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SG128403A1 - Tnf-receptors, tnf binding proteins and dnas coding for them - Google Patents

Tnf-receptors, tnf binding proteins and dnas coding for them

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Publication number
SG128403A1
SG128403A1SG1996007006ASG1996007006ASG128403A1SG 128403 A1SG128403 A1SG 128403A1SG 1996007006 ASG1996007006 ASG 1996007006ASG 1996007006 ASG1996007006 ASG 1996007006ASG 128403 A1SG128403 A1SG 128403A1
Authority
SG
Singapore
Prior art keywords
tnf
tnf receptor
binding protein
receptors
binding proteins
Prior art date
Application number
SG1996007006A
Inventor
Rudolf Hauptmann
Adolf Himmler
Ingrid Maurer-Fogy
Christian Stratowa
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen IncfiledCriticalAmgen Inc
Publication of SG128403A1publicationCriticalpatent/SG128403A1/en

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Abstract

DNA sequences coding for a TNF binding protein and for the TNF receptor of which this protein represents the soluble domain. The DNA sequences can be used for the preparation of recombinant DNA molecules for the production of TNF binding protein and TNF receptor. Recombinant TNF-binding protein is used in pharmaceutical preparations for treating indications in the case of which a detrimental effect of TNF is observed. With the aid of the TNF receptor or fragments thereof, or with the aid of suitable host organisms transformed with' recombinant DNA molecules containing the DNA coding for the TNF receptor, or fragments or modifications thereof, substances can be assayed for their interaction with the TNF receptor and/or their impact on the biological activity of TNF. No suitable figure
SG1996007006A1989-04-211990-04-06Tnf-receptors, tnf binding proteins and dnas coding for themSG128403A1 (en)

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
DE3913101ADE3913101A1 (en)1989-04-211989-04-21DNA encoding TNF binding protein and TNF- receptor

Publications (1)

Publication NumberPublication Date
SG128403A1true SG128403A1 (en)2007-01-30

Family

ID=6379124

Family Applications (1)

Application NumberTitlePriority DateFiling Date
SG1996007006ASG128403A1 (en)1989-04-211990-04-06Tnf-receptors, tnf binding proteins and dnas coding for them

Country Status (2)

CountryLink
DE (1)DE3913101A1 (en)
SG (1)SG128403A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
ATE289350T1 (en)1989-04-212005-03-15Amgen Inc TNF RECEPTOR, TNF BINDING PROTEINS AND DNA CODING THEREOF
US6221675B1 (en)1989-04-212001-04-24Amgen, Inc.TNF receptors, TNF binding proteins and DNAs coding for them
US7264944B1 (en)1989-04-212007-09-04Amgen Inc.TNF receptors, TNF binding proteins and DNAs coding for them
US6143866A (en)*1989-07-182000-11-07Amgen, Inc.Tumor necrosis factor (TNF) inhibitor and method for obtaining the same
IL95031A (en)1989-07-182007-03-08Amgen IncMethod for the production of a human recombinant tumor necrosis factor inhibitor

Also Published As

Publication numberPublication date
DE3913101A1 (en)1990-10-31

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