| US20170151281A1 (en) | 2015-02-19 | 2017-06-01 | Batu Biologics, Inc. | Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer |
| EP3295951B1 (en) | 2015-02-19 | 2020-04-22 | Compugen Ltd. | Anti-pvrig antibodies and methods of use |
| UA125638C2 (en) | 2015-08-07 | 2022-05-11 | Ейелікс Онколоджи Інк. | Constructs having a sirp-alpha domain or variant thereof |
| US11649284B2 (en)* | 2016-04-18 | 2023-05-16 | Baylor College Of Medicine | Cancer gene therapy targeting CD47 |
| CN106084052B (en)* | 2016-06-17 | 2019-12-27 | 长春金赛药业股份有限公司 | anti-CD 47 monoclonal antibody and application thereof |
| EA201990218A1 (en) | 2016-07-06 | 2019-07-31 | Селджин Корпорейшн | ANTIBODIES WITH LOW IMMUNOGENITY AND THEIR APPLICATION |
| CA3040440C (en)* | 2016-07-15 | 2022-12-13 | Korea Institute Of Science And Technology | A novel nanocage and use thereof |
| CN108738313B (en)* | 2016-10-20 | 2022-12-30 | 天境生物科技(上海)有限公司 | Novel CD47 monoclonal antibody and application thereof |
| WO2018081898A1 (en) | 2016-11-03 | 2018-05-11 | Trillium Therapeutics Inc. | Improvements in cd47 blockade therapy by hdac inhibitors |
| SG11202000053TA (en) | 2017-08-02 | 2020-02-27 | Phanes Therapeutics Inc | Anti-cd47 antibodies and uses thereof |
| PT3587445T (en)* | 2017-08-10 | 2024-03-14 | Grifols Diagnostic Solutions Inc | An oligomerization tag comprising an immunoglobulin fc region and a polyhis domain |
| BR112020003306A2 (en) | 2017-08-18 | 2020-08-25 | Ultrahuman Four Limited | bonding agents |
| EP3710048A4 (en)* | 2017-11-17 | 2021-08-18 | University of Massachusetts | HUMANIZED MONOCLONAL 2C7 ANTIBODIES AGAINST ANEISSERIA GONORRHOEAE |
| MX2020005463A (en) | 2017-12-01 | 2020-09-07 | Seattle Genetics Inc | Cd47 antibodies and uses thereof for treating cancer. |
| CN110144009B (en)* | 2018-02-14 | 2020-01-21 | 上海洛启生物医药技术有限公司 | CD47 single domain antibodies and uses thereof |
| GB201804860D0 (en)* | 2018-03-27 | 2018-05-09 | Ultrahuman Two Ltd | CD47 Binding agents |
| CN110577597B (en)* | 2018-06-11 | 2021-10-22 | 康诺亚生物医药科技（成都）有限公司 | Antibody for blocking interaction between CD47 and SIRP alpha |
| US11634490B2 (en) | 2018-06-15 | 2023-04-25 | Accurus Biosciences, Inc. | Blocking antibodies against CD47 and methods of use thereof |
| CN109053882B (en)* | 2018-08-28 | 2019-08-23 | 东莞市朋志生物科技有限公司 | A kind of binding protein of NS1 albumen and application |
| JP7583707B2 (en)* | 2018-08-31 | 2024-11-14 | 南京聖和薬業股▲ふん▼有限公司 | Anti-CD47 antibodies and their applications |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| WO2020097193A1 (en) | 2018-11-06 | 2020-05-14 | The Regents Of The University Of California | Chimeric antigen receptors for phagocytosis |
| MX2021010265A (en) | 2019-02-26 | 2021-09-23 | Janssen Biotech Inc | Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies. |
| US10858442B2 (en) | 2019-04-18 | 2020-12-08 | Qlsf Biotherapeutics Inc. | Antibodies that target human CD47 |
| US11013764B2 (en) | 2019-04-30 | 2021-05-25 | Myeloid Therapeutics, Inc. | Engineered phagocytic receptor compositions and methods of use thereof |
| WO2020230091A1 (en) | 2019-05-14 | 2020-11-19 | Janssen Biotech, Inc. | Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors |
| CN119700932A (en) | 2019-05-31 | 2025-03-28 | Alx肿瘤生物技术公司 | Methods of treating cancer with sirpa Fc fusions in combination with immune checkpoint inhibitors |
| CN114206912B (en) | 2019-06-07 | 2025-02-11 | Alx肿瘤生物技术公司 | Methods and reagents for reducing interference from drugs that bind CD47 in serological assays |
| AU2020315598B2 (en) | 2019-07-16 | 2024-12-12 | Gilead Sciences, Inc. | HIV vaccines and methods of making and using |
| CN114981409A (en) | 2019-09-03 | 2022-08-30 | 美洛德生物医药公司 | Methods and compositions for genomic integration |
| TW202124450A (en) | 2019-10-18 | 2021-07-01 | 美商四十七股份有限公司 | Combination therapies for treating myelodysplastic syndromes and acute myeloid leukemia |
| KR20220103959A (en)* | 2019-10-25 | 2022-07-25 | 우시 바이올로직스 아일랜드 리미티드 | Novel anti-CD47 antibodies and uses thereof |
| JP2022552748A (en) | 2019-10-31 | 2022-12-19 | フォーティ セブン， インコーポレイテッド | Treatment of hematological cancers with anti-CD47 and anti-CD20 |
| GB201918230D0 (en) | 2019-12-11 | 2020-01-22 | Prec Therapeutics Ltd | Antibodies and their uses |
| US10980836B1 (en) | 2019-12-11 | 2021-04-20 | Myeloid Therapeutics, Inc. | Therapeutic cell compositions and methods of manufacturing and use thereof |
| CA3165735A1 (en) | 2019-12-24 | 2021-07-01 | Carna Biosciences, Inc. | Diacylglycerol kinase modulating compounds |
| JOP20220184A1 (en) | 2020-02-12 | 2023-01-30 | Janssen Biotech Inc | TREATMENT OF PATIENTS HAVING c-MET EXON 14 SKIPPING MUTATIONS |
| JP7522841B2 (en) | 2020-02-14 | 2024-07-25 | ギリアード サイエンシーズ， インコーポレイテッド | Antibodies and fusion proteins that bind to CCR8 and uses thereof |
| US12091681B2 (en) | 2020-03-27 | 2024-09-17 | Mendus B.V. | Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy |
| WO2022022662A1 (en)* | 2020-07-31 | 2022-02-03 | 百奥泰生物制药股份有限公司 | Cd47 antibody and application thereof |
| US20240016787A1 (en) | 2020-11-03 | 2024-01-18 | Rdiscovery, LLC | Methods for treatment of cancer and phagocytosis-deficiency related diseases |
| WO2022098905A2 (en) | 2020-11-04 | 2022-05-12 | Myeloid Therapeutics, Inc. | Engineered chimeric fusion protein compositions and methods of use thereof |
| US20220196651A1 (en) | 2020-12-06 | 2022-06-23 | ALX Oncology Inc. | Multimers for reducing the interference of drugs that bind cd47 in serological assays |
| WO2022148383A1 (en)* | 2021-01-05 | 2022-07-14 | National Institute Of Biological Sciences, Beijing | A bispecific antibody targeting gpc3 and cd47 |
| KR20230129481A (en)* | 2021-01-08 | 2023-09-08 | 베이징 한미 파마슈티컬 컴퍼니 리미티드 | Antibodies and antigen-binding fragments that specifically bind to CD47 |
| CA3212351A1 (en) | 2021-03-12 | 2022-09-15 | Mendus B.V. | Methods of vaccination and use of cd47 blockade |
| AU2022237618A1 (en) | 2021-03-17 | 2023-10-12 | Myeloid Therapeutics, Inc. | Engineered chimeric fusion protein compositions and methods of use thereof |
| TW202302145A (en) | 2021-04-14 | 2023-01-16 | 美商基利科學股份有限公司 | Co-inhibition of cd47/sirpα binding and nedd8-activating enzyme e1 regulatory subunit for the treatment of cancer |
| IL308445A (en) | 2021-05-11 | 2024-01-01 | Myeloid Therapeutics Inc | Methods and compositions for genomic integration |
| IL308400A (en) | 2021-05-13 | 2024-01-01 | Alx Oncology Inc | Combination therapies for treating cancer |
| AU2022298639B2 (en) | 2021-06-23 | 2024-11-07 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| EP4359415A1 (en) | 2021-06-23 | 2024-05-01 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| US11926628B2 (en) | 2021-06-23 | 2024-03-12 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| WO2022271677A1 (en) | 2021-06-23 | 2022-12-29 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| CN117881698A (en)* | 2021-06-30 | 2024-04-12 | 创新生物有限公司 | Humanized antibody having specificity for CD47 and pharmaceutical composition for preventing or treating CD 47-associated disease comprising the same |
| WO2023076983A1 (en) | 2021-10-28 | 2023-05-04 | Gilead Sciences, Inc. | Pyridizin-3(2h)-one derivatives |
| IL312107A (en) | 2021-10-29 | 2024-06-01 | Gilead Sciences Inc | Cd73 compounds |
| KR20240123836A (en) | 2021-12-22 | 2024-08-14 | 길리애드 사이언시즈, 인코포레이티드 | Icarus zinc finger family decomposers and their uses |
| EP4452415A1 (en) | 2021-12-22 | 2024-10-30 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
| CN114371282A (en)* | 2021-12-30 | 2022-04-19 | 上海药明生物医药有限公司 | A method for evaluating the effect of antigen silencing effect on antibody efficacy and its application |
| TW202340168A (en) | 2022-01-28 | 2023-10-16 | 美商基利科學股份有限公司 | Parp7 inhibitors |
| EP4493554A1 (en) | 2022-03-17 | 2025-01-22 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
| KR20240165995A (en) | 2022-03-24 | 2024-11-25 | 길리애드 사이언시즈, 인코포레이티드 | Combination therapy for the treatment of TROP-2 expressing cancers |
| TWI876305B (en) | 2022-04-05 | 2025-03-11 | 美商基利科學股份有限公司 | Combination therapy for treating colorectal cancer |
| WO2023205719A1 (en) | 2022-04-21 | 2023-10-26 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| EP4547657A1 (en) | 2022-07-01 | 2025-05-07 | Gilead Sciences, Inc. | Cd73 compounds |
| KR20250036855A (en) | 2022-07-12 | 2025-03-14 | 길리애드 사이언시즈, 인코포레이티드 | HIV immunogenic polypeptides and vaccines, and uses thereof |
| WO2024064668A1 (en) | 2022-09-21 | 2024-03-28 | Gilead Sciences, Inc. | FOCAL IONIZING RADIATION AND CD47/SIRPα DISRUPTION ANTICANCER COMBINATION THERAPY |
| WO2024121777A1 (en) | 2022-12-09 | 2024-06-13 | Pfizer Inc. | Cd47 blocking agent and anti-bcma / anti-cd3 bispecific antibody combination therapy |
| WO2024124107A2 (en) | 2022-12-09 | 2024-06-13 | Pfizer Inc. | Cd47 blocking agent and anti-cd20 / anti-cd3 bispecific antibody combination therapy |
| CN118221812A (en)* | 2022-12-14 | 2024-06-21 | 上海迈石生物技术有限公司 | CD 47-targeted monoclonal antibody and application thereof |
| WO2024137852A1 (en) | 2022-12-22 | 2024-06-27 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| WO2024140993A2 (en)* | 2022-12-29 | 2024-07-04 | Shanghai Henlius Biotech, Inc. | Anti-cd47 antibodies and methods of use |
| WO2024189544A1 (en) | 2023-03-13 | 2024-09-19 | Janssen Biotech, Inc. | Combination therapies with bi-specific anti-egfr/c-met antibodies and anti-pd-1 antibodies |
| US20240383922A1 (en) | 2023-04-11 | 2024-11-21 | Gilead Sciences, Inc. | KRAS Modulating Compounds |
| WO2024220917A1 (en) | 2023-04-21 | 2024-10-24 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| WO2025006720A1 (en) | 2023-06-30 | 2025-01-02 | Gilead Sciences, Inc. | Kras modulating compounds |
| WO2025024811A1 (en) | 2023-07-26 | 2025-01-30 | Gilead Sciences, Inc. | Parp7 inhibitors |
| US20250066328A1 (en) | 2023-07-26 | 2025-02-27 | Gilead Sciences, Inc. | Parp7 inhibitors |
| US20250109147A1 (en) | 2023-09-08 | 2025-04-03 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| WO2025054347A1 (en) | 2023-09-08 | 2025-03-13 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| US20250154172A1 (en) | 2023-11-03 | 2025-05-15 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |