TWI854034B

Movatterモバイル変換

Info

Publication number: TWI854034B
Application number: TW109133053A
Authority: TW
Inventors: 永田亮輔; 筒井生; 都合知一
Original assignee: 日商花王股份有限公司
Priority date: 2019-11-14
Filing date: 2020-09-24
Publication date: 2024-09-01
Also published as: WO2021095337A1; JP2021080172A; JP7379449B2; JP6901540B2; JP2023181425A; JP7591115B2; JP2021138733A; JP6985551B2; JP2022034566A; CN114585353A; TW202120059A

Abstract

Translated fromChinese

本發明之口腔內貼片(1)具備牙齒黏貼貼片(3)、及被覆該牙齒黏貼貼片(3)之要貼附於牙齒之面之剝離片(2)。牙齒黏貼貼片(3)具有沿著齒列之第1方向(X)及與該第1方向(X)正交之第2方向(Y)。牙齒黏貼貼片(3)具有本體部(30)、及自該本體部(30)向第1方向(X)之一側延出之延出部(36)。牙齒黏貼貼片(3)相對於將包含延出部(36)之第1方向(X)的總長度二等分之牙齒黏貼貼片中心線(CL1)左右不對稱地形成。The oral patch (1) of the present invention comprises a tooth adhesive patch (3) and a peeling sheet (2) covering the surface of the tooth adhesive patch (3) to be attached to the tooth. The tooth adhesive patch (3) has a first direction (X) along the tooth row and a second direction (Y) orthogonal to the first direction (X). The tooth adhesive patch (3) has a main body (30) and an extension (36) extending from the main body (30) to one side of the first direction (X). The tooth adhesive patch (3) is formed asymmetrically with respect to the center line (CL1) of the tooth adhesive patch that divides the total length of the first direction (X) including the extension (36) into two equal parts.

Description

Translated fromChinese

口腔內貼片Oral patch

本發明係關於一種貼附於牙齒使用之口腔內貼片。The present invention relates to an intraoral patch for use attached to teeth.

已知污漬沈積於牙齒之牙釉質表面或內部會導致牙齒著色，或者整個牙齒變色。基於增白牙齒及改善牙齒外觀的觀點，已揭示一種貼附於牙齒使用之貼片。例如專利文獻1中記載了一種牙齒美白貼片，其具備形狀互不相同之上齒用貼片及下齒用貼片，該等貼片具有特定寬度及形狀。It is known that stains deposited on the surface or inside of the enamel of teeth can cause tooth staining or discoloration of the entire tooth. Based on the viewpoint of whitening teeth and improving the appearance of teeth, a patch attached to teeth has been disclosed. For example, Patent Document 1 describes a tooth whitening patch, which has patches for upper teeth and patches for lower teeth of different shapes, and these patches have specific widths and shapes.

專利文獻2中記載了一種牙齒或牙床用貼附貼片，其於具有三層構造之支持體上形成有包含膏體組合物之黏著劑層，該三層構造包含2片水刺不織布、及介置於該等不織布間之特定厚度之聚乙烯或聚丙烯層。Patent document 2 describes a patch for teeth or gums, which has an adhesive layer containing a paste composition formed on a support having a three-layer structure, wherein the three-layer structure includes two spunlace non-woven fabrics and a polyethylene or polypropylene layer of a specific thickness interposed between the non-woven fabrics.

專利文獻3中記載一種用於遞送口腔護理活性物質之材料條，其具備具有對軸向伸長產生阻力之第1區域及第2區域之背襯層、以及配設於該背襯層上之口腔護理組合物，且該背襯層包含可應變之網狀組織，使用時產生至少2個階段之阻力。Patent document 3 describes a material strip for delivering oral care active substances, which has a backing layer having a first region and a second region that produce resistance to axial extension, and an oral care composition disposed on the backing layer, and the backing layer includes a strainable reticular tissue, which produces at least two stages of resistance when used.

先前技術文獻Prior art literature專利文獻Patent Literature

專利文獻1：美國專利申請公開第2006/193793號說明書Patent document 1: U.S. Patent Application Publication No. 2006/193793

專利文獻2：日本專利特開第2010-168370號公報Patent document 2: Japanese Patent Publication No. 2010-168370

專利文獻3：美國專利申請公開第2016/074290號說明書Patent document 3: U.S. Patent Application Publication No. 2016/074290

本發明係關於一種具備牙齒黏貼貼片、及被覆該牙齒黏貼貼片之要貼附於牙齒之面之剝離片的口腔內貼片。The present invention relates to an intraoral patch having a tooth adhesive patch and a peel-off patch covering the tooth adhesive patch and to be attached to the tooth surface.

上述牙齒黏貼貼片較佳為具有沿著齒列之第1方向及與該第1方向正交之第2方向，且具有本體部、及自該本體部向第1方向一側延出之延出部。The above-mentioned tooth adhesive patch preferably has a first direction along the tooth row and a second direction orthogonal to the first direction, and has a main body and an extension portion extending from the main body to one side of the first direction.

上述牙齒黏貼貼片較佳為相對於將包含上述延出部之第1方向的總長度二等分之牙齒黏貼貼片中心線左右不對稱地形成。The above-mentioned tooth adhesive patch is preferably formed asymmetrically with respect to the center line of the tooth adhesive patch which divides the total length of the first direction including the above-mentioned extension into two equal parts.

又，本發明係關於一種上述口腔內貼片之使用方法。Furthermore, the present invention relates to a method for using the above-mentioned oral patch.

上述使用方法較佳為，捏住上述延出部，自上述剝離片剝離上述牙齒黏貼貼片，於捏住上述延出部之狀態下，將上述牙齒黏貼貼片貼附於牙齒表面，將該牙齒黏貼貼片應用於該牙齒表面。The above-mentioned method of use is preferably to pinch the above-mentioned extension part, peel off the above-mentioned tooth adhesive patch from the above-mentioned peeling sheet, and adhere the above-mentioned tooth adhesive patch to the tooth surface while pinching the above-mentioned extension part, and apply the tooth adhesive patch to the tooth surface.

1:口腔內貼片1: Oral patch

2:剝離片2: Peel off the film

3:牙齒黏貼貼片3: Tooth adhesive patch

21:凸部21: convex part

30:本體部30: Headquarters

31:內縮部31: Inner part

32:凹部32: Concave part

36:延出部36: Extension

41:貼附面41: Attachment surface

42:作用層42: Action layer

43:凹部43: Concave part

44:保護層44: Protective layer

45:背面45: Back

A:上齒用貼片A: Patches for upper teeth

B:下齒用貼片B: Patches for lower teeth

CL1:牙齒黏貼貼片中心線CL1: Center line of tooth patch

CL2:本體部中心線CL2: Centerline of the body

F:第1區域F: Area 1

L:長度L: Length

L1:長度L1: Length

L2:長度L2: Length

R:第2區域R: Area 2

W:總寬度W: Total width

W1:寬度W1: Width

WL:回摺線WL: fold line

圖1係表示本發明之口腔內貼片之一實施方式之俯視圖。Figure 1 is a top view showing one implementation of the oral patch of the present invention.

圖2係圖1所示之牙齒黏貼貼片沿第1方向之剖視圖。Figure 2 is a cross-sectional view of the tooth adhesive patch shown in Figure 1 along the first direction.

圖3(a)~(c)係用以對圖1所示之口腔內貼片之使用方法進行說明之圖。Figures 3(a) to (c) are used to illustrate the use of the oral patch shown in Figure 1.

圖4(a)~(c)係表示本發明之牙齒黏貼貼片之另一實施方式之俯視圖。Figure 4 (a) to (c) are top views showing another embodiment of the tooth adhesive patch of the present invention.

專利文獻1~3之貼片在使用時貼附於牙齒表面來使用。然而，本發明者等人發現使用時口腔內貼片之操作性上存在以下課題：貼附操作中不知該貼片之牙齒黏貼面為哪一面，或者貼附操作中與牙齒黏貼面發生非必要接觸，導致對牙齒之應用效果下降。The patches of patent documents 1 to 3 are used by attaching them to the tooth surface. However, the inventors found that the operability of the patch in the oral cavity during use has the following problems: during the attaching operation, it is not known which side of the patch is attached to the tooth, or unnecessary contact occurs with the tooth cladding surface during the attaching operation, resulting in a decrease in the application effect on the tooth.

本發明係關於一種可解決先前技術中存在之上述解決課題之口腔內貼片。The present invention relates to an intraoral patch that can solve the above-mentioned problems existing in the prior art.

以下，基於本發明之較佳之實施方式，參照圖式對本發明進行說明。圖1及圖2中，示出本發明之口腔內貼片之一實施方式。本實施方式之口腔內貼片1具備牙齒黏貼貼片3、及被覆該牙齒黏貼貼片3之要貼附於牙齒之貼附面41之剝離片2。口腔內貼片1係藉由自剝離片2剝離牙齒黏貼貼片3，並將該牙齒黏貼貼片3貼附於牙齒來使用。下文將對使用方法詳細進行敍述。本實施方式之口腔內貼片1於使用前以牙齒黏貼貼片3之貼附面41與剝離片2對向之方式，可剝離地積層有該牙齒黏貼貼片3與剝離片2。口腔內貼片1亦可於剝離片2上可剝離地積層有面積與該剝離片2相同之牙齒黏貼貼片3，但較佳為於剝離片2上可剝離地積層有面積小於該剝離片2之牙齒黏貼貼片3。Hereinafter, the present invention will be described with reference to the drawings based on the preferred embodiment of the present invention. FIG. 1 and FIG. 2 show an embodiment of the oral patch of the present invention. The oral patch 1 of the present embodiment comprises a tooth adhesive patch 3 and a peeling sheet 2 covering the tooth adhesive patch 3 and an attachment surface 41 to be attached to the tooth. The oral patch 1 is used by peeling off the tooth adhesive patch 3 with the peeling sheet 2 and attaching the tooth adhesive patch 3 to the tooth. The method of use will be described in detail below. The oral patch 1 of this embodiment can be peeled off with the dental adhesive patch 3 and the peeling sheet 2 facing the attachment surface 41 of the dental adhesive patch 3 before use. The oral patch 1 can also be a dental adhesive patch 3 with a peelable surface layer on the peeling sheet 2 having the same area as the peeling sheet 2, but it is better to be a dental adhesive patch 3 with a peelable surface layer on the peeling sheet 2 having a smaller area than the peeling sheet 2.

牙齒黏貼貼片3具有貼附面41、及與該貼附面41相反側之面即背面45(參照圖2)。The tooth adhesive patch 3 has an adhesive surface 41 and a back surface 45 opposite to the adhesive surface 41 (see FIG. 2 ).

如圖2所示，本實施方式之牙齒黏貼貼片3具有積層構造，該積層構造積層有形成貼附面41之作用層42、及形成背面45之保護層44。As shown in FIG. 2 , the tooth adhesive patch 3 of the present embodiment has a laminated structure, and the laminated structure has an active layer 42 forming an attachment surface 41 and a protective layer 44 forming a back surface 45.

作用層42較佳為含有對牙齒或牙床、牙齦起作用之功能成分。功能成分於作用層42與牙齒或牙床、牙齦接觸之狀態下遷移至該牙齒或牙床、牙齦，展現該功能成分之作用。作用層42可含有能夠對選自由牙齒之牙釉質、牙本質、牙床、及牙齦所組成之群中之1個以上部位起作用之功能成分。功能成分無特別限制，地使用展現增白牙齒之作用、抑制冰冷食物刺痛之高度敏感之作用、預防齲齒或牙周疾病之作用等各種作用之成分。於本實施方式中，含有對牙齒起作用之功能成分，但亦可含有對牙床或牙齦起作用之功能成分。The action layer 42 preferably contains functional ingredients that act on teeth or gums, and gums. The functional ingredients migrate to the teeth or gums, and gums when the action layer 42 is in contact with the teeth or gums, and exhibit the effects of the functional ingredients. The action layer 42 may contain functional ingredients that can act on one or more parts selected from the group consisting of enamel, dentin, gums, and gums of teeth. The functional ingredients are not particularly limited, and ingredients that exhibit various effects such as whitening teeth, inhibiting high sensitivity to cold food stinging, and preventing tooth decay or periodontal disease are used. In this embodiment, functional ingredients that act on teeth are contained, but functional ingredients that act on gums or gums may also be contained.

於本實施方式中，作用層42對唾液具有溶解性。藉由該構成，能夠提高功能成分自作用層42向牙齒之遷移性。要想提高上述溶解性，較佳為於牙齒黏貼貼片3中作用層42，即形成貼附面41之部分含有水溶性高分子。In this embodiment, the active layer 42 is soluble in saliva. This structure can improve the migration of functional components from the active layer 42 to the teeth. In order to improve the above solubility, it is preferred that the active layer 42 in the tooth adhesive patch 3, that is, the part forming the attachment surface 41, contains a water-soluble polymer.

作為水溶性高分子，例如可列舉：聚乙烯吡咯啶酮、聚乙烯醇、聚乙烯醇縮丁醛、糊精、聚環氧乙烷、水溶性尼龍、天然多糖類等。作為天然多糖類，可列舉：海藻酸鈉、特蘭托膠、瓜爾膠、三仙膠、阿拉伯膠、角叉菜膠、半乳甘露聚糖、明膠、酪蛋白、白蛋白、支鏈澱粉等。Examples of water-soluble polymers include polyvinyl pyrrolidone, polyvinyl alcohol, polyvinyl butyral, dextrin, polyethylene oxide, water-soluble nylon, and natural polysaccharides. Examples of natural polysaccharides include sodium alginate, trantor gum, guar gum, santhemum gum, gum arabic, carrageenan, galactomannan, gelatin, casein, albumin, branched starch, and the like.

要想提高使用時牙齒黏貼貼片3之保型性，較佳為牙齒黏貼貼片3具有溶解性較作用層42低之保護層44。藉由該構成，能夠抑制於將牙齒黏貼貼片3貼附於牙齒或牙床、牙齦之狀態(以下，亦稱為貼附狀態)下，牙齒黏貼貼片3自背面45溶解。藉此，能夠提高功能成分向牙齒或牙床、牙齦之遷移性，並且減少因貼附狀態之牙齒黏貼貼片3發生溶解所帶來之不適。溶解性之高低係相對於唾液之溶解性，方便起見，亦可由對生理食鹽水之溶解性來判斷。In order to improve the shape retention of the dental adhesive patch 3 during use, it is preferred that the dental adhesive patch 3 has a protective layer 44 with a lower solubility than the active layer 42. With this structure, the dental adhesive patch 3 can be prevented from dissolving from the back 45 when the dental adhesive patch 3 is attached to the teeth or gums or gums (hereinafter also referred to as the attached state). In this way, the migration of functional components to the teeth or gums or gums can be improved, and the discomfort caused by the dissolution of the dental adhesive patch 3 in the attached state can be reduced. The solubility is relative to the solubility in saliva, and for convenience, it can also be judged by the solubility in physiological saline.

基於使如下所述般貼附於齒之牙齒黏貼貼片3脫離的觀點，較佳為保護層44含有具有親水基之水不溶性聚合物。該聚合物由於為水不溶性，故而呈疏水性，又，由於具有親水基，故而具有可分散於水或水溶性溶劑中之性質。作為上述聚合物，例如可列舉：乙基纖維素或羥基丙基纖維素等纖維素類、聚乙烯醇縮醛、玉米蛋白(玉米蛋白質之主要成分)、甘露聚醣、酪蛋白、尼龍、聚甲基丙烯酸樹脂等丙烯酸系樹脂、

唑啉改性矽酮等。該等聚合物可單獨使用1種或將2種以上組合使用。From the viewpoint of making the dental adhesive patch 3 attached to the tooth as described below detachable, it is preferred that the protective layer 44 contains a water-insoluble polymer having a hydrophilic group. Since the polymer is water-insoluble, it is hydrophobic, and since it has a hydrophilic group, it has a property of being dispersible in water or a water-soluble solvent. Examples of the above-mentioned polymer include celluloses such as ethyl cellulose and hydroxypropyl cellulose, polyvinyl alcohol acetal, zein (the main component of zein), mannan, casein, nylon, acrylic resins such as polymethacrylate resin,

Oxazoline-modified silicone, etc. These polymers may be used alone or in combination of two or more.

基於使用後容易使牙齒黏貼貼片3脫離牙齒表面的觀點，例如較佳為對作用層42使用支鏈澱粉，對保護層44使用乙基纖維素之組合。Based on the viewpoint that the tooth adhesive patch 3 is easy to be separated from the tooth surface after use, it is preferable to use a combination of branched starch for the active layer 42 and ethyl cellulose for the protective layer 44.

作用層42及保護層44各者除了含有上述成分以外，亦可含有其他各種添加劑。作為其他各種添加劑，例如可列舉：中和劑、塑化劑、界面活性劑、香料等。In addition to the above-mentioned components, each of the active layer 42 and the protective layer 44 may also contain various other additives. Examples of the various other additives include neutralizers, plasticizers, surfactants, fragrances, etc.

基於確保對牙齒等之優異之追隨性及密接性，並保持良好之貼附性之觀點，作用層42及保護層44之含水率較佳為5~16質量%，更佳為6~15質量%，進而較佳為7~14質量%。再者，含水率係指藉由使用利用卡氏法之水分計(例如，平沼產業股份有限公司、自動水分測定裝置AQV-300系列)之測定方法所獲得之值。In order to ensure excellent tracking and adhesion to teeth, etc., and maintain good adhesion, the moisture content of the active layer 42 and the protective layer 44 is preferably 5-16% by mass, more preferably 6-15% by mass, and further preferably 7-14% by mass. In addition, the moisture content refers to the value obtained by using a moisture meter using the Karl Fischer method (for example, Hiranuma Industry Co., Ltd., automatic moisture measuring device AQV-300 series).

剝離片2構成為可剝離牙齒黏貼貼片3。剝離片2之形成材料並無特別限制，例如可列舉：聚脂肪酸酯、聚碳酸酯、聚丙烯、聚乙烯、聚酯、聚醯胺、聚醯胺醯亞胺、聚醚醚酮、聚醚醯亞胺、聚苯乙烯、聚對苯二甲酸乙二酯、聚氯乙烯、尼龍樹脂、丙烯酸系樹脂等樹脂，可單獨使用其中1種或將2種以上組合使用。The peelable sheet 2 is constituted as a peelable tooth adhesive patch 3. The forming material of the peelable sheet 2 is not particularly limited, and examples thereof include: resins such as polyfatty acid ester, polycarbonate, polypropylene, polyethylene, polyester, polyamide, polyamide imide, polyetheretherketone, polyetherimide, polystyrene, polyethylene terephthalate, polyvinyl chloride, nylon resin, acrylic resin, etc., and one of them can be used alone or two or more can be used in combination.

本實施方式之口腔內貼片1具有貼附於上齒使用之上齒用貼片A、及貼附於下齒使用之下齒用貼片B作為牙齒黏貼貼片3。以下，只要未特殊說明，則牙齒黏貼貼片3之說明適用於上齒用貼片A及下齒用貼片B各者。The oral patch 1 of this embodiment has an upper tooth patch A attached to the upper teeth and a lower tooth patch B attached to the lower teeth as a tooth adhesive patch 3. Hereinafter, unless otherwise specified, the description of the tooth adhesive patch 3 applies to both the upper tooth patch A and the lower tooth patch B.

牙齒黏貼貼片3具有於貼附狀態下沿著齒列之第1方向X及與該第1方向X正交之第2方向Y。本實施方式之牙齒黏貼貼片3具有於第1方向X上較長之形狀。本實施方式之上齒用貼片A與下齒用貼片B亦可為第1方向X之長度互不相同。The tooth adhesive patch 3 has a first direction X along the tooth row in the attached state and a second direction Y orthogonal to the first direction X. The tooth adhesive patch 3 of this embodiment has a shape that is longer in the first direction X. The upper tooth patch A and the lower tooth patch B of this embodiment can also have different lengths in the first direction X.

牙齒黏貼貼片3具有本體部30、及自該本體部30向第1方向X一側延出之延出部36。本體部30係貼附於牙齒表面之主要部分。延出部36係第2方向Y之長度較本體部30短之部分。The tooth adhesive patch 3 has a main body 30 and an extension 36 extending from the main body 30 to one side in the first direction X. The main body 30 is the main part attached to the tooth surface. The extension 36 is a part shorter than the main body 30 in the second direction Y.

如本實施方式，上齒用貼片A與下齒用貼片B以將第1方向X上之本體部30的總長度二等分之本體部中心線CL2之位置相互一致之方式配置於同一剝離片2即可。上齒用貼片A與下齒用貼片B可以如本實施方式般可剝離地積層於同一剝離片2，亦可以可剝離地積層於連結在一起之剝離片，亦可以可剝離地積層於不同之剝離片。As in the present embodiment, the patch A for the upper teeth and the patch B for the lower teeth can be arranged on the same peeling sheet 2 in such a way that the positions of the center line CL2 of the main body portion that bisects the total length of the main body portion 30 in the first direction X are aligned with each other. The patch A for the upper teeth and the patch B for the lower teeth can be peelably layered on the same peeling sheet 2 as in the present embodiment, or can be peelably layered on peeling sheets connected together, or can be peelably layered on different peeling sheets.

於本實施方式中，牙齒黏貼貼片3具有貼附於齒正面側之第1區域F、及回折而貼附於齒背面側之第2區域R。本實施方式之牙齒黏貼貼片3當於齒正面側貼附有第1區域F之狀態下，以下述回摺線WL為交界回折第2區域R時，該第2區域R貼附於齒背面側。In this embodiment, the tooth adhesive patch 3 has a first region F attached to the front side of the tooth, and a second region R folded back and attached to the back side of the tooth. When the tooth adhesive patch 3 of this embodiment is attached to the front side of the tooth with the first region F attached, and the second region R is folded back with the following folding line WL as the boundary, the second region R is attached to the back side of the tooth.

本實施方式之本體部30相對於將第1方向X上之該本體部30的總長度二等分之本體部中心線CL2左右對稱地形成即可。如本實施方式，上齒用貼片A與下齒用貼片B亦可以如下方式配置於同一剝離片2，即，將包含延出部36之牙齒黏貼貼片3之第1方向X的總長度二等分之牙齒黏貼貼片中心線CL1之位置相互一致。The main body 30 of this embodiment can be formed symmetrically with respect to the main body center line CL2 that divides the total length of the main body 30 in the first direction X into two equal parts. As in this embodiment, the upper tooth patch A and the lower tooth patch B can also be arranged on the same peeling sheet 2 in the following manner, that is, the positions of the tooth adhesive patch center line CL1 that divides the total length of the tooth adhesive patch 3 including the extension portion 36 in the first direction X into two equal parts are consistent with each other.

牙齒黏貼貼片3相對於牙齒黏貼貼片中心線CL1左右不對稱地形成。具備該牙齒黏貼貼片3之口腔內貼片1於使用時操作性優異，可易於應用於牙齒表面。即，能夠抑制貼附操作中不知牙齒黏貼面為哪一面之情況，因此，能夠準確地應用於牙齒表面。參照圖3對該口腔內貼片1之操作性進行說明。The tooth adhesive patch 3 is formed asymmetrically with respect to the center line CL1 of the tooth adhesive patch. The oral patch 1 equipped with the tooth adhesive patch 3 has excellent operability during use and can be easily applied to the tooth surface. That is, it can suppress the situation of not knowing which side the tooth adhesive surface is during the pasting operation, so it can be accurately applied to the tooth surface. The operability of the oral patch 1 is explained with reference to Figure 3.

於口腔內貼片1之使用方法中，首先進行自剝離片2剝離牙齒黏貼貼片3之操作。牙齒黏貼貼片3如上所述左右不對稱地形成，因此，可易於辨別牙齒黏貼貼片3之左右及正反。又，使用者可直感地捏住延出部36，可易於自剝離片2剝離牙齒黏貼貼片3〔參照圖3(a)〕。而且，可於捏住延出部36之狀態下，直接將牙齒黏貼貼片3貼附於牙齒表面，可易於進行將該貼片3貼附於齒之操作〔參照圖3(b)〕。如此，藉由設置延出部36作為與使用者之手指等接觸之主要部位，剝離操作或貼附操作時，能夠儘量抑制本體部30之作用層42與使用者之手指等之接觸，從而穩定地維持本體部30之作用層42中之功能成分。即，能夠有效抑制本體部30之作用層42中功能成分之作用之降低。本發明者此次發現，尤其是於作用層42含有水溶性高分子之情形時，自剝離片2剝離牙齒黏貼貼片3時，有牙齒黏貼貼片3因手指之水分而溶解導致功能成分減少之虞。又，藉由具有延出部36，能夠抑制牙齒黏貼貼片3之貼附操作中不知貼附面為哪一面之情況，因此，能夠準確地應用於牙齒表面。In the method of using the intraoral patch 1, the operation of peeling off the tooth adhesive patch 3 from the peeling sheet 2 is first performed. The tooth adhesive patch 3 is formed asymmetrically as described above, so the left and right sides and the front and back of the tooth adhesive patch 3 can be easily distinguished. In addition, the user can intuitively pinch the extension 36, and can easily peel off the tooth adhesive patch 3 from the peeling sheet 2 (refer to Figure 3 (a)). Moreover, the tooth adhesive patch 3 can be directly attached to the tooth surface while pinching the extension 36, and the operation of attaching the patch 3 to the tooth can be easily performed (refer to Figure 3 (b)). Thus, by providing the extension portion 36 as the main part that contacts the user's fingers, etc., during the peeling operation or the sticking operation, the contact between the active layer 42 of the main body 30 and the user's fingers, etc. can be suppressed as much as possible, thereby stably maintaining the functional components in the active layer 42 of the main body 30. That is, the reduction of the function of the functional components in the active layer 42 of the main body 30 can be effectively suppressed. The inventors of the present invention have found that, especially when the active layer 42 contains a water-soluble polymer, when the tooth adhesive patch 3 is peeled off from the peeling sheet 2, there is a risk that the tooth adhesive patch 3 will dissolve due to the moisture of the fingers, resulting in a reduction in the functional components. Furthermore, by having the extension portion 36, it is possible to prevent the situation in which the tooth-adhesive patch 3 is not known which side is being attached during the attachment operation, so that it can be accurately applied to the tooth surface.

然後，將牙齒黏貼貼片3之第1區域F沿著齒列貼附於齒正面側。此時，延出部36亦貼附於牙齒表面。然後，將牙齒黏貼貼片3之第2區域R向齒背面側回折〔參照圖3(c)〕，將該第2區域R沿著齒列貼附於齒背面側，使牙齒黏貼貼片3成為貼附狀態。維持該貼附狀態特定時間之後，使用牙刷等連同牙齒黏貼貼片3進行刷洗，使牙齒黏貼貼片3崩解，之後用水漱口使牙齒黏貼貼片3脫離齒。Then, the first area F of the dental adhesive patch 3 is attached to the front side of the tooth along the tooth row. At this time, the extension 36 is also attached to the tooth surface. Then, the second area R of the dental adhesive patch 3 is folded back to the back side of the tooth [refer to Figure 3 (c)], and the second area R is attached to the back side of the tooth along the tooth row, so that the dental adhesive patch 3 becomes attached. After maintaining the attached state for a specific time, use a toothbrush or the like to brush together with the dental adhesive patch 3 to disintegrate the dental adhesive patch 3, and then rinse the mouth with water to remove the dental adhesive patch 3 from the tooth.

另一方面，相對於牙齒黏貼貼片中心線呈左右對稱而不具有延出部之先前之口腔內貼片中，自剝離片2剝離時，使用者應捏住何處並不明確。又，由於在剝離操作及貼附操作中，必須變更捏住牙齒黏貼貼片之部位，必須重新捏住牙齒黏貼貼片，因此操作容易變得繁雜。進而，存在因重新捏取而導致牙齒黏貼貼片彼此貼附，或該貼片貼附於使用者之手指之情況。有因貼附於該齒表面以外之處，而導致作用層42中之功能成分減少，功能成分之作用降低之虞。又，若牙齒黏貼貼片相對於其中心線左右對稱，則有貼附操作中不知貼附面為哪一面之情況。On the other hand, in the previous oral patch that is symmetrical with respect to the center line of the dental adhesive patch and does not have an extension, it is unclear where the user should pinch when peeling from the peeling sheet 2. In addition, since the part of the dental adhesive patch that is pinched must be changed during the peeling operation and the sticking operation, the dental adhesive patch must be pinched again, so the operation is easy to become complicated. Furthermore, there is a situation where the dental adhesive patch is attached to each other or the patch is attached to the user's finger due to re-pinching. There is a risk that the functional components in the active layer 42 are reduced and the function of the functional components is reduced due to sticking to a place other than the tooth surface. In addition, if the dental adhesive patch is symmetrical with respect to its center line, there is a situation where it is unknown which side is the sticking surface during the sticking operation.

基於針對自剝離片2剝離牙齒黏貼貼片3之操作及將牙齒黏貼貼片3貼附於齒之操作進一步提高操作性之觀點，牙齒黏貼貼片3之尺寸等較佳為以下範圍內。Based on the viewpoint of further improving the operability of the operation of peeling off the tooth adhesive patch 3 from the self-peeling sheet 2 and the operation of attaching the tooth adhesive patch 3 to the tooth, the size of the tooth adhesive patch 3 is preferably within the following range.

第1方向X上之延出部36之長度L1(參照圖1)相對於第1方向X上之牙齒黏貼貼片3的總長度L(參照圖1)，較佳為3%以上，更佳為10%以上，進而較佳為15%以上，且較佳為30%以下，更佳為25%以下，進而較佳為20%以下，且較佳為3%以上30%以下，更佳為10%以上25%以下，進而較佳為15%以上20%以下。The length L1 of the extension portion 36 in the first direction X (see FIG. 1) relative to the total length L of the tooth adhesive patch 3 in the first direction X (see FIG. 1) is preferably 3% or more, more preferably 10% or more, and further preferably 15% or more, and preferably 30% or less, more preferably 25% or less, and further preferably 20% or less, and preferably 3% or more and 30% or less, more preferably 10% or more and 25% or less, and further preferably 15% or more and 20% or less.

第1方向X上之延出部36之長度L1(參照圖1)較佳為2.8mm以上，更佳為5.6mm以上，進而較佳為8.4mm以上，且較佳為20.4mm以下，更佳為17mm以下，進而較佳為13.6mm以下，且較佳為2.8mm以上13.6mm以下，更佳為5.6mm以上17mm以下，進而較佳為8.4mm以上13.6mm以下。The length L1 of the extension portion 36 in the first direction X (see FIG. 1 ) is preferably 2.8 mm or more, more preferably 5.6 mm or more, and further preferably 8.4 mm or more, and preferably 20.4 mm or less, more preferably 17 mm or less, and further preferably 13.6 mm or less, and preferably 2.8 mm or more and 13.6 mm or less, more preferably 5.6 mm or more and 17 mm or less, and further preferably 8.4 mm or more and 13.6 mm or less.

第1方向X上之牙齒黏貼貼片3的總長度L(參照圖1)較佳為22mm以上，更佳為38mm以上，進而較佳為55mm以上，且較佳為112mm以下，更佳為91mm以下，進而較佳為70mm以下，且較佳為22mm以上112mm以下，更佳為38mm以上91mm以下，進而較佳為55mm以上70mm以下。The total length L of the tooth adhesive patch 3 in the first direction X (see FIG. 1 ) is preferably 22 mm or more, more preferably 38 mm or more, further preferably 55 mm or more, and preferably 112 mm or less, more preferably 91 mm or less, further preferably 70 mm or less, and preferably 22 mm or more and 112 mm or less, more preferably 38 mm or more and 91 mm or less, further preferably 55 mm or more and 70 mm or less.

延出部36之寬度W1(參照圖1)相對於牙齒黏貼貼片3的總寬度W(參照圖1)，較佳為20%以上，更佳為30%以上，進而較佳為40%以上，且較佳為70%以下，更佳為60%以下，進而較佳為50%以下，且較佳為20%以上70%以下，更佳為30%以上60%以下，進而較佳為40%以上50%以下。延出部36之寬度、及牙齒黏貼貼片3的總寬度W係其等之第2方向Y上之最大長度。The width W1 of the extension 36 (see FIG. 1) is preferably 20% or more, more preferably 30% or more, and more preferably 40% or more, and preferably 70% or less, more preferably 60% or less, and more preferably 50% or less, and preferably 20% or more and 70% or less, more preferably 30% or more and 60% or less, and more preferably 40% or more and 50% or less. The width of the extension 36 and the total width W of the tooth adhesive patch 3 are their maximum lengths in the second direction Y.

第1方向X上之牙齒黏貼貼片3的總長度L(參照圖1)相對於牙齒黏貼貼片3的總寬度W(參照圖1)，較佳為120%以上，更佳為190%以上，進而較佳為250%以上，且較佳為1000%以下，更佳為650%以下，進而較佳為310%以下，且較佳為120%以上1000%以下，更佳為190%以上650%以下，進而較佳為250%以上310%以下。The total length L of the tooth adhesive patch 3 in the first direction X (see FIG. 1) relative to the total width W of the tooth adhesive patch 3 (see FIG. 1) is preferably 120% or more, more preferably 190% or more, and further preferably 250% or more, and preferably 1000% or less, more preferably 650% or less, and further preferably 310% or less, and preferably 120% or more and 1000% or less, more preferably 190% or more and 650% or less, and further preferably 250% or more and 310% or less.

延出部36之寬度W1(參照圖1)較佳為4.4mm以上，更佳為6.6mm以上，進而較佳為8.8mm以上，且較佳為15.4mm以下，更佳為13.2mm以下，進而較佳為11mm以下，且較佳為4.4mm以上15.4mm以下，更佳為6.6mm以上13.2mm以下，進而較佳為8.8mm以上11mm以下。The width W1 of the extension portion 36 (see FIG. 1 ) is preferably 4.4 mm or more, more preferably 6.6 mm or more, and further preferably 8.8 mm or more, and preferably 15.4 mm or less, more preferably 13.2 mm or less, and further preferably 11 mm or less, and preferably 4.4 mm or more and 15.4 mm or less, more preferably 6.6 mm or more and 13.2 mm or less, and further preferably 8.8 mm or more and 11 mm or less.

牙齒黏貼貼片3的總寬度W(參照圖1)較佳為13mm以上，更佳為16mm以上，進而較佳為20mm以上，且較佳為35mm以下，更佳為32mm以下，進而較佳為29mm以下，且較佳為13mm以上35mm以下，更佳為16mm以上32mm以下，進而較佳為20mm以上29mm以下。The total width W (refer to FIG. 1 ) of the tooth adhesive patch 3 is preferably 13 mm or more, more preferably 16 mm or more, and further preferably 20 mm or more, and preferably 35 mm or less, more preferably 32 mm or less, and further preferably 29 mm or less, and preferably 13 mm or more and 35 mm or less, more preferably 16 mm or more and 32 mm or less, and further preferably 20 mm or more and 29 mm or less.

本實施方式之本體部30理想的是具有於第1方向X上較長之形狀。The main body 30 of this embodiment preferably has a shape that is longer in the first direction X.

第1方向X上之本體部30之長度L2(參照圖1)相對於第2方向Y上之牙齒黏貼貼片3的總寬度W，較佳為110%以上，更佳為150%以上，進而較佳為200%以上，且較佳為900%以下，更佳為600%以下，進而較佳為260%以下，且較佳為110%以上900%以下，更佳為150%以上600%以下，進而較佳為200%以上260%以下。The length L2 of the main body 30 in the first direction X (see FIG. 1 ) relative to the total width W of the tooth adhesive patch 3 in the second direction Y is preferably 110% or more, more preferably 150% or more, and further preferably 200% or more, and preferably 900% or less, more preferably 600% or less, and further preferably 260% or less, and preferably 110% or more and 900% or less, more preferably 150% or more and 600% or less, and further preferably 200% or more and 260% or less.

第1方向X上之本體部30之長度L2(參照圖1)較佳為20mm以上，更佳為30mm以上，進而較佳為40mm以上，且較佳為100mm以下，更佳為80mm以下，進而較佳為60mm以下，且較佳為20mm以上100mm以下，更佳為30mm以上80mm以下，進而較佳為40mm以上60mm以下。The length L2 of the main body 30 in the first direction X (see FIG. 1 ) is preferably 20 mm or more, more preferably 30 mm or more, and further preferably 40 mm or more, and preferably 100 mm or less, more preferably 80 mm or less, and further preferably 60 mm or less, and preferably 20 mm or more and 100 mm or less, more preferably 30 mm or more and 80 mm or less, and further preferably 40 mm or more and 60 mm or less.

基於進一步提高操作性及延出部36之視認性之觀點，較佳為延出部36偏向本體部30之第2方向Y一側配置。藉由該構成，可提高牙齒黏貼貼片3中之延出部36之視認性，並且於牙齒黏貼貼片3具有第1區域F及第2區域R之情形時，可易於進行貼附第1區域F之操作、及回折第2區域R之操作。From the perspective of further improving operability and visibility of the extension portion 36, it is preferred that the extension portion 36 is disposed toward the second direction Y side of the main body 30. This configuration can improve visibility of the extension portion 36 in the dental adhesive patch 3, and when the dental adhesive patch 3 has a first region F and a second region R, it is easy to attach the first region F and fold back the second region R.

延出部36可形成於第1區域F，或者亦可形成於第2區域R，基於更容易進行回折第2區域R之操作之觀點，較佳為形成於第1區域F，進而更佳為形成於第1區域F之第1方向X一端側。The extension 36 can be formed in the first region F or in the second region R. From the perspective of making it easier to fold back the second region R, it is preferably formed in the first region F, and more preferably formed on one end side of the first region F in the first direction X.

本實施方式之牙齒黏貼貼片3僅於本體部30之第1方向X一側具有延出部36，但牙齒黏貼貼片3亦可於本體部30之第1方向X兩側具有延出部36。由於將牙齒黏貼貼片3設為左右不對稱，故而於牙齒黏貼貼片3在本體部30之第1方向X兩側具有延出部36之情形時，此兩延出部較佳為其延出長度或形狀不同。即，較佳為於第1方向另一側，不具有與向第1方向一側延出之延出部36相比延出更大之延出部。但是，基於提高延出部36之視認性，以便於直感操作的觀點，更佳為牙齒黏貼貼片3不具有向第1方向X另一側延出之延出部36。The dental adhesive patch 3 of the present embodiment has the extension portion 36 only on one side of the main body 30 in the first direction X, but the dental adhesive patch 3 may also have the extension portion 36 on both sides of the main body 30 in the first direction X. Since the dental adhesive patch 3 is set to be asymmetrical, when the dental adhesive patch 3 has the extension portion 36 on both sides of the main body 30 in the first direction X, the two extension portions are preferably different in their extension length or shape. That is, it is preferred that there is no extension portion on the other side in the first direction that is larger than the extension portion 36 extending to one side in the first direction. However, from the perspective of improving the visibility of the extension portion 36 for intuitive operation, it is better that the tooth adhesive patch 3 does not have an extension portion 36 extending to the other side of the first direction X.

於圖1中之口腔內貼片1中，以如下狀態示出，即，以第1區域F位於上側、第2區域位於下側之方式配置上齒用貼片A，以第1區域F位於下側、第2區域位於上側之方式配置下齒用貼片B。該配置狀態與上齒用貼片A及下齒用貼片B於口腔內之配置關係對應，以便於直感操作，於此方面較佳。In the oral patch 1 in FIG. 1 , the following state is shown, that is, the upper tooth patch A is arranged in a manner that the first area F is located on the upper side and the second area is located on the lower side, and the lower tooth patch B is arranged in a manner that the first area F is located on the lower side and the second area is located on the upper side. This arrangement corresponds to the arrangement relationship of the upper tooth patch A and the lower tooth patch B in the oral cavity, so as to facilitate intuitive operation, which is better in this respect.

本實施方式之上齒用貼片A於上述配置狀態下自牙齒黏貼貼片3側正面觀察時，延出部36位於第1區域F之左側。於在本體部30之第1方向X兩側具有延出部36之情形時，較佳為此兩延出部36中第1方向X之長度較長者或面積較大者位於第1區域F之左側。When the upper tooth patch A of this embodiment is observed from the front side of the tooth-adhering patch 3 in the above configuration state, the extension 36 is located on the left side of the first area F. When there are extensions 36 on both sides of the main body 30 in the first direction X, it is preferred that the one with the longer length or larger area in the first direction X of the two extensions 36 is located on the left side of the first area F.

本實施方式之下齒用貼片B於上述配置狀態下自牙齒黏貼貼片3側正面觀察時，延出部36位於第1區域F之左側。於在本體部30之第1方向X兩側具有延出部36之情形時，較佳為此兩延出部36中第1方向X之長度較長者或面積較大者位於第1區域F之左側。In this embodiment, when the dental patch B is observed from the front side of the tooth-adhering patch 3 in the above configuration state, the extension 36 is located on the left side of the first area F. When there are extensions 36 on both sides of the main body 30 in the first direction X, it is preferred that the one with the longer length or larger area in the first direction X of the two extensions 36 is located on the left side of the first area F.

如此，基於右撇子使用者使用時之操作性之觀點，較佳為如下配置，即，延出部36位於左側之配置、或處於本體部30兩側之延出部36中第1方向X之長度較長者或面積較大者位於第1區域F之左側。具體而言，於右手捏住延出部36將牙齒黏貼貼片3剝離之情形時，可易於進行將貼附面41翻到近前側，將該貼附面41貼附於齒正面側之操作。Thus, from the perspective of operability when used by right-handed users, the following configuration is preferred, that is, the extension 36 is located on the left side, or the extension 36 on both sides of the main body 30 with a longer length in the first direction X or a larger area is located on the left side of the first area F. Specifically, when the right hand pinches the extension 36 to peel off the tooth adhesive patch 3, it is easy to turn the attachment surface 41 to the front side and attach the attachment surface 41 to the front side of the tooth.

於左撇子使用者使用之情形時，基於容易進行將貼附面41翻到手前側，將該貼附面41貼附於齒正面側之操作的觀點，較佳為上齒用貼片A及下齒用貼片B為以下配置。When used by a left-handed user, from the perspective of easily turning the attachment surface 41 to the front of the hand and attaching the attachment surface 41 to the front side of the teeth, it is preferred that the upper tooth patch A and the lower tooth patch B be configured as follows.

上齒用貼片A於上述配置狀態下自牙齒黏貼貼片3側正面觀察時，延出部36位於第1區域F之右側。於在本體部30之第1方向X兩側具有延出部36之情形時，此兩延出部36中第1方向X之長度較長者或面積較大者位於第1區域F之右側。When the upper tooth patch A is observed from the front side of the tooth-adhering patch 3 in the above configuration, the extension 36 is located on the right side of the first area F. When there are extensions 36 on both sides of the main body 30 in the first direction X, the one with a longer length or a larger area in the first direction X of the two extensions 36 is located on the right side of the first area F.

下齒用貼片B於上述配置狀態下自牙齒黏貼貼片3側正面觀察時，延出部36位於第1區域F之右側。於在本體部30之第1方向X兩側具有延出部36之情形時，此兩延出部36中第1方向X之長度較長者或面積較大者位於第1區域F之右側。When the lower tooth patch B is viewed from the front side of the tooth-adhering patch 3 in the above configuration, the extension 36 is located on the right side of the first area F. When there are extensions 36 on both sides of the main body 30 in the first direction X, the one with a longer length or a larger area in the first direction X is located on the right side of the first area F.

因此，基於進一步提高操作性的觀點，於上齒用貼片A與下齒用貼片B對齊第1方向，可剝離地積層於同一剝離片2或連結在一起之剝離片2之情形時，較佳為於上齒用貼片A與下齒用貼片B中，延出部36排列於第1方向X之相同側。換言之，較佳為於上齒用貼片A與下齒用貼片B中，延出部36向相同方向突出。或者於在本體部30之第1方向X兩側具有延出部36之情形時，較佳為於上齒用貼片A與下齒用貼片B中，向本體部30兩側突出之兩延出部36中第1方向X之長度較長者或面積較大者排列於第1方向X之相同側。Therefore, from the viewpoint of further improving operability, when the upper tooth patch A and the lower tooth patch B are aligned in the first direction and can be peeled off and layered on the same peeling sheet 2 or the peeling sheet 2 connected together, it is preferred that the extension 36 of the upper tooth patch A and the lower tooth patch B is arranged on the same side of the first direction X. In other words, it is preferred that the extension 36 of the upper tooth patch A and the lower tooth patch B protrude in the same direction. Or when there are extensions 36 on both sides of the main body 30 in the first direction X, it is preferred that the two extensions 36 protruding to both sides of the main body 30 in the upper tooth patch A and the lower tooth patch B are arranged on the same side of the first direction X with a longer length or a larger area.

本實施方式之牙齒黏貼貼片3如上所述具有第1區域F及第2區域R即可。本實施方式之牙齒黏貼貼片3為如下即可，即，於本體部30之第1方向X兩端部分別具有由朝向第1方向X之內側凹入之一對凹部所構成之內縮部31，且該內縮部31係將第2區域R回折之回折引導部。具體而言，當於齒正面側貼附有第1區域F之狀態下，以通過第2方向Y上之內縮部31中央之回摺線WL為交界回折第2區域R時，該第2區域R貼附於齒背面側。回摺線WL可為假想線，亦可由能引導回折之折頁線等形成。The tooth adhesive patch 3 of this embodiment has the first region F and the second region R as described above. The tooth adhesive patch 3 of this embodiment is as follows, that is, the two ends of the main body 30 in the first direction X respectively have a retracted portion 31 formed by a pair of concave portions that are concave inwardly toward the first direction X, and the retracted portion 31 is a folding guide portion for folding the second region R. Specifically, when the first region F is attached to the front side of the tooth, the second region R is folded back with the folding line WL passing through the center of the retracted portion 31 in the second direction Y as the boundary, and the second region R is attached to the back side of the tooth. The folding line WL can be an imaginary line, or it can be formed by a folding line that can guide the folding, etc.

於牙齒黏貼貼片3具有第1區域F及第2區域R之情形時，基於易於回折第2區域R的觀點，較佳為牙齒黏貼貼片3於本體部30之第1方向X兩端部具有將第2區域R沿第1方向X回折之回折引導部。於本實施方式中，回折引導部為上述內縮部31。構成該內縮部31之凹部可設為U字狀、半圓狀、三角形等多邊形狀等任意形狀。又，回折引導部可為分別形成於本體部30之第1方向X兩端部之一對切入部，亦可為形成於本體部30之第1方向X兩端部中任一端部之凹部或切入部。When the tooth adhesive patch 3 has the first area F and the second area R, based on the viewpoint of facilitating the folding of the second area R, it is preferred that the tooth adhesive patch 3 has a folding guide portion for folding the second area R along the first direction X at both ends of the main body 30 in the first direction X. In the present embodiment, the folding guide portion is the above-mentioned retracted portion 31. The recessed portion constituting the retracted portion 31 can be set to any shape such as a U-shape, a semicircle, a triangle or other polygonal shape. In addition, the folding guide portion can be a pair of cut-in portions formed at both ends of the main body 30 in the first direction X, or a recessed portion or a cut-in portion formed at any end of the two ends of the main body 30 in the first direction X.

進而，要想將第2區域R分割成複數個區域以提高回折之容易性，較佳為第2區域R具有1個或複數個將該第2區域R沿第1方向X分割成複數個區域之分割部。於本實施方式中，分割部為形成於第2區域R之第1方向X中央之1個凹部32即可。作為分割部之凹部32可設為U字狀、半圓狀、三角形等多邊形狀等任意形狀。又，分割部亦可為遍及第2區域R之第2方向Y總長度之切入部。分割部較佳為遍及第2區域R之第2方向Y總長度而形成。第2區域R之第2方向Y總長度係第2方向Y上之第2區域R之自第2方向Y外側側之端緣至回摺線WL之間。第2區域R可於第1方向X之任意位置具有1個或複數個分割部。於第2區域R具有1個分割部之情形時，基於與上述相同之觀點，較佳為分割部形成於本體部30之第2區域R之第1方向X中央。Furthermore, in order to divide the second region R into a plurality of regions to improve the ease of folding, it is preferred that the second region R has one or a plurality of dividing portions that divide the second region R into a plurality of regions along the first direction X. In the present embodiment, the dividing portion may be a recess 32 formed in the center of the second region R in the first direction X. The recess 32 serving as the dividing portion may be in any shape such as a U-shape, a semicircular shape, a triangle or other polygonal shape. Furthermore, the dividing portion may be a cut-in portion that extends over the total length of the second region R in the second direction Y. The dividing portion is preferably formed over the total length of the second region R in the second direction Y. The total length of the second region R in the second direction Y is from the end edge of the second region R on the outer side in the second direction Y to the folding line WL. The second region R may have one or more partitions at any position in the first direction X. When the second region R has one partition, based on the same viewpoint as above, it is preferred that the partition is formed at the center of the second region R of the main body 30 in the first direction X.

牙齒黏貼貼片3亦可為上齒用貼片A與下齒用貼片B各自之第1方向X上之長度互不相同。上齒由於較下齒更容易暴露於他人視線中，故而較佳為將美白等美化齒之範圍設定得較下齒大。基於該觀點，上齒用貼片A之第1方向X總長度相對於下齒用貼片B之第1方向X總長度，較佳為1.05倍以上，更佳為1.1倍以上，進而較佳為1.15倍以上，且較佳為10倍以下，更佳為5倍以下，進而較佳為1.25倍以下，且較佳為1.05倍以上10倍以下，更佳為1.1倍以上5倍以下，進而較佳為1.15倍以上1.25倍以下。上齒用貼片A及下齒用貼片B之各第1方向X總長度為各貼片A、B之第1方向X之最大長度。The tooth adhesive patch 3 may also be a patch A for upper teeth and a patch B for lower teeth, each having a different length in the first direction X. Since the upper teeth are more easily exposed to the eyes of others than the lower teeth, it is better to set the range of whitening and other beautification teeth to be larger than the lower teeth. Based on this viewpoint, the total length of the upper tooth patch A in the first direction X relative to the total length of the lower tooth patch B in the first direction X is preferably 1.05 times or more, more preferably 1.1 times or more, and further preferably 1.15 times or more, and preferably 10 times or less, more preferably 5 times or less, and further preferably 1.25 times or less, and preferably 1.05 times or more and 10 times or less, more preferably 1.1 times or more and 5 times or less, and further preferably 1.15 times or more and 1.25 times or less. The total length of each of the upper tooth patch A and the lower tooth patch B in the first direction X is the maximum length of each patch A and B in the first direction X.

本實施方式之牙齒黏貼貼片較佳為於其貼附於牙齒之面之表面具有凹部。該凹部例如可為與形成於剝離片2之凸部21對應之凹部43，將剝離片2剝離時，殘留於牙齒黏貼貼片3之貼附面41之表面者。藉此，對自剝離片2剝離後之牙齒黏貼貼片3，可利用上述凹部43辨別貼附面41與背面45。再者，剝離片2之凸部21亦可為藉由對剝離片2之表面實施之壓紋加工而得之凹凸。The tooth adhesive patch of the present embodiment preferably has a concave portion on the surface of the surface to be attached to the tooth. The concave portion may be, for example, a concave portion 43 corresponding to the convex portion 21 formed on the peeling sheet 2, which remains on the surface of the attachment surface 41 of the tooth adhesive patch 3 when the peeling sheet 2 is peeled off. Thus, the attachment surface 41 and the back surface 45 of the tooth adhesive patch 3 after the peeling sheet 2 is peeled off can be distinguished by the above-mentioned concave portion 43. Furthermore, the convex portion 21 of the peeling sheet 2 may also be a concave-convex obtained by embossing the surface of the peeling sheet 2.

要想進一步提高貼附面41與背面45之辨別性，形成於貼附面41之凹部43之深度較佳為8μm以上，更佳為11μm以上，進而較佳為15μm以上，且較佳為53μm以下，更佳為46μm以下，進而較佳為40μm以下，且較佳為8μm以上53μm以下，更佳為11μm以上46μm以下，進而較佳為15μm以上40μm以下。該凹部43之深度可藉由與下述<牙齒黏貼貼片3之厚度之測定方法>相同之方法測定。In order to further improve the distinguishability between the attachment surface 41 and the back surface 45, the depth of the concave portion 43 formed on the attachment surface 41 is preferably 8 μm or more, more preferably 11 μm or more, and further preferably 15 μm or more, and preferably 53 μm or less, more preferably 46 μm or less, and further preferably 40 μm or less, and preferably 8 μm or more and 53 μm or less, more preferably 11 μm or more and 46 μm or less, and further preferably 15 μm or more and 40 μm or less. The depth of the concave portion 43 can be measured by the same method as the <Method for measuring the thickness of the tooth adhesive patch 3> described below.

要想提高牙齒黏貼貼片3對齒表面或牙縫等凹凸之密接性，牙齒黏貼貼片3之厚度較佳為35μm以上，更佳為50μm以上，進而較佳為60μm以上，且較佳為500μm以下，更佳為150μm以下，進而較佳為70μm以下，且較佳為35μm以上500μm以下，更佳為50μm以上150μm以下，進而較佳為60μm以上70μm以下。牙齒黏貼貼片3之厚度可藉由以下方法測定。In order to improve the adhesion of the tooth adhesive patch 3 to the tooth surface or tooth gap, the thickness of the tooth adhesive patch 3 is preferably 35μm or more, more preferably 50μm or more, and more preferably 60μm or more, and preferably 500μm or less, more preferably 150μm or less, and more preferably 70μm or less, and preferably 35μm or more and 500μm or less, more preferably 50μm or more and 150μm or less, and more preferably 60μm or more and 70μm or less. The thickness of the tooth adhesive patch 3 can be measured by the following method.

<牙齒黏貼貼片3之厚度之測定方法><Method for measuring the thickness of tooth adhesive patch 3>

牙齒黏貼貼片3之厚度可使用數位顯微鏡(例如，KEYENCE製造之VHX-1000)測定。使用上述數位顯微鏡以20~100倍之倍率無負載地觀察牙齒黏貼貼片3之切割面，測定該切割面之最大厚度。測定係針對將牙齒黏貼貼片3於任意3處切割而得之各截面進行，將此3處之最大厚度之平均值作為牙齒黏貼貼片3之厚度。The thickness of the dental adhesive patch 3 can be measured using a digital microscope (e.g., VHX-1000 manufactured by KEYENCE). The above digital microscope is used to observe the cut surface of the dental adhesive patch 3 without load at a magnification of 20 to 100 times, and the maximum thickness of the cut surface is measured. The measurement is performed on each cross section obtained by cutting the dental adhesive patch 3 at any three locations, and the average value of the maximum thickness of these three locations is taken as the thickness of the dental adhesive patch 3.

基於提高將牙齒黏貼貼片3貼附於齒之操作性的觀點，牙齒黏貼貼片3之拉伸強度為20MPa時之應變較佳為2%以上，更佳為3%以上，進而較佳為4%以上，進而更佳為5%以上。再者，牙齒黏貼貼片3之拉伸強度為20MPa時之應變可藉由以下方法測定。From the perspective of improving the operability of attaching the dental adhesive patch 3 to the tooth, the strain when the tensile strength of the dental adhesive patch 3 is 20MPa is preferably 2% or more, more preferably 3% or more, further preferably 4% or more, and further preferably 5% or more. Furthermore, the strain when the tensile strength of the dental adhesive patch 3 is 20MPa can be measured by the following method.

<應變之測定方法><Method for measuring strain>

利用流變儀(AntonPaar製造、MCR502)進行針對拉伸強度20MPa之牙齒黏貼貼片之應變之測定。將測定對象貼片放置於用以測定應變之治具，測定應變。解析軟體使用Rheoplus32。測定治具使用通用伸長測定系統(UXF12/UNI)。測量於室溫環境下(約25℃)下使拉伸應力於1~20MPa內變化時之拉伸應變。測定時間設為30秒，以1點/1秒線性控制拉伸應力。拉伸應變由%表示夾在旋轉筒與固定筒之貼片的初始長度約20mm起之變化量。The strain of a tooth adhesive patch with a tensile strength of 20 MPa was measured using a rheometer (manufactured by Anton Paar, MCR502). The patch to be measured was placed on a jig for measuring strain and the strain was measured. The analysis software used was Rheoplus32. The measurement jig used a universal elongation measurement system (UXF12/UNI). The tensile strain was measured when the tensile stress varied within 1~20 MPa at room temperature (about 25°C). The measurement time was set to 30 seconds, and the tensile stress was linearly controlled at 1 point/1 second. The tensile strain is expressed in % as the change in the initial length of the patch between the rotating cylinder and the fixed cylinder from about 20 mm.

基於容易根據齒面之凹凸或齒之排列來貼附牙齒黏貼貼片3的觀點，牙齒黏貼貼片3之霧值(濁度)較佳為80以下，更佳為70以下，進而較佳為60以下，進而更佳為50以下。霧值由以下方法測定。From the viewpoint of being easy to attach the dental adhesive patch 3 according to the unevenness of the tooth surface or the arrangement of the teeth, the haze value (turbidity) of the dental adhesive patch 3 is preferably 80 or less, more preferably 70 or less, further preferably 60 or less, and further preferably 50 or less. The haze value is measured by the following method.

<霧值(濁度)之測定方法><Measurement method of fog value (turbidity)>

按照日本工業標準之塑膠製品試驗方法(JIS K 7136)測定霧值(濁度)。霧值係使用測霧計(日本電色工業股份有限公司製造、商品名「NDH7000II」)測定。根據樣品上之任意3點之測定結果，將其平均值作為霧值。The mist value (turbidity) is measured according to the Japanese Industrial Standards for Testing Plastic Products (JIS K 7136). The mist value is measured using a mist meter (manufactured by Nippon Denshoku Industries Co., Ltd., trade name "NDH7000II"). The average value of the measurement results at any three points on the sample is taken as the mist value.

基於更容易進行自剝離片2剝離牙齒黏貼貼片3之操作的觀點，較佳為牙齒黏貼貼片3與剝離片2之顏色互不相同。From the perspective of making it easier to peel off the tooth adhesive patch 3 by the peeling sheet 2, it is preferred that the tooth adhesive patch 3 and the peeling sheet 2 have different colors.

如上所述，牙齒黏貼貼片3含有水溶性高分子而構成。基於抑制使用前牙齒黏貼貼片3吸濕的觀點，較佳為口腔內貼片1由包裝材獨立包裝。基於與上述相同之觀點，較佳為包裝材將其內部密閉。該包裝材藉由使用超音波密封、熱密封、高頻密封等公知之接合方法將1片或複數片貼片接合而形成。作為包裝材之形成材料，例如可列舉：熱塑性樹脂膜、於該膜層壓有鋁等之金屬薄膜者等。As described above, the dental adhesive patch 3 is composed of a water-soluble polymer. From the perspective of suppressing moisture absorption of the front dental adhesive patch 3 during use, it is preferred that the oral patch 1 is independently packaged by a packaging material. From the same perspective as above, it is preferred that the packaging material seals the inside. The packaging material is formed by joining one or more patches using a known joining method such as ultrasonic sealing, heat sealing, and high-frequency sealing. As the forming material of the packaging material, for example, there can be listed: a thermoplastic resin film, a metal film such as aluminum pressed on the film layer, etc.

以上，對本發明之較佳之實施方式進行了說明，但本發明並不限制於上述實施方式，可於不脫離本發明主旨之範圍內進行各種變更。The above describes the preferred implementation of the present invention, but the present invention is not limited to the above implementation, and various changes can be made within the scope of the present invention.

例如，上述實施方式之口腔內貼片1之牙齒黏貼貼片3具有積層有作用層42與保護層44之積層構造，但牙齒黏貼貼片3可僅由作用層42構成，亦可於作用層42與保護層44之間進一步具有中間層。For example, the dental adhesive patch 3 of the oral patch 1 of the above-mentioned embodiment has a layered structure including an active layer 42 and a protective layer 44, but the dental adhesive patch 3 may be composed of only the active layer 42, or may further have an intermediate layer between the active layer 42 and the protective layer 44.

又，上述實施方式之本體部30具有於第1方向X上較長之形狀，但亦可不具有於一方向較長之形狀。例如本體部30可為第2方向Y之長度係相當於齒之高度方向之長度，或者較其短之長度。又，本體部30亦可為大致正方形〔參照圖4(a)〕。In addition, the main body 30 of the above-mentioned embodiment has a shape that is longer in the first direction X, but it may not have a shape that is longer in one direction. For example, the length of the main body 30 in the second direction Y may be equal to the length in the height direction of the tooth, or shorter than the length. In addition, the main body 30 may also be a roughly square shape [refer to Figure 4(a)].

又，上述實施方式之牙齒黏貼貼片3具有第1區域F及第2區域R，但牙齒黏貼貼片3亦可僅具有第1區域F或第2區域R。例如，牙齒黏貼貼片3亦可為如下形態，即，具有由相當於第1區域F之部分所構成之本體部30，且於該本體部30之第1方向X一側具有偏向該本體部30之第2方向Y上之中央或一側配置的延出部36〔參照圖4(b)及(c)〕。Furthermore, the dental adhesive patch 3 of the above-mentioned embodiment has the first region F and the second region R, but the dental adhesive patch 3 may also have only the first region F or the second region R. For example, the dental adhesive patch 3 may also be in the following form, that is, having a main body 30 composed of a portion corresponding to the first region F, and having an extension portion 36 disposed toward the center or one side of the main body 30 in the second direction Y on one side of the main body 30 in the first direction X (see Figures 4 (b) and (c)).

又，上述實施方式之口腔內貼片1具有上齒用貼片A及下齒用貼片B，但口腔內貼片1亦可僅具有上齒用貼片A或下齒用貼片B。Furthermore, the oral patch 1 of the above-mentioned embodiment has a patch A for upper teeth and a patch B for lower teeth, but the oral patch 1 may also have only a patch A for upper teeth or a patch B for lower teeth.

<1><1>

一種口腔內貼片，其係具備牙齒黏貼貼片、及被覆該牙齒黏貼貼片之要貼附於牙齒之面之剝離片者，且上述牙齒黏貼貼片具有沿著齒列之第1方向及與該第1方向正交之第2方向，且具有本體部、及自該本體部向第1方向一側延出之延出部，上述牙齒黏貼貼片相對於將包含上述延出部之第1方向的總長度二等分之牙齒黏貼貼片中心線左右不對稱地形成。An intraoral patch, comprising a tooth adhesive patch and a peel-off sheet covering the tooth adhesive patch to be attached to the tooth, wherein the tooth adhesive patch has a first direction along the tooth row and a second direction orthogonal to the first direction, and has a main body and an extension extending from the main body to one side of the first direction, and the tooth adhesive patch is formed asymmetrically with respect to the center line of the tooth adhesive patch that divides the total length of the first direction including the extension into two equal parts.

<2><2>

如上述<1>中記載之口腔內貼片，其中上述牙齒黏貼貼片具有第2方向之長度互不相同之上述本體部及上述延出部，該延出部自該本體部之第1方向一端延出。As described in <1> above, the dental adhesive patch has the main body and the extension, which have different lengths in the second direction, and the extension extends from one end of the main body in the first direction.

<3><3>

如上述<1>或<2>中記載之口腔內貼片，其中上述牙齒黏貼貼片具有於第1方向上較長之形狀。An intraoral patch as described in <1> or <2> above, wherein the tooth adhesive patch has a shape that is longer in the first direction.

<4><4>

如上述<3>中記載之口腔內貼片，其中第1方向上之上述牙齒黏貼貼片的總長度L相對於該牙齒黏貼貼片的總寬度W為120%以上，較佳為190%以上，更佳為250%以上，且為1000%以下，較佳為650%以下，更佳為310%以下，且為120%以上1000%以下，較佳為190%以上650%以下，更佳為250%以上310%以下。As described in <3> above, the total length L of the above-mentioned tooth adhesive patch in the first direction is 120% or more, preferably 190% or more, more preferably 250% or more, and 1000% or less, preferably 650% or less, more preferably 310% or less, and 120% or more and 1000% or less, preferably 190% or more and 650% or less, more preferably 250% or more and 310% or less.

<5><5>

如上述<1>至<4>中任一項記載之口腔內貼片，其中第1方向上之上述延出部之長度L1相對於第1方向上之上述牙齒黏貼貼片的總長度L為3%以上，較佳為10%以上，更佳為15%以上，且為30%以下，較佳為25%以下，更佳為20%以下，且為3%以上30%以下，較佳為10%以上25%以下，更佳為15%以上20%以下。For an oral patch as described in any one of <1> to <4> above, the length L1 of the extension portion in the first direction is 3% or more, preferably 10% or more, more preferably 15% or more, and 30% or less, preferably 25% or less, more preferably 20% or less, and 3% or more and 30% or less, preferably 10% or more and 25% or less, more preferably 15% or more and 20% or less relative to the total length L of the tooth adhesive patch in the first direction.

<6><6>

如上述<5>中記載之口腔內貼片，其中第1方向上之上述延出部之長度L1為2.8mm以上，較佳為5.6mm以上，更佳為8.4mm以上，且為20.4mm以下，較佳為17mm以下，更佳為13.6mm以下，且為2.8mm以上13.6mm以下，較佳為5.6mm以上17mm以下，更佳為8.4mm以上13.6mm以下。For the oral patch described in <5> above, the length L1 of the extension portion in the first direction is 2.8 mm or more, preferably 5.6 mm or more, more preferably 8.4 mm or more, and 20.4 mm or less, preferably 17 mm or less, more preferably 13.6 mm or less, and 2.8 mm or more and 13.6 mm or less, preferably 5.6 mm or more and 17 mm or less, more preferably 8.4 mm or more and 13.6 mm or less.

<7><7>

如上述<5>或<6>中記載之口腔內貼片，其中第1方向上之上述牙齒黏貼貼片的總長度L為22mm以上，較佳為38mm以上，更佳為55mm以上，且為112mm以下，較佳為91mm以下，更佳為70mm以下，且為22mm以上112mm以下，較佳為38mm以上91mm以下，更佳為55mm以上70mm以下。For the oral patch described in <5> or <6> above, the total length L of the tooth-adhesive patch in the first direction is 22 mm or more, preferably 38 mm or more, more preferably 55 mm or more, and 112 mm or less, preferably 91 mm or less, more preferably 70 mm or less, and 22 mm or more and 112 mm or less, preferably 38 mm or more and 91 mm or less, more preferably 55 mm or more and 70 mm or less.

<8><8>

如上述<1>至<7>中任一項記載之口腔內貼片，其中上述本體部相對於將包含上述第1方向上之該本體部的總長度二等分之本體部中心線左右對稱地形成。An intraoral patch as described in any one of <1> to <7> above, wherein the main body is formed symmetrically with respect to a center line of the main body that divides the total length of the main body in the first direction into two equal parts.

<9><9>

如上述<1>至<8>中任一項記載之口腔內貼片，其中上述本體部具有於第1方向上較長之形狀。An oral patch as described in any one of <1> to <8> above, wherein the main body has a shape that is longer in the first direction.

<10><10>

如上述<9>中記載之口腔內貼片，其中第1方向上之上述本體部之長度L2相對於第2方向上之上述牙齒黏貼貼片的總寬度W為110%以上，較佳為150%以上，更佳為200%以上，且為900%以下，較佳為600%以下，更佳為260%以下，且為110%以上900%以下，較佳為150%以上600%以下，更佳為200%以上260%以下。For the oral patch described in <9>, the length L2 of the main body in the first direction is 110% or more, preferably 150% or more, more preferably 200% or more, and 900% or less, preferably 600% or less, more preferably 260% or less, and 110% or more and 900% or less, preferably 150% or more and 600% or less, more preferably 200% or more and 260% or less relative to the total width W of the tooth adhesive patch in the second direction.

<11><11>

如上述<9>或<10>中記載之口腔內貼片，其中第1方向上之上述本體部之長度L2為20mm以上，較佳為30mm以上，更佳為40mm以上，且為100mm以下，較佳為80mm以下，更佳為60mm以下，且為20mm以上100mm以下，較佳為30mm以上80mm以下，更佳為40mm以上60mm以下。For the oral patch described in <9> or <10>, the length L2 of the main body in the first direction is 20 mm or more, preferably 30 mm or more, more preferably 40 mm or more, and 100 mm or less, preferably 80 mm or less, more preferably 60 mm or less, and 20 mm or more and 100 mm or less, preferably 30 mm or more and 80 mm or less, more preferably 40 mm or more and 60 mm or less.

<12><12>

如上述<1>至<11>中任一項記載之口腔內貼片，其中上述延出部偏向上述本體部之第2方向一側配置。An oral patch as described in any one of <1> to <11> above, wherein the extension portion is disposed toward one side of the second direction of the main body portion.

<13><13>

如上述<12>中記載之口腔內貼片，其中上述延出部之寬度W1相對於上述牙齒黏貼貼片的總寬度W為20%以上，較佳為30%以上，更佳為40%以上，且為70%以下，較佳為60%以下，更佳為50%以下，且為20%以上70%以下，較佳為30%以上60%以下，更佳為40%以上50%以下。As described in <12> above, the width W1 of the extension portion is 20% or more, preferably 30% or more, more preferably 40% or more, and 70% or less, preferably 60% or less, more preferably 50% or less, and 20% or more and 70% or less, preferably 30% or more and 60% or less, more preferably 40% or more and 50% or more.

<14><14>

如上述<13>中記載之口腔內貼片，其中上述延出部之寬度W1為4.4mm以上，較佳為6.6mm以上，更佳為8.8mm以上，且為15.4mm以下，較佳為13.2mm以下，更佳為11mm以下，且為4.4mm以上15.4mm以下，較佳為6.6mm以上13.2mm以下，更佳為8.8mm以上11mm以下。As described in <13> above, the width W1 of the extension portion is 4.4 mm or more, preferably 6.6 mm or more, more preferably 8.8 mm or more, and 15.4 mm or less, preferably 13.2 mm or less, more preferably 11 mm or less, and 4.4 mm or more and 15.4 mm or less, preferably 6.6 mm or more and 13.2 mm or less, more preferably 8.8 mm or more and 11 mm or less.

<15><15>

如上述<13>或<14>中記載之口腔內貼片，其中上述牙齒黏貼貼片的總寬度W為13mm以上，較佳為16mm以上，更佳為20mm以上，且為35mm以下，較佳為32mm以下，更佳為29mm以下，且為13mm以上35mm以下，較佳為16mm以上32mm以下，更佳為20mm以上29mm以下。As described in <13> or <14> above, the total width W of the above-mentioned tooth adhesive patch is 13 mm or more, preferably 16 mm or more, more preferably 20 mm or more, and 35 mm or less, preferably 32 mm or less, more preferably 29 mm or less, and 13 mm or more and 35 mm or less, preferably 16 mm or more and 32 mm or less, more preferably 20 mm or more and 29 mm or less.

<16><16>

如上述<1>至<15>中任一項記載之口腔內貼片，其於上述本體部之第1方向兩側具有上述延出部。The oral patch described in any one of <1> to <15> above has the above-mentioned extension part on both sides of the above-mentioned main body in the first direction.

<17><17>

如上述<1>至<15>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片不具有向第1方向另一側延出之延出部。An intraoral patch as described in any one of <1> to <15> above, wherein the tooth adhesive patch does not have an extension portion extending to the other side of the first direction.

<18><18>

如上述<1>至<17>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片具有貼附於齒正面側之第1區域、及回折而貼附於齒背面側之第2區域，且上述延出部形成於第1區域。An intraoral patch as described in any one of <1> to <17> above, wherein the tooth adhesive patch has a first region attached to the front side of the tooth and a second region folded back and attached to the back side of the tooth, and the extension is formed in the first region.

<19><19>

如上述<18>中記載之口腔內貼片，其中上述牙齒黏貼貼片具有將第2區域回折之回折引導部，且該回折引導部由形成於本體部之第1方向兩端部中任一端部之凹部或切入部構成。As described in <18> above, the dental adhesive patch has a folding guide portion for folding back the second area, and the folding guide portion is composed of a recessed portion or a cut-in portion formed at either end of the first direction of the main body.

<20><20>

如上述<19>中記載之口腔內貼片，其中上述牙齒黏貼貼片於上述本體部之第1方向兩端部分別具有由朝向該第1方向之內側凹入之一對凹部所構成之內縮部作為上述回折引導部，構成該內縮部之凹部具有U字狀、半圓狀、或多邊形狀。As described in <19> above, the dental adhesive patch has a retracted portion formed by a pair of concave portions that are concave inwardly toward the first direction at both ends of the main body as the folding guide portion, and the concave portion forming the retracted portion has a U-shape, a semicircular shape, or a polygonal shape.

<21><21>

如上述<18>至<20>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片具有1個或複數個將第2區域沿第1方向分割成複數個區域之分割部。An oral patch as described in any one of <18> to <20> above, wherein the tooth adhesive patch has one or more dividing parts that divide the second area into a plurality of areas along the first direction.

<22><22>

如上述<21>中記載之口腔內貼片，其中上述分割部係遍及第2區域之第2方向總長度之切入部。As described in the above-mentioned <21>, the above-mentioned dividing portion is a cutting portion covering the total length of the second direction of the second area.

<23><23>

如上述<21>或<22>中記載之口腔內貼片，其中上述分割部形成於第2區域之第1方向中央。As described in <21> or <22> above, the above-mentioned dividing portion is formed in the center of the second area in the first direction.

<24><24>

如上述<21>中記載之口腔內貼片，其中上述分割部係形成於第2區域之第1方向中央之1個凹部，其形狀為U字狀、半圓狀、或多邊形狀。As described in the above-mentioned <21>, the above-mentioned dividing portion is a concave portion formed in the center of the second area in the first direction, and its shape is U-shaped, semicircular, or polygonal.

<25><25>

如上述<18>至<24>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片係貼附於上齒使用之上齒用貼片，且以第1區域位於上側、第2區域位於下側之方式配置上述牙齒黏貼貼片，自該牙齒黏貼貼片側正面觀察時，上述延出部位於第1區域之左側。An intraoral patch as described in any one of <18> to <24> above, wherein the dental adhesive patch is an upper tooth patch that is attached to the upper teeth, and the dental adhesive patch is arranged in such a manner that the first area is located on the upper side and the second area is located on the lower side, and when the dental adhesive patch is observed from the front side, the extension portion is on the left side of the first area.

<26><26>

如上述<18>至<24>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片係貼附於下齒使用之下齒用貼片，且以第1區域位於下側、第2區域位於上側之方式配置上述牙齒黏貼貼片，自該牙齒黏貼貼片側正面觀察時，上述延出部位於第1區域之左側。An intraoral patch as described in any one of <18> to <24> above, wherein the dental adhesive patch is a lower tooth patch attached to the lower teeth, and the dental adhesive patch is arranged in such a manner that the first area is located at the lower side and the second area is located at the upper side, and when the dental adhesive patch is observed from the front side, the extension portion is on the left side of the first area.

<27><27>

如上述<1>至<26>中任一項記載之口腔內貼片，其中作為上述牙齒黏貼貼片，貼附於上齒使用之上齒用貼片與貼附於下齒使用之下齒用貼片對齊第1方向，貼附於同一剝離片或連結在一起之剝離片，且於上述上齒用貼片及上述下齒用貼片中，上述延出部排列於第1方向之相同側。As described in any one of <1> to <26> above, the oral patch as the above-mentioned tooth adhesive patch, the upper tooth patch attached to the upper teeth and the lower tooth patch attached to the lower teeth are aligned in the first direction, attached to the same peel-off sheet or peel-off sheets connected together, and in the above-mentioned upper tooth patch and the above-mentioned lower tooth patch, the above-mentioned extension portion is arranged on the same side in the first direction.

<28><28>

如上述<27>中記載之口腔內貼片，其中上述牙齒黏貼貼片係上述上齒用貼片與上述下齒用貼片各自之第1方向上之長度互不相同。As described in the above-mentioned <27>, the above-mentioned tooth adhesive patch is that the lengths of the above-mentioned upper tooth patch and the above-mentioned lower tooth patch in the first direction are different from each other.

<29><29>

如上述<28>中記載之口腔內貼片，其中上述上齒用貼片之第1方向總長度相對於上述下齒用貼片之第1方向總長度為1.05倍以上，較佳為1.1倍以上，更佳為1.15倍以上，且為10倍以下，較佳為5倍以下，更佳為1.25倍以下，且為1.05倍以上10倍以下，較佳為1.1倍以上5倍以下，更佳為1.15倍以上1.25倍以下。As described in the above-mentioned <28>, the total length of the upper tooth patch in the first direction is 1.05 times or more, preferably 1.1 times or more, more preferably 1.15 times or more, and is less than 10 times, preferably less than 5 times, more preferably less than 1.25 times, and is more than 1.05 times and less than 10 times, preferably more than 1.1 times and less than 5 times, and more preferably more than 1.15 times and less than 1.25 times.

<30><30>

如上述<1>至<29>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片具備作用層，該作用層形成要貼附於牙齒之面，且含有對牙齒起作用之功能成分。An oral patch as described in any one of <1> to <29> above, wherein the tooth adhesive patch has an active layer, the active layer forms a surface to be attached to the teeth and contains functional ingredients that act on the teeth.

<31><31>

如上述<30>中記載之口腔內貼片，其中上述作用層對唾液具有溶解性。As described in <30> above, the oral patch, wherein the active layer is soluble in saliva.

<32><32>

如上述<31>中記載之口腔內貼片，其中上述作用層具有水溶性高分子。As described in <31> above, the oral patch, wherein the above-mentioned active layer has a water-soluble polymer.

<33><33>

如上述<32>中記載之口腔內貼片，其中上述水溶性高分子係選自聚乙烯吡咯啶酮、聚乙烯醇、聚乙烯醇縮丁醛、糊精、聚環氧乙烷、水溶性尼龍、及天然多糖類中之1種或2種以上。As described in <32> above, the water-soluble polymer is selected from one or more of polyvinyl pyrrolidone, polyvinyl alcohol, polyvinyl butyral, dextrin, polyethylene oxide, water-soluble nylon, and natural polysaccharides.

<34><34>

如上述<33>中記載之口腔內貼片，其中上述天然多糖類係選自海藻酸鈉、特蘭托膠、瓜爾膠、三仙膠、阿拉伯膠、角叉菜膠、半乳甘露聚糖、明膠、酪蛋白、白蛋白、及支鏈澱粉中之1種或2種以上。As described in the oral patch in <33> above, the natural polysaccharide is selected from one or more of sodium alginate, terental gum, guar gum, tannic gum, gum arabic, carrageenan, galactomannan, gelatin, casein, albumin, and branched starch.

<35><35>

如上述<30>至<34>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片具有積層有上述作用層、及溶解性較該作用層低之保護層之積層構造。An oral patch as described in any one of <30> to <34> above, wherein the dental adhesive patch has a layered structure including the above-mentioned active layer and a protective layer having a lower solubility than the active layer.

<36><36>

如上述<35>中記載之口腔內貼片，其中上述保護層含有具有親水基之水不溶性聚合物。As described in <35> above, the protective layer contains a water-insoluble polymer having a hydrophilic group.

<37><37>

如上述<36>中記載之口腔內貼片，其中上述聚合物係選自纖維素類、聚乙烯醇縮醛、玉米蛋白(玉米蛋白質之主要成分)、甘露聚醣、酪蛋白、尼龍、丙烯酸系樹脂、及

唑啉改性矽酮中之1種或2種以上，且上述纖維素類包含乙基纖維素及羥基丙基纖維素之一種或兩種，上述丙烯酸系樹脂包含聚甲基丙烯酸樹脂。The oral patch as described in <36>, wherein the polymer is selected from cellulose, polyvinyl alcohol acetal, zein (the main component of zein), mannan, casein, nylon, acrylic resin, and

One or more of oxazoline-modified silicones, the celluloses include one or both of ethyl cellulose and hydroxypropyl cellulose, and the acrylic resin includes polymethacrylic acid resin.

<38><38>

如上述<35>至<37>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片係由上述作用層為支鏈澱粉，上述保護層為乙基纖維素之組合所構成。An oral patch as described in any one of <35> to <37> above, wherein the tooth adhesive patch is composed of a combination of the above active layer being branched starch and the above protective layer being ethyl cellulose.

<39><39>

如上述<1>至<38>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片於上述牙齒黏貼貼片之要貼附於牙齒之面之表面具有凹部。An intraoral patch as described in any one of <1> to <38> above, wherein the tooth adhesive patch has a concave portion on the surface of the tooth adhesive patch to be attached to the tooth.

<40><40>

如上述<39>中記載之口腔內貼片，其中上述剝離片具有凸部，該凸部與藉由對上述剝離片之表面實施之壓紋加工而形成之凹凸對應，且上述凹部與上述凸部對應，將上述剝離片剝離時，殘留於上述牙齒黏貼貼片之貼附面之表面。As described in the above-mentioned <39>, the above-mentioned peelable sheet has a convex portion, and the convex portion corresponds to the concave-convex portion formed by embossing the surface of the above-mentioned peelable sheet, and the above-mentioned concave portion corresponds to the above-mentioned convex portion, and when the above-mentioned peelable sheet is peeled off, the residue remains on the surface of the attachment surface of the above-mentioned tooth adhesive sheet.

<41><41>

如上述<1>至<40>中任一項記載之口腔內貼片，其中上述剝離片之形成材料係選自聚脂肪酸酯、聚碳酸酯、聚丙烯、聚乙烯、聚酯、聚醯胺、聚醯胺醯亞胺、聚醚醚酮、聚醚醯亞胺、聚苯乙烯、聚對苯二甲酸乙二酯、聚氯乙烯、尼龍樹脂、及丙烯酸系樹脂中之1種或2種以上。An oral patch as described in any one of <1> to <40> above, wherein the material forming the peeling sheet is selected from one or more of poly(fatty acid ester), polycarbonate, polypropylene, polyethylene, polyester, polyamide, polyamide imide, polyetheretherketone, polyetherimide, polystyrene, polyethylene terephthalate, polyvinyl chloride, nylon resin, and acrylic resin.

<42><42>

如上述<1>至<41>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片之厚度為35μm以上，較佳為50μm以上，更佳為60μm以上，且為500μm以下，較佳為150μm以下，更佳為70μm以下，且為35μm以上500μm以下，較佳為50μm以上150μm以下，更佳為60μm以上70μm以下。An oral patch as described in any one of <1> to <41> above, wherein the thickness of the tooth adhesive patch is 35 μm or more, preferably 50 μm or more, more preferably 60 μm or more, and 500 μm or less, preferably 150 μm or less, more preferably 70 μm or less, and 35 μm or more and 500 μm or less, preferably 50 μm or more and 150 μm or less, more preferably 60 μm or more and 70 μm or less.

<43><43>

如上述<1>至<42>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片之拉伸強度為20MPa時之應變為2%以上，較佳為3%以上，更佳為4%以上，進而較佳為5%以上。An oral patch as described in any one of <1> to <42> above, wherein the strain of the dental adhesive patch when the tensile strength is 20MPa is 2% or more, preferably 3% or more, more preferably 4% or more, and even more preferably 5% or more.

<44><44>

如上述<1>至<43>中任一項記載之口腔內貼片，其中上述牙齒黏貼貼片之霧值(濁度)為80以下，較佳為70以下，更佳為60以下，進而較佳為50以下。An intraoral patch as described in any one of <1> to <43> above, wherein the haze value (turbidity) of the dental adhesive patch is 80 or less, preferably 70 or less, more preferably 60 or less, and even more preferably 50 or less.

<45><45>

如上述<1>至<44>中任一項記載之口腔內貼片，其由包裝材獨立包裝。An intraoral patch as described in any of the above <1> to <44>, which is independently packaged by packaging materials.

<46><46>

如上述<45>中記載之口腔內貼片，其中上述包裝材將其內部密閉。As described in <45> above, the oral patch, wherein the packaging material seals the interior thereof.

<47><47>

如上述<45>或<46>中記載之口腔內貼片，其中上述包裝材係藉由使用超音波密封、熱密封、或高頻密封將1片或複數片貼片接合而形成。An oral patch as described in <45> or <46> above, wherein the packaging material is formed by joining one or more patches using ultrasonic sealing, heat sealing, or high-frequency sealing.

<48><48>

一種口腔內貼片之使用方法，其係如上述<1>至<47>中任一項記載之口腔內貼片之使用方法，且該使用方法係捏住上述延出部，自上述剝離片剝離上述牙齒黏貼貼片，於捏住上述延出部之狀態下，將上述牙齒黏貼貼片貼附於牙齒表面，將該牙齒黏貼貼片應用於該牙齒表面。A method for using an oral patch, which is the method for using an oral patch as described in any one of <1> to <47> above, and the method for using the patch comprises pinching the extension, peeling off the tooth adhesive patch from the peeling sheet, and attaching the tooth adhesive patch to the tooth surface while pinching the extension, and applying the tooth adhesive patch to the tooth surface.

[產業上之可利用性][Industrial availability]

根據本發明，提供一種使用時操作性優異之口腔內貼片。According to the present invention, an intraoral patch with excellent operability during use is provided.