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US20030104554A1 - Secreted and transmembrane polypeptides and nucleic acids encoding the same - Google Patents

Secreted and transmembrane polypeptides and nucleic acids encoding the same

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Publication number
US20030104554A1
US20030104554A1US10/205,508US20550802AUS2003104554A1US 20030104554 A1US20030104554 A1US 20030104554A1US 20550802 AUS20550802 AUS 20550802AUS 2003104554 A1US2003104554 A1US 2003104554A1
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United States
Prior art keywords
seq
acid sequence
shows
sequence
amino acid
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US10/205,508
Inventor
Kevin Baker
Jian Chen
Luc Desnoyers
Audrey Goddard
Paul Godowski
Austin Gurney
James Pan
Victoria Smith
Colin Watanabe
William Wood
Zemin Zhang
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Genentech Inc
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Genentech Inc
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Priority claimed from PCT/US2000/008439external-prioritypatent/WO2000073454A1/en
Priority claimed from PCT/US2001/006520external-prioritypatent/WO2001068848A2/en
Priority claimed from US10/052,586external-prioritypatent/US20020127584A1/en
Application filed by Genentech IncfiledCriticalGenentech Inc
Priority to US10/205,508priorityCriticalpatent/US20030104554A1/en
Publication of US20030104554A1publicationCriticalpatent/US20030104554A1/en
Abandonedlegal-statusCriticalCurrent

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Abstract

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Description

Claims (24)

What is claimed is:
1. Isolated nucleic acid having at least 80% nucleic acid sequence identity to a nucleotide sequence that encodes an amino acid sequence selected from the group consisting of the amino acid sequence shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), and FIG. 610 (SEQ ID NO: 610).
2. Isolated nucleic acid having at least 80% nucleic acid sequence identity to a nucleotide sequence selected from the group consisting of the nucleotide sequence shown in FIG. 1 (SEQ ID NO: 1), FIG. 3 (SEQ ID NO: 3), FIG. 5 (SEQ ID NO: 5), FIG. 7 (SEQ ID NO: 7), FIG. 9 (SEQ ID NO: 9), FIG. 11 (SEQ ID NO: 11), FIG. 13 (SEQ ID NO: 13), FIG. 15 (SEQ ID NO: 15), FIG. 17 (SEQ ID NO: 17), FIG. 19 (SEQ ID NO: 19), FIG. 21 (SEQ ID NO: 21), FIG. 23 (SEQ ID NO: 23), FIG. 25 (SEQ ID NO: 25), FIG. 27 (SEQ ID NO: 27), FIG. 29 (SEQ ID NO: 29), FIG. 31 (SEQ ID NO: 31), FIG. 33 (SEQ ID NO: 33), FIG. 35 (SEQ ID NO: 35), FIG. 37 (SEQ ID NO: 37), FIG. 39 (SEQ ID NO: 39), FIG. 41 (SEQ ID NO: 41), FIG. 43 (SEQ ID NO: 43), FIG. 45 (SEQ ID NO: 45), FIG. 47 (SEQ ID NO: 47), FIG. 49 (SEQ ID NO: 49), FIG. 51 (SEQ ID NO: 51), FIG. 53 (SEQ ID NO: 53), FIG. 55 (SEQ ID NO: 55), FIG. 57 (SEQ ID NO: 57), FIG. 59 (SEQ ID NO: 59), FIG. 61 (SEQ ID NO: 61), FIG. 63 (SEQ ID NO: 63), FIG. 65 (SEQ ID NO: 65), FIG. 67 (SEQ ID NO: 67), FIG. 69 (SEQ ID NO: 69), FIG. 71 (SEQ ID NO: 71), FIG. 73 (SEQ ID NO: 73), FIGS.75A-75B (SEQ ID NO: 75), FIG. 77 (SEQ ID NO: 77), FIG. 79 (SEQ ID NO: 79), FIG. 81 (SEQ ID NO: 81), FIG. 83 (SEQ ID NO: 83), FIG. 85 (SEQ ID NO: 85), FIG. 87 (SEQ ID NO: 87), FIG. 89 (SEQ ID NO: 89), FIG. 91 (SEQ ID NO: 91), FIG. 93 (SEQ ID NO: 93), FIG. 95 (SEQ ID NO: 95), FIG. 97 (SEQ ID NO: 97), FIG. 99 (SEQ ID NO: 99), FIG. 101 (SEQ ID NO: 101), FIG. 103 (SEQ ID NO: 103), FIG. 105 (SEQ ID NO: 105), FIG. 107 (SEQ ID NO: 107), FIG. 109 (SEQ ID NO: 109), FIG. 111 (SEQ ID NO: 111), FIG. 113 (SEQ ID NO: 113), FIG. 115 (SEQ ID NO: 115), FIG. 117 (SEQ ID NO: 117), FIG. 119 (SEQ ID NO: 119), FIG. 121 (SEQ ID NO: 121), FIG. 123 (SEQ ID NO: 123), FIG. 125 (SEQ ID NO: 125), FIG. 127 (SEQ ID NO: 127), FIG. 129 (SEQ ID NO: 129), FIG. 131 (SEQ ID NO: 131), FIG. 133 (SEQ ID NO: 133), FIG. 135 (SEQ ID NO: 135), FIG. 137 (SEQ ID NO: 137), FIG. 139 (SEQ ID NO: 139), FIG. 141 (SEQ ID NO: 141), FIG. 143 (SEQ ID NO: 143), FIG. 145 (SEQ ID NO: 145), FIG. 147 (SEQ ID NO: 147), FIG. 149 (SEQ ID NO: 149), FIG. 151 (SEQ ID NO: 151), FIG. 153 (SEQ ID NO: 153), FIG. 155 (SEQ ID NO: 155), FIG. 157 (SEQ ID NO: 157), FIG. 159 (SEQ ID NO: 159), FIG. 161 (SEQ ID NO: 161), FIG. 163 (SEQ ID NO: 163), FIG. 165 (SEQ ID NO: 165), FIG. 167 (SEQ ID NO: 167), FIG. 169 (SEQ ID NO: 169), FIG. 171 (SEQ ID NO: 171), FIG. 173 (SEQ ID NO: 173), FIG. 175 (SEQ ID NO: 175), FIG. 177 (SEQ ID NO: 177), FIG. 179 (SEQ ID NO: 179), FIG. 181 (SEQ ID NO: 181), FIG. 183 (SEQ ID NO: 183), FIG. 185 (SEQ ID NO: 185), FIG. 187 (SEQ ID NO: 187), FIG. 189 (SEQ ID NO: 189), FIG. 191 (SEQ ID NO: 191), FIG. 193 (SEQ ID NO: 193), FIG. 195 (SEQ ID NO: 195), FIG. 197 (SEQ ID NO: 197), FIG. 199 (SEQ ID NO: 199), FIG. 201 (SEQ ID NO: 201), FIG. 203 (SEQ ID NO: 203), FIG. 205 (SEQ ID NO: 205), FIG. 207 (SEQ ID NO: 207), FIG. 209 (SEQ ID NO: 209), FIG. 211 (SEQ ID NO: 211), FIG. 213 (SEQ ID NO: 213), FIG. 215 (SEQ ID NO: 215), FIG. 217 (SEQ ID NO: 217), FIG. 219 (SEQ ID NO: 219), FIG. 221 (SEQ ID NO: 221), FIG. 223 (SEQ ID NO: 223), FIG. 225 (SEQ ID NO: 225), FIG. 227 (SEQ ID NO: 227), FIG. 229 (SEQ ID NO: 229), FIG. 231 (SEQ ID NO: 231), FIG. 233 (SEQ ID NO: 233), FIG. 235 (SEQ ID NO: 235), FIG. 237 (SEQ ID NO: 237), FIG. 239 (SEQ ID NO: 239), FIG. 241 (SEQ ID NO: 241), FIG. 243 (SEQ ID NO: 243), FIG. 245 (SEQ ID NO: 245), FIG. 247 (SEQ ID NO: 247), FIG. 249 (SEQ ID NO: 249), FIG. 251 (SEQ ID NO: 251), FIG. 253 (SEQ ID NO: 253), FIG. 255 (SEQ ID NO: 255), FIG. 257 (SEQ ID NO: 257), FIG. 259 (SEQ ID NO: 259), FIG. 261 (SEQ ID NO: 261), FIG. 263 (SEQ ID NO: 263), FIG. 265 (SEQ ID NO: 265), FIG. 267 (SEQ ID NO: 267), FIG. 269 (SEQ ID NO: 269), FIG. 271 (SEQ ID NO: 271), FIG. 273 (SEQ ID NO: 273), FIG. 275 (SEQ ID NO: 275), FIG. 277 (SEQ ID NO: 277), FIG. 279 (SEQ ID NO: 279), FIG. 281 (SEQ ID NO: 281), FIG. 283 (SEQ ID NO: 283), FIG. 285 (SEQ ID NO: 285), FIG. 287 (SEQ ID NO: 287), FIGS.289A-289B (SEQ ID NO: 289), FIG. 291 (SEQ ID NO: 291), FIG. 293 (SEQ ID NO: 293), FIG. 295 (SEQ ID NO: 295), FIG. 297 (SEQ ID NO: 297), FIG. 299 (SEQ ID NO: 299), FIG. 301 (SEQ ID NO: 301), FIG. 303 (SEQ ID NO: 303), FIG. 305 (SEQ ID NO: 305), FIG. 307 (SEQ ID NO: 307), FIG. 309 (SEQ ID NO: 309), FIGS.311A-311B (SEQ ID NO: 311), FIG. 313 (SEQ ID NO: 313), FIG. 315 (SEQ ID NO: 315), FIG. 317 (SEQ ID NO: 317), FIG. 319 (SEQ ID NO: 319), FIG. 321 (SEQ ID NO: 321), FIG. 323 (SEQ ID NO: 323), FIG. 325 (SEQ ID NO: 325), FIG. 327 (SEQ ID NO: 327), FIG. 329 (SEQ ID NO: 329), FIG. 331 (SEQ ID NO: 331), FIG. 333 (SEQ ID NO: 333), FIG. 335 (SEQ ID NO: 335), FIG. 337 (SEQ ID NO: 337), FIG. 339 (SEQ ID NO: 339), FIG. 341 (SEQ ID NO: 341), FIG. 343 (SEQ ID NO: 343), FIG. 345 (SEQ ID NO: 345), FIG. 347 (SEQ ID NO: 347), FIG. 349 (SEQ ID NO: 349), FIGS.351A-351B (SEQ ID NO: 351), FIG. 353 (SEQ ID NO: 353), FIG. 355 (SEQ ID NO: 355), FIG. 357 (SEQ ID NO: 357), FIG. 359 (SEQ ID NO: 359), FIG. 361 (SEQ ID NO: 361), FIG. 363 (SEQ ID NO: 363), FIG. 365 (SEQ ID NO: 365), FIG. 367 (SEQ ID NO: 367), FIG. 369 (SEQ ID NO: 369), FIG. 371 (SEQ ID NO: 371), FIG. 373 (SEQ ID NO: 373), FIG. 375 (SEQ ID NO: 375), FIG. 377 (SEQ ID NO: 377), FIG. 379 (SEQ ID NO: 379), FIG. 381 (SEQ ID NO: 381), FIG. 383 (SEQ ID NO: 383), FIG. 385 (SEQ ID NO: 385), FIG. 387 (SEQ ID NO: 387), FIG. 389 (SEQ ID NO: 389), FIG. 391 (SEQ ID NO: 391), FIG. 393 (SEQ ID NO: 393), FIG. 395 (SEQ ID NO: 395), FIG. 397 (SEQ ID NO: 397), FIG. 399 (SEQ ID NO: 399), FIG. 401 (SEQ ID NO: 401), FIG. 403 (SEQ ID NO: 403), FIG. 405 (SEQ ID NO: 405), FIG. 407 (SEQ ID NO: 407), FIG. 409 (SEQ ID NO: 409), FIG. 411 (SEQ ID NO: 41 1), FIG. 413 (SEQ ID NO: 413), FIG. 415 (SEQ ID NO: 415), FIG. 417 (SEQ ID NO: 417), FIG. 419 (SEQ ID NO: 419), FIG. 421 (SEQ ID NO: 421), FIG. 423 (SEQ ID NO: 423), FIG. 425 (SEQ ID NO: 425), FIG. 427 (SEQ ID NO: 427), FIG.429 (SEQ ID NO: 429), FIG. 431 (SEQ ID NO: 431), FIG. 433 (SEQ ID NO: 433), FIG. 435 (SEQ ID NO: 435), FIG. 437 (SEQ ID NO: 437), FIG. 439 (SEQ ID NO: 439), FIG. 441 (SEQ ID NO: 441), FIG. 443 (SEQ ID NO: 443), FIG. 445 (SEQ ID NO: 445), FIG. 447 (SEQ ID NO: 447), FIG. 449 (SEQ ID NO: 449), FIG. 451 (SEQ ID NO: 451), FIG. 453 (SEQ ID NO: 453), FIG. 455 (SEQ ID NO: 455), FIG. 457 (SEQ ID NO: 457), FIG. 459 (SEQ ID NO: 459), FIG. 461 (SEQ ID NO: 461), FIG. 463 (SEQ ID NO: 463), FIG. 465 (SEQ ID NO: 465), FIG. 467 (SEQ ID NO: 467), FIG. 469 (SEQ ID NO: 469), FIG. 471 (SEQ ID NO: 471), FIG. 473 (SEQ ID NO: 473), FIG. 475 (SEQ ID NO: 475), FIG. 477 (SEQ ID NO: 477), FIG. 479 (SEQ ID NO: 479), FIG. 481 (SEQ ID NO: 481), FIG. 483 (SEQ ID NO: 483), FIG. 485 (SEQ ID NO: 485), FIG. 487 (SEQ ID NO: 487), FIG. 489 (SEQ ID NO: 489), FIG. 491 (SEQ ID NO: 491), FIG. 493 (SEQ ID NO: 493), FIG. 495 (SEQ ID NO: 495), FIG. 497 (SEQ ID NO: 497), FIG. 499 (SEQ ID NO: 499), FIG. 501 (SEQ ID NO: 501), FIG. 503 (SEQ ID NO: 503), FIG. 505 (SEQ ID NO: 505), FIG. 507 (SEQ ID NO: 507), FIG. 509 (SEQ ID NO: 509), FIG. 511 (SEQ ID NO: 511), FIG. 513 (SEQ ID NO: 513), FIG. 515 (SEQ ID NO: 515), FIG. 517 (SEQ ID NO: 517), FIG. 519 (SEQ ID NO: 519), FIG. 521 (SEQ ID NO: 521), FIG. 523 (SEQ ID NO: 523), FIGS.525A-525B (SEQ ID NO: 525), FIG. 527 (SEQ ID NO: 527), FIG. 529 (SEQ ID NO: 529), FIG. 531 (SEQ ID NO: 531), FIG. 533 (SEQ ID NO: 533), FIG. 535 (SEQ ID NO: 535), FIG. 537 (SEQ ID NO: 537), FIG. 539 (SEQ ID NO: 539), FIG. 541 (SEQ ID NO: 541), FIG. 543 (SEQ ID NO: 543), FIG. 545 (SEQ ID NO: 545), FIG. 547 (SEQ ID NO: 547), FIG. 549 (SEQ ID NO: 549), FIG. 551 (SEQ ID NO: 551), FIG. 553 (SEQ ID NO: 553), FIG. 555 (SEQ ID NO: 555), FIG. 557 (SEQ ID NO: 557), FIG. 559 (SEQ ID NO: 559), FIG. 561 (SEQ ID NO: 561), FIG. 563 (SEQ ID NO: 563), FIG. 565 (SEQ ID NO: 565), FIG. 567 (SEQ ID NO: 567), FIG. 569 (SEQ ID NO: 569), FIG. 571 (SEQ ID NO: 571), FIG. 573 (SEQ ID NO: 573), FIG. 575 (SEQ ID NO: 575), FIG. 577 (SEQ ID NO: 577), FIG. 579 (SEQ ID NO: 579), FIG. 581 (SEQ ID NO: 581), FIG. 583 (SEQ ID NO: 583), FIG. 585 (SEQ ID NO: 585), FIG. 587 (SEQ ID NO: 587), FIG. 589 (SEQ ID NO: 589), FIG. 591 (SEQ ID NO: 591), FIG. 593 (SEQ ID NO: 593), FIG. 595 (SEQ ID NO: 595), FIG. 597 (SEQ ID NO: 597), FIG. 599 (SEQ ID NO: 599), FIG. 601 (SEQ ID NO: 601), FIG. 603 (SEQ ID NO: 603), FIG. 605 (SEQ ID NO: 605), FIG. 607 (SEQ ID NO: 607), and FIG. 609 (SEQ ID NO: 609).
3. Isolated nucleic acid having at least 80% nucleic acid sequence identity to a nucleotide sequence selected from the group consisting of the full-length coding sequence of the nucleotide sequence shown in FIG. 1 (SEQ ID NO: 1), FIG. 3 (SEQ ID NO: 3), FIG. 5 (SEQ ID NO: 5), FIG. 7 (SEQ ID NO: 7), FIG. 9 (SEQ ID NO: 9), FIG. 11 (SEQ ID NO: 11), FIG. 13 (SEQ ID NO: 13), FIG. 15 (SEQ ID NO: 15), FIG. 17 (SEQ ID NO: 17), FIG. 19 (SEQ ID NO: 19), FIG. 21 (SEQ ID NO: 21), FIG. 23 (SEQ ID NO: 23), FIG. 25 (SEQ ID NO: 25), FIG. 27 (SEQ ID NO: 27), FIG. 29 (SEQ ID NO: 29), FIG. 31 (SEQ ID NO: 31), FIG. 33 (SEQ ID NO: 33), FIG. 35 (SEQ ID NO: 35), FIG. 37 (SEQ ID NO: 37), FIG. 39 (SEQ ID NO: 39), FIG. 41 (SEQ ID NO: 41), FIG. 43 (SEQ ID NO: 43), FIG. 45 (SEQ ID NO: 45), FIG. 47 (SEQ ID NO: 47), FIG. 49 (SEQ ID NO: 49), FIG. 51 (SEQ ID NO: 51), FIG. 53 (SEQ ID NO: 53), FIG. 55 (SEQ ID NO: 55), FIG. 57 (SEQ ID NO: 57), FIG. 59 (SEQ ID NO: 59), FIG. 61 (SEQ ID NO: 61), FIG. 63 (SEQ ID NO: 63), FIG. 65 (SEQ ID NO: 65), FIG. 67 (SEQ ID NO: 67), FIG. 69 (SEQ ID NO: 69), FIG. 71 (SEQ ID NO: 71), FIG. 73 (SEQ ID NO: 73), FIGS.75A-75B (SEQ ID NO: 75), FIG. 77 (SEQ ID NO: 77), FIG. 79 (SEQ ID NO: 79), FIG. 81 (SEQ ID NO: 81), FIG. 83 (SEQ ID NO: 83), FIG. 85 (SEQ ID NO: 85), FIG. 87 (SEQ ID NO: 87), FIG. 89 (SEQ ID NO: 89), FIG. 91 (SEQ ID NO: 91), FIG. 93 (SEQ ID NO: 93), FIG. 95 (SEQ ID NO: 95), FIG. 97 (SEQ ID NO: 97), FIG. 99 (SEQ ID NO: 99), FIG. 101 (SEQ ID NO: 101), FIG. 103 (SEQ ID NO: 103), FIG. 105 (SEQ ID NO: 105), FIG. 107 (SEQ ID NO: 107), FIG. 109 (SEQ ID NO: 109), FIG. 111 (SEQ ID NO: 111), FIG. 113 (SEQ ID NO: 113), FIG. 115 (SEQ ID NO: 115), FIG. 117 (SEQ ID NO: 117), FIG. 119 (SEQ ID NO: 119), FIG. 121 (SEQ ID NO: 121), FIG. 123 (SEQ ID NO: 123), FIG. 125 (SEQ ID NO: 125), FIG. 127 (SEQ ID NO: 127), FIG. 129 (SEQ ID NO: 129), FIG. 131 (SEQ ID NO: 131), FIG. 133 (SEQ ID NO: 133), FIG. 135 (SEQ ID NO: 135), FIG. 137 (SEQ ID NO: 137), FIG. 139 (SEQ ID NO: 139), FIG. 141 (SEQ ID NO: 141), FIG. 143 (SEQ ID NO: 143), FIG. 145 (SEQ ID NO: 145), FIG. 147 (SEQ ID NO: 147), FIG. 149 (SEQ ID NO: 149), FIG. 151 (SEQ ID NO: 151), FIG. 153 (SEQ ID NO: 153), FIG. 155 (SEQ ID NO: 155), FIG. 157 (SEQ ID NO: 157), FIG. 159 (SEQ ID NO: 159), FIG. 161 (SEQ ID NO: 161), FIG. 163 (SEQ ID NO: 163), FIG. 165 (SEQ ID NO: 165), FIG. 167 (SEQ ID NO: 167), FIG. 169 (SEQ ID NO: 169), FIG. 171 (SEQ ID NO: 171), FIG. 173 (SEQ ID NO: 173), FIG. 175 (SEQ ID NO: 175), FIG. 177 (SEQ ID NO: 177), FIG. 179 (SEQ ID NO: 179), FIG. 181 (SEQ ID NO: 181), FIG. 183 (SEQ ID NO: 183), FIG. 185 (SEQ ID NO: 185), FIG. 187 (SEQ ID NO: 187), FIG. 189 (SEQ ID NO: 189), FIG. 191 (SEQ ID NO: 191), FIG. 193 (SEQ ID NO: 193), FIG. 195 (SEQ ID NO: 195), FIG. 197 (SEQ ID NO: 197), FIG. 199 (SEQ ID NO: 199), FIG. 201 (SEQ ID NO: 201), FIG. 203 (SEQ ID NO: 203), FIG. 205 (SEQ ID NO: 205), FIG. 207 (SEQ ID NO: 207), FIG. 209 (SEQ ID NO: 209), FIG. 211 (SEQ ID NO: 211), FIG. 213 (SEQ ID NO: 213), FIG. 215 (SEQ ID NO: 215), FIG. 217 (SEQ ID NO: 217), FIG. 219 (SEQ ID NO: 219), FIG. 221 (SEQ ID NO: 221), FIG. 223 (SEQ ID NO: 223), FIG. 225 (SEQ ID NO: 225), FIG. 227 (SEQ ID NO: 227), FIG. 229 (SEQ ID NO: 229), FIG. 231 (SEQ ID NO: 231), FIG. 233 (SEQ ID NO: 233), FIG. 235 (SEQ ID NO: 235), FIG. 237 (SEQ ID NO: 237), FIG. 239 (SEQ ID NO: 239), FIG. 241 (SEQ ID NO: 241), FIG. 243 (SEQ ID NO: 243), FIG. 245 (SEQ ID NO: 245), FIG. 247 (SEQ ID NO: 247), FIG. 249 (SEQ ID NO: 249), FIG. 251 (SEQ ID NO: 251), FIG. 253 (SEQ ID NO: 253), FIG. 255 (SEQ ID NO: 255), FIG. 257 (SEQ ID NO: 257), FIG. 259 (SEQ ID NO: 259), FIG. 261 (SEQ ID NO: 261), FIG. 263 (SEQ ID NO: 263), FIG. 265 (SEQ ID NO: 265), FIG. 267 (SEQ ID NO: 267), FIG. 269 (SEQ ID NO: 269), FIG. 271 (SEQ ID NO: 271), FIG. 273 (SEQ ID NO: 273), FIG. 275 (SEQ ID NO: 275), FIG. 277 (SEQ ID NO: 277), FIG. 279 (SEQ ID NO: 279), FIG. 281 (SEQ ID NO: 281), FIG. 283 (SEQ ID NO: 283), FIG. 285 (SEQ ID NO: 285), FIG. 287 (SEQ ID NO: 287), FIGS.289A-289B (SEQ ID NO: 289), FIG. 291 (SEQ ID NO: 291), FIG. 293 (SEQ ID NO: 293), FIG. 295 (SEQ ID NO: 295), FIG. 297 (SEQ ID NO: 297), FIG. 299 (SEQ ID NO: 299), FIG. 301 (SEQ ID NO: 301), FIG. 303 (SEQ ID NO: 303), FIG. 305 (SEQ ID NO: 305), FIG. 307 (SEQ ID NO: 307), FIG. 309 (SEQ ID NO: 309), FIGS.311A-311B (SEQ ID NO: 311), FIG. 313 (SEQ ID NO: 313), FIG. 315 (SEQ ID NO: 315), FIG. 317 (SEQ ID NO: 317), FIG. 319 (SEQ ID NO: 319), FIG. 321 (SEQ ID NO: 321), FIG. 323 (SEQ ID NO: 323), FIG. 325 (SEQ ID NO: 325), FIG. 327 (SEQ ID NO: 327), FIG. 329 (SEQ ID NO: 329), FIG. 331 (SEQ ID NO: 331), FIG. 333 (SEQ ID NO: 333), FIG. 335 (SEQ ID NO: 335), FIG. 337 (SEQ ID NO: 337), FIG. 339 (SEQ ID NO: 339), FIG. 341 (SEQ ID NO: 341), FIG. 343 (SEQ ID NO: 343), FIG. 345 (SEQ ID NO: 345), FIG. 347 (SEQ ID NO: 347), FIG. 349 (SEQ ID NO: 349), FIGS.351A-351B (SEQ ID NO: 351), FIG. 353 (SEQ ID NO: 353), FIG. 355 (SEQ ID NO: 355), FIG. 357 (SEQ ID NO: 357), FIG. 359 (SEQ ID NO: 359), FIG. 361 (SEQ ID NO: 361), FIG. 363 (SEQ ID NO: 363), FIG. 365 (SEQ ID NO: 365), FIG. 367 (SEQ ID NO: 367), FIG. 369 (SEQ ID NO: 369), FIG. 371 (SEQ ID NO: 371), FIG. 373 (SEQ ID NO: 373), FIG. 375 (SEQ ID NO: 375), FIG. 377 (SEQ ID NO: 377), FIG. 379 (SEQ ID NO: 379), FIG. 381 (SEQ ID NO: 381), FIG. 383 (SEQ ID NO: 383), FIG. 385 (SEQ ID NO: 385), FIG. 387 (SEQ ID NO: 387), FIG. 389 (SEQ ID NO: 389), FIG. 391 (SEQ ID NO: 391), FIG. 393 (SEQ ID NO: 393), FIG. 395 (SEQ ID NO: 395), FIG. 397 (SEQ ID NO: 397), FIG. 399 (SEQ ID NO: 399), FIG. 401 (SEQ ID NO: 401), FIG. 403 (SEQ ID NO: 403), FIG. 405 (SEQ ID NO: 405), FIG. 407 (SEQ ID NO: 407), FIG. 409 (SEQ ID NO: 409), FIG. 411 (SEQ ID NO: 411), FIG. 413 (SEQ ID NO: 413), FIG. 415 (SEQ ID NO: 415), FIG. 417 (SEQ ID NO: 417), FIG. 419 (SEQ ID NO: 419), FIG. 421 (SEQ ID NO: 421), FIG. 423 (SEQ ID NO: 423), FIG. 425 (SEQ ID NO: 425), FIG. 427 (SEQ ID NO: 427), FIG. 429 (SEQ ID NO: 429), FIG. 431 (SEQ ID NO: 431), FIG. 433 (SEQ ID NO: 433), FIG. 435 (SEQ ID NO: 435), FIG. 437 (SEQ ID NO: 437), FIG. 439 (SEQ ID NO: 439), FIG. 441 (SEQ ID NO: 441), FIG. 443 (SEQ ID NO: 443), FIG. 445 (SEQ ID NO: 445), FIG. 447 (SEQ ID NO: 447), FIG. 449 (SEQ ID NO: 449), FIG. 451 (SEQ ID NO: 451), FIG. 453 (SEQ ID NO: 453), FIG. 455 (SEQ ID NO: 455), FIG. 457 (SEQ ID NO: 457), FIG. 459 (SEQ ID NO: 459), FIG. 461 (SEQ ID NO: 461), FIG. 463 (SEQ ID NO: 463), FIG. 465 (SEQ ID NO: 465), FIG. 467 (SEQ ID NO: 467), FIG. 469 (SEQ ID NO: 469), FIG. 471 (SEQ ID NO: 471), FIG. 473 (SEQ ID NO: 473), FIG. 475 (SEQ ID NO: 475), FIG. 477 (SEQ ID NO: 477), FIG. 479 (SEQ ID NO: 479), FIG. 481 (SEQ ID NO: 481), FIG. 483 (SEQ ID NO: 483), FIG. 485 (SEQ ID NO: 485), FIG. 487 (SEQ ID NO: 487), FIG. 489 (SEQ ID NO: 489), FIG. 491 (SEQ ID NO: 491), FIG. 493 (SEQ ID NO: 493), FIG. 495 (SEQ ID NO: 495), FIG. 497 (SEQ ID NO: 497), FIG. 499 (SEQ ID NO: 499), FIG. 501 (SEQ ID NO: 501), FIG. 503 (SEQ ID NO: 503), FIG. 505 (SEQ ID NO: 505), FIG. 507 (SEQ ID NO: 507), FIG. 509 (SEQ ID NO: 509), FIG. 511 (SEQ ID NO: 511), FIG. 513 (SEQ ID NO: 513), FIG. 515 (SEQ ID NO: 515), FIG. 517 (SEQ ID NO: 517), FIG. 519 (SEQ ID NO: 519), FIG. 521 (SEQ ID NO: 521), FIG. 523 (SEQ ID NO: 523), FIGS.525A-525B (SEQ ID NO: 525), FIG. 527 (SEQ ID NO: 527), FIG. 529 (SEQ ID NO: 529), FIG. 531 (SEQ ID NO: 531), FIG. 533 (SEQ ID NO: 533), FIG. 535 (SEQ ID NO: 535), FIG. 537 (SEQ ID NO: 537), FIG. 539 (SEQ ID NO: 539), FIG. 541 (SEQ ID NO: 541), FIG. 543 (SEQ ID NO: 543), FIG. 545 (SEQ ID NO: 545), FIG. 547 (SEQ ID NO: 547), FIG. 549 (SEQ ID NO: 549), FIG. 551 (SEQ ID NO: 551), FIG. 553 (SEQ ID NO: 553), FIG. 555 (SEQ ID NO: 555), FIG. 557 (SEQ ID NO: 557), FIG. 559 (SEQ ID NO: 559), FIG. 561 (SEQ ID NO: 561), FIG. 563 (SEQ ID NO: 563), FIG. 565 (SEQ ID NO: 565), FIG. 567 (SEQ ID NO: 567), FIG. 569 (SEQ ID NO: 569), FIG. 571 (SEQ ID NO: 571), FIG. 573 (SEQ ID NO: 573), FIG. 575 (SEQ ID NO: 575), FIG. 577 (SEQ ID NO: 577), FIG. 579 (SEQ ID NO: 579), FIG. 581 (SEQ ID NO: 581), FIG. 583 (SEQ ID NO: 583), FIG. 585 (SEQ ID NO: 585), FIG. 587 (SEQ ID NO: 587), FIG. 589 (SEQ ID NO: 589), FIG. 591 (SEQ ID NO: 591), FIG. 593 (SEQ ID NO: 593), FIG. 595 (SEQ ID NO: 595), FIG. 597 (SEQ ID NO: 597), FIG. 599 (SEQ ID NO: 599), FIG. 601 (SEQ ID NO: 601), FIG. 603 (SEQ ID NO: 603), FIG. 605 (SEQ ID NO: 605), FIG. 607 (SEQ ID NO: 607), and FIG. 609 (SEQ ID NO: 609).
4. Isolated nucleic acid having at least 80% nucleic acid sequence identity to the full-length coding sequence of the DNA deposited under any ATCC accession number shown in Table 7.
5. A vector comprising the nucleic acid ofclaim 1.
6. A host cell comprising the vector ofclaim 5.
7. The host cell ofclaim 6, wherein said cell is a CHO cell.
8. The host cell ofclaim 6, wherein said cell is anE. coli.
9. The host cell ofclaim 6, wherein said cell is a yeast cell.
10. A process for producing a PRO polypeptide comprising culturing the host cell ofclaim 6 under conditions suitable for expression of said PRO polypeptide and recovering said PRO polypeptide from the cell culture.
11. An isolated polypeptide having at least 80% amino acid sequence identity to an amino acid sequence selected from the group consisting of the amino acid sequence shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), and FIG. 610 (SEQ ID NO: 610).
12. An isolated polypeptide having at least 80% amino acid sequence identity to an amino acid sequence encoded by the full-length coding sequence of the DNA deposited under any ATCC accession number shown in Table 7.
13. A chimeric molecule comprising a polypeptide according toclaim 11 fused to a heterologous amino acid sequence.
14. The chimeric molecule ofclaim 13, wherein said heterologous amino acid sequence is an epitope tag sequence.
15. The chimeric molecule ofclaim 13, wherein said heterologous amino acid sequence is a Fc region of an immunoglobulin.
16. An antibody which specifically binds to a polypeptide according toclaim 11.
17. The antibody ofclaim 16, wherein said antibody is a monoclonal antibody, a humanized antibody or a single-chain antibody.
18. Isolated nucleic acid having at least 80% nucleic acid sequence identity to:
(a) a nucleotide sequence encoding the polypeptide shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), lacking its associated signal peptide;
(b) a nucleotide sequence encoding an extracellular domain of the polypeptide shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG.94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 360 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), with its associated signal peptide; or
(c) a nucleotide sequence encoding an extracellular domain of the polypeptide shown in FIG.2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), lacking its associated signal peptide.
19. An isolated polypeptide having at least 80% amino acid sequence identity to:
(a) an amino acid sequence of the polypeptide shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), lacking its associated signal peptide;
(b) an amino acid sequence of an extracellular domain of the polypeptide shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 88), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 110), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), with its associated signal peptide; or
(c) an amino acid sequence of an extracellular domain of the polypeptide shown in FIG. 2 (SEQ ID NO: 2), FIG. 4 (SEQ ID NO: 4), FIG. 6 (SEQ ID NO: 6), FIG. 8 (SEQ ID NO: 8), FIG. 10 (SEQ ID NO: 10), FIG. 12 (SEQ ID NO: 12), FIG. 14 (SEQ ID NO: 14), FIG. 16 (SEQ ID NO: 16), FIG. 18 (SEQ ID NO: 18), FIG. 20 (SEQ ID NO: 20), FIG. 22 (SEQ ID NO: 22), FIG. 24 (SEQ ID NO: 24), FIG. 26 (SEQ ID NO: 26), FIG. 28 (SEQ ID NO: 28), FIG. 30 (SEQ ID NO: 30), FIG. 32 (SEQ ID NO: 32), FIG. 34 (SEQ ID NO: 34), FIG. 36 (SEQ ID NO: 36), FIG. 38 (SEQ ID NO: 38), FIG. 40 (SEQ ID NO: 40), FIG. 42 (SEQ ID NO: 42), FIG. 44 (SEQ ID NO: 44), FIG. 46 (SEQ ID NO: 46), FIG. 48 (SEQ ID NO: 48), FIG. 50 (SEQ ID NO: 50), FIG. 52 (SEQ ID NO: 52), FIG. 54 (SEQ ID NO: 54), FIG. 56 (SEQ ID NO: 56), FIG. 58 (SEQ ID NO: 58), FIG. 60 (SEQ ID NO: 60), FIG. 62 (SEQ ID NO: 62), FIG. 64 (SEQ ID NO: 64), FIG. 66 (SEQ ID NO: 66), FIG. 68 (SEQ ID NO: 68), FIG. 70 (SEQ ID NO: 70), FIG. 72 (SEQ ID NO: 72), FIG. 74 (SEQ ID NO: 74), FIG. 76 (SEQ ID NO: 76 ), FIG. 78 (SEQ ID NO: 78), FIG. 80 (SEQ ID NO: 80), FIG. 82 (SEQ ID NO: 82), FIG. 84 (SEQ ID NO: 84), FIG. 86 (SEQ ID NO: 86), FIG. 88 (SEQ ID NO: 8 8), FIG. 90 (SEQ ID NO: 90), FIG. 92 (SEQ ID NO: 92), FIG. 94 (SEQ ID NO: 94), FIG. 96 (SEQ ID NO: 96), FIG. 98 (SEQ ID NO: 98), FIG. 100 (SEQ ID NO: 100), FIG. 102 (SEQ ID NO: 102), FIG. 104 (SEQ ID NO: 104), FIG. 106 (SEQ ID NO: 106), FIG. 108 (SEQ ID NO: 108), FIG. 110 (SEQ ID NO: 10), FIG. 112 (SEQ ID NO: 112), FIG. 114 (SEQ ID NO: 114), FIG. 116 (SEQ ID NO: 116), FIG. 118 (SEQ ID NO: 118), FIG. 120 (SEQ ID NO: 120), FIG. 122 (SEQ ID NO: 122), FIG. 124 (SEQ ID NO: 124), FIG. 126 (SEQ ID NO: 126), FIG. 128 (SEQ ID NO: 128), FIG. 130 (SEQ ID NO: 130), FIG. 132 (SEQ ID NO: 132), FIG. 134 (SEQ ID NO: 134), FIG. 136 (SEQ ID NO: 136), FIG. 138 (SEQ ID NO: 138), FIG. 140 (SEQ ID NO: 140), FIG. 142 (SEQ ID NO: 142), FIG. 144 (SEQ ID NO: 144), FIG. 146 (SEQ ID NO: 146), FIG. 148 (SEQ ID NO: 148), FIG. 150 (SEQ ID NO: 150), FIG. 152 (SEQ ID NO: 152), FIG. 154 (SEQ ID NO: 154), FIG. 156 (SEQ ID NO: 156), FIG. 158 (SEQ ID NO: 158), FIG. 160 (SEQ ID NO: 160), FIG. 162 (SEQ ID NO: 162), FIG. 164 (SEQ ID NO: 164), FIG. 166 (SEQ ID NO: 166), FIG. 168 (SEQ ID NO: 168), FIG. 170 (SEQ ID NO: 170), FIG. 172 (SEQ ID NO: 172), FIG. 174 (SEQ ID NO: 174), FIG. 176 (SEQ ID NO: 176), FIG. 178 (SEQ ID NO: 178), FIG. 180 (SEQ ID NO: 180), FIG. 182 (SEQ ID NO: 182), FIG. 184 (SEQ ID NO: 184), FIG. 186 (SEQ ID NO: 186), FIG. 188 (SEQ ID NO: 188), FIG. 190 (SEQ ID NO: 190), FIG. 192 (SEQ ID NO: 192), FIG. 194 (SEQ ID NO: 194), FIG. 196 (SEQ ID NO: 196), FIG. 198 (SEQ ID NO: 198), FIG. 200 (SEQ ID NO: 200), FIG. 202 (SEQ ID NO: 202), FIG. 204 (SEQ ID NO: 204), FIG. 206 (SEQ ID NO: 206), FIG. 208 (SEQ ID NO: 208), FIG. 210 (SEQ ID NO: 210), FIG. 212 (SEQ ID NO: 212), FIG. 214 (SEQ ID NO: 214), FIG. 216 (SEQ ID NO: 216), FIG. 218 (SEQ ID NO: 218), FIG. 220 (SEQ ID NO: 220), FIG. 222 (SEQ ID NO: 222), FIG. 224 (SEQ ID NO: 224), FIG. 226 (SEQ ID NO: 226), FIG. 228 (SEQ ID NO: 228), FIG. 230 (SEQ ID NO: 230), FIG. 232 (SEQ ID NO: 232), FIG. 234 (SEQ ID NO: 234), FIG. 236 (SEQ ID NO: 236), FIG. 238 (SEQ ID NO: 238), FIG. 240 (SEQ ID NO: 240), FIG. 242 (SEQ ID NO: 242), FIG. 244 (SEQ ID NO: 244), FIG. 246 (SEQ ID NO: 246), FIG. 248 (SEQ ID NO: 248), FIG. 250 (SEQ ID NO: 250), FIG. 252 (SEQ ID NO: 252), FIG. 254 (SEQ ID NO: 254), FIG. 256 (SEQ ID NO: 256), FIG. 258 (SEQ ID NO: 258), FIG. 260 (SEQ ID NO: 260), FIG. 262 (SEQ ID NO: 262), FIG. 264 (SEQ ID NO: 264), FIG. 266 (SEQ ID NO: 266), FIG. 268 (SEQ ID NO: 268), FIG. 270 (SEQ ID NO: 270), FIG. 272 (SEQ ID NO: 272), FIG. 274 (SEQ ID NO: 274), FIG. 276 (SEQ ID NO: 276), FIG. 278 (SEQ ID NO: 278), FIG. 280 (SEQ ID NO: 280), FIG. 282 (SEQ ID NO: 282), FIG. 284 (SEQ ID NO: 284), FIG. 286 (SEQ ID NO: 286), FIG. 288 (SEQ ID NO: 288), FIG. 290 (SEQ ID NO: 290), FIG. 292 (SEQ ID NO: 292), FIG. 294 (SEQ ID NO: 294), FIG. 296 (SEQ ID NO: 296), FIG. 298 (SEQ ID NO: 298), FIG. 300 (SEQ ID NO: 300), FIG. 302 (SEQ ID NO: 302), FIG. 304 (SEQ ID NO: 304), FIG. 306 (SEQ ID NO: 306), FIG. 308 (SEQ ID NO: 308), FIG. 310 (SEQ ID NO: 310), FIG. 312 (SEQ ID NO: 312), FIG. 314 (SEQ ID NO: 314), FIG. 316 (SEQ ID NO: 316), FIG. 318 (SEQ ID NO: 318), FIG. 320 (SEQ ID NO: 320), FIG. 322 (SEQ ID NO: 322), FIG. 324 (SEQ ID NO: 324), FIG. 326 (SEQ ID NO: 326), FIG. 328 (SEQ ID NO: 328), FIG. 330 (SEQ ID NO: 330), FIG. 332 (SEQ ID NO: 332), FIG. 334 (SEQ ID NO: 334), FIG. 336 (SEQ ID NO: 336), FIG. 338 (SEQ ID NO: 338), FIG. 340 (SEQ ID NO: 340), FIG. 342 (SEQ ID NO: 342), FIG. 344 (SEQ ID NO: 344), FIG. 346 (SEQ ID NO: 346), FIG. 348 (SEQ ID NO: 348), FIG. 350 (SEQ ID NO: 350), FIG. 352 (SEQ ID NO: 352), FIG. 354 (SEQ ID NO: 354), FIG. 356 (SEQ ID NO: 356), FIG. 358 (SEQ ID NO: 358), FIG. 360 (SEQ ID NO: 360), FIG. 362 (SEQ ID NO: 362), FIG. 364 (SEQ ID NO: 364), FIG. 366 (SEQ ID NO: 366), FIG. 368 (SEQ ID NO: 368), FIG. 370 (SEQ ID NO: 370), FIG. 372 (SEQ ID NO: 372), FIG. 374 (SEQ ID NO: 374), FIG. 376 (SEQ ID NO: 376), FIG. 378 (SEQ ID NO: 378), FIG. 380 (SEQ ID NO: 380), FIG. 382 (SEQ ID NO: 382), FIG. 384 (SEQ ID NO: 384), FIG. 386 (SEQ ID NO: 386), FIG. 388 (SEQ ID NO: 388), FIG. 390 (SEQ ID NO: 390), FIG. 392 (SEQ ID NO: 392), FIG. 394 (SEQ ID NO: 394), FIG. 396 (SEQ ID NO: 396), FIG. 398 (SEQ ID NO: 398), FIG. 400 (SEQ ID NO: 400), FIG. 402 (SEQ ID NO: 402), FIG. 404 (SEQ ID NO: 404), FIG. 406 (SEQ ID NO: 406), FIG. 408 (SEQ ID NO: 408), FIG. 410 (SEQ ID NO: 410), FIG. 412 (SEQ ID NO: 412), FIG. 414 (SEQ ID NO: 414), FIG. 416 (SEQ ID NO: 416), FIG. 418 (SEQ ID NO: 418), FIG. 420 (SEQ ID NO: 420), FIG. 422 (SEQ ID NO: 422), FIG. 424 (SEQ ID NO: 424), FIG. 426 (SEQ ID NO: 426), FIG. 428 (SEQ ID NO: 428), FIG. 430 (SEQ ID NO: 430), FIG. 432 (SEQ ID NO: 432), FIG. 434 (SEQ ID NO: 434), FIG. 436 (SEQ ID NO: 436), FIG. 438 (SEQ ID NO: 438), FIG. 440 (SEQ ID NO: 440), FIG. 442 (SEQ ID NO: 442), FIG. 444 (SEQ ID NO: 444), FIG. 446 (SEQ ID NO: 446), FIG. 448 (SEQ ID NO: 448), FIG. 450 (SEQ ID NO: 450), FIG. 452 (SEQ ID NO: 452), FIG. 454 (SEQ ID NO: 454), FIG. 456 (SEQ ID NO: 456), FIG. 458 (SEQ ID NO: 458), FIG. 460 (SEQ ID NO: 460), FIG. 462 (SEQ ID NO: 462), FIG. 464 (SEQ ID NO: 464), FIG. 466 (SEQ ID NO: 466), FIG. 468 (SEQ ID NO: 468), FIG. 470 (SEQ ID NO: 470), FIG. 472 (SEQ ID NO: 472), FIG. 474 (SEQ ID NO: 474), FIG. 476 (SEQ ID NO: 476), FIG. 478 (SEQ ID NO: 478), FIG. 480 (SEQ ID NO: 480), FIG. 482 (SEQ ID NO: 482), FIG. 484 (SEQ ID NO: 484), FIG. 486 (SEQ ID NO: 486), FIG. 488 (SEQ ID NO: 488), FIG. 490 (SEQ ID NO: 490), FIG. 492 (SEQ ID NO: 492), FIG. 494 (SEQ ID NO: 494), FIG. 496 (SEQ ID NO: 496), FIG. 498 (SEQ ID NO: 498), FIG. 500 (SEQ ID NO: 500), FIG. 502 (SEQ ID NO: 502), FIG. 504 (SEQ ID NO: 504), FIG. 506 (SEQ ID NO: 506), FIG. 508 (SEQ ID NO: 508), FIG. 510 (SEQ ID NO: 510), FIG. 512 (SEQ ID NO: 512), FIG. 514 (SEQ ID NO: 514), FIG. 516 (SEQ ID NO: 516), FIG. 518 (SEQ ID NO: 518), FIG. 520 (SEQ ID NO: 520), FIG. 522 (SEQ ID NO: 522), FIG. 524 (SEQ ID NO: 524), FIG. 526 (SEQ ID NO: 526), FIG. 528 (SEQ ID NO: 528), FIG. 530 (SEQ ID NO: 530), FIG. 532 (SEQ ID NO: 532), FIG. 534 (SEQ ID NO: 534), FIG. 536 (SEQ ID NO: 536), FIG. 538 (SEQ ID NO: 538), FIG. 540 (SEQ ID NO: 540), FIG. 542 (SEQ ID NO: 542), FIG. 544 (SEQ ID NO: 544), FIG. 546 (SEQ ID NO: 546), FIG. 548 (SEQ ID NO: 548), FIG. 550 (SEQ ID NO: 550), FIG. 552 (SEQ ID NO: 552), FIG. 554 (SEQ ID NO: 554), FIG. 556 (SEQ ID NO: 556), FIG. 558 (SEQ ID NO: 558), FIG. 560 (SEQ ID NO: 560), FIG. 562 (SEQ ID NO: 562), FIG. 564 (SEQ ID NO: 564), FIG. 566 (SEQ ID NO: 566), FIG. 568 (SEQ ID NO: 568), FIG. 570 (SEQ ID NO: 570), FIG. 572 (SEQ ID NO: 572), FIG. 574 (SEQ ID NO: 574), FIG. 576 (SEQ ID NO: 576), FIG. 578 (SEQ ID NO: 578), FIG. 580 (SEQ ID NO: 580), FIG. 582 (SEQ ID NO: 582), FIG. 584 (SEQ ID NO: 584), FIG. 586 (SEQ ID NO: 586), FIG. 588 (SEQ ID NO: 588), FIG. 590 (SEQ ID NO: 590), FIG. 592 (SEQ ID NO: 592), FIG. 594 (SEQ ID NO: 594), FIG. 596 (SEQ ID NO: 596), FIG. 598 (SEQ ID NO: 598), FIG. 600 (SEQ ID NO: 600), FIG. 602 (SEQ ID NO: 602), FIG. 604 (SEQ ID NO: 604), FIG. 606 (SEQ ID NO: 606), FIG. 608 (SEQ ID NO: 608), or FIG. 610 (SEQ ID NO: 610), lacking its associated signal peptide.
20. A method for stimulating the release of TNF-α from human blood, said method comprising contacting said blood with a PRO1079, PRO827, PRO791, PRO1131, PRO1316, PRO1183, PRO1343, PRO1760, PRO1567 or PRO4333 polypeptide, wherein the release of TNF-α from said blood is stimulated.
21. A method for stimulating the proliferation or differentiation of chondrocyte cells, said method comprising contacting said cells with a PRO6029 polypeptide, wherein the proliferation or differentiation of said cells is stimulated.
22. A method for detecting the presence of tumor in an mammal, said method comprising comparing the level of expression of any PRO polypeptide shown in Table 8 in (a) a test sample of cells taken from said mammal and (b) a control sample of normal cells of the same cell type, wherein a higher level of expression of said PRO polypeptide in the test sample as compared to the control sample is indicative of the presence of tumor in said mammal.
23. The method ofclaim 22, wherein said tumor is adrenal tumor, lung tumor, colon tumor, breast tumor, prostate tumor, rectal tumor, cervical tumor or liver tumor.
24. An oligonucleotide probe derived from any of the nucleotide sequences shown in the accompanying figures.
US10/205,5081998-06-102002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the sameAbandonedUS20030104554A1 (en)

Priority Applications (1)

Application NumberPriority DateFiling DateTitle
US10/205,508US20030104554A1 (en)1998-06-102002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same

Applications Claiming Priority (5)

Application NumberPriority DateFiling DateTitle
US8882698P1998-06-101998-06-10
PCT/US2000/008439WO2000073454A1 (en)1999-06-022000-03-30Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/006520WO2001068848A2 (en)2000-03-012001-02-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/052,586US20020127584A1 (en)1997-09-182002-01-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,508US20030104554A1 (en)1998-06-102002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same

Related Parent Applications (1)

Application NumberTitlePriority DateFiling Date
US10/052,586ContinuationUS20020127584A1 (en)1997-09-152002-01-15Secreted and transmembrane polypeptides and nucleic acids encoding the same

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US20030104554A1true US20030104554A1 (en)2003-06-05

Family

ID=21978554

Family Applications (290)

Application NumberTitlePriority DateFiling Date
US10/176,760Expired - LifetimeUS7339033B2 (en)1998-06-262002-06-21Pro1481
US10/176,984AbandonedUS20030166132A1 (en)1998-08-262002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,526AbandonedUS20030100061A1 (en)1998-06-262002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,542AbandonedUS20030036121A1 (en)1998-06-262002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,544AbandonedUS20030032119A1 (en)1998-06-262002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,011AbandonedUS20030068682A1 (en)1998-06-262002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,640Expired - LifetimeUS7271250B2 (en)1998-06-262002-06-27PRO1757 antibodies
US10/184,645Expired - LifetimeUS7291718B2 (en)1998-06-262002-06-28PRO1758 antibodies
US10/184,621AbandonedUS20030054455A1 (en)1998-06-262002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,634AbandonedUS20030068684A1 (en)1998-06-262002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,658AbandonedUS20030027281A1 (en)1998-06-262002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,591Expired - LifetimeUS7709603B2 (en)1998-09-292002-07-01PRO1190 polypeptides
US10/187,750AbandonedUS20030049740A1 (en)2000-03-012002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,588Expired - LifetimeUS7351795B2 (en)1998-06-262002-07-01PRO19563 polypeptides
US10/187,740AbandonedUS20030064443A1 (en)1998-10-262002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,739Expired - LifetimeUS7291706B2 (en)1998-06-262002-07-01PRO4352 polypeptides
US10/187,599Expired - LifetimeUS7355013B2 (en)2000-06-052002-07-01PRO6017 antibodies
US10/187,888AbandonedUS20030073175A1 (en)2000-03-032002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,752AbandonedUS20030054457A1 (en)1999-04-052002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,755Expired - LifetimeUS7312309B2 (en)2000-06-052002-07-01PRO6017 polypeptides
US10/187,594Expired - LifetimeUS7294335B2 (en)1998-06-262002-07-01PRO19645 antibodies
US10/187,595Expired - Fee RelatedUS7563867B2 (en)1999-03-232002-07-01PRO4356 polypeptides
US10/187,748AbandonedUS20030068687A1 (en)2000-03-032002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,592Expired - LifetimeUS7314913B2 (en)2000-03-032002-07-01PRO1891 polypeptides
US10/187,742AbandonedUS20030068686A1 (en)1998-07-022002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,738AbandonedUS20030064442A1 (en)1998-09-292002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,771AbandonedUS20030068689A1 (en)2000-06-052002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,883AbandonedUS20030064444A1 (en)1998-10-012002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,780Expired - LifetimeUS7268217B2 (en)1998-06-262002-07-02PRO4421 polypeptides
US10/188,766Expired - LifetimeUS7351804B2 (en)1998-06-262002-07-02Antibodies against PRO4421
US10/187,885AbandonedUS20030032138A1 (en)1998-06-242002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,749AbandonedUS20030153036A1 (en)1998-06-102002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,603AbandonedUS20030036146A1 (en)1998-06-262002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,008AbandonedUS20030068693A1 (en)2000-06-052002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,012Expired - LifetimeUS7304134B2 (en)2000-09-152002-07-09PRO9742 polypeptides
US10/192,015AbandonedUS20030049742A1 (en)2000-06-052002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,007Expired - Fee RelatedUS7317083B2 (en)2000-03-032002-07-09PRO4501 polypeptides
US10/192,014Expired - LifetimeUS7312315B2 (en)2000-09-152002-07-09PRO9742 antibodies
US10/192,011AbandonedUS20030207395A1 (en)1998-03-272002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,006AbandonedUS20030068692A1 (en)2000-06-052002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,009AbandonedUS20030068694A1 (en)2000-06-052002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,016AbandonedUS20030068697A1 (en)2000-06-052002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,394Expired - LifetimeUS7390886B2 (en)2000-09-152002-07-11PRO9822 antibodies
US10/194,463AbandonedUS20030064447A1 (en)2000-06-052002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,486AbandonedUS20030207396A1 (en)2000-06-052002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,457AbandonedUS20030153037A1 (en)2000-09-152002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,459Expired - LifetimeUS7307144B2 (en)2000-06-052002-07-11PRO 6493 polypeptides
US10/194,488AbandonedUS20030068704A1 (en)2000-06-052002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,395Expired - Fee RelatedUS7326773B2 (en)2000-06-052002-07-11PRO6493 antibodies
US10/194,460AbandonedUS20030064446A1 (en)2000-09-152002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,485Expired - LifetimeUS7449549B2 (en)2000-09-152002-07-11PRO9822 polypeptides
US10/194,425AbandonedUS20030049744A1 (en)2000-06-052002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,363AbandonedUS20030064445A1 (en)2000-06-052002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,424Expired - LifetimeUS7335730B2 (en)2000-06-052002-07-12PRO7436 polypeptides
US10/194,359Expired - Fee RelatedUS8063186B2 (en)2000-06-052002-07-12Antibodies to PRO7436 polypeptides
US10/194,361AbandonedUS20030036161A1 (en)1998-06-262002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,360AbandonedUS20030073176A1 (en)2000-06-052002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,484AbandonedUS20030064448A1 (en)2000-09-152002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,458AbandonedUS20030068702A1 (en)2000-06-052002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,487Expired - LifetimeUS7427667B2 (en)2000-09-152002-07-12PRO9835 antibodies
US10/194,365Expired - LifetimeUS7381791B2 (en)1998-06-262002-07-12PRO9739 polypeptides
US10/194,456AbandonedUS20030059879A1 (en)2000-09-152002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,362AbandonedUS20030068698A1 (en)2000-06-052002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,364Expired - Fee RelatedUS7314918B2 (en)2000-06-052002-07-12PRO6246 antibodies
US10/194,423Expired - Fee RelatedUS7339025B2 (en)1998-06-262002-07-12PRO6246 polypeptides
US10/194,461AbandonedUS20030054459A1 (en)1998-06-262002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,884AbandonedUS20030064449A1 (en)2000-09-152002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,900Expired - LifetimeUS7351789B2 (en)2000-03-142002-07-15PRO19624 polypeptides
US10/195,901AbandonedUS20030036165A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,898AbandonedUS20030071834A1 (en)2000-04-252002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,894AbandonedUS20030043176A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,896AbandonedUS20030063112A1 (en)2000-04-252002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,902AbandonedUS20030038826A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,899AbandonedUS20030049747A1 (en)2000-04-182002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,889Expired - LifetimeUS7534856B2 (en)1998-06-262002-07-15PRO19624 antibodies
US10/195,891Expired - LifetimeUS7304135B2 (en)2000-09-152002-07-15PRO9859 polypeptides
US10/195,892Expired - LifetimeUS7385033B2 (en)1998-06-262002-07-15PRO12970 polypeptides
US10/195,893AbandonedUS20030206188A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,886AbandonedUS20030068705A1 (en)2000-09-152002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,883AbandonedUS20060073544A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,887Expired - LifetimeUS7375179B2 (en)2000-04-042002-07-15PRO19680 polypeptides
US10/195,895Expired - LifetimeUS7378487B2 (en)2000-04-112002-07-15PRO19675 polypeptides
US10/195,890Expired - LifetimeUS7309776B2 (en)2000-03-142002-07-15PRO12970 antibodies
US10/195,888AbandonedUS20060073545A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,885Expired - LifetimeUS7399824B2 (en)2000-04-042002-07-15PRO19680 antibodies
US10/196,761AbandonedUS20030068710A1 (en)2000-04-182002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,749Expired - LifetimeUS7312316B2 (en)2000-03-212002-07-16PRO16090 antibodies
US10/196,756Expired - LifetimeUS7304145B2 (en)1998-06-262002-07-16PRO19646 antibodies
US10/196,760Expired - LifetimeUS7408034B2 (en)1998-06-262002-07-16PRO20025 polypeptides
US10/196,750Expired - LifetimeUS7288628B2 (en)2000-05-032002-07-16PRO20088 polypeptides
US10/196,753Expired - LifetimeUS7371815B2 (en)2000-03-292002-07-16PRO19644 polypeptides
US10/196,755AbandonedUS20030064451A1 (en)2000-03-212002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,757Expired - LifetimeUS7375196B2 (en)2000-04-252002-07-16PRO19814 antibodies
US10/196,748AbandonedUS20030049748A1 (en)2000-04-112002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,751Expired - LifetimeUS7309771B2 (en)2000-04-112002-07-16PRO19646 polypeptides
US10/196,746Expired - LifetimeUS7345147B2 (en)1998-05-282002-07-16PRO16089 polypeptides
US10/196,743AbandonedUS20030038827A1 (en)1998-06-262002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,762AbandonedUS20030040078A1 (en)1998-06-262002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,758AbandonedUS20030059880A1 (en)2000-03-292002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,752AbandonedUS20030068708A1 (en)1998-10-302002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,747AbandonedUS20030162250A1 (en)2000-04-112002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,754Expired - LifetimeUS7282561B2 (en)2000-03-212002-07-16PRO16090 polypeptides
US10/196,744Expired - Fee RelatedUS7465786B2 (en)1998-10-302002-07-16PRO1801 polypeptides
US10/196,759AbandonedUS20030071835A1 (en)1998-06-262002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/197,703AbandonedUS20030068715A1 (en)1998-06-042002-07-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/197,699AbandonedUS20030049750A1 (en)1998-06-022002-07-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/197,707AbandonedUS20030054464A1 (en)1998-06-042002-07-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/197,694AbandonedUS20030054462A1 (en)1997-11-212002-07-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/197,698AbandonedUS20030068714A1 (en)1998-10-272002-07-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,666AbandonedUS20030049765A1 (en)1998-06-052002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,315AbandonedUS20030068725A1 (en)1998-06-052002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,463AbandonedUS20030215910A1 (en)1998-06-092002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,766AbandonedUS20030064455A1 (en)1998-05-282002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,307AbandonedUS20030068723A1 (en)1998-06-042002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,769AbandonedUS20030049757A1 (en)1998-05-152002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,458AbandonedUS20030054467A1 (en)1998-06-252002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,456AbandonedUS20030064459A1 (en)1998-06-252002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,461AbandonedUS20030068730A1 (en)1998-08-172002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,301AbandonedUS20030068722A1 (en)1998-05-282002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,309AbandonedUS20030064457A1 (en)1998-05-152002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,313AbandonedUS20030064458A1 (en)1998-08-262002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,303AbandonedUS20030054465A1 (en)1998-06-242002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,306AbandonedUS20030049759A1 (en)1998-09-302002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,314AbandonedUS20030049762A1 (en)1998-09-232002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,669AbandonedUS20030049766A1 (en)1998-06-052002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,457AbandonedUS20030068727A1 (en)1998-09-182002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,771AbandonedUS20030092122A1 (en)1998-08-262002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,462AbandonedUS20030054468A1 (en)1998-06-262002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,302AbandonedUS20030073179A1 (en)1998-06-242002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,768AbandonedUS20030049756A1 (en)1998-06-262002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,312AbandonedUS20030068724A1 (en)1998-05-222002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,318AbandonedUS20030054466A1 (en)1998-06-252002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,316AbandonedUS20030068726A1 (en)1998-06-262002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,762AbandonedUS20030068719A1 (en)1998-05-152002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,757AbandonedUS20030068717A1 (en)1998-09-012002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,670AbandonedUS20040033560A1 (en)2001-02-282002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,305AbandonedUS20030049758A1 (en)1998-06-102002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,459AbandonedUS20030068728A1 (en)1998-09-162002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,304AbandonedUS20030064456A1 (en)1998-10-282002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,767AbandonedUS20030068721A1 (en)2001-02-282002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,770AbandonedUS20030059882A1 (en)1998-05-152002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,311AbandonedUS20030049761A1 (en)1998-06-252002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,310AbandonedUS20030049760A1 (en)1998-06-052002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,308AbandonedUS20030059883A1 (en)1998-09-292002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,317AbandonedUS20030049763A1 (en)1998-09-292002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,532AbandonedUS20030068736A1 (en)1998-10-262002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,530AbandonedUS20030054474A1 (en)1998-06-222002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,324AbandonedUS20030054469A1 (en)1998-09-092002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,327AbandonedUS20030077736A1 (en)1998-11-172002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,771AbandonedUS20030068740A1 (en)1998-08-262002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,528AbandonedUS20030054472A1 (en)1998-08-182002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,321AbandonedUS20030068733A1 (en)1998-11-032002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,534AbandonedUS20030049767A1 (en)2000-03-032002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,328AbandonedUS20030054470A1 (en)1998-06-242002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,325AbandonedUS20030096357A1 (en)1998-07-022002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,329AbandonedUS20030064460A1 (en)1998-09-022002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,322AbandonedUS20030068734A1 (en)1998-06-102002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,527AbandonedUS20030054471A1 (en)1998-11-182002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,323AbandonedUS20030073180A1 (en)1998-06-052002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,770AbandonedUS20030049768A1 (en)1998-09-022002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,529AbandonedUS20030054473A1 (en)1998-06-162002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,533AbandonedUS20030068737A1 (en)1998-06-182002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,326AbandonedUS20030068735A1 (en)1998-08-042002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,857AbandonedUS20030104549A1 (en)1998-09-232002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,413AbandonedUS20030104550A1 (en)1998-09-302002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,410AbandonedUS20030068742A1 (en)1998-09-172002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,476AbandonedUS20030049773A1 (en)1998-10-022002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,470AbandonedUS20030049772A1 (en)1998-10-142002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,772AbandonedUS20030113843A1 (en)1998-10-222002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,471AbandonedUS20030215911A1 (en)1998-10-072002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,854AbandonedUS20030068741A1 (en)1998-11-032002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,473AbandonedUS20030068743A1 (en)1998-10-272002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,853AbandonedUS20040053358A1 (en)1998-11-182002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,858AbandonedUS20040038337A1 (en)1998-11-172002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,409AbandonedUS20030054476A1 (en)1998-06-112002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,769Expired - Fee RelatedUS7087737B2 (en)1998-10-062002-07-23Pro1278 nucleic acids
US10/202,408AbandonedUS20030054475A1 (en)1998-09-182002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,411AbandonedUS20030054477A1 (en)1998-11-172002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,472AbandonedUS20030054478A1 (en)1998-06-112002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,474AbandonedUS20030068744A1 (en)1998-11-172002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,412AbandonedUS20030064461A1 (en)1998-10-282002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,475AbandonedUS20030180881A1 (en)1998-08-262002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,469AbandonedUS20030049771A1 (en)1998-10-292002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,855AbandonedUS20030049769A1 (en)1998-09-102002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,535AbandonedUS20030068738A1 (en)1998-10-082002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding tha same
US10/201,856AbandonedUS20030049770A1 (en)1998-10-272002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,502AbandonedUS20030054479A1 (en)1998-06-042002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,503AbandonedUS20030068745A1 (en)1998-06-172002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,510AbandonedUS20030073181A1 (en)1998-07-022002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,504AbandonedUS20030049778A1 (en)1998-10-282002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,512AbandonedUS20030068746A1 (en)1998-11-032002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,936AbandonedUS20030049776A1 (en)2000-05-222002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,935AbandonedUS20030049775A1 (en)1998-06-032002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,506AbandonedUS20030207399A1 (en)1998-10-282002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,511AbandonedUS20030054481A1 (en)1998-06-242002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,508AbandonedUS20030104554A1 (en)1998-06-102002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,507AbandonedUS20030054480A1 (en)1998-05-222002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,939AbandonedUS20030049777A1 (en)2000-04-112002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,941AbandonedUS20030096358A1 (en)1998-09-292002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,909AbandonedUS20030049783A1 (en)2000-03-032002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,891AbandonedUS20030073182A1 (en)2000-06-052002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,895AbandonedUS20030049780A1 (en)1999-03-232002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,897AbandonedUS20030059886A1 (en)2000-06-052002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,927AbandonedUS20030068764A1 (en)1999-08-032002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,911AbandonedUS20030068755A1 (en)2000-03-012002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,914AbandonedUS20030068758A1 (en)2000-03-012002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,904AbandonedUS20030073813A1 (en)1998-06-262002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,893AbandonedUS20030059885A1 (en)2000-03-032002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,903AbandonedUS20030068752A1 (en)2000-06-052002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,902AbandonedUS20030054482A1 (en)2000-04-042002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,928AbandonedUS20030064465A1 (en)1998-10-262002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,905AbandonedUS20030104555A1 (en)1998-10-012002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,894AbandonedUS20030068748A1 (en)2000-06-052002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,896AbandonedUS20030068749A1 (en)1998-10-012002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,913AbandonedUS20030068757A1 (en)1999-04-052002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,907AbandonedUS20030119110A1 (en)2000-06-052002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,908AbandonedUS20030045700A1 (en)2000-03-032002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,926AbandonedUS20030068763A1 (en)1999-07-202002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,909AbandonedUS20030068753A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,915AbandonedUS20040029221A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,901AbandonedUS20030068751A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,919AbandonedUS20030064462A1 (en)2000-09-152002-07-26Secreted and transmembrance polypeptides and nucleic acids encoding the same
US10/205,892AbandonedUS20030068747A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,923AbandonedUS20030068761A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,890AbandonedUS20040048334A1 (en)2000-09-152002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,912AbandonedUS20030068756A1 (en)2000-09-152002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,921AbandonedUS20030068760A1 (en)2000-09-152002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,918AbandonedUS20030104556A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,900AbandonedUS20030049782A1 (en)2000-03-032002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,898AbandonedUS20030068750A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,907AbandonedUS20030054483A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,899AbandonedUS20030049781A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,917AbandonedUS20030073183A1 (en)2000-09-152002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,924AbandonedUS20030064464A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,916AbandonedUS20040091959A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,920AbandonedUS20030068759A1 (en)2000-09-152002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,910AbandonedUS20030068754A1 (en)2000-03-212002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,910AbandonedUS20030096359A1 (en)2000-09-152002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,925AbandonedUS20030068762A1 (en)2000-06-052002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,922AbandonedUS20030064463A1 (en)2000-09-152002-07-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,916Expired - Fee RelatedUS7189838B2 (en)2000-09-152002-07-29PRO9834 nucleic acids
US10/207,925AbandonedUS20030068770A1 (en)2000-03-292002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,919AbandonedUS20030068768A1 (en)2000-03-292002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/208,023AbandonedUS20030068773A1 (en)2000-09-152002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,920AbandonedUS20030068769A1 (en)2000-04-182002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/208,030AbandonedUS20030068776A1 (en)2000-04-112002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,924AbandonedUS20030073185A1 (en)2000-04-182002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,917AbandonedUS20030068766A1 (en)2000-04-252002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,922AbandonedUS20030064468A1 (en)2000-04-112002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/208,028AbandonedUS20030073186A1 (en)2000-04-042002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,918AbandonedUS20030068767A1 (en)2000-03-142002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/208,025AbandonedUS20030104557A1 (en)1999-03-232002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/208,024AbandonedUS20040048335A1 (en)2000-09-152002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/208,027AbandonedUS20030064469A1 (en)2000-04-112002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/208,026AbandonedUS20030068774A1 (en)2000-05-032002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,923AbandonedUS20030073184A1 (en)2000-09-152002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,915AbandonedUS20030215912A1 (en)2000-04-252002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/208,021AbandonedUS20030068771A1 (en)2000-03-142002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/208,029AbandonedUS20030068775A1 (en)1999-03-232002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,914AbandonedUS20030064466A1 (en)1998-10-302002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/207,921AbandonedUS20030064467A1 (en)2000-03-212002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/208,022AbandonedUS20030068772A1 (en)2000-03-212002-07-29Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/026,279AbandonedUS20050176041A1 (en)1998-06-042004-12-30Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/030,464AbandonedUS20050214819A1 (en)1998-06-252005-01-05Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/036,582AbandonedUS20050164266A1 (en)1998-06-052005-01-13Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/038,549AbandonedUS20060246461A1 (en)1998-10-272005-01-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/039,623AbandonedUS20060068404A1 (en)1998-08-262005-01-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/040,638AbandonedUS20050244852A1 (en)1998-06-252005-01-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/042,889AbandonedUS20050272058A1 (en)1998-09-022005-01-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/067,573AbandonedUS20050260622A1 (en)1998-05-282005-02-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/078,280AbandonedUS20050250136A1 (en)1999-06-022005-03-10Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/084,458AbandonedUS20050260632A1 (en)1998-06-242005-03-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/084,792AbandonedUS20060051777A1 (en)1998-04-212005-03-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/090,729AbandonedUS20060068413A1 (en)1998-09-182005-03-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/122,524AbandonedUS20060003355A1 (en)1998-08-172005-05-04Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/124,327AbandonedUS20050266461A1 (en)1997-11-212005-05-06Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/150,881AbandonedUS20060084084A1 (en)1998-07-022005-06-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/150,758AbandonedUS20060051784A1 (en)1998-07-022005-06-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/150,463AbandonedUS20060051783A1 (en)1998-08-262005-06-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/151,868AbandonedUS20060051785A1 (en)1998-06-182005-06-13Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/172,714AbandonedUS20060019287A1 (en)1998-06-052005-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/189,442AbandonedUS20060246465A1 (en)1998-06-042005-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/194,054AbandonedUS20060194219A1 (en)1998-06-242005-07-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/199,816AbandonedUS20060068423A1 (en)2000-06-052005-08-08Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/216,875AbandonedUS20060029966A1 (en)1998-06-162005-08-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/258,349Expired - LifetimeUS7470774B2 (en)1998-09-302005-10-24Anti-pro1477 antibodies
US11/258,348Expired - Fee RelatedUS7462692B2 (en)1998-09-302005-10-24PRO1477 polypeptides
US11/323,117AbandonedUS20070092941A1 (en)1998-09-162005-12-29PRO1298 polypeptides
US11/367,172AbandonedUS20060257897A1 (en)1998-10-282006-03-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US12/319,421Expired - Fee RelatedUS7786272B2 (en)1998-03-272009-01-06Antibodies to PRO352

Family Applications Before (195)

Application NumberTitlePriority DateFiling Date
US10/176,760Expired - LifetimeUS7339033B2 (en)1998-06-262002-06-21Pro1481
US10/176,984AbandonedUS20030166132A1 (en)1998-08-262002-06-21Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/179,526AbandonedUS20030100061A1 (en)1998-06-262002-06-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,542AbandonedUS20030036121A1 (en)1998-06-262002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/180,544AbandonedUS20030032119A1 (en)1998-06-262002-06-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/183,011AbandonedUS20030068682A1 (en)1998-06-262002-06-26Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,640Expired - LifetimeUS7271250B2 (en)1998-06-262002-06-27PRO1757 antibodies
US10/184,645Expired - LifetimeUS7291718B2 (en)1998-06-262002-06-28PRO1758 antibodies
US10/184,621AbandonedUS20030054455A1 (en)1998-06-262002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,634AbandonedUS20030068684A1 (en)1998-06-262002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/184,658AbandonedUS20030027281A1 (en)1998-06-262002-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,591Expired - LifetimeUS7709603B2 (en)1998-09-292002-07-01PRO1190 polypeptides
US10/187,750AbandonedUS20030049740A1 (en)2000-03-012002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,588Expired - LifetimeUS7351795B2 (en)1998-06-262002-07-01PRO19563 polypeptides
US10/187,740AbandonedUS20030064443A1 (en)1998-10-262002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,739Expired - LifetimeUS7291706B2 (en)1998-06-262002-07-01PRO4352 polypeptides
US10/187,599Expired - LifetimeUS7355013B2 (en)2000-06-052002-07-01PRO6017 antibodies
US10/187,888AbandonedUS20030073175A1 (en)2000-03-032002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,752AbandonedUS20030054457A1 (en)1999-04-052002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,755Expired - LifetimeUS7312309B2 (en)2000-06-052002-07-01PRO6017 polypeptides
US10/187,594Expired - LifetimeUS7294335B2 (en)1998-06-262002-07-01PRO19645 antibodies
US10/187,595Expired - Fee RelatedUS7563867B2 (en)1999-03-232002-07-01PRO4356 polypeptides
US10/187,748AbandonedUS20030068687A1 (en)2000-03-032002-07-01Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,592Expired - LifetimeUS7314913B2 (en)2000-03-032002-07-01PRO1891 polypeptides
US10/187,742AbandonedUS20030068686A1 (en)1998-07-022002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,738AbandonedUS20030064442A1 (en)1998-09-292002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,771AbandonedUS20030068689A1 (en)2000-06-052002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,883AbandonedUS20030064444A1 (en)1998-10-012002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/188,780Expired - LifetimeUS7268217B2 (en)1998-06-262002-07-02PRO4421 polypeptides
US10/188,766Expired - LifetimeUS7351804B2 (en)1998-06-262002-07-02Antibodies against PRO4421
US10/187,885AbandonedUS20030032138A1 (en)1998-06-242002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,749AbandonedUS20030153036A1 (en)1998-06-102002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/187,603AbandonedUS20030036146A1 (en)1998-06-262002-07-02Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,008AbandonedUS20030068693A1 (en)2000-06-052002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,012Expired - LifetimeUS7304134B2 (en)2000-09-152002-07-09PRO9742 polypeptides
US10/192,015AbandonedUS20030049742A1 (en)2000-06-052002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,007Expired - Fee RelatedUS7317083B2 (en)2000-03-032002-07-09PRO4501 polypeptides
US10/192,014Expired - LifetimeUS7312315B2 (en)2000-09-152002-07-09PRO9742 antibodies
US10/192,011AbandonedUS20030207395A1 (en)1998-03-272002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,006AbandonedUS20030068692A1 (en)2000-06-052002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,009AbandonedUS20030068694A1 (en)2000-06-052002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/192,016AbandonedUS20030068697A1 (en)2000-06-052002-07-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,394Expired - LifetimeUS7390886B2 (en)2000-09-152002-07-11PRO9822 antibodies
US10/194,463AbandonedUS20030064447A1 (en)2000-06-052002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,486AbandonedUS20030207396A1 (en)2000-06-052002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,457AbandonedUS20030153037A1 (en)2000-09-152002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,459Expired - LifetimeUS7307144B2 (en)2000-06-052002-07-11PRO 6493 polypeptides
US10/194,488AbandonedUS20030068704A1 (en)2000-06-052002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,395Expired - Fee RelatedUS7326773B2 (en)2000-06-052002-07-11PRO6493 antibodies
US10/194,460AbandonedUS20030064446A1 (en)2000-09-152002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,485Expired - LifetimeUS7449549B2 (en)2000-09-152002-07-11PRO9822 polypeptides
US10/194,425AbandonedUS20030049744A1 (en)2000-06-052002-07-11Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,363AbandonedUS20030064445A1 (en)2000-06-052002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,424Expired - LifetimeUS7335730B2 (en)2000-06-052002-07-12PRO7436 polypeptides
US10/194,359Expired - Fee RelatedUS8063186B2 (en)2000-06-052002-07-12Antibodies to PRO7436 polypeptides
US10/194,361AbandonedUS20030036161A1 (en)1998-06-262002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,360AbandonedUS20030073176A1 (en)2000-06-052002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,484AbandonedUS20030064448A1 (en)2000-09-152002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,458AbandonedUS20030068702A1 (en)2000-06-052002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,487Expired - LifetimeUS7427667B2 (en)2000-09-152002-07-12PRO9835 antibodies
US10/194,365Expired - LifetimeUS7381791B2 (en)1998-06-262002-07-12PRO9739 polypeptides
US10/194,456AbandonedUS20030059879A1 (en)2000-09-152002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,362AbandonedUS20030068698A1 (en)2000-06-052002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/194,364Expired - Fee RelatedUS7314918B2 (en)2000-06-052002-07-12PRO6246 antibodies
US10/194,423Expired - Fee RelatedUS7339025B2 (en)1998-06-262002-07-12PRO6246 polypeptides
US10/194,461AbandonedUS20030054459A1 (en)1998-06-262002-07-12Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,884AbandonedUS20030064449A1 (en)2000-09-152002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,900Expired - LifetimeUS7351789B2 (en)2000-03-142002-07-15PRO19624 polypeptides
US10/195,901AbandonedUS20030036165A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,898AbandonedUS20030071834A1 (en)2000-04-252002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,894AbandonedUS20030043176A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,896AbandonedUS20030063112A1 (en)2000-04-252002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,902AbandonedUS20030038826A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,899AbandonedUS20030049747A1 (en)2000-04-182002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,889Expired - LifetimeUS7534856B2 (en)1998-06-262002-07-15PRO19624 antibodies
US10/195,891Expired - LifetimeUS7304135B2 (en)2000-09-152002-07-15PRO9859 polypeptides
US10/195,892Expired - LifetimeUS7385033B2 (en)1998-06-262002-07-15PRO12970 polypeptides
US10/195,893AbandonedUS20030206188A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,886AbandonedUS20030068705A1 (en)2000-09-152002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,883AbandonedUS20060073544A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,887Expired - LifetimeUS7375179B2 (en)2000-04-042002-07-15PRO19680 polypeptides
US10/195,895Expired - LifetimeUS7378487B2 (en)2000-04-112002-07-15PRO19675 polypeptides
US10/195,890Expired - LifetimeUS7309776B2 (en)2000-03-142002-07-15PRO12970 antibodies
US10/195,888AbandonedUS20060073545A1 (en)1998-06-262002-07-15Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/195,885Expired - LifetimeUS7399824B2 (en)2000-04-042002-07-15PRO19680 antibodies
US10/196,761AbandonedUS20030068710A1 (en)2000-04-182002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,749Expired - LifetimeUS7312316B2 (en)2000-03-212002-07-16PRO16090 antibodies
US10/196,756Expired - LifetimeUS7304145B2 (en)1998-06-262002-07-16PRO19646 antibodies
US10/196,760Expired - LifetimeUS7408034B2 (en)1998-06-262002-07-16PRO20025 polypeptides
US10/196,750Expired - LifetimeUS7288628B2 (en)2000-05-032002-07-16PRO20088 polypeptides
US10/196,753Expired - LifetimeUS7371815B2 (en)2000-03-292002-07-16PRO19644 polypeptides
US10/196,755AbandonedUS20030064451A1 (en)2000-03-212002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,757Expired - LifetimeUS7375196B2 (en)2000-04-252002-07-16PRO19814 antibodies
US10/196,748AbandonedUS20030049748A1 (en)2000-04-112002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,751Expired - LifetimeUS7309771B2 (en)2000-04-112002-07-16PRO19646 polypeptides
US10/196,746Expired - LifetimeUS7345147B2 (en)1998-05-282002-07-16PRO16089 polypeptides
US10/196,743AbandonedUS20030038827A1 (en)1998-06-262002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,762AbandonedUS20030040078A1 (en)1998-06-262002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,758AbandonedUS20030059880A1 (en)2000-03-292002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,752AbandonedUS20030068708A1 (en)1998-10-302002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,747AbandonedUS20030162250A1 (en)2000-04-112002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/196,754Expired - LifetimeUS7282561B2 (en)2000-03-212002-07-16PRO16090 polypeptides
US10/196,744Expired - Fee RelatedUS7465786B2 (en)1998-10-302002-07-16PRO1801 polypeptides
US10/196,759AbandonedUS20030071835A1 (en)1998-06-262002-07-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/197,703AbandonedUS20030068715A1 (en)1998-06-042002-07-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/197,699AbandonedUS20030049750A1 (en)1998-06-022002-07-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/197,707AbandonedUS20030054464A1 (en)1998-06-042002-07-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/197,694AbandonedUS20030054462A1 (en)1997-11-212002-07-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/197,698AbandonedUS20030068714A1 (en)1998-10-272002-07-17Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,666AbandonedUS20030049765A1 (en)1998-06-052002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,315AbandonedUS20030068725A1 (en)1998-06-052002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,463AbandonedUS20030215910A1 (en)1998-06-092002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,766AbandonedUS20030064455A1 (en)1998-05-282002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,307AbandonedUS20030068723A1 (en)1998-06-042002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,769AbandonedUS20030049757A1 (en)1998-05-152002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,458AbandonedUS20030054467A1 (en)1998-06-252002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,456AbandonedUS20030064459A1 (en)1998-06-252002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,461AbandonedUS20030068730A1 (en)1998-08-172002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,301AbandonedUS20030068722A1 (en)1998-05-282002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,309AbandonedUS20030064457A1 (en)1998-05-152002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,313AbandonedUS20030064458A1 (en)1998-08-262002-07-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,303AbandonedUS20030054465A1 (en)1998-06-242002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,306AbandonedUS20030049759A1 (en)1998-09-302002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,314AbandonedUS20030049762A1 (en)1998-09-232002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,669AbandonedUS20030049766A1 (en)1998-06-052002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,457AbandonedUS20030068727A1 (en)1998-09-182002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,771AbandonedUS20030092122A1 (en)1998-08-262002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,462AbandonedUS20030054468A1 (en)1998-06-262002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,302AbandonedUS20030073179A1 (en)1998-06-242002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,768AbandonedUS20030049756A1 (en)1998-06-262002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,312AbandonedUS20030068724A1 (en)1998-05-222002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,318AbandonedUS20030054466A1 (en)1998-06-252002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,316AbandonedUS20030068726A1 (en)1998-06-262002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,762AbandonedUS20030068719A1 (en)1998-05-152002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,757AbandonedUS20030068717A1 (en)1998-09-012002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,670AbandonedUS20040033560A1 (en)2001-02-282002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,305AbandonedUS20030049758A1 (en)1998-06-102002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,459AbandonedUS20030068728A1 (en)1998-09-162002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,304AbandonedUS20030064456A1 (en)1998-10-282002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,767AbandonedUS20030068721A1 (en)2001-02-282002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/198,770AbandonedUS20030059882A1 (en)1998-05-152002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,311AbandonedUS20030049761A1 (en)1998-06-252002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,310AbandonedUS20030049760A1 (en)1998-06-052002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,308AbandonedUS20030059883A1 (en)1998-09-292002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/199,317AbandonedUS20030049763A1 (en)1998-09-292002-07-19Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,532AbandonedUS20030068736A1 (en)1998-10-262002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,530AbandonedUS20030054474A1 (en)1998-06-222002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,324AbandonedUS20030054469A1 (en)1998-09-092002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,327AbandonedUS20030077736A1 (en)1998-11-172002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,771AbandonedUS20030068740A1 (en)1998-08-262002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,528AbandonedUS20030054472A1 (en)1998-08-182002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,321AbandonedUS20030068733A1 (en)1998-11-032002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,534AbandonedUS20030049767A1 (en)2000-03-032002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,328AbandonedUS20030054470A1 (en)1998-06-242002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,325AbandonedUS20030096357A1 (en)1998-07-022002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,329AbandonedUS20030064460A1 (en)1998-09-022002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,322AbandonedUS20030068734A1 (en)1998-06-102002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,527AbandonedUS20030054471A1 (en)1998-11-182002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,323AbandonedUS20030073180A1 (en)1998-06-052002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,770AbandonedUS20030049768A1 (en)1998-09-022002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,529AbandonedUS20030054473A1 (en)1998-06-162002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,533AbandonedUS20030068737A1 (en)1998-06-182002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,326AbandonedUS20030068735A1 (en)1998-08-042002-07-22Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,857AbandonedUS20030104549A1 (en)1998-09-232002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,413AbandonedUS20030104550A1 (en)1998-09-302002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,410AbandonedUS20030068742A1 (en)1998-09-172002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,476AbandonedUS20030049773A1 (en)1998-10-022002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,470AbandonedUS20030049772A1 (en)1998-10-142002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,772AbandonedUS20030113843A1 (en)1998-10-222002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,471AbandonedUS20030215911A1 (en)1998-10-072002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,854AbandonedUS20030068741A1 (en)1998-11-032002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,473AbandonedUS20030068743A1 (en)1998-10-272002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,853AbandonedUS20040053358A1 (en)1998-11-182002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,858AbandonedUS20040038337A1 (en)1998-11-172002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,409AbandonedUS20030054476A1 (en)1998-06-112002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,769Expired - Fee RelatedUS7087737B2 (en)1998-10-062002-07-23Pro1278 nucleic acids
US10/202,408AbandonedUS20030054475A1 (en)1998-09-182002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,411AbandonedUS20030054477A1 (en)1998-11-172002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,472AbandonedUS20030054478A1 (en)1998-06-112002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,474AbandonedUS20030068744A1 (en)1998-11-172002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,412AbandonedUS20030064461A1 (en)1998-10-282002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,475AbandonedUS20030180881A1 (en)1998-08-262002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,469AbandonedUS20030049771A1 (en)1998-10-292002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,855AbandonedUS20030049769A1 (en)1998-09-102002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/201,535AbandonedUS20030068738A1 (en)1998-10-082002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding tha same
US10/201,856AbandonedUS20030049770A1 (en)1998-10-272002-07-23Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,502AbandonedUS20030054479A1 (en)1998-06-042002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,503AbandonedUS20030068745A1 (en)1998-06-172002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,510AbandonedUS20030073181A1 (en)1998-07-022002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,504AbandonedUS20030049778A1 (en)1998-10-282002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,512AbandonedUS20030068746A1 (en)1998-11-032002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,936AbandonedUS20030049776A1 (en)2000-05-222002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,935AbandonedUS20030049775A1 (en)1998-06-032002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,506AbandonedUS20030207399A1 (en)1998-10-282002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,511AbandonedUS20030054481A1 (en)1998-06-242002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same

Family Applications After (94)

Application NumberTitlePriority DateFiling Date
US10/205,507AbandonedUS20030054480A1 (en)1998-05-222002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,939AbandonedUS20030049777A1 (en)2000-04-112002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/202,941AbandonedUS20030096358A1 (en)1998-09-292002-07-24Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,909AbandonedUS20030049783A1 (en)2000-03-032002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,891AbandonedUS20030073182A1 (en)2000-06-052002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,895AbandonedUS20030049780A1 (en)1999-03-232002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,897AbandonedUS20030059886A1 (en)2000-06-052002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,927AbandonedUS20030068764A1 (en)1999-08-032002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,911AbandonedUS20030068755A1 (en)2000-03-012002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/206,914AbandonedUS20030068758A1 (en)2000-03-012002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US10/205,904AbandonedUS20030073813A1 (en)1998-06-262002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
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US10/206,926AbandonedUS20030068763A1 (en)1999-07-202002-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
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US11/084,458AbandonedUS20050260632A1 (en)1998-06-242005-03-16Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/084,792AbandonedUS20060051777A1 (en)1998-04-212005-03-18Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/090,729AbandonedUS20060068413A1 (en)1998-09-182005-03-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/122,524AbandonedUS20060003355A1 (en)1998-08-172005-05-04Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/124,327AbandonedUS20050266461A1 (en)1997-11-212005-05-06Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/150,881AbandonedUS20060084084A1 (en)1998-07-022005-06-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/150,758AbandonedUS20060051784A1 (en)1998-07-022005-06-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/150,463AbandonedUS20060051783A1 (en)1998-08-262005-06-09Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/151,868AbandonedUS20060051785A1 (en)1998-06-182005-06-13Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/172,714AbandonedUS20060019287A1 (en)1998-06-052005-06-28Secreted and transmembrane polypeptides and nucleic acids encoding the same
US11/189,442AbandonedUS20060246465A1 (en)1998-06-042005-07-25Secreted and transmembrane polypeptides and nucleic acids encoding the same
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