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SG11202002982YA - Multispecific antibody - Google Patents

Multispecific antibody

Info

Publication number
SG11202002982YA
SG11202002982YASG11202002982YASG11202002982YASG11202002982YASG 11202002982Y ASG11202002982Y ASG 11202002982YASG 11202002982Y ASG11202002982Y ASG 11202002982YASG 11202002982Y ASG11202002982Y ASG 11202002982YASG 11202002982Y ASG11202002982Y ASG 11202002982YA
Authority
SG
Singapore
Prior art keywords
multispecific antibody
multispecific
antibody
Prior art date
Application number
SG11202002982YA
Inventor
David Urech
Tea Gunde
Sebastian Meyer
Matthias Brock
Christian Hess
Alexandre Simonin
Stefan Warmuth
Original Assignee
Numab Therapeutics AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP17195779.8Aexternal-prioritypatent/EP3470426A1/en
Application filed by Numab Therapeutics AGfiledCriticalNumab Therapeutics AG
Publication of SG11202002982YApublicationCriticalpatent/SG11202002982YA/en

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SG11202002982YA2017-10-102018-10-09Multispecific antibodySG11202002982YA (en)

Applications Claiming Priority (5)

Application NumberPriority DateFiling DateTitle
EP17195779.8AEP3470426A1 (en)2017-10-102017-10-10Multispecific antibody
EP181504652018-01-05
EP181670932018-04-12
EP181808142018-06-29
PCT/EP2018/077509WO2019072868A1 (en)2017-10-102018-10-09Multispecific antibody

Publications (1)

Publication NumberPublication Date
SG11202002982YAtrue SG11202002982YA (en)2020-04-29

Family

ID=63799025

Family Applications (1)

Application NumberTitlePriority DateFiling Date
SG11202002982YASG11202002982YA (en)2017-10-102018-10-09Multispecific antibody

Country Status (16)

CountryLink
US (1)US12202911B2 (en)
EP (1)EP3694873A1 (en)
JP (1)JP7442443B2 (en)
KR (1)KR20200063155A (en)
CN (1)CN111194323B (en)
AU (1)AU2018348429A1 (en)
BR (1)BR112020006999A2 (en)
CA (1)CA3075969A1 (en)
CL (2)CL2020000937A1 (en)
CO (1)CO2020003882A2 (en)
IL (1)IL273576A (en)
MA (1)MA50352A (en)
MX (1)MX2020003562A (en)
SG (1)SG11202002982YA (en)
WO (1)WO2019072868A1 (en)
ZA (1)ZA202001294B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
MX2019009967A (en)2017-02-242019-12-02Macrogenics IncBispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof.
JP7130678B2 (en)*2017-06-052022-09-05ヌマブ セラピューティクス アクチェンゲゼルシャフト Novel anti-HSA antibody
CA3075337A1 (en)*2017-10-102019-04-18Numab Therapeutics AGAntibodies targeting cd137 and methods of use thereof
US12077595B2 (en)*2017-11-132024-09-03Crescendo Biologics LimitedSingle domain antibodies that bind to CD137
TWI839395B (en)*2018-10-092024-04-21瑞士商Numab治療公司Antibodies targeting cd137 and methods of use thereof
WO2021013142A1 (en)*2019-07-222021-01-28江苏恒瑞医药股份有限公司Anti-4-1bb antibody, antigen-binding fragment thereof, and bispecific antibody
US11466086B2 (en)2019-10-112022-10-11Nanjing Leads Biolabs Co., Ltd.Antibodies binding 4-1BB and uses thereof
EP3816185A1 (en)*2019-11-042021-05-05Numab Therapeutics AGMultispecific antibody directed against pd-l1 and a tumor-associated antigen
KR20220107251A (en)*2020-01-092022-08-02에프. 호프만-라 로슈 아게 Novel 4-1BBL Trimer-Containing Antigen Binding Molecules
WO2021236658A1 (en)2020-05-192021-11-25Boehringer Ingelheim International GmbhBinding molecules for the treatment of cancer
CN114195900B (en)*2020-09-172024-02-23普米斯生物技术(珠海)有限公司Anti-4-1 BB/PD-L1 bispecific antibody and application thereof
EP3988568A1 (en)2020-10-212022-04-27Numab Therapeutics AGCombination treatment
WO2022136693A1 (en)2020-12-232022-06-30Numab Therapeutics AGAntibody variable domains and antibodies having decreased immunogenicity
WO2023001987A2 (en)2021-07-222023-01-26University Of DundeeTherapeutic muteins
KR20250008754A (en)2022-05-062025-01-15누맙 세러퓨틱스 아게 Antibody variable domains and antibodies with reduced immunogenicity
EP4273162A1 (en)2022-05-062023-11-08Numab Therapeutics AGAntibody variable domains and antibodies having decreased immunogenicity
WO2024240690A2 (en)2023-05-192024-11-28Numab Therapeutics AGAntibody variable domains and antibodies having decreased immunogenicity

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US4458066A (en)1980-02-291984-07-03University Patents, Inc.Process for preparing polynucleotides
EP0138854B1 (en)1983-03-081992-11-04Chiron Mimotopes Pty. Ltd.Antigenically active amino acid sequences
US5225539A (en)1986-03-271993-07-06Medical Research CouncilRecombinant altered antibodies and methods of making altered antibodies
US4881175A (en)1986-09-021989-11-14Genex CorporationComputer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
US5260203A (en)1986-09-021993-11-09Enzon, Inc.Single polypeptide chain binding molecules
US5013653A (en)1987-03-201991-05-07Creative Biomolecules, Inc.Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage
US5132405A (en)1987-05-211992-07-21Creative Biomolecules, Inc.Biosynthetic antibody binding sites
US5091513A (en)1987-05-211992-02-25Creative Biomolecules, Inc.Biosynthetic antibody binding sites
US5258498A (en)1987-05-211993-11-02Creative Biomolecules, Inc.Polypeptide linkers for production of biosynthetic proteins
DE3853515T3 (en)1987-05-212005-08-25Micromet Ag MULTIFUNCTIONAL PROTEINS WITH SPECIFIC OBJECTIVES.
US5530101A (en)1988-12-281996-06-25Protein Design Labs, Inc.Humanized immunoglobulins
DE3920358A1 (en)1989-06-221991-01-17Behringwerke Ag BISPECIFIC AND OLIGO-SPECIFIC, MONO- AND OLIGOVALENT ANTI-BODY CONSTRUCTS, THEIR PRODUCTION AND USE
SE509359C2 (en)1989-08-011999-01-18Cemu Bioteknik Ab Use of stabilized protein or peptide conjugates for the preparation of a drug
US6267964B1 (en)1989-08-012001-07-31Affibody Technology Sweden AbStabilized protein or peptide conjugates able to bond albumin having extended biological half-lives
US6150584A (en)1990-01-122000-11-21Abgenix, Inc.Human antibodies derived from immunized xenomice
US6075181A (en)1990-01-122000-06-13Abgenix, Inc.Human antibodies derived from immunized xenomice
GB9114948D0 (en)1991-07-111991-08-28Pfizer LtdProcess for preparing sertraline intermediates
CA2507749C (en)1991-12-132010-08-24Xoma CorporationMethods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
DE19819846B4 (en)1998-05-052016-11-24Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Multivalent antibody constructs
EP2180054A1 (en)1999-12-242010-04-28Genentech, Inc.Methods and compositions for prolonging elimination half-times of bioactive compounds
AU2002335930B2 (en)2001-03-092005-07-28Morphosys AgSerum albumin binding moieties
US20030157561A1 (en)*2001-11-192003-08-21Kolkman Joost A.Combinatorial libraries of monomer domains
ES2307832T3 (en)2001-12-032008-12-01Amgen Fremont Inc. ANTIBODY CLASSIFICATION BASED ON THE CHARACTERISTICS OF UNION.
CA2490009A1 (en)2002-06-212003-12-31Dyax CorporationSerum protein-associated target-specific ligands and identification method therefor
US9321832B2 (en)2002-06-282016-04-26Domantis LimitedLigand
DE60305919T2 (en)2002-06-282007-01-18Domantis Limited, Cambridge DUAL SPECIFIC LIGANDS WITH INCREASED HALF TIME
WO2004010947A2 (en)2002-07-302004-02-05Bristol-Myers Squibb CompanyHumanized antibodies against human 4-1bb
US7217797B2 (en)2002-10-152007-05-15Pdl Biopharma, Inc.Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
JP2006504971A (en)2002-11-012006-02-09ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・コロラド,ア・ボディー・コーポレイト Quantitative analysis of protein isoforms by matrix-assisted laser desorption ionization-time-of-flight mass spectrometry
KR20070039911A (en)2004-06-012007-04-13도만티스 리미티드 Bispecific Fusion Antibodies with Enhanced Serum Half-Life
EP2769990A3 (en)2004-12-022015-02-25Domantis LimitedBispecific domain antibodies targeting serum albumin and GLP-1 or PYY
KR101888321B1 (en)2005-07-012018-08-13이. 알. 스퀴부 앤드 선즈, 엘.엘.씨.Human monoclonal antibodies to programmed death ligand 1(pd-l1)
JP5602625B2 (en)2007-06-262014-10-08エフ−スター ビオテヒノロギッシェ フォルシュングス− ウント エントヴィッケルングスゲゼルシャフト ミット ベシュレンクテル ハフツング Binding substance display
CA2700714C (en)2007-09-262018-09-11Ucb Pharma S.A.Dual specificity antibody fusions
SI2334705T1 (en)2008-09-262017-05-31Ucb Biopharma SprlBiological products
SG196798A1 (en)2008-12-092014-02-13Genentech IncAnti-pd-l1 antibodies and their use to enhance t-cell function
EP2454285A2 (en)2009-07-162012-05-23Glaxo Group LimitedImproved anti-serum albumin binding single variable domains
HUE037159T2 (en)2009-11-242018-08-28Medimmune Ltd Targeted Binding Agents Against B7-H1
GB201000467D0 (en)2010-01-122010-02-24Ucb Pharma SaAntibodies
KR101527297B1 (en)2010-09-092015-06-26화이자 인코포레이티드4-1bb binding molecules
SI2785375T1 (en)2011-11-282020-11-30Merck Patent GmbhAnti-pd-l1 antibodies and uses thereof
MA41044A (en)*2014-10-082017-08-15Novartis Ag COMPOSITIONS AND METHODS OF USE FOR INCREASED IMMUNE RESPONSE AND CANCER TREATMENT
MX384025B (en)*2014-11-262025-03-14Xencor Inc HETERODIMERIC ANTIBODIES THAT BIND TO CD3 AND TUMOR ANTIGENS.
WO2016134358A1 (en)*2015-02-222016-08-25Sorrento Therapeutics, Inc.Antibody therapeutics that bind cd137
CA2978942A1 (en)*2015-03-132016-09-22Cytomx Therapeutics, Inc.Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof
EA201890041A1 (en)2015-06-152018-07-31Нумаб Инновейшн Аг HETERODIMERNY POLYSPECIFIC ANTIBODY FORMAT
WO2017102835A1 (en)*2015-12-142017-06-22Complix NvBinding molecule comprising an alphabody-polypeptide and an antibody
BR112018013677A2 (en)*2016-01-112019-01-22Inhibrx Inc multivalent and multispecific 41bb binding fusion proteins
CA3075337A1 (en)*2017-10-102019-04-18Numab Therapeutics AGAntibodies targeting cd137 and methods of use thereof
MA50353A (en)*2017-10-102020-08-19Numab Therapeutics AG TARGETING ANTIBODIES PDL1 AND ASSOCIATED METHODS OF USE

Also Published As

Publication numberPublication date
US20230192897A1 (en)2023-06-22
CL2020000937A1 (en)2020-09-25
IL273576A (en)2020-05-31
WO2019072868A1 (en)2019-04-18
ZA202001294B (en)2024-08-28
MX2020003562A (en)2020-10-01
EP3694873A1 (en)2020-08-19
CN111194323B (en)2024-07-09
CL2021000028A1 (en)2021-05-28
CO2020003882A2 (en)2020-05-29
KR20200063155A (en)2020-06-04
BR112020006999A2 (en)2020-10-06
JP2021501744A (en)2021-01-21
CA3075969A1 (en)2019-04-18
JP7442443B2 (en)2024-03-04
AU2018348429A1 (en)2020-03-12
MA50352A (en)2020-08-19
CN111194323A (en)2020-05-22
US12202911B2 (en)2025-01-21

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