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SG11202005595YA - Antibodies and variants thereof against tigit - Google Patents

Antibodies and variants thereof against tigit

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Publication number
SG11202005595YA
SG11202005595YASG11202005595YASG11202005595YASG11202005595YASG 11202005595Y ASG11202005595Y ASG 11202005595YASG 11202005595Y ASG11202005595Y ASG 11202005595YASG 11202005595Y ASG11202005595Y ASG 11202005595YASG 11202005595Y ASG11202005595Y ASG 11202005595YA
Authority
SG
Singapore
Prior art keywords
antibodies
variants
against tigit
tigit
Prior art date
Application number
SG11202005595YA
Inventor
xinpo Jiang
Shuai Yang
Chuan-Chu Chou
Original Assignee
Nanjing Legend Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Legend Biotech Co LtdfiledCriticalNanjing Legend Biotech Co Ltd
Publication of SG11202005595YApublicationCriticalpatent/SG11202005595YA/en

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SG11202005595YA2018-01-152019-01-15Antibodies and variants thereof against tigitSG11202005595YA (en)

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
CN20180726072018-01-15
PCT/CN2019/071711WO2019137548A1 (en)2018-01-152019-01-15Antibodies and variants thereof against tigit

Publications (1)

Publication NumberPublication Date
SG11202005595YAtrue SG11202005595YA (en)2020-07-29

Family

ID=67219401

Family Applications (1)

Application NumberTitlePriority DateFiling Date
SG11202005595YASG11202005595YA (en)2018-01-152019-01-15Antibodies and variants thereof against tigit

Country Status (11)

CountryLink
US (1)US11708410B2 (en)
EP (1)EP3740508A4 (en)
JP (1)JP7316284B2 (en)
KR (1)KR20200109313A (en)
CN (1)CN111601826B (en)
AU (1)AU2019207296A1 (en)
CA (1)CA3088332A1 (en)
IL (1)IL275737A (en)
SG (1)SG11202005595YA (en)
TW (1)TW201932489A (en)
WO (1)WO2019137548A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
DK3618863T3 (en)2017-05-012023-08-21Agenus Inc ANTI-TIGIT ANTIBODIES AND METHODS OF USING THEREOF
KR20210108978A (en)2018-12-212021-09-03오제 이뮈노테라프틱스 Bifunctional Anti-PD-1/IL-7 Molecules
WO2020165374A1 (en)2019-02-142020-08-20Ose ImmunotherapeuticsBifunctional molecule comprising il-15ra
WO2021122866A1 (en)2019-12-172021-06-24Ose ImmunotherapeuticsBifunctional molecules comprising an il-7 variant
CA3176497A1 (en)2020-05-072021-11-11Fatima MECHTA-GRIGORIOUAntxr1 as a biomarker of immunosuppressive fibroblast populations and its use for predicting response to immunotherapy
CN111995681B (en)*2020-05-092022-03-08华博生物医药技术(上海)有限公司anti-TIGIT antibody, preparation method and application thereof
KR20230024368A (en)2020-06-182023-02-20제넨테크, 인크. Treatment with anti-TIGIT antibodies and PD-1 axis binding antagonists
TW202216778A (en)2020-07-152022-05-01美商安進公司Tigit and cd112r blockade
CN114539405B (en)*2020-11-232024-02-23广东菲鹏制药股份有限公司anti-TIGIT antibodies or antigen-binding fragments thereof
WO2022112198A1 (en)2020-11-242022-06-02Worldwide Innovative NetworkMethod to select the optimal immune checkpoint therapies
WO2022148781A1 (en)2021-01-052022-07-14Institut CurieCombination of mcoln activators and immune checkpoint inhibitors
EP4320156A1 (en)2021-04-092024-02-14Ose ImmunotherapeuticsScaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains
MX2023011964A (en)2021-04-092024-01-08Ose ImmunotherapeuticsNew scaffold for bifunctional molecules with improved properties.
AR125753A1 (en)2021-05-042023-08-09Agenus Inc ANTI-TIGIT ANTIBODIES, ANTI-CD96 ANTIBODIES AND METHODS OF USE OF THESE
CN115466327B (en)*2021-06-102025-07-08北京天广实生物技术股份有限公司 Antibodies that bind to TIGIT and uses thereof
JP2024527049A (en)2021-07-282024-07-19ジェネンテック, インコーポレイテッド Methods and Compositions for Treating Cancer
WO2023056403A1 (en)2021-09-302023-04-06Genentech, Inc.Methods for treatment of hematologic cancers using anti-tigit antibodies, anti-cd38 antibodies, and pd-1 axis binding antagonists
CN118591557A (en)*2022-01-242024-09-03原启生物科技(上海)有限责任公司 Antigen binding proteins targeting TIGIT and uses thereof
KR20250022049A (en)2022-06-072025-02-14제넨테크, 인크. Method for determining the efficacy of a treatment for lung cancer comprising an anti-PD-L1 antagonist and an anti-TIGIT antagonist antibody
WO2024003360A1 (en)2022-07-012024-01-04Institut CurieBiomarkers and uses thereof for the treatment of neuroblastoma
JP2025525886A (en)2022-08-022025-08-07オーエスイー・イミュノセラピューティクス Multifunctional molecules against CD28
WO2024041639A1 (en)*2022-08-262024-02-29Nanjing Legend Biotech Co., Ltd.Antibodies targeting tigit and uses thereof
CN116444653B (en)*2023-03-092024-03-15中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心)Preparation and application of blocking African swine fever virus monoclonal antibody hybridoma cell strain
WO2024200826A1 (en)2023-03-302024-10-03Ose ImmunotherapeuticsLipid-based nanoparticle targeted at activated immune cells for the expression of immune cell inhibiting molecule and use thereof
WO2024200823A1 (en)2023-03-302024-10-03Ose ImmunotherapeuticsLipid-based nanoparticle targeted at activated immune cells for the expression of immune cell enhancing molecule and use thereof
WO2025002151A1 (en)*2023-06-272025-01-02正大天晴药业集团股份有限公司Anti-tigit antibodies and use thereof
WO2025068461A1 (en)2023-09-292025-04-03Negio TherapeuticsGuanfacine derivatives and their use in treating cancer
WO2025068452A1 (en)2023-09-292025-04-03Negio TherapeuticsGuanfacine derivatives and their use in treating cancer
WO2025132831A1 (en)2023-12-192025-06-26Universite D'aix-MarseilleN-heteroaryl derivatives and uses thereof for treating cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
CN103073644B (en)2012-12-312014-03-12中国科学技术大学Specific anti-mouse TIGIT monoclonal antibody and preparation method, identification and application thereof
CA2953245A1 (en)*2014-07-162016-01-21Genentech, Inc.Methods of treating cancer using tigit inhibitors and anti-cancer agents
MD4733C1 (en)*2014-08-192021-07-31Merck Sharp & Dohme Corp Anti-TIGIT antibodies
CA3138083A1 (en)*2014-12-222016-06-30Systimmune, Inc.Bispecific tetravalent antibodies and methods of making and using thereof
KR102644115B1 (en)*2014-12-232024-03-05브리스톨-마이어스 스큅 컴퍼니Antibodies to tigit
TWI715587B (en)*2015-05-282021-01-11美商安可美德藥物股份有限公司Tigit-binding agents and uses thereof
PE20181292A1 (en)*2015-08-202018-08-07Abbvie Stemcentrx Llc ANTI-DLL3-DRUG ANTIBODY CONJUGATES AND METHODS OF USE
TWI811892B (en)*2015-09-252023-08-11美商建南德克公司Anti-tigit antibodies and methods of use
DK3356413T3 (en)*2015-10-012022-04-11Potenza Therapeutics Inc ANTI-TIGIT ANTIGEN BINDING PROTEINS AND METHODS FOR USING IT
EP3565839A4 (en)*2017-01-052021-04-21Gensun Biopharma Inc. CHECKPOINT REGULATOR ANTAGONISTS

Also Published As

Publication numberPublication date
KR20200109313A (en)2020-09-22
CN111601826A (en)2020-08-28
AU2019207296A1 (en)2020-07-16
EP3740508A1 (en)2020-11-25
IL275737A (en)2020-08-31
CA3088332A1 (en)2019-07-18
EP3740508A4 (en)2022-03-23
JP7316284B2 (en)2023-07-27
CN111601826B (en)2023-12-15
JP2021510710A (en)2021-04-30
TW201932489A (en)2019-08-16
US20210095028A1 (en)2021-04-01
US11708410B2 (en)2023-07-25
WO2019137548A1 (en)2019-07-18

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