PRO TUNC ASSIGNMENT (SEE DOCUMENT FOR DETAILS).Assignors: METAMORPHIX, INC.
Adjusted expirationlegal-statusCritical
Expired - Lifetimelegal-statusCriticalCurrent

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Abstract

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Description

Claims (24)

What is claimed is:
1. Isolated nucleic acid having at least 80% nucleic acid sequence identity to a nucleotide sequence that encodes an amino acid sequence selected from the group consisting of the amino acid sequence shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), and FIG. 610 (SEQ ID NO: 610).
2. Isolated nucleic acid having at least 80% nucleic acid sequence identity to a nucleotide sequence selected from the group consisting of the nucleotide sequence shown in FIG. 1 (SEQ ID NO: 1), FIG. 3 (SEQ ID NO: 3), FIG. 5 (SEQ ID NO: 5), FIG. 7 (SEQ ID NO: 7), FIG. 9 (SEQ ID NO: 9), FIG. 11 (SEQ ID NO: 11), FIG. 13 (SEQ ID NO: 13), FIG. 15 (SEQ ID NO: 15), FIG. 17 (SEQ ID NO: 17), FIG. 19 (SEQ ID NO: 19), FIG. 21 (SEQ ID NO: 21), FIG. 23 (SEQ ID NO: 23), FIG. 25 (SEQ ID NO: 25), FIG. 27 (SEQ ID NO: 27), FIG. 29 (SEQ ID NO: 29), FIG. 31 (SEQ ID NO: 31), FIG. 33 (SEQ ID NO: 33), FIG. 35 (SEQ ID NO: 35), FIG. 37 (SEQ ID NO: 37), FIG. 39 (SEQ ID NO: 39), FIG. 41 (SEQ ID NO: 41), FIG. 43 (SEQ ID NO: 43), FIG. 45 (SEQ ID NO: 45), FIG. 47 (SEQ ID NO: 47), FIG. 49 (SEQ ID NO: 49), FIG. 51 (SEQ ID NO: 51), FIG. 53 (SEQ ID NO: 53), FIG. 55 (SEQ ID NO: 55), FIG. 57 (SEQ ID NO: 57), FIG. 59 (SEQ ID NO: 59), FIG. 61 (SEQ ID NO: 61), FIG. 63 (SEQ ID NO: 63), FIG. 65 (SEQ ID NO: 65), FIG. 67 (SEQ ID NO: 67), FIG. 69 (SEQ ID NO: 69), FIG. 71 (SEQ ID NO: 71), FIG. 73 (SEQ ID NO: 73), FIGS.75A-75B (SEQ ID NO: 75), FIG. 77 (SEQ ID NO: 77), FIG. 79 (SEQ ID NO: 79), FIG. 81 (SEQ ID NO: 81), FIG. 83 (SEQ ID NO: 83), FIG. 85 (SEQ ID NO: 85), FIG. 87 (SEQ ID NO: 87), FIG. 89 (SEQ ID NO: 89), FIG. 91 (SEQ ID NO: 91), FIG. 93 (SEQ ID NO: 93), FIG. 95 (SEQ ID NO: 95), FIG. 97 (SEQ ID NO: 97), FIG. 99 (SEQ ID NO: 99), FIG. 101 (SEQ ID NO: 101), FIG. 103 (SEQ ID NO: 103), FIG. 105 (SEQ ID NO: 105), FIG. 107 (SEQ ID NO: 107), FIG. 109 (SEQ ID NO: 109), FIG. 111 (SEQ ID NO: 111), FIG. 113 (SEQ ID NO: 113), FIG. 115 (SEQ ID NO: 115), FIG. 117 (SEQ ID NO: 117), FIG. 119 (SEQ ID NO: 119), FIG. 121 (SEQ ID NO: 121), FIG. 123 (SEQ ID NO: 123), FIG. 125 (SEQ ID NO: 125), FIG. 127 (SEQ ID NO: 127), FIG. 129 (SEQ ID NO: 129), FIG. 131 (SEQ ID NO: 131), FIG. 133 (SEQ ID NO: 133), FIG. 135 (SEQ ID NO: 135), FIG. 137 (SEQ ID NO: 137), FIG. 139 (SEQ ID NO: 139), FIG. 141 (SEQ ID NO: 141), FIG. 143 (SEQ ID NO: 143), FIG. 145 (SEQ ID NO: 145), FIG. 147 (SEQ ID NO: 147), FIG. 149 (SEQ ID NO: 149), FIG. 151 (SEQ ID NO: 151), FIG. 153 (SEQ ID NO: 153), FIG. 155 (SEQ ID NO: 155), FIG. 157 (SEQ ID NO: 157), FIG. 159 (SEQ ID NO: 159), FIG. 161 (SEQ ID NO: 161), FIG. 163 (SEQ ID NO: 163), FIG. 165 (SEQ ID NO: 165), FIG. 167 (SEQ ID NO: 167), FIG. 169 (SEQ ID NO: 169), FIG. 171 (SEQ ID NO: 171), FIG. 173 (SEQ ID NO: 173), FIG. 175 (SEQ ID NO: 175), FIG. 177 (SEQ ID NO: 177), FIG. 179 (SEQ ID NO: 179), FIG. 181 (SEQ ID NO: 181), FIG. 183 (SEQ ID NO: 183), FIG. 185 (SEQ ID NO: 185), FIG. 187 (SEQ ID NO: 187), FIG. 189 (SEQ ID NO: 189), FIG. 191 (SEQ ID NO: 191), FIG. 193 (SEQ ID NO: 193), FIG. 195 (SEQ ID NO: 195), FIG. 197 (SEQ ID NO: 197), FIG. 199 (SEQ ID NO: 199), FIG. 201 (SEQ ID NO: 201), FIG. 203 (SEQ ID NO: 203), FIG. 205 (SEQ ID NO: 205), FIG. 207 (SEQ ID NO: 207), FIG. 209 (SEQ ID NO: 209), FIG. 211 (SEQ ID NO: 211), FIG. 213 (SEQ ID NO: 213), FIG. 215 (SEQ ID NO: 215), FIG. 217 (SEQ ID NO: 217), FIG. 219 (SEQ ID NO: 219), FIG. 221 (SEQ ID NO: 221), FIG. 223 (SEQ ID NO: 223), FIG. 225 (SEQ ID NO: 225), FIG. 227 (SEQ ID NO: 227), FIG. 229 (SEQ ID NO: 229), FIG. 231 (SEQ ID NO: 231), FIG. 233 (SEQ ID NO: 233), FIG. 235 (SEQ ID NO: 235), FIG. 237 (SEQ ID NO: 237), FIG. 239 (SEQ ID NO: 239), FIG. 241 (SEQ ID NO: 241), FIG. 243 (SEQ ID NO: 243), FIG. 245 (SEQ ID NO: 245), FIG. 247 (SEQ ID NO: 247), FIG. 249 (SEQ ID NO: 249), FIG. 251 (SEQ ID NO: 251), FIG. 253 (SEQ ID NO: 253), FIG. 255 (SEQ ID NO: 255), FIG. 257 (SEQ ID NO: 257), FIG. 259 (SEQ ID NO: 259), FIG. 261 (SEQ ID NO: 261), FIG. 263 (SEQ ID NO: 263), FIG. 265 (SEQ ID NO: 265), FIG. 267 (SEQ ID NO: 267), FIG. 269 (SEQ ID NO: 269), FIG. 271 (SEQ ID NO: 271), FIG. 273 (SEQ ID NO: 273), FIG. 275 (SEQ ID NO: 275), FIG. 277 (SEQ ID NO: 277), FIG. 279 (SEQ ID NO: 279), FIG. 281 (SEQ ID NO: 281), FIG. 283 (SEQ ID NO: 283), FIG. 285 (SEQ ID NO: 285), FIG. 287 (SEQ ID NO: 287), FIGS.289A-289B (SEQ ID NO: 289), FIG. 291 (SEQ ID NO: 291), FIG. 293 (SEQ ID NO: 293), FIG. 295 (SEQ ID NO: 295), FIG. 297 (SEQ ID NO: 297), FIG. 299 (SEQ ID NO: 299), FIG. 301 (SEQ ID NO: 301), FIG. 303 (SEQ ID NO: 303), FIG. 305 (SEQ ID NO: 305), FIG. 307 (SEQ ID NO: 307), FIG. 309 (SEQ ID NO: 309), FIGS.311A-311B (SEQ ID NO: 311), FIG. 313 (SEQ ID NO: 313), FIG. 315 (SEQ ID NO: 315), FIG. 317 (SEQ ID NO: 317), FIG. 319 (SEQ ID NO: 319), FIG. 321 (SEQ ID NO: 321), FIG. 323 (SEQ ID NO: 323), FIG. 325 (SEQ ID NO: 325), FIG. 327 (SEQ ID NO: 327), FIG. 329 (SEQ ID NO: 329), FIG. 331 (SEQ ID NO: 331), FIG. 333 (SEQ ID NO: 333), FIG. 335 (SEQ ID NO: 335), FIG. 337 (SEQ ID NO: 337), FIG. 339 (SEQ ID NO: 339), FIG. 341 (SEQ ID NO: 341), FIG. 343 (SEQ ID NO: 343), FIG. 345 (SEQ ID NO: 345), FIG. 347 (SEQ ID NO: 347), FIG. 349 (SEQ ID NO: 349), FIGS.351A-351B (SEQ ID NO: 351), FIG. 353 (SEQ ID NO: 353), FIG. 355 (SEQ ID NO: 355), FIG. 357 (SEQ ID NO: 357), FIG. 359 (SEQ ID NO: 359), FIG. 361 (SEQ ID NO: 361), FIG. 363 (SEQ ID NO: 363), FIG. 365 (SEQ ID NO: 365), FIG. 367 (SEQ ID NO: 367), FIG. 369 (SEQ ID NO: 369), FIG. 371 (SEQ ID NO: 371), FIG. 373 (SEQ ID NO: 373), FIG. 375 (SEQ ID NO: 375), FIG. 377 (SEQ ID NO: 377), FIG. 379 (SEQ ID NO: 379), FIG. 381 (SEQ ID NO: 381), FIG. 383 (SEQ ID NO: 383), FIG. 385 (SEQ ID NO: 385), FIG. 387 (SEQ ID NO: 387), FIG. 389 (SEQ ID NO: 389), FIG. 391 (SEQ ID NO: 391), FIG. 393 (SEQ ID NO: 393), FIG. 395 (SEQ ID NO: 395), FIG. 397 (SEQ ID NO: 397), FIG. 399 (SEQ ID NO: 399), FIG. 401 (SEQ ID NO: 401), FIG. 403 (SEQ ID NO: 403), FIG. 405 (SEQ ID NO: 405), FIG. 407 (SEQ ID NO: 407), FIG. 409 (SEQ ID NO: 409), FIG. 411 (SEQ ID NO: 41 1), FIG. 413 (SEQ ID NO: 413), FIG. 415 (SEQ ID NO: 415), FIG. 417 (SEQ ID NO: 417), FIG. 419 (SEQ ID NO: 419), FIG. 421 (SEQ ID NO: 421), FIG. 423 (SEQ ID NO: 423), FIG. 425 (SEQ ID NO: 425), FIG. 427 (SEQ ID NO: 427), FIG.429 (SEQ ID NO: 429), FIG. 431 (SEQ ID NO: 431), FIG. 433 (SEQ ID NO: 433), FIG. 435 (SEQ ID NO: 435), FIG. 437 (SEQ ID NO: 437), FIG. 439 (SEQ ID NO: 439), FIG. 441 (SEQ ID NO: 441), FIG. 443 (SEQ ID NO: 443), FIG. 445 (SEQ ID NO: 445), FIG. 447 (SEQ ID NO: 447), FIG. 449 (SEQ ID NO: 449), FIG. 451 (SEQ ID NO: 451), FIG. 453 (SEQ ID NO: 453), FIG. 455 (SEQ ID NO: 455), FIG. 457 (SEQ ID NO: 457), FIG. 459 (SEQ ID NO: 459), FIG. 461 (SEQ ID NO: 461), FIG. 463 (SEQ ID NO: 463), FIG. 465 (SEQ ID NO: 465), FIG. 467 (SEQ ID NO: 467), FIG. 469 (SEQ ID NO: 469), FIG. 471 (SEQ ID NO: 471), FIG. 473 (SEQ ID NO: 473), FIG. 475 (SEQ ID NO: 475), FIG. 477 (SEQ ID NO: 477), FIG. 479 (SEQ ID NO: 479), FIG. 481 (SEQ ID NO: 481), FIG. 483 (SEQ ID NO: 483), FIG. 485 (SEQ ID NO: 485), FIG. 487 (SEQ ID NO: 487), FIG. 489 (SEQ ID NO: 489), FIG. 491 (SEQ ID NO: 491), FIG. 493 (SEQ ID NO: 493), FIG. 495 (SEQ ID NO: 495), FIG. 497 (SEQ ID NO: 497), FIG. 499 (SEQ ID NO: 499), FIG. 501 (SEQ ID NO: 501), FIG. 503 (SEQ ID NO: 503), FIG. 505 (SEQ ID NO: 505), FIG. 507 (SEQ ID NO: 507), FIG. 509 (SEQ ID NO: 509), FIG. 511 (SEQ ID NO: 511), FIG. 513 (SEQ ID NO: 513), FIG. 515 (SEQ ID NO: 515), FIG. 517 (SEQ ID NO: 517), FIG. 519 (SEQ ID NO: 519), FIG. 521 (SEQ ID NO: 521), FIG. 523 (SEQ ID NO: 523), FIGS.525A-525B (SEQ ID NO: 525), FIG. 527 (SEQ ID NO: 527), FIG. 529 (SEQ ID NO: 529), FIG. 531 (SEQ ID NO: 531), FIG. 533 (SEQ ID NO: 533), FIG. 535 (SEQ ID NO: 535), FIG. 537 (SEQ ID NO: 537), FIG. 539 (SEQ ID NO: 539), FIG. 541 (SEQ ID NO: 541), FIG. 543 (SEQ ID NO: 543), FIG. 545 (SEQ ID NO: 545), FIG. 547 (SEQ ID NO: 547), FIG. 549 (SEQ ID NO: 549), FIG. 551 (SEQ ID NO: 551), FIG. 553 (SEQ ID NO: 553), FIG. 555 (SEQ ID NO: 555), FIG. 557 (SEQ ID NO: 557), FIG. 559 (SEQ ID NO: 559), FIG. 561 (SEQ ID NO: 561), FIG. 563 (SEQ ID NO: 563), FIG. 565 (SEQ ID NO: 565), FIG. 567 (SEQ ID NO: 567), FIG. 569 (SEQ ID NO: 569), FIG. 571 (SEQ ID NO: 571), FIG. 573 (SEQ ID NO: 573), FIG. 575 (SEQ ID NO: 575), FIG. 577 (SEQ ID NO: 577), FIG. 579 (SEQ ID NO: 579), FIG. 581 (SEQ ID NO: 581), FIG. 583 (SEQ ID NO: 583), FIG. 585 (SEQ ID NO: 585), FIG. 587 (SEQ ID NO: 587), FIG. 589 (SEQ ID NO: 589), FIG. 591 (SEQ ID NO: 591), FIG. 593 (SEQ ID NO: 593), FIG. 595 (SEQ ID NO: 595), FIG. 597 (SEQ ID NO: 597), FIG. 599 (SEQ ID NO: 599), FIG. 601 (SEQ ID NO: 601), FIG. 603 (SEQ ID NO: 603), FIG. 605 (SEQ ID NO: 605), FIG. 607 (SEQ ID NO: 607), and FIG. 609 (SEQ ID NO: 609).
3. Isolated nucleic acid having at least 80% nucleic acid sequence identity to a nucleotide sequence selected from the group consisting of the full-length coding sequence of the nucleotide sequence shown in FIG. 1 (SEQ ID NO: 1), FIG. 3 (SEQ ID NO: 3), FIG. 5 (SEQ ID NO: 5), FIG. 7 (SEQ ID NO: 7), FIG. 9 (SEQ ID NO: 9), FIG. 11 (SEQ ID NO: 11), FIG. 13 (SEQ ID NO: 13), FIG. 15 (SEQ ID NO: 15), FIG. 17 (SEQ ID NO: 17), FIG. 19 (SEQ ID NO: 19), FIG. 21 (SEQ ID NO: 21), FIG. 23 (SEQ ID NO: 23), FIG. 25 (SEQ ID NO: 25), FIG. 27 (SEQ ID NO: 27), FIG. 29 (SEQ ID NO: 29), FIG. 31 (SEQ ID NO: 31), FIG. 33 (SEQ ID NO: 33), FIG. 35 (SEQ ID NO: 35), FIG. 37 (SEQ ID NO: 37), FIG. 39 (SEQ ID NO: 39), FIG. 41 (SEQ ID NO: 41), FIG. 43 (SEQ ID NO: 43), FIG. 45 (SEQ ID NO: 45), FIG. 47 (SEQ ID NO: 47), FIG. 49 (SEQ ID NO: 49), FIG. 51 (SEQ ID NO: 51), FIG. 53 (SEQ ID NO: 53), FIG. 55 (SEQ ID NO: 55), FIG. 57 (SEQ ID NO: 57), FIG. 59 (SEQ ID NO: 59), FIG. 61 (SEQ ID NO: 61), FIG. 63 (SEQ ID NO: 63), FIG. 65 (SEQ ID NO: 65), FIG. 67 (SEQ ID NO: 67), FIG. 69 (SEQ ID NO: 69), FIG. 71 (SEQ ID NO: 71), FIG. 73 (SEQ ID NO: 73), FIGS.75A-75B (SEQ ID NO: 75), FIG. 77 (SEQ ID NO: 77), FIG. 79 (SEQ ID NO: 79), FIG. 81 (SEQ ID NO: 81), FIG. 83 (SEQ ID NO: 83), FIG. 85 (SEQ ID NO: 85), FIG. 87 (SEQ ID NO: 87), FIG. 89 (SEQ ID NO: 89), FIG. 91 (SEQ ID NO: 91), FIG. 93 (SEQ ID NO: 93), FIG. 95 (SEQ ID NO: 95), FIG. 97 (SEQ ID NO: 97), FIG. 99 (SEQ ID NO: 99), FIG. 101 (SEQ ID NO: 101), FIG. 103 (SEQ ID NO: 103), FIG. 105 (SEQ ID NO: 105), FIG. 107 (SEQ ID NO: 107), FIG. 109 (SEQ ID NO: 109), FIG. 111 (SEQ ID NO: 111), FIG. 113 (SEQ ID NO: 113), FIG. 115 (SEQ ID NO: 115), FIG. 117 (SEQ ID NO: 117), FIG. 119 (SEQ ID NO: 119), FIG. 121 (SEQ ID NO: 121), FIG. 123 (SEQ ID NO: 123), FIG. 125 (SEQ ID NO: 125), FIG. 127 (SEQ ID NO: 127), FIG. 129 (SEQ ID NO: 129), FIG. 131 (SEQ ID NO: 131), FIG. 133 (SEQ ID NO: 133), FIG. 135 (SEQ ID NO: 135), FIG. 137 (SEQ ID NO: 137), FIG. 139 (SEQ ID NO: 139), FIG. 141 (SEQ ID NO: 141), FIG. 143 (SEQ ID NO: 143), FIG. 145 (SEQ ID NO: 145), FIG. 147 (SEQ ID NO: 147), FIG. 149 (SEQ ID NO: 149), FIG. 151 (SEQ ID NO: 151), FIG. 153 (SEQ ID NO: 153), FIG. 155 (SEQ ID NO: 155), FIG. 157 (SEQ ID NO: 157), FIG. 159 (SEQ ID NO: 159), FIG. 161 (SEQ ID NO: 161), FIG. 163 (SEQ ID NO: 163), FIG. 165 (SEQ ID NO: 165), FIG. 167 (SEQ ID NO: 167), FIG. 169 (SEQ ID NO: 169), FIG. 171 (SEQ ID NO: 171), FIG. 173 (SEQ ID NO: 173), FIG. 175 (SEQ ID NO: 175), FIG. 177 (SEQ ID NO: 177), FIG. 179 (SEQ ID NO: 179), FIG. 181 (SEQ ID NO: 181), FIG. 183 (SEQ ID NO: 183), FIG. 185 (SEQ ID NO: 185), FIG. 187 (SEQ ID NO: 187), FIG. 189 (SEQ ID NO: 189), FIG. 191 (SEQ ID NO: 191), FIG. 193 (SEQ ID NO: 193), FIG. 195 (SEQ ID NO: 195), FIG. 197 (SEQ ID NO: 197), FIG. 199 (SEQ ID NO: 199), FIG. 201 (SEQ ID NO: 201), FIG. 203 (SEQ ID NO: 203), FIG. 205 (SEQ ID NO: 205), FIG. 207 (SEQ ID NO: 207), FIG. 209 (SEQ ID NO: 209), FIG. 211 (SEQ ID NO: 211), FIG. 213 (SEQ ID NO: 213), FIG. 215 (SEQ ID NO: 215), FIG. 217 (SEQ ID NO: 217), FIG. 219 (SEQ ID NO: 219), FIG. 221 (SEQ ID NO: 221), FIG. 223 (SEQ ID NO: 223), FIG. 225 (SEQ ID NO: 225), FIG. 227 (SEQ ID NO: 227), FIG. 229 (SEQ ID NO: 229), FIG. 231 (SEQ ID NO: 231), FIG. 233 (SEQ ID NO: 233), FIG. 235 (SEQ ID NO: 235), FIG. 237 (SEQ ID NO: 237), FIG. 239 (SEQ ID NO: 239), FIG. 241 (SEQ ID NO: 241), FIG. 243 (SEQ ID NO: 243), FIG. 245 (SEQ ID NO: 245), FIG. 247 (SEQ ID NO: 247), FIG. 249 (SEQ ID NO: 249), FIG. 251 (SEQ ID NO: 251), FIG. 253 (SEQ ID NO: 253), FIG. 255 (SEQ ID NO: 255), FIG. 257 (SEQ ID NO: 257), FIG. 259 (SEQ ID NO: 259), FIG. 261 (SEQ ID NO: 261), FIG. 263 (SEQ ID NO: 263), FIG. 265 (SEQ ID NO: 265), FIG. 267 (SEQ ID NO: 267), FIG. 269 (SEQ ID NO: 269), FIG. 271 (SEQ ID NO: 271), FIG. 273 (SEQ ID NO: 273), FIG. 275 (SEQ ID NO: 275), FIG. 277 (SEQ ID NO: 277), FIG. 279 (SEQ ID NO: 279), FIG. 281 (SEQ ID NO: 281), FIG. 283 (SEQ ID NO: 283), FIG. 285 (SEQ ID NO: 285), FIG. 287 (SEQ ID NO: 287), FIGS.289A-289B (SEQ ID NO: 289), FIG. 291 (SEQ ID NO: 291), FIG. 293 (SEQ ID NO: 293), FIG. 295 (SEQ ID NO: 295), FIG. 297 (SEQ ID NO: 297), FIG. 299 (SEQ ID NO: 299), FIG. 301 (SEQ ID NO: 301), FIG. 303 (SEQ ID NO: 303), FIG. 305 (SEQ ID NO: 305), FIG. 307 (SEQ ID NO: 307), FIG. 309 (SEQ ID NO: 309), FIGS.311A-311B (SEQ ID NO: 311), FIG. 313 (SEQ ID NO: 313), FIG. 315 (SEQ ID NO: 315), FIG. 317 (SEQ ID NO: 317), FIG. 319 (SEQ ID NO: 319), FIG. 321 (SEQ ID NO: 321), FIG. 323 (SEQ ID NO: 323), FIG. 325 (SEQ ID NO: 325), FIG. 327 (SEQ ID NO: 327), FIG. 329 (SEQ ID NO: 329), FIG. 331 (SEQ ID NO: 331), FIG. 333 (SEQ ID NO: 333), FIG. 335 (SEQ ID NO: 335), FIG. 337 (SEQ ID NO: 337), FIG. 339 (SEQ ID NO: 339), FIG. 341 (SEQ ID NO: 341), FIG. 343 (SEQ ID NO: 343), FIG. 345 (SEQ ID NO: 345), FIG. 347 (SEQ ID NO: 347), FIG. 349 (SEQ ID NO: 349), FIGS.351A-351B (SEQ ID NO: 351), FIG. 353 (SEQ ID NO: 353), FIG. 355 (SEQ ID NO: 355), FIG. 357 (SEQ ID NO: 357), FIG. 359 (SEQ ID NO: 359), FIG. 361 (SEQ ID NO: 361), FIG. 363 (SEQ ID NO: 363), FIG. 365 (SEQ ID NO: 365), FIG. 367 (SEQ ID NO: 367), FIG. 369 (SEQ ID NO: 369), FIG. 371 (SEQ ID NO: 371), FIG. 373 (SEQ ID NO: 373), FIG. 375 (SEQ ID NO: 375), FIG. 377 (SEQ ID NO: 377), FIG. 379 (SEQ ID NO: 379), FIG. 381 (SEQ ID NO: 381), FIG. 383 (SEQ ID NO: 383), FIG. 385 (SEQ ID NO: 385), FIG. 387 (SEQ ID NO: 387), FIG. 389 (SEQ ID NO: 389), FIG. 391 (SEQ ID NO: 391), FIG. 393 (SEQ ID NO: 393), FIG. 395 (SEQ ID NO: 395), FIG. 397 (SEQ ID NO: 397), FIG. 399 (SEQ ID NO: 399), FIG. 401 (SEQ ID NO: 401), FIG. 403 (SEQ ID NO: 403), FIG. 405 (SEQ ID NO: 405), FIG. 407 (SEQ ID NO: 407), FIG. 409 (SEQ ID NO: 409), FIG. 411 (SEQ ID NO: 411), FIG. 413 (SEQ ID NO: 413), FIG. 415 (SEQ ID NO: 415), FIG. 417 (SEQ ID NO: 417), FIG. 419 (SEQ ID NO: 419), FIG. 421 (SEQ ID NO: 421), FIG. 423 (SEQ ID NO: 423), FIG. 425 (SEQ ID NO: 425), FIG. 427 (SEQ ID NO: 427), FIG. 429 (SEQ ID NO: 429), FIG. 431 (SEQ ID NO: 431), FIG. 433 (SEQ ID NO: 433), FIG. 435 (SEQ ID NO: 435), FIG. 437 (SEQ ID NO: 437), FIG. 439 (SEQ ID NO: 439), FIG. 441 (SEQ ID NO: 441), FIG. 443 (SEQ ID NO: 443), FIG. 445 (SEQ ID NO: 445), FIG. 447 (SEQ ID NO: 447), FIG. 449 (SEQ ID NO: 449), FIG. 451 (SEQ ID NO: 451), FIG. 453 (SEQ ID NO: 453), FIG. 455 (SEQ ID NO: 455), FIG. 457 (SEQ ID NO: 457), FIG. 459 (SEQ ID NO: 459), FIG. 461 (SEQ ID NO: 461), FIG. 463 (SEQ ID NO: 463), FIG. 465 (SEQ ID NO: 465), FIG. 467 (SEQ ID NO: 467), FIG. 469 (SEQ ID NO: 469), FIG. 471 (SEQ ID NO: 471), FIG. 473 (SEQ ID NO: 473), FIG. 475 (SEQ ID NO: 475), FIG. 477 (SEQ ID NO: 477), FIG. 479 (SEQ ID NO: 479), FIG. 481 (SEQ ID NO: 481), FIG. 483 (SEQ ID NO: 483), FIG. 485 (SEQ ID NO: 485), FIG. 487 (SEQ ID NO: 487), FIG. 489 (SEQ ID NO: 489), FIG. 491 (SEQ ID NO: 491), FIG. 493 (SEQ ID NO: 493), FIG. 495 (SEQ ID NO: 495), FIG. 497 (SEQ ID NO: 497), FIG. 499 (SEQ ID NO: 499), FIG. 501 (SEQ ID NO: 501), FIG. 503 (SEQ ID NO: 503), FIG. 505 (SEQ ID NO: 505), FIG. 507 (SEQ ID NO: 507), FIG. 509 (SEQ ID NO: 509), FIG. 511 (SEQ ID NO: 511), FIG. 513 (SEQ ID NO: 513), FIG. 515 (SEQ ID NO: 515), FIG. 517 (SEQ ID NO: 517), FIG. 519 (SEQ ID NO: 519), FIG. 521 (SEQ ID NO: 521), FIG. 523 (SEQ ID NO: 523), FIGS.525A-525B (SEQ ID NO: 525), FIG. 527 (SEQ ID NO: 527), FIG. 529 (SEQ ID NO: 529), FIG. 531 (SEQ ID NO: 531), FIG. 533 (SEQ ID NO: 533), FIG. 535 (SEQ ID NO: 535), FIG. 537 (SEQ ID NO: 537), FIG. 539 (SEQ ID NO: 539), FIG. 541 (SEQ ID NO: 541), FIG. 543 (SEQ ID NO: 543), FIG. 545 (SEQ ID NO: 545), FIG. 547 (SEQ ID NO: 547), FIG. 549 (SEQ ID NO: 549), FIG. 551 (SEQ ID NO: 551), FIG. 553 (SEQ ID NO: 553), FIG. 555 (SEQ ID NO: 555), FIG. 557 (SEQ ID NO: 557), FIG. 559 (SEQ ID NO: 559), FIG. 561 (SEQ ID NO: 561), FIG. 563 (SEQ ID NO: 563), FIG. 565 (SEQ ID NO: 565), FIG. 567 (SEQ ID NO: 567), FIG. 569 (SEQ ID NO: 569), FIG. 571 (SEQ ID NO: 571), FIG. 573 (SEQ ID NO: 573), FIG. 575 (SEQ ID NO: 575), FIG. 577 (SEQ ID NO: 577), FIG. 579 (SEQ ID NO: 579), FIG. 581 (SEQ ID NO: 581), FIG. 583 (SEQ ID NO: 583), FIG. 585 (SEQ ID NO: 585), FIG. 587 (SEQ ID NO: 587), FIG. 589 (SEQ ID NO: 589), FIG. 591 (SEQ ID NO: 591), FIG. 593 (SEQ ID NO: 593), FIG. 595 (SEQ ID NO: 595), FIG. 597 (SEQ ID NO: 597), FIG. 599 (SEQ ID NO: 599), FIG. 601 (SEQ ID NO: 601), FIG. 603 (SEQ ID NO: 603), FIG. 605 (SEQ ID NO: 605), FIG. 607 (SEQ ID NO: 607), and FIG. 609 (SEQ ID NO: 609).
4. Isolated nucleic acid having at least 80% nucleic acid sequence identity to the full-length coding sequence of the DNA deposited under any ATCC accession number shown in Table 7.
5. A vector comprising the nucleic acid ofclaim 1.
6. A host cell comprising the vector ofclaim 5.
7. The host cell ofclaim 6, wherein said cell is a CHO cell.
8. The host cell ofclaim 6, wherein said cell is anE. coli.
9. The host cell ofclaim 6, wherein said cell is a yeast cell.
10. A process for producing a PRO polypeptide comprising culturing the host cell ofclaim 6 under conditions suitable for expression of said PRO polypeptide and recovering said PRO polypeptide from the cell culture.
11. An isolated polypeptide having at least 80% amino acid sequence identity to an amino acid sequence selected from the group consisting of the amino acid sequence shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), and FIG. 610 (SEQ ID NO: 610).
12. An isolated polypeptide having at least 80% amino acid sequence identity to an amino acid sequence encoded by the full-length coding sequence of the DNA deposited under any ATCC accession number shown in Table 7.
13. A chimeric molecule comprising a polypeptide according toclaim 11 fused to a heterologous amino acid sequence.
14. The chimeric molecule ofclaim 13, wherein said heterologous amino acid sequence is an epitope tag sequence.
15. The chimeric molecule ofclaim 13, wherein said heterologous amino acid sequence is a Fc region of an immunoglobulin.
16. An antibody which specifically binds to a polypeptide according toclaim 11.
17. The antibody ofclaim 16, wherein said antibody is a monoclonal antibody, a humanized antibody or a single-chain antibody.
18. Isolated nucleic acid having at least 80% nucleic acid sequence identity to:
(a) a nucleotide sequence encoding the polypeptide shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), lacking its associated signal peptide;
(b) a nucleotide sequence encoding an extracellular domain of the polypeptide shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG.94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 360 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), with its associated signal peptide; or
(c) a nucleotide sequence encoding an extracellular domain of the polypeptide shown in FIG.2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), lacking its associated signal peptide.
19. An isolated polypeptide having at least 80% amino acid sequence identity to:
(a) an amino acid sequence of the polypeptide shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), lacking its associated signal peptide;
(b) an amino acid sequence of an extracellular domain of the polypeptide shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), with its associated signal peptide; or
(c) an amino acid sequence of an extracellular domain of the polypeptide shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76 ), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 8 8), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 10), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), lacking its associated signal peptide.
20. A method for stimulating the release of TNF-α from human blood, said method comprising contacting said blood with a PRO1079, PRO827, PRO791, PRO1131, PRO1316, PRO1183, PRO1343, PRO1760, PRO1567 or PRO4333 polypeptide, wherein the release of TNF-α from said blood is stimulated.
21. A method for stimulating the proliferation or differentiation of chondrocyte cells, said method comprising contacting said cells with a PRO6029 polypeptide, wherein the proliferation or differentiation of said cells is stimulated.
22. A method for detecting the presence of tumor in an mammal, said method comprising comparing the level of expression of any PRO polypeptide shown in Table 8 in (a) a test sample of cells taken from said mammal and (b) a control sample of normal cells of the same cell type, wherein a higher level of expression of said PRO polypeptide in the test sample as compared to the control sample is indicative of the presence of tumor in said mammal.
23. The method ofclaim 22, wherein said tumor is adrenal tumor, lung tumor, colon tumor, breast tumor, prostate tumor, rectal tumor, cervical tumor or liver tumor.
24. An oligonucleotide probe derived from any of the nucleotide sequences shown in the accompanying figures.
US10/176,7541997-09-182002-06-20PRO1078 polypeptidesExpired - LifetimeUS7709602B2 (en)

Applications Claiming Priority (134)

Application NumberPriority DateFiling DateTitle
US5926397P1997-09-181997-09-18
US5926697P1997-09-181997-09-18
US6225097P1997-10-171997-10-17
US6348697P1997-10-211997-10-21
US6312097P1997-10-241997-10-24
US6312197P1997-10-241997-10-24
US6354497P1997-10-281997-10-28
US6354097P1997-10-281997-10-28
US6354197P1997-10-281997-10-28
US6356497P1997-10-281997-10-28
US6373497P1997-10-291997-10-29
US6410397P1997-10-311997-10-31
US6387097P1997-10-311997-10-31
US6531197P1997-11-131997-11-13
US6612097P1997-11-211997-11-21
US6677297P1997-11-241997-11-24
US6646697P1997-11-241997-11-24
US6933597P1997-12-111997-12-11
US6942597P1997-12-121997-12-12
US6987097P1997-12-171997-12-17
US6801797P1997-12-181997-12-18
US7745098P1998-03-101998-03-10
US7763298P1998-03-111998-03-11
US7764998P1998-03-111998-03-11
US7888698P1998-03-201998-03-20
US7893998P1998-03-201998-03-20
US7966498P1998-03-271998-03-27
US7978698P1998-03-271998-03-27
US8010798P1998-03-311998-03-31
US8019498P1998-03-311998-03-31
US8032798P1998-04-011998-04-01
US8033398P1998-04-011998-04-01
US8107098P1998-04-081998-04-08
US8104998P1998-04-081998-04-08
US8119598P1998-04-091998-04-09
US10541398A1998-06-261998-06-26
WOPCT/US98/193301998-09-16
PCT/US1998/019330WO1999014328A2 (en)1997-09-171998-09-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US98/211411998-10-07
PCT/US1998/021141WO1999020756A2 (en)1997-10-171998-10-07Human toll homologues
US09/168,978US20020086368A1 (en)1997-10-171998-10-07Human toll homologues
US09/202,054US7696327B1 (en)1997-10-171998-10-07Antibodies to human Toll homologues
US09/187,368US20020052019A1 (en)1997-11-131998-11-06Human toll homologue
WOPCT/US98/251081998-12-01
PCT/US1998/025108WO1999028462A2 (en)1997-12-031998-12-01Polypeptides and nucleic acids encoding the same
US25431199A1999-03-031999-03-03
WOPCT/US99/050281999-03-08
PCT/US1999/005028WO1999046281A2 (en)1998-03-101999-03-08Novel polypeptides and nucleic acids encoding the same
US31183299A1999-05-141999-05-14
WOPCT/US99/107331999-05-14
PCT/US1999/010733WO1999060127A2 (en)1998-05-151999-05-14Il-17 homologous polypeptides and therapeutic uses thereof
WOPCT/US99/122521999-06-02
PCT/US1999/012252WO1999063088A2 (en)1998-06-021999-06-02Membrane-bound proteins and nucleic acids encoding the same
US38013999A1999-08-251999-08-25
US38013899A1999-08-251999-08-25
US38014299A1999-08-251999-08-25
WOPCT/US99/201111999-09-01
PCT/US1999/020111WO2000012708A2 (en)1998-09-011999-09-01Further pro polypeptides and sequences thereof
PCT/US1999/021090WO2000015796A2 (en)1998-09-161999-09-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US99/210901999-09-15
US40329799A1999-10-181999-10-18
US40384499A1999-10-271999-10-27
PCT/US1999/028301WO2000032776A2 (en)1998-12-011999-12-01Secreted amd transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US99/283011999-12-01
PCT/US1999/028551WO2000053750A1 (en)1999-03-081999-12-02Compositions and methods for the treatment of tumors
WOPCT/US99/285511999-12-02
WOPCT/US99/312741999-12-30
PCT/US1999/031274WO2000053752A2 (en)1999-03-081999-12-30Promotion or inhibition of angiogenesis and cardiovascularization
WOPCT/US00/002192000-01-05
PCT/US2000/000219WO2000053753A2 (en)1999-03-082000-01-05Promotion or inhibition of angiogenesis and cardiovascularization
PCT/US2000/004342WO2000078961A1 (en)1999-06-232000-02-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US00/043422000-02-18
PCT/US2000/004341WO2000053756A2 (en)1999-03-082000-02-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US00/043412000-02-18
PCT/US2000/004414WO2001004311A1 (en)1999-07-072000-02-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US00/044142000-02-22
WOPCT/US00/050042000-02-24
PCT/US2000/005004WO2000053757A2 (en)1999-03-082000-02-24Promotion or inhibition of angiogenesis and cardiovascularization
WOPCT/US00/056012000-03-01
PCT/US2000/005601WO2000056889A2 (en)1999-03-232000-03-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US00/058412000-03-02
PCT/US2000/005841WO2000053758A2 (en)1999-03-082000-03-02Compositions and methods for the treatment of immune related diseases
WOPCT/US00/068842000-03-15
PCT/US2000/006884WO2001005972A1 (en)1999-07-202000-03-15Compositions and methods for the treatment of immune related diseases
WOPCT/US00/084392000-03-30
PCT/US2000/008439WO2000073454A1 (en)1999-06-022000-03-30Secreted and transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US00/137052000-05-17
PCT/US2000/013705WO2000073445A2 (en)1999-06-022000-05-17Interleukin-1-receptor associated kinase-3 (irak3)
PCT/US2000/014042WO2000077037A2 (en)1999-06-152000-05-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US00/140422000-05-22
WOPCT/US00/149412000-05-30
PCT/US2000/014941WO2000073348A2 (en)1999-06-022000-05-30Methods and compositions for inhibiting neoplastic cell growth
PCT/US2000/015264WO2000073452A2 (en)1999-06-022000-06-02Compositions and methods for the treatment of immune related diseases
WOPCT/US00/152642000-06-02
PCT/US2000/020710WO2001009327A2 (en)1999-07-282000-07-28Method of preventing the injury or death of retinal cells and treating ocular diseases
WOPCT/US00/207102000-07-28
US64484800A2000-08-222000-08-22
WOPCT/US00/233282000-08-24
PCT/US2000/023328WO2001016318A2 (en)1999-09-012000-08-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US66461000A2000-09-182000-09-18
US66535000A2000-09-182000-09-18
US70923800A2000-11-082000-11-08
WOPCT/US00/309522000-11-08
PCT/US2000/030952WO2001049715A2 (en)2000-01-062000-11-08Methods and compositions for inhibiting neoplastic cell growth
PCT/US2000/032678WO2001040466A2 (en)1999-12-012000-12-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US00/326782000-12-01
PCT/US2000/034956WO2001046420A2 (en)1999-12-232000-12-20Il-17 and il-17r homologous polypeptides and therapeutic uses thereof
US09/747,259US6569645B2 (en)1999-05-142000-12-20IL-17 homologous polypeptides and therapeutic uses thereof
WOPCT/US00/349562000-12-20
WOPCT/US01/065202001-02-28
PCT/US2001/006520WO2001068848A2 (en)2000-03-012001-02-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/816,744US6579520B2 (en)1998-05-152001-03-22IL-17 related mammalian cytokine polypeptides (IL-17E)
US09/854,208US7217412B2 (en)1998-05-152001-05-10IL-17C related mammalian cytokine polypeptides
US09/854,280US7115398B2 (en)1998-05-152001-05-10IL-17 homologous polypeptides and therapeutic uses thereof
US09/866,028US6642360B2 (en)1997-12-032001-05-25Secreted polypeptides that stimulate release of proteoglycans from cartilage
WOPCT/US01/178002001-06-01
PCT/US2001/017800WO2001093983A1 (en)2000-06-022001-06-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/874,503US20020177188A1 (en)1998-05-152001-06-05IL-17 homologous polypeptides and therapeutic uses thereof
WOPCT/US01/196922001-06-20
PCT/US2001/019692WO2002000690A2 (en)2000-06-232001-06-20Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
WOPCT/US01/210662001-06-29
PCT/US2001/021066WO2002008288A2 (en)2000-07-202001-06-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/021735WO2002008284A2 (en)2000-07-202001-07-09Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
WOPCT/US01/217352001-07-09
US09/908,827US20030054442A1 (en)1998-05-152001-07-18IL-17 homologous polypeptides and therapeutic uses thereof
US09/918,585US20030060406A1 (en)1997-10-172001-07-30Secreted and transmembrane polypeptides and nucleic acids encoding the same
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US92940401A2001-08-132001-08-13
US09/931,836US7435793B2 (en)1998-05-152001-08-16Peptides that induce chondrocyte redifferentiation
US09/941,992US20030082546A1 (en)1996-11-062001-08-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
WOPCT/US01/270992001-08-29
PCT/US2001/027099WO2002024888A2 (en)2000-09-012001-08-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/946,374US20030073129A1 (en)1998-09-012001-09-04Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/052,586US20020127584A1 (en)1997-09-182002-01-15Secreted and transmembrane polypeptides and nucleic acids encoding the same

Related Parent Applications (30)

Application NumberTitlePriority DateFiling Date
US09380137Continuation
US10541398AContinuation1996-11-061998-06-26
US09/202,054ContinuationUS7696327B1 (en)1996-11-061998-10-07Antibodies to human Toll homologues
US09/168,978ContinuationUS20020086368A1 (en)1996-11-061998-10-07Human toll homologues
US09/187,368ContinuationUS20020052019A1 (en)1996-11-061998-11-06Human toll homologue
US25431199AContinuation1996-11-061999-03-03
US31183299AContinuation1997-09-151999-05-14
US38014299AContinuation1997-09-151999-08-25
US38013999AContinuation1996-11-061999-08-25
US38013899AContinuation1996-11-061999-08-25
US40329799AContinuation1997-08-261999-10-18
US40384499AContinuation1997-09-181999-10-27
US64484800AContinuation1997-09-152000-08-22
US66535000AContinuation1994-09-082000-09-18
US66461000AContinuation1996-11-062000-09-18
US70923800AContinuation1996-11-062000-11-08
US09/747,259ContinuationUS6569645B2 (en)1997-03-312000-12-20IL-17 homologous polypeptides and therapeutic uses thereof
US09/816,744ContinuationUS6579520B2 (en)1997-03-312001-03-22IL-17 related mammalian cytokine polypeptides (IL-17E)
US09/854,208ContinuationUS7217412B2 (en)1997-03-312001-05-10IL-17C related mammalian cytokine polypeptides
US09/854,280ContinuationUS7115398B2 (en)1997-03-312001-05-10IL-17 homologous polypeptides and therapeutic uses thereof
US09/866,028ContinuationUS6642360B2 (en)1996-11-062001-05-25Secreted polypeptides that stimulate release of proteoglycans from cartilage
US09/874,503ContinuationUS20020177188A1 (en)1997-03-312001-06-05IL-17 homologous polypeptides and therapeutic uses thereof
US09/908,827ContinuationUS20030054442A1 (en)1997-03-312001-07-18IL-17 homologous polypeptides and therapeutic uses thereof
US09/918,585ContinuationUS20030060406A1 (en)1997-09-152001-07-30Secreted and transmembrane polypeptides and nucleic acids encoding the same
US92441901AContinuation1997-03-312001-08-06
US92940401AContinuation1997-09-152001-08-13
US09/931,836ContinuationUS7435793B2 (en)1997-03-312001-08-16Peptides that induce chondrocyte redifferentiation
US09/941,992ContinuationUS20030082546A1 (en)1996-11-062001-08-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/946,374ContinuationUS20030073129A1 (en)1997-09-152001-09-04Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/052,586ContinuationUS20020127584A1 (en)1997-09-152002-01-15Secreted and transmembrane polypeptides and nucleic acids encoding the same

Publications (2)

Publication NumberPublication Date
US20030166126A1true US20030166126A1 (en)2003-09-04
US7709602B2 US7709602B2 (en)2010-05-04

Family

ID=56290294

Family Applications (219)

Application NumberTitlePriority DateFiling Date
US10/173,705AbandonedUS20030032103A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,702AbandonedUS20030170793A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,703AbandonedUS20030170794A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,701AbandonedUS20030104538A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,697AbandonedUS20030032102A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,693AbandonedUS20030073169A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,699AbandonedUS20030166109A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,696AbandonedUS20030082767A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,695AbandonedUS20030032101A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,690AbandonedUS20030166105A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,691AbandonedUS20030166106A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,706AbandonedUS20030022293A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,707AbandonedUS20030166110A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,704AbandonedUS20030170795A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,694AbandonedUS20030166107A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,692AbandonedUS20030166188A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,700AbandonedUS20030027262A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,698AbandonedUS20030166108A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,582AbandonedUS20030027265A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,578AbandonedUS20030073170A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,591AbandonedUS20030166115A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,587AbandonedUS20030166113A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,583Expired - Fee RelatedUS7211645B2 (en)1997-09-182002-06-18PRO268 polypeptides
US10/174,574AbandonedUS20030170796A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,585AbandonedUS20030032105A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,581Expired - LifetimeUS7153939B2 (en)1997-09-182002-06-18PRO354 antibodies
US10/174,569AbandonedUS20030166111A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,586AbandonedUS20030032106A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,572AbandonedUS20030027263A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,588AbandonedUS20030027266A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,570AbandonedUS20030211572A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,579AbandonedUS20030027264A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,576Expired - Fee RelatedUS7125962B2 (en)1997-09-182002-06-18Anti-Pro268 antibodies
US10/175,753AbandonedUS20030077732A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,745AbandonedUS20030166120A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,750AbandonedUS20030073172A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,748AbandonedUS20030166121A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,739AbandonedUS20030027267A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,751AbandonedUS20030166122A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,747AbandonedUS20030032107A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,743AbandonedUS20030027269A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,752AbandonedUS20030022295A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,741AbandonedUS20030073171A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,735AbandonedUS20030082715A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,738AbandonedUS20030022294A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,742AbandonedUS20030166118A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,754AbandonedUS20030166123A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,736AbandonedUS20030166117A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,744AbandonedUS20030166119A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,993AbandonedUS20030027280A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,921AbandonedUS20030027276A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,490AbandonedUS20030170798A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,981AbandonedUS20030170800A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,920AbandonedUS20030166129A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,753AbandonedUS20030044917A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,918Expired - LifetimeUS7495083B2 (en)1997-09-182002-06-20PRO940 antibodies
US10/176,989AbandonedUS20030170803A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,487AbandonedUS20030032110A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,917AbandonedUS20030044918A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,491AbandonedUS20030087373A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,747AbandonedUS20030027273A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,493AbandonedUS20030032111A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,757Expired - Fee RelatedUS7317082B2 (en)1997-09-182002-06-20PRO1018 polypeptides
US10/176,919AbandonedUS20030032114A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,754Expired - LifetimeUS7709602B2 (en)1997-09-182002-06-20PRO1078 polypeptides
US10/176,484AbandonedUS20030059876A9 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,759AbandonedUS20030166128A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,988AbandonedUS20030170802A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,914AbandonedUS20030017543A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,485AbandonedUS20030032109A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,749AbandonedUS20030017542A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,746AbandonedUS20030068680A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,755AbandonedUS20030166127A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,924AbandonedUS20030166131A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,486Expired - LifetimeUS7354999B2 (en)1997-09-182002-06-21PRO1481 polypeptides
US10/176,925AbandonedUS20030032115A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,982AbandonedUS20030044919A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,481AbandonedUS20030032108A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,985AbandonedUS20030027277A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,750AbandonedUS20030027274A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,488AbandonedUS20030027271A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,916AbandonedUS20030040056A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,923AbandonedUS20030068681A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,991AbandonedUS20030027324A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,987AbandonedUS20030027278A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,489AbandonedUS20030166125A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,986AbandonedUS20030073173A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,915AbandonedUS20030017544A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,983AbandonedUS20030170801A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,979AbandonedUS20030087374A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,752AbandonedUS20030170799A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,748AbandonedUS20030040055A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,756AbandonedUS20030032112A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,922AbandonedUS20030166130A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,480AbandonedUS20030166124A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,751AbandonedUS20030036117A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,978AbandonedUS20030032116A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,515AbandonedUS20030166135A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,510AbandonedUS20030032117A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,525AbandonedUS20030040060A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,514AbandonedUS20030044922A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,518AbandonedUS20030104540A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,512AbandonedUS20030166134A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,519Expired - Fee RelatedUS7339024B2 (en)1997-09-182002-06-24PRO1772 polypeptides
US10/179,513AbandonedUS20030044921A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,516AbandonedUS20030040058A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,522AbandonedUS20030044923A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,520AbandonedUS20030096353A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,517AbandonedUS20030170805A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,511AbandonedUS20030104539A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,508AbandonedUS20030166133A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,521AbandonedUS20030170806A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,523AbandonedUS20030215909A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,509AbandonedUS20030207392A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,506AbandonedUS20030044920A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,553Expired - LifetimeUS7365156B2 (en)1997-09-182002-06-25PRO1316 polypeptides
US10/180,552Expired - Fee RelatedUS7348415B2 (en)1997-09-182002-06-25PRO1316 antibodies
US10/180,550AbandonedUS20030064440A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,549AbandonedUS20030032122A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,559AbandonedUS20030032124A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,557AbandonedUS20030022301A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,551AbandonedUS20030036123A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,548Expired - Fee RelatedUS7696319B2 (en)1997-09-182002-06-25PRO1772 antibodies
US10/180,546AbandonedUS20030032120A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,543AbandonedUS20030032118A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,545AbandonedUS20030040062A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,547AbandonedUS20030032121A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,541AbandonedUS20030036120A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,560AbandonedUS20030044925A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,556Expired - LifetimeUS7355000B2 (en)1997-09-182002-06-25PRO1380 polypeptides
US10/180,555AbandonedUS20030032123A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,018AbandonedUS20030104541A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,006Expired - LifetimeUS7297776B2 (en)1997-09-182002-06-26PRO1374 antibodies
US10/181,000Expired - LifetimeUS7319137B2 (en)1997-09-182002-06-26PRO1339 polypeptides
US10/183,014AbandonedUS20030064441A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,019Expired - LifetimeUS7425605B2 (en)1997-09-182002-06-26PRO1486 polypeptides
US10/183,005Expired - LifetimeUS7317093B2 (en)1997-09-182002-06-26PRO1339 antibodies
US10/183,017AbandonedUS20030040065A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,009Expired - LifetimeUS7339034B2 (en)1997-09-182002-06-26PRO1305 antibodies
US10/183,012Expired - LifetimeUS7718770B2 (en)1997-09-182002-06-26PRO1305-polypeptides
US10/183,016AbandonedUS20030082717A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,003AbandonedUS20030082716A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,013Expired - LifetimeUS7309769B2 (en)1997-09-182002-06-26PRO1487 polypeptides
US10/183,002AbandonedUS20030054454A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,010AbandonedUS20030032126A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,008AbandonedUS20030040064A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,015AbandonedUS20030044926A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,999Expired - LifetimeUS7297767B2 (en)1997-09-182002-06-26PRO1374 polypeptides
US10/180,998Expired - Fee RelatedUS7087421B2 (en)1997-09-182002-06-26Pro1278 polypeptides
US10/184,630Expired - LifetimeUS7304143B2 (en)1997-09-182002-06-27PRO1571 antibodies
US10/184,654Expired - LifetimeUS7378486B2 (en)1997-09-182002-06-27PRO1482 antibodies
US10/184,633AbandonedUS20030068683A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,615AbandonedUS20030044927A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,638AbandonedUS20030054456A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,619AbandonedUS20030049738A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,627Expired - LifetimeUS7282569B2 (en)1997-09-182002-06-27PRO1508 antibodies
US10/184,652AbandonedUS20030032134A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,642Expired - Fee RelatedUS7332573B2 (en)1997-09-182002-06-27PRO1571 polypeptides
US10/184,627GrantedUS20030040070A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,631AbandonedUS20030036134A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,613AbandonedUS20030119105A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,628Expired - LifetimeUS7309770B2 (en)1997-09-182002-06-27PRO1757 polypeptides
US10/184,612AbandonedUS20030036127A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,618Expired - LifetimeUS7393917B2 (en)1997-09-182002-06-27PRO1482 polypeptides
US10/184,641AbandonedUS20030073174A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,616AbandonedUS20030036128A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,651Expired - LifetimeUS7291704B2 (en)1997-09-182002-06-27PRO1758 polypeptides
US10/184,630GrantedUS20030036133A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,614AbandonedUS20030032128A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,632AbandonedUS20030036135A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,624AbandonedUS20030104542A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,646AbandonedUS20030032132A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,647AbandonedUS20030032133A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,637AbandonedUS20030032131A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,655AbandonedUS20030040073A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,620AbandonedUS20030044928A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,643AbandonedUS20030044929A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,644AbandonedUS20030044930A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,617AbandonedUS20030036129A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,623AbandonedUS20030032129A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,626AbandonedUS20030040069A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,629AbandonedUS20030036132A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,635AbandonedUS20030032130A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,636AbandonedUS20030036136A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,650AbandonedUS20030036138A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,625AbandonedUS20030040068A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,656AbandonedUS20030044931A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,657AbandonedUS20030104543A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,622AbandonedUS20030036130A1 (en)1997-09-182002-06-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,598AbandonedUS20030036142A1 (en)1997-09-182002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,601Expired - LifetimeUS7291705B2 (en)1997-09-182002-07-01PRO19645 polypeptides
US10/187,886Expired - LifetimeUS7291708B2 (en)1997-09-182002-07-01PRO1785 polypeptides
US10/187,597AbandonedUS20030036141A1 (en)1997-09-182002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,747Expired - LifetimeUS7291707B2 (en)1997-09-182002-07-01PRO1337 polypeptides
US10/187,887Expired - LifetimeUS7285645B2 (en)1997-09-182002-07-01PRO4356 antibodies
US10/187,884AbandonedUS20030036155A1 (en)1997-09-182002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,754AbandonedUS20030036153A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,770Expired - LifetimeUS7358340B2 (en)1997-09-182002-07-02PRO19563 antibodies
US10/187,600AbandonedUS20030036143A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,757Expired - LifetimeUS7276578B2 (en)1997-09-182002-07-02PRO4334 polypeptides
US10/187,743AbandonedUS20030036148A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,602AbandonedUS20030036145A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,769AbandonedUS20030036157A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,745Expired - LifetimeUS7250490B2 (en)1997-09-182002-07-02PRO1480 polypeptides
US10/188,767Expired - LifetimeUS7312310B2 (en)1997-09-182002-07-02PRO6015 polypeptides
US10/188,774AbandonedUS20030040074A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,596AbandonedUS20030032136A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,746AbandonedUS20030036149A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,747GrantedUS20030036150A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,753AbandonedUS20030036152A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,773AbandonedUS20030036159A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,775AbandonedUS20030040075A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,741AbandonedUS20030036147A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,751AbandonedUS20030036151A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,781AbandonedUS20030036160A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,010AbandonedUS20030044932A1 (en)1997-09-182002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,897AbandonedUS20030036164A1 (en)1997-09-182002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,745Expired - LifetimeUS7423120B2 (en)1997-09-182002-07-16PRO19814 polypeptides
US10/199,464AbandonedUS20030032140A1 (en)1997-09-182002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same

Family Applications Before (64)

Application NumberTitlePriority DateFiling Date
US10/173,705AbandonedUS20030032103A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,702AbandonedUS20030170793A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,703AbandonedUS20030170794A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,701AbandonedUS20030104538A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,697AbandonedUS20030032102A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,693AbandonedUS20030073169A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,699AbandonedUS20030166109A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,696AbandonedUS20030082767A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,695AbandonedUS20030032101A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,690AbandonedUS20030166105A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,691AbandonedUS20030166106A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,706AbandonedUS20030022293A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,707AbandonedUS20030166110A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,704AbandonedUS20030170795A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,694AbandonedUS20030166107A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,692AbandonedUS20030166188A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,700AbandonedUS20030027262A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/173,698AbandonedUS20030166108A1 (en)1997-09-182002-06-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,582AbandonedUS20030027265A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,578AbandonedUS20030073170A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,591AbandonedUS20030166115A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,587AbandonedUS20030166113A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,583Expired - Fee RelatedUS7211645B2 (en)1997-09-182002-06-18PRO268 polypeptides
US10/174,574AbandonedUS20030170796A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,585AbandonedUS20030032105A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,581Expired - LifetimeUS7153939B2 (en)1997-09-182002-06-18PRO354 antibodies
US10/174,569AbandonedUS20030166111A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,586AbandonedUS20030032106A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,572AbandonedUS20030027263A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,588AbandonedUS20030027266A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,570AbandonedUS20030211572A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,579AbandonedUS20030027264A1 (en)1997-09-182002-06-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/174,576Expired - Fee RelatedUS7125962B2 (en)1997-09-182002-06-18Anti-Pro268 antibodies
US10/175,753AbandonedUS20030077732A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,745AbandonedUS20030166120A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,750AbandonedUS20030073172A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,748AbandonedUS20030166121A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,739AbandonedUS20030027267A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,751AbandonedUS20030166122A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,747AbandonedUS20030032107A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,743AbandonedUS20030027269A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,752AbandonedUS20030022295A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,741AbandonedUS20030073171A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,735AbandonedUS20030082715A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,738AbandonedUS20030022294A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,742AbandonedUS20030166118A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,754AbandonedUS20030166123A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,736AbandonedUS20030166117A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/175,744AbandonedUS20030166119A1 (en)1997-09-182002-06-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,993AbandonedUS20030027280A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,921AbandonedUS20030027276A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,490AbandonedUS20030170798A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,981AbandonedUS20030170800A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,920AbandonedUS20030166129A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,753AbandonedUS20030044917A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,918Expired - LifetimeUS7495083B2 (en)1997-09-182002-06-20PRO940 antibodies
US10/176,989AbandonedUS20030170803A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,487AbandonedUS20030032110A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,917AbandonedUS20030044918A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,491AbandonedUS20030087373A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,747AbandonedUS20030027273A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,493AbandonedUS20030032111A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,757Expired - Fee RelatedUS7317082B2 (en)1997-09-182002-06-20PRO1018 polypeptides
US10/176,919AbandonedUS20030032114A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same

Family Applications After (154)

Application NumberTitlePriority DateFiling Date
US10/176,484AbandonedUS20030059876A9 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,759AbandonedUS20030166128A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,988AbandonedUS20030170802A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,914AbandonedUS20030017543A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,485AbandonedUS20030032109A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,749AbandonedUS20030017542A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,746AbandonedUS20030068680A1 (en)1997-09-182002-06-20Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,755AbandonedUS20030166127A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,924AbandonedUS20030166131A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,486Expired - LifetimeUS7354999B2 (en)1997-09-182002-06-21PRO1481 polypeptides
US10/176,925AbandonedUS20030032115A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,982AbandonedUS20030044919A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,481AbandonedUS20030032108A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,985AbandonedUS20030027277A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,750AbandonedUS20030027274A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,488AbandonedUS20030027271A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,916AbandonedUS20030040056A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,923AbandonedUS20030068681A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,991AbandonedUS20030027324A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,987AbandonedUS20030027278A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,489AbandonedUS20030166125A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,986AbandonedUS20030073173A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,915AbandonedUS20030017544A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,983AbandonedUS20030170801A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,979AbandonedUS20030087374A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,752AbandonedUS20030170799A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,748AbandonedUS20030040055A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,756AbandonedUS20030032112A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,922AbandonedUS20030166130A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,480AbandonedUS20030166124A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,751AbandonedUS20030036117A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/176,978AbandonedUS20030032116A1 (en)1997-09-182002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,515AbandonedUS20030166135A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,510AbandonedUS20030032117A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,525AbandonedUS20030040060A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,514AbandonedUS20030044922A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,518AbandonedUS20030104540A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,512AbandonedUS20030166134A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,519Expired - Fee RelatedUS7339024B2 (en)1997-09-182002-06-24PRO1772 polypeptides
US10/179,513AbandonedUS20030044921A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,516AbandonedUS20030040058A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,522AbandonedUS20030044923A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,520AbandonedUS20030096353A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,517AbandonedUS20030170805A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,511AbandonedUS20030104539A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,508AbandonedUS20030166133A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,521AbandonedUS20030170806A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,523AbandonedUS20030215909A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,509AbandonedUS20030207392A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,506AbandonedUS20030044920A1 (en)1997-09-182002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,553Expired - LifetimeUS7365156B2 (en)1997-09-182002-06-25PRO1316 polypeptides
US10/180,552Expired - Fee RelatedUS7348415B2 (en)1997-09-182002-06-25PRO1316 antibodies
US10/180,550AbandonedUS20030064440A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,549AbandonedUS20030032122A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,559AbandonedUS20030032124A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,557AbandonedUS20030022301A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,551AbandonedUS20030036123A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,548Expired - Fee RelatedUS7696319B2 (en)1997-09-182002-06-25PRO1772 antibodies
US10/180,546AbandonedUS20030032120A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,543AbandonedUS20030032118A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,545AbandonedUS20030040062A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,547AbandonedUS20030032121A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,541AbandonedUS20030036120A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,560AbandonedUS20030044925A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,556Expired - LifetimeUS7355000B2 (en)1997-09-182002-06-25PRO1380 polypeptides
US10/180,555AbandonedUS20030032123A1 (en)1997-09-182002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,018AbandonedUS20030104541A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,006Expired - LifetimeUS7297776B2 (en)1997-09-182002-06-26PRO1374 antibodies
US10/181,000Expired - LifetimeUS7319137B2 (en)1997-09-182002-06-26PRO1339 polypeptides
US10/183,014AbandonedUS20030064441A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,019Expired - LifetimeUS7425605B2 (en)1997-09-182002-06-26PRO1486 polypeptides
US10/183,005Expired - LifetimeUS7317093B2 (en)1997-09-182002-06-26PRO1339 antibodies
US10/183,017AbandonedUS20030040065A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,009Expired - LifetimeUS7339034B2 (en)1997-09-182002-06-26PRO1305 antibodies
US10/183,012Expired - LifetimeUS7718770B2 (en)1997-09-182002-06-26PRO1305-polypeptides
US10/183,016AbandonedUS20030082717A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,003AbandonedUS20030082716A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,013Expired - LifetimeUS7309769B2 (en)1997-09-182002-06-26PRO1487 polypeptides
US10/183,002AbandonedUS20030054454A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,010AbandonedUS20030032126A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,008AbandonedUS20030040064A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,015AbandonedUS20030044926A1 (en)1997-09-182002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,999Expired - LifetimeUS7297767B2 (en)1997-09-182002-06-26PRO1374 polypeptides
US10/180,998Expired - Fee RelatedUS7087421B2 (en)1997-09-182002-06-26Pro1278 polypeptides
US10/184,630Expired - LifetimeUS7304143B2 (en)1997-09-182002-06-27PRO1571 antibodies
US10/184,654Expired - LifetimeUS7378486B2 (en)1997-09-182002-06-27PRO1482 antibodies
US10/184,633AbandonedUS20030068683A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,615AbandonedUS20030044927A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,638AbandonedUS20030054456A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,619AbandonedUS20030049738A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,627Expired - LifetimeUS7282569B2 (en)1997-09-182002-06-27PRO1508 antibodies
US10/184,652AbandonedUS20030032134A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,642Expired - Fee RelatedUS7332573B2 (en)1997-09-182002-06-27PRO1571 polypeptides
US10/184,627GrantedUS20030040070A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,631AbandonedUS20030036134A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,613AbandonedUS20030119105A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,628Expired - LifetimeUS7309770B2 (en)1997-09-182002-06-27PRO1757 polypeptides
US10/184,612AbandonedUS20030036127A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,618Expired - LifetimeUS7393917B2 (en)1997-09-182002-06-27PRO1482 polypeptides
US10/184,641AbandonedUS20030073174A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,616AbandonedUS20030036128A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,651Expired - LifetimeUS7291704B2 (en)1997-09-182002-06-27PRO1758 polypeptides
US10/184,630GrantedUS20030036133A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,614AbandonedUS20030032128A1 (en)1997-09-182002-06-27Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,632AbandonedUS20030036135A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,624AbandonedUS20030104542A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,646AbandonedUS20030032132A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,647AbandonedUS20030032133A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,637AbandonedUS20030032131A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,655AbandonedUS20030040073A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,620AbandonedUS20030044928A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,643AbandonedUS20030044929A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,644AbandonedUS20030044930A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,617AbandonedUS20030036129A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,623AbandonedUS20030032129A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,626AbandonedUS20030040069A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,629AbandonedUS20030036132A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,635AbandonedUS20030032130A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,636AbandonedUS20030036136A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,650AbandonedUS20030036138A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,625AbandonedUS20030040068A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,656AbandonedUS20030044931A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,657AbandonedUS20030104543A1 (en)1997-09-182002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,622AbandonedUS20030036130A1 (en)1997-09-182002-06-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,598AbandonedUS20030036142A1 (en)1997-09-182002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,601Expired - LifetimeUS7291705B2 (en)1997-09-182002-07-01PRO19645 polypeptides
US10/187,886Expired - LifetimeUS7291708B2 (en)1997-09-182002-07-01PRO1785 polypeptides
US10/187,597AbandonedUS20030036141A1 (en)1997-09-182002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,747Expired - LifetimeUS7291707B2 (en)1997-09-182002-07-01PRO1337 polypeptides
US10/187,887Expired - LifetimeUS7285645B2 (en)1997-09-182002-07-01PRO4356 antibodies
US10/187,884AbandonedUS20030036155A1 (en)1997-09-182002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,754AbandonedUS20030036153A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,770Expired - LifetimeUS7358340B2 (en)1997-09-182002-07-02PRO19563 antibodies
US10/187,600AbandonedUS20030036143A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,757Expired - LifetimeUS7276578B2 (en)1997-09-182002-07-02PRO4334 polypeptides
US10/187,743AbandonedUS20030036148A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,602AbandonedUS20030036145A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,769AbandonedUS20030036157A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,745Expired - LifetimeUS7250490B2 (en)1997-09-182002-07-02PRO1480 polypeptides
US10/188,767Expired - LifetimeUS7312310B2 (en)1997-09-182002-07-02PRO6015 polypeptides
US10/188,774AbandonedUS20030040074A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,596AbandonedUS20030032136A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,746AbandonedUS20030036149A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,747GrantedUS20030036150A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,753AbandonedUS20030036152A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,773AbandonedUS20030036159A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,775AbandonedUS20030040075A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,741AbandonedUS20030036147A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,751AbandonedUS20030036151A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,781AbandonedUS20030036160A1 (en)1997-09-182002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,010AbandonedUS20030044932A1 (en)1997-09-182002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,897AbandonedUS20030036164A1 (en)1997-09-182002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,745Expired - LifetimeUS7423120B2 (en)1997-09-182002-07-16PRO19814 polypeptides
US10/199,464AbandonedUS20030032140A1 (en)1997-09-182002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same

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