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SG11201604706TA - Stabilized pharmaceutical formulations of insulin aspart - Google Patents

Stabilized pharmaceutical formulations of insulin aspart

Info

Publication number
SG11201604706TA
SG11201604706TASG11201604706TASG11201604706TASG11201604706TASG 11201604706T ASG11201604706T ASG 11201604706TASG 11201604706T ASG11201604706T ASG 11201604706TASG 11201604706T ASG11201604706T ASG 11201604706TASG 11201604706T ASG11201604706T ASG 11201604706TA
Authority
SG
Singapore
Prior art keywords
pharmaceutical formulations
insulin aspart
stabilized pharmaceutical
stabilized
aspart
Prior art date
Application number
SG11201604706TA
Inventor
Oliver Bley
Petra Loos
Bernd Bidlingmaier
Walter Kamm
Harald Berchtold
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SafiledCriticalSanofi Sa
Publication of SG11201604706TApublicationCriticalpatent/SG11201604706TA/en

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SG11201604706TA2014-01-092015-01-08Stabilized pharmaceutical formulations of insulin aspartSG11201604706TA (en)

Applications Claiming Priority (3)

Application NumberPriority DateFiling DateTitle
US201461925472P2014-01-092014-01-09
EP143050232014-01-09
PCT/EP2015/050215WO2015104310A1 (en)2014-01-092015-01-08Stabilized pharmaceutical formulations of insulin aspart

Publications (1)

Publication NumberPublication Date
SG11201604706TAtrue SG11201604706TA (en)2016-07-28

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Family Applications (1)

Application NumberTitlePriority DateFiling Date
SG11201604706TASG11201604706TA (en)2014-01-092015-01-08Stabilized pharmaceutical formulations of insulin aspart

Country Status (12)

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US (3)US9895423B2 (en)
EP (1)EP3091964A1 (en)
JP (2)JP6735674B2 (en)
KR (1)KR20160101195A (en)
CN (2)CN114939156A (en)
AU (1)AU2015205620A1 (en)
BR (1)BR112016015851A2 (en)
CA (1)CA2932873A1 (en)
MX (1)MX2016008977A (en)
RU (1)RU2016132340A (en)
SG (1)SG11201604706TA (en)
WO (1)WO2015104310A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
TWI641381B (en)2013-02-042018-11-21法商賽諾菲公司 Stabilized pharmaceutical formulations of insulin analogs and/or insulin derivatives
TW201605489A (en)*2013-10-252016-02-16賽諾菲公司Stable formulation of INSULIN GLULISINE
JP6641280B2 (en)2014-01-092020-02-05サノフイSanofi Stabilized pharmaceutical formulations of insulin analogues and / or insulin derivatives
JP2020143105A (en)*2014-01-092020-09-10サノフイSanofiStabilized pharmaceutical formulations of insulin aspart
MX2016008977A (en)*2014-01-092016-10-04Sanofi SaStabilized pharmaceutical formulations of insulin aspart.
CN105899191B (en)*2014-01-092020-06-16赛诺菲Stabilized glycerol-free pharmaceutical formulations of insulin analogues and/or insulin derivatives
GB201607918D0 (en)*2016-05-062016-06-22Arecor LtdNovel formulations
ES2954180T3 (en)*2016-09-292023-11-20Arecor Ltd Pharmaceutical formulation comprising an insulin compound
JP7527984B2 (en)*2018-03-162024-08-05アンジ ファーマシューティカルズ インコーポレーテッド Compositions and methods for treating severe constipation
EP3773474A1 (en)2018-04-042021-02-17Arecor LimitedMedical infusion pump system for the delivery of an insulin compound
CN114306577B (en)*2020-10-102024-04-09南京汉欣医药科技有限公司Preparation method of insulin aspart 30 suspension
US20240299552A1 (en)*2020-12-162024-09-12Zealand Pharma A/SPharmaceutical Composition of GLP-1/GLP-2 Dual Agonists
CN113896784B (en)*2021-10-182024-04-16合肥天麦生物科技发展有限公司Preparation method of insulin crystal and product thereof

Family Cites Families (157)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
GB835638A (en)1956-12-011960-05-25Novo Terapeutisk Labor AsInsulin crystal suspensions having a protracted effect
GB840870A (en)1957-08-031960-07-13Novo Terapeutisk Labor AsImprovements in or relating to insulin preparations
JPS6033474B2 (en)1978-05-111985-08-02藤沢薬品工業株式会社 Novel hyaluronidase BMP-8231 and its production method
PH25772A (en)1985-08-301991-10-18Novo Industri AsInsulin analogues, process for their preparation
CA1275922C (en)*1985-11-281990-11-06Harunobu AmagaseTreatment of cancer
US5614492A (en)1986-05-051997-03-25The General Hospital CorporationInsulinotropic hormone GLP-1 (7-36) and uses thereof
DK257988D0 (en)1988-05-111988-05-11Novo Industri As NEW PEPTIDES
DE3837825A1 (en)1988-11-081990-05-10Hoechst Ag NEW INSULIN DERIVATIVES, THEIR USE AND A PHARMACEUTICAL PREPARATION CONTAINING THEM
HUT56857A (en)1988-12-231991-10-28Novo Nordisk AsHuman insulin analogues
NZ232375A (en)1989-02-091992-04-28Lilly Co EliInsulin analogues modified at b29
DE69024953T3 (en)1989-05-042005-01-27Southern Research Institute, Birmingham encapsulation
US5545618A (en)1990-01-241996-08-13Buckley; Douglas I.GLP-1 analogs useful for diabetes treatment
DK155690D0 (en)1990-06-281990-06-28Novo Nordisk As NEW PEPTIDES
US5272135A (en)1991-03-011993-12-21Chiron Ophthalmics, Inc.Method for the stabilization of methionine-containing polypeptides
DK36392D0 (en)1992-03-191992-03-19Novo Nordisk As USE OF CHEMICAL COMPOUND
US5846747A (en)1992-03-251998-12-08Novo Nordisk A/SMethod for detecting glucagon-like peptide-1 antagonists and agonists
DK39892D0 (en)1992-03-251992-03-25Bernard Thorens PEPTIDE
US5424286A (en)1993-05-241995-06-13Eng; JohnExendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same
JP2837956B2 (en)1993-06-211998-12-16ノボ ノルディスク アクティーゼルスカブ Asp ▲ B28 ▼ Insulin crystal
JPH09505308A (en)1993-11-191997-05-27アルカーミズ・コントロールド・セラピューティクス・インコーポレイテッド・トゥー Production of biodegradable microparticles containing biologically active agents
US5705483A (en)1993-12-091998-01-06Eli Lilly And CompanyGlucagon-like insulinotropic peptides, compositions and methods
KR100600457B1 (en)1996-06-052006-07-13로셰 디아그노스틱스 게엠베하 Exendin analogs, preparation methods thereof, and pharmaceuticals containing the same
DE19637230A1 (en)1996-09-131998-03-19Boehringer Mannheim Gmbh Exendin analogues, process for their preparation and medicaments containing them
EP0910402B1 (en)*1996-06-202007-08-08Novo Nordisk A/SInsulin preparations containing mannitol
US5948751A (en)*1996-06-201999-09-07Novo Nordisk A/SX14-mannitol
JP4404380B2 (en)*1996-06-202010-01-27ノボ ノルディスク アクティーゼルスカブ NaCl-containing insulin preparation
US6110703A (en)1996-07-052000-08-29Novo Nordisk A/SMethod for the production of polypeptides
ES2359031T3 (en)1996-08-082011-05-17Amylin Pharmaceuticals, Inc. PHARMACEUTICAL COMPOSITION THAT INCLUDES AN EXENDIN-4 PEPTIDE.
US6006753A (en)1996-08-301999-12-28Eli Lilly And CompanyUse of GLP-1 or analogs to abolish catabolic changes after surgery
US6277819B1 (en)1996-08-302001-08-21Eli Lilly And CompanyUse of GLP-1 or analogs in treatment of myocardial infarction
US6268343B1 (en)1996-08-302001-07-31Novo Nordisk A/SDerivatives of GLP-1 analogs
UA65549C2 (en)1996-11-052004-04-15Елі Ліллі Енд КомпаніUse of glucagon-like peptides such as glp-1, glp-1 analog, or glp-1 derivative in methods and compositions for reducing body weight
AU739020B2 (en)1997-01-072001-10-04Amylin Pharmaceuticals, Inc.Use of exendins and agonists thereof for the reduction of food intake
WO1998035033A1 (en)1997-02-051998-08-131149336 Ontario Inc.Polynucleotides encoding proexendin, and methods and uses thereof
US5846937A (en)1997-03-031998-12-081149336 Ontario Inc.Method of using exendin and GLP-1 to affect the central nervous system
ES2190087T3 (en)1997-06-132003-07-16Genentech Inc STABILIZED FORMULATION OF AN ANTIBODY.
PE79099A1 (en)1997-06-131999-08-24Lilly Co Eli STABLE INSULIN FORMULATIONS
NZ502592A (en)1997-08-082002-03-28Amylin Pharmaceuticals IncExendin agonist peptides and their use in the treatment of type I and II diabetes
ID24890A (en)*1997-10-242000-08-31Lilly Co Eli INSULIN COMPOSITIONS THAT CANNOT BE SOLUTED
US6444641B1 (en)1997-10-242002-09-03Eli Lilly CompanyFatty acid-acylated insulin analogs
JP2003522721A (en)1997-11-142003-07-29アミリン・ファーマシューティカルズ,インコーポレイテッド New exendin agonist compounds
ATE383867T1 (en)1997-11-142008-02-15Amylin Pharmaceuticals Inc NOVEL EXENDIN AGONISTS
EP1049486A4 (en)1997-12-052006-01-04Lilly Co EliGlp-1 formulations
AU759058C (en)1998-02-132005-09-15Amylin Pharmaceuticals, Inc.Inotropic and diuretic effects of exendin and GLP-1
EP1056775B1 (en)1998-02-272010-04-28Novo Nordisk A/SGlp-1 derivatives of glp-1 and exendin with protracted profile of action
EP1950223A3 (en)1998-03-092009-05-13Zealand Pharma A/SPharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
ATE269103T1 (en)1998-03-132004-07-15Novo Nordisk As STABILIZED AQUEOUS GLUCAGON SOLUTIONS CONTAINING DETERGENTS
JP2002516880A (en)1998-06-052002-06-11テクニオン リサーチ アンド デベロップメント ファウンデーション リミテッド Insulin supplemented infant formula
EP1119625B1 (en)1998-10-072005-06-29Medical College Of Georgia Research Institute, Inc.Glucose-dependent insulinotropic peptide for use as an osteotropic hormone
US6284725B1 (en)1998-10-082001-09-04Bionebraska, Inc.Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue
US6211144B1 (en)1998-10-162001-04-03Novo Nordisk A/SStable concentrated insulin preparations for pulmonary delivery
US6489292B1 (en)1998-11-182002-12-03Novo Nordisk A/SStable aqueous insulin preparations without phenol and cresol
JP2007204498A (en)1999-03-012007-08-16Chugai Pharmaceut Co LtdLong-term stabilized formulations
JP2000247903A (en)1999-03-012000-09-12Chugai Pharmaceut Co LtdLong-term stabilized pharmaceutical preparation
US6271241B1 (en)1999-04-022001-08-07Neurogen CorporationCycloalkyl and aryl fused aminoalkyl-imidazole derivatives: modulators and GLP-1 receptors
WO2000066629A1 (en)1999-04-302000-11-09Amylin Pharmaceuticals, Inc.Modified exendins and exendin agonists
WO2000069911A1 (en)1999-05-172000-11-23Conjuchem, Inc.Long lasting insulinotropic peptides
US6344180B1 (en)1999-06-152002-02-05Bionebraska, Inc.GLP-1 as a diagnostic test to determine β-cell function and the presence of the condition of IGT and type II diabetes
US6528486B1 (en)1999-07-122003-03-04Zealand Pharma A/SPeptide agonists of GLP-1 activity
EP1076066A1 (en)1999-07-122001-02-14Zealand Pharmaceuticals A/SPeptides for lowering blood glucose levels
DE19947456A1 (en)1999-10-022001-04-05Aventis Pharma GmbhNew synthetic derivatives of the C-peptide of proinsulin, useful in the preparation of human insulin or insulin analogs in high yield
PL211886B1 (en)1999-10-042012-07-31Novartis Vaccines & DiagnosticStabilized liquid polypeptide-containing pharmaceutical compositions
US20010012829A1 (en)2000-01-112001-08-09Keith AndersonTransepithelial delivery GLP-1 derivatives
AU2353701A (en)2000-01-112001-07-24Novo Nordisk A/STransepithelial delivery of glp-1 derivatives
US6395767B2 (en)2000-03-102002-05-28Bristol-Myers Squibb CompanyCyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
WO2002067969A2 (en)2001-02-212002-09-06Medtronic Minimed, Inc.Stabilized insulin formulations
DE10114178A1 (en)2001-03-232002-10-10Aventis Pharma Gmbh Zinc-free and low-zinc insulin preparations with improved stability
EP1377608B1 (en)2001-04-022009-09-16Novo Nordisk A/SInsulin precursors and a process for their preparation
US7156877B2 (en)2001-06-292007-01-02The Regents Of The University Of CaliforniaBiodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs
JP2005508895A (en)2001-08-282005-04-07イーライ・リリー・アンド・カンパニー Premix of GLP-1 and basal insulin
HUP0700126A2 (en)2001-12-202007-06-28Lilly Co EliInsulin molecule having protracted time action
AU2003203146A1 (en)2002-02-072003-09-02Novo Nordisk A/SUse of glp-1 compound for treatment of critically ill patients
JP2005526126A (en)2002-05-072005-09-02ノボ ノルディスク アクティーゼルスカブ Soluble preparation containing insulin aspart and insulin detemia
ATE496064T1 (en)2002-05-072011-02-15Novo Nordisk As SOLUBLE FORMULATIONS CONTAINING MONOMERIC INSULIN AND ACYLATED INSULIN
DE10227232A1 (en)2002-06-182004-01-15Aventis Pharma Deutschland Gmbh Sour insulin preparations with improved stability
EP2028192A1 (en)2002-07-042009-02-25Zealand Pharma A/SGLP-1 and methods for treating diabetes
KR20050083713A (en)2002-10-022005-08-26질랜드 파마 에이/에스Stabilized exendin-4 compounds
MXPA05009565A (en)2003-03-112005-12-02Novo Nordisk AsPharmaceutical preparations comprising acid-stabilised insulin.
DE10325567B4 (en)2003-06-052008-03-13Mavig Gmbh Radiation protection arrangement with separable enclosure
EP1663295A2 (en)2003-09-012006-06-07Novo Nordisk A/SStable formulations of peptides
TW200522976A (en)2003-09-192005-07-16Novo Nordisk AsNovel plasma protein affinity tags
ES2373660T3 (en)2003-11-132012-02-07Novo Nordisk A/S PHARMACEUTICAL COMPOSITION THAT INCLUDES AN INSULINOTROPIC GLP-1 ANALOG (7-37), ASP INSULIN (B28) AND A TENSIOACTIVE.
US20050201978A1 (en)2003-11-172005-09-15Lipton James S.Tumor and infectious disease therapeutic compositions
US20080090753A1 (en)2004-03-122008-04-17Biodel, Inc.Rapid Acting Injectable Insulin Compositions
JP5000493B2 (en)2004-05-202012-08-15ディアメディカ インコーポレイテッド Pharmaceutical composition for treating insulin resistance, method of using bethanechol and N-acetylcysteine in the preparation of said pharmaceutical composition and kit comprising said pharmaceutical composition
US20060073213A1 (en)2004-09-152006-04-06Hotamisligil Gokhan SReducing ER stress in the treatment of obesity and diabetes
US20080280814A1 (en)2004-09-172008-11-13Novo Nordisk A/SPharmaceutical Compositions Containing Insulin and Insulinotropic Peptide
EP2494983B1 (en)2004-11-122019-04-24Novo Nordisk A/SStable formulations of glp-1
ES2575984T3 (en)2004-11-122016-07-04Novo Nordisk A/S Stable formulations of peptides containing an acylated GLP-1 analogue and a basal insulin
WO2006053906A1 (en)*2004-11-222006-05-26Novo Nordisk A/SSoluble, stable insulin-containing formulations with a protamine salt
DE102004058306A1 (en)2004-12-012006-07-27Sanofi-Aventis Deutschland Gmbh Process for the preparation of carboxy-terminally amidated peptides
WO2006083952A2 (en)2005-02-012006-08-10Canberra Industries, Inc.Maximum entropy signal detection method
ATE509634T1 (en)2005-04-082011-06-15Amylin Pharmaceuticals Inc PHARMACEUTICAL FORMULATIONS CONTAINING INCRETIN PEPTIDE AND APROTIC-POLAR SOLVENT
EP1888118B1 (en)2005-05-252016-08-17Novo Nordisk A/SPolypeptide formulations stabilized with ethylenediamine
WO2006131730A1 (en)2005-06-062006-12-14Camurus AbGlp-1 analogue formulations
DE102005046113A1 (en)2005-09-272007-03-29Sanofi-Aventis Deutschland GmbhPreparation of C-amidated peptides, useful as pharmaceuticals, by reaction between precursor peptides in presence of enzyme with activity of trypsin, also new reaction products
KR101105871B1 (en)2005-09-272012-01-16주식회사 엘지생명과학 Stable Solution Formulation of Phosphorus Follicle Stimulating Hormone
EP1933884B1 (en)2005-10-112017-09-06Huntington Medical Research InstitutesImaging agents and methods of use thereof
US8343914B2 (en)2006-01-062013-01-01Case Western Reserve UniversityFibrillation resistant proteins
WO2007082381A1 (en)2006-01-202007-07-26Diamedica Inc.Compositions containing (s)-bethanechol and their use in the treatment of insulin resistance, type 2 diabetes, glucose intolerance and related disorders
US20070191271A1 (en)2006-02-102007-08-16Dow Pharmaceutical SciencesMethod for stabilizing polypeptides lacking methionine
EP1986674A4 (en)2006-02-132009-11-11Nektar TherapeuticsMethionine-containing protein or peptide compositions and methods of making and using
EP1996224B1 (en)2006-03-152012-11-07Novo Nordisk A/SMixtures of amylin and insulin
WO2007113205A1 (en)2006-04-032007-10-11Novo Nordisk A/SGlp-1 peptide agonists
EP2015769A4 (en)2006-04-132013-12-25Ipsen PharmaPharmaceutical compositions of hglp-1, exendin-4 and analogs thereof
DE102006031962A1 (en)2006-07-112008-01-17Sanofi-Aventis Deutschland Gmbh Amidated insulin glargine
US20090318353A1 (en)2006-08-252009-12-24Novo Nordisk A/SAcylated Exendin-4 Compounds
DK2074141T3 (en)2006-09-222016-11-28Novo Nordisk AsThe protease resistant insulin analogues.
WO2008124522A2 (en)2007-04-042008-10-16Biodel, Inc.Amylin formulations
MX2009011123A (en)2007-04-232009-11-02Intarcia Therapeutics IncSuspension formulations of insulinotropic peptides and uses thereof.
CN101366692A (en)2007-08-152009-02-18江苏豪森药业股份有限公司Stable Exenatide formulation
GB0717399D0 (en)2007-09-072007-10-17Uutech LtdUse of GLP-1 analogues for the treatment of disorders associated with dysfunctional synaptic transmission
SI2219607T1 (en)2007-11-012012-09-28Merck Serono SaLiquid LH formulations
WO2009060071A1 (en)*2007-11-082009-05-14Novo Nordisk A/SInsulin derivative
MX2010005245A (en)2007-11-162010-06-01Novo Nordisk AsPharmaceutical compositions containing insulin and an insulinotropic peptide.
CN101444618B (en)2007-11-262012-06-13杭州九源基因工程有限公司Pharmaceutical preparation containing exenatide
WO2009075859A2 (en)2007-12-112009-06-18Conjuchem Biotechnologies Inc.Formulation of insulinotropic peptide conjugates
ES2613152T3 (en)2008-01-092017-05-22Sanofi-Aventis Deutschland Gmbh New insulin derivatives with extremely delayed time / action profile
JP5695909B2 (en)2008-01-092015-04-08サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Novel insulin derivatives with extremely delayed time action profiles
WO2009102467A2 (en)2008-02-132009-08-20Intarcia Therapeutics, Inc.Devices, formulations, and methods for delivery of multiple beneficial agents
TWI394580B (en)2008-04-282013-05-01Halozyme IncSuper fast-acting insulin compositions
KR100928942B1 (en)*2008-05-262009-11-30제이에스아이실리콘주식회사 Process for producing straight or cyclic trisila alkanes
KR20110076918A (en)2008-09-102011-07-06제넨테크, 인크. Compositions and Methods for Preventing Oxidative Degradation of Proteins
CN101670096B (en)2008-09-112013-01-16杭州九源基因工程有限公司Medicinal preparation containing exenatide
US20100092566A1 (en)2008-10-152010-04-15Alessi Thomas RHighly concentrated drug particles, formulations, suspensions and uses thereof
CR20170369A (en)2008-10-172017-11-01Sanofi Aventis Deutschland COMBINATION OF AN INSULIN AND A GLP-1 AGONIST (Divisional 2011-0188)
JP2009091363A (en)2008-11-212009-04-30Asahi Kasei Pharma KkStabilized aqueous injectable solution of pth
CN102596175A (en)2009-07-062012-07-18赛诺菲-安万特德国有限公司Aqueous insulin preparations containing methionine
TW201113032A (en)2009-07-062011-04-16Sanofi Aventis DeutschlandSlow-acting insulin preparations
JP2012532177A (en)2009-07-062012-12-13サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Thermal and vibration stable insulin formulations
AU2010277560B2 (en)2009-07-312014-12-11Sanofi-Aventis Deutschland GmbhLong acting insulin composition
AR078161A1 (en)2009-09-112011-10-19Hoffmann La Roche VERY CONCENTRATED PHARMACEUTICAL FORMULATIONS OF AN ANTIBODY ANTI CD20. USE OF THE FORMULATION. TREATMENT METHOD
WO2011058082A1 (en)2009-11-132011-05-19Sanofi-Aventis Deutschland GmbhPharmaceutical composition comprising a glp-1 agonist and methionine
US20110118178A1 (en)2009-11-132011-05-19Sanofi-Aventis Deutschland GmbhMethod of treatment of diabetes type 2 comprising add-on therapy to insulin glargine and metformin
US20110118180A1 (en)2009-11-132011-05-19Sanofi-Aventis Deutschland GmbhMethod of treatment of diabetes type 2 comprising add-on therapy to metformin
PL2498802T3 (en)2009-11-132015-06-30Sanofi Aventis DeutschlandPharmaceutical composition comprising a glp-1 agonist, an insulin, and methionine
AU2011202239C1 (en)2010-05-192017-03-16SanofiLong-acting formulations of insulins
EP2389945A1 (en)2010-05-282011-11-30Sanofi-Aventis Deutschland GmbHPharmaceutical composition comprising AVE0010 and insulin glargine
SG187904A1 (en)2010-08-302013-04-30Sanofi Aventis DeutschlandUse of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
WO2012080320A1 (en)2010-12-142012-06-21Novo Nordisk A/SFast-acting insulin in combination with long-acting insulin
KR20140041409A (en)2011-02-022014-04-04사노피-아벤티스 도이칠란트 게엠베하Prevention of hypoglycaemia in diabetes mellitus type 2 patients
US20120277147A1 (en)2011-03-292012-11-01Sanofi-Aventis Deutschland GmbhPrevention of hypoglycaemia in diabetes mellitus type 2 patients
US20130040878A1 (en)2011-05-132013-02-14Sanofi-Aventis Deutschland GmbhPharmaceutical combination for use in the treatment of diabetes type 2 patients
US8735349B2 (en)2011-05-132014-05-27Sanofi-Aventis Deutschland GmbhMethod for improving glucose tolerance in a diabetes type 2 patient of younger than 50 years and having postprandial plasma glucose concentration of at least 14 mmol/L
JP6442284B2 (en)2011-05-132018-12-19サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Lixisenatide and metformin for the treatment of type 2 diabetes
US9821032B2 (en)2011-05-132017-11-21Sanofi-Aventis Deutschland GmbhPharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
EP2750699B1 (en)2011-08-292015-07-22Sanofi-Aventis Deutschland GmbHPharmaceutical combination for use in glycemic control in diabetes type 2 patients
EP2763691A1 (en)2011-10-042014-08-13Sanofi-Aventis Deutschland GmbHGlp-1 agonist for use in the treatment of stenosis or/and obstruction in the biliary tract
SI2763690T1 (en)2011-10-042016-03-31Sanofi-Aventis Deutschland GmbhLixisenatide for use in the treatment of stenosis or/and obstruction in the pancreatic duct system
AU2012328388B2 (en)2011-10-282017-06-15Sanofi-Aventis Deutschland GmbhTreatment protocol of diabetes type 2
US8901484B2 (en)2012-04-272014-12-02Sanofi-Aventis Deutschland GmbhQuantification of impurities for release testing of peptide products
AR092862A1 (en)2012-07-252015-05-06Hanmi Pharm Ind Co Ltd LIQUID FORMULATION OF PROLONGED ACTION INSULIN AND AN INSULINOTROPIC PEPTIDE AND PREPARATION METHOD
TWI641381B (en)2013-02-042018-11-21法商賽諾菲公司 Stabilized pharmaceutical formulations of insulin analogs and/or insulin derivatives
GB201303771D0 (en)2013-03-042013-04-17Midatech LtdNanoparticles peptide compositions
JP6641280B2 (en)2014-01-092020-02-05サノフイSanofi Stabilized pharmaceutical formulations of insulin analogues and / or insulin derivatives
MX2016008977A (en)*2014-01-092016-10-04Sanofi SaStabilized pharmaceutical formulations of insulin aspart.
CN105899191B (en)2014-01-092020-06-16赛诺菲Stabilized glycerol-free pharmaceutical formulations of insulin analogues and/or insulin derivatives

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MX2016008977A (en)2016-10-04
US20180125944A1 (en)2018-05-10
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WO2015104310A1 (en)2015-07-16
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JP2017503797A (en)2017-02-02
US20220023392A1 (en)2022-01-27
JP2022180537A (en)2022-12-06
JP6735674B2 (en)2020-08-05
AU2015205620A1 (en)2016-07-14
EP3091964A1 (en)2016-11-16
CN105899190A (en)2016-08-24
CN114939156A (en)2022-08-26
RU2016132340A (en)2018-02-14
BR112016015851A2 (en)2017-08-08
RU2016132340A3 (en)2018-09-18
US20150190475A1 (en)2015-07-09
CN105899190B (en)2022-06-14

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