| US296006A (en) | | 1884-04-01 | | John hoefleb |
| AU98530S (en) | 1985-06-20 | 1987-11-05 | Novartis Ag | Subdivided membrane controlled transdermal device |
| US5008110A (en) | 1988-11-10 | 1991-04-16 | The Procter & Gamble Company | Storage-stable transdermal patch |
| ATE220421T1 (en) | 1990-02-26 | 2002-07-15 | Univ Leland Stanford Junior | IDENTIFICATION AND EXPRESSION OF INSECT STEROID RECEPTOR DNA SEQUENCES |
| US6165500A (en) | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
| US6010715A (en) | 1992-04-01 | 2000-01-04 | Bertek, Inc. | Transdermal patch incorporating a polymer film incorporated with an active agent |
| US5364791A (en) | 1992-05-14 | 1994-11-15 | Elisabetta Vegeto | Progesterone receptor having C. terminal hormone binding domain truncations |
| WO1993023431A1 (en) | 1992-05-14 | 1993-11-25 | Baylor College Of Medicine | Mutated steroid hormone receptors, methods for their use and molecular switch for gene therapy |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| US5814618A (en) | 1993-06-14 | 1998-09-29 | Basf Aktiengesellschaft | Methods for regulating gene expression |
| US5464758A (en) | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| IT1261849B (en) | 1993-09-02 | 1996-06-03 | Avantgarde Spa | MEDICAL DEVICE FOR THE ADMINISTRATION OF ACTIVE INGREDIENTS OR VERY LOW DOSAGE DRUGS, IN PARTICULAR HOMEOPATHIC DRUGS. |
| US5902565A (en) | 1993-12-24 | 1999-05-11 | Csl Limited | Spray dried vaccine preparation comprising aluminium adsorbed immunogens |
| US5899880A (en) | 1994-04-08 | 1999-05-04 | Powderject Research Limited | Needleless syringe using supersonic gas flow for particle delivery |
| GB9502879D0 (en) | 1995-02-14 | 1995-04-05 | Oxford Biosciences Ltd | Particle delivery |
| US6013050A (en) | 1995-10-20 | 2000-01-11 | Powderject Research Limited | Particle delivery |
| GB9605690D0 (en) | 1996-03-19 | 1996-05-22 | Oxford Biosciences Ltd | Particle delivery |
| ES2236814T3 (en) | 1996-06-14 | 2005-07-16 | Powderject Vaccines, Inc. | SAMPLE DRIVING MODULE FOR A PARTICLE ACCELERATION DEVICE. |
| US5980948A (en) | 1996-08-16 | 1999-11-09 | Osteotech, Inc. | Polyetherester copolymers as drug delivery matrices |
| WO1999001579A1 (en) | 1997-07-01 | 1999-01-14 | Isis Pharmaceuticals, Inc. | Compositions and methods for the delivery of oligonucleotides via the alimentary canal |
| US5948433A (en) | 1997-08-21 | 1999-09-07 | Bertek, Inc. | Transdermal patch |
| US6051239A (en) | 1997-10-20 | 2000-04-18 | Thomas Jefferson University | Compositions and methods for systemic delivery of oral vaccines and therapeutic agents |
| US5965154A (en) | 1998-03-17 | 1999-10-12 | Plc Holding, L.L.C. | Adhesive matrix type transdermal patch and method of manufacturing same |
| WO2000005252A1 (en)* | 1998-07-22 | 2000-02-03 | Agricultural Research Council | Vaccine comprising a non-toxic immunogenic derivative of clostridium botulinum type d neurotoxin |
| US6776990B2 (en) | 1999-04-08 | 2004-08-17 | Allergan, Inc. | Methods and compositions for the treatment of pancreatitis |
| JP2004512004A (en)* | 1999-05-12 | 2004-04-22 | ユナイテッド ステイツ アーミー メディカル リサーチ アンド マテリエル シーエムディー | Recombinant vaccine against botulinum neurotoxin |
| AU777556B2 (en) | 1999-08-25 | 2004-10-21 | Allergan, Inc. | Activatable recombinant neurotoxins |
| US6306423B1 (en) | 2000-06-02 | 2001-10-23 | Allergan Sales, Inc. | Neurotoxin implant |
| WO2002026191A2 (en) | 2000-09-28 | 2002-04-04 | Nanocyte Inc. | Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue |
| US7255865B2 (en) | 2000-12-05 | 2007-08-14 | Allergan, Inc. | Methods of administering botulinum toxin |
| DE60228723D1 (en)* | 2001-07-27 | 2008-10-16 | Univ Louisiana State | BOTULINUS TOXIN IN THE TREATMENT AND PREVENTION OF ACNE |
| US20040009180A1 (en) | 2002-07-11 | 2004-01-15 | Allergan, Inc. | Transdermal botulinum toxin compositions |
| US7172764B2 (en) | 2003-11-17 | 2007-02-06 | Allergan, Inc. | Rescue agents for treating botulinum toxin intoxications |
| US7598027B2 (en) | 2004-02-24 | 2009-10-06 | Allergan, Inc. | Botulinum toxin screening assays |
| US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| BRPI0508440A (en) | 2004-03-03 | 2007-07-24 | Revance Therapeutics Inc | compositions and methods for topical diagnosis and therapeutic transport |
| SG10201400339VA (en) | 2004-03-03 | 2014-05-29 | Revance Therapeutics Inc | Compositions And Methods For Topical Application And Transdermal Delivery Of Botulinum Toxins |
| JP5089388B2 (en) | 2004-09-01 | 2012-12-05 | アラーガン、インコーポレイテッド | Degradable clostridial toxin |
| US9724287B2 (en) | 2004-11-19 | 2017-08-08 | Metabeauty, Inc. | Optimized skincare regimens for changing the genetic skin type to the ideal skin type—oily, resistant, non-pigmented and tight skin |
| US7727537B2 (en) | 2005-02-14 | 2010-06-01 | Dpm Therapeutics Corp. | Stabilized compositions for topical administration and methods of making same |
| US7838011B2 (en) | 2005-02-14 | 2010-11-23 | Pankaj Modi | Stabilized protein compositions for topical administration and methods of making same |
| RU2007136616A (en) | 2005-03-03 | 2009-04-10 | Риванс Терапьютикс, Инк. (Us) | COMPOSITION AND METHOD FOR LOCAL USE AND PERFORMANCE OF BOTULIN TOXIN |
| EP1869459B1 (en) | 2005-04-05 | 2010-06-09 | Allergan, Inc. | Lipophilic dye-based fret assays for clostridial toxin activity |
| ATE483158T1 (en) | 2005-04-05 | 2010-10-15 | Allergan Inc | CLOSTRIDIAL TOXIN ACTIVITY TESTS |
| US8926991B2 (en) | 2005-06-14 | 2015-01-06 | Botulinum Toxin Research Associates, Inc. | Botulinum toxin and the treatment of primary disorders of mood and affect |
| US8137677B2 (en) | 2005-10-06 | 2012-03-20 | Allergan, Inc. | Non-protein stabilized clostridial toxin pharmaceutical compositions |
| US8168206B1 (en) | 2005-10-06 | 2012-05-01 | Allergan, Inc. | Animal protein-free pharmaceutical compositions |
| AU2006315117A1 (en) | 2005-11-17 | 2007-05-24 | Revance Therapeutics, Inc. | Compositions and methods of topical application and transdermal delivery of botulinum toxins with reduced non-toxin proteins |
| EP2178905B1 (en) | 2007-07-26 | 2013-11-06 | Allergan, Inc. | Methods of activiting clostridial toxins |
| WO2009023549A2 (en)* | 2007-08-09 | 2009-02-19 | University Of Rochester | Vaccine against botulism |
| WO2009042165A2 (en)* | 2007-09-25 | 2009-04-02 | Thomas Jefferson University | Mutant botulinum neurotoxin serotype a polypeptide and uses thereof |
| US9161970B2 (en) | 2007-12-12 | 2015-10-20 | Allergan, Inc. | Dermal filler |
| US9044477B2 (en) | 2007-12-12 | 2015-06-02 | Allergan, Inc. | Botulinum toxin formulation |
| US9107815B2 (en) | 2008-02-22 | 2015-08-18 | Allergan, Inc. | Sustained release poloxamer containing pharmaceutical compositions |
| KR101604515B1 (en) | 2008-03-14 | 2016-03-17 | 알러간, 인코포레이티드 | Immuno-Based Botulinum Toxin Serotype A Activity Assays |
| US20090299328A1 (en) | 2008-05-30 | 2009-12-03 | Allergan, Inc. | Injection device for soft-tissue augmentation fillers, bioactive agents and other biocompatible materials in liquid or gel form |
| CA2770357A1 (en)* | 2009-08-12 | 2011-02-17 | Medical Research Council | Complexing system |
| WO2011146704A1 (en) | 2010-05-20 | 2011-11-24 | Allergan, Inc. | Degradable clostridial toxins |
| US20120195878A1 (en) | 2011-01-28 | 2012-08-02 | Allergan, Inc. | Protocol for the administration of botulinum toxins |
| US8603028B2 (en) | 2011-11-18 | 2013-12-10 | Allergan, Inc. | Injection device having an angled tip portion |
| HUE037310T2 (en)* | 2012-05-30 | 2018-08-28 | Harvard College | Engineered botulinum neurotoxin |
| WO2017063743A1 (en) | 2015-10-14 | 2017-04-20 | Merz Pharma Gmbh & Co. Kgaa | Improvements to ultrasound-based therapy of photoaged tissue |
| HRP20202070T1 (en)* | 2016-05-27 | 2021-02-19 | Ipsen Biopharm Limited | Liquid neurotoxin formulation stabilized with tryptophan or tyrosine |
| KR101824321B1 (en)* | 2016-06-07 | 2018-01-31 | 국방과학연구소 | Botulinum toxin type a vaccine comprising heavy chain c-terminal of botulinum toxin type a mutant inhibiting toxic activity and method thereof |
| GB201621111D0 (en)* | 2016-12-12 | 2017-01-25 | Univ Of Sheffield The | Neurotoxins |